Plant Material Or Plant Extract Of Undetermined Constitution As Active Ingredient (e.g., Herbal Remedy, Herbal Extract, Powder, Oil, Etc.) Patents (Class 424/725)
  • Patent number: 11337905
    Abstract: Embodiments of the invention are directed to compositions containing cannabinoid, cannabidiol, or cannabidiol analog for lightening or whitening skin, and methods for lightening skin tone or whitening skin by administering compositions containing cannabinoid, cannabidiol, or cannabidiol analog to the skin.
    Type: Grant
    Filed: January 14, 2019
    Date of Patent: May 24, 2022
    Assignee: Truetiva, Inc.
    Inventor: J. Phillip Kennedy
  • Patent number: 11340211
    Abstract: The invention relates to an in vitro method for evaluating digestive efficiency (DE) of poultry, in particular chickens, by measuring color of a sample of liquid fraction of blood of said poultry.
    Type: Grant
    Filed: September 13, 2019
    Date of Patent: May 24, 2022
    Assignees: UNIVERSITE DE TOURS, INSTITUT NATIONAL DE RECHERCHE POUR LAGRICULTURE, L'ALIMENTATION ET L'ENVIRONNEMENT
    Inventors: Sandrine Grasteau, Elisabeth Duval, Stéphane Beauclercq
  • Patent number: 11331301
    Abstract: A method of treating a malignant disease in a subject in need thereof is provided. The method comprising administering to the subject a therapeutically effective amount of a first liquid chromatography fraction of a cannabis extract comprising at least 75% tetrahydrocannabinolic acid (THCA), and a therapeutically effective amount of a second liquid chromatography fraction of a cannabis extract comprising at least 75% cannabigerolic acid (CBGA), wherein the first liquid chromatography fraction comprises cannabis derived active ingredients other than the THCA, and the second liquid chromatography fraction comprises cannabis derived active ingredients other than the CBGA, thereby treating the malignant disease in the subject.
    Type: Grant
    Filed: March 5, 2018
    Date of Patent: May 17, 2022
    Assignees: The State of Israel, Ministry of Agriculture & Rural Development, Agricultural Research Organization (ARO) (Volcani Center), Mor Research Applications Ltd.
    Inventors: Hinanit Koltai, Yoram Kapulnik, Dvora Namdar, Moran Mazuz, Ido Laish, Timna Naftali
  • Patent number: 11311591
    Abstract: The invention relates to a use of Copaifera oleoresin for producing a medicament for preventing and/or treating pathologies of the prostate, particularly benign prostatic hyperplasia and/or prostate cancer.
    Type: Grant
    Filed: March 20, 2018
    Date of Patent: April 26, 2022
    Assignee: PIERRE FABRE MEDICAMENT
    Inventor: Christel Fiorini-Puybaret
  • Patent number: 11311585
    Abstract: The purpose of the present invention is to provide a substance related to the stabilization of capillary blood vessels. This invention is based on the discovery that an extract from a plant selected from the group consisting of Calendula officinalis, Siberian ginseng, and Cistanche salsa increases gene expression of VE-cadherin or integrin ?5.
    Type: Grant
    Filed: November 15, 2018
    Date of Patent: April 26, 2022
    Assignee: Shiseido Company, Ltd.
    Inventors: Kentaro Kajiya, Yuuko Matsumoto
  • Patent number: 11311594
    Abstract: Disclosed is a combination of extracts of Cynara cardunculus and Citrus bergamia which are useful for the prevention and treatment of hepatic steatosis and other disorders correlated with dyslipidaemic conditions.
    Type: Grant
    Filed: April 10, 2018
    Date of Patent: April 26, 2022
    Assignee: Herbal & Antioxident Derivatives, S.R.L.
    Inventors: Ezio Bombardelli, Vincenzo Mollace
  • Patent number: 11299470
    Abstract: Chromatography systems and methods for using carbon dioxide to separate one or more cannabis-derived compounds from other components of a mixture are generally described. Some of the methods described herein comprise transporting a mixture comprising a first cannabis-derived compound and one or more other components through a chromatography column containing a stationary phase comprising a packing material. In some embodiments, the mixture is transported through the column within a mobile phase that comprises carbon dioxide (e.g., supercritical CO2, liquid CO2). The mobile phase may be substantially free of a co-solvent that is in liquid phase at standard room temperature and pressure. In some embodiments, the mobile phase is free of any co-solvent and comprises 100 vol % carbon dioxide.
    Type: Grant
    Filed: August 7, 2018
    Date of Patent: April 12, 2022
    Assignee: Massachusetts Institute of Technology
    Inventors: Clark K. Colton, John M. Moses, Veronica M. Wilson, William H. Dalzell, Mariya Layurova, Tony J. Elian, Truong H. Cai, John MacKay
  • Patent number: 11285092
    Abstract: A cosmetic concentrate base composition and cosmetic compositions for use as creams or lotions utilizing the same, the cosmetic concentrate base composition including approximately 20% to 25% by weight of a first component, the first component being a phospholipid component; approximately 10% to 40% by weight of a second component, the second component being a lipid component; and approximately 4% to 5% by weight of a third component, the third component being a hydrophilic component.
    Type: Grant
    Filed: August 8, 2019
    Date of Patent: March 29, 2022
    Assignee: Sobel Brands, LLC
    Inventors: Howard Sobel, John Kressaty
  • Patent number: 11279674
    Abstract: A method for treating phytophotodermatitis including the steps of applying an isothiocyanate functional surfactant to an area affected by phytophotodermatitis, wherein said isothiocyanate functional surfactant comprises at least one isothiocyanate functional group associated with an aliphatic and/or aromatic carbon atom of the isothiocyanate functional surfactant.
    Type: Grant
    Filed: May 12, 2020
    Date of Patent: March 22, 2022
    Assignee: The William M. Yarbrough Foundation
    Inventor: Michael E. Silver
  • Patent number: 11266704
    Abstract: A total flavonoid extract from Gynura formosana Kitam., comprising 80-85% of rutin. A preparation method comprises selecting a complex enzyme consisting of a specific composition and ratio of enzymes for enzymatic hydrolysis, extracting and concentrating by a macroporous resin, and separating and purifying by a macroporous resin. The extract has therapeutic effect on non-alcoholic fatty liver disease.
    Type: Grant
    Filed: March 17, 2020
    Date of Patent: March 8, 2022
    Assignee: ZHANGZHOU PIEN TZE HUANG PHARMACEUTICAL CO., LTD.
    Inventors: Zhiliang Chen, Jinming Huang, Juan Yu, Fei Hong, Zhaoqiang Zhang, Xuxin Li
  • Patent number: 11266634
    Abstract: Human therapeutic treatment compositions comprise at least two of a curcumin component, a harmine component, and an isovanillin component, and preferably all three in combination. The agents are effective for the treatment of human conditions, especially human cancers.
    Type: Grant
    Filed: August 21, 2020
    Date of Patent: March 8, 2022
    Assignee: Ankh Life Sciences Limited
    Inventors: Gene H. Zaid, Thomas W. Burgoyne
  • Patent number: 11266707
    Abstract: Disclosed herein are methods of treating or preventing complications associated with a SARS-CoV-2 infection, comprising: administration of a combination comprising: a) Green Tea and/or extract thereof; b) Blueberry and/or extract thereof; c) Nigella sativa and/or extract thereof; and d) broccoli and/or extract thereof in an amount and frequency sufficient to treat or prevent complications associated with said SARS-CoV-2 infection.
    Type: Grant
    Filed: May 4, 2020
    Date of Patent: March 8, 2022
    Assignee: Therapeutic Solutions International, Inc.
    Inventors: Thomas E Ichim, Timothy G Dixon
  • Patent number: 11270882
    Abstract: A film formation apparatus is configured to supply mist of a solution to a surface of a substrate so as to epitaxially grow a film on the surface of the substrate. The film formation apparatus may be provided with: a furnace configured to house and heat the substrate; a reservoir configured to store the solution; a heater configured to heat the solution in the reservoir; an ultrasonic transducer configured to apply ultrasound to the solution in the reservoir so as to generate the mist of the solution in the reservoir; and a mist supply path configured to carry the mist from the reservoir to the furnace.
    Type: Grant
    Filed: January 13, 2020
    Date of Patent: March 8, 2022
    Assignees: DENSO CORPORATION, NATIONAL UNIVERSITY CORPORATION KYOTO INSTITUTE OF TECHNOLOGY
    Inventors: Tatsuji Nagaoka, Hiroyuki Nishinaka, Daisuke Tahara, Masahiro Yoshimoto
  • Patent number: 11253467
    Abstract: A method of preparing a skin treatment that includes preparing an extract of Arnica montana by mixing Arnica montana with ethyl alcohol, and filtering out the solids thereby resulting in liquid Arnica montana extract. In a first dilution, diluting the liquid Arnica montana extract with distilled water resulting in a first diluted Arnica montana extract. In a second dilution, diluting the first diluted Arnica montana extract with alkaline water resulting in a liquid skin treatment.
    Type: Grant
    Filed: December 3, 2019
    Date of Patent: February 22, 2022
    Assignee: SLC Skin LLC.
    Inventors: Stacy Lynn Charlton, Gary S. Huvard, Maura Fierro
  • Patent number: 11253532
    Abstract: An object of the present invention is to provide a composition for stimulating an increase in an androgen. The composition for stimulating an increase in an androgen contains compound K. The composition for stimulating an increase in an androgen contains a fermentation product and/or enzymatically degraded product of ginseng as an active ingredient.
    Type: Grant
    Filed: October 15, 2020
    Date of Patent: February 22, 2022
    Assignee: Kobayashi Pharmaceutical Co., Ltd.
    Inventors: Kazuaki Iguchi, Hiroyuki Fukami
  • Patent number: 11234941
    Abstract: The invention relates to nanoparticles comprising a solid matrix, wherein the solid matrix comprises albumin and certain xanthophylls, and wherein the xanthophyll is distributed throughout the solid matrix. The present invention also relates to the method for obtaining the nanoparticles and to the products and compositions incorporating them.
    Type: Grant
    Filed: March 14, 2018
    Date of Patent: February 1, 2022
    Assignee: GAT Therapeutics S.L.
    Inventors: Xavier Álvarez Micó, Eugenia Ruiz Canovas, Ariadna Emeric Casterà, Jaume Mercadé Roca, Olga Durany Turk, Jordi Segura De Yebra
  • Patent number: 11224587
    Abstract: A process for extracting a botanical organic compound from cannabis with subcritical liquid carbon dioxide includes providing a pressurizable extraction vessel. The cannabis is placed within the pressurizable extraction vessel, whereupon the extraction vessel is filled with liquid carbon dioxide under subcritical conditions. The cannabis is then allowed to be in contact with the subcritical liquid carbon dioxide for a selected period of time so as to extract at least a portion of the botanical organic compounds from the cannabis into the subcritical liquid carbon dioxide. The subcritical liquid carbon dioxide containing the botanical organic compound is then removed from the extraction vessel, and the liquid carbon dioxide is separated from the botanical organic compound.
    Type: Grant
    Filed: January 7, 2020
    Date of Patent: January 18, 2022
    Assignee: Cool Clean Technologies, LLC
    Inventors: Nelson W. Sorbo, Jon R. Turner, Jon Wikstrom
  • Patent number: 11219654
    Abstract: A total flavonoid extract from Gynura formosana Kitam., comprising 80-85% of rutin. A preparation method comprises selecting a complex enzyme consisting of a specific composition and ratio of enzymes for enzymatic hydrolysis, extracting and concentrating by a macroporous resin, and separating and purifying by a macroporous resin. The extract has therapeutic effect on non-alcoholic fatty liver disease.
    Type: Grant
    Filed: March 17, 2020
    Date of Patent: January 11, 2022
    Assignee: ZHANGZHOU PIEN TZE HUANG PHARMACEUTICAL CO., LTD.
    Inventors: Zhiliang Chen, Jinming Huang, Juan Yu, Fei Hong, Zhaoqiang Zhang, Xuxin Li
  • Patent number: 11213558
    Abstract: The present invention relates generally to improved methods for the extraction and isolation of cannabinoids from hemp. More particularly, the present invention relates to a series of extraction and isolation processes employed to selectively enhance recovery of non-psychoactive cannabinoids and the like, from cannabis materials and extracts, while removing undesirable naturally occurring components that may be present including colorants, carbohydrates, sugars and waxes, and the like, as well as contaminants that may be present in source materials including bactericides, fungicides, insecticides, plant growth regulators, environmental pollutants, and processing aids, and the like. The present invention further relates to an isolate obtained using a series of extraction and isolation processes that has extremely high cannabinoid content present in a stable, flowable liquid form that is essentially free of detectable levels of psychoactive cannabinol components.
    Type: Grant
    Filed: May 16, 2018
    Date of Patent: January 4, 2022
    Assignee: Orochem Technologies, Inc.
    Inventors: Anil Rajaram Oroskar, David W. House, Kashif Shan, Rajesh Kumar Gupta
  • Patent number: 11213543
    Abstract: A formulation to increase the ratio of gastrointestinal microbiota in phylum Bacteroidetes to microbiota of Firmicutes phylum preferably includes about 20-60 mg/kg of body weight of fermentable fiber, about 10-30 mg/kg of body weight of beta glucan and about 20-60 mg/kg of body weight of blueberry extracts or any fruit or berry ingredient preparation containing similar phenolics. This formulation is preferably used to control body weight, body composition, and blood glucose regulation, preferably in humans, and is preferably administered orally, preferably twice per day.
    Type: Grant
    Filed: August 20, 2019
    Date of Patent: January 4, 2022
    Assignee: THE NATURE'S BOUNTY CO.
    Inventors: Mark L. Heiman, Dean P. Stull, Justin W. Peno
  • Patent number: 11213465
    Abstract: Disclosed is an apparatus and methods for its use that is configured to be used to treat various skin conditions. The apparatus includes a water-permeable absorbent material and a plant material comprising a water-soluble skin-active ingredient. The plant material is enclosed within the water-permeable absorbent material, and the water-permeable absorbent material is configured to absorb water and allow the absorbed water to contact the plant material so as to release the active ingredient from the plant material. The active ingredient is then absorbed by the absorbent material, which is then topically applied to skin in need of skin treatment.
    Type: Grant
    Filed: February 24, 2020
    Date of Patent: January 4, 2022
    Assignee: MARY KAY INC.
    Inventors: Daniel Chen, James Swanzy
  • Patent number: 11207364
    Abstract: The invention discloses a method for treating benign prostatic hyperplasia (BPH) using a burdock extract. The burdock extract is administered to a subject in need thereof to decrease prostate size of the subject. The burdock extract is obtained by extracting a sample of dried burdock seed using an extractant being water or an aqueous ethanol solution.
    Type: Grant
    Filed: June 10, 2020
    Date of Patent: December 28, 2021
    Assignee: KANG PIN TECHNOLOGY CO., LTD.
    Inventors: Fu-An Chen, Ya-Lan Yang, Chun-Che Sung, Yu-Syuan Huang
  • Patent number: 11202771
    Abstract: A relatively dry, relatively free flowing cannabinoid concentrate composition having a plant extract and a thickening agent. The cannabinoid concentrate composition may have a variety of cannabinoids, drying agents, flowing agents, and/or stabilization agents. The mixture may be a dry powder formulation similar to the consistency of flour or sand. The mixture may comprise a cannabinoid raffinate, an isolated cannabinoid, maltodextrin, and or silica.
    Type: Grant
    Filed: January 31, 2019
    Date of Patent: December 21, 2021
    Assignee: TREEHOUSE BIOTECH, INC.
    Inventors: Jacob Black, Robert Davis, Sean Colvin, Thomas Smeltzer, John Evanyo
  • Patent number: 11197833
    Abstract: An example blended oil composition includes a combination of Cannabidiol (CBD) oil extracted from Cannabis sativa, curcumin oil including one or more curcuminoids from turmeric rhizomes, and ginsenoside oil including one or more ginsenosides from at least one of Panax ginseng and P. quinquefolius. The Cannabis sativa comprises at least one of C. sativa, C. indica, and C. ruderalis. An example method of producing CBD oil is also disclosed.
    Type: Grant
    Filed: July 12, 2019
    Date of Patent: December 14, 2021
    Assignee: BRIGHT GREEN CORPORATION
    Inventor: V. Hari
  • Patent number: 11191795
    Abstract: The present invention provides herbal formulations, methods for their preparation, and methods of treating herpes simplex. The formulations can provide good permeability and bioavailability at the target site.
    Type: Grant
    Filed: February 20, 2019
    Date of Patent: December 7, 2021
    Inventor: Beatriz Eugenia Carrasco Niño
  • Patent number: 11191796
    Abstract: The present disclosure includes a nozzle and methods for using the nozzle in ways that may increase the efficiency of extraction of essential elements from plant matter. The nozzle may also be used to increase the efficiency of drying solvent saturated plant matter after an extraction has been completed. The nozzle may include an elongated tube with a plurality of holes that allow solvent and/or a gas to be provided or pumped/provided into an apparatus that includes plant matter. Nozzles consistent with the present disclosure may be optimized for extracting cannabis from cannabis plant matter or from other types of plants that include cannabinoids. In certain instances, nozzles may also be used when processing cannabinoid containing concentrates that were extracted from plant matter using any type of extraction technique.
    Type: Grant
    Filed: April 1, 2019
    Date of Patent: December 7, 2021
    Inventor: Robert James Rapp
  • Patent number: 11191800
    Abstract: The invention is directed to an aqueous extract of Eruca sativa (arugula) leaves that has antimicrobial activity on Gram-positive bacteria and mycoplasmas. The extract may be purified away from solid or insoluble components, standardized based on the weight of its non-aqueous or solid content, assayed for antimicrobial activity, and provided in an aseptic or sterile form for pharmaceutical use. It may be used to kill or inhibit the growth of microorganisms such as Gram positive bacteria, promote wound healing, or as prophylaxis against host colonization or infection by a microorganism.
    Type: Grant
    Filed: October 2, 2018
    Date of Patent: December 7, 2021
    Assignee: Imam Abdulrahman Bin Faisal University
    Inventors: Ines Mohsen Hammami, Azzah Ibrahim Alghamdi
  • Patent number: 11185566
    Abstract: A total flavonoid extract from Gynura formosana Kitam., comprising, in weight percent, 80-85% of rutin. A method for preparing the total flavonoid extract from Gynura formosana Kitam. comprises solvent extraction, complex enzymatic hydrolysis, and separation and purification by a macroporous resin. The total flavonoid extract from Gynura formosana Kitam. is used to prepare a drug or health product related to alcoholic fatty liver disease.
    Type: Grant
    Filed: March 17, 2020
    Date of Patent: November 30, 2021
    Assignee: Zhangzhou Pien Tze Huang Pharmaceutical Co., Ltd.
    Inventors: Zhiliang Chen, Jinming Huang, Fei Hong, Juan Yu, Zhiyi Luo, Xuxin Li
  • Patent number: 11185565
    Abstract: In an embodiment, the present disclosure pertains to a dietary supplement including berberine in an amount up to about 1500 mg, cinnamon in an amount up to about 300 mg, chromium in an amount up to about 300 mcg, milk thistle in an amount up to about 150 mg, and pyrroloquinoline quinone disodium (PQQ) in an amount up to about 30 mg. Additionally, the present disclosure relates to a method for managing weight, maintaining healthy blood sugar levels, preventing diabetes, or alleviating symptoms associated with diabetes, including administering a composition to a subject. In some embodiments, the composition includes berberine in an amount up to about 1500 mg, cinnamon in an amount up to about 300 mg, chromium in an amount up to about 300 mcg, milk thistle in an amount up to about 150 mg, and PQQ in an amount up to about 30 mg.
    Type: Grant
    Filed: December 31, 2019
    Date of Patent: November 30, 2021
    Assignee: GM Pharmaceuticals, Inc.
    Inventor: Odes W. Mitchell
  • Patent number: 11180781
    Abstract: The present disclosure relates to the field of commercial scale production and processing of biosynthetic cannabinoids produced by growing genetically modified microalgae in a photo-bioreactor to a produce biosynthetic cannabinoids, separating a liquid nutrient medium from the genetically modified microalgae, and extracting the biosynthetic cannabinoids to produce an extracted biosynthetic cannabinoid, then distilling the extracted biosynthetic cannabinoid to produce the biosynthetic cannabinoid distillate. Biosynthetic cannabinoid distillates may be used foodstuffs, beverages, nanoemulsions, spray-dried water-soluble powders, cosmetics, or topicals.
    Type: Grant
    Filed: August 11, 2020
    Date of Patent: November 23, 2021
    Assignee: INSECTERGY, LLC
    Inventor: Daniel Michael Leo
  • Patent number: 11173172
    Abstract: The present invention provides a composition for topical administration of a polyhydroxy acid, such as lactobionate and especially zinc lactobionate, and low pH to an external body surface such as skin. The composition is designed to be highly effective in delivering low pH and zinc lactobionate across the layers of the skin to more effectively treat and prevent skin conditions involving a defective skin barrier such as eczema and severe dry skin.
    Type: Grant
    Filed: May 10, 2018
    Date of Patent: November 16, 2021
    Assignee: HYPHENS PHARMA PTE. LTD.
    Inventors: Kevin Hammond, Adrian Davis
  • Patent number: 11166972
    Abstract: Disclosed are compositions comprising nicotinamide riboside and a urolithin. The compositions are useful as medicaments, for example, for treating muscle-related pathological conditions, neurodegenerative diseases, and/or mitochondrial diseases, and as dietary supplements, functional foods and beverages, and as specialized nutrition or medical foods.
    Type: Grant
    Filed: December 23, 2016
    Date of Patent: November 9, 2021
    Assignee: Amazentis SA
    Inventors: Penelope Andreux, Christopher L. Rinsch
  • Patent number: 11160795
    Abstract: The present disclosure provides methods of treating tuberous sclerosis complex comprising administering cannabidiol and everolimus.
    Type: Grant
    Filed: March 1, 2021
    Date of Patent: November 2, 2021
    Assignee: GW Research Limited
    Inventors: Geoffrey Guy, Volker Knappertz, Eduardo Dunayevich, David Critchley
  • Patent number: 11160778
    Abstract: The present invention refers to a composition for use in the prevention and/or treatment of orogastrointestinal mucositis induced by oncologic treatments. It also refers to the use of said composition for preparing a medicament for the prevention and/or treatment of said orogastrointestinal mucositis. Furthermore, it refers to a method of preventing and/or treating of said orogastrointestinal mucositis in which said composition is administered to a subject in need thereof.
    Type: Grant
    Filed: July 30, 2018
    Date of Patent: November 2, 2021
    Assignee: MUCOSA INNOVATIONS, S.L.
    Inventor: Deborah Rodriguez Vilaboa
  • Patent number: 11154579
    Abstract: The present invention is a process for producing various types of cannabis extract from harvested cannabis. A quantity of harvested cannabis, which typically includes the inflorescence, floral leaves, and small stems of a flowering cannabis plants, is pre-frozen. The harvested cannabis is first subjected to cryogenic grinding to produce pulverized cannabis. The pulverized cannabis is then subjected to alcohol extraction to produce an initial cannabis extract, which can be subjected to one of several forms of further processing according to the desired chemical profile of the final product. The initial cannabis extract may then be subjected to chemical processing that promote the conversion of THCA to ?9 THC; the conversion of THCVA to THCV; the conversion of THCA to cannabinol (“CBN”); or the conversion of THCA to ?8-THC.
    Type: Grant
    Filed: November 5, 2019
    Date of Patent: October 26, 2021
    Assignee: Jenny's Rose, LLC
    Inventor: James Castillo
  • Patent number: 11154567
    Abstract: A method for treatment of a liver disease, the method including administering kinsenoside to a patient in need thereof.
    Type: Grant
    Filed: February 3, 2020
    Date of Patent: October 26, 2021
    Assignee: HUAZHONG UNIVERSITY OF SCIENCE AND TECHNOLOGY
    Inventors: Yonghui Zhang, Ming Xiang, Tingting Liu
  • Patent number: 11154531
    Abstract: A method of treating coronavirus infection, comprising administering to a subject in need thereof an effective amount of a composition, wherein the composition comprises one or more compounds of Formula (I): or a pharmaceutically acceptable salt thereof.
    Type: Grant
    Filed: September 8, 2020
    Date of Patent: October 26, 2021
    Assignee: SYNEURX INTERNATIONAL (TAIWAN) CORP.
    Inventors: Guochuan Emil Tsai, Yi-Wen Mao, Lu-Ping Lu, Wei-Hua Chang, Han-Yi Hsieh, Jhe Wei Hu, Tsai-Miao Shih, ChanHui Huang
  • Patent number: 11155524
    Abstract: Methods of producing an amino acid nitrate supplement drink suitable for human consumption are provided. The methods comprise providing a solid nitrate salt of an amino acid and adding an amount of water to the solid nitrate salt of the amino acid to produce the amino acid and nitrate drink, wherein the amount of water is sufficient to dissolve the solid nitrate salt of the amino acid. In particular implementations, the solid nitrate salt of an amino acid is selected from the group consisting of: creatine nitrate, arginine nitrate, leucine nitrate, isoleucine nitrate, valine nitrate, cysteine nitrate, glycine nitrate, agmatine nitrate, beta-alanine nitrate, N-acetyl cysteine nitrate, aspartic acid nitrate, lysine nitrate, histidine nitrate, norvaline nitrate, ornithine nitrate, glutamine nitrate, citrulline nitrate, and betaine nitrate.
    Type: Grant
    Filed: June 4, 2020
    Date of Patent: October 26, 2021
    Assignee: ThermoLife International, LLC
    Inventors: Ronald Kramer, Alexandros Nikolaidis
  • Patent number: 11154580
    Abstract: Proposed is a composition for preventing, ameliorating or treating acne symptoms including a Sesamum indicum seed extract, a Quercus robur bark extract and a Houttuynia cordata extract as active ingredients, and at least one natural substance of a Cirsium japonicum extract and Thuja orientalis as an additional active ingredient. The composition for preventing, ameliorating or treating acne symptoms contains, as active ingredients, natural extracts having the effects of prevention, amelioration or treatment of acne by exhibiting high antibacterial activity against C. acnes, which is a strain causative of acne.
    Type: Grant
    Filed: March 10, 2021
    Date of Patent: October 26, 2021
    Assignee: CELIM BIOTECH CO.LTD
    Inventors: Jun Wan Kim, Yeong Cheol Park, Kyung Ho Lee, Hyungwoo Kim
  • Patent number: 11141485
    Abstract: A valerian composition includes a therapeutically effective pharmaceutical dosage form having a solid core including a polymer in which valerian and a valerian stability improving amount of an acidifying agent are contained. The valerian stability improving amount of acidifying agent being sufficient to impart a pH of 2 to 5 to the polymer.
    Type: Grant
    Filed: July 9, 2019
    Date of Patent: October 12, 2021
    Assignee: Société des Produits Nestlé S.A.
    Inventors: Syed M. Shah, Christopher Diorio, Daniel Hassan, Fred Hassan
  • Patent number: 11141484
    Abstract: A valerian composition includes a therapeutically effective pharmaceutical dosage form having a solid core including a polymer in which valerian and a valerian stability improving amount of an acidifying agent are contained. The valerian stability improving amount of acidifying agent being sufficient to impart a pH of 2 to 5 to the polymer.
    Type: Grant
    Filed: July 3, 2019
    Date of Patent: October 12, 2021
    Assignee: Société des Produits Nestlé S.A.
    Inventors: Syed M. Shah, Christopher Diorio, Daniel Hassan, Fred Hassan
  • Patent number: 11135256
    Abstract: A pharmaceutical composition for ischemia treatment of a patient includes a ginkgo extraction and a pharmaceutically acceptable carrier. The dosage form of the pharmaceutical composition is gel, transdermal patch, cream or paste. The patient is a neonate, an infant, or an early child. A use of the pharmaceutical composition for ischemia treatment of a patient is disclosed.
    Type: Grant
    Filed: November 29, 2019
    Date of Patent: October 5, 2021
    Assignee: SHIN-KONG WU HO-SU MEMORIAL HOSPITAL
    Inventor: Shu-Chi Mu
  • Patent number: 11129864
    Abstract: The invention relates to a tablet or capsule containing a plant extract, to assist in the treatment or prevention of disorders or diseases. The tablet or capsule includes bioconverted products provided by fermenting Withania Somnifera extract, Emblica officinalis extract, and Bacopa monnieri extract.
    Type: Grant
    Filed: May 21, 2018
    Date of Patent: September 28, 2021
    Assignees: Ethnodyne, Centre National de la Recherche Scientifique (CNRS)
    Inventors: Chérif Rabhi, Léon Cariel, Jamal Ouazzani, Guillaume Arcile
  • Patent number: 11123393
    Abstract: The present disclosure provides mixtures of prenylated flavonoids, stilbenes, or both with flavans or curcuminoids or both capable of modulating joint inflammation, joint pain, joint stiffness, cartilage degradation, or improving mobility, range of motion, flexibility, joint physical function, or any combination thereof. Such a mixture of prenylated flavonoids, stilbenes, or both with flavans or curcuminoids or both can optionally be used in combination with other joint management agents, such as non-steroidal anti-inflammatory agents/analgesics, COX/LOX inhibiting agents, glucosamine compounds, neuropathic pain relief agents, or the like.
    Type: Grant
    Filed: June 16, 2014
    Date of Patent: September 21, 2021
    Assignee: Unigen, Inc.
    Inventors: Lidia Alfaro Brownell, Min Chu, Mei-Feng Hong, Eu-Jin Hyun, Qi Jia, Ping Jiao, Hyun-Jin Kim, Mi-Ran Kim, Tae-Woo Kim, Bo-Su Lee, Young-Chul Lee, Breanna Moore, Jeong-Bum Nam, Mi-Sun Oh, Mi-Hye Park, Mesfin Yimam, Qian Zhang
  • Patent number: 11123396
    Abstract: The present disclosure discloses a herbal formulation in powdered dosage form, which is useful to enhance the physical endurance or strength in athletes. The disclosure also includes a method of preparation of the formulation, which involves the encapsulation of the natural ingredients in a natural matrix. The formulation comprises Moringa oleifera, Kaempferia parviflora and Punica granatum that are processed to obtain the product in powder form by encapsulation of the natural ingredients in a natural matrix. The formulation increased the nitrate and nitrite levels in serum and saliva in human and is useful to improve the general health of the athletes.
    Type: Grant
    Filed: August 19, 2017
    Date of Patent: September 21, 2021
    Assignee: Aurea Biolabs Private Limited
    Inventors: Sreeraj Gopi, Karthik Varma Ayiranazhi Covilakam, Joby Jacob
  • Patent number: 11116780
    Abstract: Provided herein is a topical analgesic composition that includes an external analgesic agent, one or more pharmaceutically acceptable excipients, and at least one of a cannabinoid, terpene, and flavonoid. Also provided is a method that includes topically administering to a skin surface of a subject (e.g., human) the topical analgesic composition.
    Type: Grant
    Filed: July 14, 2020
    Date of Patent: September 14, 2021
    Inventors: Tony LaRosa, Robert Davidson, David Reid
  • Patent number: 11110372
    Abstract: The invention relates to methods of producing extracts from cannabis plant material, where the extracts comprise cannabinoids and terpenes. The methods comprise extracting fresh or dried plant material with a cold organic solvent. The methods allow for the extraction of cannabinoids and terpenes, while leaving behind impurities such as waxes and chlorophyll that are commonly found in extractions with room temperature (RT) or warm solvent extraction methods. The methods can produce extracts having more than 90% cannabinoids.
    Type: Grant
    Filed: August 21, 2020
    Date of Patent: September 7, 2021
    Assignee: Neptune Wellness Solutions Inc.
    Inventors: Fereshteh Farokhi, Pierre St-Jean, Etienne Villeneuve
  • Patent number: 11110143
    Abstract: The present disclosure discloses a method for preparing a citrus-derived complex prebiotic agent. The method comprises the following steps: removing external citrus peels after blanching citrus fruits with hot water, soaking citrus segments after splitting with an acid solution and an alkali solution to remove membranes of the citrus segments, and adjusting the pH of the obtained alkali soaking water with acid soaking water or acid to be weakly acidic or neutral to obtain the complex prebiotic agent, which has the function of reversing intestinal flora disorders. Compared with the traditional prebiotic product preparing method, the product prepared by the method contains prebiotic functional components with different targets such as pectin, flavonoids, oligosaccharides, and other fibers at the same time, and has the efficacies of regulating intestinal flora and reversing intestinal flora disorders caused by antibiotics.
    Type: Grant
    Filed: September 27, 2018
    Date of Patent: September 7, 2021
    Assignee: ZHEJIANG UNIVERSITY
    Inventors: Shiguo Chen, Jiaqi Zheng, Xingqian Ye, Donghong Liu, Hua Zhang
  • Patent number: RE49035
    Abstract: A traditional Chinese medicine composition for treating cardiovascular disease, and a preparation thereof, particularly a micro drop pill preparation thereof, and a method for preparing the preparation; the method for preparing the micro drop pill preparation can be used to prepare drop pills, coated drop pills, and drop pill capsules with a high drug loading capacity.
    Type: Grant
    Filed: December 16, 2019
    Date of Patent: April 19, 2022
    Assignee: Tasly Pharmaceutical Group Co., Ltd.
    Inventors: Xijun Yan, Naifeng Wu, Kaijing Yan, Zhengliang Ye, Shunnan Zhang, Lihong Zhou, Wensheng Zhang, Hai'ou Dong
  • Patent number: RE49050
    Abstract: A traditional Chinese medicine composition for treating cardiovascular disease, and a preparation thereof, particularly a micro drop pill preparation thereof, and a method for preparing the preparation; the method for preparing the micro drop pill preparation can be used to prepare drop pills, coated drop pills, and drop pill capsules with a high drug loading capacity.
    Type: Grant
    Filed: December 13, 2019
    Date of Patent: April 26, 2022
    Assignee: Tasly Pharmaceutical Group Co., Ltd.
    Inventors: Xijun Yan, Naifeng Wu, Kaijing Yan, Zhengliang Ye, Shunnan Zhang, Lihong Zhou, Wensheng Zhang, Hai'ou Dong, Yongfeng Zheng, Lijun Fan