Leucocyte Patents (Class 424/534)
  • Cell-separation
    Patent number: 4939081
    Abstract: A method and apparatus for separating particles by means of a contra-flow centrifuge, wherein a monitor system is used to analyze or control the separation process. The monitor system used impinges a monochromatic light beam on a sample of the separated particles, and measures the light scattering not only in the beam-forward direction, but also in the beam-reverse and beam-lateral directions. This reduces the processing time and increases the reliabiity of output data.
    Type: Grant
    Filed: May 27, 1987
    Date of Patent: July 3, 1990
    Assignee: The Netherlands Cancer Institute
    Inventors: Carl G. Figdor, Peter Sloot
  • Cell separation process
    Patent number: 4927750
    Abstract: Cell separation compositions and associated methods effective for separating cells from various biological specimens such as blood are disclosed. The biological specimens are contacted with the cell separation compositions and centrifuged. The cells are separated based upon their buoyant density in the cell separation composition. The cell separation composition contains colloidal silica particles covalently linked to an organosilane having a non-ionic, hydrophilic group.
    Type: Grant
    Filed: March 25, 1987
    Date of Patent: May 22, 1990
    Assignee: Jeanette Simpson
    Inventor: Allan R. Dorn
  • Reagent for cell separation
    Patent number: 4927749
    Abstract: Cell separation compositions and associated methods effective for separating cells from various biological specimens such as blood are disclosed. The biological specimens are contacted with the cell separation compositions and centrifuged. The cells are separated based upon their buoyant density in the cell separation composition. The cell separation composition contains colloidal silica particles covalently linked to an organosilane having a non-ionic, hydrophilic group.
    Type: Grant
    Filed: April 9, 1986
    Date of Patent: May 22, 1990
    Assignee: Jeanette Simpson
    Inventor: Allan R. Dorn
  • Stabilization of leukocytes
    Patent number: 4923797
    Abstract: Preservation of leukocytes by suspending in storage medium containing modified fluid gelatin, plasma, and a non-toxic buffer. Preferred additives include heterocyclic bases which occur in nucleic acids, or nucleosides or nucleotides containing the same.
    Type: Grant
    Filed: November 29, 1988
    Date of Patent: May 8, 1990
    Assignee: President & Fellows of Harvard College
    Inventor: Bernard M. Babior