Containing Or Obtained From Zingiberaceae (e.g., Afromonun, Cardemon, Ginger, Turmeric, Etc.) Patents (Class 424/756)
  • Patent number: 11298395
    Abstract: The present invention relates to a process for the isolation of bioactive components from spent turmeric (Curcuma longa) and compositions comprising said bioactive components. Further, the present invention also elucidates the potent anti-inflammatory activity of said bioactive compositions and therapeutic applications thereof in rheumatoid arthritis.
    Type: Grant
    Filed: July 17, 2018
    Date of Patent: April 12, 2022
    Assignee: SAMI LABS LIMITED
    Inventors: Muhammed Majeed, Kalyanam Nagabhushanam, Beena Bhat, Natarajan Sankaran
  • Patent number: 11224630
    Abstract: The present invention relates to the field of health care food technology, specifically to a traditional Chinese medicine composition with a function of protecting joints, a use thereof, a method for producing the same and a health care food thereof. The Chinese medicine composition comprises CURCUMAE LONGAE RHIZOMA extract, cartilage extract, COICIS SEMEN extract and PUERARIAE LOBATAE RADIX extract. The composition of the present disclosure has a reasonable formulation, and the ingredients cooperate with each other to achieve functions of reducing arthrocele degree, decreasing arthritis index, ameliorating biochemical index of arthritis and reducing articular cavity area through various paths and at various levels.
    Type: Grant
    Filed: May 17, 2019
    Date of Patent: January 18, 2022
    Assignee: INFINITUS (CHINA) COMPANY LTD.
    Inventors: Liugang Ding, Zhongbao Yue, Danlin He, Yong Zhou, Jian Tang
  • Patent number: 11147850
    Abstract: The present invention relates to synergistic compositions for the treatment of one or more associated conditions of arthritis or rheumatoid arthritis osteoarthritis. More particularly, novel synergistic compositions which comprises a combination of therapeutically effective amounts of: a) an alcoholic/hydroalcoholic extract of Tamarindus indica seed comprising proanthocyanidins either alone or in combination with water extract of Tamarindus indica seed comprising polysaccharides, b) a Curcuma longa rhizome extract comprising curcuminoids, c) optionally containing pharmaceutically or nutraceutically or dietetically acceptable carriers/excipients. The invention also relates to a method of treating one or more associated conditions of arthritis or rheumatoid arthritis or osteoarthritis using synergistic composition.
    Type: Grant
    Filed: October 9, 2015
    Date of Patent: October 19, 2021
    Assignee: Laila Nutraceuticals
    Inventors: Ganga Raju Gokaraju, Rama Raju Gokaraju, Venkata Kanaka Ranga Raju Gokaraju, Trimurtulu Golakoti, Kiran Bhupathiraju
  • Patent number: 11110146
    Abstract: The invention provides therapeutic compositions containing ground seed of Aframomum meleguata or an extract thereof, and methods for using such compositions to reduce platelet aggregation and treat medical disorders in a patient, such as cardiovascular disease.
    Type: Grant
    Filed: December 18, 2015
    Date of Patent: September 7, 2021
    Assignee: Paradise Health, Inc.
    Inventors: Curt Hendrix, Jack Joseph Kleid
  • Patent number: 10966938
    Abstract: A composition for treating the symptoms of a hangover. The composition is provided in the form of a capsule, pill, liquid, powder for mixing, or patch. The composition includes a therapeutically effective amount of cannabidiol, an antioxidant blend, a detox blend, and a hydration blend. The antioxidant blend includes prickly pear, acai berry extract, and taurine. The detox blend includes milk thistle, dihydromyricetin, glutamine, branched chain amino acids, inositol, and pepper. The hydration blend includes electrolytes, vitamins, and N-acetyl cysteine.
    Type: Grant
    Filed: January 6, 2020
    Date of Patent: April 6, 2021
    Inventor: Jonathan B. Andry
  • Patent number: 10945970
    Abstract: Methods and compositions for increasing LDL receptor levels in a plurality of cells are disclosed. For example, the methods include providing to the cells a curcumin composition that is at least 15% curcumin II or at least 5% curcumin III, in order to increase LDL receptor levels. In addition, compositions for increasing LDL receptor levels in a plurality of cells are disclosed, which include a curcumin composition consisting of at least 15% curcumin II or at least 5% curcumin III (or combinations of such curcuminoids), along with a pharmaceutically-acceptable solvent, filler, or carrier. Still further, methods and compositions for decreasing MSK1 levels in a plurality of cells are disclosed, which involve administering a curcumin III-enriched composition to the cells.
    Type: Grant
    Filed: August 24, 2018
    Date of Patent: March 16, 2021
    Inventor: Franco Cavaleri
  • Patent number: 10898464
    Abstract: The present invention relates to a composition for use in the treatment of an intestinal tract disorder caused by a gluten-associated protein, said composition comprising at least one agent which binds to the gluten-associated protein, characterized in that the composition is administered at the same time as or at most within 60 minutes after administration of at least one tannin to a patient.
    Type: Grant
    Filed: June 30, 2017
    Date of Patent: January 26, 2021
    Assignee: STADA ARZNEIMITTEL AG
    Inventor: Albert Missbichler
  • Patent number: 10857089
    Abstract: Suggested is a cosmetic composition comprising an anti-pollution agent selected from the group consisting of purple coneflower pressed juice, sclareolide, ginger root C02 extract, E/Z-2-benzylindene-5,6-dimethoxy-3,3-dimethylindan-1-one or mixtures thereof, in a working amount sufficient for (a) reducing or preventing air pollution induced gene expression, and/or (b) reducing or preventing a gene expression induced or inducible by polycyclic aromatic hydrocarbons, and/or (c) reducing or preventing air pollution-induced or air pollution-inducible skin damage.
    Type: Grant
    Filed: May 25, 2016
    Date of Patent: December 8, 2020
    Assignee: Symrise AG
    Inventors: Jean Krutmann, Imke Meyer, William Johncock, Gerhard Schmaus, Marielle le Maire, Martina Herrmann
  • Patent number: 10857124
    Abstract: The present invention includes compositions and methods for modifying the expression of microRNAs comprising: one or more plant secondary metabolites capable of beneficially regulating different genes in the human genome by modifying the expression of one or more microRNAs, wherein the one or more plant secondary metabolites are selected and provided in an amount selected to target the modification of one or more specific microRNA.
    Type: Grant
    Filed: August 21, 2019
    Date of Patent: December 8, 2020
    Assignee: PERFORMANCE LABS PTE. LTD.
    Inventor: Daniel Gubler
  • Patent number: 10857186
    Abstract: A traditional Chinese medicine composition for treating acute stage of cerebral infarction. The traditional Chinese medicine composition combines buffalo horns, unprocessed rehmannia roots, red paeony roots, cortex moutan, grassleaf sweelflag rhizome and turmeric root-tuber, and exerts the synergistic effects of the medicines through compatibility, thereby being capable of more effectively clearing away heat and toxic materials, cooling the blood, dissipating blood stasis and inducing resuscitation, and achieving the purpose of treating acute stage of cerebral infarction.
    Type: Grant
    Filed: March 11, 2020
    Date of Patent: December 8, 2020
    Assignee: Jiangsu Province Institute of Traditional Chinese Medicine
    Inventors: Hongquan Liu, Xiaolan Cheng, Jingbo Li, Mingming Fang, Shuting Jiang, Yudi Lu, Jie Gong
  • Patent number: 10772925
    Abstract: The present invention relates to a composition comprising a dry preparation of Alpinia galanga (L.) Willd (Zingiberaceae) or Alpinia conchigera Griff and a plant extract comprising compounds with anti-oxidative activity, such as an extract of Punica granatum. Also disclosed herein is a method of improving semen quality by administering said composition to a male subject in need thereof.
    Type: Grant
    Filed: June 6, 2014
    Date of Patent: September 15, 2020
    Assignee: NERTHUS APS
    Inventors: Ina Giversen, Henrik Jakobsen
  • Patent number: 10758551
    Abstract: It was discovered that NF-?B signaling pathway plays a central role in pancreatitis, and inhibition of NF-?B signaling has the potential to reduce the incidence of pancreatitis and protect pancreatic tissues from inflammatory damage. Aspects of the disclosure relate to a method for inhibiting or treating pancreatitis in a subject in need thereof comprising administering a therapeutically effective amount of an NF-?B signaling pathway inhibitor to the subject.
    Type: Grant
    Filed: March 30, 2016
    Date of Patent: September 1, 2020
    Assignee: Baylor Research Institute
    Inventors: Mazhar Adnan Kanak, Bashoo Naziruddin, Marlon F. Levy
  • Patent number: 10745755
    Abstract: The disclosure relates to the identification and the use of compounds which regulate the expression of at least one Sestrin gene, for preventing and/or attenuating skin ageing, and/or for hydrating the skin and/or for regulating skin pigmentation. The method includes the following steps: a. bringing at least one test compound in contact with a sample of human keratinocytes or melanocytes; b. measuring the expression of at least one Sestrin gene chosen from SESN3, SESN2 and SESN1 in the keratinocytes or melanocytes; c. selecting the compounds for which an activation of at least 1.6 fold of the expression of at least one of the genes is measured in the keratinocytes treated in a. compared with the untreated keratinocytes, or for which a significant modulation of the expression of at least one of the genes is measured in the melanocytes treated in a. compared with the untreated melanocytes.
    Type: Grant
    Filed: September 25, 2015
    Date of Patent: August 18, 2020
    Assignee: CHANEL PARFUMS BEAUTE
    Inventors: Gaelle Gendronneau, Irina Berlin, Francois Lejeune, Julie Latreille
  • Patent number: 10710002
    Abstract: A method of extracting nutrients from a plant includes the steps of: pulverizing a water soluble nutrient-based plant part of a first plant material of the plant so as to form a first pulverized plant part; pulverizing a lipid soluble nutrient-based plant part of a second plant material of the plant so as to form a second pulverized plant part; subjecting the first pulverized plant part to a distillation so as to obtain a distillate and a first residue that contains a water soluble nutrient; and immersing the second pulverized plant part in the distillate to form a first mixture followed by distillation of the first mixture, so as to obtain a second residue that contains a lipid soluble nutrient.
    Type: Grant
    Filed: January 17, 2017
    Date of Patent: July 14, 2020
    Assignee: NUECOLOGY BIOMEDICAL INC.
    Inventors: Chung-Chin Sun, Yeuh-Hui Lin, Shan-Shue Wang
  • Patent number: 10695302
    Abstract: The present invention provides a method of treating or preventing an attention and/or cognitive disorder in a subject in need thereof, comprising administering to the subject a compound useful within the invention. The present invention further provides a method of treating or preventing dementia associated with a neurodegenerative disorder in a subject in need thereof, comprising administering to the subject a compound useful within the invention.
    Type: Grant
    Filed: November 22, 2017
    Date of Patent: June 30, 2020
    Assignee: Drexel University
    Inventor: Sandhya Kortagere
  • Patent number: 10688146
    Abstract: A preparation comprises a herbal extract and/or fraction, and a pharmaceutical preparation includes extract of Curcuma mangga Val. et Zipp., which has bioactivities in reducing expression levels of 5-alpha-reductase-1, androgen receptor, and PI3 in prostate cancer cells. The use of this present invention is directed to reduce prostate enlargement. Moreover, it also can be used to treat prostate cancer, lung cancer, and other diseases related to GPCR pathway.
    Type: Grant
    Filed: May 21, 2018
    Date of Patent: June 23, 2020
    Assignee: PT Dexa Medica
    Inventors: Asep Aripin, Agung Heru Karsono, Olivia Mayasari, Priska Hardadi, James M. Sinambela, Raymond R. Tjandrawinata
  • Patent number: 10631546
    Abstract: [Problem] To produce a frozen bread dough improver that has an effect of improving rising of frozen bread dough, is highly safe, and tasteless, using a method that is low-cost and low in environmental impact. Also, to effectively use yeast cell body residue produced as a byproduct of yeast extract. [Means for Solving the Problem] Yeast cell body residue remaining after extracting useful extract from yeast is suspended in water and heated, after which the suspension is subjected to centrifugal separation and a supernatant is obtained. This fraction contains, per solid content, at least 45 wt % RNA, at least 5 wt % dietary fiber, and at least 10 wt % protein, and mannan content in the dietary fiber is at least 60 wt %. This can be used to improve rising of frozen bread dough.
    Type: Grant
    Filed: August 28, 2015
    Date of Patent: April 28, 2020
    Assignees: MITSUBISHI CORPORATION LIFE SCIENCES LIMITED, THE SCHOOL CORPORATION KANSAI UNIVERSITY
    Inventors: Hidehisa Kawahara, Eiji Nakao, Kenichi Ason, Sakiko Ikeda
  • Patent number: 10568853
    Abstract: Described herein are compositions comprising capsaicin and methods of treating muscle cramping in a subject, comprising orally administering to the subject a composition comprising capsaicin and an excipient.
    Type: Grant
    Filed: August 19, 2016
    Date of Patent: February 25, 2020
    Assignee: Cliff-Cartwright Corporation
    Inventors: Bruce P. Bean, Donald MacKinnon, Roderick MacKinnon
  • Patent number: 10568925
    Abstract: The invention concerns carbon dioxide extracts of Curcuma amada (mango ginger), including supercritical carbon dioxide extracts of C. amada; methods for their production; compositions comprising the extracts; methods for treating or delaying the onset of conditions such as cell proliferation disorder (e.g., cancer), inflammation, infection, hyperlipidemia, hypercholesterolemia, hypertriglyceridemia, hyperglycemia, platelet hyper-aggregation, immune disorder such as autoimmune disorder, or neurodegenerative condition; and methods for inhibiting expression of Bcl-2, Bak, and p53 genes; inhibiting expression of the COX-2 and NF-kB genes, inhibiting production of phosphorylated target of rapamycin (TOR), modulating AMP-activated protein kinase (AMPK), inhibiting protein kinase B (AKT) signaling, modulating the Ras/Raf/MEK/ERK signaling pathway, and modulating the Ras/PI3K/PTEN/Akt/mTOR signaling pathway.
    Type: Grant
    Filed: January 31, 2016
    Date of Patent: February 25, 2020
    Assignees: DHARMA BIOMEDICAL, LLC, FLAVEX NATUREXTRAKTE GMBH
    Inventors: Steven J. Melnick, Karl-Werner Quirin, Cheppail Ramachandran, Melvin Rothberg
  • Patent number: 10532078
    Abstract: The invention relates to a method for producing an extract of a matrix of vegetable origin, particularly a plant, characterised in that the matrix of vegetable origin undergoes a mechanical treatment consisting in extruding the matrix of vegetable origin in an extruder, in association or not with a heat treatment, in the presence of an aqueous solution containing at least one hydrotrope agent, particularly at a concentration at least equal to the minimum hydrotrope concentration thereof, followed by an operation of recovering the extract.
    Type: Grant
    Filed: March 18, 2016
    Date of Patent: January 14, 2020
    Assignee: PIERRE FABRE DERMO-COSMETIQUE
    Inventors: Anne Mandeau, Mathieu Leti
  • Patent number: 10485843
    Abstract: A composition having a curcuminoid and an essential oil of turmeric. A composition having a curcuminoid and an essential oil of turmeric, wherein the essential oil is present in an amount sufficient to cause an enhancement of bioavailability of curcumin when the composition is administered to a human as compared to bioavailability of curcumin obtained upon administration of a composition prepared without adding essential oil to the curcuminoid. A method to prepare a composition having a curcuminoid and an essential oil of turmeric.
    Type: Grant
    Filed: August 29, 2017
    Date of Patent: November 26, 2019
    Assignee: ARJUNA NATURAL PRIVATE LIMITED
    Inventor: Benny Antony
  • Patent number: 10463699
    Abstract: Disclosed is a method of reducing the rancid fish odor smell in a topical composition comprised of fish oil which comprises mixing the composition with monolaurin. Also disclosed are various anhydrous topical compositions comprising fish oil. One comprises fish oil, cetyl ester, palm olein, medium-chain triglyceride(s) of a mixture of C8 and C10 fatty acids, mixture of C8/C10 fatty acids, and monolaurin, another one comprises fish oil, cetyl ester, palm olein, medium-chain triglyceride(s) of a mixture of C8 and C10 fatty acids, mixture of C8/C10 fatty acids, monolaurin, collagen and sea salt, an a third one comprises fish oil, cetyl ester, palm olein, medium-chain triglyceride(s) of a mixture of C8 and C10 fatty acids, mixture of C8/C10 fatty acids, monolaurin and hydrocolloid. These compositions are useful for treating wounds and skin conditions.
    Type: Grant
    Filed: April 4, 2017
    Date of Patent: November 5, 2019
    Assignee: Omeza LLC
    Inventor: Griscom Bettle, III
  • Patent number: 10426756
    Abstract: The present invention includes compositions and methods for modifying the expression of microRNAs comprising: one or more plant secondary metabolites capable of beneficially regulating different genes in the human genome by modifying the expression of one or more microRNAs, wherein the one or more plant secondary metabolites are selected and provided in an amount selected to target the modification of one or more specific microRNA.
    Type: Grant
    Filed: August 4, 2017
    Date of Patent: October 1, 2019
    Assignee: PERFORMANCE LABS PTE. LTD.
    Inventor: Daniel Gubler
  • Patent number: 10383910
    Abstract: The present disclosure relates to a method of increasing fertility of a male subject, wherein the male subject suffers from reduced fertility resulting from a medication, wherein the medication inhibits sperm cell production by inhibiting spermatogenesis in a testis of the male subject, and wherein the method comprises administering to the male subject an effective amount of an extract of Costus speciosus in combination with the medication to prevent, and/or reduce the inhibition of sperm cell production by the medication to increase the fertility of the male subject.
    Type: Grant
    Filed: November 8, 2016
    Date of Patent: August 20, 2019
    Assignee: King Abdulaziz University
    Inventors: Dalia Mostafa Mohammed Domiaty, Sherifa Shaker Hamed Hassaballa
  • Patent number: 10286027
    Abstract: A sustained release curcuminoid composition having a bioavailable curcumin composition and a release rate controlling excipient. The bioavailable composition of curcumin includes a curcuminoid mixture and an added essential oil of turmeric. The curcuminoid mixture includes curcumin, demethoxycurcumin and bisdemethoxycurcumin. The added essential oil of turmeric includes about 40% to about 50% of ar-turmerone. Methods of preparing sustained release compositions having a bioavailable curcumin composition and a release rate controlling excipient.
    Type: Grant
    Filed: July 16, 2015
    Date of Patent: May 14, 2019
    Assignee: ARJUNA NATURAL EXTRACTS, LTD.
    Inventor: Benny Antony
  • Patent number: 10159654
    Abstract: Disclosure provides a formulation of curcuminoid with essential oil of turmeric to enhance the bioavailability of curcumin and to augment the biological activity of curcumin, wherein curcumin is the main constituent of curcuminoid and wherein Ar-turmerone is the main constituent of the essential oil of turmeric. An application of curcuminoid with essential oil of turmeric to enhance the bioavailability of curcumin for oral supplementation against a variety of diseases and method of doing the same is provided.
    Type: Grant
    Filed: September 3, 2014
    Date of Patent: December 25, 2018
    Assignee: ARJUNA NATURAL EXTRACTS, LTD
    Inventor: Benny Antony
  • Patent number: 10086033
    Abstract: The invention relates to a method of treating or preventing pain, or a condition associated with pain, in a subject in need thereof comprising applying topically an effective amount of an extract of Zingiber Officinale (ginger), and to topical compositions and articles of manufacture comprising an extract of Zingiber Officinale.
    Type: Grant
    Filed: December 24, 2014
    Date of Patent: October 2, 2018
    Assignee: INNOVATIVE HERBAL PRODUCTS (AUST) PTY LTD
    Inventors: Michael J. Dale, Gregory J. Dale
  • Patent number: 10086026
    Abstract: An herbal combination composition can include, herbal extracts, including combinations of: Hyssopus officinalis, Zingiber officinale, Viola odorata, Ziziphus jujuba, Chamomile, and Ocimum tenuiflorum; pharmaceutical compositions, including combinations of: dextromethorphan, guaifenesin, acetaminophen, phenylephrine, diphenhydramine; polyethylene glycol; propylene glycol; poloxamer 407; ethylenediaminetetraacetic acid; methyl paraben; potassium sorbate; propyl paraben; xanthan gum; citric acid; anhydrous citric; and purified acetate buffered water. Also disclosed is a method for manufacture of an herbal combination composition, including dissolving herbal extracts, adding poloxamer, adding pharmaceutical compositions, adding acetate buffer, adding xanthan gum gel, adding acetate buffer.
    Type: Grant
    Filed: June 27, 2016
    Date of Patent: October 2, 2018
    Inventor: Uwais M. Syed
  • Patent number: 10080378
    Abstract: The present disclosure provides highly digestible pet food compositions that, when ingested by an animal, result in reduced stool volume, weight, and odor, and methods of use employing those compositions.
    Type: Grant
    Filed: December 19, 2011
    Date of Patent: September 25, 2018
    Assignee: Colgate-Palmolive Company
    Inventors: David Kappelman, Susy Tejayadi, Valerie Proctor
  • Patent number: 9925136
    Abstract: A composition for applying to skin in need of treatment for skin barrier restoration, hydration and moisturization, the composition comprising extracts of Ampelopsis grossedentata and Albizia julibrissin. Also provided are methods for treating skin in need of skin barrier treatment, methods of treating skin to reduce the signs of aging and methods of treating skin to reduce the signs of inflammation with a composition comprising extracts of Ampelopsis grossedentata and Albizia julibrissin.
    Type: Grant
    Filed: September 24, 2015
    Date of Patent: March 27, 2018
    Assignee: Johnson & Johnson Consumer Inc.
    Inventors: Hua Du, Yan Li, Tao Liu, Yingxin Ma
  • Patent number: 9867860
    Abstract: The invention provides formulations to prevent or treat decreasing platelet cell counts. The formulations essentially consist of peanut skins, papaya leaves, folic acid, vitamin B12, vitamin C, vitamin D, vitamin E, selenium, and iron. In some formulations, some vitamins are replaced by fruit or vegetable juice.
    Type: Grant
    Filed: July 8, 2014
    Date of Patent: January 16, 2018
    Inventors: Huihong Qiao, Wenjian Zhang
  • Patent number: 9815770
    Abstract: Compounds that are central nervous system drug candidates for the treatment of cognitive decline and, more particularly, Alzheimer's disease are provided. Methods of treating, inhibiting, and/or abatement of cognitive decline and/or Alzheimer's disease with a compound or pharmaceutically acceptable salt of the invention are also provided. Also provided are methods of preparing the compounds/compositions of the invention.
    Type: Grant
    Filed: October 16, 2015
    Date of Patent: November 14, 2017
    Assignee: Cognition Therapeutics, Inc.
    Inventors: Gilbert M. Rishton, Susan Catalano
  • Patent number: 9789142
    Abstract: The present invention relates to the field of nutraceuticals, and in particular to nutraceuticals comprising sulfated polysaccharides, Astragalus polysaccharides, resveratrol, and combinations thereof. These compositions find use in inducing physiological responses such, decreasing body fat, increasing lean body mass, alleviating the symptoms of colds, preventing the onset of colds, increasing energy, increasing the feeling of well-being in subjects, and improving skin tone and appearance.
    Type: Grant
    Filed: April 1, 2014
    Date of Patent: October 17, 2017
    Assignee: LIFE SCIENCE NUTRITION AS
    Inventor: Jan Remmereit
  • Patent number: 9775875
    Abstract: The invention discloses a method of processing Zingiber zerumbet for producing a processed sample of Zingiber zerumbet, which easily releases flavonoids in a following extraction process. The method includes the steps of: soaking a raw sample of Zingiber zerumbet with a processing reagent selected from rice vinegar or yellow wine at 23-27° C. for 20-28 hours; and steaming the soaked product at 0.6-1.4 kg/cm2, 80-120° C. for 20-40 minutes.
    Type: Grant
    Filed: May 29, 2015
    Date of Patent: October 3, 2017
    Assignee: HAN SHENG PHARMTECH, INC.
    Inventors: Shorong-Shii Liou, I-Min Liu, Cheng Yang, Sheng-Da Lin, Chi-Da Fang, Bo-Wei Lin, Wan-Ling Huang, Ya-Ting Shiu
  • Patent number: 9770479
    Abstract: The present invention relates to a Rehmannia glutinasa Libosch. extract for reducing blood glucose and lipid levels and treating hematologic diseases such as leukemia, and methods for preparing the same. The extract is prepared by subjecting fresh Rehmannia glutinasa Libosch. to flux extraction, concentrating the resultant extract, dissolving the concentrated extract with water, loading the obtained solution on a column packed with macroporous adsorption resins, eluting the column with ethanol, concentrating and drying the eluate. The extract can be made into clinically acceptable forms of dosage by pharmaceutically conventional measures, including capsule, tablet, pill, granule, dropping pill and so on. The extract is stable and has catalpol content up to 90-98%. The preparing method is simple to operate and applicable to industrial-scale production.
    Type: Grant
    Filed: July 27, 2015
    Date of Patent: September 26, 2017
    Inventor: Ling Zhang
  • Patent number: 9737583
    Abstract: The present invention relates to a composition including an Amomi Rotundus Fructus extract or a fraction thereof as an active ingredient, which can be used for the prevention, amelioration, or treatment of acute renal failure.
    Type: Grant
    Filed: November 6, 2013
    Date of Patent: August 22, 2017
    Assignee: KOREA INSTITUTE OF ORIENTAL MEDICINE
    Inventors: Hyun Kyoo Shin, Ju Young Jung, Hye Kyung Ha, Chang Seob Seo, Young Jung Kim
  • Patent number: 9492402
    Abstract: A formulation of curcuminoid mixture having curcumin, demethoxycurcumin and bisdemethoxycurcumin and an essential oil of turmeric having 45% Ar-turmerone. The formulation gives enhanced bioavailability of bisdemethoxycurcumin, demethoxycurcumin and curcumin for up to 10 hrs. The curcuminoid mixture has curcumin, demethoxycurcumin and bisdemethoxycurcumin in a weight/weight ratio ranging from about 0.8:1:1 to about 1:1.1:1.2. A process of preparing a formulation of curcuminoid mixture having curcumin, demethoxycurcumin and bisdemethoxycurcumin in 0.8:1:1 to 1:1:1:1.2 weight/weight ratio and an essential oil of turmeric having 45% Ar-turmerone. A formulation for improved biological activity and bioavailability and tissue distribution of curcumin, demethoxycurcumin and bisdemethoxycurcumin.
    Type: Grant
    Filed: March 12, 2014
    Date of Patent: November 15, 2016
    Inventor: Benny Antony
  • Patent number: 9446085
    Abstract: The present invention discloses an herbal extract of inhibiting fat-storage function of adipocytes. The herbal extract comprises an Acanthopanax senticosus extract, a Zingiber officinale Roscoe extract and a Coix lachryma-jobi L. extract, wherein a weight percentage of the Acanthopanax senticosus extract is 60 to 80% by weight of the herbal extract, wherein a weight percentage of the Zingiber officinale Roscoe extract is 10 to 30% by weight of the herbal extract, wherein a weight percentage of the Coix lachryma-jobi L. extract is 10% by weight of the herbal extract.
    Type: Grant
    Filed: January 23, 2014
    Date of Patent: September 20, 2016
    Assignee: HAN SHENG BIOTECH CO., LTD
    Inventors: Shorong-Shii Liou, I-Min Liu, Chia-Ju Chang
  • Patent number: 9408894
    Abstract: The present invention relates to a food supplement composition for reducing fatigue, and/or improving recovery and resistance to fatigue. The composition comprised of collagen hydrolysate, blueberry extract and liquorice extract.
    Type: Grant
    Filed: August 26, 2013
    Date of Patent: August 9, 2016
    Inventor: Michel Grisé
  • Patent number: 9381221
    Abstract: It is disclosed a phytocomposition which includes: (a) 0.01 wt % to 26 wt % of Arnica montana extract; (b) 0.01 wt % to 26 wt % of Rosmarinus officinalis extract; (c) 0.01 wt % to 26 wt % of Zingiber officinale extract; and (d) 0.01 wt % to 26 wt % of Boswellia serrate extract. Said phytocomposition can be used in combination with a pharmaceutically acceptable carrier in order to obtain a pharmaceutical composition that can be used for treating muscle, arthritic and rheumatic pain in a patient, caused by joint diseases, in particular rheumatoid arthritis, osteoarthritis, fibromyalgia, gouty arthritis, psoriatic arthritis, lupus and juvenile arthritis.
    Type: Grant
    Filed: January 16, 2012
    Date of Patent: July 5, 2016
    Inventor: Héctor de Jesús Vélez-Rivera
  • Patent number: 9283259
    Abstract: Disclosed is a combination of lipophilic extracts of Zingiber officinale and Echinacea angustifolia for the treatment of itching, peripheral pain, superficial and deep inflammatory and painful states, pain associated with muscle spasms, herpes pain, and radiodermatitis caused by oncological radiotherapy, with or without fungal or bacterial infections.
    Type: Grant
    Filed: July 20, 2011
    Date of Patent: March 15, 2016
    Assignee: INDENA S.P.A.
    Inventors: Ezio Bombardelli, Paolo Morazzoni
  • Patent number: 9271493
    Abstract: Compositions and methods for the dissolution of a microbial biofilm are provided, where the method comprises contacting a microbiofilm with an effective dose of a curcumin derivative as a biofilm inhibitor. In some embodiments the curcumin derivative is dimethoxycurcumin. In some embodiments the biofilm comprises E. coli, e.g. including uropathogenic E. coli. The biofilm can be present in vitro or in vivo. The biofilm inhibitor may be administered alone, or in combination with bacteriocidal agents.
    Type: Grant
    Filed: June 19, 2013
    Date of Patent: March 1, 2016
    Assignee: The Board of Trustees of the Leland Stanford Junior University
    Inventors: Lynette Cegelski, Ji Youn Lim
  • Patent number: 9259401
    Abstract: The invention disclosed relates to a water-soluble composition having enhanced bioavailability useful for the treatment of depression which comprises a synergistic combination of curcumin, at least an antioxidant, a hydrophilic carrier and a fat. The invention also discloses a process for the preparation of the curcumin composition which comprises the steps of dissolving curcumin, at least one antioxidant, a hydrophilic carrier and a fat in a solvent to form a homogenous mass; warming the resultant mass at a temperature ranging from 25° C. to 60° C. for a period of 4 to 8 hours to obtain a dry wet mass; removing the solvent by evaporation to form dry mass and pulverizing the dry mass to form a fine powder.
    Type: Grant
    Filed: July 22, 2011
    Date of Patent: February 16, 2016
    Assignee: OMNIACTIVE HEALTH TECHNOLOGIES LTD.
    Inventors: Jayant Venkatesh Deshpande, Shrinivas Krishnarao Kulkarni
  • Patent number: 9161984
    Abstract: This invention relates to a topical gel drug product preparation containing a composition comprising an isolated polypeptide having a carboxy-terminal amino acid sequence of an alpha connexin (ACT peptide), peptide stabilizers, excipients, buffering agents, and the like. A formulation and preparation steps are disclosed for the manufacturing of a stable, elegant, and pourable topical gel. The resulting formulation possesses long term stability suitable for aesthetic as well as therapeutic applications including the prevention of scaring and accelerated healing of wounds. Methods for treatment of chronic wounds, including chronic ulcers, are also provided.
    Type: Grant
    Filed: July 25, 2014
    Date of Patent: October 20, 2015
    Assignee: FIRSTSTRING RESEARCH, INC.
    Inventor: Gautam Ghatnekar
  • Patent number: 9125936
    Abstract: Ginger extract compositions containing 25 to 30% b.w. [6]-gingerol, 5 to 10% b.w. [8]-gingerol, 5 to 10% b.w. [10]-gingerol, 1.5 to 4% b.w. [6]-shogaol, 0.3 to 1.3% b.w. [8]-shogaol, 0.03 to 1% b.w. [10]-shogaol and 0.01 to 1% b.w. zingerone, with the amount of gingerols totaling 35 to 50% b.w. and the amount of shogaols totaling 1.5 to 6% b.w.
    Type: Grant
    Filed: February 20, 2014
    Date of Patent: September 8, 2015
    Assignee: Symrise AG
    Inventors: Imke Meyer, Martina Herrmann, Dominik Stuhlmann, Holger Joppe
  • Patent number: 9089595
    Abstract: The present invention relates to a Rehmannia glutinasa Libosch. extract for reducing blood glucose and lipid levels and treating hematologic diseases such as leukemia, and methods for preparing the same. The extract is prepared by subjecting fresh Rehmannia glutinasa Libosch. to flux extraction, concentrating the resultant extract, dissolving the concentrated extract with water, loading the obtained solution on a column packed with macroporous adsorption resins, eluting the column with ethanol, concentrating and drying the eluate. The extract can be made into clinically acceptable forms of dosage by pharmaceutically conventional measures, including capsule, tablet, pill, granule, dropping pill and so on. The extract is stable and has catalpol content up to 90-98%. The preparing method is simple to operate and applicable to industrial-scale production.
    Type: Grant
    Filed: June 27, 2008
    Date of Patent: July 28, 2015
    Inventor: Ling Zhang
  • Patent number: 9056117
    Abstract: The present invention pertains to a herbal formulation with highly potent wound healing properties, in humans and animals. The composition consists of aqueous extracts of Azadirachta indica, in a mixture of natural oils along with herbs viz. Berberis aristata, Curcuma longa, Glycyrrhiza glabra, Jasminum officinale, Picrorhiza kurrooa, Pongamia pinnata, Rubia folia, Saussurea lappa, Terminalia chebula, Trichosanthes dioica, Capsicum and Stellata wild in well-defined ratios. The invention also includes a process for preparing the formulation by extracting the water-soluble components from bark of Azadirachta indica.
    Type: Grant
    Filed: November 28, 2007
    Date of Patent: June 16, 2015
    Assignee: SUNEV PHARMA SOLUTIONS LTD.
    Inventor: Manish Saxena
  • Publication number: 20150132280
    Abstract: A human dietary supplement comprises theacrine and optionally other compounds that modulate the effects of theacrine. Uses for the theacrine-containing supplement include improvement of at least one of mood, energy, focus, concentration or sexual desire or a reduction of at least one of anxiety or fatigue.
    Type: Application
    Filed: November 12, 2014
    Publication date: May 14, 2015
    Applicant: ORTHO-NUTRA, LLC
    Inventors: Hector L Lopez, Shawn Wells, Tim N. Ziegenfuss
  • Patent number: 9028888
    Abstract: Disclosed herein are compositions and methods for the treatment and management of pain in a subject comprising or consisting of topically or orally administering a therapeutic effective amount of a composition. The composition is made up of minute amounts of herbal extracts and compound mixtures to a subject. The composition includes turmeric extract, Boswellia extract, ginger extract, holy basil extract, rosemary extract, white willow extract and alpha lipolic acid each in minute amounts.
    Type: Grant
    Filed: June 6, 2013
    Date of Patent: May 12, 2015
    Inventor: Reza Ghorbani
  • Patent number: 9023407
    Abstract: The present invention relates to a plant extract for treating diabetes and a process for making same. The plant extract of the invention is prepared from an overground part of Hedychium coronarium Koenig, which has the efficacies of lowering blood glucose, increasing insulin levels, reducing insulin resistance and treating and/or preventing diabetes without overly reducing blood glucose in a subject, i.e., not reducing blood glucose in a fasting subject. Also provided herein is a method for treating diabetes in a subject in need thereof comprising administering an effective amount of the plant extract to the subject.
    Type: Grant
    Filed: August 8, 2012
    Date of Patent: May 5, 2015
    Assignee: Development Center for Biotechnology
    Inventors: Rey-Yuh Wu, Hui-Ling Chen, Yu-Yuan Wu, Lung-Yu Kuan, Chao-Tsen Lu, Shoei-Sheng Lee