Abstract: A use of Magnolia figo extract in the manufacture of a compound for reducing epidermal desquamation and promoting wound healing.

Abstract: The present disclosure provides compositions as topical creams for treating vaginal atrophy, methods of making these compositions, and methods of using these compositions to treat vaginal atrophy.

Abstract: The present disclosure relates to compounds that bind to at least one of ACAT1/2 and OXCT1/2 and inhibit mitochondrial ATP production, referred to herein as mitoketoscins. Methods of screening compounds for mitochondrial inhibition and anti-cancer properties are disclosed. Also described are methods of using mitoketoscins to prevent or treat cancer, bacterial infections, and pathogenic yeast, as well as methods of using mitoketoscins to provide anti-aging benefits. Specific mitoketoscin compounds are also disclosed.

Abstract: Provided are methods for selective extraction of cannabinoids, for example cannabidiol (CBD), from a plant source, by using tailored extraction media.

Abstract: The present disclosure relates to compounds that bind to at least one of ACAT1/2 and OXCT1/2 and inhibit mitochondrial ATP production, referred to herein as mitoketoscins. Methods of screening compounds for mitochondrial inhibition and anti-cancer properties are disclosed. Also described are methods of using mitoketoscins to prevent or treat cancer, bacterial infections, and pathogenic yeast, as well as methods of using mitoketoscins to provide anti-aging benefits. Specific mitoketoscin compounds are also disclosed.

Abstract: A novel oleogel is provided comprising an edible oil in an amount of at least 95 wt % combined with a binary wax blend in an amount of less than 5 wt % of the oleogel, wherein the oleogel exhibits less than 10% oiling off and a back-extrusion hardness of greater than 100 g-force. The edible oil may be a high oleic acid-containing oil, such as a vegetable oil having a total monounsaturated fatty acid content of at least about 25% by wt. The binary wax blend may comprise at least two waxes selected from rice bran wax, carnauba wax, candelilla wax, sunflower wax, jojoba oil wax, corn oil wax, sugarcane wax, ouricury wax, beeswax and retamo wax. The oleogel provides an edible fat substitute prepared from oil having a reduced saturated fatty acid and trans fatty acid content that may be incorporated in a variety of food products.

Abstract: The invention relates to compositions comprising complexes of ?-cyclodextrin and cannabinoids and/or complexes of ?-cyclodextrin and terpenes, methods of making these ?-cyclodextrin and cannabinoid complex-containing compositions, and methods of using the ?-cyclodextrin and cannabinoid complex-containing compositions. The invention also relates to food products comprising the ?-cyclodextrin and cannabinoid complex-containing compositions of this invention.

Abstract: An object of the present invention is to provide a novel composition that is, for example, effective in suppression of deterioration of mental function. The present invention provides a composition for use in suppressing deterioration of mental function, comprising a hop oxidation-reaction product. Conditions of deterioration of mental function include conditions selected from the group consisting of depression-related conditions and anxiety-related conditions. The composition of the present invention can be provided in the form of a food composition, and be ingested by subjects with deterioration of mental function or with a risk of deterioration of mental function. The S-fraction can be used as the hop oxidation-reaction product.

Abstract: The present disclosure encompasses compositions prepared from Boysenberry and apple, as well as compositions prepared from Boysenberry, apple and blackcurrant. Also encompassed are methods of preparing these compositions and methods of using these compositions, in particular, for treating or preventing disorders of the respiratory system, including amongst others: inflammation, asthma, chronic obstructive pulmonary disease, allergic airways inflammation, reactive airway disease, airway fibrosis, and airway remodelling.

Abstract: A method of processing cannabis plant matter is provided. It is a particular aspect of the invention to utilize cannabis waste from the processing methods and in a sense recycle and use the byproducts to create additional products. The method describes harvesting cannabis plant matter at a predetermined time, processing the cannabis plant matter to create cannabis juice and cannabis pulp, and utilizing the cannabis pulp to create additional products. This eliminates the waste from processing cannabis plant matter solving a potential crisis in the fact that cannabis plant matter having cannabinoids leech into the soil and water table from disposal.

Abstract: Disclosed are a Piper laetispicum extract and a preparation method therefor and a use thereof. The Piper laetispicum extract includes any one or more of sesamin, (2E,6E)-N-isobutyl-7-(3,4-methylenedioxyphenyl)heptadienamide, (2E,4E)-N-isobutyldodecane-2,4-dieneamide, (2E,4E)-N-isobutyl-15-phenylpentadeca-2,4-dieneamide, (2E,4E,14Z)—N-isobutyleicosane-2,4,14-trienamide, and (2E,4E)-N-isobutyl-13-phenyltrideca-2,4-dieneamide. The Piper laetispicum extract can prevent depression.

Abstract: An oriental shampoo composition that can help maintain the health of the scalp and hair and help alleviate hair loss is provided. The shampoo composition includes, among others, 47.89% by weight of purified water; 10.00% by weight of a herbal mixed solution containing purified water, Rehmannia chinensis root extract, butylene glycol, Mentha arvensis extract, 1,2-hexanediol, Acorus gramineus root extract, Biota orientalis leaf extract, Chrysanthemum zawadskii extract, Panax ginseng root extract, Glycyrrhiza galbra (licorice) root extract, Lycinum chinense fruit extract, Morus alba bark extract, Xanthium strumarium fruit extract, and ethyl hexyl glycerin; 10.00% by weight of a mixed solution containing sodium lauryl sulfate, purified water, disodium phosphate and sodium carbonate; 10.00% by weight of a mixed solution containing purified water, TEA-lauryl sulfate and sodium benzoate; and 8.0% by weight of a mixed solution containing purified water, cocamidopropyl betaine and sodium chloride.

Abstract: In an LC system using an ODS column (15) and UV detector (17), a cannabis-derived sample is analyzed by gradient elution using a phosphoric acid aqueous solution and phosphoric-acid-containing methanol. A control unit (3) regulates the openings of solenoid valves in a mixer (12) so that the increase rate of the mixture ratio of the phosphoric-acid-containing methanol in a second part of the analysis period is higher than in a first part. By this operation, ten active ingredients (including Total THC, Total CBD and CBN) contained in cannabis can be satisfactorily separated within an analysis time which is equal to or even shorter than approximately 30 minutes. Each ingredient separated by the column (15) is detected by the UV detector (17). An active ingredient identification processor (22) identifies the ten active ingredients based on the retention times of the peaks on a chromatogram created from the detection signals.

Abstract: A method of isomerizing ?9-tetrahydrocannabinol (“?9-THC”) to ?10-tetrahydrocannabinol (“?10-THC”). The method includes the steps of: extracting ?9-THC from cannabis biomass, which optionally contains one or more of the components found in fire retardant such as PHOS-CHEK®; dewaxing of crude extracts by winterization; pH-adjusting extracts by washing the extracts in heptane solution with aqueous solutions of: citric acid, sodium bicarbonate, and brine; isomerizing ?9-THC to ?10-THC by exposure to suitable conditions and in the presence of a catalyst based on the components of fire retardant; vacuum distillation of ?10-THC at a predetermined temperature range and vacuum level; collecting the distillate and redistilling it up to three times to acquire distillate containing less than 60% ?10-THC; and purification of the MO-THC to a purity of 99% or greater by crystallization from n-pentane solution.

Abstract: A composition for preventing or treating hearing loss, containing a Vitis vinifera leaf extract as an active ingredient, is disclosed. A pharmaceutical composition for preventing or treating hearing loss, containing the extract (a Vitis vinifera leaf extract) as an active ingredient, protects auditory hair cells in the cochlea and spiral ganglion cells from damage caused by noise and the like and effectively reduces the hearing threshold measured in the auditory nerves, thereby being usable as an agent for preventing or treating hearing loss.

Abstract: Methods for the production of different cannabis product compositions. Method for the production of at least two different cannabis product compositions from a solid cannabis plant material are described including providing a solid cannabis plant material containing at least one cannabinoid and at least one terpene at cannabinoid to terpene weight/weight ratio R100; first extracting from said solid cannabis plant material a first composition comprising at least 10% but less than 90% of said cannabinoid and at least 1% of said terpene at cannabinoid to terpene weight/weight ratio R101, wherein R101 differs from R100 by at least 10%; second extracting from said solid cannabis plant material a second composition comprising at least 10% of said cannabinoid and at least 1% of said terpene at cannabinoid to terpene weight/weight ratio R102, wherein R102 differs from R101 by at least 10%; and optionally refining said first composition, said second composition, or both.

Abstract: The present invention refers to dermocosmetic formulations for use against skin blemishes, especially melasma. The present invention minimizes or avoids the formation of melasma by acting in several stages of melanogenesis. A preferred embodiment of the invention refers to dermocosmetic formulations that act in several stages of melanogenesis, preferably, in the gene expression of tyrosinase-related proteins (TYRP-1 and TYRP-2) and Endothelin-1 (ET-1). Another embodiment of the invention refers to the cosmetic composition containing a combination of active ingredients that act on the gene expression of tyrosinase-related proteins (TYRP-1 and TYRP-2) and Endothelin-1 (ET-1). In another preferred embodiment of the invention, the use of said cosmetic composition to combat melasma is described.

Abstract: The invention provides an extract of Plectranthus amboinicus (Lour.) Spreng enriching anti-arthritis activity, which is obtained by eluting the crude extract of Plectranthus amboinicus (Lour.) Spreng using 50%˜95% alcoholic solution or solvents such as hexane and/or ethyl acetate. Also provided is a method for treating arthritis comprising such extract.

Abstract: The present invention relates to novel compounds capable of activating BKCa channels. The use of a composition of the present invention can effectively activate the BKCa channels, and can be used for prevention or treatment of various diseases caused by the deactivation of BKCa channels or the degradation of BKCa channel activity.

Abstract: The present disclosure relates to a composition for ameliorating a circulatory system disease, which contains a green tea extract with modified ingredient content. According to the present disclosure, it is possible to effectively prevent, ameliorate and treat circulatory system diseases without side effects and, thereby, to greatly help patients with circulatory system diseases and contribute to the development of related industries.

Abstract: A system of monitoring depression in a user, uses a computer system. The system initially calibrates, to determine baseline information about the user for each of a plurality of different categories of action of the user and continues learning about the user to make minor adjustments to prescribed behaviors and therapies. The categories can include sleep, diet, screen time, exercise, social interaction, medication compliance, and academic performance. The computer system uses the baseline information to determine user behavior, for each of the different categories that is correlated with likely behavior associated with depression. After initially calibrating, the computer system operates to monitor each of said different categories of action of the user and compares the monitored categories with the baseline information to determine whether the user is complying by acting within specified parameters within each category. The system can provide positive reinforcement and alerts.

Abstract: The present invention relates to a pharmaceutical composition for use in the treatment of prostate pathologies. The present invention further relates to a composition comprising a mixture which comprises or, alternatively, consists of an effective amount of Serenoa repens, Bromelain, Curcumin, Zinc, Lycopene and Selenium, and pharmaceutically acceptable or food grade technological excipients and/or additives. The present invention further relates to a pharmaceutical composition, preferably in the form of softgel capsules, for use in the treatment of disorders or diseases or pathologies connected to and/or deriving from prostatitis and/or benign prostatic hyperplasia.

Abstract: Compositions and methods are presented that substantially increase levels of BDNF in blood, and even more pronouncedly exosomal BDNF levels. Suitable compositions include whole coffee fruit extracts and powders that are orally administered at relatively low dosages.

Abstract: The present invention about using chemicals to interfere with the ability of certain arthropods to shield themselves from their external environment. It teaches to apply chemicals to a specialized portions of the arthropod's body that maintain a gaseous envelope that encoats, protects and extends from the arthropod's skin and, if present, breathing hole. This chemical application causes a failure of this protective envelope, making the arthropod vulnerable its external environment such as to pesticides and can also lead to problems with its ability to breathe.

Abstract: An antioxidant dietary supplement composition comprises from 37 to 42% by weight of grapeseed extract, from 32 to 37% by weight of green tea extract, from 7 to 15% by weight of pine bark extract and from 7 to 15% by weight of pomegranate extract, wherein the % by weight is based on the total weight of the grapeseed extract, green tea extract, pine bark extract and pomegranate extract in the composition. The composition has use in the treatment of viral infections, especially respiratory infections, in mammals and birds, especially in humans, horses and camels. Also disclosed is a method of treating a viral infection in a mammal or bird which comprises administering to the mammal or bird a composition according to the invention.

Abstract: Provided are a method of preparing a cannabis processed product having an increased CBD content in an efficient and economic manner, through decarboxylic acid reaction by microwave irradiation of cannabis using various extraction solvents, and use of the processed product having an increased CBD content prepared by the method, a fraction thereof, and a single ingredient of CBD, in foods, drugs, and cosmetics.

Abstract: The present invention relates to a composition for antioxidation, anti-inflammation, or osteoclast differentiation inhibition and a composition for arthritis treatment, each of the compositions containing a fraction of a complex extract of Cynanchum wilfordii, Phlomis umbrosa, and Angelica gigas as an active ingredient. The compositions of the present invention can be effectively used for osteoclast differentiation inhibition, antioxidation, or anti-inflammation, and arthritis treatment.

Abstract: The present invention relates to a composition and method for improving the quantity of tear fluid, a composition and method for treating constipation, and a composition and method for improving skin quality. By utilizing an extract of Black ginger (Kaempferia parviflora)), the quantity of tear fluid, constipation, and skin quality are improved.

Abstract: Embodiments of the invention involve treating ophthalmology conditions by the topical or oral use of acetylcholinesterase inhibitors. By effectively reducing or eliminating the population of Demodex mites in affected areas and areas where Demodex mites may exist, this treatment achieves a more complete remission of clinical signs and symptoms of the ophthalmological afflictions than any previously described method. Embodiments of the invention are useful for treating ocular afflictions caused by Demodex-induced inflammatory eye conditions, including meibomian gland dysfunction, conjunctivitis, keratoconjunctivitis, hyperemia, blepharitis and dry eye disease.

Abstract: Provided are a composition for preventing or improving inflammation, the composition including an extract of a seed of soybean Glycine max (L.) Merrill cultivar SCEL-1, and a method of preventing occurrence of inflammation in a subject or improving inflammation in a subject, the method including injecting the composition to a subject.

Abstract: The invention relates to a personal care composition, more particularly to a composition for application to a topical surface that prevents or reduces inflammation. The composition could be delivered in the form of a skin, scalp, hair or oral care product, more particularly a skin care product. The benefit is delivered via a combination of a polyunsaturated fatty acid (PUFA) or ester thereof selected from docosahexaenoic acid (DHA), eicosapentaenoic acid (EPA), DHA-ethyl ester, EPA-ethyl ester, DHA-triglyceride, EPA-triglyceride, dihomogamma-Linolenic Acid (DGLA), DGLA-ethyl ester, DGLA-triglyceride or combinations thereof and a 4-substituted resorcinol compound, wherein the mole ratio of the PUFA or ester thereof to the 4-substituted resorcinol compound is 5:1 to 1:5.

Abstract: Compositions and methods for treating a disease are described herein. Compositions having plant preparations, microRNAs, and one or more rate limiters are administered to a patient to promote DNA damage repair and modulate endothelial and mitochondrial function, thereby allowing for healing to occur.

Abstract: An extract of Amaranth, having enriched nitrate content, L-arginine, Flavonoids, saponins, alkaloids, carbohydrates, proteins, potassium, and with negligible amount of oxalic acid or oxalate content. The extract of Amaranth can be prepared from fresh or dried leaves and stem of Amaranth. Dosage forms of extract include fast melt tablet, lozenge, candy, chewing gum, beverage, tablet, capsule, pill, and powder. The extract of Amaranth enhances nitric oxide concentration, enhances nitrate level concentration, and enhances nitrite level in blood as well as in saliva. Administering the extract can lower blood pressure, increase physical endurance, increase swimming endurance, increase running endurance, and improve sexual performance among human beings.

Abstract: Embodiments of the disclosure provide a method of managing information related to a cannabis product across a distributed validated system. The method includes enabling an authorized user to create a plurality of data containing genetic profile of a seed, plant growth conditions of a crop, and manufacturing information used for production of the cannabis product, and measurements of quality and quantity of desired components and undesired components in the cannabis product. The method includes associating the plurality of data to a record which is identified by a unique identifier. The method includes storing the record into a memory for access by one or more of a plurality of authorized users using the unique identifier. The method includes analyzing the cannabis product to determine the quality and quantity of desired components and undesired components in the cannabis product. The method includes determining concentration of cannabinoids in the cannabis product.

Abstract: Disclosed is a method of applying a topical skin composition to skin. The method can include applying the composition to skin. The composition can include Silybum marianum fruit extract and Momordica grosvenorii fruit extract.

Abstract: The invention provides various novel compositions of berberine in combination with pharmacologically active EPA and DHA, and related methods of their use in treating various diseases or disorders. The pharmaceutical compositions of the invention are useful in treating and/or preventing various diseases or disorders, including metabolic diseases or disorders such as dyslipidemia, hyperglycemia, hypertriglyceridemia, hyperlipidemia, diabetic dyslipidemia, diabetic hyperlipidemia, dyslipidemia in statin-intolerance patients, diabetes, diabetic complications, hypercholesterolemia, or obesity. Additionally, the pharmaceutical compositions of the invention are useful in treating and/or preventing atherosclerosis, heart diseases, neurodegenerative diseases, inflammation, cancers, as well as various liver diseases or disorders, such as fatty liver, non-alcoholic fatty liver disease, non-alcoholic steatohepatitis, cholestatic liver diseases or graft-versus-host disease of the liver.

Abstract: The present invention relates to an apparatus for plant management. It is described to provide (210) a processing unit with at least one image of a field. The processing unit analyses (220) the at least one image to determine information relating to a plant that is present. The processing unit determines (230) if the plant is to be controlled or is not to be controlled by a plant control technology based on the information relating to the plant. An output unit outputs (240) information that is useable to activate at least one plant control technology if the determination is made that the plant is to be controlled by the plant control technology.

Abstract: The present invention relates to an apparatus that provides therapeutic effects and a source of hydration. The apparatus includes a garment that has one or more compartments for storing a therapeutic element. The therapeutic element may include one or more herbs, essential oils, and combinations thereof. The apparatus also includes a portable drinking apparatus attached to the garment. The portable drinking apparatus includes a pouch having a liquid reservoir inserted therein and a drinking tube having a first end in fluid communication with the liquid reservoir and a second end having a mouth operated valve. Methods of use are also disclosed.

Abstract: The invention relates to an in vitro method for evaluating digestive efficiency (DE) of poultry, in particular chickens, by measuring color of a sample of liquid fraction of blood of said poultry.

Abstract: Embodiments of the invention are directed to compositions containing cannabinoid, cannabidiol, or cannabidiol analog for lightening or whitening skin, and methods for lightening skin tone or whitening skin by administering compositions containing cannabinoid, cannabidiol, or cannabidiol analog to the skin.

Abstract: A method of treating a malignant disease in a subject in need thereof is provided. The method comprising administering to the subject a therapeutically effective amount of a first liquid chromatography fraction of a cannabis extract comprising at least 75% tetrahydrocannabinolic acid (THCA), and a therapeutically effective amount of a second liquid chromatography fraction of a cannabis extract comprising at least 75% cannabigerolic acid (CBGA), wherein the first liquid chromatography fraction comprises cannabis derived active ingredients other than the THCA, and the second liquid chromatography fraction comprises cannabis derived active ingredients other than the CBGA, thereby treating the malignant disease in the subject.

Abstract: The purpose of the present invention is to provide a substance related to the stabilization of capillary blood vessels. This invention is based on the discovery that an extract from a plant selected from the group consisting of Calendula officinalis, Siberian ginseng, and Cistanche salsa increases gene expression of VE-cadherin or integrin ?5.

Abstract: Disclosed is a combination of extracts of Cynara cardunculus and Citrus bergamia which are useful for the prevention and treatment of hepatic steatosis and other disorders correlated with dyslipidaemic conditions.

Abstract: The invention relates to a use of Copaifera oleoresin for producing a medicament for preventing and/or treating pathologies of the prostate, particularly benign prostatic hyperplasia and/or prostate cancer.

Abstract: Chromatography systems and methods for using carbon dioxide to separate one or more cannabis-derived compounds from other components of a mixture are generally described. Some of the methods described herein comprise transporting a mixture comprising a first cannabis-derived compound and one or more other components through a chromatography column containing a stationary phase comprising a packing material. In some embodiments, the mixture is transported through the column within a mobile phase that comprises carbon dioxide (e.g., supercritical CO2, liquid CO2). The mobile phase may be substantially free of a co-solvent that is in liquid phase at standard room temperature and pressure. In some embodiments, the mobile phase is free of any co-solvent and comprises 100 vol % carbon dioxide.

Abstract: A cosmetic concentrate base composition and cosmetic compositions for use as creams or lotions utilizing the same, the cosmetic concentrate base composition including approximately 20% to 25% by weight of a first component, the first component being a phospholipid component; approximately 10% to 40% by weight of a second component, the second component being a lipid component; and approximately 4% to 5% by weight of a third component, the third component being a hydrophilic component.

Abstract: A method for treating phytophotodermatitis including the steps of applying an isothiocyanate functional surfactant to an area affected by phytophotodermatitis, wherein said isothiocyanate functional surfactant comprises at least one isothiocyanate functional group associated with an aliphatic and/or aromatic carbon atom of the isothiocyanate functional surfactant.

Abstract: Human therapeutic treatment compositions comprise at least two of a curcumin component, a harmine component, and an isovanillin component, and preferably all three in combination. The agents are effective for the treatment of human conditions, especially human cancers.

Abstract: A traditional Chinese medicine composition for treating cardiovascular disease, and a preparation thereof, particularly a micro drop pill preparation thereof, and a method for preparing the preparation; the method for preparing the micro drop pill preparation can be used to prepare drop pills, coated drop pills, and drop pill capsules with a high drug loading capacity.

Abstract: A traditional Chinese medicine composition for treating cardiovascular disease, and a preparation thereof, particularly a micro drop pill preparation thereof, and a method for preparing the preparation; the method for preparing the micro drop pill preparation can be used to prepare drop pills, coated drop pills, and drop pill capsules with a high drug loading capacity.