Containing Or Obtained From Panax Or Acanthopanax (e.g., Ginseng, Etc.) Patents (Class 424/728)
  • Patent number: 10688144
    Abstract: Provided are a pharmaceutical composition for preventing and/or treating osteoarthritis comprising an extract of Angelica gigas Nakai, a pharmaceutical composition for preventing and/or treating osteoarthritis comprising a mixed extract of Angelica gigas Nakai and Cnidium officinale, and a method of preventing and/or treating osteoarthritis comprising administering the extract of Angelica gigas Nakai or the mixed extract of Angelica gigas Nakai and Cnidium officinale.
    Type: Grant
    Filed: February 1, 2017
    Date of Patent: June 23, 2020
    Inventor: Kang Hyun Lee
  • Patent number: 10588927
    Abstract: The present invention relates to a composition comprising the mixed extract of mulberry and Poria cocos peel for preventing, improving or treating neurodegenerative disorders. The mixed extract of mulberry and Poria cocos peel which is the active ingredients contained in the composition of the present invention, has a memory improving activity through inhibiting of acetylcholine esterase and a neuroprotective effects and neuron protection by inhibiting the formation of beta amyloid and tau phosphorylation and promoting NGF production. Thus, the present invention may be useful as a pharmaceutical composition for preventing or treating degenerative neurological diseases, or as a health food for the above purpose.
    Type: Grant
    Filed: December 3, 2015
    Date of Patent: March 17, 2020
    Assignee: NeuroBo Pharmaceuticals, Inc.
    Inventors: Sang Zin Choi, Mi Won Sohn, Hyo Sang Go, Ja Young Ryu, Jin Seok Jeong, Song Hyen Choi, Eun Jin Kim, Young Woong Cho, So Young Kim
  • Patent number: 10568931
    Abstract: Provided is a treatment composition for damage treatment and regeneration promotion of corneal epithelial cells containing gintonin as an active ingredient which is glycolipoprotein or its aggregate isolated from ginseng. Since the gintonin as a drug containing high-concentration LPA has an effect of increasing the concentration of LPA in damaged cornea and inducing the proliferation of corneal epithelial cells to rapidly and significantly restore the damage of the cornea, the composition of the present disclosure can be usefully used as drugs for treatment of corneal erosion and corneal ulcer or equivalent therapeutic agents for corneal injury in humans and animals.
    Type: Grant
    Filed: March 8, 2017
    Date of Patent: February 25, 2020
    Assignee: GINTONIN KU BIOTECH CO., LTD.
    Inventors: Seung-Yeol Nah, Joon-Young Kim, Hyeon-Joong Kim, Seok-Won Jung
  • Patent number: 10488417
    Abstract: The present invention describes the use of the Chinese medicinal compounds ginsenoside RB1, dihydromyricetin and salvianohc acid B, for use in diagnosing, monitoring and treating synucleinopathies, such as Parkinson's disease, in patients.
    Type: Grant
    Filed: November 14, 2014
    Date of Patent: November 26, 2019
    Assignee: United Arab Emirates University
    Inventor: Omar M. Ali El-Agnaf
  • Patent number: 10478498
    Abstract: The invention encompasses formulations and methods for the production thereof that permit the delivery of concentrated protein solutions. The inventive methods can yield a lower viscosity liquid protein formulation or a higher concentration of therapeutic or nontherapeutic proteins in the liquid formulation, as compared to traditional protein solutions. The inventive methods can also yield a higher stability of a liquid protein formulation.
    Type: Grant
    Filed: October 21, 2016
    Date of Patent: November 19, 2019
    Assignee: REFORM BIOLOGICS, LLC
    Inventors: David S. Soane, Philip Wuthrich, Rosa Casado Portilla, Robert P. Mahoney, Mark Moody, Daniel G. Greene
  • Patent number: 10471000
    Abstract: The present disclosure provides a method for preparing an anti-wrinkle functional cosmetic substance comprising cutting herbal materials comprising Angelica gigas root, Rehmannia glutinosa root, a paeonia albiflora root, Mentha arvensis, Angelica dahurica root, Scrophularia buergeriana, Rheum undulatum root/stalk/stem, Sanguisorba officinalis root, and Cinnamomum cassia bark into pieces, putting a mixture of the herbal material pieces, talc, a pearl powder, deep ocean water into an extractor, sterilizing the mixture, then fermenting the mixture by mixed lactobacillales strain, and then hot-water extracting the mixture into a solid, freeze-drying the extracted solid into a freeze-dried powder, and dissolving and high-speed mixing the freeze-dried powder, adenosine, and borax in a beeswax, a perilla oil, an Olea europaea (olive) fruit oil, and a Helianthus annuus (sunflower) seed oil heated and Chamaecyparis obtusa water heated.
    Type: Grant
    Filed: December 6, 2016
    Date of Patent: November 12, 2019
    Inventor: Chung-Sig Lee
  • Patent number: 10434128
    Abstract: Provided is a method of treating ovotoxicity of an individual, including administering an Ulmi cortex extract to an individual in need of treatment. The present disclosure may exhibit an effect of preventing, alleviating, or treating ovarian aging or premature ovarian failure by inhibiting oxidative stress or ovotoxicity of the ovaries.
    Type: Grant
    Filed: June 28, 2018
    Date of Patent: October 8, 2019
    Assignee: Dongguk University Gyeongju Campus Industry-Academy Cooperation Foundation
    Inventors: Dong Il Kim, Ju Hee Lee, Deok Ho Kim, Jae Hyun Han, Su Hyun Kim
  • Patent number: 10391110
    Abstract: The present invention relates to a pharmaceutical composition containing ginsenoside F1 or Rh1 for preventing or treating vascular leak syndrome, to a method for treating vascular leak syndrome using the pharmaceutical composition, and to a food composition containing ginsenoside F1 or Rh1 for preventing or ameliorating vascular leak syndrome. The ginsenoside F1 or Rh1 provided in the present invention can promote angiogenesis and suppress vascular leakage, and thus can be widely utilized in the effective prevention or treatment of vascular leak syndrome.
    Type: Grant
    Filed: May 19, 2016
    Date of Patent: August 27, 2019
    Assignee: Intelligent Synthetic Biology Center
    Inventors: Ho Min Kim, Ji In Kang, Sun Chang Kim, Chang Hao Cui
  • Patent number: 10314875
    Abstract: Disclosed herein are methods for treating mammals with HIV/AIDS comprising administering a therapeutically effective amount of a composition comprising an extract of Rubia cordifolia. The extract is preferably an alcohol extract, an aqueous extract, or mixtures thereof. The alcohol preferably comprises ethanol, isopropyl alcohol, or mixtures thereof.
    Type: Grant
    Filed: December 11, 2015
    Date of Patent: June 11, 2019
    Assignee: The Florida International University Board of Trustees
    Inventors: Madhavan P. N. Nair, Zainulabedin M. Saiyed, Nimisha H. Gandhi
  • Patent number: 10314326
    Abstract: The present invention features a composition and method for suppressing appetite. The composition of the invention is composed of yerbe maté extract, guarana extract, and damiana extract in combination with a dietary fiber.
    Type: Grant
    Filed: October 6, 2017
    Date of Patent: June 11, 2019
    Assignee: NATURES REMEDIES LTD
    Inventors: Jason Christian Grovenor Halford, Trevor Rodney Jarman
  • Patent number: 10201577
    Abstract: A nutritional supplement composition and associated method enhances working and long term memory support in a healthy adult person, and includes a Panax Ginseng extract and Ginkgo Biloba extract in a ratio a:b, wherein a for the Panax Ginseng extract is between about 1.9 and 2.8 and b for the Ginkgo Biloba extract is between bout 0.8 and 1.1. It is formulated for oral administration such that the Panax Ginseng extract and Ginkgo Biloba extract together account for at least 90 wt % of a dosage unit of the nutritional supplement composition. The Panax Ginseng extract and Ginkgo Biloba extract together may be present in the amount from about 320 mg to 960 mg. The dosage unit of the composition may be equal to or less than about 1,000 mg.
    Type: Grant
    Filed: February 14, 2017
    Date of Patent: February 12, 2019
    Assignee: KEYVIEW LABS, INC.
    Inventor: Scott Eibel
  • Patent number: 10188688
    Abstract: There is disclosed the use of a composition for promoting neuronal growth of neurons in tissues of the central or peripheral nervous system. There is also disclosed a method for inducing proliferation or differentiation of neuronal cells.
    Type: Grant
    Filed: February 8, 2016
    Date of Patent: January 29, 2019
    Assignee: MOLEAC PTE. LTD.
    Inventors: Michel Maurice Jacques Lazdunski, Catherine Louise Heurteaux, David Picard
  • Patent number: 10172900
    Abstract: The present invention relates to a ginseng mixed composition with improved bioavailability of saponin. Further, the present invention relates to a method for improving saponin bioavailability of a subject comprising: administering to the subject an effective amount of at least one extract selected from a Schizandra chinensis extract and a Liriope platyphylla extract that improves saponin bioavailability in the subject.
    Type: Grant
    Filed: May 25, 2010
    Date of Patent: January 8, 2019
    Assignee: AMOREPACIFIC CORPORATION
    Inventors: Hee Young Jeon, Ji Hae Lee, Kyung Mi Joo, Chan Woong Park, Kyung Min Lim, Dae Bang Seo, Sang Jun Lee
  • Patent number: 10124017
    Abstract: The present invention discloses a new use of ginsenoside M1 for treating or preventing gout.
    Type: Grant
    Filed: March 17, 2016
    Date of Patent: November 13, 2018
    Inventors: Sheau-Long Lee, Yu-Chieh Lee, Kuo-Feng Hua
  • Patent number: 10072022
    Abstract: Certain embodiments are directed to oridonin analogs or derivatives. In certain aspects, the derivatives are used as anticancer or anti-inflammatory agents.
    Type: Grant
    Filed: June 28, 2017
    Date of Patent: September 11, 2018
    Assignee: THE BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM
    Inventors: Jia Zhou, Chunyong Ding, Qiang Shen
  • Patent number: 10058583
    Abstract: The present invention relates to a composition for preventing or treating neurological diseases including an extract of Euphoria longan fruit, red sage and Gastrodia elata as an active ingredient. The composition of the present disclosure has a superior effect of inhibiting the activity of acetylcholinesterase (AChE), which hydrolyzes the neurotransmitter acetylcholine directly involved in impairment of cognitive function. In addition, the composition of the present disclosure is safe for the human body since the biologically safe extract of Euphoria longan fruit, red sage and Gastrodia elata is used as the active ingredient.
    Type: Grant
    Filed: March 29, 2012
    Date of Patent: August 28, 2018
    Assignee: VIROMED CO., LTD.
    Inventors: Doo Suk Lee, Dong Sik Kim, Seon Hee Kim
  • Patent number: 10034853
    Abstract: The present invention discloses a PPAR ?/? dual agonist and its application. The PPAR ?/? dual agonist comprises an effective amount of the compounds represented by formula I or/and its pharmaceutically acceptable derivative. Wherein. R1 is selected from alkoxyl or ester group; R2 is selected from hydroxyl or ester group. The PPAR ?/? dual agonist according to the present invention can be used for preparing drugs and functional foods for preventing or/and treating metabolic syndrome, especially glucose or/and lipid disorders, with extensive and bright prospects of application.
    Type: Grant
    Filed: April 15, 2014
    Date of Patent: July 31, 2018
    Assignee: Shanghai University of Traditional Chinese Medicine
    Inventors: Fujiang Guo, Cheng Huang, Li Feng, Yiming Li
  • Patent number: 10016474
    Abstract: An extract from leaves of mulberry is disclosed. The extract has an IC50 value sufficient to inhibit ?-glucosidase I. The extract may comprise 5-40% (w/w) total imino sugars and 20-70% (w/w) total amino acids. The extract may reduce the production of melanin for the treatment of such ailments or diseases caused by pigmentation as freckle, chloasma, striae gravidarum, sensile plaque and melanoma. The extract may also control blood glucose level.
    Type: Grant
    Filed: February 12, 2015
    Date of Patent: July 10, 2018
    Assignee: Botanic Century Beijing Co. Ltd.
    Inventors: Chen Xie, Yingshu Zou
  • Patent number: 10004781
    Abstract: A prescription of intravenous medication and its treatment method block heroin or morphine intoxication. The prescription of intravenous infusion includes Cerebrolysin, Piracetam, Cimetidine, Scopolamine Butylbromide, Nefopam, B.C Complex, Vitamin B1, Ascorbic Acid, Ketorolac, Guronsan, Hyoscine Butylbromide and Sukerin. The prescription activates a patient's liver and circulatory system to block drug intoxication. The treatment method for blocking drugs includes an acute withdrawal part, with the prescription of intravenous infusion injected and with the timing of drug administration and the safe dosage controlled according to clinical symptoms. An appropriate amount of a supplementary medicine such as Haloperidol is added, and the processes of detoxication, relieving symptoms, suppressing restlessness, and sobering are conducted to block acute withdrawal symptoms of an acute withdrawal addict quickly and successfully.
    Type: Grant
    Filed: January 19, 2016
    Date of Patent: June 26, 2018
    Inventor: En-Che Cheng
  • Patent number: 9956241
    Abstract: Disclosed are methods of enhancing neurocognitive function by administering of American Ginseng. Preferred dosages in the range of 5 to 50 mg total ginsenosides enhance cognitive function—including, improvement of working memory (WM) performance, attentional performance (e.g., Choice Reaction Time accuracy), and calmness.
    Type: Grant
    Filed: February 27, 2015
    Date of Patent: May 1, 2018
    Assignee: Naturex, S.A.
    Inventors: Andrew Scholey, Alvin Ibarra, Kan He, Marc Roller, Jacques Dikansky
  • Patent number: 9951148
    Abstract: The invention relates to a method for production of a preparation from a vegetable material, said preparation being enriched in a polysaccharide with a backbone comprising rhamnogalacturonan-I cores, said method comprising the steps: mixing the vegetable material with a polar alcoholic solvent; and separating a solid residue obtained in step a) from the solvent; and mixing the solid residue obtained in step b) with a buffered aqueous solution having a pH between 7 and 8. Also provided is a preparation containing rhamnogalacturonan-I pectins that can be obtained by this method and the use of such a preparation to modulate immune response.
    Type: Grant
    Filed: April 27, 2012
    Date of Patent: April 24, 2018
    Assignee: NutriLeads B.V.
    Inventors: Jari Helin, Jean Hypolites Koek
  • Patent number: 9937215
    Abstract: Composition comprising an anti-inflammatory plant extract from rosehips together with a cartilage-protective substance, and a method of producing the rosehip extract.
    Type: Grant
    Filed: December 19, 2008
    Date of Patent: April 10, 2018
    Assignee: Finzelberg GmbH & Co., KG
    Inventors: Bernd Walbroel, Björn Feistel, Ivo Pischel
  • Patent number: 9901608
    Abstract: Disclosed is a composition for enhancing alcohol metabolism in a subject, who overdrank, the composition comprises an effective amount of ginsenoside-free extract of steam-dried Korean ginseng berry (GFM) and one or more pharmaceutically or sitologically acceptable carriers. The composition of the present disclosure may be effective for alleviating hangover according to overdrink and for protecting liver from alcoholic injure.
    Type: Grant
    Filed: August 28, 2014
    Date of Patent: February 27, 2018
    Assignee: GANGNEUNG-WONJU NATIONAL UNIVERSITY INDUSTRY ACADEMY COOPERATION GROUP
    Inventor: Seong-Soo Joo
  • Patent number: 9901610
    Abstract: Disclosed are compositions containing: a) Phaseolus vulgaris extract; b) Cynara scolymus extract; c) Echinacea angustifolia extract; d) Vitis vinifera extract and optionally e) Panax ginseng extract, mixed with suitable excipients.
    Type: Grant
    Filed: October 10, 2013
    Date of Patent: February 27, 2018
    Assignee: INDENA S.P.A.
    Inventors: Ezio Bombardelli, Fabrizio Corti
  • Patent number: 9839660
    Abstract: The present invention provides a composition comprising Astragali Radix extract as an active ingredient. The composition can increase body energy consumption and muscle metabolism. The present invention also relates to pharmaceutical and food compositions which include a composition comprising the Astragali Radix extract. The pharmaceutical and food compositions also increase body energy consumption and muscle metabolism.
    Type: Grant
    Filed: November 29, 2010
    Date of Patent: December 12, 2017
    Assignee: AMOREPACIFIC CORPORATION
    Inventors: Pil Joon Park, Si Young Cho, Dae Bang Seo, Sang Jun Lee
  • Patent number: 9814749
    Abstract: The present invention relates to a composition for preventing or treating dementia containing an extract of Prunus mume (Fructus Mume), and the Prunus mume extract of the present invention has outstanding effects in improving spatial recognition ability and in normalizing hippocampal damage (normalizing ERK phosphorylation, increasing ChAT and normalizing NF-kappa B) induced by chronic vascular brain damage in a vascular dementia animal model, and hence can be used to advantage as a medicinal product for preventing or treating dementia diseases and as a functional health food for preventing or alleviating dementia diseases that accompany vascular brain damage such as vascular dementia.
    Type: Grant
    Filed: October 4, 2011
    Date of Patent: November 14, 2017
    Assignee: Korea Institute of Oriental Medicine
    Inventors: Won Kyung Jeon, Jung-Soo Han, Chang Hyun Han, Goya Choi
  • Patent number: 9789151
    Abstract: The present invention features a composition and method for reducing food intake. The composition of the invention is composed of yerbe maté extract, guarana extract, and damiana extract in combination with a dietary fiber.
    Type: Grant
    Filed: January 6, 2016
    Date of Patent: October 17, 2017
    Assignee: NATURES REMEDIES LTD.
    Inventors: Jason Christian Grovenor Halford, Trevor Rodney Jarman
  • Patent number: 9694043
    Abstract: A composition including Cuscuta japonica Choisy extract, or the extract of Rehmannia glutinosa Libschitz var. purpurea MAKINO and Cuscuta japonica Choisy is provided. The composition, which can be a pharmaceutical or food composition, is useful for preventing, ameliorating, or treating hearing loss. A method for ameliorating, preventing, or treating hearing loss, in particular, acoustic trauma, temporary or permanent hearing loss by effectively inhibiting the threshold shift induced by noise and the likes is disclosed.
    Type: Grant
    Filed: October 28, 2015
    Date of Patent: July 4, 2017
    Assignee: UNIVERSITY-INDUSTRY COOPERATION GROUP OF KYUNG HEE UNIVERSITY
    Inventors: Tong Ho Kang, Bin Na Hong
  • Patent number: 9675652
    Abstract: Compounds having unique properties are prepared from the herbal compositions described herein and comprise extracts derived from plants and fungi of the genera Panax, Ganoderma, and Saussurea. The compositions are useful in preventing, treating, relieving, and improving the quality-of-life of patients suffering from chronic diseases, such as liver diseases, cancer, cachexia, and immune system disorders.
    Type: Grant
    Filed: July 24, 2012
    Date of Patent: June 13, 2017
    Assignee: HXLS Charity Corp.
    Inventor: Andy Teh-An Huang
  • Patent number: 9670311
    Abstract: A polylactic polyester resin having a chemical structure represented by Formula (1), an acid value of 300 to 2,500 eq/106 g, a number average molecular weight of 2,000 to 50,000, and a lactic acid content percentage of not less than 40 weight %, Z—(O—(CH2CH2O)p—(CO—Y—O)q—X)r??(1) wherein Z is an r-valent organic group, Y is —CH(CH3)—, or a mixture of —CH(CH3)— and C2-10 linear or branched alkylene group, and X is a residue of a polybasic acid having 2 or more carboxyl groups, or hydrogen; each of X, Y, and Z may be one kind or a mixture of a plurality of different kinds; and p, q, and r are 0 or a positive integer, p has an average value of not less than 0.5, q has an average value of not less than 5, and r has an average value of not less than 3 and not more than 15.
    Type: Grant
    Filed: February 18, 2013
    Date of Patent: June 6, 2017
    Assignee: TOYOBO CO., LTD
    Inventors: Hideki Tanaka, Naoko Oda
  • Patent number: 9649350
    Abstract: Provided is a 15-PGDH activity adjusting function of a Dendropanax morbifera extract. More specifically, since it has been confirmed that the Dendropanax morbifera extract has an outstanding effect in suppressing 15-PGDH activity and so increasing PGE2, a composition of the present invention which contains the Dendropanax morbifera extract as an active ingredient has the advantage of being able to be used for producing a functional health food and a therapeutic agent for a disease associated with PGE2.
    Type: Grant
    Filed: November 28, 2014
    Date of Patent: May 16, 2017
    Assignee: Industry-Academic Coorperation Foundation, Chosun University
    Inventors: Cheol-Hee Choi, Hoon Cho, Young-Sook Moon, Ji-Won Han, Ju-Hee Han
  • Patent number: 9623253
    Abstract: Some implementations provide a method for treating urological disorders in a patient, the method including: placing an introducer into a patient's body through an incision site on the patient's body, the patient suffering from an urological disorder; placing an implantable wireless device into an inner lumen of the introducer, the implantable wireless device suitable to fit into the inner lumen and configured to receive electromagnetic energy non-inductively from a source located outside the patient's body; through the inner lumen of the introducer, positioning the implantable wireless device adjacent to or near one or more excitable tissue in the patient, the one or more excitable tissue regulating a nerve activity associated with the urological disorder; and causing neural modulation of the one or more excitable tissue through one or more electrodes on the implantable wireless device.
    Type: Grant
    Filed: March 14, 2014
    Date of Patent: April 18, 2017
    Assignee: Micron Devices, LLC
    Inventors: Laura Tyler Perryman, Chad Andresen
  • Patent number: 9610316
    Abstract: A medical composition for inhibiting the growth of cancer stem cells is disclosed. The medical composition is prepared by mixing herbal medicines with water or alcohol, followed by heating and extraction to obtain a filtrate. One of the medical compositions according to the present invention includes: Coptis chinensis, Scutellaria baicalensis, Phellodendron amourense, Gardenia jasminoides, Radix Glycyrrhizae, and Atractylodes japonica.
    Type: Grant
    Filed: December 23, 2013
    Date of Patent: April 4, 2017
    Assignee: NATIONAL TAIWAN NORMAL UNIVERSITY
    Inventors: Hsiu-Mei Hsieh, Chen-Yu Lee
  • Patent number: 9610463
    Abstract: Disclosed is a cosmetic or dermatological preparation that is obtainable by combining collagen and/or a derivative thereof, chitosan and/or a derivative thereof, glycosylaminoglycan and/or a derivative thereof with a peptide that is capable of promoting skin cell growth and/or with a composition which comprises glycoproteins 1 and 2 and ginseng and horsetail extracts.
    Type: Grant
    Filed: February 1, 2010
    Date of Patent: April 4, 2017
    Assignee: BEIERSDORF AG
    Inventors: Sven Gohla, Daniel Stangl
  • Patent number: 9597365
    Abstract: The present disclosure discloses a method for treating vascular inflammation, improving skin beauty and improving male sexual function of a subject by administering a ginseng berry extract to the subject.
    Type: Grant
    Filed: May 9, 2014
    Date of Patent: March 21, 2017
    Assignee: AMOREPACIFIC CORPORATION
    Inventors: Chan-Woong Park, Myeong Hoon Yeom, Nam Hoon Cho, Sang Jun Lee, Sang Min Lee, Jin Young Lee, Hee Yong Jeon, Young-Myeong Kim, Chun-Ki Kim, Young Deuk Choi
  • Patent number: 9517197
    Abstract: The present invention discloses a preparation method for toothpaste composition containing ganoderma lucidum component, wherein the ganoderma lucidum component is sporoderm-broken ganoderma lucidum spore, it comprises the following steps: (1) dissolve water, sorbitol, PEG-8, propylene glycol, sodium saccharine, sodium benzoate and the extract of opuntia in a toothpaste-making pot; (2) premix calcium hydrogen phosphate, hydrated silica, sodium lauryl sulfate, cellulose gum, hydroxyethyl cellulose, sporoderm-broken ganoderma lucidum spore, Panax notoginseng powder, and radix scutellariae root powder in powder tank evenly to form a mixture; (3) stir the mixture obtained in step (2) under vacuum and inhale into the toothpaste-making pot of step (1); control the vacuum degree at minus 0.098 to minus 0.1 Mpa and stir for 15 minutes; (4) inhale the essence into the toothpaste-making pot, stir for 10 minutes, and discharge.
    Type: Grant
    Filed: June 15, 2016
    Date of Patent: December 13, 2016
    Assignee: Jiangsu Daocheng Biotechnology Co., Ltd.
    Inventors: Zhengguo Gu, Yangchun Chen, Wei Zhang
  • Patent number: 9512453
    Abstract: A method for preparing a processed ginseng or a processed ginseng extract having increased contents of ginsenosides Rg3 and Rh2 by (a) inoculating an Aspergillus niger strain into a medium composed of ginseng and wheat bran; (b) culturing the strain of step (a); (c) purifying the cultured material of step (b) by ultrafiltration; (d) separating an enzyme from the purified material of step (c); (e) adding the enzyme of step (d) to ginseng or red ginseng; (f) fermenting the ginseng or red ginseng of step (e); (g) separating the fermented material of step (f) to obtain a supernatant; (h) concentrating the supernatant of step (g); (i) reacting the concentrate of step (h) with organic acid; and (j) neutralizing, filtering, purifying, concentrating and drying the reaction product of step (i).
    Type: Grant
    Filed: May 13, 2011
    Date of Patent: December 6, 2016
    Assignee: GREEN CROSS WELLBEING CORPORATION
    Inventors: Young-Hyo Yoo, Sun-Ok Kim, Jung Hyo Choi, Soo-Hyun Bae, Sun Kyu Park, Jeom Yong Kim
  • Patent number: 9474735
    Abstract: A pharmaceutical preparation containing polymeric compounds as shown in the specification. This preparation can be used to improve liver function and treat liver disease, and promoting liver tissue regeneration.
    Type: Grant
    Filed: December 17, 2014
    Date of Patent: October 25, 2016
    Assignee: Industrial Technology Research Institute (ITRI)
    Inventors: Shau-Feng Chang, Chun-Hsien Ma, Kuo-Yi Yang, Chien-Tung Lin, Shyh-Horng Lin, Kai-Wen Huang
  • Patent number: 9474778
    Abstract: Herbal MDR for the prevention and treatment of atherosclerosis which includes a summary of the genus Gentiana and a summary of the genus Hippocratea, in particular, gentiana lutea and hippocratea excelsa. Comes as a solid, preferably capsules. Herbal composition is obtained by selecting Rhizome and root of Gentiana lutea blending by centrifugation, and separating the supernatant which mingles with the alcoholic extract of Hippocratea excelsa. Applies in the prevention and treatment of atherosclerosis, as well as in atherosclerotic Occlusive disease complications such as blockage of coronary arteries and arteries that supply the heart.
    Type: Grant
    Filed: March 9, 2012
    Date of Patent: October 25, 2016
    Inventor: Jose Arturo Castañeda Miranda
  • Patent number: 9415081
    Abstract: The present invention relates to a composition for preventing or treating acquired immunodeficiency syndrome (AIDS), comprising one or more of the following: a homogenous cell line, and a lysate, an extract and a culture thereof as an active ingredient. The homogenous cell line, the lysate, the extract and the culture thereof, which are derived from a natural product, minimize adverse side effects of prior therapeutic agents and safe for the human body. Further, they effectively increase the count of T cells such as CD4+ T cells and decrease the number of HIVs, thereby preventing opportunistic infection, dysneuria, and neoplaia caused by immune incompetence, and ultimately the risk of death. Therefore, they are useful in preventing and treating AIDS, and relieving symptoms of AIDS.
    Type: Grant
    Filed: March 14, 2013
    Date of Patent: August 16, 2016
    Assignees: UNHWA CORPORATION
    Inventors: Sun Mi Hong, Eun Kyong Lee, Young Woo Jin
  • Patent number: 9314490
    Abstract: The present invention relates to compositions of rosmarinic acid or its derivatives and to the use of a hydrolytic enzyme or of microorganism containing or producing hydrolytic enzymes in these compositions. The invention also pertains to methods for improving the biological effects of the rosemary extracts and for administering such compositions to a human or animal subject for improving the skin, coat, hair or health of the subject.
    Type: Grant
    Filed: September 18, 2013
    Date of Patent: April 19, 2016
    Assignees: Nestec S.A., L'Oréal
    Inventors: Vanessa Crespy, Isabelle Castiel, Rachid Bel-Rhlid, Nicolas Page, Thomas Raab
  • Patent number: 9283203
    Abstract: This invention relates to compositions, and methods of use thereof, for (i) enhancing executive cognitive function(s) (for example, decision making, planning, working memory, multitasking, judgment, numerical problem-solving, reading comprehension), and/or (ii) increasing blood flow in brain vasculature, comprising administering to a subject in need thereof, certain polyphenols such as flavanols, procyanidins, or pharmaceutically acceptable salts or derivatives thereof.
    Type: Grant
    Filed: June 15, 2007
    Date of Patent: March 15, 2016
    Assignee: MARS, INCORPORATED
    Inventors: Stephen French, Amar P. Inamdar, Ian Andrew Macdonald, Susan T. Francis
  • Patent number: 9278104
    Abstract: A composition containing nelumbo extract reduces and/or eliminates one or more risk factors associated with Metabolic syndrome. The composition also includes optionally one of more components selected from the group consisting of vitamins, cholesterol lowering agents, lipid lowering agents, and glucose lowering agent. Also described is a method of reducing and/or eliminating risk factors associated with Metabolic syndrome in a subject through the administration of the nelumbo extract. The nelumbo extract supplement is administered orally, intravenously, or subcutaneously. In one embodiment, a daily dose of 10-1,000 mg of the extract supplement is administered to the subject for a period of 6 weeks to 6 months.
    Type: Grant
    Filed: October 26, 2011
    Date of Patent: March 8, 2016
    Assignee: IN Ingredients, Inc.
    Inventor: Tim Romero
  • Patent number: 9238051
    Abstract: Disclosed herein are methods for treating mammals with HIV/AIDS comprising administering a therapeutically effective amount of a composition comprising an extract of Rubia cordifolia. The extract is preferably an alcohol extract, an aqueous extract, or mixtures thereof. The alcohol preferably comprises ethanol, isopropyl alcohol, or mixtures thereof.
    Type: Grant
    Filed: May 10, 2011
    Date of Patent: January 19, 2016
    Assignee: THE FLORIDA INTERNATIONAL UNIVERSITY BOARD OF TRUSTEES
    Inventors: Madhavan P. N. Nair, Zainulabedin M. Saiyed, Nimisha H. Gandhi
  • Patent number: 9233061
    Abstract: A cosmetic composition according to the present invention may prevent the precipitation of caffeine at a low temperature, and thus may comprise a high concentration of caffeine that is effective in promoting lipolysis. Caffeine is known to promote lipolysis when applied to a human body. The cosmetic composition of the present invention may comprise a high concentration of caffeine, and thus can be valuably use in cosmetics or the like that requires effects of caffeine such as slimming effects, effect of relief from facial swelling or the like.
    Type: Grant
    Filed: November 16, 2012
    Date of Patent: January 12, 2016
    Assignee: AMOREPACIFIC CORPORATION
    Inventors: Dong Hyuk Jang, Hwa Young Shin, Chang Hoon Park, Sang Hoon Han
  • Patent number: 9220741
    Abstract: A method of enhancing weight loss involves administering to an overweight human a weight loss product that includes a mixture of Alchemilla vulgaris, Olea europaea, Cuminum cyminum, and Mentha longiflora (in the weight proportion 12:10:5:4), to which is added at least one herbal ingredient such as Malpighia glabra. As additional ingredients at least one of Conjugated linoleic acid and caffeine can be provided, with the caffeine in the form of caffeine anhydrous, Coffea Arabica, Coffea canephora, Camellia sinensis, Ilex paraguariensis, Guarana, Theobroma cacao, and kola nut. In one preferred embodiment the method involves administering, optionally in tablet form, a composition consisting essentially of the mixture of Alchemilla vulgaris, Olea europaea, Cuminum cyminum, and Mentha longiflora; caffeine anhydrous; Vitamin C; Lyceum barbarum; Malpighia glabra; Blueberry; Punica granatum; Bilberry; and one or more excipients. Other ingredients may be used as well in accordance with specific disclosed formulations.
    Type: Grant
    Filed: August 30, 2011
    Date of Patent: December 29, 2015
    Assignee: Northern Innovations and Formulations Corp.
    Inventors: Shawn Shirazi, James Akrong, Phil Apong, Raza Bashir, Craig Wissent
  • Patent number: 9220739
    Abstract: An all-natural, multi-purpose body powder comprised of Boric Acid, Organic Lavender, Tea Tree, Eucalyptus and Peppermint. The ratios of Boric Acid to Organic Lavender and Tea Tree are 288:1. The ratios of Boric Acid to Organic Eucalyptus and Peppermint are 1728:1. All of said ingredients create an environment that bacteria cannot grow in, wherein body, foot and shoe odor is prevented.
    Type: Grant
    Filed: November 5, 2013
    Date of Patent: December 29, 2015
    Inventor: Shaun Hunter
  • Patent number: 9211310
    Abstract: The present invention relates to a use of Chinese medicine composition in preparation of medicine for secondary prevention of myocardial infarction. Said Chinese medicine composition is prepared from a formula comprising the crude drugs by the following weight percentages: Radix Astragali 22.2%˜66.8%, Radix Salviae Miltiorrhizae 11.6%˜33.4%, Radix Notoginseng 2.5%˜13.5%, and Lignum Dalbergiae Odoriferae 14.5%˜44.3%.
    Type: Grant
    Filed: June 28, 2011
    Date of Patent: December 15, 2015
    Assignee: TASLY PHARMACEUTICAL GROUP CO., LTD
    Inventors: Boli Zhang, Hongcai Shang, Chen Yao, Baoyan Liu, Weiliang Weng, Yuxia Zhao, Guohua Dai, Xiumei Gao, Ming Ren, Junhua Zhang, Hongbo Cao, Jingyuan Mao, Xuejun Hu, Zhisheng Jin, Junping Zhang, Yiyu Cheng, Xijun Yan, Jiazhen Qu, Hui Wang, Hongjuan Xu, Wenke Zheng
  • Patent number: 9205123
    Abstract: A capsule of compound danshen dripping pills are disclosed. The color of the capsule's shell is orange, yellow, green or blue and all of these colors are in the wavelength range of 446-620 nm.
    Type: Grant
    Filed: February 17, 2011
    Date of Patent: December 8, 2015
    Assignee: Tasly Pharmaceutical Group Co., Ltd.
    Inventors: He Sun, Shuiping Zhou, Lanlan Zhang, Zhijuan Huang, Zhaohui Song
  • Patent number: 9173921
    Abstract: Disclosed are a method of promoting hair growth or preventing hair loss in a mammal. In one aspect, the method includes administering interdermally or subcutaneously an agent containing an active ingredient comprising bFGF and a pharmaceutically acceptable substance, wherein bFGF is administered in a dose of 1 ?g to 100 ?g per 1 cm2 of the target area of hair growth treatment or hair loss prevention and a composition for use in the method.
    Type: Grant
    Filed: March 23, 2015
    Date of Patent: November 3, 2015
    Inventor: Jaehyun Lim