Abstract: A concentrated salicylic acid gel comprising salicylic acid and a stabilizer compound, wherein the salicylic acid comprises at least 30 wt % of the total weight of the gel.

Abstract: Provided is a method for producing a coating film formed on the skin by electrostatic spraying, the coating film having good feeling and not causing damage on the coating film even after a lapse of a long time A method for producing a coating film on the skin, comprising the steps of: A) electrostatically spraying a composition X comprising a component (a) and a component (b) directly onto the skin to form a coating film on a surface of the skin: (a) one or more volatile substances selected from the group consisting of water, an alcohol and a ketone; (b) a polymer capable of forming a coating film; and B) applying a composition Y other than the composition X, comprising a component (c) and a component (d) to the skin in the order presented or in reverse order: (c) 0.5% by mass or more and less than 5% by mass of an adhesive polymer; (d) one or more selected from the group consisting of a polyol and a liquid oil.

Abstract: A solid W/O stable composition comprising a gellifying system comprising at least one hydrophobic gelling agent and at least one hydrophilic gelling agent and an emulsifying system comprising at least one surfactant having HLB value of 14 or less. Further there is disclosed a method of treatment keratinous surface with the inventive composition.

Abstract: Giant multi-lamellar vesicles (GMVs) comprising lecithin are provided which are at least about 3 ?m in size. Methods for preparing the GMVs, and for preparing large unilamellar vesicles (LUVs) from the GMVs, are provided, as well as methods for encapsulating cargo within the GMVs and LUVs. The present vesicles are useful for the oral delivery of encapsulated cargo.

Abstract: Multi-layer microcapsules comprising a core comprising one or more active agents and two or more shells comprised of a wall-forming polymeric material, an opaque substance and a fatty acid salt, which are rupturable upon rubbing or pressing on the skin, are disclosed. The microcapsules are characterized by improved lightness values (L*) and/or compatibility in aqueous solution-containing formulations. Cosmetic or cosmeceutic formulations comprising the microcapsules, which can be, for example, body skin care formulation or facial skin care formulations, are also provided.

Abstract: A cosmetic composition including: (A) a silicone film-forming agent, and (B) an organopolysiloxane having a polyalkylene oxide moiety and a cationic group other than the component (A), wherein the content of water is 50% by mass or less. The cosmetic composition is a hair cosmetic composition or a hair dye composition.

Abstract: A composition includes polydatin and at least one photoisomerization stabilizer and cosmetically acceptable carrier. The at least one photoisomerization stabilizer confers photostabilization to trans-polydatin by at least about 5%, relative to an otherwise identical composition without the at least one photoisomerization stabilizer.

Abstract: The invention relates to a process for coating a solid, water-insoluble particulate matter, with a metal oxide comprising: (a) contacting the solid, water-insoluble particulate matter with an ionic additive and an aqueous medium to obtain a dispersion of said particulate matter having positive charges on its surface; (b) subjecting the particulate matter to a coating procedure comprising precipitating a metal oxide salt onto the surface of the particulate matter to form a metal oxide layer thereon to thereby obtain particulate matter coated by a metal oxide coating layer; (c) repeating step (b) at least 4 more times; and (d) aging said coating layer. The invention further relates to particles comprising a particulate matter coated by a metal oxide layer, to a use of the particles for topical administration, and to a method for preventing, reducing, or eliminating pests at a locus, using the particles.

Abstract: Topical formulations comprising soft glycopyrrolates are useful for treating excessive sweating conditions in subjects, such as humans suffering from hyperhidrosis. Preferably, at least one soft anticholinergic agent is provided in an effective amount or concentration in an anhydrous formulation that can inhibit excessive perspiration resulting from a condition such as hyperhidrosis.

Abstract: The present invention provides a topical composition for a nanobubble cosmetic with which functional properties required by various types of cosmetic products can be improved. The present invention is a topical composition for a nanobubble cosmetic to be used in a container equipped with a device mechanism for generating nanobubbles, the topical composition containing a polyoxypropylene diglyceryl ether and ethoxydiglycol, or containing hyaluronic acid or a salt thereof, or containing ethanol and menthol or a derivative thereof, or containing sorbitol and glycerin, or containing phytosteryl/octyldodecyl lauroyl glutamate, or containing glycereth-26, or containing hydrogenated lecithin and polysorbate 20, or containing ethanol and polysorbate 20.

Abstract: Cosmetic compositions, including hair coloring compositions, comprising graphene oxide (GO), reduced graphene oxide (r-GO), or both, and water are provided.

Abstract: Disclosed is a method of improving the appearance of skin with a low-pH skin care composition that contains hydroxycinnamic acid (HCA) and a vitamin B3 compound in a synergistic combination.

Abstract: The present application is directed to stabilized core-shell microcapsules comprising a core of benzoyl peroxide (BPO) or all trans retinoic acid (ATRA) and a metal-oxide shell; and to pharmaceutical compositions and methods of use thereof.

Abstract: A cleansing composition comprising a detersive surfactant; an aqueous carrier; from about 0.5% to about 30% by weight of the cleansing composition of discrete particles comprising anhydrous particles and an aqueous phase, and wherein said anhydrous particles comprise: one or more fatty amphiphile selected from the group consisting of fatty alcohol, fatty ester, fatty acid, fatty amide and mixtures thereof; of one or more secondary surfactants selected from the group consisting of anionic, nonionic, zwitterionic, cationic or mixtures thereof. Wherein the discrete particle of the cleansing composition has a size from about 500 microns to about 7000 microns, and wherein the cleansing composition has a % transmittance of about 75% or higher.

Abstract: A composition containing at least 75% by weight of water, relative to the total weight of the composition, hydroxylated diphenylmethane derivative(s), oil(s) containing in its structure at least one amide unit, and crosslinked copolymer(s) containing at least one unit of an unsaturated olefinic carboxylic acid and at least one unit of a (C10-C30)alkyl ester of unsaturated carboxylic acid.

Abstract: The disclosure discloses a Pickering emulsion stabilized by cellulose from ginkgo seed shells and a preparation method thereof, and belongs to the fields of preparation methods of biomass materials and food chemical industry. The disclosure uses ginkgo seed shells as a raw material to obtain high-purity cellulose through hot alkali treatment and sodium chlorite bleaching. After the cellulose is dried, the cellulose is hydrolyzed with sulfuric acid to obtain a cellulose nanocrystal suspension. The suspension is mixed with an oil phase, and the Pickering emulsion is obtained through high-speed shearing and homogeneous emulsification. The disclosure can prepare cellulose nanocrystals with different aspect ratios by adjusting the parameters of high-speed shearing and homogeneous emulsification according to actual production needs.

Abstract: This invention relates to oral care compositions comprising a basic amino acid or salt thereof, a zinc source, and a preservative, as well as to methods of using and of making these compositions.

Abstract: Cosmetic and/or pharmaceutical compositions for promoting hair growth by modulating the expression of genes involved in the JAK-STAT signaling pathway are provided. The compositions include at least one plant lipid, preferably pataua (Oenocarpus bataua) oil. Also included are methods for promoting hair growth by modulating the expression of genes involved in the JAK-STAT signaling pathway.

Abstract: An oil-in-water emulsified cosmetic comprising an aqueous medium, an alkali-soluble polymer having a carboxy group and an amphiphilic side chain comprising a hydrophobic block and a hydrophilic block and bonded to the main chain at the hydrophilic block end, a nonionic surfactant having a C3-C6 straight-chain or cyclic polyol residue and an HLB of (6.0-12.0), a liquid oil and a paste oil.

Abstract: Disclosed is a skin care product formulation development method and system. The method comprises: acquiring names and weights of new ingredients, searching formulations containing at least one of the new ingredients in a skin care product formulation database, and obtaining a plurality of candidate formulations; deleting the new ingredients contained in each of the candidate formulations to obtain a plurality of supplement formulations; clustering the plurality of supplement formulations based on ingredient correlations to obtain a plurality of cluster groups; calculating a correlation score of each cluster group to the deleted new ingredients respectively; and determining the cluster group with the highest correlation score, and generating a new skin care product formulation based on the cluster group with the highest correlation score.

Abstract: Composition in the form of an oil-in-water emulsion that includes at least 1% of an oil phase, and an aqueous phase. The composition includes 0.1 to 15 wt % spiculisporic acid relative to the total weight of the composition, at least one base selected from amino acids and alkanolamines in an amount suitable for forming at least a monosalt of spiculisporic acid, less than 3% glycol(s) and/or polyol(s) relative to the total weight of the composition, at least one UV filter and/or an additive selected from volatile aromatic materials such as essential oils and fragrance substances, fillers, dyeing materials such as pigments, mother-of-pearl or particles with a metallic sheen, moisturizers, anti-wrinkle or anti-age agents, peeling agents, antioxidants, active ingredients stimulating the synthesis of epidermal and/or dermal macromolecules, dermo-relaxing agents, depigmentation agents, deodorant agents and mixtures thereof.

Abstract: The invention is directed to a composition suitable for topical application that comprises a naturally derived preservative having benzoic acid or a derivative thereof. The composition is stable when preserved with the naturally derived preservative and when at a pH that is above the natural pH of skin to as high as 7.25.

Abstract: Provided is a collection of polymer particles comprising (I) a plurality of acrylic particles (I) each comprising (a) an acrylic core polymer (Ia) comprising (i) polymerized units of one or more monovinyl acrylic monomers (Iai), (ii) polymerized units of one or more Si-free graftlinkers (Iaii), (b) a shell polymer (Ib), (II) a plurality of hybrid polymer particles (II), each comprising (a) a core polymer (IIa) comprising (i) polymerized units of one or more silicon-containing monomers (IIai); (ii) optionally, polymerized units of one or more monovinyl acrylic monomers (IIaii); and (iii) polymerized units of one or more Si-free graftlinkers (IIaiii); (b) a shell polymer (IIb) comprising polymerized units of one or more acrylic monomers (IIb).

Abstract: An oil-in-water emulsion composition for skin includes 0.2 to 2.5% by mass of polyisobutene having a relative mass in a range of 30,000 to 100,000. The composition is applied to skin except for a lip.

Abstract: A method for topically treating skin is disclosed. The method can include applying to skin a composition that includes tetrahexyldecyl ascorbate, Morus alba fruit extract, Acmella oleracea extract, and retinol, wherein topical application of the composition treats the skin.

Abstract: The present disclosure relates to compositions for topical application, where the compositions comprise microcapsules having a core that comprises benzoyl peroxide and a shell that comprises an inorganic polymer, microcapsules having a core that comprises a retinoid and a shell that comprises an inorganic polymer, and a stabilizing agent. The composition can be in a variety of forms, such as emulsion and gel.

Abstract: Disclosed is a detergent composition (F) for domestic or industrial use including, as thickener, a self-invertible inverse latex including an aqueous phase including: a) a crosslinked anionic polyelectrolyte (P) consisting of: —at least one monomer unit derived from at least one monomer chosen from the elements of the group consisting of acrylic acid, methacrylic acid, 2-carboxyethylacrylic acid, itaconic acid, maleic acid, 3-methyl-3-[(1-oxo-2-propenyl)amino]butanoic acid, the carboxylic function of the monomers being in free acid, partially salified or totally salified form; and—at least one monomer unit derived from a polyethylenic crosslinking monomer (AR), b) ethylenediaminedisuccinic acid in trisodium salt form.

Abstract: The salt-stable cosmetic composition is in the form of a low viscosity emulsion (oil in water) and is especially stable at high electrolyte contents and includes a salt-stable polymeric system comprising a polymer blend such that the salt-stable cosmetic composition resists phase separation, pilling and gellifying at high salt content, conferring a flowable, lightweight lotion-type texture.

Abstract: A gelled composition includes at least 50% by weight of at least one hydrocarbon oil that includes a content by weight of isoparaffins ranging from 90 to 100%, a content by weight of normal paraffins ranging from 0 to 10% and a content of carbon of biological origin greater than or equal to 90% relative to the total weight of the hydrocarbon oil, and at least 1% by weight of at least one gelling agent chosen from among: polymers chosen from homopolymers and copolymers obtained from at least one monomer chosen from among isoprene, butadiene, styrene and (meth)acrylates, and the mixtures of same, and non-polymer gelling agents, relative to the total weight of the gelled composition.

Abstract: The invention relates to high polyol compositions comprising foaming, preferably mild surfactants. While xanthan gum is normally incompatible with such composition, applicants have surprisingly found compositions (having specified particles size) and process for making such compositions such that xanthan gum can now be used as structurant.

Abstract: The present disclosure provides fragrance compositions having an olfactive profile that changes with time. The fragrance compositions include at least two contrasting perfume accords. The at least two contrasting perfume accords provide an olfactory modulating effect, such that the fragrance compositions deliver a desirable scent with increased perceived intensity and improved longevity of perception.

Abstract: The present invention provides resin beads that can provide various types of products such as cosmetics which are unlikely to generate an odor and have superior tactile impression and spreadability on the skin and that can be substituted for resin particles composed of a synthetic material derived from petroleum, and the present invention also provides various types of products such as cosmetics using the resin beads. The resin beads are formed with a resin containing a cellulose derivative as a main component. In the resin beads, the cellulose derivative is at least one selected from the group consisting of cellulose acetate, cellulose acetate propionate, ethyl cellulose, and hydroxypropyl methyl cellulose, the volume average particle diameter is 50 ?m or smaller, the degree of sphericity is 0.7 to 1.0, the degree of surface smoothness is 80 to 100%, the acetyl group content ratio is 15% by mass or less, and the propionyl group content ratio is 10% by mass or more.

Abstract: The present disclosure relates to stable aqueous compositions of alkyl sulfates, which are suitable for numerous commercial applications due to their favorable cleaning and foaming properties. More particularly, the disclosure relates to stable aqueous compositions of alkyl sulfates in combination with select hydrophobic agents, such as essential oils.

Abstract: The present invention belongs to the cosmetic field.

Abstract: A no-sting skin protectant film forming composition is formulated with a film forming polymer having both polar and nonpolar characteristics, a no-sting nonpolar solvent system, and at least one skin health ingredient. The no-sting skin protectant film forming composition is configured to form a protective film on a skin surface after the solvent system evaporates.

Abstract: An all-natural, moisturizing soap composition that allows for high vegetable butter fat content while also being capable of processing for high quality bar soap (moisturizing properties without sticky pellets, brittleness, cracking, and/or inhibition of lather formation) and a method for making the same and other soaps is provided. The soap composition may contain up to 50% vegetable butter fat(s). The semi-continuous process for saponification provides a fast and energy efficient alternative to prior art methods, while also allowing for high quality bar soap that contains a high content (up to 50%) of vegetable butter fat(s).

Abstract: The present disclosure relates to, inter alia, a gel formulation in a package, the package may be pressurized. The formulation comprises one or more active agents and is co-mingled with a gas propellant prior to being filled under pressure into the package. The gas propellant is added in sufficient amounts to be dispersed in the formulation; the pressurized package is under sufficient pressure suitable to maintain the first gas propellant dispersed in the formulation. The pressurized package is under sufficient pressure to expel the formulation as a whipped gel formulation upon application of external force on the formulation in the package. The present disclosure also relates to, inter alia, a method of preparing the disclosed formulation; a package comprising the disclosed formulation, and a method of using the disclosed formulation.

Abstract: The present invention relates to a composition for inhibiting PAR2 activity including punicalagin, and more specifically, the present invention provides a composition for inhibiting PAR2 activity including punicalagin, a stereoisomer thereof, or a pharmaceutically acceptable salt thereof, or a pharmaceutical composition, health functional food composition, or cosmetic composition for preventing or treating an inflammatory disease or pruritis.

Abstract: The present invention relates in general to a hand-held hair removal article. More specifically, the invention relates to a shaped flexible article adapted to scoop a hair removal compound, apply the hair removal compound to a hair removal area, and remove the hair removal compound and hair from the hair removal area.

Abstract: The present invention relates to compositions and methods for reducing or eliminating wrinkles and improving skin texture and appearance. The compositions, which comprise at least one acetyl hexapeptide and a dipeptide that is optionally complexed to an amino acid, may be administered orally, sublingually, topically and/or transdermally.

Abstract: A method for insertion, maintenance, and removal of urethral catheters in mammals including humans includes steps for preventing or reducing the incidence of catheter associated urinary tract infections. In addition to sterile procedures currently practiced or as may be practiced in the future in connection with catheter use, the method includes the steps of applying an antiseptic, zwitterionic, and acidic skincare solution capable of preserving the stratum corneum to the perineum, meatus, and contiguous mucosa surrounding the insertion site before insertion, after insertion, periodically during the period of indwelling, in connection with any incidence of incontinence, and, optionally, before and after removal of the catheter. Application of the solution optionally is continued after catheter removal on a periodic basis until the threat of an infection associated with catheter use has passed, typically at least about five (5) to seven (7) days and up to thirty (30) days.

Abstract: Core-shell particles have a hydrophobic core and a shell formed of o containing hyperbranched polymers (HP). The HP can be covalently bound to the one or more materials that form the core or coated thereon. The HP coating can be modified to adjust the properties of the particles. For example, unmodified HP coatings resist non-specific protein absorption. Alternatively, the hydroxyl groups on the HP coating can be chemically modified to form functional groups that react with functional groups on tissue to adhere the particles to the tissue, cells, or extracellular materials, such as proteins. Such functional groups include, but not limited to, aldehydes, amines, and O-substituted oximes. Topical formulation for application to the skin contain these HP coated nanoparticles. In some embodiments, the particles include cosmetic, therapeutic, diagnostic, nutraceutical, and/or prophylactic agents, such as those used as sunblock compositions.

Abstract: A slurry analysis system (14) for estimating a first characteristic of a slurry (12) having a plurality of particles (18) suspended in a dispersion medium (20) can include a slurry filter (40) that filters the slurry (12); and a control system (26) that estimates the first characteristic of the slurry (12) using a flow rate of a filtrate (50) through the slurry filter (40) and a slurry filtration pressure of the slurry (12).

Abstract: A fabric care composition including a plurality of particles, wherein each of the particles include a fabric care agent, water, a sugar alcohol polyol, and a modified starch. The modified starch can have a dextrose equivalent from 4 to 20. The fabric care active agent, said water, and said sugar alcohol polyol are dispersed in the modified starch.

Abstract: Described herein are nasal pharmaceutical compositions comprising a porous excipient and an active agent, wherein the active agent is loaded onto a surface of the porous excipient located inside pores of the porous excipient, and wherein the composition is adapted for nasal administration. Also described herein are methods of making and using nasal pharmaceutical compositions.

Abstract: A composition is provided for hard surface cleaning and odor removal. Performance characteristics such as high odor removal and hard surface cleaning performance are achieved using a zinc ricinoleate-based odor neutralizer coupled with a polymeric ester based hard surface cleaning agent. The composition may be formulated for use in a trigger bottle, aerosol, or wipe applications.

Abstract: Methods for the production of L-glufosinate (also known as phosphinothricin or (S)-2-amino-4-(hydroxy(methyl)phosphonoyl)butanoic acid) are provided. The methods comprise a two-step process. The first step involves the oxidative deamination of D-glufosinate to PPO (2-oxo-4-(hydroxy(methyl)phosphinoyl)butyric acid). The second step involves the specific amination of PPO to L-glufosinate, using an amine group from one or more amine donors. By combining these two reactions, the proportion of L-glufosinate in a mixture of L-glufosinate and D-glufosinate can be substantially increased.

Abstract: Disclosed is a composition for improving stress tolerance of plants including at least one hydroxycinnamic derivative oligomer, and optionally a water-solubilizing agent. Also disclosed is a method for improving stress tolerance of a plant including applying such composition on the plant.

Abstract: To develop a novel administration method of a fucoidan-containing hair-growing agent and to provide a means for exerting excellent effects of a fucoidan. A hair-growing agent of the present invention is characterized in that it is composed of a combination of a fucoidan-containing microneedle and a fucoidan-containing liniment. A base of the fucoidan-containing microneedle is preferably a biosoluble polymer. A hair-growing method of the present invention is characterized in that the fucoidan-containing microneedle and the fucoidan-containing liniment are concomitantly used.

Abstract: The present invention generally relates to uses of glial cell line-derived growth factor (GDNF) in cutaneous wound healing and hair growth. Methods of effecting hair growth and/or wound healing which feature administration of GDNF, or a biologically active fragment thereof, to subjects, e.g., human subject, are disclosed herein. The invention relates also to formulations and kits for achieving the indicated pharmaceutical advantages.