Mammography Patents (Class 378/37)
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Patent number: 9230311Abstract: Methods of imaging a breast comprising acquiring a sequence of image data sets having differing exposure parameters; and combining the image data sets into a mammography image having greater dynamic range than the dynamic range of any single component image data set. Disclosed methods may further comprise determining an exposure parameter of one or more component image data sets prior to acquiring the sequence of image data sets. The step of determining an exposure parameter of one or more component image data sets may comprise determining exposure duration or an exposure irradiation level. Also disclosed are mammography apparatus and systems to obtain images according to the disclosed methods.Type: GrantFiled: February 1, 2012Date of Patent: January 5, 2016Assignee: Dexela LimitedInventors: Edward Bullard, Spencer Gunn, James Brodrick, Hamdan Amin
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Patent number: 9226721Abstract: In a tomosynthesis system a static focal spot is moved in a direction opposite to and generally synchronized with the directional movement of an x-ray source and X-ray collimator blades are moved during each exposure in synchronization with the shifting of the static focal spot. The synchronized movement of the static focal spot, x-ray tube and collimator blades helps keep the effective focal spot fixed in space relative to the breast, detector or both during the entire duration of the exposure and keeps the x-ray field on the detector and breast static. The shifting collimator blades follow an oscillating pattern over the multiple x-ray exposures of a tomosynthesis scan.Type: GrantFiled: June 30, 2014Date of Patent: January 5, 2016Assignee: HOLOGIC, INC.Inventors: Baorui Ren, Andrew P. Smith, Thomas Farbizio, Zhenxue Jing, Jay Stein
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Patent number: 9211102Abstract: The invention relates to an image plate template for keeping at least one image plate used in medical imaging in order with relation to an imaging object. The template comprising at least receiving means for receiving the at least one image plate and displaying means for displaying information in order to associate a patient with the at least one image plate. The template may also comprise communication means for communicating information from said image plate to an external device for displaying information in order to associate a patient with the at least one image plate.Type: GrantFiled: June 25, 2013Date of Patent: December 15, 2015Assignee: PaloDEx Group OyInventors: Jari Taskinen, Timo Klemola, Kaapo Paulanto, Mika Anttila, Petri Hyypia, Jorma Honkala
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Patent number: 9208556Abstract: Computerized interpretation of medical images for quantitative analysis of multi-modality breast images including analysis of FFDM, 2D/3D ultrasound, MRI, or other breast imaging methods. Real-time characterization of tumors and background tissue, and calculation of image-based biomarkers is provided for breast cancer detection, diagnosis, prognosis, risk assessment, and therapy response. Analysis includes lesion segmentation, and extraction of relevant characteristics (textural/morphological/kinetic features) from lesion-based or voxel-based analyzes. Combinations of characteristics in several classification tasks using artificial intelligence is provided. Output in terms of 1D, 2D or 3D distributions in which an unknown case is identified relative to calculations on known or unlabeled cases, which can go through a dimension-reduction technique.Type: GrantFiled: November 28, 2011Date of Patent: December 8, 2015Assignee: Quantitative Insights, Inc.Inventors: Maryellen L. Giger, Robert Tomek, Jeremy Bancroft Brown, Andrew Robert Jamieson, Li Lan, Michael R. Chinander, Karen Drukker, Hui Li, Neha Bhooshan, Gillian Newstead
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Patent number: 9168014Abstract: A gamma radiation breast imaging apparatus, comprising an object positioning device, defining an imaging space and having as an intended insertion direction of the breast to be imaged, and a gamma camera positioned to image a volume in said imaging space. The gamma camera comprises a collimator with a first plurality of focused pinholes, the individual fields of view of the first pinholes defining a common central field of view having a geometrical center. The apparatus also has a gamma sensitive detector to receive images from the collimator. The first pinholes are provided non-symmetrically with respect to a first plane through said geometrical center that is perpendicular to the collimator and parallel to said intended insertion direction. Hereby, more angular information about the scanned volume can be obtained for the same detector size, in particular when combined with a similar opposite camera.Type: GrantFiled: October 2, 2013Date of Patent: October 27, 2015Assignee: Milabs B.V.Inventor: Frederik Johannes Beekman
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Patent number: 9155511Abstract: In a breast image capturing apparatus having an arm section for moving a radiation source in a left-right direction in front of a subject, providing a shielding member for preventing radiation from being applied to the face of the subject on an arm section, and supporting the shielding member movably relative to the arm section when the face of the subject is abutted to the shielding member and fixedly relative to the arm section when the face of the subject is not abutted to the shielding member.Type: GrantFiled: August 14, 2013Date of Patent: October 13, 2015Assignee: FUJIFILM CorporationInventors: Yasunori Ohta, Takao Kuwabara, Yasuko Yahiro
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Patent number: 9131919Abstract: Versatile ultrasound scanning of a breast is described using an apparatus (1202) including a hand-manipulable compression/scanning assembly (1208). The compression/scanning assembly (1208) comprises an ultrasound transducer (1304) and a compressive member comprising an at least partially conformable membrane (1218) in a substantially taut state, the membrane (1218) having a first surface compressing the breast in a generally chestward direction and a second surface opposite the first surface. The compression/scanning assembly (1208) further comprises a transducer translation mechanism coupled to the ultrasound transducer (1304) and configured to sweep the ultrasound transducer across the second surface of the membrane to scan the breast while compressed in the generally chestward direction. Systemized and/or standardized ultrasonic scanning of a breast based on hand-manipulable scanners (1208, 1508) having substantially planar scanning surfaces is also described.Type: GrantFiled: September 20, 2012Date of Patent: September 15, 2015Assignee: U-Systems, Inc.Inventors: Douglas G. Summers, Shih-Ping Wang, Jiayu Chen, Tor C. Anderson
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Patent number: 9131914Abstract: A compression plate for tomosynthesis images using an X-ray apparatus designed to take the tomosynthesis images is provided. The compression plate includes an upper area. The width of the upper area is dimensioned such that, for all X-ray images taken during tomosynthesis of a female breast compressed by the compression plate, X-rays substantially penetrate the compression plate. The compression plate also includes a lower area. An average width of the lower area is smaller than an average width of the upper area. The lower area includes a surface of smaller width than the width of the upper area for the compression of the female breast.Type: GrantFiled: May 3, 2011Date of Patent: September 15, 2015Assignee: Siemens AktiengesellschaftInventor: Martin Ramsauer
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Patent number: 9129362Abstract: A method, a system, a computer program and a computer program product, as well as a computer-readable storage medium, enables navigating between different medical images and localizing dedicated positions in the images. The medical images may be digital breast tomosynthesis (DBT) images, full-field digital mammography system (FFDM) images and magnetic resonance (MR) images. The process is based on a shape prediction algorithm and a computer-aided detection/diagnosis (CAD) algorithm in order to find a corresponding second position in the at least one second image.Type: GrantFiled: May 22, 2013Date of Patent: September 8, 2015Assignee: Siemens AktiengesellschaftInventor: Anna Jerebko
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Patent number: 9101322Abstract: An X-ray imaging apparatus and an imaging method capable of acquiring an image of a test object associated with a phase shift in consideration of X-ray absorption is provided. A splitting element configured to spatially split an X-ray into multiple X-ray beams is provided. A shielding unit including a plurality of shielding elements configured to block part of an X-ray acquired by the splitting element is provided. Part of X-ray beams detected at the first detection pixels is blocked by the shielding elements. The X-ray beams detected by the second detection pixels adjoining the first detection pixels are not blocked by the shielding elements.Type: GrantFiled: June 20, 2011Date of Patent: August 11, 2015Assignee: Canon Kabushiki KaishaInventors: Taihei Mukaide, Nao Nakatsuji
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Patent number: 9066706Abstract: A system for multi-mode breast x-ray imaging which comprises a compression arm assembly for compressing and immobilizing a breast for x-ray imaging, an x-ray tube assembly, and an x-ray image receptor is provided. The system is configured for a plurality of imaging protocols and modes.Type: GrantFiled: October 21, 2013Date of Patent: June 30, 2015Assignee: Hologic, Inc.Inventors: Kenneth DeFreitas, Thomas Farbizio, Baorui Ren, Christopher Ruth, Ian Shaw, Andrew P. Smith, Jay Stein
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Patent number: 9060732Abstract: A system and method for molecular breast imaging (MBI) provides enhanced tumor analysis and, optionally, a real-time biopsy guidance. The system includes a detector head including a gamma ray detector and a multisegment collimator in a collimator frame. The collimator contains multiple collimation sections that have respectively different collimating characteristic and that are individually repositionable with respect to the detector. An image of the tissue acquired with the system may include spatially separate image portions containing image information about the same portion of the imaged tissue. A system of mounting the multisegment collimator in the detector head includes a collimator tray that is laterally moveable within the frame and/or slidable in and out of the frame.Type: GrantFiled: December 14, 2012Date of Patent: June 23, 2015Assignee: Mayo Foundation for Medical Education and ResearchInventor: Michael K. O'Connor
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Patent number: 9064329Abstract: A method of reconstructing a tomography image of an object from a plurality of projection images generated by scanning the object in a plurality of projection directions includes: determining whether a truncated portion of the object exists in the plurality of projection images; reconstructing a first reconstruction image; calculating projection data for the first reconstruction image; and reconstructing a tomography image of the object by using the calculated projection data.Type: GrantFiled: February 28, 2013Date of Patent: June 23, 2015Assignees: SAMSUNG ELECTRONICS CO., LTD., KOREA ADVANCED INSTITUTE OF SCIENCE AND TECHNOLOGYInventors: Jong-ha Lee, Young-hun Sung, Kang-eui Lee, Kwang-eun Jang, Seung-ryong Cho
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Patent number: 9036774Abstract: A press plate that includes: a plate shaped press portion that is capable of resilient deformation; a first slit that is provided to a first wall portion of a support body with length direction along a first edge portion of the press portion, and that penetrates the first wall portion; second slits that are provided to a second wall portions of the support body with length direction along second edge portions of the press portion, and that penetrate the second wall portions; and a first corner portion slit that is provided straddling a corner portion between the first wall portion and the second wall portion and penetrating the corner portion, that is connected to the first slit, and that is disposed at a separation to the second slit.Type: GrantFiled: December 24, 2013Date of Patent: May 19, 2015Assignee: FUJIFILM CorporationInventors: Shinji Otokuni, Kenji Takata, Tomoki Inoue
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Publication number: 20150131778Abstract: A method and system for producing tomosynthesis images of a breast specimen in a cabinet x-ray system. An X-ray source delivers X-rays through a specimen of excised tissue and forms an image at a digital X-ray detector. Multiple X-ray images are taken as the X-ray source moves relative to the stationary breast specimen. In the preferred embodiment, the X-ray source moves in a range from about 350° to and including about 10°. The source may travel substantially along a path that generally defines an arc, or linearly, while the detector remains stationary throughout and the source remains substantially equidistant from the specimen platform. The set of X-ray image data taken at the different points are combined to form a tomosynthesis image that can be viewed in different formats, alone or as an adjunct to conventional specimen radiography.Type: ApplicationFiled: April 28, 2014Publication date: May 14, 2015Applicant: KUB TECHNOLOGIES, INC.Inventors: Chester LOWE, Vikram BUTANI, Tim ELY
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Patent number: 9029793Abstract: An imaging device (6) for scan-imaging radiation includes an imaging cell array (3) comprising an array of detector cells generating charge in response to incident radiation (1) and an array of pixel circuits each pixel circuit associated with a respective detector cell. The pixel circuit includes circuitry for accumulating plural radiation hit on an associated detector cell and transfer circuitry shifting upon command the accumulated value of all pixels by one step in one dimension (e.g., row by row). The imaged object (2) moves at a speed VOPT (7) with respect to the radiation source and the imaging detector (or source and detector move at ?VOPT with respect to the object) on which the accumulated values are shifted are with VTDI (8). VTDI may equal VOPT in value and direction. Thus, a value is accumulated in a moving information package using multiple pixels (10) and referring directly to a location on the moving object. The accumulated values are read out along one edge of the pixel array.Type: GrantFiled: April 23, 2003Date of Patent: May 12, 2015Assignee: Siemens AktiengesellschaftInventors: Konstantinos Evangelos Spartiotis, Stefan Jurthe, Markku Tapio Eräluoto
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Patent number: 9020094Abstract: A method for assisted positioning of an organ is provided. An acquisition system comprises a platform underneath which a detector is placed for the acquisition of radiographic medical images, during which a radiation source is moved over different successive positions with respect to the detector, wherein at least one medical image is acquired at each position of the radiation source. The method comprises illuminating the platform with a light source of the acquisition system to assist the positioning of the organ on the platform; and determining, with a drive unit of the acquisition system, a positioning limit on the platform based on the distance separating the platform and a compression paddle used to compress the organ and based on the position of the light source relative to the detector, wherein the positioning limit on the platform is a limit beyond which the organ must not lie.Type: GrantFiled: December 22, 2011Date of Patent: April 28, 2015Assignee: General Electric CompanyInventors: Yana Popova, Henri Souchay
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Publication number: 20150110242Abstract: An exemplary apparatus can be provided to determine information regarding a sample(s), which can include, for example an arrangement(s) composed of, at least partially, a particular material in a predetermined area thereof, and including a light facilitating device that can be configured to provide or receive a light radiation(s) to or from the sample(s). The particular material can have a characteristic which can facilitate a sufficient amount of X-ray radiation to pass therethrough so as to generate an X-ray image(s). An X-ray absorption of the material can be at most about 10 times that of a ¼? acrylic plate. The light facilitating device can include a light transmitting configuration which can provide the light radiation(s) to the sample.Type: ApplicationFiled: October 17, 2014Publication date: April 23, 2015Inventors: DAVID BOAS, STEFAN CARP, MARK MARTINO, QIANQIAN FANG
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Patent number: 9008263Abstract: An apparatus and method for imaging a breast are provided. The apparatus includes an X-ray emission unit that emits an X-ray of a first energy spectrum and an X-ray of a second energy spectrum from above a first region of a breast and emits an X-ray of a third energy spectrum from above a second region of the breast different from the first region of the breast; an X-ray detection unit that generates a plurality of image frames related to the breast by detecting the X-rays emitted and passed through the breast; and an image generation unit that generates image data related to the breast by combining the plurality of image frames.Type: GrantFiled: June 27, 2011Date of Patent: April 14, 2015Assignee: Samsung Electronics Co., Ltd.Inventors: Kwang Eun Jang, Jong Ha Lee, Dong Goo Kang, Young Hun Sung
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Patent number: 9001967Abstract: Embodiments of methods and apparatus are disclosed for obtaining a phase-contrast digital radiographic imaging system and methods for same that can include an x-ray source for radiographic imaging; a beam shaping assembly including a collimator and a source grating, an x-ray grating interferometer including a phase grating, and an analyzer grating; and an x-ray detector, where a single arrangement of the beam shaping assembly, the x-ray grating interferometer and a position of the detector is configured to provide spectral information (e.g. at least two images obtained at different relative beam energies).Type: GrantFiled: December 28, 2012Date of Patent: April 7, 2015Assignee: Carestream Health, Inc.Inventors: Pavlo Baturin, Mark E. Shafer
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Patent number: 8995612Abstract: An image diagnosis apparatus and method may emit radiation to a target object, may compress the target object in response to the emitted radiation, and may collect a plurality of images with respect to the compressed target object in response to the emitted radiation. An elastic image with respect to the target object may be generated based on the plurality of collected images.Type: GrantFiled: May 12, 2011Date of Patent: March 31, 2015Assignee: Samsung Electronics Co., Ltd.Inventors: Jong Ha Lee, Dong Goo Kang, Sung Su Kim, Young Hun Sung, Seok Min Han, Kwang Eun Jang
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Patent number: 8976925Abstract: A cone-beam scanning system scans along a half circle. The reconstruction uses a weighting function which decreases for rows farther from the scan plane to take the redundancy of the projection data into account. Another embodiment uses a circle plus sparse helical scan geometry. Image data can be taken in real time.Type: GrantFiled: November 13, 2009Date of Patent: March 10, 2015Assignee: University of RochesterInventors: Ruola Ning, Dong Yang
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Publication number: 20150063528Abstract: Disclosed herein are an X-ray imaging apparatus and a method for controlling the same. The X-ray imaging apparatus includes an X-ray generator configured to radiate first-energy X-rays toward an object, an X-ray detector configured to detect the first-energy X-rays which propagate through the object, an image processor configured to generate a first object image which correspond to the detected first-energy X-rays and to estimate a second object image which corresponds to second-energy X-rays based on the generated first object image, and a controller configured to control the image processor to repeatedly estimate the second object image by controlling the X-ray generator to repeatedly radiate the first-energy X-rays toward the object.Type: ApplicationFiled: August 6, 2014Publication date: March 5, 2015Applicants: SAMSUNG LIFE PUBLIC WELFARE FOUNDATION., SAMSUNG ELECTRONICS CO., LTD.Inventors: Seok Min HAN, Dong Goo KANG, Sung Hoon KANG, Young Hun SUNG, Myung Jin CHUNG
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Publication number: 20150055746Abstract: An X-ray imaging apparatus automatically distinguishes between right and left breasts during mammography. The X-ray imaging apparatus includes: an X-ray assembly configured to press a breast, irradiate X-rays onto the pressed breast, and detect X-rays transmitted through the breast; two handles respectively provided in both sides of the X-ray assembly so that a patient is able to grip the handles, each handle including a sensor for detecting the patient's grip; and a controller configured to determine a position of a handle including the sensor that has detected the patient's grip, and to determine that a breast subject to mammography is a breast corresponding to the determined position.Type: ApplicationFiled: August 6, 2014Publication date: February 26, 2015Applicant: SAMSUNG ELECTRONICS CO., LTD.Inventors: Jong Ha LEE, Young Hun SUNG
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Patent number: 8964936Abstract: System, apparatus and methods specialized for breast and related tissue radiation therapy and imaging of a prone patient but also usable for supine patient if desired or needed. A special treatment radiation source such as a LINAC unit generates radiation of types and energy ranges specifically matched to breast tissue. Any one or more of several imaging technologies may be used to localize the tissue to be irradiated and to generate information for therapy planning, adjustment, and verification.Type: GrantFiled: July 25, 2012Date of Patent: February 24, 2015Assignee: Hologic, Inc.Inventors: Kenneth Brooks, Jay A. Stein, Andrew P. Smith
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Patent number: 8964935Abstract: An apparatus for tomosynthesis and/or mammography includes: an X-ray detector, for receiving and detecting X-rays in a first, detection plane; an X-ray source, which can be activated individually and is positioned to emit a corresponding X-ray beam towards the first, detection plane; a processing and control unit, for activating the X-ray source and receiving a signal relating to X-rays which passed through the breast and were detected by the detector to derive a radiographic image representative of the internal structure of the breast; a grille for removing diffuse radiation, interposed between the source and the detector to receive X-rays which passed through the breast. The grille including plates positioned opposite the chest of the patient when the breast is positioned in a positioning region, and which are angled to converge towards the same region proximal to the X-ray source.Type: GrantFiled: February 21, 2012Date of Patent: February 24, 2015Assignee: I.M.S. Internazionale Medico Scientifica S.r.l.Inventors: Achille Albanese, Bruno Toniolo, Sara Vecchio, Paolo Vignoli, Giovanni Borasi
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Patent number: 8965092Abstract: In a control method and a control unit to control a high-energy, tomosynthesis scan in a contrast agent-assisted dual-energy tomosynthesis, image data of a first tomosynthesis scan are evaluated in order to determine the respective greyscale values for all volume segments. A tube current-time product value for every greyscale value is stored in a memory. For every projection angle, a calculation unit can thereupon calculate a tube current-time product value and acquisition parameters and result with which the second high-energy tomosynthesis scan is controlled.Type: GrantFiled: November 26, 2012Date of Patent: February 24, 2015Assignee: Siemens AktiengesellschaftInventor: Mathias Hoernig
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Patent number: 8958527Abstract: An imaging method performed by a device comprising an X-ray emitting source, a receiver positioned facing the source, and a support on which a subject or organ to be imaged is positioned, the method comprises defining a first set of orientations of the source and a second set of orientations of the source, and acquiring images at the defined orientations of the source, wherein if the first set of orientations comprises an orientation that the second set of orientations does not comprise, only one image is acquired at the orientation, and if both the first set of orientations and the second set of orientations comprise the same orientation, at least two images are acquired at distinct acquisition parameters at the orientation.Type: GrantFiled: February 15, 2012Date of Patent: February 17, 2015Assignee: General Electric CompanyInventors: Serge Muller, Sylvie Puong, Ann-Katherine Carton, Razvan Iordache
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Patent number: 8956045Abstract: A cassette holder of an imaging stand is provided with first and second catch members for catching and holding an electronic cassette from above and below. The first catch member has a multi connector connected to a multi terminal of the electronic cassette. The multi connector is offset with respect to a center line of an imaging surface of the cassette holder. The multi terminal is offset with respect to a center line of an irradiation surface of the electronic cassette in the same direction by the same amount as those of the multi connector. In a state where said electronic cassette mounted on a tray is loaded into the cassette holder, the center line of the irradiation surface coincides with the center line of the imaging surface.Type: GrantFiled: August 30, 2012Date of Patent: February 17, 2015Assignee: FUJIFILM CorporationInventors: Takashi Tajima, Yusuke Kitagawa
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Publication number: 20150043711Abstract: A method to adjust or tune mechanical settings of a mammography apparatus comprising an x-ray source, a paddle and a detector with a detector cover, wherein before executing an x-ray measurement a patient's breast is placed and compressed between the detector cover and the paddle, wherein prior to the x-ray measurement reaction forces between the mammography apparatus and the patient's breast are minimized. The invention relates further to a mammography apparatus comprising an x-ray source, a paddle and a detector with a detector cover, which apparatus is provided with at least one weighing means to measure the downwards forces exerted by (the part of) the apparatus above the weighing means towards the ground.Type: ApplicationFiled: October 27, 2014Publication date: February 12, 2015Inventors: Gerardus Johannes Den Heeten, Cornelis Antonius Grimbergen, Christiaan Neeleman
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Patent number: 8951735Abstract: The invention pertains to certain genetic variants that have been determined to be susceptibility variants of breast cancer. Methods of disease management, including diagnosing increased susceptibility to breast cancer, methods of predicting response to therapy and methods of predicting prognosis using such variants are described. The invention further relates to kits useful in the methods of the invention.Type: GrantFiled: July 3, 2009Date of Patent: February 10, 2015Assignee: deCODE Genetics ehf.Inventors: Simon Stacey, Patrick Sulem
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Publication number: 20150036796Abstract: In a mammography apparatus, a deflection of an x-ray source aligned on a radiation detector is predetermined depending on the size of a breast compressed in the compression unit and/or the density of the breast tissue. Given an increasing deflection on an arc-shaped trajectory of the x-ray source, the compression of the breast is reduced at least once so that the path of the x-rays through the breast stays within a predetermined path length, starting from a first compression in a first x-ray acquisition.Type: ApplicationFiled: August 5, 2014Publication date: February 5, 2015Applicant: SIEMENS AKTIENGESELLSCHAFTInventors: Susanne Dornberger, Thomas Mertelmeier, Ralf Nanke
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Patent number: 8948340Abstract: A mammographic imaging system is optimized for use with a single fixed size flat panel digital image receptor. It accommodates compression devices (paddles) of varying sizes, and positions them properly in a field of view of the image receptor. When a compression paddle with size smaller than the field of view of the image receptor is used, the compression paddle can be shifted laterally in the direction parallel to the chest wall, so as to facilitate different views of different size breasts, and permit the image receptor to image as much of the desired tissue as possible. An automatic X-ray collimator restricts the X-ray illumination of the breast in accordance with the compression paddle size and location in the field of view. An anti-scatter grid, mounted inside the image receptor enclosure, just below the top cover of the enclosure, can be retracted out of the field of view of the image receptor for use in magnification imaging.Type: GrantFiled: October 14, 2013Date of Patent: February 3, 2015Assignee: Hologic, Inc.Inventors: Kenneth DeFreitas, Anthony Pellegrino, Thomas A Farbizio, Roman Janer, Georgia Hitzke
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Publication number: 20150030122Abstract: The invention relates to a method for dual-energy mammography. To enable earlier recognition of the microcalcifications as precursors of an oncological tumor in the breast, the invention provides that a comparison pattern with known distributions for density, thickness and effective atomic number are disposed next to the breast; that based on the comparison pattern, the parameters of the relationship between the atomic number and the difference and ratio of the logarithms of the number of photons that flow through the breast without cooperation at two different radiation energies are determined; and that based on this relationship, the distribution of the atomic numbers in the breast are visually displayed.Type: ApplicationFiled: March 11, 2013Publication date: January 29, 2015Inventors: Viacheslav Gorshkov, Ravil Nazirov, Viacheslav Rodin, Nadezhda Rozhkova, Sergey Prokopenko
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Publication number: 20150030123Abstract: A non-invasive method distinguishes between two types of micro-calcification by x-ray imaging in mammography. Two major types of micro-calcifications are found and confirmed by histopathology and they are correlated to benign and malignant breast lesions. Distinguishing between them non-invasively will significantly improve early breast cancer diagnosis. This is based on the fact that these two types of micro-calcifications show opposite absorption and small-angle scattering signals in x-ray imaging. The imaging system, which can record these two signals of the breast tissue simultaneously for instance, an x-ray grating interferometer, can be used to uniquely determine the micro-calcification type. This is expected to be used in mammography to improve early breast cancer diagnosis, increase diagnosis accuracy and decrease the biopsy rate.Type: ApplicationFiled: February 7, 2013Publication date: January 29, 2015Inventors: Marco Stampanoni, Zhentian Wang
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Patent number: 8942343Abstract: Systems and methods for automatically and dynamically modifying an image acquisition parameter for use in tomosynthesis breast imaging. A selected image acquisition parameter is modified in response to a measured characteristic of an imaged object such as a breast, and thus tailored to provide the highest quality image for the particular object. For example, image quality in a breast tomosynthesis system can be improved by dynamically varying motion and other acquisition parameters of the tomosynthesis system in response to physical characteristics of the breast to be imaged (determined during image acquisition), such as the breast thickness, density or composition.Type: GrantFiled: May 27, 2014Date of Patent: January 27, 2015Assignee: Hologic, Inc.Inventors: Andrew P. Smith, Julian Marshall
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Patent number: 8942342Abstract: The techniques described herein provide a means for generating an x-ray image and ultrasound image depicting parallel planes of an object under examination and may be used in conjunctions with x-ray or ultrasound techniques known to those in the field (e.g., x-ray tomosynthesis, computed tomography ultrasound imaging, etc.). In one example, one or more x-ray images are spatially coincident to one or more ultrasound images and the images may be combined through spatial registration. It finds particular application to mammography examinations but may be used in other fields that use information from multiple modalities.Type: GrantFiled: December 29, 2008Date of Patent: January 27, 2015Assignee: Analogic CorporationInventor: Daniel Abenaim
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Publication number: 20150003579Abstract: An apparatus for imaging a breast using an X-ray includes a support having a through-hole, a holder having a cylindrical shape, disposed in the through-hole of the support, and accommodating a breast of a patient, a linear X-ray generator disposed outside the holder and emitting an X-ray having a linear beam section that is lengthy in a vertical direction of the holder, a linear X-ray detector arranged outside the holder, and a rotation driver rotating the linear X-ray generator and the linear X-ray detector along an outer circumference of the holder.Type: ApplicationFiled: June 26, 2014Publication date: January 1, 2015Applicant: SAMSUNG ELECTRONICS CO., LTD.Inventors: Jong-pil KIM, Woo-sup HAN
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Patent number: 8923477Abstract: A system is described for breast imaging that includes spatially registering sequential mammographic images of the same breast. The system includes a first compression member configured to contact a first side of a breast, a second compression member configured to contact a second side of a breast that is substantially opposite the first side. The system further includes a first image sensor, coupled to the first compression member and configured to detect a position of a first fiducial marker located at the first side of the breast, and a second image sensor, coupled to the second compression member and configured to detect a position of a second fiducial marker located at the second side of the breast.Type: GrantFiled: August 14, 2013Date of Patent: December 30, 2014Assignee: Image Mining, Inc.Inventors: Jack Sklansky, Jeffrey Klein
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Publication number: 20140376691Abstract: In a mammography method and apparatus to generate a tomosynthetic x-ray image of a breast of a patient, two tomosynthesis scans are implemented in chronological succession with x-ray energies that differ from one another. In one of the two tomosynthesis scans a synthetic projection image is generated from at least two projection images acquired in this tomosynthesis scan, this synthetic projection image corresponding to a projection at a projection angle at which a projection image has been acquired in the other tomosynthesis scan. A difference image that is used to reconstruct the tomosynthesis x-ray image is generated from this synthetic projection image and the projection image acquired in the other tomosynthesis scan. Alternatively, in each tomosynthesis scan a respective synthetic projection image is generated from at least two respective projection images acquired in that tomosynthesis scan. Each synthetic projection image represents a projection at the same projection angle.Type: ApplicationFiled: June 19, 2014Publication date: December 25, 2014Applicant: SIEMENS AKTIENGESELLSCHAFTInventor: Mathias Hoernig
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Publication number: 20140348291Abstract: Provided is an X-ray imaging apparatus including an X-ray source to emit an X-ray onto a breast, a detector assembly configured to detect the X-ray transmitted through the breast, a compression paddle configured to compress the breast positioned on the detector assembly, a paddle manipulator configured to control the compression paddle according to a command, a degree-of-compression sensor configured to measure a degree of compression to which the breast is compressed by the compression paddle, and a pressure controller configured to supply a pressure corresponding to the measured degree of compression of the breast to the paddle manipulator.Type: ApplicationFiled: May 23, 2014Publication date: November 27, 2014Applicant: SAMSUNG ELECTRONICS CO., LTD.Inventors: Jong Ha LEE, Young Hun SUNG
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Publication number: 20140341337Abstract: Systems and methods for automatically and dynamically modifying an image acquisition parameter for use in tomosynthesis breast imaging. A selected image acquisition parameter is modified in response to a measured characteristic of an imaged object such as a breast, and thus tailored to provide the highest quality image for the particular object. For example, image quality in a breast tomosynthesis system can be improved by dynamically varying motion and other acquisition parameters of the tomosynthesis system in response to physical characteristics of the breast to be imaged (determined during image acquisition), such as the breast thickness, density or composition.Type: ApplicationFiled: May 27, 2014Publication date: November 20, 2014Applicant: HOLOGIC, INC.Inventors: Andrew P. Smith, Julian Marshall
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Publication number: 20140341336Abstract: An X-ray imaging apparatus and method for controlling the X-ray imaging apparatus are provided. The X-ray imaging apparatus includes an X-ray source configured to generate and emit X-rays onto an object, an X-ray detector configured to detect the X-rays transmitted through the object and convert the X-rays into an electrical signal, a heating portion located at an upper portion of the X-ray detector configured to contact a lower part of the object, a heat transfer portion configured to transfer heat produced in the X-ray source to the heating portion, and a thermal insulation member located between the X-ray detector and the heating portion configured to block heat from being transferred to the X-ray detector.Type: ApplicationFiled: May 20, 2014Publication date: November 20, 2014Applicant: SAMSUNG ELECTRONICS CO., LTD.Inventors: Sung Su KIM, Hyun Hwa OH, Dong Goo KANG, Sung Hoon KANG, Young Hun SUNG, Kang Eui LEE, Seok Min HAN
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Publication number: 20140341338Abstract: Mammography-apparatus for detecting malignant cells in a breast, comprising an x-ray source and an x-ray detector that cooperates with the x-ray source for providing an x-ray image of said breast, and further comprising a paddle for flattening the breast by pressing it against said x-ray detector, and comprising a contact area measuring device for measuring a contact area between the breast and the paddle, wherein the contact area measuring device is embodied with at least a first laminate of an electrically insulating material and an electrically low resistance material, which first laminate is provided on a side of the paddle facing the breast, and wherein the electrically low resistance material is sandwiched between the paddle and the insulating material.Type: ApplicationFiled: July 30, 2014Publication date: November 20, 2014Inventors: Cornelis Antonius Grimbergen, Gerard Johan Den Heeten
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Publication number: 20140334598Abstract: An X-ray imaging apparatus may include a frame, an X-ray generation unit that radiates X-rays onto an object, an X-ray detection unit that detects the X-rays transmitted by the object, and a compression paddle that is combined with the frame so that the compression paddle is placed above the X-ray detection unit and compresses the object. A frame combining unit may form at least one surface of the compression paddle and may be combined with the frame. A plurality of protrusions may be provided at the frame combining unit so that a type of the compression paddle may be recognized, thereby preventing an error in recognizing the type of the compression paddle. Also, the compression paddle may be combined with the frame by using the protrusions to stably combine the compression paddle with the frame.Type: ApplicationFiled: May 7, 2014Publication date: November 13, 2014Applicant: SAMSUNG ELECTRONICS CO., LTD.Inventor: Si Won PARK
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Publication number: 20140328458Abstract: The present invention relates to mammography. In particular, the present invention relates to a method and a corresponding system for individually monitoring a compression force in an apparatus for mammographic examination for personalized compression guidance. In order to provide a personalized guidance for the compression of the breast in a first step (S1a, S1b, S1c) a breast contact area (A) between a breast under examination and a compression plate (3) or a support plate (15) is determined. In a next step (S5) a compression force limit is determined based on the breast contact area (A). Then, in a further step (S9a, S9b, S9c) an output signal (5) representative of the relation between the breast contact area (A) and the compression force limit is provided to a user such that the user may decide whether to complete or to continue the application of compression force.Type: ApplicationFiled: November 14, 2012Publication date: November 6, 2014Inventors: Klaus Erhard, Hanns-Ingo Maack, Andreas Loeprich, Nataly Wieberneit
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Patent number: 8873706Abstract: A radiation imaging apparatus that captures radiographic images includes a radioactive ray generating unit configured to irradiate a subject with a plurality of radioactive rays generated by a plurality of electron sources. A radioactive ray detection unit captures a plurality of first radiographic images based on detection of the plurality of radioactive rays that have passed through the subject at different irradiation angles. Area specification unit specifies an object area using the plurality of first radiographic images captured by the radioactive ray detection unit, and a determination unit determines an electron source to be driven from the plurality of electron sources based on the object area specified by the area specification unit, such that a second radiographic image is captured based on the radioactive rays generated by the electron source determined by the determination unit.Type: GrantFiled: March 2, 2012Date of Patent: October 28, 2014Assignee: Canon Kabushiki KaishaInventors: Takashi Ogura, Osamu Tsujii
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Patent number: 8873716Abstract: An x-ray tube is described that includes components for increasing x-ray image clarity in the presence of a moving x-ray source by modifying focal spot characteristics, including focal spot size and focal spot position. In a first arrangement a static focal spot is moved in a direction contrary to the movement of the x-ray source so that an effective focal spot position is essentially fixed in space relative to one of the imaged object and/or detector during a tomosynthesis exposure. In a second arrangement, the size of the static focal spot is increased, and the resulting increase in tube current reduces the exposure time and concomitant blur effect. The methods may be used alone or in combination; for example an x-ray tube with a larger, moveable static focal spot will result in a system that fully utilizes the x-ray tube generator, provides a high quality image with reduced blur and, due to the decrease in exposure time, may scan the patient more quickly.Type: GrantFiled: May 30, 2013Date of Patent: October 28, 2014Inventors: Baorui Ren, Jay Stein, Zhenxue Jing, Andrew Smith
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Patent number: 8867700Abstract: A method for correcting at least one image of an object obtained with a mammography system is provided. The method comprises: acquiring a pre-exposure image of an object to determine the acquisition conditions for main images, the pre-exposure image comprising regions corresponding to the projection of radio-opaque elements, wherein a mask comprising radio-opaque elements is in an acquisition position; acquiring the main images resulting from the passing through the object of X-rays at higher doses than the dose used for acquisition of the pre-exposure image, wherein the mask comprising radio-opaque elements is in a retracted position; extracting regions from the pre-exposure image which correspond to the projection of radio-opaque elements; and determining the contribution of X-ray scatter at every point of the at least one image of the object, on the basis of the regions extracted from the pre-exposure image.Type: GrantFiled: October 26, 2011Date of Patent: October 21, 2014Assignee: General Electric CompanyInventors: Ann-Katherine Carton, Serge Louis Wilfrid Muller, Remy Andre Klausz, Giovanni John Jacques Palma, Razvan Gabriel Iordache, Sylvie Puong
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Publication number: 20140307848Abstract: According to the present invention, improved methods and apparatus are provided for providing cushioning and other ergonomic surfaces on devices requiring the patient or tissue to be compressed, such as radiography machines, fluoroscopy units, mammography units and the like. In particular a radiolucent pad element is provided for releasable attachment to at least one surface of a compression device to be used under x-ray, for example, during mammography. The pad element of the present invention can be disposable or constructed to be reusable and in some cases may be applied directly to the patient's breast. Furthermore, a cushioned paddle is provided wherein the compression paddle and the cushion can be separately or integrally formed.Type: ApplicationFiled: April 21, 2014Publication date: October 16, 2014Inventors: Gail S. Lebovic, George D. Hermann, David Willis, Thomas A. Howell