Pituitary Gland Patents (Class 424/565)
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Patent number: 9649393Abstract: The disclosure provides, in part, fluorocarbon imaging reagents and methods for image-guided treatment and/or diagnosis of a subject with a condition associated with an inflammatory response in an internal organ. The disclosure additionally provides methods for image-guided treatment of myocardial infarction (MI) in a subject.Type: GrantFiled: September 17, 2013Date of Patent: May 16, 2017Assignees: University of Pittsburgh-of the Commonwealth System of Higher Education, Carnegie Mellon UniversityInventors: Eric T. Ahrens, David Schwartzman
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Patent number: 8124131Abstract: A safe and widely-applicable food intake regulator can be provided by using at least one of a fish brain and parts thereof, which have the activity to regulate suppress food intake.Type: GrantFiled: March 4, 2009Date of Patent: February 28, 2012Assignee: Maruha Nichiro Foods, Inc.Inventors: Hiroyuki Enari, Masataka Kawarasaki
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Publication number: 20090226535Abstract: A safe and widely-applicable food intake regulator can be provided by using at least one of a fish brain and parts thereof, which have the activity to regulate suppress food intake.Type: ApplicationFiled: March 4, 2009Publication date: September 10, 2009Applicant: MARUHA NICHIRO FOODS, INC.Inventors: Hiroyuki ENARI, Masataka KAWARASAKI
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Patent number: 6265383Abstract: The present invention is based on the unexpected discoveries that hypothalamic inhibitory factor (HIF) has a positive inotropic effect in a whole organ preparation, such as an isolated perfused heart, and that HIF, to a greater extent than ouabain, dilates the coronary arteries in the isolated perfused heart as manifested in increased coronary flow in hearts treated with HIP. The present invention relates to a method for increasing coronary perfusion in a mammalian host comprising administering to the host in need thereof an effective amount of hypothalamic inhibitory factor (HIF). The invention also relates to a method for producing an increased coronary vasodilatory effect in a mammalian host comprising administering to a mammalian host in need thereof an effective amount of HIF. The method of the present invention can be used to prevent and/or treat ischemic cardiac malfunction and coronary artery restenosis.Type: GrantFiled: June 7, 1999Date of Patent: July 24, 2001Assignee: The General Hospital CorporationInventor: Garner T. Haupert, Jr.
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Patent number: 6238706Abstract: A method of administering growth hormone includes (a) osmotically shocking aquatic animals for about 60 seconds with a hyperosmotic salt solution; and (b) placing the shocked aquatic animals in a tank containing a solution of about 300 mg/l of growth hormone (preferably bST). The treatment solution is preferably at least slightly saline. The aquatic animals are immersed in the treatment solution for between about 30 minutes and about two hours. The growth hormone solution is supersaturated with oxygen to place the aquatic animals in a state of suspended animation. Depending on the aquatic species treated, the osmotic salt solution and the treatment solution may be refrigerated. The aquatic animals are preferably treated when less than 24 hours old.Type: GrantFiled: October 26, 1999Date of Patent: May 29, 2001Assignee: GroFish L.L.C.Inventor: Leonard Sonnenschein
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Patent number: 6054142Abstract: A biocompatible cell device having an internal foam scaffold to provide a growth surface for encapsulated cells which produce a biologically active molecule.Type: GrantFiled: August 1, 1996Date of Patent: April 25, 2000Assignee: Cyto Therapeutics, Inc.Inventors: Rebecca Li, Tyrone F. Hazlett
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Patent number: 5811074Abstract: A diagnostic protocol and kit for evaluating pituitary growth hormone (GH) secretory capability as a means to identify the etiology of GH deficiency in children and adults is disclosed. The inventive protocol includes measuring GH secretion, provoked by independent, sequential administration of the xenobiotic GH releasing hexapeptide (GHRP-6) or any of its peptidyl or non-peptidyl synthetic analogues (GHRX) that release GH by the same cellular mechanism as GHRP-6 followed by the naturally occurring GH releasing hormone or its analogues (GHRH) to children and adults afflicted with disorders related to GH deficiency. After evaluating the effects of independent, sequential administration of the GH secretagogues upon changes in blood GH concentrations, the effect of the co-administered GH secretagogues on blood GH concentrations in the child or adult subject is then measured.Type: GrantFiled: September 30, 1996Date of Patent: September 22, 1998Assignee: University of South FloridaInventors: Barry B. Bercu, Richard F. Walker
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Patent number: 5547940Abstract: The invention describes how known peptide POMC.sub.76-103 can be used to stimulate colon cell proliferation. The peptide can be used alone, or in combination with other cell proliferation stimulating agents.Type: GrantFiled: February 28, 1994Date of Patent: August 20, 1996Assignee: Ludwig Institute for Cancer ResearchInventors: Edouard C. Nice, Robert James, Richard J. Simpson, Antony W. Burgess, Robert H. Whitehead
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Patent number: 5198216Abstract: A composition for enhancing the performance of animals, such as horses or dogs, is composed of adrenal and pituitary raw tissue concentrates, vitamin C, bioflavonoid complex, pantothenic acid, methionine, choline, vitamin B1, vitamin B2, vitamin B6, niacinamide, magnesium, vitamin B12, folic acid and organic iodine. The composition is adapted to be orally administered to an animal, is composed of all natural substances, and the relative proportions of the components are approximately:at least 40 parts adrenal raw tissue concentrate toat least 2 parts pituitary raw tissue concentrate to30-60 parts vitamin C to20-30 parts magnesium to10-20 parts of each of pantothenic acid, methionine and choline to8-15 parts of each of niacinamide and bioflavonoid complex to1-5 parts of each of vitamins B1, B2 and B6 to0.1-1 parts organic iodine to0.05-0.5 parts folic acid.Type: GrantFiled: July 30, 1990Date of Patent: March 30, 1993Assignee: Daliff CorporationInventor: David M. McGee
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Patent number: 5156851Abstract: Solid dosage forms of bioactive materials for parenteral administration such as porcine or bovine somatotropin pellets intended for subcutaneous implantation to improve food production of farm animals are coated with polyvinyl alcohol to extend the release characteristics of the material. The polyvinyl alcohol preferably has a molecular weight of from about 20,000 to 100,000, a degree of hydrolysis of at least about 98%, and is applied from an aqueous solution by spray coating to form a continuous uniform covering having a weight of from about 3 to 25 ug/mm.sup.2.Type: GrantFiled: September 19, 1991Date of Patent: October 20, 1992Assignee: Monsanto CompanyInventors: Ernesto J. Castillo, Kenneth E. Eigenberg, Kanaiyalal R. Patel, Milton J. Sabacky
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Patent number: 5017560Abstract: Porcine prolactin (pPRL) is administered to poultry in dosages of from about 1-500 ug/kg/day, preferably 10-100 ug/kg/day, to promote growth by improving the rate of weight gain and/or increasing feed utilization efficiency.Type: GrantFiled: November 6, 1987Date of Patent: May 21, 1991Assignee: Pitman-Moore, Inc.Inventors: Chauncey D. Baldwin, Brian R. Shricker, Richard E. Ivy
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Patent number: 4980166Abstract: A method of inducing or increasing ovulation in female animals which method includes administering to the animal an effective amount of a ruminant follicle-stimulating hormone, (as hereinbefore defined).Type: GrantFiled: April 30, 1987Date of Patent: December 25, 1990Assignee: Bunge (Australia) Pty. Ltd.Inventor: Malcolm R. Brandon
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Patent number: 4959354Abstract: The mixturex of FSH ( follicle stimulating hormone) and LH ( luteinizing horomone) being extracted from pig hypophyses in a definite ratio, improve to an optimum level the induction of super-ovulation in bred animals.Type: GrantFiled: July 14, 1987Date of Patent: September 25, 1990Assignee: Istituto Farmacologico Serono S.p.A.Inventor: Manlio Barbetti