Calcium Carbonate Patents (Class 424/687)
  • Patent number: 10946075
    Abstract: Radioprotection, Radiomitigation and Radiorecovery: Timed use of more widely available antiradiation agents in a kit for subjects affected by ionizing radiation, radiomimetic exposure and radiocontamination. The method in the form of strategically timed preemptive and postirradiation compositions; radioprotection, radiomitigation and radiorecovery formulations are comprised of various available anticorporation, antioxidant, decorporation, multi-mechanistic, pro-survival, pro-hematopoietic, anti-fibrotic and other novel ingredients in synergistic mixtures to be used in critically-timed manners.
    Type: Grant
    Filed: February 14, 2018
    Date of Patent: March 16, 2021
    Inventor: Suzanne J Paxton-Pierson
  • Patent number: 10813378
    Abstract: The invention relates to substance mixtures which contain (a) sodium carboxymethyl cellulose and (b) at least one bitter principle selected from the group consisting of xanthines, phenolic glycosides, flavanoid glycosides, hydrolysable or non-hydrolysable tannins, flavones and the glycosides thereof, caffeic acid and the esters thereof, terpenoid bitter principles, catechin, epicatechin, epigallocatechin, gallocatechin, gallocatechin-3-gallate, leucine, isoleucine, valine, tryptophan and phenylalanine, protein hydrolysates, peptides and metal salts and their mixtures, and optionally (c) dextrins, with the proviso that the components (a) and (b) are in the weight ratio of from 1:1 to 1:1,000.
    Type: Grant
    Filed: June 3, 2015
    Date of Patent: October 27, 2020
    Assignee: SYMRISE AG
    Inventors: Sabine Widder, Kathrin Langer, Gerhard Krammer, Olga Pauli, Cornelia Homner
  • Patent number: 10800817
    Abstract: A method for treating a cancer comprises administering to a subject in need of such treatment an effective amount of a pharmaceutical composition comprising an anti-cancer agent having at least one secretion modifying region (SMR) peptide from HIV-1 Nef fused to at least one cell-penetrating peptide (CPP) or at least one Clusterin (Clu)-binding peptide (Clu-BP).
    Type: Grant
    Filed: December 19, 2018
    Date of Patent: October 13, 2020
    Assignee: MOREHOUSE SCHOOL OF MEDICINE
    Inventors: Vincent C. Bond, James W. Lillard, Jr., Ming Bo Huang
  • Patent number: 10792296
    Abstract: A dry formulation may include one or more active agents including one or more anti-infective agents such as an anti-bacterial agent, anti-fungal agent, or other anti-active agent. The dry formulation may be prepared for administration by mixing the dry formulation with a diluent. In one example, the diluent is a hydrocortisone and acetic acid solution or a sodium chloride solution. The combined preparation may be administered to the ear or skin to treat or prevent an infection.
    Type: Grant
    Filed: October 7, 2019
    Date of Patent: October 6, 2020
    Assignee: CMPD LICENSING, LLC
    Inventor: Jay Richard Ray, II
  • Patent number: 10758566
    Abstract: Stabilized amorphous calcium carbonate (ACC) for treatment of several neurological, muscular and infertility diseases and conditions is provided. In particular, the stabilized ACC may be used in the treatment of axonal defects and muscular dystrophy. In addition, provided are improved methods used in assistant reproductive technology. Examples of such methods are in vitro fertilization and improvement of sperm quality. The improved IVF method, for example, comprises addition of the stabilized ACC to the cell culture medium in which the stages of fertilization and embryo development occurs.
    Type: Grant
    Filed: January 17, 2017
    Date of Patent: September 1, 2020
    Assignee: AMORPHICAL LTD.
    Inventors: Yosef Ben, Abraham Shahar, Amir Arav
  • Patent number: 10076549
    Abstract: The invention provides novel compositions that can be used as a supplement (e.g. feed supplement) to animals such as, horses. In certain embodiments, the composition comprises an effective amount of a preparation obtained from sea buckthorn and an effective amount of an amino acid. In other embodiments, the composition includes specific combinations of components selected from the group of a preparation obtained from sea buckthorn, glutamine, aloe vera extract, pectin, and lecithin. The invention also provides methods and uses of the composition for alleviating, treating or preventing an ulcer-related condition in a subject identified in need thereof.
    Type: Grant
    Filed: November 28, 2012
    Date of Patent: September 18, 2018
    Assignee: SmartPak Equine LLC
    Inventors: Jessica Normand, Kerri Vuolo, Lydia Gray, Paal C. Gisholt, Michael Uckele, Jack Grogan, Kevin Isley
  • Patent number: 9351501
    Abstract: Methods and compositions for a lipid-based food filling including a lipid system, and particulates having a size of about 30 micrometers or less, the particulates having a lipophilic surface, wherein the filling has a water activity of less than about 0.3 and wherein substantially no fat separates from the filling when the filling is heated to temperatures of up to about 200° F.
    Type: Grant
    Filed: December 12, 2011
    Date of Patent: May 31, 2016
    Assignee: INTERCONTINENTAL GREAT BRANDS LLC
    Inventors: Richard Couttenye, James Schulok
  • Patent number: 9293237
    Abstract: Use of 2-aminoethanol as an additive in an aqueous suspension, containing from 25 to 62 vol. % of at least one calcium carbonate-comprising material, wherein the use provides improved stability with regard to the conductivity of the suspension.
    Type: Grant
    Filed: May 31, 2011
    Date of Patent: March 22, 2016
    Assignee: Omya International AG
    Inventors: Matthias Buri, Samuel Rentsch, Patrick A. C. Gane
  • Publication number: 20150110881
    Abstract: A pharmaceutical composition for use in oral medication for the treatment of diabetes mellitus can include an antacid agent with an enteric coating, which permits the antacid agent to be delivered in the small intestine where it reduces acidity thereby causing a lowering of blood sugar levels. The pharmaceutical composition can be packaged in various tablet forms, including standard tablets and multiple pellet tablets. The pharmaceutical composition can further include a composition for treatment of diabetes, such as metformin, in enteric or non-enteric formulations. The pharmaceutical composition can further include an enteric-coated gastric acid secretion inhibitor. Also disclosed are methods for the treatment of diabetes mellitus, using the pharmaceutical composition and its variants.
    Type: Application
    Filed: December 22, 2014
    Publication date: April 23, 2015
    Inventors: Kenneth John Tibbs, Dawn Ann Tibbs
  • Publication number: 20150104424
    Abstract: Compositions and methods are provided for improving the health of an animal by reducing certain diseases and by binding certain heavy metals that may be unintentionally introduced into the body of the animal from the environment. Compositions and methods are also provided for improving the feed conversion ratio of an animal. In addition, compositions and methods are provided for reducing nitrate pollution in the environment. In one embodiment, the composition may include mastic gum, a mixture of ionic minerals, and optionally an essential amino acid not produced by the animal. The ionic minerals may be derived from water sourced from an inland sea such as the Great Salt Lake, the Dead Sea, or another inland sea. The essential amino acid may be included in the form of a protein. The animal may be a ruminant, poultry, or other animal. Methods are also provided for processing mastic gum.
    Type: Application
    Filed: October 14, 2014
    Publication date: April 16, 2015
    Inventors: Joseph Scivoletto, Steven Adelstein
  • Patent number: 8992953
    Abstract: Cosmetic compositions in the form of an emulsion having at least one aqueous phase and at least one fatty phase, the fatty phase having at least one vegetable oil, and the composition having at least one volatile solvent of C9 to C15 volatile linear alkane(s) type and at least one calcium carbonate.
    Type: Grant
    Filed: July 17, 2009
    Date of Patent: March 31, 2015
    Assignee: L'Oreal
    Inventors: Euriel Clavel, Pascal Arnaud
  • Patent number: 8993002
    Abstract: Highly compactable granulations and methods for preparing highly compactable granulations are disclosed. More particularly, highly compactable calcium carbonate granulations are disclosed. The granulations comprise powdered materials such as calcium carbonate that have small median particle sizes. The disclosed granulations are useful in pharmaceutical and nutraceutical tableting and provide smaller tablet sizes upon compression than previously available.
    Type: Grant
    Filed: September 19, 2014
    Date of Patent: March 31, 2015
    Assignee: Delavau LLC
    Inventors: Kevin W. Lang, James W. Dibble, Raya Levin, Gregory B. Murphy
  • Patent number: 8968795
    Abstract: Highly compactable granulations and methods for preparing highly compactable granulations are disclosed. More particularly, highly compactable calcium carbonate granulations are disclosed. The granulations comprise powdered materials such as calcium carbonate that have small median particle sizes. The disclosed granulations are useful in pharmaceutical and nutraceutical tableting and provide smaller tablet sizes upon compression than previously available.
    Type: Grant
    Filed: April 20, 2012
    Date of Patent: March 3, 2015
    Assignee: Delavau LLC
    Inventors: Kevin W. Lang, James W. Dibble, Raya Levin, Gregory B. Murphy
  • Publication number: 20150056306
    Abstract: Provided are methods for treating calcium malabsorption and conditions associated with calcium malabsorption, employing the administration of a composition containing stable amorphous calcium carbonate. Further provided are methods for increasing bone mineral density in a bone metabolism associated disorders, diseases or conditions, employing the administration of said composition in combination with a bone resorption inhibitor.
    Type: Application
    Filed: December 13, 2012
    Publication date: February 26, 2015
    Inventors: Amir Sagi, Assaf Shechter, Galit Shaltiel-Gold, Michal Daniely, Oren Meiron
  • Publication number: 20150056262
    Abstract: This invention provides coral-based scaffolds for cartilage repair, and instruments for insertion and utilization of same within a site of cartilage repair.
    Type: Application
    Filed: July 1, 2014
    Publication date: February 26, 2015
    Inventors: Nir Altschuler, Razi Vago
  • Publication number: 20150050353
    Abstract: Calcium-containing compounds have been at least partly film-coated and/or granulated with a water-soluble substance and a water-soluble polymeric substance and use of such coated compounds in pharmaceutical compositions. The at least partly film-coated and/or granulated calcium-containing compounds have proved suitable for the preparation of tablets having a very high load of elemental calcium and a conveniently small size. A drug load of about 96% or more is obtained in tablets of the invention that have sufficient mechanical and organoleptic properties.
    Type: Application
    Filed: August 29, 2014
    Publication date: February 19, 2015
    Inventor: Jan Yngvar Piene
  • Publication number: 20150037438
    Abstract: An oral pharmaceutical composition in unit dose form, each unit dose comprising a lipophilic drug substance within a unitary carrier body, said body comprising a soft, chewable, gelled oil-in-water emulsion.
    Type: Application
    Filed: October 15, 2014
    Publication date: February 5, 2015
    Inventors: Tore SETERNES, Kurt Ingar Draget, Ingvild Johanne Haug
  • Patent number: 8940319
    Abstract: The present invention is directed to compositions, devices, and methods for non-irritatively treating and preventing mucositis, such as chronic rhinosinusitis (CRS). Some aspects of the invention concern compositions comprising or consisting essentially of sodium phosphate buffer (e.g., sodium phosphate dibasic and sodium phosphate monobasic) and calcium carbonate; mucoadministration devices and kits containing such compositions; and methods for treating or preventing mucositis conditions such as CRS, comprising mucoadministering a composition of the invention to a subject in need thereof.
    Type: Grant
    Filed: June 1, 2012
    Date of Patent: January 27, 2015
    Assignee: Accentia Biopharmceuticals, Inc.
    Inventors: Francis E. O'Donnell, Angelos M. Stergiou
  • Publication number: 20150024016
    Abstract: This invention discloses a novel class of skincare products to remove iron in the skin and its preparation method. The core active components, termed as de-ironizing inducers (DII), consist of a reducing agent and a precipitating agent. The reducing agent is selected from vitamin C, vitamin E, glutathione, vitamin A, vitamin D and their derivatives. The precipitating agent is chosen from calcium carbonate, pearl powder, magnesium carbonate, barium carbonate, calcium phosphate, magnesium phosphate, barium phosphate, calcium silicate, magnesium silicate, and barium silicate. Molar ratios of the reducing agent with the precipitating agent range from 1:3-6 and the core components in the skin care product range from 5% to 10% w/w. The PH value of the skincare product is between 6.6 and 7.4. The skin care products can safely and effectively remove iron in the skin, which has been shown to accelerate skin's natural aging and photoaging.
    Type: Application
    Filed: February 22, 2013
    Publication date: January 22, 2015
    Inventor: Xi Huang
  • Publication number: 20150004230
    Abstract: Highly compactable granulations and methods for preparing highly compactable granulations are disclosed. More particularly, highly compactable calcium carbonate granulations are disclosed. The granulations comprise powdered materials such as calcium carbonate that have small median particle sizes. The disclosed granulations are useful in pharmaceutical and nutraceutical tableting and provide smaller tablet sizes upon compression than previously available.
    Type: Application
    Filed: September 19, 2014
    Publication date: January 1, 2015
    Inventors: Kevin W. Lang, James W. Dibble, Raya Levin, Gregory B. Murphy
  • Patent number: 8906411
    Abstract: A pre-compacted materiel comprising one or more calcium-containing compounds and one or more sugar alcohols, wherein the calcium-containing compound having a polycrystallic porous structure. The pre-compacted material is preferably obtained by roller compaction and is suitable for use in the further processing of the pre-compacted material into composition like e.g. tablets.
    Type: Grant
    Filed: December 7, 2006
    Date of Patent: December 9, 2014
    Assignee: Takeda Nycomed AS
    Inventors: Poul Egon Bertelsen, Peder Mohr Olsen
  • Patent number: 8900642
    Abstract: Highly compactable granulations and methods for preparing highly compactable granulations are disclosed. More particularly, highly compactable calcium carbonate granulations are disclosed. The granulations comprise powdered materials such as calcium carbonate that have small median particle sizes. The disclosed granulations are useful in pharmaceutical and nutraceutical tableting and provide smaller tablet sizes upon compression than previously available.
    Type: Grant
    Filed: April 16, 2012
    Date of Patent: December 2, 2014
    Assignee: Delavau LLC
    Inventors: Kevin W. Lang, James W. Dibble, Raya Levin, Gregory B. Murphy
  • Publication number: 20140341963
    Abstract: A composition comprising at least one substance coated with an agent wherein the agent forms a liquid impermeable but gas permeable layer surrounding the said substance and preventing the passage of the said substance through said coating, wherein in-use the said substance is not released into solution in the body, and wherein said substance is selected from one or more of the group consisting of calcium phosphate, sodium chloride, potassium chloride, magnesium chloride, calcium carbonate, and sodium bicarbonate for use in the treatment of osteoporosis and other bone conditions.
    Type: Application
    Filed: May 9, 2014
    Publication date: November 20, 2014
    Applicant: ActiveSignal Holding Limited
    Inventor: Ward Warren
  • Patent number: 8883223
    Abstract: Highly compactable granulations and methods for preparing highly compactable granulations are disclosed. More particularly, highly compactable calcium carbonate granulations are disclosed. The granulations comprise powdered materials such as calcium carbonate that have small median particle sizes. The disclosed granulations are useful in pharmaceutical and nutraceutical tableting and provide smaller tablet sizes upon compression than previously available.
    Type: Grant
    Filed: January 15, 2014
    Date of Patent: November 11, 2014
    Assignee: Delavau LLC
    Inventors: Kevin W. Lang, James W. Dibble, Raya Levin, Gregory B. Murphy
  • Publication number: 20140322322
    Abstract: The present invention provides a pharmaceutical and/or veterinary composition comprising a retard release formulation of a Solarium glaucophyllum preparation. The composition further preferably comprises a calcium source. The composition of the invention is suitable to prevent and/or treat hypocalcaemia. Furthermore, the composition is suitable to prevent milk fever in cows. Advantageously, the composition is administered only once before calving so as to prevent the occurrence of mil fever in cows.
    Type: Application
    Filed: February 4, 2014
    Publication date: October 30, 2014
    Applicant: HERBONIS AG
    Inventors: Heinrich Bachmann, Walter Rambeck
  • Patent number: 8865767
    Abstract: A Nutritional Supplement Composition promoting the increase, development, elevation and activation of the brain chemical “serotonin” in the “subjects” brain chemistry to improve mood, thought, emotions and, mental stability and functioning comprised of the constituents, Omega 3, Omega 6, Calcium Magnesium, and B-complex is described, as well as the method of administration, the usefulness of the present invention, and who would benefit from the administration of this present invention. This Nutritional Supplement composition may be used for all, in “age appropriate” dosages for different age “subjects”. This Nutritional Supplement Composition when administered daily will reduce and stabilize the “subjects” depression, anxiety, obsessive- compulsive behaviors stress related and other emotional and mental conditions. The above statement about the embodiment of the present invention will be further explained in more specific detail in the body of the description.
    Type: Grant
    Filed: August 29, 2011
    Date of Patent: October 21, 2014
    Inventor: Sheila M Cooperman
  • Patent number: 8859011
    Abstract: Compositions comprising calcium carbonate and processes for making such compositions are provided. The invention provides a granulation comprising about 95% to about 99% by weight calcium carbonate, about 0.5% to about 5% by weight of a binder and about 0.03% to about 3% by weight of a porosity increasing agent. A pharmaceutical or nutritional composition prepared from such a granulation comprises about 90% to about 99% by weight calcium carbonate, about 0.03% to about 3% by weight of a porosity increasing agent, and about 1% to about 10% by weight of other excipients. The composition provides a smaller tablet than conventional calcium carbonate compositions, for improved ease of swallowing.
    Type: Grant
    Filed: May 10, 2007
    Date of Patent: October 14, 2014
    Assignee: Particle Dynamics International, LLC
    Inventors: Denis Stotler, Steven R. Freebersyser, R. Saul Levinson
  • Publication number: 20140262006
    Abstract: A method for producing a polymer film includes: obtaining a load graph representing a functional relationship between a weight percentage of tissue forming nanoparticles in a polymer film and a maximum load of that polymer film; obtaining a stress graph representing a functional relationship between the weight percentage of tissue forming nanoparticles in a polymer film and maximum stress of that polymer film; determining a first weight percentage corresponding to a peak of the load graph and determining a second weight percentage corresponding to a peak of the stress graph; determining an optimal weight percentage based on the first and second weight percentage values; and producing a polymer film having tissue forming nanoparticles at the optimal weight percentage.
    Type: Application
    Filed: July 22, 2013
    Publication date: September 18, 2014
    Applicant: Board of Trustees of the University of Arkansas
    Inventor: Alexandru S. Biris
  • Patent number: 8821942
    Abstract: A calcium carbonate granulation and a method for preparing a calcium carbonate granulation are provided. The method includes applying an atomized binder to powdered calcium carbonate in a fluid bed granulator at a relatively high atomization pressure to achieve a reduced binder droplet size, and drying the resulting composition at elevated temperatures in a fluidized bed dryer. The resulting granulation include porous granules having a lower density and reduced mean particle size with improved compressibility. In addition, the resulting granulation can be compacted into tablets having a hardness 50% greater than the hardness of tablets formed from commercially available granulations.
    Type: Grant
    Filed: April 5, 2012
    Date of Patent: September 2, 2014
    Assignee: Access Business Group International LLC
    Inventors: David S. Chang, Huoy-Jiun Jean Wang
  • Patent number: 8821946
    Abstract: Highly compactable granulations and methods for preparing highly compactable granulations are disclosed. More particularly, highly compactable calcium carbonate granulations are disclosed. The granulations comprise powdered materials such as calcium carbonate that have small median particle sizes. The disclosed granulations are useful in pharmaceutical and nutraceutical tableting and provide smaller tablet sizes upon compression than previously available.
    Type: Grant
    Filed: April 20, 2012
    Date of Patent: September 2, 2014
    Assignee: Delavau L.L.C.
    Inventors: Kevin W. Lang, James W. Dibble, Raya Levin, Gregory B. Murphy
  • Publication number: 20140242160
    Abstract: An oral dosage form for administration to an animal comprising a biologically utilizable form of calcium and an extended release system that maintains the calcium level in the animal's bloodstream at a substantially beneficial level for a defined period of time.
    Type: Application
    Filed: May 7, 2014
    Publication date: August 28, 2014
    Applicant: BAYER HEALTHCARE LLC
    Inventors: Pradnya BEKE, Ashish PATEL, Stephanie Petaway-Hickson
  • Patent number: 8815302
    Abstract: Highly compactable granulations and methods for preparing highly compactable granulations are disclosed. More particularly, highly compactable calcium carbonate granulations are disclosed. The granulations comprise powdered materials such as calcium carbonate that have small median particle sizes. The disclosed granulations are useful in pharmaceutical and nutraceutical tableting and provide smaller tablet sizes upon compression than previously available.
    Type: Grant
    Filed: April 20, 2012
    Date of Patent: August 26, 2014
    Assignee: Delavau LLC
    Inventors: Kevin W. Lang, James W. Dibble, Raya Levin, Gregory B. Murphy
  • Patent number: 8808735
    Abstract: The present invention relates to a novel process for the preparation of a granulate comprising a calcium-containing compound as an active substance. The method comprises a method for the preparation of a granulate comprising a calcium-containing compound as an active substance, the method comprising, i) feeding a granulation chamber with a composition comprising the calcium-containing compound, ii) wet-massing the composition with a granulation liquid optionally comprising a pharmaceutically acceptable binder for a time period of at the most 30 sec to obtain a wet granulate, iii) drying the thus obtained wet granulate. A granulate obtained by the present method is especially suitable in the preparation of solid dosage forms, in particular in the preparation of tablets.
    Type: Grant
    Filed: February 2, 2006
    Date of Patent: August 19, 2014
    Assignee: Takeda Nycomed AS
    Inventors: Poul Egon Bertelsen, Peder Mohr Olsen, Carsten Martini Nielsen, Magnus Wilhelm Tolleshaug
  • Patent number: 8808774
    Abstract: The described pKa process creates a unique combination of active ingredients. The calcium carbonate carrier is impregnated with various proportions of active ingredients and the compounds are made more effective by the sheer and absorption action as they are combined in the described process. The calcium carrier is adjusted to incorporate small amounts of highly efficient/effective pH adjusters. No natural solution exists in Nature with a pH of 10.6 that is optimal for adjusting the pKa naturally in foods. The present invention effects a change in the pKa of most acids and therefore impacts pH which can positively affect flavor, color and taste. The reduced moisture process in combination with the invention solution applied as a treatment results in fruits and vegetables that exhibit cleaner flavors, better texture, enhanced color and lower microbial counts than is found in standard IQF vegetables currently available.
    Type: Grant
    Filed: June 17, 2006
    Date of Patent: August 19, 2014
    Assignee: Scientific Food Solutions, LLC
    Inventors: Ricky L. Falkenberg, Harold L. Archibald, Danford Wilkinson, Lisa L. Trexler
  • Patent number: 8802160
    Abstract: Provided are compositions containing amorphous calcium carbonate (ACC), and at least one phosphorylated amino acid which stabilizes the amorphous form of said calcium carbonate. The compositions are useful in pharmaceutical and nutraceutical formulations.
    Type: Grant
    Filed: October 22, 2008
    Date of Patent: August 12, 2014
    Assignee: Amorphical Ltd.
    Inventors: Shmuel Bentov, Amir Sagi, Amir Berman, Assaf Shechter
  • Patent number: 8790713
    Abstract: Highly compactable granulations and methods for preparing highly compactable granulations are disclosed. More particularly, highly compactable calcium carbonate granulations are disclosed. The granulations comprise powdered materials such as calcium carbonate that have small median particle sizes. The disclosed granulations are useful in pharmaceutical and nutraceutical tableting and provide smaller tablet sizes upon compression than previously available.
    Type: Grant
    Filed: April 20, 2012
    Date of Patent: July 29, 2014
    Assignee: Delavau, L.L.C.
    Inventors: Kevin W. Lang, James W. Dibble, Raya Levin, Gregory B. Murphy
  • Patent number: 8784902
    Abstract: Highly compactable granulations and methods for preparing highly compactable granulations are disclosed. More particularly, highly compactable calcium carbonate granulations are disclosed. The granulations comprise powdered materials such as calcium carbonate that have small median particle sizes. The disclosed granulations are useful in pharmaceutical and nutraceutical tableting and provide smaller tablet sizes upon compression than previously available.
    Type: Grant
    Filed: April 20, 2012
    Date of Patent: July 22, 2014
    Assignee: Delavau L.L.C.
    Inventors: Kevin W. Lang, James W. Dibble, Raya Levin, Gregory B. Murphy
  • Patent number: 8765180
    Abstract: A white coloring composition comprising calcium carbonate as a white pigment. It may be used in the manufacture of food and pharmaceutical products.
    Type: Grant
    Filed: December 28, 2009
    Date of Patent: July 1, 2014
    Assignee: Chr. Hansen A/S
    Inventor: Klaus Koehler
  • Publication number: 20140170235
    Abstract: Described herein are biocompatible compositions that contain a copolymer and a filler material. In particular, described herein are compositions that include a copolymer and a filler which may be a calcium salt. Also described herein are methods in which the compositions are used to attach soft tissue to bone.
    Type: Application
    Filed: August 27, 2013
    Publication date: June 19, 2014
    Inventors: Nicholas John COTTON, Melissa Jane EGAN
  • Publication number: 20140171545
    Abstract: Enhanced fillers for plastics, their preparation and their use in plastic products imparting antimicrobial properties and improved tensile strength and other physical properties are presented.
    Type: Application
    Filed: March 15, 2013
    Publication date: June 19, 2014
    Applicant: Contact Marketing Solutions Innovative Technologies
    Inventor: Contact Marketing Solutions Innovative Technologies
  • Publication number: 20140170106
    Abstract: The methods and compositions disclosed herein are effective in the promoting the reattachment of delaminated cartilage to bone. The methods (and related compositions) comprise the removal of the acellular layer of the delaminated cartilage thereby exposing the underlying chondrocyte cells thereby allowing the promotion of the reattachment of the delaminated cartilage.
    Type: Application
    Filed: November 8, 2013
    Publication date: June 19, 2014
    Inventors: Kelsey Jean Carvell, Ruth Cheng, Graham Smith, Drew Burdon
  • Patent number: 8747912
    Abstract: A drug delivery system for the controlled release of a pharmaceutically-active compound by oral route comprises an intercalate of a layered double hydroxide having, before intercalation, layers of metal hydroxides, and having intercalated therein a pharmaceutically-active compound having at least one anionic group. A preferred layered double hydroxide is one that has layers which comprise [LiAl2(OH)6]+. The drug delivery system has use in the delivery of drugs such as 4-biphenylacetic acid, Diclofenac, Gemfibrozil, Ibuprofen, Naproxen, 2-Propylpentanoic acid and Tolfenamic acid.
    Type: Grant
    Filed: January 28, 2008
    Date of Patent: June 10, 2014
    Assignee: Isis Innovation Limited
    Inventor: Dermot Michael O'Hare
  • Patent number: 8741355
    Abstract: Highly compactable granulations and methods for preparing highly compactable granulations are disclosed. More particularly, highly compactable calcium carbonate granulations are disclosed. The granulations comprise powdered materials such as calcium carbonate that have small median particle sizes. The disclosed granulations are useful in pharmaceutical and nutraceutical tableting and provide smaller tablet sizes upon compression than previously available.
    Type: Grant
    Filed: April 20, 2012
    Date of Patent: June 3, 2014
    Assignee: Delavau L.L.C.
    Inventors: Kevin W. Lang, James W. Dibble, Raya Levin, Gregory B. Murphy
  • Publication number: 20140147521
    Abstract: There is provided a residual mouth alcohol inhibitor configured as an oral composition that absorbs residual mouth alcohol that remains in the mouth of an individual following the consumption of alcohol. The oral composition comprises a combination of sodium bicarbonate, calcium carbonate, parsley, kelp, fructose, citric acid, natural flavors, artificial flavors, maltodextrin, and silicon dioxide whereby the ratio of sodium bicarbonate to calcium bicarbonate in the composition is approximately 1:1 and the ratio of sodium bicarbonate to parsley in the composition is approximately 2:1 and the ratio of parsley to kelp in the composition is approximately 4:1.
    Type: Application
    Filed: February 14, 2013
    Publication date: May 29, 2014
    Applicant: Breathalyzer Equalizer, LLC
    Inventor: McCoy Moretz
  • Patent number: 8728538
    Abstract: Highly compactable granulations and methods for preparing highly compactable granulations are disclosed. More particularly, highly compactable calcium carbonate granulations are disclosed. The granulations comprise powdered materials such as calcium carbonate that have small median particle sizes. The disclosed granulations are useful in pharmaceutical and nutraceutical tableting and provide smaller tablet sizes upon compression than previously available.
    Type: Grant
    Filed: April 20, 2012
    Date of Patent: May 20, 2014
    Assignee: Delavau L.L.C.
    Inventors: Kevin W. Lang, James W. Dibble, Raya Levin, Gregory B. Murphy
  • Publication number: 20140134251
    Abstract: The present invention relates to pharmaceutical formulations for treating a respiratory tract infection or a pulmonary disease in an individual, comprising a calcium salt and a sodium salt, wherein the ratio of Ca+2 to Na+ is from about 4:1 (mole:mole) to about 16:1 (mole:mole). The invention also relates to methods of treating (including prophylactically treating) and reducing the spread of a respiratory tract infection, methods of treating (including prophylactically treating) a pulmonary disease or an acute exacerbation of a pulmonary disease, and methods of reducing the spread of an acute exacerbation of a pulmonary disease, comprising administering a pharmaceutical formulation that comprises a calcium salt and a sodium salt.
    Type: Application
    Filed: October 23, 2013
    Publication date: May 15, 2014
    Applicant: PULMATRIX, INC.
    Inventors: Michael M. LIPP, Robert W. CLARKE, David L. HAVA, Richard BATYCKY, John HANRAHAN
  • Publication number: 20140127296
    Abstract: A pharmaceutical composition for use in oral medication for the treatment of diabetes mellitus can include an antacid agent with an enteric coating, which permits the antacid agent to be delivered in the small intestines where it reduces acidity thereby causing a lowering of blood sugar levels. The pharmaceutical composition can be packaged in various tablet forms, including standard tablets and multiple pellet tablets. The pharmaceutical composition can further include an enteric coated gastric acid secretion inhibitor. Also disclosed is a method for the treatment of diabetes mellitus.
    Type: Application
    Filed: October 29, 2013
    Publication date: May 8, 2014
    Inventors: Kenneth John Tibbs, Dawn Ann Tibbs
  • Publication number: 20140127293
    Abstract: Highly compactable granulations and methods for preparing highly compactable granulations are disclosed. More particularly, highly compactable calcium carbonate granulations are disclosed. The granulations comprise powdered materials such as calcium carbonate that have small median particle sizes. The disclosed granulations are useful in pharmaceutical and nutraceutical tableting and provide smaller tablet sizes upon compression than previously available.
    Type: Application
    Filed: January 15, 2014
    Publication date: May 8, 2014
    Applicant: DELAVAU L.L.C.
    Inventors: Kevin W. Lang, James W. Dibble, Raya Levin, Gregory B. Murphy
  • Patent number: 8709499
    Abstract: Highly compactable granulations and methods for preparing highly compactable granulations are disclosed. More particularly, highly compactable calcium carbonate granulations are disclosed. The granulations comprise powdered materials such as calcium carbonate that have small median particle sizes. The disclosed granulations are useful in pharmaceutical and nutraceutical tableting and provide smaller tablet sizes upon compression than previously available.
    Type: Grant
    Filed: April 20, 2012
    Date of Patent: April 29, 2014
    Assignee: Delavau L.L.C.
    Inventors: Kevin W. Lang, James W. Dibble, Raya Levin, Gregory B. Murphy
  • Patent number: 8703210
    Abstract: A human consumable chemical compound of calcium carbonate which is coated with an impervious coating that will not allow the compound to dissolve from stomach acid but does allow it to dissolve in the aqueous environment of the intestine. The chemical compound is time released, and is positionally sensitive to reach the intestines of the human body where it is absorbed into the blood. Carbonic acid in the blood reacts upon the gradual dissolution of the compound and this reaction converts the calcium carbonate to calcium bicarbonate. Calcium bicarbonate in the blood neutralizes the body's harmful acidic wastes and is a substitute for drinking about fifty ounces of alkaline drinking water daily.
    Type: Grant
    Filed: August 10, 2005
    Date of Patent: April 22, 2014
    Assignee: Sang Lads, Inc.
    Inventor: Sang Y. Whang