Containing Or Obtained From Prunus (e.g., Prune, Cherry, Plum, Apricot, Peach, Almonds, Etc.) Patents (Class 424/735)
  • Patent number: 11903977
    Abstract: Disclosed is a topical anhydrous, homogenous pharmaceutical composition for treating skin disorder and wounds comprising cod liver oil, hempseed oil, monolaurin, medium chain triglycerides (“MCT”), free fatty acids, sea salt, and vegetable oil selected from the group consisting of red palm concentrate, coconut oil, and red palm oil and combination thereof and optionally fish collagen, ascorbyl palmitate, thickening agent, such as beeswax, red palm concentrate and cetyl ester.
    Type: Grant
    Filed: April 12, 2019
    Date of Patent: February 20, 2024
    Assignee: Omeza Holdings, Inc.
    Inventors: Griscom Bettle, III, John Harlin, Thomas Gardner
  • Patent number: 11890369
    Abstract: A method for treating skin of a person is disclosed. The method can include topically applying to the skin of the person a composition comprising an effective amount of an aqueous, alcoholic, or aqueous-alcoholic extract from Callicarpa macrophylla, wherein the composition reduces TNF-? activity in skin, increases antioxidant activity in the skin, and/or increases skin moisture content.
    Type: Grant
    Filed: March 12, 2021
    Date of Patent: February 6, 2024
    Assignee: MARY KAY INC.
    Inventors: Tiffany Florence, David Gan, Michelle Hines
  • Patent number: 11666525
    Abstract: A method for treating skin of a person is disclosed. The method can include topically applying to the skin of the person a composition comprising an effective amount of an aqueous, alcoholic, or aqueous-alcoholic extract from Sequoia sempervirens, Geranium oil, panthenol, citric acid, and glycerin, wherein the composition increases antioxidant activity in the skin and/or increases skin moisture content.
    Type: Grant
    Filed: February 26, 2021
    Date of Patent: June 6, 2023
    Assignee: MARY KAY INC.
    Inventors: Tiffany Florence, David Gan, Michelle Hines
  • Patent number: 11135293
    Abstract: A method of enhancing penetration of a topical composition of 5-aminolevulinic acid (ALA) into tissue for photodynamic therapy includes topically applying ALA to a treatment area to be treated with photodynamic therapy. The method further includes, after the ALA is applied to the treatment area, covering the treatment area with a low density polyethylene barrier. The treatment area is covered with the low density polyethylene barrier prior to light treatment to minimize transepidermal water loss from the treatment area.
    Type: Grant
    Filed: December 2, 2020
    Date of Patent: October 5, 2021
    Assignee: DUSA PHARMACEUTICALS, INC.
    Inventors: Scott Lundahl, Michael Guttadauro
  • Patent number: 11045538
    Abstract: The present invention provides a method for treatment of hyperglycemia, particularly type 2 diabetes with Staphylococcal enterotoxins (SE). Also provided are a composition for treatment of hyperglycemia, comprising Staphylococcal enterotoxins, and a use of Staphylococcal enterotoxins for treatment of hyperglycemia.
    Type: Grant
    Filed: October 23, 2019
    Date of Patent: June 29, 2021
    Inventor: Mei-Nan Tuan
  • Patent number: 10980856
    Abstract: A topical, non-prescription formulation of essential oils combined with skin permeation enhancers for the clinical treatment of plantar fasciitis in humans. The formulation may exclude black pepper essential oil. The present compositions and methods relate to a method for treating a disorder chosen from plantar fasciitis, bursitis, or arthritis in humans in a patient in need thereof, comprising administering to the patient compositions having a therapeutically effective amount of a combination of isoprenoidal essential oils, for example, Tea Tree Oil and Clove Bud Oil, in combination with a skin permeation enhancer, such as DMSO, the administration comprising contacting an affected area of skin of the patient with the composition.
    Type: Grant
    Filed: October 24, 2018
    Date of Patent: April 20, 2021
    Inventor: Briant Burke
  • Patent number: 10723751
    Abstract: Provided are cyanogenic compositions for treating diseases, such as infectious diseases.
    Type: Grant
    Filed: January 16, 2019
    Date of Patent: July 28, 2020
    Inventor: Laszlo Sichtnik
  • Patent number: 10548937
    Abstract: A pharmaceutical composition or dietary supplement with antagonist activity on the degradation and degeneration of cartilage tissue, anti-inflammatory and analgesic activity is described, which is effective in the treatment of arthropathies and osteoarthritis, comprising, as active ingredients, a combination of methylsulfonylmethane, unsaponifiables of avocado and/or soybean, and S-adenosyl-L-methionine.
    Type: Grant
    Filed: August 18, 2015
    Date of Patent: February 4, 2020
    Assignee: Kolinpharma S.p.A.
    Inventors: Domenico Bijno, Carmine Di Vincenzo, Emanuele Lusenti, Alberto Martina, Ritapaola Petrelli
  • Patent number: 10471009
    Abstract: The present invention provides a sugar-depleted fruit or vegetable juice product, wherein said juice product is a fruit or vegetable juice or juice-retaining fruit or vegetable derived matter, wherein said juice product contains at least about 5 g/l gluconic acid and said juice product contains any two or three, of (i) at least about 0.5 g/l Ca2+, (iii) at least about 1 g/l K+, and (iii) at least about 0.1 g/l Mg2+. Also provided are methods of producing the same and the use thereof to assist in maintaining the health and well-being of a subject and in the treatment and prevention of medical ailments, specifically those associated with the over-consumption of glucose and/or sucrose or inappropriate metabolism of glucose, e.g. metabolic syndrome, diabetes mellitus type II, obesity, dyslipidemia, insulin resistance, hypertension and liver steatosis.
    Type: Grant
    Filed: October 1, 2015
    Date of Patent: November 12, 2019
    Assignee: NOFIMA AS
    Inventors: Jurgen Schrezenmeir, Svein Halvor Knutsen, Simon Ballance
  • Patent number: 10238701
    Abstract: The invention provides a water extract of Yan-Sheng-Yin (YSY), a Chinese natural dietary supplement for treatment and/or prevention of hyperlipidemia, atherogenesis and obesity, comprised entirely of natural foods and a preparation comprising the same.
    Type: Grant
    Filed: October 14, 2016
    Date of Patent: March 26, 2019
    Assignee: Taipei Medical University
    Inventors: Chieh-Hsi Wu, Chun-Hsu Pan, Chi-Han Wu
  • Patent number: 10213470
    Abstract: The present invention relates to a method for treating spinocerebellar ataxias comprising administering a pharmaceutical composition comprising of therapeutically effective amounts of Paeonia lactiflora and Glycyrrhiza uralensis to a subject in need. The pharmaceutical composition reduces productions of reactive oxygen species and inflammatory factors to suppress polyglutamine aggregation.
    Type: Grant
    Filed: January 15, 2016
    Date of Patent: February 26, 2019
    Assignee: NATIONAL TAIWAN NORMAL UNIVERSITY
    Inventors: Guey-Jen Lee-Chen, Chiung-Mei Chen
  • Patent number: 10195244
    Abstract: The present invention relates to a novel use of an Anemarrhena asphodeloides Bunge extract, and the like, and a Rhizoma Coptidis extract, and the like, and specifically, provides a composition for preventing, relieving, or treating colitis, including, as active ingredients: one or more selected from the Anemarrhena asphodeloides Bunge extract, a C3 to C8-alcohol-soluble fraction of the Anemarrhena asphodeloides Bunge extract, mangiferin, a pharmaceutically acceptable salt of mangiferin, neomangiferin, or a pharmaceutically acceptable salt of neomangiferin; and one or more selected from a Rhizoma Coptidis extract and a C3 to C8-alcohol-soluble fraction of the Rhizoma Coptidis extract.
    Type: Grant
    Filed: February 17, 2014
    Date of Patent: February 5, 2019
    Assignee: UNIVERSITY-INDUSTRY COOPERATION GROUP OF KYUNG HEE UNIVERSITY
    Inventors: Dong Hyun Kim, Myung Joo Han
  • Patent number: 10183964
    Abstract: Provided are cyanogenic compositions for treating diseases, such as infectious diseases.
    Type: Grant
    Filed: September 11, 2015
    Date of Patent: January 22, 2019
    Inventor: Laszlo Sichtnik
  • Patent number: 10058503
    Abstract: This invention is a natural face cream/lotion that exploits the benefits of Dead Sea salt for helping moisturize the skin of a human face. The lotion consists of natural ingredients such as organic aloe vera juice, shea butter, preferably unrefined, emulsified wax, Dead Sea salt, hydrolyzed wheat protein, essential oils (particularly lavender, rosehip seed oil and carrot seed oil), apple cider vinegar, and xanthan gum. They are included with a preservative made from leuconostoc/radish root ferment filtrate and phenoxyethanol.
    Type: Grant
    Filed: February 9, 2018
    Date of Patent: August 28, 2018
    Inventor: Noha N. Hakim
  • Patent number: 9949920
    Abstract: This invention is a natural deodorant composition that exploits the benefits of Dead Sea salt by adding it to a base of organic aloe vera juice, organic coconut oil, sweet almond oil, olive oil, NF emulsified wax (vegetable based), potato starch, and apple cider vinegar. It also includes several 100% pure essential oils, and preservatives.
    Type: Grant
    Filed: May 19, 2016
    Date of Patent: April 24, 2018
    Inventor: Noha N. Hakim
  • Patent number: 9867802
    Abstract: The present invention provides a method of treatment of Scedosporium spp. infection in an animal comprising the step of administering to the infected animal an effective amount of a compound of formula I or a pharmaceutically-acceptable salt thereof.
    Type: Grant
    Filed: May 13, 2013
    Date of Patent: January 16, 2018
    Assignee: BIODIEM LIMITED
    Inventors: Julie Phillips, Tania Sorrell, Sharon Chen
  • Patent number: 9750781
    Abstract: The present invention includes compositions and methods for cleaning, treating, protection and resolution of decubitus ulcers comprising: a first composition comprising a wound cleaning solution comprising aloe vera gel comprising at least 5,000 MPS, a balanced salt solution; and a second composition comprising a wound healing gel comprising aloe vera gel comprising at least 10,000 MPS, a thickening agent, and one or more preservatives and, optionally, a third composition comprising a moisture barrier cream comprising a vegetable-based emulsifier, a cosmetic ester for dry skin that has low occlusivity, an ester-based emollient that is oxidation stable and has low occlusivity; a beeswax; a hydrogenated oil, glycerin, a buffering agent, aloe vera gel comprising at least 2,000 MPS and water.
    Type: Grant
    Filed: December 22, 2014
    Date of Patent: September 5, 2017
    Assignee: Aloe Bioscience, LLC
    Inventor: Ivan E. Danhof
  • Patent number: 9700507
    Abstract: This invention is a natural scalp lotion that exploits the benefits of Dead Sea salt by adding it to a base of organic aloe vera juice, organic coconut oil, castor oil, sweet almond oil, olive oil, NF emulsified wax (vegetable based), potato starch, and apple cider vinegar. It also includes several 100% pure essential oils/extracts, and preservatives.
    Type: Grant
    Filed: May 27, 2016
    Date of Patent: July 11, 2017
    Inventor: Noha N. Hakim
  • Patent number: 9669061
    Abstract: The invention belongs in the field of medicine and can be used in the treatment of chronic and asymptomatic trichomonas infections of the urogenital tract. The invention is consisted in development of new therapeutic substance of plant origin with minimal side effects for treatment of various forms of trichomonad infection. The new therapeutic substance, of plant origin, is an olive coloured paste. It is composed of a conifer green needle complex (CGNC) and has a coniferous smell and antiprotozoal activity against Trichomonas vaginalis (when tested in an in vitro model). At a concentration of 100 mg/ml CGNC has trichomonadocitic and trichomonadostatic properties. At 300 mg/ml it suppresses the growth of T. vaginalis and at 500 mg/ml it kills this organism.
    Type: Grant
    Filed: May 5, 2009
    Date of Patent: June 6, 2017
    Assignees: Viktor Ivanovich Roschin, Vagif Sultanovich Sultanov
    Inventors: Viktor Ivanovich Roschin, Vagif Sultanovich Sultanov, Anatolii Borisovich Zhebrun, Tamara Valentinovna Nikitina, Lidija Borisovna Kuliashova, Lludmila Aleksandrovna Berezina
  • Patent number: 9662360
    Abstract: An improved method (process) is provided to treat herpes, pseudomonas, staphylococcus (staph), and hepatitis and help treat or alleviate cold sores, rashes, skin conditions, or symptoms resulting from herpes, pseudomonas, staph, and hepatitis. The method uses a special medicinal composition which can be self-administered and maintained for a prescribed time. The attractive medicinal composition can comprise a quaternary ammonium salt surfactant, a skin protectant and an alcohol. The quaternary ammonium salt surfactant can comprise benzalkonium halide, preferably benzalkonium chloride. The skin protectant can comprise Allantoin. The alcohol can serve as a pain reliever and can comprise benzyl alcohol. The medicinal composition can also include other compounds, additives, herbal extracts and/or carriers.
    Type: Grant
    Filed: December 7, 2015
    Date of Patent: May 30, 2017
    Assignee: Meritus Corporation
    Inventor: Meryl J. Squires
  • Patent number: 9314495
    Abstract: An improved process for the extraction of pygeum from the plant of the family rosacaea, amygdales tribe, genus Prunus species domestica (Indian Prunus) and related species (as herein defined) comprising the steps of collecting the plant material i.e. stem cuttings/twigs, removing the leaves and drying till moisture content is about 10-15%, powdering the stem material, extracting with chlorinated organic solvents and water-alcohol mixture, in ratio of 1:4, filtering and drying the extract under vacuum at 30 degree Celsius to obtain a greenish mass with bitter almond smell, the mass being referred to as ‘pygeum’ wherein in the improved process, a ‘renewable plant source’ i.e. stem cuttings/twigs, are used for extraction of pygeum instead of a ‘non-renewable’ source such as bark of the tree. The pygeum obtained by the new process has a pharmacopeia profile similar to the product ‘pygeum’ obtained from a ‘non-renewable source’ i.e. bark of Pygeum africanum.
    Type: Grant
    Filed: July 19, 2012
    Date of Patent: April 19, 2016
    Inventors: Kiran Tewari, Ashok Sharma
  • Patent number: 9044502
    Abstract: This invention relates to a Chinese medicinal formulation for the treatment of inflammatory bowel diseases, and a method of preparation thereof. The formulation comprises herbal components selected from a group consisting of Radix Codonopsis (Dangshen), Rhizoma Atractylodis Macrocephalae (Bai Zhu), Sclerotium Poriae Cocos (Fu Ling), Rhizoma Zingiberis Officinalis (Gan Jiang), Radix Paeoniae Alba (Bai Shao) and Rhizoma Coptidis (Huanglian).
    Type: Grant
    Filed: September 18, 2013
    Date of Patent: June 2, 2015
    Assignee: Hong Kong Baptist University
    Inventors: Zhaoxiang Bian, Siu Wai Tsang, Siu Po Ip, Che Yuen Justin Wu, Aiping Lu, Albert Sun Chi Chan
  • Publication number: 20150132280
    Abstract: A human dietary supplement comprises theacrine and optionally other compounds that modulate the effects of theacrine. Uses for the theacrine-containing supplement include improvement of at least one of mood, energy, focus, concentration or sexual desire or a reduction of at least one of anxiety or fatigue.
    Type: Application
    Filed: November 12, 2014
    Publication date: May 14, 2015
    Applicant: ORTHO-NUTRA, LLC
    Inventors: Hector L Lopez, Shawn Wells, Tim N. Ziegenfuss
  • Patent number: 9023325
    Abstract: Disclosed are topical skin compositions and corresponding methods of their use that include an extract from Artabotrys hexapetalus, an extract from Sassafras tzumu, and an extract from Prunus salicina.
    Type: Grant
    Filed: November 5, 2013
    Date of Patent: May 5, 2015
    Assignee: Mary Kay Inc.
    Inventors: Tiffany Florence, David Gan, Michelle Hines
  • Publication number: 20150110904
    Abstract: The present invention relates to a topical composition and method of use, specifically an oil-in-water emulsion, comprised of sweet almond oil, lavender oil, rose oil, cinnamon bark oil, and coriander seed oil in a physiologically acceptable topical carrier. The composition is applied to a circumcised penis to enhance sensitivity, preferably twice daily for a time period of at least about two weeks. Thereafter a maintenance dose can be applied once a day to maintain a desired level of sensitivity.
    Type: Application
    Filed: March 15, 2013
    Publication date: April 23, 2015
    Inventors: Servet Buyuktimkin, Nadir Buyuktimkin, James L. Yeager, Albert Liu
  • Publication number: 20150086655
    Abstract: Embodiments of the invention relate to fortified food and dietary supplement products which may be administered to produce desirable physiological improvement. In particular, embodiments of the invention relates to the administration of products enhanced with plant products and iridoids. A study was performed to evaluate the iridoid content, as well as the in vitro and in vivo bioactivities, of a beverage containing noni fruit, Cornelian cherries, and olive leaf extract. The major iridoids present were identified as asperulosidic acid, deacetylasperulosidic acid, oleuropein, morroniside, loganic acid, and loganin In the 2,2-Diphenylpicrylhydrazyl (DPPH) radical scavenging assay, remarkably high in vitro antioxidant activity was observed, with an IC50 of 3.8 ?L/mL. In vivo bioactivities were evaluated in type 2 diabetic Sprague Dawley rats.
    Type: Application
    Filed: September 20, 2013
    Publication date: March 26, 2015
    Inventors: Brett Justin West, Claude Jarakae Jensen, Afa Kehaati Palu, Shixin Deng, Jeffery A. Wasden
  • Publication number: 20150044308
    Abstract: The present invention relates to a pharmaceutical composition for treating urinary incontinence and/or enuresis, which comprises at least 0.5-20 wt % of a mixture of flavonoids, 2-20 wt % of condensed tannins or proantocyanidins and 0.3-60 wt % of gamma aminobutyric acid (GABA), with respect to the total composition. Said composition additionally comprises at least 0% of a Humulus lupulus extract. The present invention also relates to the use of said composition for preparing a medicine for treating incontinence and/or enuresis, in particular enuresis in children, as well as in adults or the elderly who have urine leaks such as incontinence due to stress or urgency.
    Type: Application
    Filed: January 22, 2013
    Publication date: February 12, 2015
    Inventor: Juan Carlos Llobregat Agusti
  • Publication number: 20150004139
    Abstract: The present invention provides a composition and method useful for creating a class of compounds that provide an emollient effect to the skin. The base formulation includes mixtures of certain oils that have high concentrations of Linoleic Acid, an essential fatty acid. Other oils are chosen which have high concentrations of Gamma-Linolenic Acid, Ricinoleic Acid and Oleic Acid. We have found that the incorporation of dl-alpha-tocopheryl and dl-alpha-tocopherol (vitamin E) improves the formulation and provides an anti-oxidative effect which preserves the end product and provides for a longer shelf life. The method disclosed creates free fatty acids, utilizing base catalyzed trans-esterification, inter-esterification and intra-esterification. The final products are lipid compounds which aid in treating dry skin conditions caused by deficiencies in Linoleic Acid or other fatty acids.
    Type: Application
    Filed: June 16, 2014
    Publication date: January 1, 2015
    Inventors: Rodney David Lewis, Paige Mashara Lewis
  • Patent number: 8916161
    Abstract: The present invention provides a method of treating BPH using modified pore-forming proteins (MPPs). These MPPs are derived from naturally occurring cytotoxic proteins (nPPs) that kill cells by forming pores or channels in the cell membrane, resulting in cell death. The MPPs are generated by modification of the nPPs such that they are capable of being selectively activated at normal prostate cells. Such modification may include the addition of a prostate-specific protease cleavage site to the activation sequence, and/or the addition of a prostate-specific targeting domain to allow selective targeting of prostate cells. These MPPs are capable of selectively targeting and killing normal prostate cells in vivo. The MPPs may be used either alone or in combination with other therapies for the treatment of BPH.
    Type: Grant
    Filed: June 14, 2006
    Date of Patent: December 23, 2014
    Assignee: Sophiris Bio Inc.
    Inventor: James Thomas Buckley
  • Publication number: 20140356419
    Abstract: Described herein is a polyherbal composition effective in skin care, including singularly or in certain combinations 0.01% to 15% of Ziziphus extract, 0.01% to 10% of Prunus extract, suitable delivery system, and a suitable carrier.
    Type: Application
    Filed: January 7, 2013
    Publication date: December 4, 2014
    Applicant: Shiromani Gurudwara Prabandhak Committee's Guru Nanak Khalsa College
    Inventors: Sukhjeet Kaur Gujral, Ramesh Trimbak Sane
  • Publication number: 20140348873
    Abstract: Compositions and methods for urea silicone gels for treating hyperkeratotic skin diseases that may benefit from barrier protection and from urea silicone gel's ability to return water balance to the skin are disclosed. Skin conditions that may be treated with urea silicone gels may be excessive dryness, callus, corns, old and new scars, and keloids, among others. Disclosed urea silicone gels may include micronized urea USP, and an anhydrous silicone base, among other ingredients. Anhydrous silicone base may include Amazonian oils such as pracaxi oil and seje oil, which are rich in oleic, linolenic, linoleic acids, and sterols, particularly beta-sitosterol and stigmasterol, which may increase skin permeability to urea. Additionally, because of the high content of unsaturated fatty acids of pracaxi oil and seje oil, disclosed urea silicone gel may exhibit an enhanced hydrating effect on skin cells, over-moisturizing and hydrating tough, thick hyperkeratotic conditions.
    Type: Application
    Filed: May 22, 2013
    Publication date: November 27, 2014
    Applicant: PROFESSIONAL COMPOUNDING CENTERS OF AMERICA
    Inventor: Fabiana Campanati Banov
  • Patent number: 8895034
    Abstract: A topical skin care lotion includes materials for supplementing the production of collagen I and III includes a base of lipophillic or lipophobic material and at least one amino acid. The amino acids are alanine and glycine. Other components of the lotion include iron, vitamin C, manganese, silica and cherry fruit extract. Together, these components assist the body with the production of collagen and promote healing of damaged skin. Antioxidants are also provided to protect the skin from oxidative stress by ultraviolet sunlight and environmental hazards.
    Type: Grant
    Filed: November 2, 2011
    Date of Patent: November 25, 2014
    Inventor: Mark K. Bennett
  • Publication number: 20140335209
    Abstract: There is provided a process for making a composition suitable for topical application comprising the steps of a) heating at least one fruit and/or vegetable pulp to up to a temperature in the range of about 40° C. to 100° C.; b) mixing between 1 and 40% w/w of a mild base with the heated fruit and/or vegetable pulp. There is also provided a fruit and/or vegetable derived composition suitable for topical application prepared by the above process. There is further provided a fruit and/or vegetable derived composition comprising at least one fruit and/or vegetable-derived pulp and a mild base, said composition having a pH in the range of about 7.5 to about 9.5.
    Type: Application
    Filed: February 12, 2014
    Publication date: November 13, 2014
    Inventor: Thomas James MCARTHUR
  • Publication number: 20140308374
    Abstract: The present invention describes a formulation comprising a prune and/or plum concentrate, and one or more water-soluble, non-digestible, prebiotic oligosaccharides. Optionally, one or more low calorie sweeteners, an antioxidant, calcium sennosides, or sennosides extract, PEG-3350, licorice, cocoa, coffee, tea flavors; fruit flavorings and spice flavorings, gelatin, agar-agar, carrageenan, pectin or cocoa powder are added. Other ingredients may be present as dietary supplements such as water-soluble vitamins, lipid-soluble vitamins; amino acids, maltodextrin, resveratrol, caffeine, mineral supplements, or natural sleep aids for use as a laxative, A variety of formulations are possible, such as premix, a laxative+energy power drink or power bar, or as a prebiotic supplement in probiotic yogurts, or in the form of gummies, chocolates, candies, and desserts such as red beans Japanese desserts.
    Type: Application
    Filed: November 2, 2012
    Publication date: October 16, 2014
    Applicant: Jiva Pharma, Inc.
    Inventor: Om P Goel
  • Publication number: 20140234447
    Abstract: The present invention concerns a composition to be applied to the skin, which comprises a dermatologically compatible vehicle, coconut oil, hazelnut oil and/or avellana oil, and stinging nettle oil, as well as use thereof for the treatment of skin diseases.
    Type: Application
    Filed: September 10, 2012
    Publication date: August 21, 2014
    Inventor: Ali Nahavandi
  • Patent number: 8802165
    Abstract: The present disclosure concerns phenolic extracts containing procyanidins, propelargonidins and prodelfinidins obtained from peel of the almond [Prunus dulcís (Mili.) D. A. Webb, Prunus amygdalus (L.) Batsch., Amygdalus dulcís (Mili.), Amygdalus communis (L.) or Prunus communis (L.)]. In particular, the objective is to obtain extracts rich in proanthocyanidins with type-A bonds. The preparation method disclosed comprises: (a) a maceration of plant material with organic solvents at 25-100° C., (b) purification by liquid-liquid extraction and/or adsorption or ion exchange chromatography, and (c) optionally, a final drying. Also disclosed are the possible activities/properties of these extracts such as anti-oxidant activity and others, which determine the use thereof as a nutritional or health ingredient, and the use thereof in the cosmetic and pharmaceutical industry.
    Type: Grant
    Filed: May 28, 2008
    Date of Patent: August 12, 2014
    Assignees: Consejo Superior de Investigaciones Cientificas, Biosearch, S.A.
    Inventors: Begoña Bartolomé´Sualdea, María Monagas Juan, Ignacio Garrido Lafuente, María Carmen Gómez-Cordovés De La Vega, Rosa Lebrón Aguilar, José Carlos Quintela Fernandez, Esther De La Fuente García, Alejandro Jara García-Navas
  • Publication number: 20140205550
    Abstract: A method of cosmetic care comprising activating capsase-14 expression in skin deficient in caspase-14 expression by applying, on at least one skin zone in need thereof, an effective amount of a plant extract selected from the group consisting of litchi, glasswort, peach, soja seed, sweet basil, cucumber, chanterelle, leek, kiwi fruit, rhubarb, grapefruit, wheat, raspberry, plum, and mixtures thereof, to activate caspase-14 expression in said skin.
    Type: Application
    Filed: January 23, 2013
    Publication date: July 24, 2014
    Inventors: Hugo A. Corstjens, Lieve Declercq, Gerry Eyckmans, Luc F.J. Van Overloop
  • Publication number: 20140161903
    Abstract: The invention features topical formulations comprising an osmotically active agent and/or a vasoconstrictor and/or an astringent agent for the treatment and prevention of eyelid swelling, and methods of use thereof.
    Type: Application
    Filed: February 12, 2014
    Publication date: June 12, 2014
    Applicant: ACIEX THERAPEUTICS, INC.
    Inventors: Matthew J. Chapin, Mark Barry Abelson, Keith Jeffrey Lane, Akimitsu Makino
  • Publication number: 20140161912
    Abstract: Methods and compositions using an orthosilicate for tissue regeneration, such as to treat a disease or condition, are described, including on the skin. Also described are methods for making such compositions.
    Type: Application
    Filed: December 11, 2013
    Publication date: June 12, 2014
    Applicant: ORBIS HEALTH SOLUTIONS, LLC
    Inventor: Thomas E. WAGNER
  • Patent number: 8679553
    Abstract: An herbal composition for providing a beneficial effect to the respiratory tract. The composition includes Thyme Leaf, Wild Cherry Bark, Cocoa Extract, Mullein Leaf Extract, and Boswellia Serrata. In particular, the composition may prevent or treat cough, specifically caused by exposure to smoke. Also described are methods of using the herbal composition.
    Type: Grant
    Filed: December 26, 2012
    Date of Patent: March 25, 2014
    Assignee: Aadvantics Pharmaceuticals, Inc.
    Inventors: Brian M. Levine, William E. Berger
  • Patent number: 8668944
    Abstract: A method for making and applying a topical oil and composition thereof, combining the healing properties of the Noni plant with a topical application for treating physical ailments. The topical oil disclosed includes an oil derived from raw leaves, stems, and buds of a noni plant; a carrier oil; and vitamin E oil.
    Type: Grant
    Filed: April 3, 2007
    Date of Patent: March 11, 2014
    Inventor: Donna Greco
  • Publication number: 20140065083
    Abstract: Disclosed are topical skin compositions and corresponding methods of their use that include an extract from Artabotrys hexapetalus, an extract from Sassafras tzumu, and an extract from Prunus salicina.
    Type: Application
    Filed: November 5, 2013
    Publication date: March 6, 2014
    Applicant: MARY KAY, INC.
    Inventors: Tiffany Florence, David Gan, Michelle Hines
  • Publication number: 20140057006
    Abstract: The present invention relates to pharmaceutical compositions for the treatment, and especially topical treatment, of warts and the use thereof for the treatment of warts. Specifically, the present invention relates to pharmaceutical compositions for the treatment of warts, comprising: a) 0.1 to 10 weight % dimethicone; b) 5 to 25 weight % of one or more vegetable oils; c) one or more pharmaceutically acceptable excipients and/or carriers; d) 2 to 6 weight % urea; and e) water up to 100 weight %.
    Type: Application
    Filed: September 17, 2013
    Publication date: February 27, 2014
    Applicant: ATP Marketing & Promotion AG
    Inventor: Mario Dominik Nicolaas Oldani
  • Publication number: 20140044811
    Abstract: A method for relieving or preventing symptoms associated with uric acid crystals, comprising consuming a formulation that supports three or more processes, the processes comprising: 1) one that inhibits formation of uric acid in the body; 2) one that increases elimination of uric acid from the body; and 3) one that interferes with formation of uric acid crystals in the body. Also, a process to make a formulation, comprising mixing together: i. a material that inhibits formation of uric acid in a body; ii. a material that increases elimination of uric acid from the body; iii. a material that interferes with formation of uric acid crystals in the body; and forming the mixture into a medicament.
    Type: Application
    Filed: October 21, 2013
    Publication date: February 13, 2014
    Inventors: Kent J. Truscott, Susan M. Abernathy
  • Patent number: 8637092
    Abstract: The present invention relates to methods for preparing a pharmaceutical composition for treating diabetes mellitus and the pharmaceutical composition prepared by the methods. The pharmaceutical composition of the present invention comprises extracts of the following crude drugs: 5-40 weight parts of Radix Trichosanthis (Tianhuafen), 10-30 weight parts of Radix Bupleuri (Chaihu), 3-15 weight parts of Fructus Aurantii Immaturus (Zhishi), 1-6 weight parts of Radix et Rhizoma Rhei (Dahuang), 1-12 weight parts of Rhizoma Pinelliae (Banxia), 3-15 weight parts of Radix Scutellariae (Huangqin), 1-12 weight parts of Rhizoma Coptidis (Huanglian), 3-15 weight parts of Radix Paeoniae Alba (Baishao) and 5-20 weight parts of Fructus Mume (Wumei), and optionally comprises pharmaceutically acceptable excipient. Also, the pharmaceutical composition of the present invention can further comprise Fructus Crataegi (Shanzha). Additionally, the present invention discloses four methods for preparing the pharmaceutical composition.
    Type: Grant
    Filed: July 28, 2008
    Date of Patent: January 28, 2014
    Assignee: Tasly Pharmaceutical Group Co., Ltd.
    Inventors: Xiaolin Tong, Yonghong Zhu, Shuiping Zhou, Xiuhui E, Shuangming Wang, Zhongting Xia
  • Patent number: 8637096
    Abstract: A new treatment for individuals suffering from type 2 diabetes. The formulation used in the treatment includes a mixture of a thiazoleineione, an insulin, cinnamon bark extract, and at least one synergistic supplement selected from the group consisting of blueberry leaf extract, cranberry extract, kelp extract, sugar sea beet extract, acerola berry extract; ginger root extract, black cherry extract, green tea extract, Irish moss extract, aloe vera extract, and Stevia leaf extract. The thiazoleineione is preferably pioglitazone. The insulin is preferably an Insulin Aspart of rDNA origin. It is preferred that the cinnamon bark extract and synergistic supplement be in the form of a liquid concentrate.
    Type: Grant
    Filed: June 15, 2012
    Date of Patent: January 28, 2014
    Inventor: Curtis C. Stojan
  • Patent number: 8603549
    Abstract: According to the invention, a method for inhibiting the formation of stretch marks is disclosed. The method may include applying an oil to a portion of a person's body. The method may also include placing a non-absorbent film over the oil on the portion of the person's body. The method may further include securing the non-absorbent film to the person's body.
    Type: Grant
    Filed: May 25, 2012
    Date of Patent: December 10, 2013
    Inventor: Svetlana Baker
  • Publication number: 20130309334
    Abstract: The present invention relates to a composition for preventing or treating dementia containing an extract of Prunus mume (Fructus Mume), and the Prunus mume extract of the present invention has outstanding effects in improving spatial recognition ability and in normalizing hippocampal damage (normalizing ERK phosphorylation, increasing ChAT and normalizing NF-kappa B) induced by chronic vascular brain damage in a vascular dementia animal model, and hence can be used to advantage as a medicinal product for preventing or treating dementia diseases and as a functional health food for preventing or alleviating dementia diseases that accompany vascular brain damage such as vascular dementia.
    Type: Application
    Filed: October 4, 2011
    Publication date: November 21, 2013
    Applicant: KOREA INSTITUTE OF ORIENTAL MEDICINE
    Inventors: Won Kyung Jeon, Jung-Soo Han, Chang Hyun Han, Goya Choi
  • Publication number: 20130287871
    Abstract: The invention relates to a novel sweet-tasting refreshing beverage, which is free of phosphoric acid and instead contains at least 0.3% by weight/volume of gluconic acid, which is low in minerals, specifically contains less than 250 mg/liter of minerals, which is low in sugar, specifically contains at most 2.5% by weight/volume of sugar, wherein these sugars comprise at least 10% weight/weight galactose and in addition a proportion of isomaltulose and/or tagatose, and which has a glycemic index of at most 35 (GI<35).
    Type: Application
    Filed: December 20, 2011
    Publication date: October 31, 2013
    Inventor: Johannes Coy
  • Publication number: 20130287870
    Abstract: The present invention relates to the use of one or more Neuroaid2 components to activate KATP channels and in the treatment of various diseases and disorders. The one or more Neuroaid2 components are selected from the group consisting of: Salviae Miltiorrhizae, Prunus persica; Polygalae; acori tatarinowii; Astragali; Paeoniae Rubra; Chuanxiong; Carthamus tinctorius; and angelicae sinensis.
    Type: Application
    Filed: March 25, 2013
    Publication date: October 31, 2013
    Inventors: Hamid MOHA OU MAATI, Michel LAZDUNSKI, Catherine HEURTEAUX, David PICARD