Dentifrices (includes Mouth Wash) Patents (Class 424/49)
  • Patent number: 11369551
    Abstract: Oral care compositions with silica particles and stannous fluoride with an improved tin compatibility are disclosed. Oral care compositions with silica particles and stannous fluoride with a low level of an additional tin compound are disclosed. Oral care compositions with substantially spherical silica particles are disclosed.
    Type: Grant
    Filed: December 3, 2019
    Date of Patent: June 28, 2022
    Assignee: The Procter & Gamble Company
    Inventors: Lawrence Edward Dolan, William Michael Glandorf, Sanjeev Midha, Eva Schneiderman, Carl E. Catrenich, Marianne Zsiska
  • Patent number: 11351097
    Abstract: This invention relates to a oral care compositions, and in particular to oral care mouthrinse compositions comprising (i) at least one source of ionic tin; and (ii) an antibacterial system comprising caprylyl glycol and 3-phenyl-1-propanol, as well as to methods of using and of making these compositions.
    Type: Grant
    Filed: December 30, 2015
    Date of Patent: June 7, 2022
    Assignee: Colgate-Palmolive Company
    Inventors: Ruth Hinrichs, Hans Stettler, Turan Matur
  • Patent number: 11351193
    Abstract: The present invention relates to compositions for mineralizing a dental surface, in particular tooth enamel. Methods of mineralizing hypomineralized lesions (including subsurface lesions) in the tooth enamel caused by dental caries, dental corrosion and fluorosis are also provided. In particular, the invention relates to a method of mineralizing a dental surface or subsurface comprising contacting the dental surface or subsurface with a compound that is capable of increasing or maintaining the pH of a solution and a mineralizing agent.
    Type: Grant
    Filed: April 20, 2020
    Date of Patent: June 7, 2022
    Assignee: THE UNIVERSITY OF MELBOURNE
    Inventor: Eric Charles Reynolds
  • Patent number: 11344058
    Abstract: An atomizing liquid gel with reversible phase transition characteristics includes: a sugar-based gelling agent, 0.1-3.0 wt %; an atomizing liquid, 97.0-99.9 wt %; a molecule of the sugar-based gelling agent is a sugar molecule introduced with an amide group and/or an aryl group, and the sugar molecule optionally further includes at least one hydrophobic structural part selected from —CxHy, —O—CxHy and and x>2 and y>2. The atomizing liquid gel has characteristics of thermal reversible phase transition and/or shear reversible phase transition, a temperature of gel-sol phase transition is 100° C.-248° C., and a critical shear stress of the gel-sol phase transition is 40-800 Pa. Under heating and/or oscillation, the atomizing liquid gel converts from the gel state to a sol state, and the atomizing agent fixed in the gel releases to form an inhalable aerosol.
    Type: Grant
    Filed: June 4, 2020
    Date of Patent: May 31, 2022
    Assignee: CHINA TOBACCO YUNNAN INDUSTRIAL CO., LTD
    Inventors: Yi Han, Wei Zhao, Xiaowei Gong, Donglai Zhu, Tinghua Li, Shoubo Li, Xia Zhang, Liu Hong, Jun Wu, Yongkuan Chen, Xi Lv, Siyao Liao
  • Patent number: 11337912
    Abstract: This application provides, among other things, novel aqueous oral care compositions useful for combining and delivering poorly compatible ingredients, for example to deliver effective levels of cationic antibacterial agents in combination with anionic polymers that protect against erosion and staining, by addition of a stabilizing amount of a polyamine, e.g., lysine, and methods for making and using the same.
    Type: Grant
    Filed: December 1, 2016
    Date of Patent: May 24, 2022
    Assignee: Colgate-Palmolive Company
    Inventors: Carl Myers, Rehana Begum-Gafur
  • Patent number: 11338021
    Abstract: The invention provides combination therapy for use in treating a bacterial biofilm in a subject comprising (a) a polypeptide having serine protease activity and (b) one or more antibiotic compounds. Also provided are compositions and methods of use of the same.
    Type: Grant
    Filed: July 22, 2016
    Date of Patent: May 24, 2022
    Assignee: ENZYMATICA AB
    Inventors: Ágústa GuÐmundsdóttir, Reynir Scheving
  • Patent number: 11340174
    Abstract: Effective monitoring of the acid/base physiology of dental plaque is considered in caries risk assessment. The invention provides a methodology for caries risk assessment and a kit of biochemical tests for acid/alkali generation in dental plaque and in saliva as a screening instrument for identifying subjects with caries. The invention provides simple chair-side tests that measure the ability of dental plaque and/or saliva to metabolize sugars concomitantly with the ability to metabolize urea and other salivary nitrogenous substrates.
    Type: Grant
    Filed: February 13, 2017
    Date of Patent: May 24, 2022
    Assignee: University of Puerto Rico
    Inventor: Evangelia Morou-Bermudez
  • Patent number: 11324677
    Abstract: Disclosed herein are oral care compositions comprising a peroxide whitening complex in an amount to provide from 3.5% to 7% of hydrogen peroxide by weight of the composition, and a block copolymer of ethylene oxide and propylene oxide in an amount of from 40% to 60% by weight of the composition. Methods of making and using the dentifrices are also provided.
    Type: Grant
    Filed: November 5, 2021
    Date of Patent: May 10, 2022
    Assignee: Colgate-Palmolive Company
    Inventors: Xiang Chen, Suman Chopra, Lin Fei
  • Patent number: 11291235
    Abstract: Provided herein is a method of reducing the off-taste of a food or beverage wherein the off-taste is selected from the group consisting of licorice, astringency, bitterness and sweet lingering comprising adding about 10 to about 40 ppm, phloretin to the food or beverage wherein the phloretin is provided in the substantial absence of a bitterness-masking aroma substance selected from the groups consisting of homoeriodictylol, homoeriodictyol sodium salt, homoeriodictylol potassium salt or mixtures thereof and wherein the phloretin does not significantly enhance the sweetness of the article or composition.
    Type: Grant
    Filed: January 19, 2017
    Date of Patent: April 5, 2022
    Assignee: Firmenich SA
    Inventors: Maxime Delattre, Jean-Luc Gelin, Long In Lou, Ronald H. Skiff
  • Patent number: 11278477
    Abstract: Described herein are oral care compositions comprising a combination of zinc oxide and zinc citrate, and methods of preparing and using the same.
    Type: Grant
    Filed: May 17, 2019
    Date of Patent: March 22, 2022
    Assignee: Colgate-Palmolive Company
    Inventors: Michael Prencipe, Yun Xu, Xiao Yi Huang, Steven Fisher, Betty Won, Lyndsay Schaeffer-Korbylo
  • Patent number: 11273122
    Abstract: The present invention relation to an oral care composition comprising a cannabinoid and at least one pharmaceutical active component is provided in which the at least one pharmaceutical active component improves oral health beyond benefits provided by the at least one cannabinoid alone. The at least one pharmaceutical active component can be Manuka honey. The oral care composition can be used in an oral care product for whitening or bleaching teeth.
    Type: Grant
    Filed: February 11, 2020
    Date of Patent: March 15, 2022
    Inventor: Therese Mainella
  • Patent number: 11260039
    Abstract: Improved methods of causing vasodilation in a human subject are disclosed. In one implementation, the human subject is administered a dose of a nitrate salt of arginine, norvaline, or ornithine, wherein the dose of the nitrate salt of the amino acid in moles of the amino acid is less than a molar amount of the amino acid needed to cause vasodilation in the human subject. In another implementation, the human subject is administered a composition comprising a dose of a nitrate salt and an amount of an amino acid, wherein the dose of the nitrate salt in the composition in moles of the nitrate salt is less than a molar amount of the nitrate salt that needs be administered alone in order to induce vasodilation in the human subject. The amino acid in the composition is selected from the group consisting of: arginine, citrulline, creatine, glutamine, leucine, norvaline, and ornithine.
    Type: Grant
    Filed: January 8, 2020
    Date of Patent: March 1, 2022
    Assignee: THERMOLIFE INTERNATIONAL, LLC
    Inventors: Alexandros Nikolaidis, Ronald Kramer
  • Patent number: 11254725
    Abstract: The present invention relates in general to therapeutic fusion proteins useful to treat lysosomal storage diseases and methods for treating such diseases. Exemplary therapeutic fusion proteins comprise a lysosomal enzyme, a lysosomal targeting moiety, e.g., an IGF-II peptide, and a spacer peptide. Also provided are compositions and methods for treating Mucopolysaccharidosis Type IIIB (Sanfilippo B Syndrome), comprising a targeted therapeutic fusion protein comprising alpha-N-acetylglucosaminidase (Naglu), a lysosomal targeting moiety, e.g., an IGF-II peptide, and a spacer peptide.
    Type: Grant
    Filed: April 8, 2019
    Date of Patent: February 22, 2022
    Assignee: BIOMARIN PHARMACEUTICAL INC.
    Inventors: Mika Aoyagi-Scharber, Teresa Margaret Christianson, Melita Dvorak-Ewell, Daniel J. Wendt, Shinong Long, Jonathan LeBowitz, Daniel Solomon Gold
  • Patent number: 11253451
    Abstract: Disclosed are oral care compositions having reduced tooth staining propensity and comprising in a pharmaceutically acceptable carrier, a cationic antimicrobial agent and an anti-stain agent comprising one or more materials from each of at least two of the following chemical groups: Group 1. anionic agents, Group 2. aldehydes, ketones, and other reactive carbonyl compounds and Group 3. nonionic ethoxylated surfactants. Examples of cationic antimicrobial agent include quaternary ammonium compounds such as cetylpyridinium chloride, cetyl pyridinium fluoride, tetradecylpyridinium chloride, N-tetradecyl-4-ethyl pyridinium chloride and domiphen bromide; chlorhexidine; and metal ion sources to supply metal ions such as stannous, zinc or copper.
    Type: Grant
    Filed: February 4, 2020
    Date of Patent: February 22, 2022
    Assignee: The Procter & Gamble Company
    Inventors: Niranjan Ramji, Douglas Craig Scott
  • Patent number: 11253468
    Abstract: An organic toothpaste is a Pickering emulsion having a particle stabilizer bound in the interface between the continuous phase and dispersed phase of the emulsion. The particle stabilizer prevents the dispersed phase from coalescing and phase separating. The emulsion may include glycerin and water to form the emulsion and particles, such as erythritol and/or rice powder as the stabilizer. An organic toothpaste may be certified USDA organic and contain no more than 5% by weight of components list of allowed substances, found in the Electronic Code of Federal Regulations, Subpart G published on May 24, 2018. An organic toothpaste may include a foaming component such as saponin, soapbark, decyl glucoside or Quillaja saponaria. In addition, an organic toothpaste may include a natural sweetener such as agave, xylitol or erythritol.
    Type: Grant
    Filed: July 12, 2021
    Date of Patent: February 22, 2022
    Assignee: Radius Corporation
    Inventor: Saskia Coleman
  • Patent number: 11253449
    Abstract: An oral care composition comprising primarily insoluble forms of zinc compounds and stannous compounds, as well as methods of using the same in the treatment or prevention of gingivitis, plaque, and dental caries.
    Type: Grant
    Filed: December 19, 2019
    Date of Patent: February 22, 2022
    Assignee: Colgate-Palmolive Company
    Inventors: Iraklis Pappas, Zhichao Hu, Donghui Wu
  • Patent number: 11253444
    Abstract: The present invention relates to an oral care composition for use in the treatment or prevention of erosive tooth demineralization, plaque, and caries. This oral care composition includes zinc lactate dihydrate, a stannous ion source, at least one phosphate salt, and a buffer system.
    Type: Grant
    Filed: June 24, 2016
    Date of Patent: February 22, 2022
    Assignee: Colgate-Palmolive Company
    Inventors: Nihal Dogu, Kavita Vemishetti
  • Patent number: 11246854
    Abstract: Described are methods of treating or preventing a virus in a subject comprising administering ozonides to the subject.
    Type: Grant
    Filed: May 15, 2018
    Date of Patent: February 15, 2022
    Assignees: THE JOHNS HOPKINS UNIVERSITY, UNIVERSITY OF NEBRASKA MEDICAL CENTER
    Inventors: Ravit Boger, Jonathan Vennerstrom
  • Patent number: 11241474
    Abstract: The present invention provides an oral care composition comprising: (a) a dipeptide of the formula Xaa1-Xaa2 or Xaa2-Xaa1; wherein Xaa1 is an amino acid with a polar uncharged side chain; and Xaa2 is selected from an amino acid with a hydrophobic side chain, an amino acid with a polar uncharged side chain, and proline; or (b) a dipeptide of the formula Xaa3-Xaa4 or Xaa4-Xaa3; wherein Xaa3 is an amino acid with a hydrophobic side chain; and Xaa4 is selected from an amino acid with a hydrophobic side chain and an amino acid with a charged side chain.
    Type: Grant
    Filed: November 9, 2018
    Date of Patent: February 8, 2022
    Assignees: Colgate-Palmolive Company, Katholieke Universiteit Leuven, Universiteit Gent
    Inventors: Hansruedi Stettler, Wim Teughels, Marc Quirynen, Nico Boon
  • Patent number: 11241452
    Abstract: The present invention describes a mucoadhesive composition comprising chondroitin sulfate, xyloglucan and glycerol for use in the treatment and prevention of gastroesophageal reflux. It is also described a process for preparing such composition, a dosage form for its administration and a kit comprising the same.
    Type: Grant
    Filed: September 18, 2018
    Date of Patent: February 8, 2022
    Assignee: ALFASIGMA S.P.A.
    Inventors: Paola Maffei, Marco Mascagni, Giuseppe Claudio Viscomi
  • Patent number: 11234450
    Abstract: Proposed are preparations, comprising special amides and menthol or menthol compounds or aromatic substances, characterized in that they have improved flavor and scent properties, and also that they allow the production of preparations, particularly emulsions with improved shelf life.
    Type: Grant
    Filed: November 6, 2017
    Date of Patent: February 1, 2022
    Assignee: Symrise AG
    Inventors: Torsten Kulke, Sven Siegel, Michael Backes, Benoit Join, Hubert Loges, Günter Kindel
  • Patent number: 11229588
    Abstract: A storage-stable solid composition comprising a tooth whitening effective amount of a particulated inorganic salt of peroxymonosulfate, and a particulated drying agent.
    Type: Grant
    Filed: June 10, 2020
    Date of Patent: January 25, 2022
    Assignee: Colgate-Palmolive Company
    Inventors: Rolando B. Plata, Devendra Chavan, Shashank Vishwanath Potnis, Manisha Jha
  • Patent number: 11229582
    Abstract: The present invention provides a patch for attaching to teeth or a surrounding part of teeth, and the patch can be easily removed by tooth brushing alone.
    Type: Grant
    Filed: August 30, 2016
    Date of Patent: January 25, 2022
    Inventors: Jong-Hoon Kim, Jae-Hyun Ahn, Kwang-Ho Oh, In-Ho Lee, Woo-Sun Shim
  • Patent number: 11219580
    Abstract: The present invention provides a mouthwash composition comprising a heterogeneous gel, wherein said heterogeneous gel comprises at least two gelling agents and two or more active ingredients, and wherein the composition provides the differential release of the active ingredients over a period of time.
    Type: Grant
    Filed: April 28, 2017
    Date of Patent: January 11, 2022
    Assignee: ANDALAY TECHNOLOGIES LIMITED
    Inventors: Andrew Mark Shaw, Tim Holdway, Alasdair Dow
  • Patent number: 11208560
    Abstract: The present invention relates to spherical, dense micrometre-sized particles comprising colourants. The invention also relates to a material comprising these particles intended for use in papermaking, paint, agri-food, cosmetics or pharmaceuticals. It also relates to the process for preparing these particles and their incorporation in a matrix.
    Type: Grant
    Filed: November 10, 2016
    Date of Patent: December 28, 2021
    Assignee: PYLOTE
    Inventors: Loïc Marchin, Marie-Laure Desse
  • Patent number: 11211249
    Abstract: The invention provides a method for preparing an herbal extract and a flavor system comprising an herbal extract produced by the process. The invention also provides a flavor system comprising an herbal extract comprising thymol, eugenol, carvacrol and eucalyptol. The invention further provides a flavor system comprising a thyme extract having a minimum inhibitory concentration of less than about 3%. Additionally, the invention provides an oral product comprising a flavor system.
    Type: Grant
    Filed: June 6, 2012
    Date of Patent: December 28, 2021
    Assignee: Sensient Flavors LLC
    Inventors: Kenneth John Hughes, Sylvia Gaysinsky, Roger Michael Browning
  • Patent number: 11191981
    Abstract: Non-aqueous dentifrice compositions comprising an alkaline earth metal acetate salt such as strontium acetate and/or an alkaline earth metal nitrate salt such as strontium nitrate; a carboxyvinyl polymer and a humectant.
    Type: Grant
    Filed: December 18, 2017
    Date of Patent: December 7, 2021
    Assignee: GlaxoSmithKline Consumer Healthcare (UK) IP Limited
    Inventor: Shazada Yassar Khan
  • Patent number: 11185489
    Abstract: Disclosed is a system and method for the delivery, into interdental spaces, of oral care active agents contained in particles. The particles are made of one or more superabsorbent polymers (SAP), and are of size generally small enough to be easily applied into an interdental space. To this end, the particles typically have a length of below 1.5 mm. By virtue of the SAP's ability of absorbing several times its own weight in water, the particles will swell once in contact with saliva. As a result, the volume of the particles as applied in between teeth increases by at least eight times, thereby effectively making the particles larger than the average interdental gap size. The particles, once swollen, are thus held more firmly between the walls of the interdental space, thus preventing them from being easily washed away.
    Type: Grant
    Filed: March 23, 2018
    Date of Patent: November 30, 2021
    Assignee: KONINKLIJKE PHILIPS N.V.
    Inventors: Maaike Cornelia Johanna Wilhelmina Van Hulten, Bart Gottenbos, Carl Glasse
  • Patent number: 11160753
    Abstract: Provided herein are transmucosal and transdermal delivery systems comprising: at least one non-ionic surfactant; at least one polyol; and at least one active agent; and optionally further comprising at least one oil. In particular embodiments, the delivery system has an average particle size of from about 5 nm to about 200 nm.
    Type: Grant
    Filed: March 2, 2016
    Date of Patent: November 2, 2021
    Assignee: Medlab Clinical U.S., Inc.
    Inventors: David A. Rutolo, Jr., Sean Michael Hall, Luis Vitetta, Yusi Zhou, Samantha Maree Coulson
  • Patent number: 11154468
    Abstract: This invention relates to oral care compositions comprising a zinc source comprising zinc oxide and zinc citrate; a stannous source comprising stannous pyrophosphate; a fluoride ion source comprising sodium fluoride; and an organic buffer, as well as to methods of using and of making these compositions.
    Type: Grant
    Filed: September 19, 2017
    Date of Patent: October 26, 2021
    Assignee: Colgate-Palmolive Company
    Inventors: Aarti Rege, Michael Prencipe, Paul Thomson
  • Patent number: 11147746
    Abstract: An example article may include a dental surface, a hydrophobic coating on the dental surface, and a restorative layer on the hydrophobic coating. An example technique may include applying, on a dental surface, a hydrophobic coating comprising an amphiphilic agent. The hydrophobic coating may provide a water contact angle of greater than or equal to about 50° on the dental surface. The example technique may include applying a restorative layer to the hydrophobic coating. An example kit may include a dental restorative composition and a hydrophobic coating composition. The hydrophobic coating composition may include an amphiphilic agent. The hydrophobic coating composition may be configured to provide a water contact angle of greater than or equal to about 50° on a dental surface.
    Type: Grant
    Filed: June 21, 2017
    Date of Patent: October 19, 2021
    Assignee: Regents of the University of Minnesota
    Inventors: Conrado Aparicio, Alex Fok, Dina G. Moussa, Brian Holmes, William H. Douglas
  • Patent number: 11134676
    Abstract: This invention relates to anti-microbial active particles, compositions and uses thereof for inhibiting bacterial growth on surfaces or devices. This invention further discloses methods of making such anti-microbial active particles.
    Type: Grant
    Filed: August 30, 2018
    Date of Patent: October 5, 2021
    Assignee: NOBIO LTD.
    Inventors: Nathan Zaltsman, Ervin I. Weiss
  • Patent number: 11135144
    Abstract: The present disclosure provides low water dentifrice compositions comprising an effective amount of a zinc ion source, a tin ion source, a polyphosphate and an acid. The acid lowers the pH of the composition to enable stabilization of the metal ions and extend shelf-life of the composition.
    Type: Grant
    Filed: December 26, 2014
    Date of Patent: October 5, 2021
    Assignee: Colgate-Palmolive Company
    Inventors: Kavita Vemishetti, Linh Fruge, Michael Prencipe
  • Patent number: 11123170
    Abstract: Methods produce a three-dimensional dental block of material from a dental, polymerizable material. The methods include at least: transferring the polymerizable dental material into a radiolucent three-dimensional casting or press mold; irradiating the polymerizable dental material substantially from all sides with light in the UV/Vis spectral region forming polymerized outer surfaces of the dental material in the form of a solid outer shell of the dental material, wherein the shell is present in the defined three-dimensional geometry of the material whilst the inner region of the material is not polymerized or partially polymerized; heating the material with solid shell being present in defined three-dimensional geometry, to 60° C. to 150° C. for at least 90 minutes; and obtaining a dental, polymerized block of material having defined three-dimensional geometry.
    Type: Grant
    Filed: December 14, 2016
    Date of Patent: September 21, 2021
    Assignee: KULZER GMBH
    Inventors: Klaus Ruppert, Alfred Hohmann
  • Patent number: 11116841
    Abstract: The present disclosure provides biophotonic topical compositions, kits and their uses. In particular, the biophotonic compositions of the present disclosure are substantially resistant to leaching such that very low amounts of chromophore(s) present in the biophotonic composition leach out of the composition. The biophotonic compositions and their uses are useful for promoting wound healing and skin rejuvenation, as well as treating acne and various skin disorders.
    Type: Grant
    Filed: April 19, 2013
    Date of Patent: September 14, 2021
    Assignee: KLOX TECHNOLOGIES INC.
    Inventors: Nikolaos Loupis, Remigio Piergallini, Shipra Rastogi
  • Patent number: 11103447
    Abstract: Provided herein is a storage stable non-fluoride toothpaste composition enriched with a dietary supplement containing both oil soluble and water soluble vitamins. The dietary supplement is incorporated into the toothpaste, the dietary supplement containing a water soluble vitamin portion including at least one water soluble vitamin and an oil soluble vitamin portion. The oil soluble vitamin portion includes at least one oil soluble vitamin, a carrier oil and an emulsifier. The toothpaste is thereby formulated in a manner such that oral application will result in systemic delivery of at least a portion of the dietary supplement to meet a 2% RDI threshold even when 3 or less serving sizes are orally applied.
    Type: Grant
    Filed: September 27, 2019
    Date of Patent: August 31, 2021
    Assignee: Golden Products LLC
    Inventor: Bruce Alan Golden
  • Patent number: 11077051
    Abstract: A shear-thinning therapeutic composition is provided along with methods of making and using the therapeutic composition.
    Type: Grant
    Filed: September 15, 2017
    Date of Patent: August 3, 2021
    Assignee: University of Pittsburgh—Of the Commonwealth System of Higher Education
    Inventors: Xiaochu Ding, Jin Gao, Yadong Wang
  • Patent number: 11073470
    Abstract: Provided herein is a biosensor for conformation and secondary structure analysis, notably for the direct non-invasive qualitative secondary structure analysis of a single selected protein within a complex mixture, as e.g. a body fluid, by vibrational spectroscopic methods. For the analysis it is not required that the selected substance be isolated, concentrated, or pretreated by a special preparative procedure.
    Type: Grant
    Filed: February 12, 2015
    Date of Patent: July 27, 2021
    Assignee: Betasense GMBH
    Inventors: Klaus Gerwert, Jens Wiltfang, Julian Ollesch, Andreas Nabers, Jonas Schartner, Carsten Kötting
  • Patent number: 11071697
    Abstract: The present invention relates to an antibacterial composition which, when applied to the surface of a tooth, allows remineralisation of the enamel to occur, said composition having very low toxicity for human use. When applied, the composition leaves no stains and does not alter the visible colour characteristics of the teeth to which it has been applied.
    Type: Grant
    Filed: November 15, 2017
    Date of Patent: July 27, 2021
    Assignee: UNIVERSIDAD DE CHILE
    Inventors: Humberto Cristian Palza Cordero, Mario Rodrigo Diaz Dosque, Rodrigo Antonio Cabello Ibacache
  • Patent number: 11058628
    Abstract: An organic toothpaste is a Pickering emulsion having a particle stabilizer bound in the interface between the continuous phase and dispersed phase of the emulsion. The particle stabilizer prevents the dispersed phase from coalescing and phase separating. The emulsion may include glycerin and water to form the emulsion and particles, such as erythritol and/or rice powder as the stabilizer. An organic toothpaste may be certified USDA organic and contain no more than 5% by weight of components list of allowed substances, found in the Electronic Code of Federal Regulations, Subpart G published on May 24, 2018. An organic toothpaste may include a foaming component such as saponin, soapbark, decyl glucoside or Quillaja saponaria. In addition, an organic toothpaste may include a natural sweetener such as agave, xylitol or erythritol.
    Type: Grant
    Filed: August 28, 2020
    Date of Patent: July 13, 2021
    Assignee: RADIUS Corporation
    Inventor: Saskia Coleman
  • Patent number: 11058714
    Abstract: A method of inhibiting or reducing inflammation in a mammal comprises administering MCP or similar Gal-3 binding moiety with honokiol in a range of about 8-10:1, by weight, MCP to honokiol. By pursuing complimentary pathways, a synergistic combination is achieved, where the reduction or degree of inflammation inhibition is greater than would be expected by the added administration of these two agents. The inflammation may be manifested as gingivitis, which may be addressed by a preparation comprising honokiol and MCP, or an MCP equivalent, in the indicated range by weight, where they are in the form of an oral rinse, lozenge, sucking candy, toothpaste or tablet.
    Type: Grant
    Filed: June 12, 2019
    Date of Patent: July 13, 2021
    Assignee: ECONUGENICS, INC.
    Inventor: Isaac Eliaz
  • Patent number: 11033485
    Abstract: A dental care system having from about 30 to 99 wt. % humectant; from about 1 to 50 wt. % water; from about 0.001 to 5.00 wt. % antiplaque and anti-tartar actives; from about 0 to 25 wt. % oil; from about 25 to 1 wt. % surfactant; and wherein the dental care system is hydrophobic and adheres to wet gums.
    Type: Grant
    Filed: May 13, 2020
    Date of Patent: June 15, 2021
    Inventors: Alvin Kershman, Jeff L Shear
  • Patent number: 11026917
    Abstract: Antioxidative stress compositions, methods of using antioxidative stress composition and methods of preparing antioxidative stress composition compositions are described. The antioxidative stress compositions may be chemopreventive and/or immunomodulatory. Resveratrol, genistein, ellagic acid, curcumin and quercetin may be included in the antioxidative stress composition compositions individually or in any combination.
    Type: Grant
    Filed: August 5, 2019
    Date of Patent: June 8, 2021
    Inventor: John Michael Pezzuto
  • Patent number: 11021600
    Abstract: Modelling material which contains (a) at least one radically polymerizable monomer, (b) at least one initiator for the radical polymerization and (c) at least one inert component. The inert component (c) is selected from phthalates, polyethylene glycols (PEG), polypropylene glycols (PPG), PEG-PPG copolymers, glycerol derivatives, ethoxylated or propoxylated glycerol, ethylenediamine tetrakispropoxylates and ethylenediamine tetrakisethoxylates. The material is suitable in particular for the production of models of dental restorations for investment casting processes.
    Type: Grant
    Filed: December 7, 2017
    Date of Patent: June 1, 2021
    Assignee: Ivoclar Vivadent AG
    Inventor: Lorenz Josef Bonderer
  • Patent number: 11013672
    Abstract: Oral care compositions containing a stannous salt and sodium tripolyphosphate are provided where stannous tripolyphosphate ionic intermediates comprise less than about 1% of the compositions. Tetrasodium pyrophosphate, a methylvinyl ether-maleic anhydride copolymer and/or a silica oral polishing agent may be added for further efficacy. In a single phase blend, the oral care composition may be effectively limited to comprise less than about 10% water. In a dual-phase blend, a mixture having the stannous salt in a first phase and the sodium tripolyphosphate in a second phase may be generated from a dual chamber storage tube (with each phase provided from a separate chamber) immediately prior to dental care usage.
    Type: Grant
    Filed: April 25, 2018
    Date of Patent: May 25, 2021
    Assignee: Colgate-Palmolive Company
    Inventors: James R. Brown, Linh Fruge, Tao Xu, Michael Prencipe
  • Patent number: 11008345
    Abstract: This invention relates to, among other items, benzoxaborole compounds and their use for treating bacterial infections.
    Type: Grant
    Filed: July 30, 2019
    Date of Patent: May 18, 2021
    Assignee: Anacor Pharmaceuticals, Inc.
    Inventors: Vincent S. Hernandez, Charles Ding, Jacob J. Plattner, Michael Richard Kevin Alley, Fernando Rock, Suoming Zhang, Eric Easom, Xianfeng Li, Ding Zhou
  • Patent number: 11007143
    Abstract: Copper ion treatments and methods of treatment are provided to treat various body conditions affecting the oral, respiratory and/or otic areas of the body. The copper ion treatments contain copper ions which bring about local and systemic therapeutic effects as a result of contacting anatomical tissue of the oral cavity, the nasal passages or ear canal. The copper ion treatments and methods involve copper ion-containing solutions, copper ion toothpaste and copper ion mouthwash. The copper ion-containing solutions can be delivered to the oral cavity by spraying or swabbing, can be delivered to the nostrils as spray, drops, or by swabbing, and can be delivered to the ear canal as spray, drops, or by swabbing. The copper ion toothpaste is used for brushing the teeth, and the copper ion mouthwash is used for rinsing the mouth.
    Type: Grant
    Filed: March 15, 2013
    Date of Patent: May 18, 2021
    Assignee: CDA RESEARCH GROUP, INC.
    Inventors: ChunLim Abbott, Dominic C. Abbott
  • Patent number: 11000710
    Abstract: The composition and method for the use of stabilized chlorine dioxide as an antimicrobial agent against oral microorganisms for the treatment and prevention of halitosis and prevention of oral diseases, wherein the activation and release of chlorine dioxide from the composition a) occurs rapidly and without a period of induction, b) results from the oxidative reduction and consumption of amino acids and volatile sulfur compound precursors, and c) generates twice the available chlorine dioxide gas as that generated from simply lowering the pH of the composition. The preferred concentrations of stabilized chlorine dioxide in this invention are in the range of 0.005% to 2.0% (w/v) wherein the pH of the composition is initially lowered by a citrate and then stabilized by a peroxy compound.
    Type: Grant
    Filed: May 25, 2017
    Date of Patent: May 11, 2021
    Assignee: Micropure, Inc.
    Inventors: Martin C. Grootveld, Christopher J. L. Silwood, James L. Ratcliff
  • Patent number: 10993888
    Abstract: Fluorescent nanoparticle compositions and methods of used for dental bonded restorations are provided herein.
    Type: Grant
    Filed: December 20, 2018
    Date of Patent: May 4, 2021
    Assignee: AUGUSTA UNIVERSITY RESEARCH INSTITUTE, INC.
    Inventors: Marcelo Giannini, Rafael Rocha Pacheco, Frederick Allen Rueggeberg, Jorge Rodrigo Soto Montero, Eduardo David Martinez, Ali Francisco Garcia Flores, Ailla Carla Rocha Acosta Lancellotti, Guilherme Gorgen Lesseux, Carlos Rettori, Ricardo Rodrigues Urbano
  • Patent number: 10988579
    Abstract: The present invention relates to a organopolysiloxane graft polymer including an organopolysiloxane segment as a main chain thereof and an unsaturated monomer-derived polymer segment as a side chain thereof, in which the unsaturated monomer-derived polymer segment contains a repeating unit derived from N,N-dimethyl acrylamide in an amount of not less than 50% by mass and not more than 100% by mass, and a content of the organopolysiloxane segment in the organopolysiloxane graft polymer is not less than 10% by mass and not more than 70% by mass.
    Type: Grant
    Filed: February 13, 2018
    Date of Patent: April 27, 2021
    Assignee: KAO CORPORATION
    Inventors: Tomoka Maekawa, Shuichiro Kobaru, Chihiro Miyazaki