Containing Or Obtained From Leguminosae (e.g., Legumes Such As Soybean, Kidney Bean, Pea, Lentil, Licorice, Etc.) Patents (Class 424/757)
  • Patent number: 10307451
    Abstract: The present invention provides compositions comprising optimized ratios of Red clover phytoestrogens as determined by a proprietary physiologically based pharmacokinetic and pharmacodynamic model. The compositions are useful for modulating, preventing or treating postmenopausal or climacteric symptoms, which include but are not limited to bone loss, bone remodeling, hot flushes and vaginal atrophy. The present invention also provides methods for modulating, preventing or treating postmenopausal or climacteric symptoms using the compositions disclosed herein.
    Type: Grant
    Filed: May 9, 2016
    Date of Patent: June 4, 2019
    Assignee: SINOVEDA CANADA INC.
    Inventors: Yun Kau Tam, Yi-Chan James Lin, Brian Duff Sloley, Chih-Yuan Tseng
  • Patent number: 10286024
    Abstract: An excipient from Trigonella foenum-graceum seeds and a process for preparation thereof is disclosed. The excipient obtained from Trigonella foenum-graceum seeds, comprising insoluble and soluble dietary fibers can be used in various pharmaceutical or cosmetic compositions and food, nutritional or dietary preparations.
    Type: Grant
    Filed: April 6, 2011
    Date of Patent: May 14, 2019
    Assignee: RUBICON RESEARCH PRIVATE LIMITED
    Inventors: Pratibha Sudhir Pilgaonkar, Maharukh Tehmasp Rustomjee, Anilkumar Surendrakumar Gandhi
  • Patent number: 10238744
    Abstract: The present invention relates to the field of carrier and delivery systems for active molecular compounds. In particular, the present invention provides aqueous dispersions for delivery of active molecular compounds.
    Type: Grant
    Filed: August 28, 2017
    Date of Patent: March 26, 2019
    Assignee: AUSTIN RESEARCH LABS CORP.
    Inventors: Jai Supamahitorn, Lauren McMillan
  • Patent number: 10226422
    Abstract: The invention provides a beverage composition comprising hydrolyzed collagen and vitamin C, or a derivative thereof, which is particularly suitable for improving skin hydration and skin condition. Additional active ingredients may include methyl sulphonyl methane, a vitamin selected from the vitamin B complex, L-lysine, omega-3 and omega-6 fatty acids. The beverage composition is such that it promotes higher absorption and bioavailability of skin-nourishing ingredients. The beverage composition can improve the moisture content of the skin and can prevent fine lines and wrinkles.
    Type: Grant
    Filed: January 23, 2014
    Date of Patent: March 12, 2019
    Assignee: BOTTLED SCIENCE LIMITED
    Inventors: Piers Raper, Christiaan Haig, Obi Ejifor, Richard Raper
  • Patent number: 10223500
    Abstract: The present invention provides methods, systems and devices for drug-drug interaction and adverse event analysis. Chemical structures for one or more pairs of drugs are obtained from at least one of a user and a database. A chemical fingerprint is generated for each drug of the one or more pairs of drugs based on the chemical structure of the drug. Drug-drug interaction prediction is performed for each pair of drugs based on the chemical fingerprints. Adverse event prediction is performed based on the predicted drug-drug interaction for the one or more pairs of drugs.
    Type: Grant
    Filed: December 21, 2015
    Date of Patent: March 5, 2019
    Assignee: International Business Machines Corporation
    Inventors: Jianying Hu, Yashu Liu, Ping Zhang
  • Patent number: 10166237
    Abstract: The present invention provides compounds and compositions for the amelioration of arthritis and joint injuries by inducing mesenchymal stem cells into chondrocytes.
    Type: Grant
    Filed: September 2, 2016
    Date of Patent: January 1, 2019
    Assignee: The Scripps Research Institute
    Inventors: Peter Schultz, Laure Bouchez
  • Patent number: 10149878
    Abstract: The invention is a method of enhancing female libido by administering an effective amount of a fenugreek extract, for example fenugreek seed extract, to a female in need of enhanced libido. The female can be a human female.
    Type: Grant
    Filed: December 5, 2013
    Date of Patent: December 11, 2018
    Assignee: GE Nutrients, Inc.
    Inventors: Sunil Bhaskaran, Ramasamy V. Venkatesh, Jith Veeravalli
  • Patent number: 10111920
    Abstract: Provided are: a production method for salt-free miso, in which steamed soy beans and koji are pressurized, heated, and fermented; salt-free miso obtained by said production method; and a hepatic function improvement agent and a hypertension improvement agent that contain said salt-free miso as an effective component thereof.
    Type: Grant
    Filed: January 6, 2015
    Date of Patent: October 30, 2018
    Assignees: MARUZEN PHARMACEUTICALS CO., LTD., MASUYAMISO CO., LTD.
    Inventors: Tatsuo Nakahara, Takashi Kawano
  • Patent number: 10111825
    Abstract: Disclosed is a composition in the form of an oil-in-water emulsion, including: 5-55 wt % of an oil phase; 0.025-3.75 wt % of at least one cross-linked anionic polyelectrolyte resulting from the polymerization of partially or completely salified 2-methyl 2-[(1-oxo 2-propenyl) amino] 1-propanesulfonic acid, with at least one neutral monomer selected from acrylamide, (2-hydroxy ethyl) acrylate, and N,N-dialkyl arylamides. Each alkyl group includes 1-4 carbon atoms, and at least one monomer, where R is an alkyl radical including 8-20 carbon atoms and n is a number no smaller than one and no larger than twenty, in the presence of a cross-linking agent; 0.025-3.75 wt % of a galactomannan having a degree of substitution of approximately 1/3; 37.5-94.95 wt % of a cosmetically acceptable aqueous phase, the aqueous phase including 1-25 wt % of a salt, the weight ratio between the galactomannan and the cross-linked anionic polyelectrolyte being 1:3 to 3:1.
    Type: Grant
    Filed: December 5, 2012
    Date of Patent: October 30, 2018
    Assignee: SOCIETE D'EXPLOITATION DE PRODUITS POUR LES INDUSTRIES CHIMIQUES SEPPIC
    Inventor: Emmanuelle Merat
  • Patent number: 10086017
    Abstract: A wound dressing makes use of polysaccharides, including the formation of a range of variable viscosity mixtures that use a solid polysaccharide such as medical grade cane sugar and a liquid polysaccharide such as honey, both of which have inherent beneficial properties for wound healing. The mixture is applied to an absorbent surface that is designed to absorb the mixed polysaccharide only partially.
    Type: Grant
    Filed: September 19, 2013
    Date of Patent: October 2, 2018
    Assignee: Medline Industries, Inc.
    Inventors: Debashish Chakravarthy, Andrew J. Ford
  • Patent number: 9943560
    Abstract: The invention provides drug compositions with synergistic effects, which includes alcohol-soluble and water-insoluble liquorices extracts and at least one kind of anti-tumor or glucose-and-lipid-lowering drug/eatable substance, and can be used to treat tumor or lower blood glucose and lipid. Besides, the invention also provides pharmaceutical preparation, pharmaceutical application, therapeutic and preparation methods, etc. related to this drug compositon.
    Type: Grant
    Filed: January 26, 2011
    Date of Patent: April 17, 2018
    Inventors: James Zhou, Dong Chen
  • Patent number: 9775856
    Abstract: The present invention concerns the antidiabetic-activity of compounds type A, namely of 8-?-D-glucosylgenistein, which is not toxic to eukaryotic cells and has demonstrated to produce complete normalization of fasting hyperglycaemia, to reduce excessive postprandial glucose excursion, to increase glucose-induced insulin secretion and insulin sensitivity. An alternative synthesis for this molecular entity and its binding ability to ?-amyloid oligomers is also included in the present invention, which also comprises Genista tenera ethyl acetate extract for use as antihyperglycaemic, agent i.e. for lowering blood glucose levels in mammals that are pre-diabetic or have type 2 or type 1 diabetes. The inhibitory activity of ?-glucosidase by Genista tenera ethyl acetate and butanol extracts and that of glucose-6-phosphatase by these two extracts and the diethyl ether plant extract is also part of the present invention.
    Type: Grant
    Filed: March 11, 2013
    Date of Patent: October 3, 2017
    Assignee: FACULDADE DE CIENCIAS DA UNIVERSIDADE DE LISBOA
    Inventors: Amélia Pilar Grases Santos Silva Rauter, Ana Rita Xavier De Jesus, Alice Isabel Mendes Martins, Catarina Alexandra Dos Santos Dias, Rogério José Tavares Ribeiro, Maria Paula Borges De Lemos Macedo, Jorge Alberto Guerra Justino, Helder Dias Mota Filipe, Rui Manuel Amaro Pinto, Bruno Miguel Nogueira Sepodes, Margarida Alexandra Patrício Goulart De Medeiros, Jesus Jimenéz Barbero, Cristina Airoldi, Francesco Nicotra
  • Patent number: 9775874
    Abstract: In a new supplemental combination and method of treatment, the herbs Vitex agnus-castus (chasteberry), green tea, and arginine treat premenstrual syndrome, premenstrual tension, as an alternative to conventional women's hormone replacement therapy, and to offset the problems related to sub-optimal hormone balance or decline resulting from age, genetics, stress, or environmental influences. Furthermore, the combination may be enhanced with a phytoestrogen and/or a progesterone-receptor enhancing agent.
    Type: Grant
    Filed: September 30, 2013
    Date of Patent: October 3, 2017
    Assignee: The Daily Wellness Company
    Inventor: Denny W. Kwock
  • Patent number: 9744238
    Abstract: The present invention relates to the field of carrier and delivery systems for active molecular compounds. In particular, the present invention provides aqueous dispersions for delivery of active molecular compounds.
    Type: Grant
    Filed: September 15, 2015
    Date of Patent: August 29, 2017
    Assignee: AUSTIN RESEARCH LABS CORP.
    Inventors: Jai Supamahitorn, Lauren McMillan
  • Patent number: 9649351
    Abstract: Disclosed herein are an anti-obesity agent from natural products based on angiogenesis inhibitory actions, and an angiogenesis inhibitor or a composition for inhibiting obesity, containing at least one selected from the group consisting of Psoraleae Semen extract, Siegesbeckiae Herba extract, and Corni Fructus extract. Because the Psoraleae Semen extract, Siegesbeckiae Herba extract, and Corni Fructus extract of the present invention exhibit angiogenesis inhibitory effects and obesity inhibitory effects, they may be usefully used as an agent for prevention and treatment of angiogenesis-related diseases or obesity.
    Type: Grant
    Filed: April 30, 2014
    Date of Patent: May 16, 2017
    Assignee: Industry Foundation of Chonnam National University
    Inventor: Jong-Deog Kim
  • Patent number: 9642357
    Abstract: To provide an oil-based pesticidal suspension which suppresses foaming at the time of preparation of a spray liquid by an organic silicone type surfactant, and which has excellent pesticidal activity with a small amount of an agricultural chemical. The present invention provides an oil-based pesticidal suspension comprising (1) flonicamid or its salt, (2) an organic silicone type surfactant and (3) at least one oil-based diluting agent selected from the group consisting of a vegetable oil and its alkylated oil, and a method for controlling pests, which comprises applying the oil-based pesticidal suspension to the pests or to a place where they grow.
    Type: Grant
    Filed: December 5, 2013
    Date of Patent: May 9, 2017
    Assignee: ISHIHARA SANGYO KAISHA, LTD.
    Inventors: Mitsuo Sano, Takashi Okada, Yasuhiro Okumura, Mitsugu Iwasa, Yusuke Kobayashi
  • Patent number: 9629786
    Abstract: The present invention relates to new monoterpene derivatives of chalcone or dihydrochalcone and their use as a depigmenting agent.
    Type: Grant
    Filed: January 18, 2012
    Date of Patent: April 25, 2017
    Assignee: PIERRE FABRE DERMO-COSMETIQUE
    Inventors: Anne Mandeau, Stéphane Poigny, Françoise Belaubre
  • Patent number: 9572765
    Abstract: Disclosed is a composition for preventing hair loss or promoting hair restoration and for enhancing hair health, the composition comprising an active ingredient in the form of soy extract extracted using a C1 to C5 alcohol at a concentration of between 1% and 70% (v/v).
    Type: Grant
    Filed: June 11, 2012
    Date of Patent: February 21, 2017
    Assignee: AMOREPACIFIC CORPORATION
    Inventors: Hee Young Jeon, Seung Hun Kim, Su Kyung Kim, Hyun Jung Shin, Dae Bang Seo
  • Patent number: 9511013
    Abstract: This invention provides a Chinese medicinal formula comprising Atractylodis Macrocephalae Rhizoma, Glycyrrhizae Radix et Rhizoma, Angelicae sinensis Radix, Paeoniae Radix Alba and Poria for skin care. It further relates to a method for preparing bioactive fraction of this formula and to the applications of the bioactive fraction in skin-whitening and anti-skin-aging.
    Type: Grant
    Filed: February 27, 2014
    Date of Patent: December 6, 2016
    Assignee: Hong Kong Baptist University
    Inventors: Zhiling Yu, Hua Yu
  • Patent number: 9504724
    Abstract: The present invention relates to a pharmaceutical composition containing Puerariae Flos extracts as active ingredients for preventing or treating endometriosis and the complications thereof. More particularly, Puerariae Flos extracts exhibit the activity of inhibiting the migration and adhesion of endometriosis cells, inhibiting the expressions of MMP-2 and MMP-9, which are factors associated with migration and adhesion, inhibiting the expression of COX-2, which is a factor associated with pain, and inhibiting the expression of MCP-1, which is a cytokine associated with inflammation, and RANTES. Therefore, the Puerariae Flos extracts of the present invention can be effectively used as active ingredients for a pharmaceutical composition for preventing and treating endometriosis and the complications thereof, and for a health food.
    Type: Grant
    Filed: September 24, 2012
    Date of Patent: November 29, 2016
    Assignee: University-Industry Cooperation Group of Kyung-Hee University
    Inventors: Jung-Hye Choi, Ji-Hyyun Kim
  • Patent number: 9499508
    Abstract: The present invention relates to the use of compounds of the formula (I) for the care, preservation or improvement of the general condition or appearance of the skin or hair, and to preparations comprising compounds of the formula (I).
    Type: Grant
    Filed: November 14, 2011
    Date of Patent: November 22, 2016
    Assignee: MERCK PATENT GMBH
    Inventors: Christophe Carola, Tatjana Mueller
  • Patent number: 9464065
    Abstract: The present invention provides compounds and compositions for the amelioration of arthritis and joint injuries by inducing mesenchymal stem cells into chondrocytes.
    Type: Grant
    Filed: March 26, 2012
    Date of Patent: October 11, 2016
    Assignee: The Scripps Research Institute
    Inventors: Peter Schultz, Laure Bouchez
  • Patent number: 9445605
    Abstract: Provided herein is a method for disinfection or infection control against a non-enveloped virus using a composition including, as an active ingredient, a persimmon extract containing tannin from an astringent fruit of a plant of the genus Diospyros, such as the plant Diospyros kaki. The non-enveloped virus is a non-enveloped virus belonging to the genus Betanodavirus, Aquavirnavirus, Ranavirus, Enterovirus, Mastadenovirus, Vesivirus, or Rotavirus. In certain embodiments, the persimmon extract is prepared by heating a squeezed juice or an extract from an astringent fruit of a plant of the genus Diospyros, or obtained by treating a squeezed juice or an extract from an astringent fruit of the plant of the genus Diospyros with an alcohol, in order to inactivate an enzyme contained therein. The persimmon extract may also contain at least condensed tannin.
    Type: Grant
    Filed: July 11, 2013
    Date of Patent: September 20, 2016
    Assignees: Hiroshima University, Altan Co., Ltd.
    Inventors: Tadashi Shimamoto, Yasushi Okinaka, Takemasa Sakaguchi, Toru Tsuji, Yoshiaki Nakai
  • Patent number: 9421234
    Abstract: Methods comprising administration of: (i) avocado/soybean unsaponifiables and (ii) lipoic acid or derivatives thereof, to a mammalian or an avian subject are provided. This invention also relates to orally administrable compositions comprising avocado/soybean unsaponifiables and lipoic acid or derivatives thereof.
    Type: Grant
    Filed: May 20, 2011
    Date of Patent: August 23, 2016
    Assignee: NUTRAMAX LABORATORIES, INC.
    Inventors: Carmelita Frondoza, Todd R. Henderson, Reinhard Grzanna
  • Patent number: 9381222
    Abstract: The present invention relates to compositions for preventing and treating obesity, hyperlipidemia, atherosclerosis, fatty liver, diabetes or metabolic syndrome containing extracts of Glycine max leaves or fractions isolated from the same.
    Type: Grant
    Filed: November 10, 2009
    Date of Patent: July 5, 2016
    Assignee: Korea Reasearch Institute of Bioscience and Biotechnology
    Inventors: Tae-Sook Jeong, Woo Song Lee, Ki Hun Park, Myung-Sook Choi, Ho Yong Park, Jong-Min Han, Hyung-Jae Jeong
  • Patent number: 9301987
    Abstract: Herbal compositions are useful for inhibition, amelioration or prevention of adipogenesis mediated diseases such as obesity, lipid storage disease and hyperlipemia. The herbal compositions comprise biologically effective amounts of extracts or fractions from Piper betle in combination with one or more of the extracts or fractions derived from Dolichos biflorus, Commiphora mukul, Boerhaavia diffusa, Tribulus terrestris and Zingiber officinale as active ingredients. The compositions optionally contain a bio-enhancing agent or a bio-protecting agent, along with biologically acceptable carriers or diluents. The herbal compositions may be used in a method for treating or preventing adipogenesis involved diseases in mammals.
    Type: Grant
    Filed: September 24, 2007
    Date of Patent: April 5, 2016
    Assignee: LAILA NUTRACEUTICALS
    Inventors: Ganga Raju Gokaraju, Rama Raju Gokaraju, Trimurtulu Golakoti, Krishanu Sengupta, Kiran Bhupathiraju, Venkata Krishna Raju Alluri
  • Patent number: 9272011
    Abstract: A pharmaceutical composition for treating urinary incontinence and/or enuresis, which comprises at least 0.5-20 wt % of a mixture of flavonoids, 2-20 wt % of condensed tannins or proantocyanidins and 0.3-60 wt % of gamma aminobutyric acid (GABA), with respect to the total composition. The composition additionally comprises at least 50% of a Humulus lupulus extract. The composition is used for preparing a medicine for treating incontinence and/or enuresis, in particular enuresis in children, as well as in adults or the elderly who have urine leaks such as incontinence due to stress or urgency.
    Type: Grant
    Filed: January 22, 2013
    Date of Patent: March 1, 2016
    Assignee: LABORATEC, S.L.
    Inventor: Juan Carlos Llobregat Agusti
  • Patent number: 9265810
    Abstract: This invention provides a pharmaceutical composition for modulating immune system comprising at least one polysaccharide extracted from Radix Astragali, Radix Codonopsis, Ganoderma sinense, or mixtures thereof, and their extraction process. The present invention further relates to a method of modulating immune system by applying said pharmaceutical composition to a subject suffering from cancers, and a method of preventing and/or pretreating and/or treating cancers in the subject, where said method comprises applying said pharmaceutical composition before/during chemotherapy.
    Type: Grant
    Filed: March 13, 2015
    Date of Patent: February 23, 2016
    Assignee: HONG KONG BAPTIST UNIVERSITY
    Inventor: Quanbin Han
  • Patent number: 9259450
    Abstract: The present invention relates to use of a fermented soy extract as a prebiotic composition to protect beneficial bacteria in the gastrointestinal tract of an animal. Particularly, the fermented soy extract of the invention exhibits the prebiotic activity even under an antibiotic treatment. Also disclosed is combined use of an antibiotic and the fermented soy extract of the invention, which has advantages over administration of the antibiotic alone, such as decreasing the effective dose of the antibiotic and/or reducing side effects resulting from the antibiotic treatment.
    Type: Grant
    Filed: July 20, 2011
    Date of Patent: February 16, 2016
    Assignee: MICROBIO CO., LTD.
    Inventors: Ming-Hong Chuang, Cheng Der Tony Yu, Kung-Ming Lu
  • Patent number: 9259024
    Abstract: Compositions and methods relating to high caloric enteral formulations are disclosed herein. The invention provides a dietary composition comprising hydrolyzed soy protein and having a low viscosity and acceptable shelf life. Methods of using the dietary compositions of the invention are also disclosed.
    Type: Grant
    Filed: October 12, 2009
    Date of Patent: February 16, 2016
    Assignee: SOLAE LLC
    Inventors: Yadilka Maldonado, William C. Smith, Minhthy Nguyen
  • Patent number: 9245226
    Abstract: A computerized method for detecting a change point in a data stream by testing whether two sets of samples from the data stream were derived from the same distribution, wherein the test uses the unique convergence properties of the two sample tests to probabilistically find the point which maximizes their value, said point closely approximating the change point.
    Type: Grant
    Filed: September 27, 2011
    Date of Patent: January 26, 2016
    Assignee: CARMEL-HAIFA UNIVERSITY ECONOMIC CORPORATION LTD
    Inventors: Ran Wolff, Murad Badarna
  • Patent number: 9180153
    Abstract: The present invention relates to an extract isolated from Sophorae Radix useful for prevention and treatment of respiratory diseases. More specifically, the present invention relates to a pharmaceutical drug comprising the Sophorae Radix extract having excellent effects of inhibiting airway contraction, respiratory infections, 5-lipoxygenase activity, phosphodiesterase 4 activity, airway hyper-responsiveness and airway remodeling; antagonistic activity against leukotriene D4; and an antitussive effect, thus being useful for prevention and treatment of respiratory diseases such as asthma, acute or chronic bronchitis, allergic rhinitis, acute upper respiratory infections and acute lower respiratory infections, and the like.
    Type: Grant
    Filed: May 12, 2010
    Date of Patent: November 10, 2015
    Assignee: SK Chemicals Co., Ltd.
    Inventors: Chang-Kyun Han, Kiwon Joung, Hunseung Yoo, Yong-Baik Cho, Keun Ho Ryu, Hye Yeon Baek, Taek-Soo Kim, In Ho Jung, Wie-Jong Kwak
  • Patent number: 9167842
    Abstract: The invention concerns a functional food preparation based on milk/dairy products added with botanical products containing various active principles. The milk/dairy products, which can be obtained from fresh or pasteurized animal milk, soy milk or rice milk, comprise Saccharum officinarum containing polycosanols, Monascus purpureus containing plant statins, and Glycine max containing isoflavones and coenzymes. Further components can be added to the preparation to improve its organoleptic properties. The invention also refers to the use of the preparation as a food with functional features which are useful to stabilize the cholesterol and triglycerides amount, having an antioxidant action and protective of arteries and the cardiocirculatory system.
    Type: Grant
    Filed: December 15, 2011
    Date of Patent: October 27, 2015
    Inventor: Guglielmo Buonamici
  • Patent number: 9149062
    Abstract: Compositions for preventing or treating kidney disease comprising one or more food ingredients containing relatively low amounts of protein, sodium, and potassium, typically protein in amounts of from about 5% to about 40%, sodium in amounts of from about 0.01% to about 1%, and potassium in amounts of from about 0.01% to about 1%, and methods comprising administering such compositions to patients susceptible to or suffering from kidney disease for the purpose of preventing or treating kidney disease.
    Type: Grant
    Filed: June 29, 2006
    Date of Patent: October 6, 2015
    Assignee: Hill's Pet Nutrition, Inc.
    Inventors: Kim Gene Friesen, Ryan Michael Yamka
  • Patent number: 9149469
    Abstract: The present invention relates to a pharmaceutical composition having dopaminergic activity and other related pharmaceutical activities comprising trigonelline or its derivative(s) and 4-hydroxyisoleucine or its derivative(s), optionally along with excipients(s); a process of preparing a pharmaceutical composition comprising trigonelline or its derivative(s) and 4-hydroxyisoleucine or its derivative(s), optionally along with excipients(s), wherein the process comprising steps of: (a) extracting a clear solution containing trigonelline and 4-hydroxyisoleucine from plant source; and (b) optionally precipitating derivative(s) of trigonelline and 4-hydroxyisoleucine from the clear solution and obtaining said composition; and an in-vitro method to increase levels of dopamine or to inhibit prolactin by allowing composition comprising trigonelline or its derivative(s) and 4-hydroxyisoleucine or its derivative(s) to bind to cell receptors.
    Type: Grant
    Filed: December 12, 2013
    Date of Patent: October 6, 2015
    Assignee: Indus Biotech Pvt. Ltd.
    Inventors: Sunil Bhaskaran, Mohan Vishwaraman
  • Patent number: 9125877
    Abstract: The invention relates the pharmaceutical use of kaurene compounds of formula (1) in treating and preventing coronary disease, stroke, cerebral ischemia and arrhythmia etc. The said compounds also have significant protecting effects against cerebral ischemic infarction. Wherein R1: hydrogen, hydroxyl or alkoxy R2: carboxyl, carboxylate, acyl halides, aldehyde, methylhydroxyl, and ester, acylamide, acyl or ether group hydrolysable to carboxyl. R3, R4, R5, R6, R8: independently, oxygen, hydroxyl, methylhydroxyl, and ester or alkyloxymethyl group hydrolysable to methylhydroxyl, R7: methyl, hydroxyl, and ester or alkyloxymethyl hydrolysable to methylhydroxyl, R9: methylene or oxygen.
    Type: Grant
    Filed: May 19, 2004
    Date of Patent: September 8, 2015
    Inventor: Wen Tan
  • Patent number: 9049823
    Abstract: The invention overcomes the deficiencies of the art by providing a soybean plant with non-transgenic mutations conferring decreased ?-subunit of ?-conglycinin content and increased ??-subunit content of ?-conglycinin in seed. Moreover, the invention provides an agronomically elite soybean plant with non-transgenic mutations conferring a gyclinin null phenotype, increased ?-conglycinin content, and increased ??-subunit content of ?-conglycinin in the seed. The invention also provides derivatives, and plant parts of these plants and uses thereof. Methods for producing such plants are also provided.
    Type: Grant
    Filed: August 27, 2008
    Date of Patent: June 9, 2015
    Assignee: Monsanto Technology LLC
    Inventors: Neal Bringe, Jonathan Jenkinson
  • Patent number: 9040102
    Abstract: This disclosure relates to a composition for prevention or treatment of neurodegenerative disease comprising longan arillus extract, or combined extract comprising longan arillus. The composition exhibits remarkably excellent prevention or treatment effect of neurodegenerative disease by containing longan arillus extract or combined extract comprising longan arillus, and particularly, it may effectively prevent or treat neurodegenerative disease by significantly protecting dopaminergic neurons from neurotoxicity due to MPTP selectively acting on dopaminergic nervous system and neurotoxicity due to aggregation of alpha-synuclein proteins.
    Type: Grant
    Filed: February 22, 2011
    Date of Patent: May 26, 2015
    Assignee: KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY
    Inventors: Hyun-Ok Yang, Na-Young Bae, Hak-Cheol Kwon, Sung-Kwon Chung, Myung-Sook Oh
  • Publication number: 20150140136
    Abstract: Pesticidal compositions containing plant essential oils, such as rosemary oil, wintergreen oil, etc., and methods for using same are disclosed.
    Type: Application
    Filed: June 19, 2014
    Publication date: May 21, 2015
    Inventors: Steven M. BESSETTE, A. David LINDSAY
  • Publication number: 20150140141
    Abstract: The present disclosure relates to methods for extraction of biomass. Biomass of most interest is that which contains biologically active, extracts suitable for the skin care market. The biomass of interest includes botanicals (plant extracts and bioferments thereof), algae (red, brown, green and red, including bioferments thereof), fungi and even animal extracts (insect, crustacean) origin. Further the use of said extracts in cosmetic preparations prepared by the disclosed method is envisioned.
    Type: Application
    Filed: June 6, 2013
    Publication date: May 21, 2015
    Applicants: BASF BEAUTY CARE SOLUTIONS FRANCE SAS, BASF CORPORATION
    Inventors: Clifford A. Milow, Laurent Bailly, Christopher Judd, Nicole Jeannine Richter
  • Publication number: 20150132280
    Abstract: A human dietary supplement comprises theacrine and optionally other compounds that modulate the effects of theacrine. Uses for the theacrine-containing supplement include improvement of at least one of mood, energy, focus, concentration or sexual desire or a reduction of at least one of anxiety or fatigue.
    Type: Application
    Filed: November 12, 2014
    Publication date: May 14, 2015
    Applicant: ORTHO-NUTRA, LLC
    Inventors: Hector L Lopez, Shawn Wells, Tim N. Ziegenfuss
  • Publication number: 20150132416
    Abstract: The present invention comprises mixtures of herb extracts which exert synergistic antioxidant effect and comprise the herb sophora and kudzu. Skin care preparations incorporating such herb extract mixtures, and their methods of preparation and use, are also claimed.
    Type: Application
    Filed: January 14, 2015
    Publication date: May 14, 2015
    Inventors: Haiyan Ge, Earl Philip Seitz, JR., Thomas Doering
  • Publication number: 20150132415
    Abstract: The present invention provides a pharmaceutical composition or a cosmetic product which can accelerate production of ceramide in cells. The ceramide production-accelerating agent contains a plant selected from the group consisting of Radix Heraclei Scabridi, Rhizoma Dioscoreae, Radix Rehmanniae, Rhizoma Atractylodis Macrocephalae, Radix Glycyrrhizae, Radix Et Rhizoma Rhei, Pseudobulbus Bletillae, Radix Polygoni Multiflori, Radix Platycodi, and Herba Leonuli, or an extract thereof as an active ingredient. Further, the present invention provides a moisturizing agent containing a plant selected from the group consisting of Herba Leonuri and Rhizoma Dioscoreae, or an extract thereof as an active ingredient.
    Type: Application
    Filed: January 20, 2015
    Publication date: May 14, 2015
    Applicants: Zhongshan Hospital of Fudan University, Kao Corporation
    Inventors: Wan Zhang QIN, Chun Xin Yang, Fan Qi Kong, Hiroshi Nojiri, Shotaro Ito
  • Publication number: 20150132417
    Abstract: The present invention comprises mixtures of herb extracts which exert synergistic antioxidant effect and comprise the herb sophora and licorice. Skin care preparations incorporating such herb extract mixtures, and their methods of preparation and use, are also claimed.
    Type: Application
    Filed: January 14, 2015
    Publication date: May 14, 2015
    Inventors: Haiyan Ge, Earl Philip Seitz, JR., Thomas Doering
  • Patent number: 9028885
    Abstract: Disclosed is a composition comprising an extract of at least one selected from a group consisting of Rehmannia glutinosa, licorice, Coicis Semen, Hordei Fructus, Chaenomelis Fructus, Acanthopanacis Cortex and Puerariae Radix as an active ingredient. The composition promotes adipocyte differentiation and lipid droplet formation and is effective in improving skin wrinkles, enhancing skin elasticity and preventing skin aging.
    Type: Grant
    Filed: June 30, 2010
    Date of Patent: May 12, 2015
    Assignee: Amorepacific Corporation
    Inventors: Ji Seong Kim, Ga Young Cho, Eun Joo Kim, Jun Seong Park, Ho Sik Rho, Hye Yoon Park, Duck Hee Kim, Han Kon Kim
  • Patent number: 9028889
    Abstract: The present invention relates to the use of a composition comprising at least one peptidic fava bean extract as an active agent capable of limiting hair loss, and/or stimulating its growth. Moreover, the composition is intended, on one hand, to modulate the Clock, Perl and Bmal1 genes in the dermal papilla cells, and, on the other hand, to restore the circadian rhythm and resynchronize the biological clock of said cells. Finally, the present invention relates to several methods of non-therapeutic cosmetic treatment using said composition.
    Type: Grant
    Filed: July 18, 2011
    Date of Patent: May 12, 2015
    Assignee: ISP Investments Inc.
    Inventors: Claude Dal Farra, Nouha Domloge, Jean-Marie Botto
  • Publication number: 20150125542
    Abstract: A Tie2 activator containing, as an active ingredient, a hawthorn extract, a starfruit extract, a shellflower extract, a lotus extract, a rooibos extract, an Indian date extract, a Chinese quince extract, a Psidium guava extract, a long pepper extract, a Quillaja extract, a Kouki extract, a ginkgo extract, an oyster extract, a turmeric extract, a chrysanthemum extract, a jujube extract, a Chinese wolfberry extract, a chamomile extract, or a Butcher's Broom extract, or any combination thereof.
    Type: Application
    Filed: January 13, 2015
    Publication date: May 7, 2015
    Inventors: Nobuaki OHTO, Akinori KISO
  • Publication number: 20150125410
    Abstract: A hyaluronic acid production promoter and a melanin synthesis inhibitor include soybean saponin as an active ingredient. The soybean saponin can be a soybean saponin aglycone, such as soyasapogenol A and/or soyasapogenol B. The hyaluronic acid production promoter and melanin synthesis inhibitor can be administered transdermally or orally.
    Type: Application
    Filed: January 9, 2015
    Publication date: May 7, 2015
    Inventors: Shuichi KAMO, Shunsuke SUZUKI, Toshiro SATO
  • Publication number: 20150118336
    Abstract: The present invention relates to a functional engineered rice having alcoholism relief and liver protection functions for those drinking alcohol over an extended period of time or drinking alcohol excessively, and preparation method thereof. The engineered rice comprises six starting materials: coarse rice powder, isolated soy protein, kudzu root extract, corn oligopeptide, purple sweet potato powder, and hawthorn extract, and is prepared by: premixing the starting materials; employing a double screw extruder to conduct texturized processing and forming under high temperature and high pressure; and then drying, dedusting and packaging.
    Type: Application
    Filed: October 31, 2014
    Publication date: April 30, 2015
    Inventors: Shenglin Duan, Muyi CAI, Zhe DONG, Yanqiao LIU, Xue WANG, Shiwei LIU, Jie LIU, Ruilian HU, Zian LI
  • Patent number: 9017741
    Abstract: The present invention relates to a water-soluble defructosylated pea extract, substantially free of proteins and peptides, as well as to an oligosaccharide composition such as that contained in said extract. It also relates to the method for preparing the same, and to the use thereof as a prebiotic agent.
    Type: Grant
    Filed: March 22, 2010
    Date of Patent: April 28, 2015
    Assignee: Olygose
    Inventor: François Delbaere