Abstract: The present invention provides nanoparticulate nimesulide compositions. The compositions preferably comprise nimesulide and at least one surface stabilizer adsorbed on or associated with the surface of the nimesulide particles. The nanoparticulate nimesulide particles preferably have an effective average particle size of less than about 2000 nm. The invention also provides methods of making and using nanoparticulate nimesulide compositions.

Abstract: The therapeutic ultrasound gel is a composition that lubricates the abdomen for ultrasound scanning, that enhances the transmission of sound waves during ultrasound diagnostic imaging, and that has beneficial therapeutic effects in preventing the formation of stretch marks. The composition contains effective amounts of aloe vera (Aloe barbadensis), glycerin, and various agents for preventing the formation of stretch marks, with the balance being sufficient water to adjust the consistency of the composition. The composition may also be formulated for home use, chiefly by the addition of vitamin D3 or, alternatively, vitamin K. Either formulation may contain additional excipients, including surfactants, emulsifiers, humectants, stabilizers, thickeners, pH balancers, preservatives, colorants, and scent, if desired.

Abstract: A weight loss product comprises a mixture of Alchemilla vulgaris, Olea europaea, Cuminum cyminum, and Mentha longiflora (in the weight proportion 12:10:5:4), to which additional ingredients have been added to increase weight loss efficacy.

Abstract: This invention relates to an externally applied ointment that aids in relieving irritation, pain or mild inflammation of the skin or mucous membranes associated with hemorrhoids and the method of using such ointment lotion. The formulation of the present invention contains phenylephrine HCl, lidocaine grape skin/seed/leaf extract and aloe plants extract.

Abstract: The present invention is directed to transdermal compositions and the uses thereof. These compositions include at least one of the following components: a C1-C6 dialkyl, C12-C30 dialkyl quaternary ammonium salt, a C12-C30 fatty acid, a nitrogenous organic base, C12-30 fatty alcohol, monoglyceride or the reaction products thereof.

Abstract: A method for cutaneous treatment of Herpes simplex infections by applying topically to the area of outbreak a composition comprising at least 1% by weight D-Lenolate® olive leaf extract. A composition for treatment is also disclosed, containing, by weight, at least 1% D-Lenolate® olive leaf extract, 1-3% neem, 0.05-1% aloe and 0.05-1% menthol.

Abstract: Disclosed herein are compositions and methods for use of such for clotting blood. In one example, a disclosed composition includes at least Stachys betonica, Achillea millefolium, Marrubium vulgare, and Urtica dioica. Methods of use of the disclosed compositions are also provided, including methods of preventing or inhibiting a nosebleed, bleeding associated with a hemorrhoid or bleeding associated with a wound, such as a cut or abrasion.

Abstract: A preparation for vaginal and rectal use comprising hyaluronic acid, with an average particle size comprised between about 50 micrometers and about 200 micrometers and a molecular weight comprised between about 1,000,000 Da and about 1,800,000 Da.

Abstract: The invention is a new unique, palatable, topical, anti-inflammatory and analgesic designed around a specific set of painful conditions, with specifically designated applications, using a different methodology and formulation, with no NSAIDS, steroids or salicylites, than the prior art for this specific set of painful conditions. Thus creating an improved dissimilar system, preventing the prior arts required invasive, costly and inefficient medical procedures, and with a unique lack of negative effects when compared with the prior art. Thereby, facilitating an anti-inflammatory analgesic effect to areas correlating or relating to the trigeminal nervous system, both intraoral and extraoral.

Abstract: Personal care formulations containing alkyl ketal esters having the structure wherein a is 0 or an integer of 1 to 12; b is 0 or 1; R2 is a divalent C1-8 group optionally substituted with up to 5 hydroxyl groups; and R1 is C1-6 alkyl.

Abstract: Compositions and methods for treatment of dermal scarring and wrinkling, by application to the skin of a cosmetically effective amount of Plantago major or Plantago Lanceolata. The plantain may be utilized in powdered form in an aqueous paste or poultice, or in a crème base or ointment that is applied to the skin for various periods of time from 1 to 10 hours at a frequency of 1-12 times per week, for a period of 3-50 weeks or more. The composition is effective to remediate dermal scarring and wrinkling, and at least partially restore skin to an undamaged, undeteriorated state.

Abstract: A combination of chemical agents reduces reductive stress by limiting the accumulation of high-energy electrons potentially available to the electron transport chain. A method of metabolic uncoupling therapy comprises: analyzing a specific physiologic process involving reductive stress; identifying a plurality of MUT agents that modulate metabolic pathways by influencing electron flux; and formulating a combination of MUT agents that limits the accumulation of high-energy electrons potentially available to the electron transport chain.

Abstract: A substantially non-aqueous, aerated composition is free of petroleum-based components and is suitable for skin applications. The composition primarily includes wax and oil, and can further include vitamin E oil and an essential oil. The composition can be a semi-solid at room temperature. A method of making the composition includes melting together component ingredients to form a mixture, which is then cooled to form hardened matter. The hardened matter is blended to form a flowable mixture, which is then forced through a sieve to form the aerated composition.

Abstract: Cleansing compositions are described that comprise at least one surfactant, at least one extract of a Lamiaceae family plant, and at least one extract of a Liliaceae family plant. The at least one extract of the Lamiaceae family plant and the at least one extract of the Liliaceae family plant are present in effective amounts to at least partially counteract skin irritation induced by the at least one surfactant. Methods of reducing skin irritation induced by a surfactant comprise contacting skin with a detergent comprising at least one surfactant, at least one extract of a Lamiaceae family plant, and at least one extract of a Liliaceae family plant, wherein the at least one extract of the Lamiaceae family plant, and the at least one extract of the Liliaceae family plant at least partially counteract irritation induced by the at least one surfactant.

Abstract: The present invention provides an ointment comprising aqueous extract of fig leaves, horse chestnut, artichoke leaves and walnut shells, for the treatment of haemorrhoids; a method of manufacturing such an ointment; and the use of fig leaves, artichoke leaves or walnut shells for the manufacture of a medicament for the treatment of haemorrhoids. Preferably, the ointment further comprises lanolin and petroleum gelly (Vaseline). Preferably, the method comprises extracting fig leaves, horse chestnut, artichoke leaves and/or walnut shells using heated water, and admixing thereto lanolin and petroleum gelly (Vaseline) so as to result in the ointment. The ointment preferably further comprises ‘Huile de Cade’.

Abstract: An oil-based composition for application to mucosal surfaces of the human body provides potent activators of cytoprotective antioxidants. The composition includes the following ingredients: soy oil; coconut oil; orange oil; peppermint oil; aloe vera oil; vitamin E; and may further include jojoba and a preservative. Application of the composition increases expression of antioxidant genes and inhibits proinflammatory action caused by exposure to oxidant pollutants, allergens and other cytotoxins.

Abstract: Activated fatty acids, topical compositions including activated fatty acids and methods for using activated fatty acids to treat a variety of diseases.

Abstract: There is provided a topical foaming composition for the uniform distribution of formulations without drizzle formation. In accordance with the present invention, the topical composition contains a foaming agent and a pharmaceutically acceptable topical carrier. In accordance with the present invention, the composition may contain at least one active agent incorporated into the topical foaming composition. In accordance with a method of the present invention, the composition is capable of forming a stable foam in the present of a gas and the foam produced therefrom is topically applied on a subject in need thereof.

Abstract: Disclosed is a self-adhesive matrix system comprising a styrene-ethylene/butylene-styrene (SEBS) copolymer in an oil/ethyl acetate mixture, a hydrogenated resin and a pharmaceutical or cosmetic active ingredient.

Abstract: A method for passively reducing nosocomial infections by providing fabrics for patient contact only as media for air filtration in areas with patient populations, which fabrics have been treated with a solution of eugenol of sufficient strength and for sufficient time to reduce the percentage of viable microbes in the fabrics by at least 2 log units.

Abstract: The present disclosure provides hydrogels that are suitable for drug delivery. In embodiments, hydrogels of the present disclosure may be used for transdermal delivery of bioactive agents, including drugs. The hydrogels of the present disclosure may also be useful as conductive compositions for use with electrodes.

Abstract: An antimicrobial fabric and method for treating fabric to impart antimicrobial properties thereto by preparing an aqueous solution of eugenol, polyvinyl alcohol, and glyoxal, padding the fabric with the aqueous solution to achieve a preselected desired part by weight wet pickup, drying the fabric; and curing the fabric.

Abstract: The method of human prophylaxis comprising a number of steps is claim. First, the client is prepared for a steam bath, by applying a herbal paste on the skin, over at least one area of the client's body. The herbal paste is allowed to be absorbed into the client's body for an amount of time of at least five minutes and is followed with a massage the client's body. The client is then placed into a cedar steam barrel, connected to the steam generator, where the client's body is exposed to the steam. Following the stream procedure, the herbal paste is reapplied, the client's body is massaged, and the client to rests and drinks at least one cup of tea.

Abstract: The present invention provides compositions containing one or more antimicrobial peptide sequestering compounds and methods for topical application of such compositions to the skin to treat skin diseases and disorders such as rosacea in humans.

Abstract: An emulsion composition, methods of softening fibrous structures using the same, and fibrous substrate treated therewith. The composition comprising: (A) 0.01 to less than 25.0 parts by weight of a diorganopolysiloxane; (B) 0.01 to less than 20.0 parts by weight of softening agents; (C) 8.0 to 60.0 parts by weight of water; and (D) 20.0 to 90.0 parts by weight of water-soluble monovalent or polyvalent alcohols, wherein the continuous phase of said emulsion composition is an aqueous solution consisting of said (C) water and said (D) water-soluble monovalent or polyvalent alcohols in the ratio of from 1:0.5 to 1:10, and total content of said component (C) and (D) is in the rage of 30.0 and 98.0 parts by weight of said emulsion composition.

Abstract: A composition comprising vegetable/herbal-based dietary ingredients, or extracts, which contains vitamins and nutrients that provide a novel nontoxic treatment for liver cancers, hepatitis, and liver cirrhosis. The composition can be taken as a daily dietary supplement to enhance normal physiological functions of the body. The said composition, or extracts thereof, are useful and effective in the treatment and prevention of liver and possibly other cancers. The compositions are also useful for administration to patients with pre-existing hepatitis and/or liver cirrhosis. The compositions or extracts thereof may be useful for treating other cancers and other disorders, diseases, or conditions.

Abstract: The present invention describes systems and methods for treating disorders and/or conditions associated with the dermal level of the skin. Such disorders include acne, hyperhidrosis, bromhidrosis, chromhidrosis, rosacea, hair loss, dermal infection, and/or actinic keratosis. Methods generally involve administering nanoemulsions (e.g., nanoparticle compositions) comprising at least one therapeutic agent, such as botulinum toxin. In some embodiments, nanoemulsions are prepared, e.g., by high pressure microfluidization, and comprise a particle size distribution exclusively between 10 nm and 300 nm.

Abstract: The present invention relates to a product for topical administration in particular, a product for use in the treatment of eczema and psoriasis and other related conditions.

Abstract: The present invention relates to personal care compositions, especially those shave preparation article and skin care articles which are in the form of a porous dissolvable solid substrate having a surface resident coating comprising at least one skin treatment active. The present invention can deliver a consumer benefit as well as allow for separation of any incompatible actives in the substrate versus the coating.

Abstract: Nanoparticulate compositions comprising at least one poorly soluble MAP kinase inhibitor and at least one surface stabilizer are described. The nanoparticulate compositions have an average particle size of less than about 2000 nm. The invention also describes methods of making and using such compositions.

Abstract: The invention relates to a method of treating the coat of an animal. The method includes the steps of applying a composition to the coat of the animal, diffusing the composition by action of a carrier, storing the active ingredients of the composition by the sebaceous glands of the animal, and gradually releasing the active ingredients from the sebaceous glands. The dermo-cosmetic composition includes a diffusion solvent vehicle that enables, by a simple application to one or more points of the cutaneous surface, a diffusion over the entirety thereof and at the level of the sebaceous glands. The active ingredients, primarily including a complex of essential oils and of polyunsaturated fatty acids, stored in these sebaceous glands can be salted out progressively with the sebum product to the surface of the skin.

Abstract: Cosmetic or dermopharmaceutical compositions containing Pseudoalteromonas ferment extract for the treatment and/or care of the skin, scalp and/or nails, preferably to improve the barrier function of the skin, scalp and/or nails, and specifically for the treatment and/or care of those conditions, disorders and/or pathologies of the skin, scalp and/or nails associated with an alteration in the keratinization process.

Abstract: Methods and compositions for treating skin conditions in animals, which tend to have higher skin pH than humans, including wounds, ulcers, rashes, burns, abrasions, and other irritations and relevant injuries are provided. The invention contemplates the use of an aqueous or emollient medium having non-occlusive properties with one or more pH raising ingredients in a composition specifically designed to deliver oxygen to the skin's surface.

Abstract: The present invention relates to a composition containing at least one nutritive, at least one disinfecting or decontaminating and/or at least one protease-inhibiting active compound and/or active compound complex for the external care and/or treatment of wounds of the human or animal body.

Abstract: The present invention relates a new composition based on a mixture of a solvent, aloe vera, and sulfur. More particularly the present invention describes a solvent that contains a certain arrangement of minerals which when combined with solid sulfur and aloe vera provide a topical solution that can alleviate pain and rapidly progress healing time of burns of the skin.

Abstract: The present invention provides a pharmaceutical composition comprising a chemical compound or a herb extract or the combination having at least one of the activities of antiviral, antibacterial, antifungal, anti-inflammatory, anti-allergy, anti-cancer, promoting membrane healing or immunomodulating, for the treatment and prevention of a disease of a mammal. The present invention also provides a system for delivering the composition to the hard-to-reach sinuses of a mammal to reduce the load of the pathogen, to reduce the amount of inflammatory mediators, to heal pathological changes, and collectively to treat a disease of a mammal, such as allergic fungal rhinosinusitis. The invented method of treating a human disease reduces infectious and inflammatory agents without causing antibiotic resistance or adverse event.

Abstract: A composition including one or more of elecampane rhizome (Inula sp.), fennel fruit (Foeniculum sp.), juniper berry (Juniperus sp.), licorice root (Glycyrrhiza sp.), oregano herb (Oreganum sp.), marigold flowers (Calendula sp.), rose hips (Rosa sp.), and thyme (Thymus sp.), or an extract thereof. The composition is useful for treating infectious diseases, for example viral and microbial infections, and for reducing the toxic effects of chemotherapeutic agents.

Abstract: A unique, synergistic formulation for the treatment of first-degree skin burns is provided for topical use and alleviates the full spectrum of symptoms and concerns associated with epidermal burns, including pain, blistering, redness, swelling, compromised skin integrity, risk of infection and scarring. The formulation contains natural homeopathic extracts combined with a pharmaceutically acceptable carrier suitable for topical administration. The formulation includes the following homeopathic extracts: Cantharis vesicatoria, Echinacea anqustifolia, Calendula officinalis and Hypericum perforatum.

Abstract: A new treatment for individuals suffering from type 2 diabetes. The formulation used in the treatment includes a mixture of a thiazoleineione, an insulin, cinnamon bark extract, and at least one synergistic supplement selected from the group consisting of blueberry leaf extract, cranberry extract, kelp extract, sugar sea beet extract, acerola berry extract; ginger root extract, black cherry extract, green tea extract, Irish moss extract, aloe vera extract, and Stevia leaf extract. The thiazoleineione is preferably pioglitazone. The insulin is preferably an Insulin Aspart of rDNA origin. It is preferred that the cinnamon bark extract and synergistic supplement be in the form of a liquid concentrate.

Abstract: The invention relates to a dermatological pharmaceutical composition for the treatment of skin inflammation diseases, such as dermatitis, atopic dermatitis, vitiligo, alopecia areata, acne, psoriasis and pruritus. The invention comprises a base anti-inflammatory agent, such as indometacin; one or more optional active ingredients selected alternatively from among at least a corticoid and an antibiotic; and a combination of topical antioxidants used to potentiate the anti-inflammatory effect, selected from among green tea, lipoic acid, curcumin, ascorbyl palmitate, Coenzyme Q10, resveratrol, Pycnogenol™, L-camosine, taurine, vitamin E, vitamin C, papaya extract, isoflavones, manganese, lycopene and quercetin. At least one of the topical antioxidants is a peroxisome proliferator-activated receptor-gamma (PPAR-?) activator. The invention also includes at least one antioxidant substance with an antiproliferative effect on keratonocytes, e.g.

Abstract: This invention describes method to facilitate intradermal delivery of a great variety of active substances, especially including high molecular weight cosmicuticals. Also disclosed is a method of applying the composition of matter resulting from the method topically to patients, especially using a cream or patch. The active substance is initially combined with a biopolymer, which combination is subsequently linked to a base formulation whereby the base formulation aids in the intra-dermal delivery of the active substance without the skin irritation limitations of other formulations and dermal transmitting methods. The method of using a combination of natural herbal, vegetable and animal products combined in this invention with biopolymers permits molecules of higher molecule weight to penetrate into the skin in a bioactive form by passive delivery means. The invention includes a method for the improvement of skin health and wrinkle reduction.

Abstract: A method and composition for the treatment of diabetic neuropathy is disclosed. A preferred embodiment of the invention relates to a topical composition for the treatment of systems related to diabetic neuropathy by application to the affected area. The composition provides relief of these symptoms and inhibits those factors that contribute to these systems, such as an aldose reductase inhibitor. A preferred embodiment of the invention relates to a method of treatment for diabetic neuropathy utilizing a regime of administrations of a topical composition in amounts effective to counter those areas of the body affected by peripheral Neuropathy. Yet another preferred embodiment of the invention relates to a method of improvement of those areas effected by diabetic peripheral neuropathy using a topical composition over an effective period of time.

Abstract: The invention relates to ether guanidines of the general formulae (I) and/or salts or hydrates thereof, in which R1=—CH2—CH2—CH2—O—R3 where R3 is, independently of the others, hydrocarbon radicals having greater than or equal to 10 carbon atoms, where part of the ether guanidines has radicals R3 which are branched and part of the ether guanidines has radicals R3 which are unbranched, and R2=independently of the others H or an optionally branched, optionally double-bond-containing hydrocarbon radical having 1 to 30 carbon atoms, and use thereof in hair treatment compositions and hair aftertreatment compositions, in particular for preventing damage by chemical treatment compositions and for repairing hair which is already damaged.

Abstract: The present invention generally relates to a wet wipe or sheet that is suitable for contacting the skin and removing mucus from the skin. More specifically, the present invention relates to a wet wipe having an aqueous saline component suitable for dissolving and removing mucus in combination with the fabric matrix of the wet wipe. Typically, the fabric matrix of the wet wipe has a capacity of about 125 grams of solution per square meter, and it is impregnated with the aqueous saline solution to a level at or below approximately 80% of the absorbent capacity of the matrix.

Abstract: The present invention is directed to the use of an agent selected from ethyl alcohol, isopropyl alcohol or a mixture thereof and a topically acceptable polymeric carrier in the preparation of a composition for the treatment of burns.

Abstract: The present invention provides: an Aloe vera extract that can be safely ingested, can be used as a material of food for preventing lifestyle diseases, contains an extremely low level of an anthraquinone (anthraquinone-based compound), and can be added to foods; and a method of producing the Aloe vera extract. A supercritical fluid extraction method can produce an Aloe vera extract containing a mixture that consists of a cyclolanostane compound and a lophenol compound in an amount of 1.0% by mass or more and having the following properties (1) and/or (2): (1) the mass mixing ratio of the cyclolanostane compound and lophenol compound is as follows: cyclolanostane compound:lophenol compound=6.3:2.7 to 5.1:4.9; and/or (2) the content of an anthraquinone-based compound is 0.001% by mass or less.

Abstract: The present invention relates to a composition comprising panthenol, a collagen synthesis stimulating peptide and an anti-inflammatory extract. The compositions are particular useful for preventing and treating stretch marks.

Abstract: Methods and devices for the stabilization of heart tissue to treat congestive heart failure using a therapeutic composition are discussed. The therapeutic composition can comprise an elastin stabilization agent, a collagen stabilization agent, or a combination thereof and be applied to the pericardium, to the outer surface of the myocardium, or a combination thereof using a catheter type of device with an attached reservoir. Controlled placement and release of the therapeutic composition can be achieved using a delivery vehicle to formulate the composition.

Abstract: A method for cutaneous treatment of Herpes simplex infections by applying topically to the area of outbreak a composition comprising at least 1% by weight D-Lenolate® olive leaf extract. A composition for treatment is also disclosed, containing, by weight, at least 1% D-Lenolate® olive leaf extract, 1-3% neem, 0.05-1% aloe and 0.05-1% menthol.

Abstract: A topical pain formulation, comprising one or more analgesic compounds and a plurality of skin penetrants.