Abstract: The present invention relates to methods for preparing compositions comprising calcium and fluoride, and, in particular, to methods for preparing compositions comprising calcium that is stabilised with a stabilising agent and fluoride. For example, the method is for the preparation of compositions comprising amorphous calcium phosphate stabilised by phosphopeptides, and free fluoride. The invention also extends to various compositions produced by such methods, including oral care products.

Abstract: The present invention discloses an oral care composition for the prevention or minimization of stain formation on a tooth surface as well as an oral care composition for prevention or reduction of existing stains from, a tooth surface.

Abstract: A dentifrice composition is described comprising a source of free fluoride ions; and from 0.1% to less than 0.5% by weight of the composition of a copolymer of methyl vinyl ether with maleic anhydride or acid; and wherein the composition has a slurry pH from 6.0 to 7.5, and wherein the composition is free of a carboxylic acid or alkali metal salt thereof wherein the acid is selected from the group consisting of malonic acid, glutaric acid, tartaric acid, lactic acid and mixtures thereof. The composition enhances fluoride uptake into teeth and provides protection against acidic challenges.

Abstract: Provided are methods of providing a benefit to the oral cavity by administering to the oral cavity a poorly-soluble calcium compound and subsequently introducing fluoride to the oral cavity.

Abstract: A tooth paste composition comprising black cumin oil (Nigella sativa) and fluoride-doped bioactive glass, zinc oxide, and/or titanium oxide is disclosed.

Abstract: An dual oral composition is provided having a first peroxide-containing component and a second bicarbonate-containing component having exceptional anti-plaque and antibacterial action with re-mineralization properties.

Abstract: Disclosed herein are oral care compositions comprising at least one phosphate/acrylate copolymer, at least one cationic antibacterial agent, at least one synthetic anionic linear polycarboxylate polymer, at least one surfactant, and zinc lactate. Also disclosed herein are methods for the treatment and/or inhibition of gum disease or halitosis comprising contacting the oral cavity with the oral care compositions disclosed herein, as well as methods of making the oral care compositions disclose herein.

Abstract: This invention relates to oral care compositions comprising an effective amount of a basic amino acid in free or salt form, together with an antibacterial agent, and to methods of using and of making such compositions.

Abstract: The invention includes a toothpaste or other orally applied product to be used at least once daily to help prevent or inhibit the acquisition of a number of infections by oral or pharyngeal tissues, particularly including the “common” cold. These compositions possess a combination of ingredients that is not found in other toothpastes or other orally applied products, and these ingredients work together to synergistically interfere with the acquisition of a number of pathogens. The toothpastes will have the usual dentifrice ingredients known to prevent tooth decay, as well as those that reduce halitosis (i.e., bad breath), and prevent gingivitis. In addition, the toothpastes will include one or more of: 1) GALALCOOL® as an individual compound, and not as an extract component; 2) zinc protoporphyrin IX; and 3) one or more other colorless or low-color tannin(s) each as an individual compound, and not as an extract component.

Abstract: An oral composition for treating diseases in the mouth caused by formulation of biofilms on teeth. The oral composition includes water, stannous ion source, casein phosphopeptide-amorphous calcium phosphate, and at least citric acid or a citric acid salt.

Abstract: Disclosed are therapeutic oral compositions useful in the treatment of a variety of oral disorders, in which the composition can provide blockage of dentinal tubes, while at the same time provide antibacterial and anti-caries efficacy. The compositions include arginine in free or salt form, a mucoadhesive polymer, and at least one component selected from pyrophosphates, zinc salts, potassium salts, strontium salts, and mixtures thereof.

Abstract: The disclosure describes compositions for dental varnishes, methods of making the compositions, and methods of using the compositions, such as in the treatment and prevention of hypersensitivity in teeth.

Abstract: A dentifrice composition having a low water phase comprising effective amounts of polyphosphate and ionic active ingredients.

Abstract: Disclosed herein are striped dentifrice compositions stable to color bleeding comprising at least one zinc ion source and a thickening system comprising xanthan gum present in the composition in an amount ranging from about 0.3% to about 1% by weight and carboxymethyl cellulose present in the composition in an amount ranging from about 1% to about 2% by weight. Further disclosed herein are methods for cleaning the surface of a tooth comprising applying the striped dentifrice compositions stable to color bleeding as disclosed herein.

Abstract: Film forming compositions and methods for preventing stains and increasing shine and gloss of teeth. The film forming compositions may include a polymer, such as a hydrophobic polymer, and an orally acceptable solvent. The hydrophobic polymer may include an acrylate component and a hydrophobic group coupled with one another. The hydrophobic group may include an alkyl chain, a polyethylene glycol, a polypropylene, a polyester, a polyorthoester, a phospholipid, a long chain fatty acid, a vinyl chloride, fluorethylene, a siloxane, a urethane, an octylacrylamide, a butylaminoethyl, a styrene, and combinations thereof.

Abstract: An oral care composition comprising zinc phosphate, stannous fluoride, an anionic polymer, and a basic amino acid, as well as methods of using the same.

Abstract: Disclosed is a method, and a system, for accomplishing the in situ formation of a gel in an interdental space. This is useful for the interdental application of one or more dental care agents, such as antimicrobial agents or other anti-plaque agents. The invention makes use of a two component system comprising a gelable liquid and a liquid gelling agent capable of bringing about gelation of the liquid. The system of the invention is arranged such that first the gelable, typically viscous, liquid can be applied, and then the liquid gelling agent is forced, e.g. jetted, into the applied gelable liquid. The system is designed such as to prevent the gelling agent and the gelable liquid to come into contact with each other before both have been applied. The system is configured to allow the gelable liquid to be applied prior to the gelling agent.

Abstract: Provided herein are stable lisinopril oral liquid formulations. Also provided herein are methods of using lisinopril oral liquid formulations for the treatment of certain diseases including hypertension, heart failure and acute myocardial infarction.

Abstract: Film forming compositions and methods for occluding dentin tubules of teeth to treat dentinal hypersensitivity of the teeth are provided. The film forming compositions may include a hydrophobic copolymer, a rosin, and an orally acceptable solvent. The hydrophobic copolymer may include an acrylate/octylacrylamide copolymer, such as 2-propenoic acid, 2-methyl-, 2-methylpropyl ester, polymer with 2-propenoic acid and N-(1,1,3,3-tetramethylbutyl)-2-propenamide. Methods for treating dentinal hypersensitivity may include contacting the film forming composition with surfaces of the teeth.

Abstract: To obtain an inorganic blue fluorescent material that is composed of elements for which there are no suspected harmful effects on humans, and that has excellent texture when applied to skin. A fluorescent material for a cosmetic being a composite oxide containing from 0.0005 to 0.05 (in terms of a mole ratio relative to 1 mol of phosphorous in a molecule) of Ce in a compound represented by general formula CaaPbOc (3.2?a?5.0, b=2, c=a+5) and having an average particle diameter of from 1 to 10 ?m.

Abstract: A film forming composition and methods for preventing acid erosion of teeth and preventing the formation of caries on teeth are disclosed. The film forming composition may include a hydrophobic copolymer, a fluoride compound, and an orally acceptable solvent. The film forming composition may also include a cellulose derivative, a rosin, a fluoride compound, and an orally acceptable solvent.

Abstract: A smoking article includes a smokable material and a filter downstream of the smokable material. The filter comprises a capsule having a core and a breakable shell. The core has a mixture including one or more lipid compounds and one or more humectants. The lipid compounds account for 50% or more of the weight of the mixture. At least one of the one or more humectants is capable of interacting with one or more smoke constituents to reduce the concentration of the one or more smoke constituents in mainstream smoke.

Abstract: A dentifrice composition with tin, calcium, and a pH of greater than 7. A dentifrice composition with tin, fluoride, calcium abrasive, water, and a pH of greater than 7. Dentifrice compositions with a high tin ion availability. Dentifrice compositions comprising stannous fluoride and/or stannous chloride in combination with calcium carbonate.

Abstract: An oral care composition and method are described in which the composition is free of an anionic surfactant and a fluoride source.

Abstract: Oral care compositions comprising an acidic amino acid and stannous ion source are provided for promoting Gum Health of a user.

Abstract: A formulation includes a cannabinoid extract that is pharmaceutically effective by systemic delivery via a recipient's oral mucosal lining. The method of delivery avoids the digestive tract processing and liver metabolizing of the active ingredients of the formulation, whereby lower doses cause a desired therapeutic effect or other intended effect. Variations of the formulation include a cannabinoid extract and one or more of pregelatinized tapioca starch polymethylsilsesquioxane, bromelain, volume Fenugreek gum, vitamin B12, luo han guo fruit extract, mannitol, microcrystalline cellulose, sodium alginate, gellan gum, menthol Natural peppermint flavor or oil, Grapefruit flavored powder or oil, magnesium stearate and/or citric acid. The cannabinoid extract may include Tetrahydrocannabinol, tetrahydrocannabinolic acid, Cannabidiol, Cannabidiol acid, and/or other cannabinoid sourced from a Cannabis sativa plant.

Abstract: Provided are aqueous soluble tin phosphate complexes formed from a mixture comprising tin (II) fluoride or tin (II) chloride and a tripolyphosphate salt, e.g., sodium tripolyphosphate (Na5P3O10), and oral care compositions comprising the complex and uses thereof.

Abstract: Provided herein are methods of treating one or more symptoms of a gastric disorder in the oral cavity of a subject in need thereof, wherein the method comprises applying to the subject's teeth an oral care composition comprising a basic amino acid in free or salt form, wherein the basic amino acid is arginine (e.g., free form arginine); zinc oxide and zinc citrate; and an orally acceptable carrier.

Abstract: A tooth whitening composition includes a hydrophobic copolymer, a hydrophilic whitening agent and a polar solvent.

Abstract: An oral care composition including an orally acceptable vehicle is disclosed. The orally acceptable vehicle includes a source of hydrogen peroxide, an acyl donor, and an enzyme that catalyzes the generation of peracetic acid between the source of hydrogen peroxide and the acyl donor.

Abstract: An oral care composition is disclosed. The composition comprises zinc phosphate and a silicate compound comprising a metallic element that in cationic form is capable of reducing tooth enamel erosion. The zinc phosphate is added to the oral care composition as a preformed salt. Methods of administering the oral care compositions to subjects in need thereof are also disclosed.

Abstract: Disclosed herein is a method for preparing hydroxyapatite structures from natural sources such as mammalian teeth and bones. The method may include obtaining a raw powder by grinding raw materials, obtaining a first mixture by mixing the raw powder with one of an alkali metal carbonate and an alkaline earth metal carbonate, and heating the first mixture at a first predetermined temperature for a first predetermined period.

Abstract: Anhydrous oral care compositions and methods for making and using the same are described herein. The anhydrous oral care compositions may include an orally acceptable vehicle, a peroxide whitening agent, and an abrasive system. The abrasive system may include at least one abrasive having a pellicle cleaning ratio (PCR) greater than or equal to 100.

Abstract: The present invention provides a preparation for attaching to teeth or tooth peripheries. The preparation for attaching to teeth or tooth peripheries of the present invention can give high adhesive force to the desired site despite interproximal space or curves of teeth. It is easy to hand while controlling drug release.

Abstract: The disclosure contains a method of quantifying and/or evaluating metal ions in a dentifrice, wherein the method comprises subjecting the dentifrice to X-ray absorption spectroscopy (XAS), and wherein the XAS is used to measure and/or evaluate the metal ions in the dentifrice. Also disclosed are methods of selecting and screening for dentifrices based upon the evaluation and quantification of their metal ion content.

Abstract: A method and apparatus, for treating plaque and calculus in the mouth cavity—particularly on teeth—are disclosed. The apparatus—and accordingly the method—is comprised of introducing at least one first-component comprising a material with a redox potential for preventing anions precipitation; and introducing at least one second-component comprising a material with a redox potential for preventing cations precipitation.

Abstract: The present invention includes an antimicrobial composition comprising a safe and effective amount of a surfactant, e.g., sodium dodecylbenzene sulfonate, a safe and effective amount of ascorbic acid; and optionally a safe and effective amount of an excipient, e.g., magnesium stearate. The composition may further comprise a safe and effective amount of an antibiotic, a safe and effective amount of stearic acid, a dermatologically acceptable cream compound, a chlorine compound, and/or an abrasion material.

Abstract: Compositions and methods are disclosed for repairing damaged keratin fibers or otherwise strengthening keratin fibers, including hair of the human scalp, and particularly hair that has been damaged chemically, physically, thermally or by other means. The compositions comprise 3,3?-thiodipropionic acid (TDPA) or a derivative thereof in a cosmetically acceptable vehicle.

Abstract: The present invention relates to phytosanitary compositions with fungicidal properties that comprise one essential oil obtained from plants selected from oregano oil (Origanum vulgare) and thyme oil (Thymus vulgaris) or its active compounds carvacrol at a concentration between 0.1 and 530 ppm or thymol at a concentration between 0.31 and 530 ppm, or a combination thereof; and (2) potassium carbonate at a concentration between 3.5 and 25 mM, and an agent with known fungicidal properties for use, principally, in contact-protection against fungal infections in cultivated plants and post-harvest, and also in other antifungal applications. In said compositions, the effect of the agents that have known fungicidal properties is potentiated synergistically by the aforementioned essential oils.

Abstract: Described herein are aqueous oral care compositions comprising (a) an effective amount of a basic amino acid in free or orally acceptable salt form; and (b) a polymer system comprising (i) a cellulosic polymer, (ii) a gum polymer, and (iii) a polyacrylate polymer or co-polymer; and methods of making and using the same.

Abstract: A method and apparatus, for treating plaque and calculus in the mouth cavity—particularly on teeth—are disclosed. The apparatus—and accordingly the method—is comprised of introducing at least one first-component comprising a material with a redox potential for preventing anions precipitation; and introducing at least one second-component comprising a material with a redox potential for preventing cations precipitation.

Abstract: A dentifrice, such as toothpaste, containing chitosan or pharmaceutically acceptable acid addition salt thereof with fluoride ions, for use against erosive tooth demineralization, and kits containing chitosan or pharmaceutically acceptable acid addition salt thereof with fluoride ions, wherein one of the two active agents is comprised in a dentifrice, are described. The dentifrice in the form of toothpaste may furthermore comprise dissolved tin, in particular stannous ions. Toothpastes containing chitosan or pharmaceutically acceptable acid addition salt thereof with fluoride ions are tested in the treatment or prevention of erosive tooth demineralisation caused by citric acid.

Abstract: This invention relates to oral care compositions comprising zinc phosphate, a first source of stannous (e.g., stannous fluoride); and a second source of stannous, wherein the second source of stannous comprises stannous pyrophosphate, as well as to methods of using and of making these compositions.

Abstract: The disclosure describes methods and compositions for reducing the duration of hyperglycemia and treating diabetes and complications thereof. A human subject with hyperglycemia is administered insulin, a water-based beverage, and a sodium salt formulation sufficient to accelerate said subject's return to a non-hyperglycemic state. This process can be repeated multiple times within a given time period.

Abstract: Disclosed are anti-erosion oral care formulations and methods that provide erosion protection while maintaining adequate cleaning performance. The anti-erosion oral care formulations include a copolymer of a methylvinyl ether and a maleic anhydride and a metal compound or salt that becomes more soluble at acidic pH.

Abstract: Oral care compositions comprising a neutral amino acid and stannous ion source are provided for promoting Gum Health of a user.

Abstract: Teeth can be hardened and made more resistant to acid damage if treated with compositions that allow for the remineralization and demineralization of minerals found in teeth. Exchanging ions in hydroxyapatite for fluoride or other metal ions can result in teeth that are more resistant to chemical and physical insults.

Abstract: An oral care composition comprising zinc phosphate, stannous fluoride, an anionic polymer, and a basic amino acid, as well as methods of using the same.

Abstract: An oral care composition comprising high water oral care compositions comprising an orally acceptable carrier, zinc phosphate, a first stannous ion source (i.e., stannous fluoride), and a second stannous ion source (i.e., stannous chloride). Methods and uses for this composition are also described throughout.

Abstract: Oral care compositions and methods for whitening and preventing stains on teeth are provided. The oral care composition may include an orally acceptable vehicle, a peroxide whitening agent, and an abrasive system. The orally acceptable vehicle may include a block copolymer of ethylene oxide and propylene oxide, and the abrasive system may include at least one insoluble phosphate salt.