Inorganic Active Ingredient Containing Patents (Class 424/600)
  • Patent number: 10888593
    Abstract: Disclosed are compositions and methods that include or utilize plant growth promoting rhizobacteria (PGPR) for improving growth and health in plants and animals. The compositions and methods include or utilize a plant growth promoting rhizobacteria (PGPR) that expresses a protein associated with pectin metabolism, and a saccharide comprising pectin or a pectin-related saccharide.
    Type: Grant
    Filed: March 30, 2017
    Date of Patent: January 12, 2021
    Assignee: AUBURN UNIVERSITY
    Inventors: Mark R. Liles, Joseph Kloepper
  • Patent number: 10863762
    Abstract: The technology relates to nutritional supplements containing one or more minerals. In particular the technology relates to nutritional supplements comprising filamentous fungal biomass and one or more minerals selected from zinc, magnesium, selenium, chromium, copper and manganese, and a process to make the nutritional supplements.
    Type: Grant
    Filed: February 25, 2016
    Date of Patent: December 15, 2020
    Assignee: CURA GLOBAL HEALTH (BVI) LIMITED
    Inventors: J. Bruce Wicking, Yilin Bian, Anbin Pu, Kathleen Mary Petersen
  • Patent number: 10744188
    Abstract: An improved manufacturing process produces microcrystalline hydroxyapatite with sustained gradual calcium release that avoids spiking in blood calcium levels. Although the improved material did not cause significant elevation of blood calcium, it was just as effective in promoting bone mineralization as conventional calcium supplements. In addition, the material has much higher levels of bone growth factors as compared to prior hydroxyapatite products.
    Type: Grant
    Filed: April 20, 2018
    Date of Patent: August 18, 2020
    Assignee: Waitaki Biosciences
    Inventors: Craig Lachlan McIntosh, Susan Finderup, Harold Garthwaite
  • Patent number: 10729132
    Abstract: A method for controlling xylophages (e.g., termites, Asian Beetle, Emerald Ash borer, Weevils, Deathwatch Caterpillars, cockroaches) by inhibiting methane production of methanogenic Archaea in the digestive tract thereof. The inhibiting of the critical biochemical pathways specific to the methanogenic Archaea is achieved by contacting the xylophage with one or more antimethanogenic reagent (AMR) compounds. The AMRs may include, for example, naturally-occurring statins (which may be found in red yeast rice) or derivatives thereof, linoleic acid or related compounds, essential oils, certain synthetic compounds or combinations thereof. As a result, the effectiveness of the methanogenic Archaea to produce methane is compromised. This subsequently results into the malfunctioning of the xylophages' digestive system and provides a safe, natural, green and sustainable means of controlling the xylophages.
    Type: Grant
    Filed: November 29, 2017
    Date of Patent: August 4, 2020
    Assignee: Environmetal Intellectual Property, Inc.
    Inventors: James Mueller, Michael Scalzi, Antonis Karachalios
  • Patent number: 10702562
    Abstract: The invention relates to probiotic bacteria and particularly, although not exclusively, to anti-bacterial compositions derived from probiotic bacteria. Disclosed are compositions comprising material secreted from probiotic bacteria, uses thereof, and methods using the compositions. Particularly contemplated are compositions comprising material secreted from Lactobacillus rhamnosus, and uses thereof.
    Type: Grant
    Filed: May 26, 2015
    Date of Patent: July 7, 2020
    Assignee: Skinbiotherapeutics PLC
    Inventors: Catherine O'Neill, Andrew McBain
  • Patent number: 10688138
    Abstract: The present invention relates to conjugated linoleic acid (CLA)-producing strains of probiotic bacteria. In particular, the present invention relates to a selection of bacterial strains belonging to the genus Bifidobacterium which were selected for their ability to produce conjugated linoleic acid (CLA) from linoleic acid (LA). Furthermore, the present invention relates to a food, dietetic or pharmaceutical composition comprising said bacterial strains capable of increasing the quantity of CLA in situ, i.e. inside the gastrointestinal tract.
    Type: Grant
    Filed: October 23, 2017
    Date of Patent: June 23, 2020
    Assignee: ALCE NORTH AMERICA, INC.
    Inventors: Giovanni Mogna, Gian Paolo Strozzi, Marco Pane
  • Patent number: 10660335
    Abstract: The present invention relates to a plant disease control agent containing a compound represented by the following formula (1) or salt thereof as an active ingredient (in the formula, R1 and R2 represents a hydrogen atom or methyl group but excepting cases where R1 and R2 are the same), a plant disease controlling method applying the plant disease control agent on plants suffering from diseases, and a novel compound represented by formula (1) or salt thereof.
    Type: Grant
    Filed: December 22, 2011
    Date of Patent: May 26, 2020
    Assignee: SDS BIOTECH K.K.
    Inventors: Keijitsu Tanaka, Yusuke Amaki, Motoki Tanaka, Mutsumi Miyazaki
  • Patent number: 10653715
    Abstract: The present invention relates to methods for attenuating aging, of health maintenance, and/or treating, or delaying the onset of, an age-related condition or disorder, in a subject comprising administering to the subject an effective amount of (a) one or more compounds that sustain pharmacological activation of xenobiotic metabolism or induce fermentation by gut bacteria to produce substances that activate xenobiotic metabolism enzymes and/or stimulate xenobiotic excretion and (b) one or more chelators. A further aspect of the invention is a composition comprising (a) and (b).
    Type: Grant
    Filed: October 18, 2017
    Date of Patent: May 19, 2020
    Assignee: Longevica Theraputics Inc.
    Inventors: Alexey Ryazanov, Alexander Chikunov, Yuriy Shymkiv
  • Patent number: 10639395
    Abstract: An article having anti-microbial effect is provided. The article includes an occlusive layer; a substrate having two opposing major surfaces, wherein one opposing major surface is a nanostructured surface; a metal oxide layer, wherein the nanostructured surface is coated with the metal oxide layer and the metal oxide layer comprises a metal oxide; and a metal layer overlaying the metal oxide layer.
    Type: Grant
    Filed: November 10, 2016
    Date of Patent: May 5, 2020
    Assignee: 3M Innovative Properties Company
    Inventors: Ta-Hua Yu, Döne Demirgöz, Junkang J. Liu, Badri Veeraraghavan, Narina Y. Stepanova
  • Patent number: 10617634
    Abstract: Implementations of a topical homeopathic formulation may include an active portion including a plurality of active ingredients and a base including a plurality of inactive ingredients. The plurality of active ingredients may include one of tinctures and homeopathic preparations of Apis mellifica, Arnica montana, Atropa belladonna, Bellis perennis, Bryonia alba, Cactus grandifloras, Caulophyllum thalictroides, Cimicifuga racemose, Citrullus colocynthis, Cyclamen europaeum, Gelsemium Sempervirens, Gnaphalium polycephalum, Jonesia asoca, Juniperus Sabina, Kali carbonicum, Lilium tigrinum, Rhamnus californica, Tilia europaea, Viburnum opulus, and any combination thereof.
    Type: Grant
    Filed: March 2, 2018
    Date of Patent: April 14, 2020
    Assignee: Biolyte Laboratories, LLC
    Inventor: Daniel Kaline
  • Patent number: 10596189
    Abstract: The invention relates to an emulsion containing a mixture of an aqueous phase and an oil phase, wherein the aqueous phase comprises seawater, a viscosifier, and a humectant, and wherein the oil phase comprises polyglyceryl, hectorite, propylenecarbonate, t-butyl alcohol, a polyacrylate crosspolymer-6, at least one viscosifier, at least one emulsifier, at least one co-emulsifier, and at least one emollient, such that the phases forming the emulsion are stabilized. Another object of the present invention is the method of manufacture, which allows producing the emulsion with seawater described herein in detail.
    Type: Grant
    Filed: January 29, 2018
    Date of Patent: March 24, 2020
    Assignee: BLUE SEA LABORATORIES, S.L.
    Inventors: Juan Ramón García Gómez, Jorge Díaz-Crespo Cardona
  • Patent number: 10583205
    Abstract: Systems, methods and related devices used to produce and collect polarized noble gas to inhibit, suppress, detect or filter alkali metal nanoclusters to preserve or increase a polarization level thereof. The systems can include a pre-sat chamber that has an Area Ratio between 20 and 500.
    Type: Grant
    Filed: October 15, 2019
    Date of Patent: March 10, 2020
    Assignee: Duke University
    Inventors: Matthew S. Freeman, Bastiaan Driehuys
  • Patent number: 10576112
    Abstract: This document provides bacterial compositions. For example, bacterial compositions having a combination of different bacterial strains formulated in a manner to maintain the stability of the bacteria are provided.
    Type: Grant
    Filed: January 4, 2016
    Date of Patent: March 3, 2020
    Assignee: Melaleuca, Inc.
    Inventor: Subhendu Nayak
  • Patent number: 10543230
    Abstract: Redox signaling gels are disclosed. Such gels include a composition with at least one reactive oxygen species (ROS) and a rheology modifier. Also presented herein is a process for making the gels which includes making the composition by taking the steps of purifying water to produce ultra-pure water, combining a salt to the ultra-pure water to create a salinated water, electrolyzing the salinated water at a temperature of 4.3 to 5.8° C. such that the electrolyzing is accomplished with an anode, cathode and power source such that the power source comprises a transformer and a rectifier and does not comprise a filter capacitor.
    Type: Grant
    Filed: April 20, 2017
    Date of Patent: January 28, 2020
    Assignee: RDG HOLDING, INC.
    Inventors: Andrew Hoover, James Pack
  • Patent number: 10493263
    Abstract: A system and method includes delivery of a redox gas solution to treat onychomycosis, wherein the redox gas solution comprises a reactive species dissolved in a perfluorocarbon liquid, and wherein the perfluorocarbon liquid is dispensed onto a gas-permeable membrane and the perfluorocarbon liquid comprises of an anti-inflammatory in a perfluorocarbon liquid and wherein the reactive species may include, alone or in combination, one or more of reactive oxygen, reactive nitrogen, reactive chlorine, or reactive bromine species, and the perfluorocarbon liquid may include perfluorodecalin.
    Type: Grant
    Filed: August 10, 2017
    Date of Patent: December 3, 2019
    Inventors: Jeffrey N Roe, Timothy C Grammer, Eric Tridas, Raul Ignacio Barrera-Barraza, Joel Sterling Douglas
  • Patent number: 10485819
    Abstract: Disclosed herein are ionic aqueous compositions useful as nasal passage washes to aid in the resorption of edema of the respiratory mucosa, e.g., the nasal mucosa, for the treatment of respiratory tract and/or respiratory mucosal-related conditions, including, e.g., chronic rhinosinusitis, sinusitis, allergic rhinitis and nasal polyps. The composition includes an ionic aqueous solution and algae-derived constituents, such as branched, sulfated polysaccharides having an average molecular weight greater than 4 kDa and comprising L-fucose and sulfate ester groups or extracts from brown algae. Also disclosed are methods and pharmaceutical compositions for treating respiratory tract and/or respiratory mucosal-related conditions, including, e.g., chronic rhinosinusitis.
    Type: Grant
    Filed: November 28, 2014
    Date of Patent: November 26, 2019
    Assignee: Gerolymatos International S.A.
    Inventor: Konstantinos Alevizopoulos
  • Patent number: 10391266
    Abstract: Embodiments of the present disclosure provide systems and devices for delivering gaseous Nitrous Oxide (gNO) under therapeutic parameters to reduce infection in a subject. Certain embodiments include devices and systems for delivering pressurized gNO to reduce bioburden and promote healing in the wounds of subjects having various disease conditions, including skin and soft tissue infections (SSTIs) and osteomyelitis. In some embodiments, the present disclosure provides portable wound healing devices for delivering pressurized gNO to the site of a wound to treat various disease conditions in a subject.
    Type: Grant
    Filed: November 12, 2015
    Date of Patent: August 27, 2019
    Assignee: Hansen Pharmaceutical, LLC
    Inventors: Jeffrey L. Jensen, Christopher C. Miller, Daniel Packert, Gerhild Packert
  • Patent number: 10245236
    Abstract: A treatment product for a mouth-related disorder, and associated method of treatment, where the treatment product includes an initially sealed dispensing package and a composition disposed in said package, the composition including one or more vitamins, one or more amino acids, and Xylitol (a natural composition), where the composition is a liquid at room temperature and solid or substantially solid when administered to a subject's mouth.
    Type: Grant
    Filed: January 12, 2018
    Date of Patent: April 2, 2019
    Inventor: Lisa Carroll
  • Patent number: 10221152
    Abstract: The present invention relates to a use of mycophenolate mofetil or a pharmaceutically acceptable salt thereof in the manufacture of a medicament against influenza virus. The present invention also relates to a use of mycophenolate mofetil or a pharmaceutically acceptable salt thereof in the manufacture of a medicament against drug-resistant influenza virus strains. The present invention is further related to a method for treating influenza in a subject, comprising administering to said subject an effective amount of mycophenolate mofetil or a pharmaceutically acceptable salt thereof.
    Type: Grant
    Filed: March 22, 2013
    Date of Patent: March 5, 2019
    Assignee: GIANT FORCE TECHNOLOGY CORPORATION
    Inventors: An-Rong Lee, Chi-Hong Chu, Wen-Liang Chang, Chen-Wen Yao, Wen-Hsin Huang, Li-Heng Pao
  • Patent number: 10184025
    Abstract: The present disclosure is directed to methods of preparing stable suspensions of precious metal nanoparticles and methods for attaching bio-molecules to the nanoparticles. The formation of nanoparticles can be accomplished by either chemical synthesis or pulsed laser ablation in a liquid. The present disclosure reveals the importance of controlling the conductivity of the dispersion medium during pulsed laser ablation in a liquid to control the particle size of the nanoparticles. The present disclosure also reveals the importance of adjusting and maintaining the conductivity in a range of 25 ?S/cm or less during storage of the nanoparticles and just prior to performing bioconjugation reactions. The control of conductivity is an important process for maintaining the nanoparticles as a stable non-aggregated colloidal suspension in a dispersion medium.
    Type: Grant
    Filed: January 23, 2014
    Date of Patent: January 22, 2019
    Assignee: IMRA America, Inc.
    Inventors: Yuki Ichikawa, Andrius Marcinkevicus, Masayuki Ito, Wei Qian
  • Patent number: 10155093
    Abstract: A gas enriched foam generating apparatus for performing medical procedures includes a foam generating tip assembly composed of a multi-channel arrangement at a proximal first end thereof and a tip at a distal second end thereof. The apparatus also includes a compressed gas unit fluidly connected to the multi-channel arrangement at a proximal first end of the foam generating tip assembly and a medical solution fluidly connected to the multi-channel arrangement at a proximal first end of the foam generating tip assembly. Compressed gas, from the compressed gas unit, and the medical solution are combined within the foam generating tip assembly in a manner generating a gas enriched foam that is ultimately dispensed from the foam generating apparatus.
    Type: Grant
    Filed: February 25, 2016
    Date of Patent: December 18, 2018
    Inventors: Frank Levy, Kimberley Levy
  • Patent number: 10098930
    Abstract: A chemically modified human Growth Hormone (rhGH) prepared by attaching a transient linker which comprises a polyethylene glycol. The chemically modified protein may have a much longer lasting rhGH activity than that of the unmodified rhGH, enabling reduced dose and scheduling opportunities and the modified rhGH may not cause lipoatrophy. Also includes methods of use for the treatment and/or prevention of diseases or disorders in which use of growth hormone is beneficial.
    Type: Grant
    Filed: January 19, 2016
    Date of Patent: October 16, 2018
    Assignee: Ascendis Pharma Endocrinology Division A/S
    Inventors: Harald Rau, Susanne Kindermann, Torben Lebmann, Grethe Norskov Rasmussen, Ulrich Hersel, Thomas Wegge, Kennett Sprogoe
  • Patent number: 10030039
    Abstract: [Object] An anticancer agent capable of continuously killing cancer cells in a plurality of phases is provided. [Solution] An anticancer agent contains a complex produced by making a metal-salen complex compound, which includes a central metal and (N, N, O, O) as a quadridentate ligand and is magnetic, bind to taxane molecules which are anticancerous; and the anticancer agent is to kill cancer cells regarding which phase transition of its cell cycle occurs between phases including Gap1, Synthesis, Gap2, and Mitosis and Cytokinesis. The present disclosure is suited for use to kill cancer cells of breast cancer and, particularly, cancer cells of triple-negative breast cancer. The present disclosure is designed to make the anticancer agent contact the cancer cells in two or more continuous phases selected from a group consisting of Gap1, Synthesis, Gap2, and Mitosis and Cytokinesis and kill the cancer cells.
    Type: Grant
    Filed: March 24, 2017
    Date of Patent: July 24, 2018
    Assignees: IHI Corporation
    Inventors: Yoshihiro Ishikawa, Haruki Eguchi
  • Patent number: 10016504
    Abstract: The invention provides a colon cleansing solution comprising: a) 300 to 800 mmol per liter ascorbate anion provided by a mixture of: (i) ascorbic acid and (ii) one or more salts of ascorbic acid the components (i) and (ii) being present in a molar ratio of from 1:4.5 to 1:7.0; and b) 10 to 200 g per liter polyethylene glycol. The invention also provides methods and kits associated with, or making use of the solutions, and compositions for the preparation of the solutions.
    Type: Grant
    Filed: March 9, 2017
    Date of Patent: July 10, 2018
    Assignee: NORGINE BV
    Inventors: Lucy Clayton, Alasdair Cockett, Mark Christodoulou, Ian Davidson, Lynn Farrag, Marc Halphen, Leighton Jones, Vanik Petrossian, Peter Stein, David Tisi, Alex Ungar, Jeffrey Worthington
  • Patent number: 9980489
    Abstract: The present invention relates to dissolved silicate compositions in which the dissolved silicate is stabilized by at least two selected osmolytes and is therefore bioavailable. The composition and its dilutions are stable over a long period of time and are used in a wide field of applications for the benefit of living organisms such as plants, animals and humans.
    Type: Grant
    Filed: March 24, 2011
    Date of Patent: May 29, 2018
    Assignee: Taminco BVBA
    Inventors: Peter Roose, Marc Demuynck, Johan De Saegher, Jean-Michel Rabasse
  • Patent number: 9925218
    Abstract: Embodiments of the invention relate to a composition, method and kit for producing galvanic cells upon application of the composition to the skin. In some embodiments, the composition comprises encapsulated half-galvanic cell units (e.g. individual and/or autonomous half-galvanic cell units) having the same ox/red potential (E°), wherein each half-galvanic cell unit comprises metal particles in the range of nano- to micro size or a mixture thereof, suspended within an aqueous solution of soluble electrolytic salt of same metal and wherein each half-galvanic cell unit is encapsulated by internal layer(s) made of hydrophilic metal (including silicon) oxide nanoparticles and external layer(s) made of hydrophobic metal (including silicon) oxide nanoparticles. The composition is useful for preventing and/or treating alopecia or for enhancing hair growth.
    Type: Grant
    Filed: July 17, 2014
    Date of Patent: March 27, 2018
    Assignee: PILOGICS L.P.
    Inventors: Dov Ingman, Erez Manor
  • Patent number: 9918476
    Abstract: A method for manufacturing a parasiticidal composition comprising at least 40% of alkali metal bicarbonate and at least 1% of silica, wherein: at least 35% of the alkali metal bicarbonate of the composition is milled in the presence of silica in order to form a mixture of particles, and if necessary, the remainder of the alkali metal bicarbonate is added to the mixture of particles to form the parasiticidal composition, and wherein said parasiticidal composition has a particle size distribution such that at least 50% by weight of the particles have a diameter of less than 100 ?m. A parasiticidal composition obtained by the present method and the use of the parasiticidal composition obtained by the present method in the form of a powder, a suspension or a gel.
    Type: Grant
    Filed: December 19, 2012
    Date of Patent: March 20, 2018
    Assignee: Solvay SA
    Inventor: Jean-Philippe Pascal
  • Patent number: 9889237
    Abstract: A medical device has a surface intended for contact with living tissue, wherein the surface comprises nanoparticles comprising a non-toxic post-transition metal such as gallium and/or bismuth, said nanoparticles having an average particle size of 500 nm or less. The nanoparticles may provide an antimicrobial effect, and thus the risk for infection may be reduced.
    Type: Grant
    Filed: May 2, 2013
    Date of Patent: February 13, 2018
    Assignee: DENTSPLY SIRONA Inc.
    Inventors: Anna Arvidsson, Ingela Mattisson, Elisabet Ahlberg, Johanna Löberg
  • Patent number: 9855234
    Abstract: The present invention is directed to diclofenac sublingual spray formulations. The present invention is also directed to methods for treating pain and inflammation by administering the formulations of the present invention to patients in need thereof.
    Type: Grant
    Filed: July 6, 2015
    Date of Patent: January 2, 2018
    Assignee: INSYS DEVELOPMENT COMPANY, INC.
    Inventors: Kiran Kumar Vangara, Daniela Bockenstedt, Ningxin Yan, Rajesh Pandya, Venkat R. Goskonda
  • Patent number: 9833471
    Abstract: A sanitizing formulation is disclosed for use as a hand sanitizer. The formulation may include hypochlorous acid, a silicone polymer or blend thereof, sodium phosphate, hydrochloric acid, and sodium magnesium silicate. Methods of using and making the sanitizing formulation are also disclosed.
    Type: Grant
    Filed: February 1, 2017
    Date of Patent: December 5, 2017
    Assignee: Reoxcyn Discoveries Group, Inc.
    Inventors: Kurt Richards, Andrew Hoover
  • Patent number: 9808555
    Abstract: Bone tissue biomimetic materials, biomimetic constructs that can be formed with the materials, and methods for forming the materials and constructs are described. The bone tissue biomimetic materials include electrospun nanofibers formed of polymers that are conjugated with peptides that include acidic amino acid residues. The materials can incorporate high levels of mineralization so as to provide mechanical strength and promote osteogenesis and/or osteoconductivity on/in the bone tissue biomimetic materials. The materials and constructs can be utilized in forming tissue engineered structures for in vitro and in vivo use. Macroscopic bone tissue biomimetic scaffolds formed from the materials can be seeded with osteogenic cells and utilized to develop bone graft materials that can exhibit strength and osteoconductivity similar to the native bone and that exhibit uniform distribution of nutrients in the scaffolds.
    Type: Grant
    Filed: March 9, 2016
    Date of Patent: November 7, 2017
    Assignee: University of South Carolina
    Inventor: Esmaiel Jabbari
  • Patent number: 9757346
    Abstract: The invention provides methods of treatment that induce satiety in a subject for a period of at least around twenty-four hours by once-daily administration to the subject of a controlled release dosage form, wherein the dosage form is administered while the subject is in the fasted state and at a time of around six to around nine hours prior to the subject's next intended meal, and wherein the dosage form comprises a controlled release composition, which comprises an enterically-coated, ileum hormone-stimulating amount of a nutritional substance and releases the majority of the nutritional substance in vivo upon reaching the subject's ileum. The invention also provides a diagnostic tool for probing the health and disease state of the ileal hormones, excess or deficiencies. The invention provides a safe vehicle for targeted deliveries of chemical, pharmaceuticals, natural substances and nutrition to the ileum.
    Type: Grant
    Filed: March 2, 2011
    Date of Patent: September 12, 2017
    Assignee: VOLANT HOLDINGS GMBH
    Inventor: Joseph M. Fayad
  • Patent number: 9757397
    Abstract: Provided according to some embodiments of the invention are methods of manufacturing a pharmaceutical composition. In some embodiments, such methods include homogenizing at a first excipient composition that includes a viscosity agent and at least one solvent to form a first premix composition; separately homogenizing at least one active pharmaceutical ingredient (API) and a second excipient composition to form a second premix composition; and combining the first premix composition and the second premix composition to form the composition. The pre-mixing of constituents may increase the stability of the API and provide uniformity of the dispersion of the constituents throughout the final topical composition.
    Type: Grant
    Filed: December 19, 2013
    Date of Patent: September 12, 2017
    Assignee: Novan, Inc.
    Inventors: Eleftherios Kougoulos, Nathan Stasko
  • Patent number: 9732464
    Abstract: A method for producing water repellent down includes soaking cleaned down in an aqueous solution having a pH ranging from 4 to 7; adding to the solution a cross-linking agent composed of a material having an isocyanate or acrylic acid functional group to provide a solution having a weight ratio of the down and the cross-linking agent ranging between 1:0.005 and 1:0.06; adding to the solution a water-drawing agent composed of a material having a siloxane functional group to provide a solution having a weight ratio of the down and the water-drawing agent ranging between 1:0.01 and 1:0.1; stirring the solution for at least 15 minutes to react the cross-linking agent and the water-drawing agent and form a water repellent layer on the surface of the down; separating the down from the solution; and oven drying the down with hot air having a temperature of at least 120° C.
    Type: Grant
    Filed: January 29, 2015
    Date of Patent: August 15, 2017
    Assignee: KWONG LUNG ENTERPRISE CO., LTD.
    Inventor: Chang-Cheng Chen
  • Patent number: 9723834
    Abstract: The present invention relates to a composition comprising a pyripyropene pesticide of the formula (I) or (II) as defined below and a base. The present invention relates also to methods of preparing and applying such compositions, as well as several uses thereof, and finally seeds, comprising said composition.
    Type: Grant
    Filed: September 13, 2011
    Date of Patent: August 8, 2017
    Assignee: BASF SE
    Inventors: Cedric Dieleman, Torsten Knieriem, Michael Krapp, Paul Ch. Kierkus, Wen Xu, Kara Benton
  • Patent number: 9669203
    Abstract: Methods and systems for inducing and passively detecting stable cavitation and/or inertial cavitation for targeted drug delivery across a biological membrane are disclosed. Such methods include administering vesicles having a nucleating agent and a therapeutic drug to a vascular system of a patient, and providing an active interval of ultrasonic exposure substantially throughout a targeted treatment zone. The ultrasonic exposure is produced by a source transducer at a specified fundamental frequency, amplitude, duty cycle, and duration. The methods also include detecting a scattered ultrasonic wave, where the scattered ultrasonic wave is received by a detection transducer. Detection of the scattered ultrasonic wave is indicative of stable and/or inertial cavitation. The ultrasonic exposure is provided intermittently in the active intervals separated by rest periods, and substantially less ultrasonic exposure is provided during the rest period than during the active interval.
    Type: Grant
    Filed: March 1, 2012
    Date of Patent: June 6, 2017
    Assignee: University of Cincinnati
    Inventors: Christy K. Holland, Kathryn E. Hitchcock, Kevin Haworth, Nikolas Ivancevich, T. Douglas Mast
  • Patent number: 9663691
    Abstract: Methods and systems are provided for producing ionized alkaline solutions (e.g. ionized alkaline water) that exhibit long-term stability when stored at room temperature.
    Type: Grant
    Filed: February 20, 2015
    Date of Patent: May 30, 2017
    Assignee: Electrolyzed Innovations, LLC
    Inventor: Philip Adams
  • Patent number: 9545429
    Abstract: Homeopathic compositions. Implementations of topical homeopathic compositions may include an actives portion including a plurality of active ingredients and a base including a plurality of inactive ingredients where the plurality of active ingredients include tinctures and/or homeopathic preparations of Actaea spicata, Aesculus hippocastanum, Arnica montana, Atropa belladonna, Bellis perennis, Bryonia alba, Calendula officinalis, Causticum, Cimicifuga racemosa, Hypericum perforatum, Kali Carbonicum, Ledum palustre, Lithium Carbonicum, Rhododendron chrysanthum, Rhus toxicodendron, Ruta graveolens, Salicylicum Acidum, and Stellaria media and one or more tinctures and/or homeopathic preparations selected from the group consisting of Althaea officinalis, Caulophyllum thalictroides, Guaiacum, Rhamnus californica, or any combination thereof.
    Type: Grant
    Filed: September 3, 2011
    Date of Patent: January 17, 2017
    Assignee: BIOLYTE LABORATORIES, LLC
    Inventor: Daniel J. Kaline
  • Patent number: 9468779
    Abstract: The invention relates to a polysaccharide gel of natural origin for dermatological use that comprises an aqueous solution of the polysaccharide of 0.1 to 5% by weight/volume, for example hyaluronic acid, and a viscous and strongly hydrophilic biocompatible alcohol at 0.5-5% by weight/volume, for example glycerol, and optionally the adjuvants that are commonly used in dermatology. The gel is prepared by mixing the polysaccharide solution and the strongly hydrophilic viscous alcohol before sterilizing the entire mixture by, for example, moist heat.
    Type: Grant
    Filed: February 14, 2014
    Date of Patent: October 18, 2016
    Assignee: ANTEIS SA
    Inventor: Gilles Bos
  • Patent number: 9446079
    Abstract: A composition of medical grade honey and silver nitrate is described for treatment of burns, ulcers, and open wounds. The disclosed composition is a gel of medical grade honey and silver nitrate in a ratio of about 211 to 1, with a moisture level of no greater than 20 percent and wherein the medical grade honey contains about 300 kg/mg of methylglyoxal. Also described are methods of making and using the honey and silver nitrate mixture for treatment of burns, ulcers and wounds including direct application to a treatment area as well as impregnating a gauze fabric with a composition of medical grade honey and silver nitrate for application to a treatment area.
    Type: Grant
    Filed: August 12, 2015
    Date of Patent: September 20, 2016
    Assignee: Links Medical Products, Incorporated
    Inventors: Thomas L. Buckley, Andrew Thain
  • Patent number: 9427411
    Abstract: The present invention relates to an antimicrobial topical composition and process for making such composition. The composition comprises of ionic silver, silver nanoparticles, and oxygen, combined within a gel medium and applied topically. The composition optimizes the ionic silver and silver nanoparticle ratio providing for sufficient ionic silver to be delivered as an immediate antimicrobial agent, and sufficient nanoparticle silver to provide time release for conversion to silver ions for continuing antimicrobial effectiveness.
    Type: Grant
    Filed: August 12, 2014
    Date of Patent: August 30, 2016
    Inventor: JoAnna M. Esty
  • Patent number: 9421226
    Abstract: The present invention provides methods for maintaining electrolyte balance and hydration in a person habituated to strenuous physical exertion by assaying perspiration generated by the person under conditions of strenuous physical exertion to determine the volume of perspiration as a function of duration of exertion and the sodium content of the person's perspiration during strenuous physical exertion The person is assigned to one of a plurality of groups of individuals, each group differing in the amount of sodium present in the perspiration and having a unique rehydration solution. The invention also provides for a set rehydration compositions, each member of the set comprising sodium and chloride differing from the weight percentage of sodium in the other members of the set and each member of the set being perceptually labeled to distinguish that member from the other members of the set by one of the human senses.
    Type: Grant
    Filed: July 18, 2013
    Date of Patent: August 23, 2016
    Assignee: Heat Sport Sciences, Inc.
    Inventors: Arthur R. Bartolozzi, Sandra Fowkes Godek
  • Patent number: 9333224
    Abstract: The present invention relates to compositions comprising a silicate and methods of use thereof. In particular, the compositions of the present invention are suitable for treating inflammatory conditions, cancer, bacterial and viral infections, and infected and uninfected wounds. The compositions of the present invention can also be useful in treating spinal cord injury, tissue remodeling, and promoting bone growth and repair.
    Type: Grant
    Filed: February 4, 2013
    Date of Patent: May 10, 2016
    Assignee: HS PHARMACEUTICALS, LLC
    Inventors: Richard Thomas Stanley, Sr., David Edward Stanley, Marcus Blackstone, Thomas Wagner
  • Patent number: 9332760
    Abstract: A substrate contains a composition including VOSO4, K11H[(VO)3(SbW9O33)2], Na9[SbW9O33], oxacillin and 5-chloro-2-(2,4-dichlorophenoxy)phenol.
    Type: Grant
    Filed: January 24, 2013
    Date of Patent: May 10, 2016
    Assignee: VB JAPAN TECHNOLOGY CO., LTD.
    Inventors: Katsuaki Dan, Toshihiro Yamase, Hiromichi Ichikawa
  • Patent number: 9314549
    Abstract: Bone tissue biomimetic materials, biomimetic constructs that can be formed with the materials, and methods for forming the materials and constructs are described. The bone tissue biomimetic materials include electrospun nanofibers formed of polymers that are conjugated with peptides that include acidic amino acid residues. The materials can incorporate high levels of mineralization so as to provide mechanical strength and promote osteogenesis and/or osteoconductivity on/in the bone tissue biomimetic materials. The materials and constructs can be utilized in forming tissue engineered structures for in vitro and in vivo use. Macroscopic bone tissue biomimetic scaffolds formed from the materials can be seeded with osteogenic cells and utilized to develop bone graft materials that can exhibit strength and osteoconductivity similar to the native bone and that exhibit uniform distribution of nutrients in the scaffolds.
    Type: Grant
    Filed: April 24, 2014
    Date of Patent: April 19, 2016
    Assignee: University of South Carolina
    Inventor: Esmaiel Jabbari
  • Patent number: 9295254
    Abstract: A method of treating soils to eradicate or reduce the proliferation of nematodes said method comprising the application of select metal ion-acid compositions to the soil.
    Type: Grant
    Filed: December 10, 2012
    Date of Patent: March 29, 2016
    Assignee: SCIESSENT LLC
    Inventor: Naseem Khan
  • Patent number: 9232804
    Abstract: The present invention includes a composition for sterilizing a bioscaffold, comprising slightly acidic electrolyzed water (SAEW) as an active ingredient, and a method for sterilizing a bioscaffold using the same. The slightly acidic electrolyzed water according to the present invention has excellent effects on the sterilization of bioscaffolds and the removal of immunogenic antigens and a little effect on extracellular matrix, such as glycosaminoglycans or collagen. Moreover, the scaffold sterilized with the slightly acidic electrolyzed water has excellent cell attachment and has no toxicity, and thus the slightly acidic electrolyzed water can be effectively used for the sterilization of bioscaffolds.
    Type: Grant
    Filed: October 2, 2013
    Date of Patent: January 12, 2016
    Assignee: KNU University-Industry Cooperation Foundation
    Inventors: Heung Myong Woo, Kyung Mee Park, Kamal El Din Hany Hussein
  • Patent number: 9173899
    Abstract: Method of treating autistic spectrum disorder includes administration to a person of a product, which contains stable water clusters, such as stable double helix water clusters, by taking the products by mouth, applying the products on a skin of the person, intaking the product by breathing, introducing the products intravenously, etc.
    Type: Grant
    Filed: January 31, 2013
    Date of Patent: November 3, 2015
    Assignee: D & Y Laboratories Inc.
    Inventors: Shui Yin Lo, David L. Gann
  • Patent number: 9132100
    Abstract: The present invention is directed to a patch containing a non-steroidal anti-inflammatory drug including an adhesive layer composed of a transdermal preparation on a support, the transdermal preparation including a) 10 to 40% by weight of a nonaqueous base material based on the total weight of the transdermal preparation, b) 1 to 10% by weight of a non-steroidal anti-inflammatory drug based on the total weight of the transdermal preparation, and c) a polyethylene glycol component composed of 0.3 to 5% by weight of a low molecular weight polyethylene glycol based on the total weight of the transdermal preparation, and 1 to 10% by weight of a high molecular weight polyethylene glycol based on the total weight of the transdermal preparation.
    Type: Grant
    Filed: December 4, 2012
    Date of Patent: September 15, 2015
    Assignee: Reckitt Benckiser Healthcare International Limited
    Inventors: Naoki Murai, Seijiro Yama
  • Patent number: 9119395
    Abstract: The invention relates to novel biocidal active substance mixtures containing o-phenylphenol and amines, methods for the production thereof, the use thereof for protecting technical materials and products from being infested and destroyed by microorganisms, and microbicidal agents based on said novel mixtures.
    Type: Grant
    Filed: October 6, 2006
    Date of Patent: September 1, 2015
    Assignee: LANXESS Deutschland GmbH
    Inventors: Peter Wachtler, Martin Kugler