Abstract: Silica particles having a BET surface area from 0.1 to 7 m2/g, a pack density from 35 to 55 lb/ft3, an Einlehner abrasion value from 8 to 25 mg lost/100,000 revolutions, a total mercury intrusion pore volume from 0.7 to 1.2 cc/g, and a stannous compatibility from 70 to 99%, are disclosed, as well as methods for making these silica particles.

Abstract: Novel tris-substituted biguanide compounds are made by reaction of sodium dicyanamide with a trifunctional primary amine followed by reaction with anilines. The tris-substituted biguanide compounds are potent biocide and useful as a disinfectant. The novel compounds have biocidal activity comparable to those of widely used chlorhexidine with respect to width of antibacterial spectrum and in immediate effectiveness. The novel tris-substituted biguanide compounds can also be used for cleaning wounds, preventing dental plaque, treating yeast infections of the mouth, and to keep urinary catheters from blocking, These novel compounds have superior aqueous solubility and bioavailability and have potent antibacterial activity especially against A. baumanni and K. pneumonia.

Abstract: Disclosed is a copolymer that includes a repeat unit containing a flavorant-containing pendant and a salt-containing repeating unit. In addition, a comestible, a smoking composition, a smoking article, a smokeless tobacco composition and a heatable or combustible product are provided which incorporate one or more of the flavorant-containing copolymer.

Abstract: Disclosed herein are oral care compositions comprising hemp seed oil and caprylyl glycol. In certain embodiments, the oral care composition optionally further comprises one or more ingredients selected from hyaluronic acid and aloe vera. Methods of making and using the compositions are also provided.

Abstract: A water-soluble composition for bacteriostasis or for absorption through mucosal tissue which improves a cellular environment and a production method thereof are provided. The water-soluble composition contains magnesium, sodium, and protein. A content ratio between the magnesium and the sodium is magnesium:sodium=16:1 to 73:1. The protein is lactoferrin. A percentage content of the magnesium is 8.0 w/v % to 12.0 w/v %. A percentage content of the lactoferrin is 3.0 w/v % to 10.0 w/v %.

Abstract: Oral care compositions and/or unit-dose oral care compositions comprising a high level of surfactant. Oral care compositions and/or unit-dose oral care compositions with a high foaming efficiency. Oral care compositions and/or unit-dose oral care compositions with one or more web forming materials, one or more surfactants, and a sugar alcohol.

Abstract: Oral care compositions with an anticaries or anticavity effect. Oral care compositions that have one or more hops beta acids, such as from an extract from a species in the Humulus family, and one or more amino acids. Oral care compositions having one or more amino acids and an extract from Humulus lupulus. Methods of us of the disclosed compositions to disrupt biofilm in the oral cavity of a patient in need of treatment.

Abstract: A composition for improved oral care includes fibrillated material and friction elements for removal of plaque biofilm, and additional ingredients useful in oral care compositions. The composition also may include particulate SuperAbsorbent Polymer, which may be surface cross-linked. Certain ingredients may be minimized or avoided to reduce the lubricity of the composition. The composition may be a viscoelastic fluid having a desired viscosity, yield stress and elastic modulus. The efficacy can be characterized by its removal of biofilm due to flow inside tubes. Also useful are standard rheological and tribological measurements. Also disclosed are apparatus for administering the composition, and methods.

Abstract: A unit-dose dentifrice composition includes a soluble fibrous composition and a nonfibrous composition. The soluble fibrous composition includes web forming material and tin ion source. The nonfibrous composition includes abrasive. The abrasive and the tin ion source are in separate locations within the unit-dose dentifrice composition.

Abstract: A substantially anhydrous thickener system in the form of a gel for use in oral care compositions comprising: carboxymethyl cellulose or its salts thereof, a chelating agent, and hydroxyethyl cellulose, in a solvent system, wherein the thickener system is heated to a temperature ranging from about 70° C. to about 120° C. to form the gel. A method of preparing the thickener system for use in oral care compositions comprises the steps of: a) charging a mixture of hydroxyethyl cellulose and carboxymethyl cellulose into a reaction container, b) dissolving the mixture of a) in a solvent system, c) charging a chelating agent into b), and d) heating the resultant of c) to a temperature of 70°-120° C. for at least about 10 minutes.

Abstract: A plant-based composition containing an alcohol extract of Tecoma species (e.g. Tecoma stans) and an exogenous carrier and/or excipient. Also provided is a composition including a mixture of three acids, namely corosolic acid, oleanolic acid, and ursolic acid, which can be found in the Tecoma species. Methods of treating skin lesions (e.g. warts, corns, calluses, and umbilical granulomas) and reducing symptoms associated with the skin lesions using such compositions are specified.

Abstract: An oral care article in form of a strip for use in the oral cavity. The oral care article comprises a solid hydrophobic delivery carrier comprising solid hydrophilic particles comprising a bleaching agent, wherein the solid hydrophilic particles are embedded in the carrier. The concentration of the bleaching agent at a first surface of the solid delivery carrier is greater than the concentration of the bleaching agent at a second surface of the solid delivery carrier and the overall concentration of the bleaching agent is from about 0.1% to about 15% by weight of the article.

Abstract: This application discloses oral care compositions comprising cannabinoids, preferably cannabidiol and/or cannabigerol. The oral care composition disclosed in this application may be a tooth paste, a tooth powder, or a mouthwash solution. The oral care composition may be used to treat oral infectious disease, including periimplantitis, periodontitis, oral mucositis, and dental pain.

Abstract: The invention relates to a method for the detection of tooth demineralisation. More specifically, the method concerns exposing a tooth to a pharmaceutical composition comprising a complex capable of producing an optical signal characteristic of the presence of free ions and detecting the resulting optical signal, and a kit for the detection of active demineralisation at tooth surfaces using such method.

Abstract: The purpose of the present invention is to provide an ointment preparation in which both separation over time and discoloration over time are suppressed. Both separation over time and discoloration over time are suppressed in: a topical composition containing (A) 30-60 weight % of zinc chloride, a specific (B) inorganic powder and a specific (C) additive, and (D) a solvent; and a topical composition containing (A) 30-60 weight % of zinc chloride, a specific (B) inorganic powder, and (D) a solvent.

Abstract: Embodiments relate to a composition comprising nanohydroxyapatite (NHAP) in an amount about 0.5 wt. % to about 50 wt. % of the composition having a particle size in a range of about 20-100 nm, an abrasive, a sweetener, and a natural oil, wherein the composition does not contain glycerin and fluoride, wherein the composition is alkaline and a dental product, and wherein the natural oil is a plant product.

Abstract: A solid free-flowing particulate laundry detergent composition can include a particle, wherein the particle includes a continuous phase and a discontinuous phase, wherein the continuous phase includes fatty material selected from: fatty acid and/or salts thereof; fatty alcohol; and any combination thereof, wherein the discontinuous phase includes: non-ionic and/or anionic emulsifier surfactant; hydrophobized polyethylene glycol polymer; silicone and/or petrolatum; and perfume.

Abstract: A dentifrice composition and a method of making thereof are provided. The dentifrice composition includes an alginate, where the alginate is present in an amount from about 0.01 wt % to about 2 wt %, based on the total weight of the dentifrice composition; zinc compounds, wherein the zinc compounds include zinc oxide and zinc citrate trihydrate, wherein the zinc compounds are present in an amount from about 0.1 wt % to about 2 wt %, based on the total weight of the dentifrice composition; and an abrasive, wherein the abrasive includes calcium carbonate, wherein the abrasive is present in an amount from about 38 wt % to about 50 wt %, based on the total weight of the dentifrice composition.

Abstract: This application provides, among other things, novel aqueous oral care compositions useful for combining and delivering poorly compatible ingredients, in particular, chlorhexidine and polyphosphate salts, by formulating the composition with a surfactant.

Abstract: Dentifrice compositions comprising zinc ion, glycine and fluoride ion source, especially in the absence of stannous ion source, are provided for treating dental plaque biofilm.

Abstract: Compositions that include from 0.1 wt-% to 8 wt-% of one or more compounds of formula (I) based on the total weight of the composition HOCH2—(CHOH)n—CH2NR1R2??(I) wherein R1 and R2 are independently selected from the group consisting of a hydrogen atom, an alkyl group, C(O)R3, and SO2R4; with R3 and R4 being independently selected from the group consisting of an alkyl group, an aryl group, and an aralkyl group; wherein n is an integer from about 2 to about 5; from 5 wt-% to 95 wt-% of one or more plant based oils based on the total weight of the composition; from 5 wt-% to 80 wt-% water based on the total weight of the composition and from 0.01 wt-% to 1 wt-% of one or more nonionic aromatic phenolic preservatives based on the total weight of the composition wherein the composition has a pH from 4.5 to 9.5, the composition is an emulsion, and the composition is edible.

Abstract: A method for performing cold atmospheric plasma treatment of respiratory infections or lung cancer having a source of a carrier gas, a cold atmospheric plasma generator connected to the source of carrier gas, a source of compressed air, a humidifier connected to the source of compressed air, a source of oxygen, a ventilator having inputs connected to an output of the humidifier and the source of oxygen, a mixer having an interior chamber formed from a dielectric, an active electrode inside the interior chamber, and an outer electrode connected to ground, wherein the mixer has a fluid input port connected to a gas output of the cold atmospheric plasma generator and an output of the ventilator, and a delivery member connected to an output of the mixer for delivering combined humidified air and cold atmospheric plasma to a respiratory system of a patient.

Abstract: Disclosed herein are oral care compositions comprising: an orally acceptable vehicle comprising greater than about 50 wt. % water; and a preservative system comprising: benzyl alcohol, benzoic acid or a salt of benzoic acid; and an alkylene glycol. Methods of making and using these compositions are also described herein.

Abstract: An oral care composition comprising zinc phosphate, stannous fluoride and an organic acid buffer system, as well as methods of using the same.

Abstract: The present disclosure relates to a pumping type toothpaste composition capable of being provided as contained in a pumping type container, and relates to a pumping type transparent toothpaste composition comprising or not comprising an abrasive. The pumping type toothpaste composition of the present disclosure has excellent commercial value due to its transparent formulation.

Abstract: The invention relates to a medical composition comprising guanidinyl-containing polymer(s) and polyanionic polymer(s). The medical composition is useful for absorbing water-containing fluids and can be used as dental retraction composition or as part of a medical treatment device.

Abstract: A beverage can include D ethyl 3-hydroxybutyrate, D 1,3-butanediol, D Beta hydroxybutyrate salts, D Beta hydroxybutyrate/D 1,3-butanediol monoester, D ethyl hydroxybutyrate, hydroxybutyrate, and/or D hydroxybutyric acid of at least 0.5 percent by volume. The percentage of D ethyl 3-hydroxybutyrate, D 1,3-butanediol, D Beta hydroxybutyrate salts, D Beta hydroxybutyrate/D 1,3-butanediol monoester, D ethyl hydroxybutyrate, hydroxybutyrate, and D hydroxybutyric acid can be between 5 and 19 percent, or can be higher than 19 percent. The beverage can be improved by the incorporation of flavor from hops and/or from other ingredients.

Abstract: Compositions and methods for treating, reducing, or preventing a disease or symptom such as gingivitis, periodontitis, gastritis, colitis, ileitis, Crohn's disease, chronic inflammatory intestinal disease, inflammatory bowel syndrome, chronic inflammatory bowel disease, celiac disease, ulcerative colitis, a gastric ulcer, a peptic ulcer, a buccal ulcer, a nasopharyngeal ulcer, an esophageal ulcer, a duodenal ulcer, a gastrointestinal ulcer, an autoimmune disorder, or pain. The method includes identifying a patient in need of treatment and administering a therapeutically effective amount of at least one cationic steroid antimicrobial (CSA), or a pharmaceutically acceptable salt thereof. Kits comprising such compositions and instructions on such methods are also contemplated herein.

Abstract: The present invention relates to compositions for mineralizing a dental surface, in particular tooth enamel. Methods of mineralizing hypomineralized lesions (including subsurface lesions) in the tooth enamel caused by dental caries, dental corrosion and fluorosis are also provided. In particular, the invention relates to a method of mineralizing a dental surface or subsurface comprising contacting the dental surface or subsurface with a compound that is capable of increasing or maintaining the pH of a solution and a mineralizing agent.

Abstract: The semisolid oral dispersions include hydrophilic active agent particles in hydrophobic phase. The hydrophilic active agent particles can include bleaching agents, antimicrobial agents, anticalculus agents, and/or combinations thereof. The hydrophilic active agent particle can have a solubility in water of at least about 20 parts, by weight of the particles, in about 100 parts, by weight, of water.

Abstract: A toothpaste composition includes a structurant and a thickener, wherein the toothpaste composition has a predetermined viscosity and phase angle by using the structurant instead of reducing the content of a thickener, and thereby has an improved release property during use while maintaining a shape retention property of the toothpaste, and has an improved feeling of refreshment, flavor releasing power, cleaning power, and stain removal power. Further, provided is a toothpaste composition including a chelating agent containing phosphate and silica, wherein the chelating agent is supersaturated to precipitate phosphate to provide strong cleaning power, a whitening effect, a stain removal effect, and a crunchy sensation. Further, provided is a toothpaste composition including a peroxide, a thickener, and a spreading agent, wherein the peroxide and the thickener are separated from each other, providing excellent sense of use, stability, and a whitening effect in an anhydrous state.

Abstract: Disclosed are compositions that include a combination of natural tooth powder ingredients pressed into tablet form, and methods of making the composition, and to methods of enhancing dental hygiene that includes administration of the composition. The compositions include natural ingredients such as xylitol and at least one tooth cleaning agent, and can be formed into a tablet suitable for cleaning the teeth without the use of a toothbrush or water.

Abstract: An antiseptic composition comprising a multivalent cationic antiseptic present in an amount of 0.05 to 0.5 percent based upon the ready to use composition; an anionic compound which is water soluble in an amount of at least 0.1 grams in 100 grams water at 23 deg C., wherein the anionic compound is present at a concentration which would result in precipitation of the multivalent cationic antiseptic in the composition without a solubilizing surfactant present; wherein the composition, with the antiseptic, surfactant and anionic compound combined with each other, is free of precipitate.

Abstract: The present invention relates to compositions and methods for the treatment of the Charcot-Marie-Tooth disease and related disorders.

Abstract: The invention relates to a novel composition and method of manufacturing personal lubricant, commonly known as lube, to combine the most desirable features of disparate existing lube compositions to create a long lasting, oil-based, water soluble, non-toxic, anti-microbial, anti-yeast, non-staining, personal lubricant that can be organically sourced and will not damage commonly used prophylactics.

Abstract: An aqueous oral care one-part composition (e.g., solution), a kit that includes such composition (e.g., solution), and methods (e.g., a method of providing fluoride to a patients tooth surface), wherein the oral care composition (e.g., solution) includes: silver cations; thiocyanate anions; fluoride anions; and water.

Abstract: The present invention provides calcium carbonate-based oral care compositions, in particular toothpastes comprising a thickening system comprising 0.2-0.5 wt. % xanthan gum and 0.2-0.5 wt. % synthetic polyacrylic acid polymer, as well as methods of using these compositions.

Abstract: Modelling material which contains (a) at least one radically polymerizable monomer, (b) at least one initiator for the radical polymerization and (c) at least one inert component. The inert component (c) is selected from phthalates, polyethylene glycols (PEG), polypropylene glycols (PPG), PEG-PPG copolymers, glycerol derivatives, ethoxylated or propoxylated glycerol, ethylenediamine tetrakispropoxylates and ethylenediamine tetrakisethoxylates. The material is suitable in particular for the production of models of dental restorations for investment casting processes.

Abstract: A system includes a dental appliance having a polymeric shell with a plurality of cavities for receiving one or more teeth; and a biocompatible cosmetic aqueous liquid in the cavities of the polymeric shell of the dental appliance. The aqueous liquid includes a viscosity modifier chosen from a water compatible polymer, a polysaccharide, a silica compound, and mixtures and combinations thereof, a tooth re-mineralizing agent, and water. The aqueous liquid is substantially free of tooth whitening agents and fluoride, and has a refractive index of greater than 1.3 at room temperature.

Abstract: In various embodiments a dental varnish system having improved peptide release and fluoride release properties is provided. In various embodiments a dental varnish system that provides release of an antimicrobial peptide, or specifically targeted antimicrobial peptide (STAMP), e.g., the peptide C16G2, is provided, with or without a fluoride. In various embodiments, a dental varnish system that provides release of a fluoride, with or without an antimicrobial peptide or STAMP is provided. In certain embodiments the dental varnish system comprises a first component that is a dry powder, said first component comprising a an antimicrobial peptide, with or without a fluoride, and a bulking agent, and a second component that is a fluid, said second component comprising a varnish solution, where combination of said first component with said second component provides a varnish formulation for application to the surface of a tooth.

Abstract: Disclosed are oral care compositions, for example dentifrice compositions, comprising an oral care composition comprising an orally acceptable vehicle, metal oxide particles having an average particle size of no greater than a dentin tubule and at least one amino acid capable of chelating the metal oxide. The composition may comprise a polymeric adherent material for adhering the metal oxide particles in the dentin tubule. The metal oxide particles have a median particle size of 5 microns or less, and may comprise zinc oxide.

Abstract: Dentifrice compositions comprising zinc lactate, glycine, and fluoride ion are provided for treating dental plaque biofilm.

Abstract: The present invention relates to core shell silica particles, wherein each core shell silica particle comprises a silica core, and a surface of the silica core is etched with metal silicate, the core shell silica particles prepared by: i) admixing an amount of silica particles in water with an amount of a base, wherein the base comprises a monovalent metal ion, to produce core shell silica particles, each core shell silica particle comprising a silica core, and a surface of the silica core etched with a silicate of the monovalent metal ion; and ii) reacting the core shell silica particles formed in step i) with a metal salt comprising a second metal ion, to form core shell silica particles comprising silicate of the second metal ion on the surface of the silica core.

Abstract: An oral varnish comprising a combination of two different viscosity dimethicone components, wherein the difference between the two different viscosity dimethicone components is about 2.0 million cP or greater; and comprising at least one active ingredient, which is preferably a fluoride donor.

Abstract: The present invention relates primarily to fragrance substance mixtures, preferably perfume oils, comprising or consisting of (a) 8,8-dimethyl-6,10-dioxaspiro[4,5]decane, i.e. a compound of formula (I) as described herein, and additionally (b) one or more fragrance substance(s) selected from the group consisting of esters, lactones, oximes and sulphur compounds with a molar mass of 240 g/mol or less and/or (c) one or more fragrance substance(s) selected from the group consisting of acetals, ketones and ethers with a molar mass in the range of 126-240 g/mol.

Abstract: A composition for reducing microbial activity in an environment susceptible to microbial activity, comprising: metallic nanoparticles; and an oxygenation agent.

Abstract: A fluorine coating agent having enhanced dental tubule permeability and coating endurance, and a method for preparing the same. The fluorine coating agent applied on the surface of a tooth is enhanced in abrasion resistance to increase a period of time during which a coating membrane lasts, thereby preventing dental caries. Further, the curing time of the fluorine coating agent can be controlled to allow the agent to permeate and thus block the dental tubule.

Abstract: The present invention relates to an antimicrobial polymer coating composition including: a (meth)acrylate-based monomer or oligomer containing an alkylene oxide having 1 to 10 carbon atoms; a photosensitizer; and a photoinitiator, and an antimicrobial polymer film including a substrate layer including a polymer resin containing a (meth)acrylate-based repeating unit having an introduced alkylene oxide functional group having 1 to 10 carbon atoms, and a photosensitizer dispersed in the substrate layer, wherein the antimicrobial polymer film has surface energy of 32 mN/m or more.

Abstract: A polymeric composition for enhancing grip, including a modified solvent phase and a solid phase dispersed within the modified solvent phase. The modified solvent phase may include calcium-based gel, including calcium acetate particles partially dissolved in an alcoholic solution. The solid phase also includes a polymeric matrix and a plurality of desiccant particles encompassed by the polymeric matrix. The polymeric matrix includes polyvinyl acetate (PVAc) and a thickener.

Abstract: A toothpaste composition includes a structurant and a thickener, wherein the toothpaste composition has a predetermined viscosity and phase angle by using the structurant instead of reducing the content of a thickener, and thereby has an improved release property during use while maintaining a shape retention property of the toothpaste, and has an improved feeling of refreshment, flavor releasing power, cleaning power, and stain removal power. Further, provided is a toothpaste composition including a chelating agent containing phosphate and silica, wherein the chelating agent is supersaturated to precipitate phosphate to provide strong cleaning power, a whitening effect, a stain removal effect, and a crunchy sensation. Further, provided is a toothpaste composition including a peroxide, a thickener, and a spreading agent, wherein the peroxide and the thickener are separated from each other, providing excellent sense of use, stability, and a whitening effect in an anhydrous state.