Derived From Arthropod (e.g., Insect, Spider, Crustacea, Etc.) Patents (Class 424/538)
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Patent number: 12018100Abstract: Methods of producing a chitin composition by which the properties of the chitin composition derived from krill, such as molecular weight (chain length) and degree of acetylation are reproducible, are claimed. Such reproducible production methods allow for a wide use of the chitin composition end products in pharmaceutical and biomedical applications. The methods also allow for the production of chitin compositions which preserve the native state of chitin.Type: GrantFiled: May 24, 2022Date of Patent: June 25, 2024Assignee: RIMFROST TECHNOLOGIES ASInventor: Inge Bruheim
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Patent number: 11992020Abstract: A method of determining a measure of gaping in a fish fillet item, involves the steps of obtaining three-dimensional profile data of a first area of the fish fillet item, obtaining optical imaging data of a second area of the fish fillet item, wherein the first area and the second area are overlapping at least within an overlap area; and determining the measure of gaping in the fish fillet item based on the three-dimensional profile data within the overlap area and the optical imaging data within the overlap area.Type: GrantFiled: December 21, 2021Date of Patent: May 28, 2024Assignee: MAREL SALMON A/SInventors: Anders Kjaer, Martin Andersen
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Patent number: 11779611Abstract: An improved method for the manufacture of a medicament, which method includes the use of tissues, larval forms or derivatives of insects that have been fed on a food containing pathogens.Type: GrantFiled: July 9, 2019Date of Patent: October 10, 2023Assignee: IMMUNE MACRO-BIOTIC TECHNOLOGY UK LIMITEDInventor: Christopher Jeremy Leonard
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Patent number: 11369653Abstract: A traditional Chinese medicine composition for treating cardiovascular and cerebrovascular disease, the active ingredients thereof being composed of: 1) an ethanol extract of 6-12 parts of Ligusticum wallichii and 5-10 parts of Curcumae Radix, and 2) an aqueous extract of extract residue of the described Ligusticum wallichii and Curcumae Radix and 5-10 parts of Radix Cyathulae; the traditional Chinese medicine composition may further comprise an aqueous extract of 5-10 parts of Allium macrostemon and 6-12 parts of Eucommia ulmoides. The traditional Chinese medicine composition relates to medicine made from plant compounds, and has significant medicinal effects on myocardial contraction disorder and myocardial dilation disorder, platelet aggregation thrombosis and myocardial ischemia, myocardial hypoxia, myocardial fatigue, and so on, being particularly suitable for treating coronary heart disease and chronic or acute heart failure.Type: GrantFiled: July 23, 2018Date of Patent: June 28, 2022Inventor: Hongzhang Jia
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Patent number: 10653725Abstract: The present invention provides methods for treating and preventing viral disease in farmed fish. In particular, the present invention relates to compositions and methods for improving heart health in farmed salmon.Type: GrantFiled: August 17, 2016Date of Patent: May 19, 2020Assignees: Aker BioMarine Antarctic AS, Biomar GroupInventors: Sigve Nordrum, Harald Takle, Sven Martin Jørgensen, Trygve Sigholt
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Patent number: 9918933Abstract: The present invention discloses a medicine for treatment or adjuvant treatment of acquired immunodeficiency syndrome, a preparation method thereof and use methods thereof. The medicine comprises: lightyellow sophora root, glabrous greenbrier rhizome, bark of Chinese corktree, raw sessile stemona root, alumen, coptis root, cortex dictamni, chinaberry bark and root-bark, pangolin scales, amber, eucommia bark, tree peony bark, clematis root, common cnidium fruit, Chinese angelica, licorice root, common macrocarpium fruit, barbary wolfberry fruit, medicinal indianmulberry root, cherokee rose fruit, chinaroot greenbier rhizome, akebia fruit, milkvetch root, Japanese climbing fern spore, asiatic pennywort herb, mulberry leaf and frankincense.Type: GrantFiled: May 29, 2015Date of Patent: March 20, 2018Inventor: Darong Liu
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Patent number: 9585943Abstract: The composition for tissue/cell repair facilitates healing of damaged tissues, promoting tissue and cell growth, protecting cells and tissues, and reducing scar tissue. The composition includes hydrolyzed collagen, and may include high molecular weight hydrolyzed collagen. The hydrolyzed collagen may be combined with native collagen and/or at least one other therapeutic agent. For example, the therapeutic agent may be a polysulfated glycosaminoglycan, a glucosamine salt, or mixtures thereof. The collagen may be derived from two or more different sources, and may be combined with hydrolyzed whey and/or elastin.Type: GrantFiled: April 13, 2016Date of Patent: March 7, 2017Inventor: George D. Petito
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Patent number: 9278217Abstract: Described are methods and devices for improving diastolic function with electrostimulation in heart failure patients who exhibit relatively normal systolic function. Such patients are characterized by impaired myocardial relaxation during diastole that prevents adequate filling of the ventricles during diastole to thereby reduce cardiac output. An implantable device is described for effecting strategic and periodic stimulation of the sympathetic nervous system to elicit myocardial adrenergic activation for improved myocardial relaxation.Type: GrantFiled: July 29, 2013Date of Patent: March 8, 2016Assignee: Cardiac Pacemakers, Inc.Inventors: Allan C. Shuros, Shantha Arcot-Krishnamurthy, Guy Alvarez
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Publication number: 20150128864Abstract: The present invention in general relates to the field of biological crop protection by use of predatory mites. More particularly the present invention relates to a mite composition comprising a predatory mite and a prey. Such a mite composition is suitable for rearing the predatory mite and/or for crop protection using the predatory mite. The prey in the composition comprises individuals of at least one Astigmatid mite species, wherein at least a fraction of the Astigmatid individuals is immobilized. The composition is characterized in that immobilized Astigmatid individuals are contacted with a fungus reducing agent.Type: ApplicationFiled: October 23, 2012Publication date: May 14, 2015Inventors: Karel Jozef Florent Bolckmans, Yvonne Maria Van Houten, Adelmar Emmanuel Van Baal, Radbout Timmer, Damien Marc Morel
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Patent number: 8986660Abstract: Disclosed is a cooling component or sensate component which does not have undesirable stimulus feeling, bitterness and the like and is excellent in the persistence of refresh-feeling and cool-feeling, a sensate composition which comprises the same, and various products that comprise said sensate composition.Type: GrantFiled: October 11, 2013Date of Patent: March 24, 2015Assignee: Takasago International CorporationInventors: Kazuma Hojo, Takashi Aida, Kenya Ishida
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Publication number: 20150030689Abstract: The present invention in general relates to the field of biological crop protection by use of phytoseiid predatory mites. More particularly the present invention relates to a system for releasing a phytoseiid predatory mite in a crop and novel uses of host mites in such phytoseiid predatory mite releasing system. The phytoseiid predatory mite releasing system according to the invention and the uses according to the invention are characterised by the selection a host mite species having an intrinsic growth rate (rm) of <0.28.Type: ApplicationFiled: September 19, 2012Publication date: January 29, 2015Applicant: Koppert B.V.Inventors: Karel Jozef Florent Bolckmans, Yvonne Maria Van Houten, Adelmar Emmanuel Van Baal, Arno Theodoor Stam
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Publication number: 20150017253Abstract: The present invention relates to a composition for preventing or treating an immune-related disease, and, more specifically, relates to a composition for preventing or treating immune-related diseases or oxidative-stress-related diseases in which the toxicity of an arsenic compound is effectively suppressed while the immune function boosting effect thereof is nevertheless maximised. The composition according to the present invention is useful in preventing or treating various immune-related diseases or oxidative-stress-related diseases since the composition reduces the toxicity of arsenic compounds, which traditionally have been difficult to use in clinical practice due to toxicity, while nevertheless maximising the pharmacological effects thereof.Type: ApplicationFiled: March 27, 2013Publication date: January 15, 2015Inventors: Kyoung Yun OK, Eun Hee OK
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Publication number: 20150017252Abstract: The embodiments disclose a supplement and medication cultivated plant delivery system including using a cultivation system for cultivating integrated enriched food products including fruits, produce and aquatic species and animal feeds, controlling and testing the cultivation system environment including an aqua cultivation media, incorporating a controlled feed system to raise aquatic species and animals using integrated enriched food products feeds, harvesting cultivated integrated enriched food products and cultivated integrated enriched food products feed raised aquatic species and animals, delivering the cultivated integrated enriched food stuffs to markets for providing alternative cultivated integrated enriched food stuffs to prevent and treat health conditions on a long-term sustainable basis, and empowering people to improve their health conditions while simply eating cultivated integrated enriched food stuffs in their daily regimen of eating.Type: ApplicationFiled: July 14, 2014Publication date: January 15, 2015Inventors: Wayne Garland, Allen Mark Jones, G. Douglas Hayden
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Publication number: 20150000600Abstract: The present invention in general relates to the field of rearing of commercially relevant mites. More particularly the present invention relates to a mite composition, suitable for the commercial rearing of mites, a method for rearing mites and a rearing device using the composition of the invention, a method for crop protection using the composition according to the invention wherein the mite is selected as a predatory mite, and the use of a carrier material for rearing a mite species.Type: ApplicationFiled: October 23, 2012Publication date: January 1, 2015Inventors: Karel Jozef Florent Bolckmans, Yvonne Maria Van Houten, Adelmar Emmanuel Van Baal, Radbout Timmer, Damien Marc Morel
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Publication number: 20140369995Abstract: The present invention provides compositions and methods for treating stroke patients using TCM and a Western medicament used for the treatment of stroke patients.Type: ApplicationFiled: September 3, 2014Publication date: December 18, 2014Inventors: David Picard, Shi Xue Min, Michael Lazdunski
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Publication number: 20140335061Abstract: Disclosed are compositions and methods comprising supplemented oils for improving health, reducing cardiovascular risk factors, or treating certain conditions.Type: ApplicationFiled: December 7, 2012Publication date: November 13, 2014Applicant: METAPROTEOMICS, LLCInventors: Matthew L. Tripp, Robert H. Lerman
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Publication number: 20140322347Abstract: A medicine for treating allergic cough comprises 5 to 25 parts by weight of Perilla Leaf, 5 to 25 parts by weight of Periostracum Cicada, and 5 to 25 parts by weight of lumbricus. The medicine is in the form of concentrated decoction, tablet, pill, granule or capsule. The medicine has effects of dispelling wind-cold, dispelling wind-heat, relieving cough and preventing asthma. The medicine provides excellent anti-allergic effect and can be used for treating allergic cough.Type: ApplicationFiled: December 25, 2012Publication date: October 30, 2014Inventors: Yiwen Yan, Haocheng Yan, Zongguo Ye
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Patent number: 8828447Abstract: The present invention relates to processes for the isolation of a phospholipid and for producing a polyunsaturated, long-chain fatty acids (PUFA)-enriched fraction from a fish oil comprising the steps of —providing a fish oil containing lipids and phospholipids; —mixing the fish oil with a polar solvent; —centrifuging the mixture of the fish oil and the polar solvent to separate a polar fraction from a lipid fraction; —isolating a phospholipid from the polar fraction or isolating a PUFA-enriched fraction from the polar fraction. The fish oil may be provided by —extracting a fish material with an extractant solvent; —removing the extractant solvent to provide the fish oil; —optionally subjecting the fish oil to a solid-liquid separation. The isolated phospholipids and PUFA's may be used as additives for functional foods, as a dietary supplement and for pharmaceutical application.Type: GrantFiled: April 13, 2012Date of Patent: September 9, 2014Assignee: Polar Amega A/SInventors: Hans Otto Soerensen, Nils Christian Jensen
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Publication number: 20140178489Abstract: Fluorine being present in the exoskeleton of crustaceans, and especially krill represents a problem for using krill as a source for food, feed, food additives and/or feed additives. There has been developed a process for removing such fluorine from krill material by subjecting the krill to disintegration and to an enzymatic hydrolysis process prior to or simultaneously with a removal of the exoskeleton particles producing a fluorine-reduced product. Inherent in the disclosed process is the ability to process krill material with a high polar lipid content for producing superior quality, low fluorine, products suitable for the food and feed as well as the pharmaceutical, nutraceutical and cosmetic industry.Type: ApplicationFiled: November 7, 2013Publication date: June 26, 2014Applicant: Emerald Fisheries ASInventors: Stig Tore Kragh Jansson, Jon Reidar Ervik, Leif Grimsmo
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Publication number: 20140178490Abstract: A Biological Control Agent (BCA) system comprising processed parasitized mealybug mummies is disclosed. The processed and modified parasitized mealybug mummies are essentially devoid of their limbs and waxy covering. In the novel BCA system the modified parasitized mealybug mummies are processed in a manner that strips off their waxy covering and detaches their limbs without impacting on their viability as a host for parasitoid pupae. The modified parasitized mealybug mummies of the BCA system are encased in specially adapted packaging for delivering and distributing the modified parasitized mealybug mummies to plants with mealybug infestations. A method of preparing and storing the modified parasitized mealybug mummies as a BCA is also presented.Type: ApplicationFiled: May 10, 2012Publication date: June 26, 2014Inventors: Shimon Steinberg, Eyal Erel
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Patent number: 8758829Abstract: The present invention relates to a process for removing fluorine from krill material by subjecting the krill to disintegration and to an enzymatic hydrolysis process prior to or simultaneously with a removal of the exoskeleton particles producing a fluorine-reduced product. The process of the invention can process krill material with a high polar lipid content for producing superior quality, low fluorine, products suitable for the food and feed as well as the pharmaceutical, nutraceutical and cosmetic industry.Type: GrantFiled: September 14, 2009Date of Patent: June 24, 2014Assignee: Emerald Fisheries ASInventors: Stig Tore Kragh Jansson, Jon Reidar Ervik, Leif Grimsmo
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Patent number: 8728533Abstract: Provided is a formulation containing amorphous or microcrystalline calcium carbonate finely interspersed with organic matter in a ratio of 10 parts of the carbonate per 1 to 3 parts of the organic matter, wherein the organic matter consists of chitin and polypeptide. The formulation is efficient in treating various pathological conditions, including proliferative diseases, neurological disorders, and musculoskeletal disorders.Type: GrantFiled: December 27, 2012Date of Patent: May 20, 2014Assignees: Ben-Gurion University of the Negev Research and Development AuthorityInventors: Yossi Ben, Amir Sagi
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Patent number: 8728531Abstract: A composition and method which improves blood lipid profiles and optionally reduces low density lipoprotein (LDL) per-oxidation in humans by administering a therapeutic amount of a composition comprising krill oil in combination with astaxanthin or a mixture of fish oil derived, choline based, phospholipid bound omega-3 fatty acid mixture including phospholipid bound polyunsaturated EPA and DHA. In one embodiment, the krill oil is derived from Euphasia spp., comprising Eicosapentaenoic (EPA) and Docosahexaenoic (DHA) fatty acids in the form of triacylglycerides and phospholipids. The krill oil includes at least 10% EPA and 5% DHA, of which greater than 50% are in the form of phospholipids and the 1-4000 mg of krill oil per daily dose is delivered.Type: GrantFiled: May 14, 2013Date of Patent: May 20, 2014Assignee: U.S. Nutraceuticals, LLCInventors: John A. Minatelli, W. Stephen Hill, Rudi E. Moerck
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Patent number: 8722106Abstract: A lip balm composition of natural ingredients, comprising: 54-70 wt. % of one or more oils, 22-28 wt. % beeswax, 3-4 wt. % propolis, 3-5 wt. % pomace, 0.02-3.2 wt. % antioxidant, and optional ingredients, whereby all components add to 100 wt. %.Type: GrantFiled: December 2, 2011Date of Patent: May 13, 2014Assignee: The MotherVine Nutraceuticals Co. LLCInventor: Fountain Odom
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Publication number: 20140105999Abstract: This invention relates to an oil composition, preferably obtained from a copepod, and the use thereof to reduce accumulation of visceral fat and counteract impairment of heart function caused by obesity inducing Western diets. The oil composition of the present invention can thus be used to reduce abdominal obesity and improve glucose tolerance and thus to reduce the risk of obesity related diseases such as but not limited to type 2 diabetes or cardiovascular disease, or to prevent or treat such diseases.Type: ApplicationFiled: December 27, 2013Publication date: April 17, 2014Applicant: Calanus ASInventors: Jan Raa, Gunnar Rorstad, Kurt Steinar Tande
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Patent number: 8697138Abstract: This invention discloses methods of using krill oil and compositions comprising krill oil to treat risk factors for metabolic, cardiovascular, and inflammatory disorders. The present invention also relates to methods of using compositions comprising krill oil to modulate biological processes selected from the group consisting of glucose metabolism, lipid biosynthesis, fatty acid metabolism, cholesterol biosynthesis, and the mitochondrial respiratory chain. The present invention further includes pharmaceutical and/or nutraceutical formulations made from krill oil, methods of making such formulations, and methods of administering them to treat risk factors for metabolic, cardiovascular, and inflammatory disorders.Type: GrantFiled: May 28, 2010Date of Patent: April 15, 2014Assignee: Aker Biomarine ASInventors: Inge Bruheim, Snorre Tilseth, Jeffery Cohn, Mikko Griinari, Daniele Mancinelli, Nils Hoem, Hogne Vik, Sebastiano Banni
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Publication number: 20140086998Abstract: Provided herein are piperidine alkaloids and uses thereof in neurological disorders and physical enhancement applications.Type: ApplicationFiled: August 15, 2013Publication date: March 27, 2014Applicant: SYNAPSIN PHARMACEUTICALS, INC.Inventors: DENIS DORSEY, MARK S. KINDY
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Patent number: 8663704Abstract: A composition and method which improves blood lipid profiles and optionally reduces low density lipoprotein (LDL) per-oxidation in humans by administering a therapeutic amount of a composition comprising krill oil in combination with astaxanthin or a mixture of fish oil derived, choline based, phospholipid bound omega-3 fatty acid mixture including phospholipid bound polyunsaturated EPA and DHA. In one embodiment, the krill oil is derived from Euphasia spp., comprising Eicosapentaenoic (EPA) and Docosahexaenoic (DHA) fatty acids in the form of triacylglycerides and phospholipids. The krill oil includes at least 10% EPA and 5% DHA, of which greater than 50% are in the form of phospholipids and the 1-4000 mg of krill oil per daily dose is delivered.Type: GrantFiled: April 25, 2011Date of Patent: March 4, 2014Assignee: U.S. Nutraceuticals, LLCInventors: John A. Minatelli, W. Stephen Hill, Rudi E. Moerck
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Patent number: 8658688Abstract: The novel active compound combinations consisting, firstly, of cyclic ketoenois and, secondly, of beneficial species (natural enemies) have very good insecticidal and/or acaricidal properties.Type: GrantFiled: May 30, 2012Date of Patent: February 25, 2014Assignee: Bayer CropScience AGInventors: Reiner Fischer, Heike Hungenberg, Ralf Nauen, Hans-Jürgen Schnorbach, Wolfgang Thielert
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Patent number: 8586009Abstract: Disclosed is a method for producing (3S)-l-menthyl 3-hydroxybutyrate of the following formula (I) by subjecting l-menthyl acetoacetate to asymmetric hydrogenation. The compound may be used as a cooling component or sensate component which does not have undesirable stimulus feeling, bitterness and the like and is excellent in the persistence of refresh-feeling and cool-feeling.Type: GrantFiled: August 31, 2012Date of Patent: November 19, 2013Assignee: Takasago International CorporationInventors: Kazuma Hojo, Takashi Aida, Kenya Ishida
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Patent number: 8557297Abstract: The present invention contemplates the creation of a low fluoride oil processed from a phospholipid-protein complex (PPC) formed immediately upon a crustacean (i.e., for example, krill) catch. The process comprises disintegrating the crustaceans into smaller particles, adding water, heating the result, adding enzyme(s) to hydrolyze the disintegrated material, deactivating the enzyme(s), removing solids from the enzymatically processed material to reduce fluoride content of the material, separating and drying the PPC material. Then, using extraction with supercritical CO2 and ethanol as solvents, inter alia krill oil is separated from the PPC. In the extraction the krill oil can be separated almost wholly from the feed material. The products have low fluoride content. The manufacturing costs in the extraction process are relatively low.Type: GrantFiled: January 3, 2012Date of Patent: October 15, 2013Assignee: Olympic Seafood, ASInventors: Inge Bruheim, Mikko Griinari, Jon Reidar Ervik, Stig Rune Remoy
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Publication number: 20130202714Abstract: The present invention relates to a mite composition, the rearing thereof and to the use of the composition for controlling crop pests. The invention provides a mite composition comprising: a rearing population of a phytoseiid predatory mite species, a population of at least one species from the order Astigmata, and optionally a carrier, wherein the population of the species from the order Astigmata is not alive. In particular the population of the species from the order Astigmata is in fast frozen form. The composition is used for controlling crop pests, such as thrip species. The crops may be greenhouse grown crops and open field crops.Type: ApplicationFiled: April 22, 2011Publication date: August 8, 2013Applicant: AGROBÍO S.L.Inventors: Enrique Vila Rifà, Don Griffiths
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Patent number: 8491909Abstract: The present invention comprises methods and compositions for immunotherapy. An aspect of the invention comprises administration of one or more allergens in compositions via oral and sublingual routes. Allergen compositions are administered in dosing intervals wherein the increase in the one or more allergens administered to the patient are provided in increasing volumes of a single concentration of at least one allergen.Type: GrantFiled: February 7, 2005Date of Patent: July 23, 2013Assignee: Greer Laboratories, Inc.Inventor: Robert E. Esch
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Publication number: 20130156861Abstract: The present invention relates to an alcoholic injury mitigating agent comprising krill oil as an active ingredient. The krill oil preferably comprises phospholipids in an amount of at least 30% by weight, ?3 polyunsaturated fatty acids in an amount of at least 5% by weight of the total fatty acids, eicosapentaenoic acid in an amount of at least 2% by weight of the total fatty acids, or docosahexaenoic acid in an amount of at least 1% by weight of the total fatty acids.Type: ApplicationFiled: September 1, 2011Publication date: June 20, 2013Applicant: NIPPON SUISAN KAISHA, LTD.Inventors: Junichiro Hata, Tomoko Tsuji, Kenichi Yanagimoto
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Patent number: 8460890Abstract: This invention provides compositions and methods for detection of hematophagous ectoparasitic activity in an enclosure or area. The compositions comprise a reagent or reagents which are reactive against antigens or markers as they appear in the excrement or other ectoparasitic materials. Such markers or antigens may be produced by the ectoparasite itself or may have been introduced into the ectoparasite because of its blood feeding activity. The method of the present invention comprises collecting from the enclosure or area, a sample comprising environmental dust or materials and subjecting the sample to tests for detecting the presence of hematophagous ectoparasitic markers, host markers or both.Type: GrantFiled: May 28, 2010Date of Patent: June 11, 2013Assignee: Cytosignet, Inc.Inventor: Nathan L. Smith
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Publication number: 20130108706Abstract: The present invention relates to the field of nutritional support for individuals and reducing the effects of muscle conditions caused by high levels of physical activity. In particular, the invention provides dietary formulations, compositions comprising these formulations and uses of these compositions to support the body's muscle regeneration process.Type: ApplicationFiled: June 6, 2011Publication date: May 2, 2013Inventor: Katja Svennevig
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Patent number: 8399026Abstract: The presently described subject matter relates to isolated spider venom peptides, which are used as potent and selective ion channel blockers, and to a composition and methods for treatment of pain.Type: GrantFiled: September 14, 2010Date of Patent: March 19, 2013Assignee: Alomone Preclinical Ltd.Inventors: Alon Meir, Ronit Simcha Cherki, Ela Kolb, Yael Langut, Nissim Bajayo
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Publication number: 20130052273Abstract: The present invention relates to Periplaneta Americana or its ethanol extract for the treatment of inflammation. Specifically, said inflammation includes cervical erosion, ulcerative colitis, skin ulcer, mucosal ulcer and postoperative condyloma acuminatum. Treating said disorders by Periplaneta Americana or its ethanol extract has the advantages of effectively reducing bleeding, shortering healing time, significant curative effect, no adverse reactions and low cost. Periplaneta Americana or its ethanol extract provides a new selection for the clinical treatment of cervical erosion, ulcerative colitis and postoperative condyloma acuminatum.Type: ApplicationFiled: October 26, 2012Publication date: February 28, 2013Inventor: Funeng GENG
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Patent number: 8383162Abstract: Methods and compositions for blocking calcium channels with a spider toxin from Phoneutria nigriventer are provided. For easy identification the toxin will be sometimes generally referred to as Ph?-1B herein. The toxin comprises a 55-amino acid sequence having a molecular weight of approximately 6,017. This Ph?-1B spider toxin was found to block calcium channels within the nervous system. The synthetic gene responsible for producing this toxin has been designed and cloned. This gene and/or its derivative provide a mechanism by which the toxin can be produced using recombinant DNA expression technologies. The present invention further relates to methods of treating neurological diseases and pain by applying the isolated and identified toxins. The toxin Ph?-1B may provide beneficial effects on pain and certain neurological conditions including seizures, ischemic- hypoxic, CNS damage, and neurodegenerative disorders. It was also found that the toxins are effective as tags in probing calcium channels.Type: GrantFiled: November 21, 2007Date of Patent: February 26, 2013Assignee: Universidade Federal de Minas GeraisInventors: Marcus Vinícius Gómez, Marco Antônio Máximo Prado, Vânia Ferreira Prado
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Publication number: 20130004582Abstract: Beneficial and synergistic effects for alleviating joint pain and symptoms of osteoarthritis and/or rheumatoid arthritis have been found with krill oil and/or marine oil in combination with other active constituents, including astaxanthin and polymeric hyaluronic acid or sodium hyaluronate (hyaluronan) in an oral dosage form.Type: ApplicationFiled: September 11, 2012Publication date: January 3, 2013Applicant: U.S. NUTRACEUTICALS, LLC d/b/a Valensa InternationalInventors: John A. Minatelli, W. Stephen Hill, Swati Sebastian Thomas, Lingan Rajendran, Rudi E. Moerck
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Patent number: 8287913Abstract: An apparatus and method for the extraction of material from glands of arthropods. The apparatus comprises a container in which at least part of the glands are placed and a buffer solution at least partially immersing the glands. Gland material is collected in the material collection area of container. In use the material is released from glands into the buffer solution and sedimented at the bottom of the container. The method comprises: a first step of removing from a body of the arthropod the gland containing at least partially the material; a second step of making an opening in an epithelium of the gland; and a third step of placing the gland in a container at least partially immersed in a buffer solution such that the materials exit the glands and sediments in the material collection area of the container.Type: GrantFiled: May 28, 2008Date of Patent: October 16, 2012Assignee: Spin'Tec Engineering GmbHInventors: Michael Rheinnecker, Stefan Kohlhaas, Rolf Zimmat
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Publication number: 20120237609Abstract: The novel active compound combinations consisting, firstly, of cyclic ketoenois and, secondly, of beneficial species (natural enemies) have very good insecticidal and/or acaricidal properties.Type: ApplicationFiled: May 30, 2012Publication date: September 20, 2012Applicant: Bayer CropScience AGInventors: Reiner FISCHER, Heike Hungenberg, Ralf Nauen, Hans-Jürgen Schnorbach, Wolfgang Thielert
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Publication number: 20120225018Abstract: The present invention relates to compositions including a homeopathic aqueous substance active (HASA) and at least one hydrophilic gelling agent, the HASA comprises a homeopathic compound at a potency of 30 C or higher and an uninhibited aqueous composition. The present invention also relates to methods of preparing a hydrophilic HASA-gel matrix. The method includes combining a homeopathic compound and an uninhibited aqueous composition to produce a HASA; combining the HASA with at least one hydrophilic gelling agent; and thereafter, forming the hydrophilic HASA-gel matrix by use of at least one of a thickening agent, a crosslinking agent, or a polymerization agent.Type: ApplicationFiled: March 2, 2012Publication date: September 6, 2012Inventor: Nancy Josephine Polich
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Patent number: 8227439Abstract: The present invention is directed to methods and methods for the treatment, inhibition and/or reduction, and detection of metastatic tumors. In some embodiments, the inventive methods include systemic (e.g., intravenous) administration of a chlorotoxin agent that may or may not be labeled. In some embodiments, the inventive methods allow treatment, inhibition and/or reduction, and detection of metastases in the brain. In some embodiments, neovascularization is inhibited and/or newly formed vessels are caused to regress.Type: GrantFiled: May 15, 2009Date of Patent: July 24, 2012Assignee: Morphotek, Inc.Inventors: Alison O'Neill, Douglas B. Jacoby, Abdellah Sentissi, Kamala Kesavan, E. Michael Egan, Laura Sen, legal representative
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Publication number: 20120093942Abstract: Disclosed is a pharmaceutical composition and health food comprising herb extracts of one or more herbs selected from the group consisting of Puerariae Radix, Bombycis corpus and Araliae Continentalis Radix. The herb medicine of this invention comprising a single or mixed composition may be useful for the prevention and treatment of renal diseases as well as improvement of renal functions.Type: ApplicationFiled: December 22, 2011Publication date: April 19, 2012Applicant: Dong Wha Pharm. Co., Ltd.Inventors: Jei-Man RYU, Moon-Jung LEEM, Yang-Kook ROH, Hwan-Bong CHANG, Seong-Jun OH, Hyun-Yong LEE, Sae-Kwang KU, Hee-Bog YANG, Jung-Woo RHEE, Yun-Jung KIM, Joo Byoung YOON
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Publication number: 20120070407Abstract: There is disclosed the use of a composition for promoting neuronal growth of neurons in tissues of the central or peripheral nervous system. There is also disclosed a method for inducing proliferation or differentiation of neuronal cells.Type: ApplicationFiled: March 29, 2010Publication date: March 22, 2012Inventors: Michel Maurice Jacques Lazdunski, Catherine Louise Heurteaux, David Picard
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Patent number: 8105633Abstract: Apparatus and method for the extraction of material from glands of arthropods. The apparatus includes a container in which at least part of the glands are placed and a buffer solution at least partially immersing the glands. Gland material is collected in the material collection area of the container, e.g., by release of the material from the glands into the buffer solution and sedimentation of the material at the bottom of the container. The method involves removing from a body of the arthropod the gland containing at least partially the material, making an opening in an epithelium of the gland, and placing the gland in the container at least partially immersed in a buffer solution, so that the material exits the glands and sediments in the material collection area of the container.Type: GrantFiled: June 18, 2009Date of Patent: January 31, 2012Assignee: Spintec Engineering GmbHInventors: Michael Rheinnecker, Stefan Kohlhaas, Rolf Zimmat
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Patent number: 8097285Abstract: The purpose is to prevent, ameliorate or relieve various conditions induced in the dried oral cavity or to improve the stability of a denture during use. A solution for treating a denture or a denture stabilizer comprising sericin can be used.Type: GrantFiled: August 23, 2010Date of Patent: January 17, 2012Assignee: Seiren Co., Ltd.Inventors: Yoichi Kato, Kazuhisa Tsujimoto, Hideyuki Yamada, Taizo Hamada, Sadayuki Yuda, Koichi Okano
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Publication number: 20110268813Abstract: Disclosed is a composition with anti-oxidative, anti-aging and liver-function improvement activities containing ENA actimineral resource A activated water. More specifically, disclosed are a pharmaceutical composition and a health food or health supplement containing, as an active ingredient, an alkaline ENA actimineral resource A activated water prepared from Sepia bone and red algae powders, for preventing aging due to inhibitory activity on decrease in serum vitamin C, or preventing liver damage or improving liver functions due to inhibitory activity on damage, apotosis or necrosis of hepatic cells. The composition inhibits a decrease in in vivo serum vitamin C, to inhibit aging and prevents damage, apotosis or necrosis of hepatic cells, and fundamentally protects liver cells to inhibit damage, apotosis or necrosis of hepatic cells by aging in the liver and improve liver function.Type: ApplicationFiled: September 17, 2009Publication date: November 3, 2011Inventors: Sung Yong Hwa, Kyu Shik Jeong, Jin Kyu Park, Jung Youn Han
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Publication number: 20110229582Abstract: The present invention relates to active ingredient combinations which are composed of a known dihydrofuranone derivative on the one hand and of other known active pesticidal ingredients on the other hand, and are suitable for controlling animal pests from the families of the Aleyrodidae, Thripidae, Psyllidae and Agromyzidae, and also, more particularly, from the order of the Acari. The invention also relates to combinations which consist of the abovementioned active ingredient combinations on the one hand and of beneficial species on the other hand and which are suitable for controlling animal pests.Type: ApplicationFiled: January 20, 2011Publication date: September 22, 2011Applicant: Bayer CropScience AGInventors: Reiner Fischer, Veronica Companys, Estuardo Jara Dominguez, Heike Hungenberg, Peter Meisner