Abstract: The present invention provides a pharmaceutical composition for the oral administration of an H.sub.2 -antagonist. The composition includes an H.sub.2 -antagonist and a silicate taste-masking agent capable of forming an adsorbate complex with the H.sub.2 -antagonist wherein the complex exhibits a non-bitter taste. The complex inhibits the release of the H.sub.2 -antagonist in the oral cavity.

Abstract: A composition for the treatment of premenstrual syndrome comprising an effective amount of calcium, magnesium, an analgesic and a diuretic sufficient to reduce the symptoms of premenstrual syndrome.

Abstract: An ophthalmologic composition therapeutic in the treatment of dry eye syndrome is disclosed. The composition is comprised of a minimally soluble salt of calcium that has been finely divided into particles having a mean diameter of 10 to 60 microns. The calcium salt particles are suspended within a pharmacologically acceptable carrier such as petrolatum or physiological saline. The composition is delivered to the ocular surface in an amount and for a time sufficient to alleviate the symptoms of dry eye.

Abstract: A method of installing in a building a suspension containing paramagnetic susceptible elements consisting essentially of:(A) providing in a non-metallic container 5-12 pounds of a composition consisting essentially of (i) 30-99 wt % of a carbonate or a mixture of two or more carbonates selected from the group consisting of magnesium carbonate, calcium carbonate, strontium carbonate, barium carbonate and mixtures thereof, wherein the carbonate or mixture of carbonates are in powder form, (ii) 1-70 wt % of activated carbon in powder form, (iii) 0.

Abstract: The present invention provides a fungicide composition which contains ingredients which are biocompatible for purposes of agricultural applications, and which are harmless to animals and humans. An invention fungicide composition in the form of a dry blend formulation remains non-caking and free-flowing under storage conditions. Illustrative of an invention fungicide composition is a formulation which has a content of sodium bicarbonate, potassium bicarbonate, xanthan gum, dialkylsulfosuccinate salt and alkyl sulfate salt surfactants, and magnesium silicate anti-caking ingredient. The xanthan gum and surfactants function as an effective spreader-sticker and film-forming medium when the composition is diluted with water for agricultural applications.

Abstract: A kit containing benzeneacetonitrile and calcium or dihydropyridine and calcium hypertensive mammals may be treated to lower mean blood pressure by administering a calcium channel blocking agent together with one or both of a calcium supplement and Vitamin D. The hypotensive effect of this combination is synergistic and the dose response is more predictable than the administration of any of these agents singly.

Abstract: The present invention relates to an aqueous pharmaceutical suspension for oral use, and a method of preparation, having antacid and antiulcer properties which contains a therapeutically effective amount of calcium carbonate in combination with magnesium carbonate and/or magnesium trisilicate and a carboxylic acid pH adjusting agent.

Abstract: A composition comprising sucralfate and one or more anti-acid epigastralgic relieving agents in a weight ratio of between 0.5:1.0 to 1.3 sucralfate to anti-acid epigastralgic relieving agent and a method of using the composition for relieving symptoms of gastrointestinal mucosal irritation in mammals. The composition may be either in liquid or solid dose form having a combined composition weight percentage of 10-30% per 5 milliliter volume of liquid or 40-85% per solid unit dose form.

Abstract: The present invention is directed to a method for treating symptoms associated with vascular headaches. The method comprises administering to an individual exhibiting symptoms associated with vascular headache symptomatology a therapeutically effective amount of a combination of calcium and vitamin D.

Abstract: A hazard-free method for controlling insects using a non-toxic composition that kills by dehydration. The invention includes a process for making the composition in the form of crystalline particles which penetrate directly through the exoskeleton of an insect. In operation, the particles work themselves between the insect's protective body plates and then pierce the exoskeleton. Once inside, the particles absorb up to four times their weight of the vital body fluids of the insect. The penetration of the body plates and exoskeleton and/or dehydration ultimately results in death of the insect.

Abstract: The present invention provides a fungicide composition which contains ingredients which are biocompatible for purposes of agricultural applications, and which are harmless to animals and humans. An invention fungicide composition in the form of a dry blend formulation remains non-caking and free-flowing under storage conditions. Illustrative of an invention fungicide composition is a formulation which has a content of sodium bicarbonate, potassium bicarbonate, xanthan gum, dialkylsulfosuccinate salt and alkyl sulfate salt surfactants, and magnesium silicate anti-caking ingredient. The xanthan gum and surfactants function as an effective spreader-sticker and film-forming medium when the composition is diluted with water for agricultural applications.

Abstract: A method for prolonged delivery of a therapeutic agent to the eye is disclosed. The method provides for the addition of a desired drug to a suitable, preferably non-aqueous, vehicle. An amount of the vehicle containing a therapeutic dose of the drug is placed on the extraocular skin adjacent to the lateral canthus of the eye. Movements of the orbicularis oculi associated with the scissor-like closing of the lids of the eye continuously transport small portions of the drug containing vehicle into the interpalpebral space where the drug is released to the cornea for intraocular penetration and treatment effected. The method of the invention is particularly effective in delivering insoluble calcium salts for the treatment of dry eye.

Abstract: Hypertensive mammals may be treated to lower mean blood pressure by administering a calcium channel blocking agent together with one or both of a calcium supplement and Vitamin D. The hypotensive effect of this combination is synergistic and the dose response is more predictable than the administration of any of these agents singly.

Abstract: This invention provides a novel pesticide composition having a bicarbonate-containing inorganic salt ingredient which exhibits fungicidal activity, and which enhances the efficacy of a C.sub.8 -C.sub.22 fatty acid insecticidal ingredient for the treatment of agricultural and horticultural plants. An invention pesticide composition also can contain a water-soluble organic compound which functions as a compatibility enhancing agent for the active ingredients, and improves the spreadability and adhesiveness of the composition ingredients when applied to foliage as an aqueous pesticide formulation.

Abstract: Method for alleviating symptoms of nicotine withdrawal employing calcium carbonate.

Abstract: The invention relates to a process for the preparation of a tablet or dragee composition containing a moisture-, heat- and light-sensitive compounds having monoclinic crystalline structure as active ingredients, which comprises homogenizing the active ingredient with 0.2 to 1.5 parts by weight of an anhydrous alkaline earth metal salt and 0.5 to 2.5 parts by weight of microcrystalline cellulose calculated for the active ingredient and optionally with one or more pharmaceutically acceptable carrier(s) and/or additive(s) and compressing the homogeneous mixture obtained to tablets in a manner known per se and, if desired, coating the tablet thus obtained in a manner known per se.

Abstract: A therapeutic composition for treating the manifestations of overindulgence in alcohol includes effective amounts of acetaminophen, one or more antacids agents and caffeine, all provided in finely powdered form suspended in a medium including glycerin, xanthan gum and purified water, along with a dissolved simple sugar, such that the composition is basic and has a pH less than 9. The use of a flavorant, a colorant, a stomachic and preservatives in the composition is disclosed. A method of oral administration of the composition is also disclosed.

Abstract: An ophthalmologic composition therapeutic in the treatment of dry eye syndrome is disclosed. The composition is comprised of a minimally soluble salt of calcium that has been finely divided into particles having a mean diameter of 10 to 60 microns. The calcium salt particles are suspended within a pharmacologically acceptable carrier such as petrolatum or physiological saline. The composition is delivered to the ocular surface in an amount and for a time sufficient to alleviate the symptoms of dry eye.

Abstract: This invention relates to a pharmaceutical composition for use in the treatment of pain and inflammation and the treatment of acid indigestion, sour stomach, heartburn and symptoms of upset stomach associated with these conditions in a mammalian organism, said composition comprising:(i) an analgesically and anti-inflammatory effective amount of (S)-ibuprofen, or a salt thereof, substantially free of (R)-ibuprofen;(ii) an amount effective in the treatment of acid indigestion, sour stomach and/or heartburn of at least one of the antacids; and(iii) optionally, an amount effective in treating excess gas and flatulence of an anti-gas agent.

Abstract: A pharmaceutical composition useful for treating gastroesophageal reflux comprising oxethazaine and a carrier selected from alginic acid and alginates.

Abstract: Pharmaceutical medications and methods are disclosed for providing instant and sustained relief from pain or symptoms associated with episodic heartburn in humans. The medications consist essentially of antacids and histamine H.sub.2 -receptor antagonists, and may be administered on an as-needed basis in liquid or solid dosage forms. Typical antacids which may be used in combination with the histamine H.sub.2 -receptor antagonist are conventional antacids which are well known and widely used in the treatment of excess acid related gastrointestinal dysfunctions. Exemplary of typical antacids include, sodium bicarbonate, calcium carbonate, magnesium hydroxide and aluminum hydroxide, as well as commercially available high potency, flavored antacids. Histamine H.sub.2 -receptor antagonists which may be used in combination include those conventionally used in the treatment of peptic ulcers, such as, for example, cimetidine, ranitidine, famotidine and nizatidine.

Abstract: A composition for foaming preparation comprising (a) an organic acid of which the crystal surface is coated with a sugar and (b) a carbonate is disclosed. In the composition, an organic acid is completely shut off from a carbonate by a sugar coating so that the acid does not react with the carbonate over a prolonged storage time. When the composition is put into mouth, the sugar which covers the acid is readily dissolved, allowing the acid and the carbonate to react and to generate carbon oxide gas. An excellent foaming calcium preparation can be produced by using calcium carbonate as the carbonate or by adding other salt of calcium to the composition. Such a calcium preparation gives a good taste and favorable feeling upon administration. It is especially suitable for regular administration of calcium over an extended period of time.

Abstract: A pharmaceutical composition is provided for the protection of the oesogastroduodenal mucous membrane, which composition has an active antacid component comprising sufficient guar gum to provide antacid and buffering effect at a pH of from 0.8 to 3.5, and at least one antacid agent other than guar gum in an amount effective as an antacid.

Abstract: A method of reducing cracking and peeling of human fingernails and toenails and, apparently, of polishing and hardening and toughening them. A finely divided powder comprising substantially pure dolomite is provided. The powder is manually rubbed on the fingernails for periods on a regular schedule. After a short time, fingernails that had previously been subject to chipping and cracking are found to resist chipping and cracking and to appear to have a harder and tougher surface.

Abstract: A composite which is obtainable by mixing calcium pantothenate with a per se neutral or basic magnesium or calcium lactate or carbonate in the presence of water and/or a lower alcohol, and drying the resulting mixture, is stable with little decrease of the content of calcium pantothenate during storage.When other drugs, which may cause changes as the result of combination with calcium pantothenate, are combined to produce various preparations, the composite is stable because they are hardly affected by other ingredients and hardly affect other ingredients; for example, in production of tablets, powders, granules, and capsules, complicated processes to separate from other ingredients are not required, and the excessive amount in anticipation of the loss along with time can be reduced markedly.

Abstract: Eggshells are utilized after preliminary treatment for medical purposes for treating certain diseases and to compensate for deficiencies of mineral in living tissues, particularly in bone tissues in a form which is acceptable by the body.

Abstract: A mouth cleansing composition for removing dried secretion deposits in and around a user's oral cavity is disclosed. The composition is a mixture of an aqueous salt containing solution, glycerin, hydrogen peroxide, and an acid neutralizing agent.

Abstract: A concentrated suspension of calcium carbonate particles in a liquid carrier that is compatible with a capsule shell material. The suspension is pourable and pumpable and may be used to provide antacid capsules.

Abstract: A method of increasing the bone density of post-menopausal women employs a calendar-oriented regimen of estrogen, progesterone and calcium. Such a regimen may be dispensed from a calendar-oriented pill dispenser having numerical indicia identifying each pill-containing enclosure with a given calendar date.

Abstract: Orally ingestible liquid compositions for suspending therein orally administrable pharmaceutically active compositions comprising triglycerides, propylene glycol ester, or monoacetylated glycerides of medium chain length alkanoic acids, polyglycerol esters, and colloidal silicon dioxide.

Abstract: A method for the treatment of premenstrual syndrome (PMS) by administering a therapeutically effective dose of calcium to an individual manifesting symptoms of PSM. Calcium may be administered in any appropriate form and manner. In a randomized, double-blind crossover placebo-controlled study of 33 women PMS symptomology was reduced on calcium treatment during both the luteal and the menstrual phases.

Abstract: A means for promoting the neutralization reaction between particulate calcium carbonate and ionized phosphate by adding a material formed by the reaction of particulate calcium carbonate and dilute hydrofluoric acid. The products of this invention are useful in lowering serum phosphate levels in patients undergoing renal dialysis, and are also useful as antacids. These products are also useful in the treatment of water and waste water to lower phosphate content.

Abstract: An orally administrable composition and method for reducing serum cholesterol levels are disclosed. A pharmaceutical composition comprising guar gum, and a dispersing mineral salt such as, for example, calcium carbonate, magnesium carbonate, or potassium carbonate, is administered to humans to reduce serum cholesterol levels.

Abstract: A solid stable sugar free and sodium free calcium pharmaceutical composition is disclosed comprising a calcium organic salt, calcium carbonate and an organic polycarboxylic acid.

Abstract: A pharmaceutical composition suitable for oral adminstration comprising particulate cimetidine suspended in an aqueous phase containing a buffer which maintains the pH at greater than 7 and a suspending agent.

Abstract: A slow release tablet or the like for releasing fluoride and calcium ions in a manner so as to reduce the formation of calcium fluoride and to reduce gastrointestinal discomfort comprising the use of MFP together with a calcium-containing composition.

Abstract: Combinations of gamma-linolenic acid (GLA) and calcium, presented for administration in assimilable dosage unit form in doses of 1 mg to 100 g GLA and 1 mg to 20 g calcium daily, for example, for the treatment of osteoporosis and other bone disorders involving calcium loss from the bones, of premenstrual syndrome, or of hypertension.

Abstract: The present invention comprises a composition of matter consisting essentially of citric acid and one or more calcium compounds selected from the group consisting of calcium hydroxide, calcium carbonate and calcium oxide. The composition of matter is preferably a substantially dry mixture which may be used, for example, as a powder for making an "instant" beverage of potable liquid. A preferred calcium compound/citric acid molar ratio in the composition of matter of the present invention is between about 0.6 and about 1.5.In a most preferred embodiment, the composition of matter of the present invention consists essentially of calcium hydroxide and citric acid having a calcium compound/citric acid or calcium hydroxide/citric acid molar ratio of about 1.25.The composition of matter of the present invention has a utility demostrated by dissolution in water to form a liquid dietary calcium supplement comprising soluble calcium citrate.

Abstract: An agent for increasing the pH value of dental plaque, which contains at least one highly disperse, poorly soluble oxide, hydroxide or pure salt of one or more alkaline earth metal elements and a weak acid, having a specific surface area greater than 6 m.sup.2 /g and a concentration of lattice defects which corresponds to a half width of the X-ray peaks for Cu-K.alpha. radiation at glancing angles from 20.degree. to 23.degree. of more than 0.25 degrees, and a process for its preparation.

Abstract: Decubitus ulcers are treated with a preconditioning aqueous medium and then with a non-systemic basic ointment. The aqueous medium comprises an aqueous solution of pyridoxine hydrochloride, zinc chloride, dextrose, ethanol and sodium chloride, with a trace of phenyl mercuric nitrate N.F., and has a pH in the range of 4.3 to 6.8 so as to facilitate ionization of naturally occurring amino acids at the wound site. The ointment comprises calcium carbonate, magnesium hydroxide, aluminum hydroxide, zinc chloride, sodium chloride, anhydrous lanolin, hydrophilic ointment and vitamin A and has a pH in the range of from about 6.5 to 9.0 so as to facilitate chelation of the amino acid and zinc ions and enhance tissue repair.

Abstract: A chewable tooth cleaning composition which removes dental plaque from the chewing surfaces of the teeth has incorporated into a chewing gum formulation about 20% to about 40% by weight, based on the weight of the total composition, of a calcium carbonate abrasive having a specific particle size distribution.