Abstract: A method of treating heart failure is disclosed in which, without removing the damaged heart, implantation of prosthetic blood-pumping means within the natural heart sustains its function. The invention includes electrically-powered positive displacement pumps, muscle-powered pumps, and electrically-powered rotary hydrodynamic pumps sufficiently miniaturized and adopted to function within the heart. The invention also includes surgical connectors and surgical methods that permit intraventricular artificial hearts to be effectively applied.

Abstract: A disposable pumping unit has a pump housing which encloses a pumping chamber therein. The pump housing includes an inlet and an outlet communicating with the pumping chamber. A stator is connected to the pump housing and has a distal end which extends into the pumping chamber. The stator defines a central axis. A bearing is supported at the distal end of the stator and is aligned with the central axis. Positioned within the pumping chamber is a rotator supported on the bearing for rotation about the central axis. At least one magnet is carried by the rotator.

Abstract: This invention relates to a method and apparatus for producing fluid pressure from mechanical energy. The apparatus is of the turbomachine type and includes blowers, compressors, pumps, turbines, fluid motors, and the like. This invention also relates to a method of generating pressurized fluid in which the flow of fluid is first deflected by a substantial amount while simultaneously maintaining the relative velocity following said deflection approximately equal to the relative velocity prior to said deflection fluid at least at one location between hub and tip followed by generating pressure by turning back the flow of fluid by an amount approximately equal to the amount of deflection of the fluid while simultaneously decelerating the flow of fluid and keeping the ratio of the axial through flow velocity through the fluid flow path to the outlet velocity following the generation of said deflection equal to approximately 0.66 or less.

Abstract: A temporary circulatory assist pump is disclosed for implantation in the heart of a patient through the femoral artery. The pump is driven by a flexible drive shaft extending through a catheter and being connected to a power source outside the body of the patient. The pump utilizes a helical-shaped foil impeller to pump blood at a rate of approximately three to four liters per minute through the circulatory system of the patient.

Abstract: The reliability and compactness of a percutaneously insertable intravascular axial flow blood pump are improved by connecting the pump's rotor and drive cable through a resiliently extendable rotor extension. The rotor extension and drive cable fitting are so designed that the thrust bearing surfaces of the purge seal and cable fitting can be preloaded by strongly pulling the cable fitting against the resiliency of the rotor extension to move one of the bearings away from the other, then relaxing it to a predetermined preload, and finally immobilizing the bearing in the position corresponding to that preload.

Abstract: A catheter and a method of use for pumping of blood through a living being's vascular system. The catheter has an expandable distal end portion and is introduced into the aorta so that that portion is at a predetermined position spaced from the aortic valve. The catheter comprises an expandable pump and a flexible, skirt-like barrier, both located at the distal end portion. The distal end portion also has an inlet and an outlet. When the catheter is located at the predetermined position its inlet is in fluid communication with the aorta distally of the pump while its outlet is in fluid communication with the aorta proximally of the pump, and the barrier engages the inner periphery of the aorta. Operating the pump causes blood to flow through the aorta, with the barrier ensuring that substantially all of the blood flows into the inlet to the pump means and out the outlet from the pump means and not around the exterior of the distal end portion of the catheter as the pump is operated.

Abstract: An implantable ventricular assist system uses a small high-speed axial flow blood pump which may be grafted into the patient's circulatory system. The pump includes a blood tube in which the pump rotor and stator are coaxially contained, and a motor stator surrounding the blood duct. A permanent magnet motor rotor is integral with the pump rotor. Purge fluid for the hydrodynamic bearings of the device and power for the motor are preferably percutaneously introduced from extracorporeal sources worn by the patient. The purge fluid is introduced into the pump stator blades. This construction avoids the creation of discontinuities in the blood path wall due to the routing of drive power and/or fluid supply elements through the blood path wall. The described construction greatly reduces the size of the implant needed for a given blood flow rate and enhances its physiological compatibility with the body.

Abstract: A disposble centrifugal pump has two parts. One part includes a blood pumping chamber and a driven impeller, while the second part includes an impeller drive to which the impeller is coupled by mechanical shaft couplings. Two seals are provided to limit exposure of the fluid being pumped to possible contaminants. The first seal provides an effective shaft seal around the impeller shaft as it leaves the pumping chamber. The second seal provides an effective seal about all outer portions of the shaft when the shaft is coupled to the impeller drive to limit migration of possible contaminants along the shaft and into the pumping chamber.

Abstract: A disposable, sterilizable cable drive unit for an intravascular blood pump includes a rotor enclosed in a fluid-tight enclosure which can be slipped into the stator of a drive motor. The unit is connectable to a constant-rate purge fluid supply and to a dual-lumen cable sheath. One lumen provides a sterile purge fluid path; the other carries the drive cable to the blood pump and provides a return path for a flushing fluid in which the cable is immersed. The flushing unit is derived from the purge fluid supply at a constant rate, and the rotor may also be immersed in it if desired. The unit is held in the drive motor by a manually operated detent, and the self-centering action of the rotor aligns it with the stator when the motor is energized. The motor is mounted on a gimbal so as to be alignable with the cable sheath at its point of insertion into the patient's vascular system, in order to prevent stresses on the patient and kinks in the cable sheath.

Abstract: A miniature high-speed intravascular blood pump is formed as a single stage with two rows of rotor blades and a single row of stator blades within a tubular housing. The rotor's first row produces a mixed centrifugal and axial flow, while the rotor's second row produces a purely axial flow. The blades of the second row are shaped so as to produce a uniform blood flow along the trailing edges of the blades. For this purpose, the bases of the outer trailing edges of the second row blades have a negative propulsion angle. The pump has a purge-sealed hydrostatic bearing which is spring-loaded for minimum gap. The pump is driven by a cable encased in a dual-lumen, fluid-filled cable sheath formed of a coextrusion of a soft, blood-compatible outer layer and a stiff, abrasion-resistant inner layer. The cable sheath serves both as a purge fluid supply for the bearing, and as a means for flushing abraded debris away from the pump.