Abstract: A three-component mixing apparatus and a three-component mixing adhesive kit, which allow anyone to easily and uniformly mix three kinds of drugs in mixing a three-component adhesive used in, e.g., surgical procedure (or treatment) or dental procedure (or treatment), includes a syringe filled with a first drug; a plunger; and an infusion-needle connector having a connecting part for a second drug container and a connecting part for a third drug container and a confluent path formed on a base end part. The first drug, the second drug and the third drug are mixed in the syringe by removably attaching the infusion-needle connector to a discharge opening of the syringe, the second drug container to its connecting part and the third drug container to its connecting part and then pulling the plunger inserted into the syringe to introduce the second drug and the third drug into the syringe.

Abstract: Mixer for biphasic compounds, including a chamber for containing a solid phase and a cartridge containing a phial of a liquid phase, said chamber and said cartridge being able to communicate through respective channels, wherein said cartridge includes an external casing made in a deformable material and said phial is of the breakable type.

Abstract: A plasticizing system (100) for plasticizing a solidified-resin particle (202), the plasticizing system (100), comprising: (A) opposite-facing surfaces (104) being spaced apart from each other, and defining, at least in part, a convergence channel (105) being configured to receive the solidified-resin particle (202), and (B) a plunger assembly (124) being movable, at least in part, relative to the opposite-facing surfaces (104), the plunger assembly (124) being configured to move, at least in part, the solidified-resin particle (202) relative to the opposite-facing surfaces (104) along, at least in part, the convergence channel (105).

Abstract: Convening dewatered heterogeneous sludge containing organic waste materials into a homogenous extract of carbon and amino acids for fertilizer production by adding sulfuric acid to the sludge; pumping the mixture through a blending mixer to mix the sludge with the sulfuric acid; adding conditioning chemicals to the mixture: pumping the mixture through a shearing mixer to mix the conditioning chemicals into the mixture; and mechanically agitating the mixture to create the homogenous extract. Optionally, the extract is pumped into a pipe reactor for reaction with an acid and a base to form a melt, which is rolled onto fertilizer particles to form accreted granules. The accreted granules are dried to form a granular fertilizer. Also described is an organically-enhanced granular nitrogen-phosphorous-sulfur fertilizer having at least about 0.5% by weight total carbon and amino acids, and accreted granule size greater than or equal to about 1.7 mm. The fertilizer is noncombustible.

Abstract: Plasticizing system for plasticizing solidified-resin particle, plasticizing system, comprising: housing assembly providing: (i) melt channel configured to receive solidified-resin particle, and (ii) opposite-facing surfaces spaced apart from each other, and defining, at least in part, convergene channel configured to receive the solidified-resin particle. Opposite-facing surfaces and the convergence channel form part of melt channel. Plunger assembly is movable, at least in part, relative to opposite-facing surfaces. Plunger assembly configured to move, at least in part, solidified-resin particle relative to opposite-facing surfaces along, at least in part, convergence channel. In response to relative movement between solidified-resin particle and opposite-facing surfaces, solidified-resin particle receives, in use, plasticization-inducing effect from opposite-facing surfaces.

Abstract: A method of forming fine particles of a drug substance using a piston-gap high pressure homogeniser.

Abstract: Mixing devices and systems are disclosed for storing separate components and for mixing and dispensing those Components on demand. A mixing device includes a syringe having a generally tubular housing formed with a mixing chamber. A plunger is fitted to the tubular housing to form a first syringe. A dispensing syringe is releasably connected to the mixing chamber. At this point each syringe holds a desired amount of a mixture component. The contents of one syringe are passed through the mixing chamber to the other syringe, forming a usually incomplete mixture. The mixture is then passed through the mixing chamber to the other syringe. Multiple passes through the mixing chamber are continued until the desired mixing result is achieved, and the mixture material is contained in the second syringe that is used to thereafter dispense desired amounts of the mixture.

Abstract: A high pressure homogenizer provided with head for the treatment of products with solids and fibers comprises a block defining a passage for the product from an intake area to a delivery area, a piston movable axially with reciprocating motion in the block to pump the product in said passage, intake and delivery valves positioned internally to the block and operatively active on said passage to open it/close as a function of a motion of the products in the passage. The passage is positioned in the block in position of non-interference with the motion of the piston and the intake and delivery valves have no springs and are operatively inserted in said passage in intermediate position between said intake and delivery areas, to favor the sliding of the products and to prevent the accumulation of substances that are sensitive to shear effects contained in the products themselves.

Abstract: Mixing devices and systems are disclosed for storing separate components and for mixing and dispensing those components on demand. A mixing device includes a syringe having a generally tubular housing formed with a mixing chamber. A plunger is fitted to the tubular housing to form a first syringe. A dispensing syringe is releasably connected to the mixing chamber. At this point each syringe holds a desired amount of a mixture component. The contents of one syringe are passed through the mixing chamber to the other syringe, forming a usually incomplete mixture. The mixture is then passed through the mixing chamber to the other syringe. Multiple passes through the mixing chamber are continued until the desired mixing result is achieved, and the mixture material is contained in the second syringe that is used to thereafter dispense desired amounts of the mixture.

Abstract: A universal mixer for mixing two or more components is provided. The mixer comprises two telescopically nested cylinders, the inner cylinder having a piston that stays in place due to hydraulic pressure inside the cylinders. The components to be mixed are inserted into a space formed by the outer cylinder, a cap and a gasket having one or more holes. The user forces the compounds through the holes by holding the handles of the mixer and pushing a back handle forward thereby causing the inner cylinder to move forward. The inner cylinder preferably has a diameter that narrows slightly from its back to front end. Further mixing is achieved by pulling the back handle backwards whereby the components are squeezed between the piston and the gasket and the components move through the holes in the gasket into the container formed by the outer cylinder.

Abstract: The invention relates to the use of a homogenisation valve that comprises a flap gate (1), an impact ring (3) and a seat in order to prepare, using high-pressure valve technology, a nanosuspension of a solid pharmaceutically active principle, characterized in that the material constituting the flap gate, the seat and optionally the impact ring and/or the outer surface of at least one of said elements includes sintered or hot-pressed silicon nitride as the main component. The invention also relates to a method for preparing a nanosuspension of a solid pharmaceutically active principle using the high-pressure valve homogenization technology.

Abstract: A bone cement system (100) is provided having a mixing facility (10) for mixing and dispensing of bone cement, a reservoir container (112) for a monomer, and a conveyor (122). The mixing facility (10) has a mixing cylinder (20), which stores a bone cement powder. The monomer can be conveyed from the reservoir container (112) into the mixing cylinder (20) by the conveyor (122). A sieve element is (4) is arranged between the reservoir container (112) and the mixing facility (10), in order to preventingress of the bone cement powder from the mixing cylinder (20) into the conveyor (122). The mixing device (10) included a dispensing opening (23) for dispensing a bone cement mixed from the bone cement powder and the monomer. The dispensing opening (23) includes a shield (1) having at least one through-opening (2). The ratio of the area of the through-opening (2) to the area of the sieve element (4) is at least 1 to 3, and the distance between the shield (1) and the sieve element (4) is at least 1 mm.

Abstract: A sealed mixer comprises a housing provided with a mixing chamber and a material insertion port for inserting materials into the mixing chamber; a weight for pressing the materials inserted into the material insertion port toward the mixing chamber; and a shaft member which extends upward from the weight and moves upward and downward together with the weight, the weight being connected to a lower end portion of the shaft member, a reservoir adapted to store lubricant between the weight and the shaft member is formed at a part connecting the weight and the shaft member, and a lubricant supply path adapted to supply the lubricant from an outside toward the reservoir is formed in the shaft member.

Abstract: An apparatus and method for blending a predetermined fluid with a main fluid wherein a source of a predetermined fluid is mixed with a main fluid. The predetermined fluid flows through an inlet of a positive displacement pump assembly and transferred to a mixing chamber through an outlet of the positive displacement pump assembly. A turbine blade assembly located within the mixing chamber is used to mix a main fluid flowing into the mixing chamber with the predetermined fluid for eventual dispensing through an outlet in the mixing chamber when desired.

Abstract: A device for preparing a liquid mixture that is to be applied to a printing material is provided. The device includes a first reservoir containing a first ingredient of the liquid mixture, a supply source for a second ingredient of the liquid mixture, a mixing tank for receiving the at least first and second ingredients and for mixing the ingredients to obtain the liquid mixture, and supply lines to convey the first ingredient and the second ingredient from the first reservoir and the supply source to the mixing tank. The first ingredient includes less than 60, preferably less than 50, and most preferably less than 25 weight % of water, and in particular is an essentially waterless ingredient. A method is also provided.

Abstract: An injector device is disclosed, the injector device comprising an elongated mixing container extending along a first axis, and a piston member slidably positioned in the mixing container. The injector device comprises a mixing device comprising a mixing member, an elongated member parallel to the first axis and a handle member. The piston member comprises a piston head and a first locking arm flexibly connected to the piston head, such that the first locking arm in a first position extends substantially parallel to the elongated member and engages with the mixing device in such a way that the piston member moves in a first direction along the first axis with the mixing device. In a second position, the first locking arm may allow the mixing device to move relative to the mixing container independently of the piston member.

Abstract: A homogenizer valve includes two or more pressurized, movable valve cones, two or more valve seats and a valve housing which surrounds the valve cones and the valve seats. The valve cones and the valve seats are disposed so that throttles occur between them, which constitute homogenization gaps, which have a gap height h. The homogenization gaps are disposed at an angle in relation to the horizontal plane. The homogenizer valve is intended to be used in existing homogenizers and has been particularly produced to be able to obtain an efficient homogenization for liquids which are processed at a lower pressure and with a greater flow, such as, for example, pasteurized milk.

Abstract: A homogenizer valve (1) comprising a ring-shaped first chamber (5) with an inlet (8) for receiving fluid under high pressure, a second ring-shaped chamber (7) with an outlet (9) for fluid under low pressure, a passage head (10) and, between the first and the second chamber, an impact head (11) which is axially mobile with respect to the passage head (10) and acts together with it to define a gap between the impact head (11) and the passage head (10) forming a passage (14) for the fluid passing from the first chamber to the second chamber, and a pusher (15) acting on the impact head (11) to push it in an axial direction towards the passage head (10) thus partially counteracting the pressure exerted by the fluid contained in the first chamber (5) on the annular surface (13) of the impact head (11), this passage (14) comprising at least a first portion (20) and a second portion (21) positioned in sequence between the first chamber and the second chamber, and where the first portion faces in a radial direction an

Abstract: An active ingredient, such as particles of a pharmaceutical agent, is uniformly distributed within a transdermal vehicle, such as a gel or other viscous material. The method comprises filling said first container with a non-uniform mixture of a transdermal vehicle and said active ingredient, mounting the first container on a support member, and securing a second container to the first container. The first container has a restricted opening at its proximal end and a piston mounted movably within the first container for movement between a first position proximate said first container distal end to a position proximate said first container proximal end. The second container has a restricted opening at its proximal end and a piston mounted movably within the first container for movement from a first position proximate the second container distal end to a position proximate said second container proximal end.

Abstract: A device for producing a multi-component compound, in particular for dental purposes, by mixing its components after they have been pressed out of cartridges which open into a dynamic mixer and are arranged exchangeably in the device, with a first motor for advancing all of the pistons assigned to the cartridges, and with a second motor for rotary driving of mixing elements in the mixer via a shaft, which is held in engagement with the mixer by spring pretensioning and can be pulled back from the mixer counter to the spring pretensioning, is characterized in that the shaft is provided with a radially extending projection which, by means of the spring pretensioning, is pressed onto a ramp-like upwardly sloping cam surface, which is provided on its foot with an abutment surface, of a toothed wheel, which is provided with saw-like teeth and is coaxial to the shaft, which toothed wheel, in a first angle direction in which the cam surface slopes upwards, is prevented from rotating by a catch and, in the second ang

Abstract: A homogeniser (1) for the continuous treatment of fluids at very high pressure comprises at least one reciprocating plunger (5) in a compression chamber (6) and a guide chamber (11) from a fluid intake position to a delivery position. Said compression chamber (6) opens into a manifold (27), inside a block (26) from which a delivery pipe (32) and an intake pipe (31) branch off. A first seal unit (21) is housed in the guide chamber (11), a second seal unit (24) is located close to the intersection between the compression chamber (6) and the guide chamber (11) and a third seal unit (35) is positioned upstream and downstream of each valve (28, 29) and the intersection between the manifold (27) and the compression chamber (6).

Abstract: A fractionable polydisperse stable double oil-in-water emulsion, having 50 to 95 wt. % relative to the total weight of the double emulsion, droplets of an invert monodisperse emulsion Ei dispersed in a continuous aqueous phase. The continuous aqueous phase includes a polysaccharide thickening agent in a proportion of 1 to 10 wt. % relative to the total weight of the continuous aqueous phase, a water-soluble ethylene oxide and propylene oxide block copolymer as surfactant, and an osmotic pressure balancing agent. The emulsion Ei has a viscosity not higher than the viscosity of the continuous aqueous phase and has 50 to 95 wt. %, relative to the total weight of Ei, droplets of an internal aqueous phase dispersed in an oily phase. The internal aqueous phase includes an active hydrophilic substance and the oily phase includes poly glycerol polyricinoleate as surfactant.

Abstract: A cascading orifice mixer for mixing a viscoelastic material comprising a plurality of chambers connected in series, including a first chamber, at least one intermediate chamber and a last chamber, each chamber including an orifice providing fluid communication between adjacent chambers thereby defining a substantially unidirectional sequential flow path through the chambers is disclosed. Each chamber has a variable volume ranging from a minimum volume to a maximum volume and the chambers are adapted to transport the viscoelastic material along the sequential flow path by transporting the viscoelastic material from a filled chamber containing a quantity of the viscoelastic material to a next adjacent empty chamber wherein the filled chamber and the next adjacent chamber are each at or near the maximum volume for the respective chamber.

Abstract: A device for mixing and metering one or multi-component compounds from at least one cartridge. These compounds can be in the form of a basic component and a catalyst component for impression compounds for dental applications. This device includes a punch for admitting pressure to the cartridge. This punch is supported in a displaceable manner, and is associated with each cartridge. This device also includes a hydraulic circuit which is associated with said at least one punch so that it actuates a piston or a cylinder of a hydraulically actuated piston cylinder unit. This device includes at least one pump and a supply container. This invention also includes a valve arrangement for this device.

Abstract: A method and apparatus for mixing a polymer with an agglomerates of one or more compounds in a pair of opposed pressure cylinders with a nozzle block there between using moving the pistons to force the polymer with the agglomerates from pressure cylinders into the other and back so that the agglomerates are broken up and dispersed throughout the polymer.

Abstract: A cascading orifice mixer for mixing a viscoelastic material comprising a plurality of chambers connected in series, including a first chamber, at least one intermediate chamber and a last chamber, each chamber including an orifice providing fluid communication between adjacent chambers thereby defining a substantially unidirectional sequential flow path through the chambers is disclosed. Each chamber has a variable volume ranging from a minimum volume to a maximum volume and the chambers are adapted to transport the viscoelastic material along the sequential flow path by transporting the viscoelastic material from a filled chamber containing a quantity of the viscoelastic material to a next adjacent empty chamber wherein the filled chamber and the next adjacent chamber are each at or near the maximum volume for the respective chamber.

Abstract: The present invention relates to a buffer tank as is substantially used for ensuring a constant supply of the spinning machine with a polymer melt in spinning machines. To this end the buffer tank is provided with a compensation chamber whose volume is variable in response to a pressure prevailing in the polymer melt and to a volume flow variation. The polymer melt flows from a polymer melt entry opening to a polymer melt exit opening through the compensation chamber. It is the object of the present invention to make the flow through the compensation chamber uniform. The residence time of the polymer melt in the compensation chamber shall thereby be prevented from having a wide range, the latter resulting in an irregular quality of the yarns produced by the spinning machine because of the time-dependent, mechanical and chemical properties of the polymer melt.

Abstract: An apparatus for making a sterile emulsion, comprising a fluid pathway, a pumping bore, a reciprocable (reciprocal) member, and a valve body. The pumping bore being in fluid communication with the fluid pathway and having a reciprocable member reciprocably disposed in the pumping bore. The reciprocable member having first portion disposed in fluid communication with the fluid pathway and a second portion isolated from the fluid pathway, said second portion having a sterilant passage adjacent thereto. The fluid pathway, reciprocable member first portion and reciprocable member second portion may be sterilized and one or more emulsion constituents may be directed into the fluid pathway defined by the piston apparatus after sterilization. The valve body defines a valve bore in communication with the fluid pathway and a valve plunger disposed therein. The valve body may also be configured to maintain emulsion sterility.

Abstract: Method and apparatus for cutting high viscosity liquid material, said apparatus comprising a cylinder divided into upper and lower tanks by a partition with a central discharge opening, a moveable and elevatable liquid supply pipe with a distal end positioned opposite the discharge opening, the liquid supply pipe being mounted so that it can be raised until its distal end contacts the partition around the discharge opening, and then lowered until there is no contact, means for raising and lowering the liquid supply pipe, the upper tank having peripheral injection ports for injecting a low viscosity liquid into the upper tank, means for feeding high viscosity liquid material into the lower tank and flowing it into the upper tank, means for feeding low viscosity liquid into the liquid supply pipe and for feeding low viscosity liquid into the peripheral injection ports, the high viscosity liquid material flowing from the lower tank into the upper tank when the liquid supply pipe is lowered, the high viscosity li