Abstract: The present invention relates to fungicidal compositions and particularly fungicidal compositions comprising anhydrous milk fat (AMF), soybean oil and/or coconut fat. The invention also relates to a fungicidal method employing a composition of the invention. The compositions and methods of the invention have applications in the management (prevention and control) of fungal growth in commercial and small scale crop production.

Abstract: a formulation for trichological treatment of a patient including, in a dosage in the range of 3 g to 8 g: phytosterols in the range of 200 mg to 2500 mg; the quantitative equivalent of Polygonum multiflorum root 4:1 in 70% EW in the range of 600 mg to 2600 mg; methylsulfonylmethane in the range of 500 mg to 2000 mg; and bovine colostrum in the range of 500 m to 2000 m.

Abstract: A new method is described for the treatment of cancer. In one alternative, the method utilizes two main compositions. The first composition is Soma, a healing herb described in the Rig Veda, the sacred scriptures of the Hindus. The second composition is a composite of plant-derived substances and a mineral. When they are administered to cancer patients following the recommended therapeutic regimen, regression of the cancer results. Alternatively, the second composition can be used alone.

Abstract: The present invention relates to use of c-9, t-11 CLA or a salt, ester or precursor thereof or CLA-enriched milk fat comprising milk fat enriched with c-9, t-11 CLA or a salt, ester or precursor thereof for treating or preventing conditions such as those associated with one or more of leukocyte infiltration, eosinophilia, IgE secretion, airway remodelling, bronchoconstriction and mucus hypersecretion. The invention also relates to a pharmaceutical composition comprising CLA-enriched milk fat.

Abstract: The invention provides a method for the treatment of acne comprising orally administering to a person suffering from acne an effective amount of a whey protein fraction containing lactoferrin, and preferably containing further specific whey proteins. The lactoferrin is preferably native bovine lactoferrin and the whey protein fraction is administered at a level of between 10 mg and 2 g lactoferrin per patient per day.

Abstract: A method for the production of an imnmunostimulant milk product, characterized in that bioconversion is carried out on or a milk substrate with the aid of a Bifidobacterium culture by keeping said substrate in contact with said culture in conditions which are unfavorable with respect to the fermentation of Bifidobacterium. The invention also relates to milk foods and products obtained by said method.

Abstract: This invention relates to a method for treating skin damage, comprising the step of administration of a pharmaceutical or dermatological composition of basic milk factors to the area of the skin of a subject in need of such treatment. The invention further relates to a method for cosmetically treating the aged appearance of skin. The skin damage may be the result of normal biological ageing, environmental factors, dermatological disorders, medical treatments, surgical treatments and/or medical conditions. The aged appearance of skin may be attributed to wrinkles, blemishes, sagging, hyperpigmentation, changes to skin thickness and/or a rough appearance. In a preferred embodiment, the subject in need of such treatment requires the enhancement of the youthful appearance of their skin. The invention further relates to compositions for the treated of these conditions.

Abstract: The invention relates to cows capable of producing milk low in total saturated fatty acids and high in mono- and poly-unsaturated fatty acids.

Abstract: The invention relates to a nutritional composition comprising colostrum and a fat blend that is particularly suited the treatment of intestinal dysfunction in HIV patients.

Abstract: Methods for interfering with the growth of fungi by exposing the fungi to an antimicrobial agent derived from cream, and more particularly, to methods for treating human fungal pathogens such as Candida albicans and Aspergillus fumigatus, through exposing the fungi to free fatty acids with antimicrobial activity derived from cream.

Abstract: The present invention provides means and methods for obtaining an antibody in a mammary secretion product of a farm-animal comprising administering to said animal at least two compositions, which may be the same or different, comprising an antigen to which said antibody is to be raised, the method comprising administering at least a first of said compositions such that a high mucosal and/or systemic immune response is obtained and wherein at least a second of said compositions is administered to a mammary gland and/or a supramammary lymph node of said animal.

Abstract: The invention relates to the field of food compositions and their use. In particular compositions comprising at least 15 En % protein and pantothenic acid, or equivalents thereof, are provided, which are suitable for stimulating appetite.

Abstract: Compositions useful for inhibiting the growth of bacteria, including bacteria that can cause gastric ulcers, are provided. In addition, transgenic organism that can produce such compositions are provided. Methods of using the compositions to treat or prevent gastric ulcers in a subject, including a human subject, also are provided.

Abstract: A method for treating metabolic disorders or illnesses associated with metabolic disorders by administering a protein-rich nutrient concentrate as a dietetic food. Studies show that the administration of concentrate leads to highly significant normalization of numerous parameters that are considered to be risk factors or markers for cardiovascular illnesses and atherosclerosis.

Abstract: The present invention provides a novel feedstock and method of feeding dairy cows. Milk products derived from cows fed the feedstock are also encompassed. Milk comprising at least 0.3% DHA/g of fatty acids and food products containing components of that milk are also included. The milk product of the invention also contains elevated levels of DPA and EPA.

Abstract: A pharmaceutical composition for the treatment of patients with human immunodeficiency virus infection is disclosed. The composition comprises effective amounts of: components obtained from Neem (Azadirachta Indica); and a protein supplement. This composition can be produced by: contacting powdered Neem with water to allow said water to extract components from said Neem powder to produce an aqueous extract; and mixing the aqueous extract with a protein supplement to form a drink. A method for treating a patient with human immunodeficiency virus infection is also disclosed. This method can comprise the step of orally administering to said patient the drink.

Abstract: Method for obtaining an anti-tumor substance from even-toe hoofed mammals (artio-dactylous animals) having leucosis, and according to a first alternative, the substance is obtained from the lipid-free blood plasma fraction of the animal, and the blood is taken from a pregnant female donor animal being in the 2nd or 3rd period of pregnancy up to at most the beginning of the first week preceding delivery. According to a second alternative the substance is obtained from the colostrum of the female donor animal, being preferably cow or sheep.

Abstract: Disclosed is a floating sustained release pharmaceutical dosage form including a drug that is adapted to release the drug over an extended period of time. The buoyant pharmaceutical dosage form provides extended gastric residence time of the formulation so that substantially all of the drug is released in the stomach over an extended period. The pharmaceutical dosage form is formulated with low molecular weight concentrated milk proteins to provide buoyancy to the dosage form which can float in gastric fluid for an extended period, including up to about 48 hours.

Abstract: A composition is provided that provides a nutritionally complete calorically dense formula suitable for use as a ready-to-use liquid composition that does not require reconstitution and admixing, which contains intact whey protein in high concentration and which is shelf stable for up to 6 months or more at ambient temperature.

Abstract: A new method is described for the treatment of cancer. In one alternative, the method utilizes two main compositions. The first composition is Soma, a healing herb described in the Rig Veda, the sacred scriptures of the Hindus. The second composition is a composite of plant-derived substances and a mineral. When they are administered to cancer patients following the recommended therapeutic regimen, regression of the cancer results. Alternatively, the second composition can be used alone.

Abstract: The present invention relates to the use of alpha-lactalbumin in the preparation of preparations to be used in therapeutic or prophylactic treatment and/or for diagnostic use for infections, preferably of the respiratory tract, caused by bacteria, in particular S. pneumoniae and/or H. influenzae. The present invention further relates to essentially pure protein complexes comprising alpha-lactalbumin and the use of these protein complexes for therapeutically or prophylactically treating a bacterial infection, especially infections of the respiratory tract caused by S. pneumoniae and/or H. influenzae.

Abstract: The present invention provides methods that utilize compositions containing colostrinin, a constituent peptide thereof, an active analog thereof, and combinations thereof, as modulators of intracellular signaling molecules, for example.

Abstract: A milk or other dairy product, capable of minimizing the onset of disease such as coronary heart disease or enhancing the immune response is derived from animals which are substantially free of the ?-casein A1 allele. Bulk milk can be produced by testing for and culling cows who test positive for the ?-casein A1 allele, or by producing immunoglobulins and other immune response proteins, in cow's milk from animals not possessing the ?-casein A1 allele, or other commercial milk producing animals, to this allele, to counteract the immnunosuppressant substances present that are produced from it, in commercial milking cows such as Holsteins, together with its blending with non-treated milk or the recovery of such immunoproteins.

Abstract: Product R, a novel therapeutic composition for treating viral infections and stimulating the immune system, comprises a unique peptide having 31 amino acids and another unique peptide having 21 amino acids and connected with an oligo-nucleotide through a diphosphodiester or diphosphodithioate ester linkage. The composition has a light absorption spectrum with typical absorption ratios of 1.998 at 260 nm/280 nm and 1.359 at 260 nm/230 nm.

Abstract: A dietary supplement which is formulated for medical patients, particularly renal dialysis patients undergoing a peritoneal renal dialysis treatment regimen. The supplement includes a powdered mixture of calcium caseinate, whey protein, L-carnitine and arginine. The ingredients are typically formulated in a powdered form which can be easily added to and ingested with various foods. The supplement provides various nutritional benefits to renal dialysis patients, including the elevation of blood carnitine and albumin levels and the reduction of blood pressure in renal transplant patients.

Abstract: A method of treating patients having rheumatoid arthritis by administering Product R, a peptide-nucleic acid preparation, is disclosed.

Abstract: A method to improve the health and growth of suckling dairy calves on dairy farms includes supplementing calves' diets with a ruminal fluid preparation obtained from the rumen of a cow. This supplement provides the calves with the protection needed to develop faster and healthier. It also leads to a decreased incidence of scours in the treated calves.

Abstract: A composition including a bait and a borate is used to mitigate a population of target insects and/or mollusca. The composition may include attractive by-products of agriculture and manufacturing with or without semiochemicals or biopesticides prepared as point source units (such as pellets or microcapsules). The by-products attract insects and/or mollusca to a food source for the purpose of mitigating the target organism. The bait is combined with borates and is pelletized and/or encapsulated into micron size particles. The pelletized and/or encapsulated particles are broadcast (spread) over areas infested with the target insect. The insects ingest the composition and regurgitate the composition to the remainder of the insect population. Significant mitigation of the population of the target insects results with little to no effect on the environment. The composition is also passed on to the next generation due to cannibalism of the target insects.

Abstract: The invention relates to pharmaceutical or veterinary compositions for the treatment of surface wounds; pharmaceutical or veterinary compositions for the treatment of gastrointestinal injuries, diseases or ulcers; methods of treating surface wounds in animals, including humans; and methods for the treatment of gastrointestinal injuries, diseases or ulcers which compositions and methods include compositions of milk product extracts including growth factors with basic to approximately neutral isoelectric points.

Abstract: The method for increasing lactose tolerance in subjects exhibiting lactose intolerance symptoms implements a protocol where the subjects ingest a gradually increasing amount of lactose containing product over a six week period. At various points during the six week period the subject ingests the lactose containing product once a day and then twice a day. The lactose containing product can be in liquid form, such as for example, milk, and is preferably in a powder form which is taken either by ingesting capsules having the lactose powder or in a granular form mixed with water or other non-lactose containing liquid. At the end of the six week period, the subject's tolerance for lactose containing products is substantially increased, with the potential of eliminating the subject's lactose intolerant behavior indefinitely.

Abstract: The present invention provides means and methods for obtaining an antibody in a mammary secretion product of a farm-animal comprising administering to said animal at least two compositions, which may be the same or different, comprising an antigen to which said antibody is to be raised, the method comprising administering at least a first of said compositions such that a high mucosal and/or systemic immune response is obtained and wherein at least a second of said compositions is administered to a mammary gland and/or a supramammary lymph node of said animal.

Abstract: Various compositions containing transfer factor in combination with nutraceuticals are provided including transfer factor in combination with zinc and essential fatty acids and transfer factor in combination with lactic acid generating bacteria. Also provided are methods for treating animal diseases and syndromes using these compositions.

Abstract: The present invention provides methods that utilize compositions containing colostrinin, an constituent peptide thereof, an active analog thereof, and combinations thereof, as an oxidative stress regulator.

Abstract: A milk-derived basic protein fraction and a basic peptide fraction are provided for use as an effective component for agents for improving lipid metabolism and reducing high blood pressure which can be administered orally, are effective with a relatively small dosage, have good taste and are stable during storage.

Abstract: Product R, a novel therapeutic composition for treating viral infections and stimulating the immune system, comprises a unique peptide having 31 amino acids and another unique peptide having 21 amino acids and connected with an oligo-nucleotide through a diphosphodiester or diphosphodithioate ester linkage. The composition has a light absorption spectrum with typical absorption ratios of 1.998 at 260 nm/280 nm and 1.359 at 260 nm/230 nm.

Abstract: A method of producing a biological fungicide composed of milk products, namely powdered cow milk, cow milk culture or bacteria culture, and a calcium carbonate. These components can be mixed to form a mixture, stored for long-term at below 32 degrees Fahrenheit or held below 75 degrees Fahrenheit for one month. Upon application of the mixture, fulvic acid may be added to the mixture.

Abstract: Disclosed is a method of fractionating ?-lactalbumin from ?-lactoglobulin in whey or whey protein concentrate. The method includes the steps of contacting whey or whey protein concentrate with a complexing agent so that the complexing agent forms insoluble complexes with ?-lactoglobulin present in the whey or whey protein concentrate. The insoluble complexes are then separated from the whey or whey protein concentrate, thus yielding a precipitate that is predominately ?-lactoglobulin and is substantially devoid of ?-lactalbumin, and a supernatant that predominately ?-lactalbumin and is substantially devoid of ?-lactoglobulin.

Abstract: A composition for eliciting a T-cell mediated immune response in a subject includes transfer factor from at least two different types of source animals. For example, the composition may include mammalian transfer factor and nonmammalian transfer factor. An example of the composition includes a combination of a colostrum-derived product, which includes the mammalian transfer factor, and an egg-derived product, which includes the nonmammalian transfer factor. Additionally, the egg-derived product may be substantially free of fat. Methods for forming the composition and eliciting T-cell mediated immune responses in subjects that have been treated with the composition are also disclosed.

Abstract: Process for extracting beneficial compounds, in particular growth factors, such as TGF &bgr; and IGF-1 from milk. In this process a hydrophobic interaction chromatography step is included. A resin having a butyl group, or a phenyl group as the ligand is used as hydrophobic interaction resin. The resin can be eluted with a salt gradient which, when the ligand is a phenyl group, contains substantially no alcohol, and thus resulting in fractions enriched in the desired growth factors. These fractions can be separated further with a hydroxyapatite column.

Abstract: A device for the transdermal administration of a substance to an animal comprising: positioning means and delivery means. The positioning means comprising an inner and an outer surface and being configured to position and hold in place said delivery means. The delivery means comprising an inner and an outer surface and being configured to facilitate the transdermal administration of substances. The outer surface of said delivery means and said inner surface of said positioning means are attachable to each other.

Abstract: A patch for the delivery of substances to the skin of a user, said patch comprising an impermeable substrate comprising an upper and a lower surface, the lower surface comprising an adhesive configured to substantially adhere the patch to the skin of a user; and the lower surface further comprising a matrix containing such substances, the patch being characterised in that it comprises colostrum and/or a colostrum derivative and/or a multi-vitamin and mineral solution.

Abstract: A method for modification and isolation of a protein is provided. The method includes the steps of providing a protein selected from the group consisting of whey and soy proteins; providing a reagent that forms sulfite ions; mixing the protein with the reagent under a condition to sulfonate the protein without using an oxidizing agent and to obtain a mixture containing a sulfonated protein; precipitating the sulfonated protein out of the mixture at an acid pH to form a precipitated sulfonated protein and a soluble sulfonated protein; and recovering the precipitated sulfonated protein or soluble sulfonated protein.

Abstract: A process is disclosed for extracting glycomacropeptide from a lactic raw material. This process includes the step of treating a lactic raw material containing glycomacropeptide in the presence of a weakly anionic resin wherein the glycomacropeptide is selectively adsorbed onto the resin and then eluted from the resin so as to obtain an improved protein product which can be used in foods, and pharmaceutical and dental compositions.

Abstract: A dietary supplement for mammalian consumption, and particularly human consumption, for the purpose of stimulating the immune system, inhibiting infection and increasing tissue repair and healing. Comprising colostrum, lactoferrin, and with modified citrus pectin as an optional component, the dietary supplement is administered in ‘mucosal delivery format’: a dosage form that promotes effective absorption through the lining of the oral cavity.

Abstract: Treatment of menorrhagia, hypermenorrhea and dysmenorrhea by the administration of a therapeutic amount of an antibacterial milk product.

Abstract: The invention is a composition and method for non-specific enhancement of immune responses in human and animal recipients. A colostrum-derived feed additive (CDFA) for human or veterinary use comprises a sprayed-dried preparation of pasteurized and homogenized first milking colostrum that enhances immune responses in a recipient receiving an oral administration. Generally, CDFA is administered in a conditioning dose once per day during a conditioning period of time from about 7 to 14 days, and then in a maintenance dose administered once per day during a period that follows the conditioning period. The maintenance dose is about one-half the concentration of the conditioning dose. Administration of CFDA enhances immune response in a recipient in a dose-dependent manner.

Abstract: A medication for burns and wounds comprising beeswax in combination with butter and with, in most application, rosin, for providing immediate relief of pain and hastening the scabbing process. For medications with rosin, the formulation comprise 7-14% rosin, 10-50% beeswax and 50-70% butter preferably at a ratio of one part rosin, 2-4 parts beeswax, and 10-12 parts unsalted butter. All ingredients are natural and commercially available. The medication is stable at room temperature and is observed to increase its effectiveness or efficacy with storage.

Abstract: The present invention establishes a dose dependant correlation between the amount of bovine colostrum consumed as a supplement and the levels of increase of immunoglobulins and lymphocytes present in the immune system of the studied subjects. In this way the invention develops a method of enhancing the immune response in an individual by supplementation of bovine colostrum.

Abstract: The present invention pertains to a method for increasing calcium absorption and decreasing the bone loss in humans by administering to a human an effective amount of a calcium supplement in conjunction with a colostrum supplement. The supplement administered preferably comprises bovine colostrum as the colostrum supplement.

Abstract: Glutathione (GSH) is a tripeptide of extreme importance as a catalyst, reductan, and reactant. It can be depleted intra-cellularly either by forming a direct complex with an electrophilic agent (accomplished investigationally by agents such as bromobenzene or diethyl maleate), by way of inhibition of synthesis, or by subjecting cells to oxidant stress. Most cells, except for epithelia cells, do not have a direct transport capacity for intact GSH. Non-epithelial cells must either transport precursor substrates for GSH synthesis or salvage amino acids from circulating GSH for reuse in intracellular resynthesis. Dietary cysteine is a rate limiting substrate for the synthesis of glutathione and also inhibits GSH efflux. Although GSH is synthesized from precursors in virtually all cells, the liver is the main source of plasma GSH. Protection and support of liver function is paramount to elevating GSH levels.