Fish Oil Or Solidified Form Thereof Patents (Class 424/523)
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Patent number: 5886037Abstract: A nutritional composition comprising fats and optionally carbohydrates, proteins and other food constituents, in which the fatty acids of the fats consist of:--55-95 wt. % n-3 polyunsaturated chain fatty acids caprylic acid and capric acid,--5-25 wt. % of the medium chain fatty acids stearidonic acid, eicosatetraenoic acid, eicosapeataenoic acid, docosapentaenoic acid and/or docosahexaenoic acid,--0-30 wt. % of other fatty acids,is suitable for treating increased plasma lipid levels in hypertriglyceridaemia or hyperchylomicronaemia.Type: GrantFiled: November 20, 1997Date of Patent: March 23, 1999Assignee: N.V. NutriciaInventors: Hans-Ulrich Bernhard Klor, Annette Hauenschild
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Patent number: 5840715Abstract: This invention is directed to a dietary regimen and a unique combination of nutritional supplements and a method. More specifically, this invention is directed to a unique combination of nutritional supplements which provides symptomatic relief from arthritis. The unique combination of nutritional supplements of this invention is believed to function by both increasing the available (effective blood level) of anti-inflammatory agents and promotion of the healing/regenerative process in the effected joints, thus producing unexpected and lasting symptomatic relief from the debilitating effects of both osteoarthritis and rheumatoid arthritis.Type: GrantFiled: January 6, 1998Date of Patent: November 24, 1998Assignee: Inholtra Investment Holdings & Trading, N.V.Inventor: Vito V. Florio
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Patent number: 5817695Abstract: A nutritional product is provided for cancer patients comprising, as per caloric requirement, a low concentration of carbohydrate, a high concentration of fat and an imbalance of amino acids wherein L-phenylalanine, L-tyrosine and L-methionine are present in the below normal concentrations and L-leucine is present in substantial excess of normal concentrations to suppress cancer growth and as an adjunct to conventional cancer therapies.Type: GrantFiled: December 24, 1997Date of Patent: October 6, 1998Inventor: Michael A. Pellico
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Patent number: 5720980Abstract: A composition for protecting a crop against fungal diseases which includes one or more fish oils used in association with an agriculturally acceptable diluent and, preferably, with a metal salt. Also provided is a method for protecting a crop against fungal diseases which includes applying to the seed or foliage of a crop or its locus, a fish oil in an amount sufficient to induce the local and/or systemic resistance of the crop to control the fungal disease.Type: GrantFiled: January 11, 1996Date of Patent: February 24, 1998Assignee: Bar-Kan UniversityInventor: Yigal Cohen
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Patent number: 5709888Abstract: The present invention provides a new fat mixture for infant and adult nutrition which possesses adequate levels and ratios of polyunsaturated fats and long chain polyunsaturated fats. These fat mixtures possess adequate levels of phospholipids and an adequate relationship between oleic acid, linoleic acid and .alpha.-linolenic acid as well as adequate levels of long chain polyunsaturated fatty acids of both the n6 and n3 series. In addition, the fat mixtures of the present invention possess an adequate ratio of arachidonic acid (20:4n6) to docosahexaenoic acid (22:6n3). These fat mixtures are modeled on the fat content of human milk for infant diets and on the mediterranean diet for adult nutritional products. Diets containing these mixtures promote the growth and development of the infant and contribute to the prevention and treatment of some diseases in adults.Type: GrantFiled: March 25, 1996Date of Patent: January 20, 1998Assignee: Abbott LaboratoriesInventors: Angel H. Gil, Jesus L. Jimenez, Jose C. Moreno
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Patent number: 5700457Abstract: A processed product for hair and skin treatment, having binary and tertiary fluid phase levels prior to remixing and therapeutic use is disclosed. The invention discloses defined amounts of admixed components including an Iodine complex having tincture of iodine solution and povidone-iodine compound, a diluting fluid complex having a water and mineral oil constituent, and a cod liver oil component, which, after admixing, are ambiently exposed to a photon-light-energy component from sunlight or substantially equivalent artificial light to produce a processed product having at least binary product reaction fluid levels and containing a nucleophically iodinated cod liver oil compound.Type: GrantFiled: May 24, 1996Date of Patent: December 23, 1997Inventor: Gary W. Dixon
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Patent number: 5650157Abstract: Some otherwise desirable oil compositions derived from natural sources are characterized by an unpleasant odor. Fractions or combinations of such oils may also be so characterized. Stable, deodorized oils may be prepared by adding an amount of a deodorizing agent effective to substantially reduce the odor of the derived oil composition, fraction or combination thereof to that oil composition, fraction or combination. The pharmaceutical topical compositions of the present invention contain these stable, deodorized oil compositions and exhibit enhanced penetration properties and achieve enhanced patient response. The improved pharmaceutical compositions of the present invention may be used to manage pain and/or to treat the underlying ailments. Methods of making such topical pharmaceutical compositions are also discussed.Type: GrantFiled: March 22, 1994Date of Patent: July 22, 1997Inventor: Barry I. Bockow
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Patent number: 5594029Abstract: The present invention relates to the use of natural or synthetic first runnings coconut fatty acid as an insect-repellent agent which is applied to human or animal skin or to clothing.Type: GrantFiled: May 11, 1995Date of Patent: January 14, 1997Assignees: Franz Bencsits, Perycut-Chemie AGInventor: Franz Bencsits
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Patent number: 5554361Abstract: A processed product for hair and skin treatment, having binary and tertiary fluid phase levels prior to remixing and therapeutic use is disclosed. The invention discloses defined amounts of admixed components including an Iodine complex having tincture of iodine solution and povidone-iodine compound, a diluting fluid complex having a water and mineral oil constituent, and a cod liver oil component, which, after admixing, are ambiently exposed to a photon-light-energy component from sunlight or substantially equivalent artificial light to produce a processed product having at least binary product reaction fluid levels and containing a nucleophically iodinated cod liver oil compound.Type: GrantFiled: January 24, 1995Date of Patent: September 10, 1996Inventor: Gary W. Dixon
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Patent number: 5494684Abstract: A composition for protecting a crop against fungal diseases which includes one or more fish oils used in association with an agriculturally acceptable diluent and, preferably, with a metal salt. Also provided is a method for protecting a crop against fungal diseases which includes applying to the seed, tuber or foliage of a crop or its locus, a fish oil in an amount sufficient to induce the local and/or systemic resistance of the crop to control the fungal disease. Preferably, the fish oil is used to protect a potato or tomato crop against infection by the late blight fungus Phytophthora infestans.Type: GrantFiled: February 23, 1994Date of Patent: February 27, 1996Assignee: Bar-Ilan UniversityInventor: Yigal Cohen
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Patent number: 5407683Abstract: Compositions of matter are provided comprising a pharmaceutically effective amount of taxol or a tumor-active analog thereof solubilized in a pharmaceutically acceptable carrier comprising an oil having a dipole moment of between about 0.5 Debyes and about 2.0 Debyes, and preferably between about 1.6 and about 1.7 Debyes. Oils from marine organisms having an ether lipid as a major component thereof are preferred. Methods of solubilizing taxol or tumor-active taxol analogs in the pharmaceutically acceptable oils of this invention are provided comprising forming a first solution by dissolving taxol in a preliminary solvent such as an anhydrous alcohol, then adding sufficient oil to solubilize said first solution. Taxol-in-oil solutions are used to prepare oil-in-water emulsions for pharmaceutical use in anti-tumor therapy by means known to the art using known surfactants.Type: GrantFiled: October 1, 1992Date of Patent: April 18, 1995Assignee: Research Corporation Technologies, Inc.Inventor: Merrick L. Shively
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Patent number: 5397565Abstract: A lotion for hooves is described that includes the following ingredients expressed as a percentage of volume. Fish oil should represent 20 to 81 percent of total volume; pine tar 1 to 45 percent; and-propylene glycerol 15 to 36 percent. The remainder of the lotion, 3 to 20 percent, should consist of a compatible emulsifying agent for maintaining pine tar in emulsion. By adjusting the proportions of ingredients the described lotion can be adapted to suit seasonal humidity.Type: GrantFiled: May 6, 1994Date of Patent: March 14, 1995Inventor: Winston Rice
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Interaction of thermal hysteresis proteins with cells and cell membranes and associated applications
Patent number: 5358931Abstract: A newly discovered property of thermal hysteresis proteins is the interaction of these proteins with cell membranes and thus with cells themselves, protecting cells and their membranes from damage which they would otherwise suffer upon exposure to non-physiological conditions such as temperature abnormalities, including both hyperthermic, hypothermic and sub-freezing temperatures. Improved rates of cell viability are observed over a wide range of conditions which do not involve ice formation, including temperatures above the freezing range as well as temperatures below the freezing range but in vitrification conditions. Heretofore the only known property of these proteins was their ability to interact with ice crystals.Type: GrantFiled: January 15, 1993Date of Patent: October 25, 1994Assignee: The Regents of the University of CaliforniaInventors: Boris Rubinsky, Arthur L. Devries, Amir Arav -
Patent number: 5130061Abstract: A process for the extraction of eicosapentaenoic (EPA) and docosahexaenoic (DHA) acid esters from crude fish oils, by means of transesterification with ethanol and H.sub.2 SO.sub.4 and two-step molecular distillation.Type: GrantFiled: May 24, 1989Date of Patent: July 14, 1992Assignee: Innova di Ridolfi Flora & C. s.a.s.Inventors: Franco Cornieri, Walter Di Fulvio
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Patent number: 5079003Abstract: Cosmetic creams or lotions comprising emulsions of shark liver oil, squalane, and squalene along with numerous other ingredients with therapeutic and synergetic effects on the skin are disclosed.Type: GrantFiled: March 14, 1990Date of Patent: January 7, 1992Inventor: Adelia Scaffidi
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Patent number: 5053387Abstract: A composition and method of treating a traumatic injury by improving immunologic response and reducing a hypermetabolic response associated with those suffering from a traumatic injury such as a substantial burn, trauma, major surgery and the like and more particularly to those suffering from a substantial thermal burn injury to the skin or other areas through the administration of the composition of the invention to those suffering from the traumatic injury are disclosed. The composition comprises an intact protein, arginine, carbohydrate, lipid comprising the omega-3 fatty acids of fish oil, including eicosapentaenoic acid, and with linoleic acid limited to the amount necessary to prevent an essential fatty acid deficiency thereof and nutritionally necessary vitamins and minerals.Type: GrantFiled: May 16, 1990Date of Patent: October 1, 1991Assignee: Shriners Hospitals for Crippled ChildrenInventor: J. Wesley Alexander
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Patent number: 5034414Abstract: A nutritional liquid emulsion for transfusion comprising of a mixture of fatty acid esters containing 20-22 carbon atoms which are contained in a purified fish oil selected from the group consisting of sardine oil, cod oil, squid oil, mackerel oil or Euphauciacea oil, of a purified soybean or safflower oil, of purified yolk lecithin or soybean lecithin and the balance water. Said nutritional liquid emulsion for transfusion is well balanced in fatty acid composition and is nutritionally valuable and also possesses antithorombotic activity and antiarteriosclerotic activity.Type: GrantFiled: May 5, 1989Date of Patent: July 23, 1991Assignee: Terumo Kabushiki KaishaInventors: Toshio Wakabayashi, Kazuo Okamoto, Akio Kanazawa
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Patent number: 5032400Abstract: Strains, sprains and sore skeletal muscles are treated with topical application of pharmaceutical composition containing a combination of shark liver oil and garlic oil in a cream or ointment base.Type: GrantFiled: November 2, 1989Date of Patent: July 16, 1991Assignee: Erie LaboratoriesInventors: Jeffery Wiersum, Henry E. Troy
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Patent number: 5006281Abstract: Marine animal oil free of undesirable odor or taste is produced by treating a freshly killed marine animal with a peroxidase-inhibiting antioxidant, disaggregating the marine animal, separating the oil phase, mixing with a dilute aqueous acidic solution, removing the oil phase and adding antioxidant. Marine animal oil which has already turned rancid may be restored to a non-rancid state by mixing with a reducing antioxidant such as a thiodipropionate, separating out the fatty acids which have reacted with the antioxidant, preferably by column chromatography, and adding another antioxidant to prevent further peroxidation.Type: GrantFiled: January 28, 1987Date of Patent: April 9, 1991Assignee: Century Laboratories, Inc.Inventors: David Rubin, Elyiahu J. Rubin
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Patent number: 5002974Abstract: A long lasting, esthetically pleasing medicated skin care moisturizing composition comprising(1) an oil phase comprising oil from about 30% to about 80% and a non-ionic surface active agent having an HLB number of about 7 to about 12, wherein the non-ionic surface active agent is present in an amount of about 5% to about 9%;(2) an aqueous phase comprising an aqueous thickening agent from about 0.05% to about 5% and water from about 15% to about 65%;(3) an effective amount of a topical medicament; wherein the oil phase is added to the aqueous phase to form an emulsion and a topical medicament admixed into the emulsion has been developed.The method of preparation of the composition and a method of treating skin with the composition are also disclosed.Type: GrantFiled: April 4, 1988Date of Patent: March 26, 1991Assignee: Warner-Lambert Co.Inventor: Navin M. Geria
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Patent number: 4992478Abstract: A long lasting, esthetically pleasing medicated skin care moisturizing composition comprising(1) an oil phase comprising oil from about 30% to about 80% and a non-ionic surface active agent having an HLB number of about 7 to about 12, wherein the non-ionic surface active agent is present in an amount of about 5% to about 9%;(2) an aqueous phase comprising an aqueous thickening agent from about 0.05% to about 5% and water from about 15% to about 65%;(3) an effective amount of a topical medicament; wherein the medicament is a corticosteroid and the oil phase is added to the aqueous phase to form an emulsion and a topical medicament admixed into the emulsion has been developed.The method of preparation of the composition and a method of treating skin with the composition are also disclosed.Type: GrantFiled: April 4, 1988Date of Patent: February 12, 1991Assignee: Warner-Lambert CompanyInventor: Navin M. Geria
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Patent number: 4992477Abstract: A long lasting, esthetically pleasing skin care moisturizing composition comprising(1) an oil phase comprising oil from about 30% to about 80% and a non-ionic surface active agent having an HLB number of about 7 to about 12, wherein the non-ionic surface active agent is present in an amount of about 5% to about 9%;(2) an aqueous phase comprising an aqueous thickening agent from about 0.05% to about 5% and water from about 15% to about 65% wherein the oil phase is added to the aqueous phase to form an emulsion has been developed. The method of preparation of the composition and a method of treating skin with the composition are also disclosed.Type: GrantFiled: April 4, 1988Date of Patent: February 12, 1991Assignee: Warner-Lambert CompanyInventor: Navin M. Geria
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Patent number: 4992476Abstract: A long lasting, esthetically pleasing skin cleansing and care moisturizing composition comprising(1) an oil phase comprising oil from about 30% to about 80% and a non-ionic surface active agent having an HLB number of about 7 to about 12, wherein the non-ionic surface active agent is present in an amount of about 5% to about 9%;(2) an aqueous phase comprising an aqueous thickening agent from about 0.05% to about 5% and water from about 15% to about 65% wherein the oil phase is added to the aqueous phase to form an emulsion has been developed,(3) an effective amount of an abrasive to remove oily deposits, cosmetics and particulates from the skin surface.The method of preparation of the composition and a method of treating skin with the composition are also disclosed.Type: GrantFiled: April 4, 1988Date of Patent: February 12, 1991Assignee: Warner-Lambert CompanyInventor: Navin M. Geria