Serum Patents (Class 424/531)
  • Patent number: 5219578
    Abstract: A method of stimulating the immune system of mammals is claimed comprising treating a second mammal with a gamma immunoglobulin containing fraction obtained from a first mammal which has not been exposed to foreign antigens.
    Type: Grant
    Filed: February 25, 1991
    Date of Patent: June 15, 1993
    Assignee: InnoVet, Inc.
    Inventor: Daniel R. Ansley
  • Patent number: 5200199
    Abstract: A method for isolating tissue repair promoting substances from human or animal blood which comprises collecting the human or animal blood from a single human or animal individual in a first container of a container system comprising at least a first and second interconnected containers; centrifuging the container system containing the blood so as to separate the blood in various fractions including a plasma fraction; transferring at least part of the plasma fraction to the second container of the container system; subjecting the plasma fraction in the second container to a low temperature so as to obtain a precipitate comprising tissue repair promoting substances; concentrating the precipitate in the second container so as to obtain a first fraction comprising a major part of the non-precipitated material; and separating the second fraction comprising the tissue repair promoting substances from said first fraction within the second container; and optionally heating the second fraction within one of the contai
    Type: Grant
    Filed: May 21, 1991
    Date of Patent: April 6, 1993
    Inventor: Ulla S. Weis-Fogh
  • Patent number: 5186945
    Abstract: The treatment of blood plasma to inactivate or destroy infective viruses, such as the cytomegalovirus CMV, by mixing the plasma with an effective amount of glycyrrhizic triterpenoid compounds is disclosed. Detergents, glycerol or ethylene diamine tetraacetic acid can be added to augment the affect of the glycyrrhizic triterpenoid compounds.
    Type: Grant
    Filed: November 7, 1989
    Date of Patent: February 16, 1993
    Inventor: Edward Shanbrom
  • Patent number: 5128150
    Abstract: The treatment of blood product to inactivate or destroy infective viruses found in animal fluids and tissues, such as the cytomegalovirus, by mixing the blood product with an effective amount of glycyrrhizic triterpenoid compounds in combination with albumin is disclosed.
    Type: Grant
    Filed: October 23, 1989
    Date of Patent: July 7, 1992
    Inventor: Edward Shanbrom
  • Patent number: 5104639
    Abstract: A method for establishing a treatment protocol for correcting an abnormal condition or disease in a living organism is described. The method comprises the steps of analyzing body fluids from normal and abnormal individuals to generate analysis patterns of the normal and abnormal fluids, comparing the patterns to determine differences in the patterns, and establishing a treatment protocol for the abnormal individual through chemical or metabolic therapy which treating will normalize the abnormal pattern.
    Type: Grant
    Filed: November 21, 1988
    Date of Patent: April 14, 1992
    Assignee: ESA, Inc.
    Inventor: Wayne R. Matson
  • Patent number: 5064645
    Abstract: The present invention relates to a serum for passive immunization of fish against furunculosis caused by Aeromonas salmonicida, which comprises antibodies against A. salmonicida isolated from fish naturally infected with furunculosis in an intraperitoneal injectable carrier. There is also provided a method for preparing a serum for passive immunization of fish against furunculosis caused by Aeromonas salmonicida, comprising the steps of: a) administering to a mammal selected from the group consisting of bovine, ovine, caprine and equine a sufficient amount of A. salmonicida to produce antibodies; b) collecting from the mammal the serum containing the antibodies against A.
    Type: Grant
    Filed: July 27, 1990
    Date of Patent: November 12, 1991
    Assignee: Pisciconsult Developpement Inc.
    Inventors: Jean-Louis Frechette, Youssef Elazhary
  • Patent number: 5057314
    Abstract: The present invention provides a low molecular weight anti-viral factors isolated from the serum of a hyperimmune regressor line chicken and methods of purifying same. The factors are useful in the treatment and prevention of certain disease states.
    Type: Grant
    Filed: June 20, 1989
    Date of Patent: October 15, 1991
    Inventors: Craig E. Whitfill, Nicholas R. Gyles, John A. Thoma
  • Patent number: 5055485
    Abstract: A process of inactivating infectious viruses in a cell-containing or a protein-containing composition containing such viruses, comprising contacting such composition with an effective amount of at least one aryl diol epoxide of the formula ##STR1## in which X is an aromatic ring system having from 3 to 6 used rings,for a sufficient period of time substantially to inactivate said viruses without incurring substantial disruption or inactivation of cells or without incurring substantial protein denaturation.
    Type: Grant
    Filed: December 2, 1988
    Date of Patent: October 8, 1991
    Assignee: New York Blood Center, Inc.
    Inventors: Nicholas E. Geacintov, Jay E. Valinsky, Bolanle Williams, Bernard Horowitz
  • Patent number: 5019402
    Abstract: There is disclosed a composition and process for disinfecting or essentially sterilizing blood fractions and components of blood. The composition is formed by adding a chlorine dioxide liberating compound with a weak organic acid and a heat activated saccharide.
    Type: Grant
    Filed: February 20, 1990
    Date of Patent: May 28, 1991
    Assignee: Alcide Corporation
    Inventors: Robert D. Kross, David I. Scheer
  • Patent number: 4994374
    Abstract: This invention relates to a method of diagnosing cancerous diseases, which comprises measuring the amount of UDP-N-acetylglucosamine:glycoprotein N-acetylglucosaminyl-transferase in body fluid and evaluating the increase in its amount for the diagnosis of hepatic diseases.AFP, CEA and .gamma.-glutamyltranspeptidase have hitherto been used as tumor markers for the diagnosis of hepatic cancer. But these conventional tumor markers show a positivity rate of about 60%, making early diagnosis almost impossible.The method of this invention employs UDP-N-acetylglucosamine:glycoprotein N-acetylglucosaminyltransferase as tumor marker, whereby early diagnosis of hepatic cancer can be made almost completely.
    Type: Grant
    Filed: May 1, 1989
    Date of Patent: February 19, 1991
    Assignee: Oriental Yeast Co., Ltd.
    Inventors: Atsushi Nishikawa, Naoyuki Taniguchi, Isamu Takagahara