Abstract: Compositions and methods for protecting bees from toxins and for preventing or decreasing colony collapse are provided. The compositions comprise carbon microparticles which, when ingested by bees, increase their survival after exposure to toxins such as pesticides.

Abstract: Disclosed is a detection method for quality grade of traditional Chinese medicine (TCM), including: detecting the levels of quality control index components of TCM and efficacy-related in vitro activity by establishing a correlation between principal components of TCM and in vitro activity; determining the state of sample cluster by principal component analysis; constructing a logistic regression model of quality grade versus index components and bioactivity and establishing corresponding grade detection formulas of Chinese medicinal materials by fitting a large number of sample data for Chinese medicinal materials from different places of origin and batches. The method of the present invention realizes the mathematical expression of a standard for quality difference of TCM, and provides a feasible solution for the industrialized evaluation of quality grades of Chinese medicinal materials or herbal slices finally.

Abstract: Pharmaceutical micronutrient composition including mixture D in this study helps to mitigate, inhibit, prevent and stop diseases caused by viral infections. The middle east respiratory syndrome-related coronavirus and severe acute respiratory syndrome-related coronavirus as well as their variants and mutants affecting mammals and causing infection are successfully treated using mixture D. Mixture D contains key micronutrients such as an ascorbate, N-acetylcysteine, theaflavins, resveratrol, cruciferous plant extracts, curcumin, quercetin, naringenin, and baicalin and a combination thereof. Additional micronutrients were tested with Mixture D and seemed to have beneficial effects.

Abstract: The present invention discloses a method for protecting mammalian skin against the harmful effects of UV radiation and environmental pollutants, using one or plant actives selected from group comprising a composition comprising not less than 10% w/w oroxylin A, not less than 10% w/w baicalein and not less than 2% w/w chrysin; 95% w/w oxyresveratrol; 95% w/w tetrahydrocurcumin; 90% w/w pterostilbene and a composition comprising at least 10% w/w ?-glucogallin and at least 10% w/w total mucic acid gallates. The invention also discloses a method for cleansing and rejuvenating mammalian skin, exposed to environmental pollutants and UV radiation using the aforesaid plant actives.

Abstract: Provided are a medical ointment of a novel combination containing paeonol and a pharmaceutical use thereof. The medical ointment of a novel combination includes paeonol and panthenol, and further includes at least one selected from Centella asiatica, coenzyme Q10, neomycin sulfate, and pharmaceutically acceptable salts of these. In the medical ointment of a novel combination, specific ingredients that are effective for local pain relief are mixed with ingredients having other effects in a certain ratio to address the problems of the cut treatment ointment of the related art, so that excellent effects may be obtained in relieving itching and reducing pain while inflammation is effectively treated.

Abstract: The present disclosure is directed to a method for producing an olive branch extract having a high oleuropein content. The method includes crushing at least a portion of dried olive branch and extracting olive branch extract from the crushed olive branch with an extraction solvent. The olive variety is at least one selected from Lucca, Mission, and Nevadillo Blanco. The added branch amount of olive branch to the extraction solvent is 10% by weight or more, the extraction solvent is 30% to 50% 1,3-butylene glycol, and the extraction is performed at a temperature in a range of 70° C. to 80° C.

Abstract: Described herein is an invention that includes a spreadable conditioning composition comprising a blend of: a branched hydrocarbon and an ester having a kinematic viscosity of less than or equal to about 100 centistokes. The composition may be natural, for example, if each of the branched hydrocarbon and the ester are independently vegetable-derived. In addition, the composition may lack ingredients that are derived from a palm oil. In an embodiment, the composition is a blend of hydrogenated farnesene and an esters selected from glyceryl triheptanoate, dicapryl succinate, heptyl undecylenate, and mixtures thereof. The composition exhibits an average spreading velocity of about 4 to about 8. Also disclosed are formulations for use in products of personal care, home/institutional care, industry, pharmaceutical and medical and veterinary care and related methods.

Abstract: The invention relates to an active pharmaceutical ingredient consisting exclusively of the combination of (1S,3R,4R,5R)-3-{[(2E)-3-(3,4-)dihydroxyphenyl)-2-propenoyl]oxy}-1,4,5-trihydroxycyclohexanecarboxylic acid and of methyl (2S,3E,4S)-4-{2-[2-(3,4-dihydroxyphenyl)ethoxy]-2-oxoethyl}-3-ethylidene-2-(?-D-glucopyranosyloxy)-3,4-dihydro-2H-pyran-5-carboxylate for use as a drug or veterinary product, particularly in the prevention and/or treatment of pathological disorders of carbohydrate and/or lipid metabolism.

Abstract: The present invention relates to use of a composition for maintenance of bone and/or cartilage health or prevention, alleviation and/or treatment of bone and/or cartilage disorders.

Abstract: The present invention is directed to a new kind of medicinal value or health care function of Eurycoma longifolia extracts, particularly in the treatment or alleviation symptoms and/or conditions associated to hormonal imbalance in females, including menopause and its related symptoms. In one aspect, the present invention discloses the use of a composition comprising a therapeutically effective amount of Eurycoma longifolia extract in the manufacture of a medicament for the alleviation of symptoms and/or conditions associated to hormonal imbalance in females, including menopause and its related symptoms. The alleviation of the symptoms and/or conditions according to the present invention is characterised by inducing a change in the hormonal contents of estrogen, progesterone, follicle stimulating hormone (FSH) and luteinizing hormone (LH). Also disclosed is the use of a pharmaceutical composition comprising the therapeutically effective amount of Eurycoma longifolia extract.

Abstract: A use of an emblica extract in preparing a pharmaceutical composition for protecting mitochondria in retina is provided. When the pharmaceutical composition, which comprises the emblica extract, is provided to retinal cells, a use of the pharmaceutical composition comprises improvement of the ability of performing the oxidative phosphorylation for the synthesis of the adenosine triphosphate (ATP) by the mitochondria in the retinal cells under or exposed to ultraviolet light, and improvement of the coupling efficiency of the synthesis of the adenosine triphosphate by the mitochondria.

Abstract: Pro-toothpaste compositions formulated to receive a volume of allergen solution to provide toothpastes that exhibit efficacy for oral mucosal immunotherapy (OMIT) and acceptable consumer and product stability properties, along with kits of pro-toothpaste, allergen/extracts of allergens, and optionally compounding means and/or specialized toothbrushes are provided. Toothpastes suitable and effective for OMIT and methods for managing allergic symptoms and for reducing risk of allergy in people without symptoms employing the pro-toothpastes, toothpastes and kits of the invention are also disclosed.

Abstract: The present application relates to novel substituted piperidinyltetrahydroquinolines, to processes for their preparation, to their use for the treatment and/or prevention of diseases and to their use for preparing medicaments for the treatment and/or prevention of diseases, in particular for the treatment and/or prevention of diabetic microangiopathies, diabetic ulcers on the extremities, in particular for promoting wound healing of diabetic foot ulcers, diabetic heart failure, diabetic coronary microvascular heart disorders, peripheral and cardial vascular disorders, thromboembolic disorders and ischaemias, peripheral circulatory disturbances, Raynaud's phenomenon, CREST syndrome, microcirculatory disturbances, intermittent claudication, and peripheral and autonomous neuropathies.

Abstract: The present invention provides an egg-laying rate-improving agent for egg-laying hens, quails, or broiler breeders, the egg-laying rate-improving agent being characterized by comprising unheated cashew nut shell liquid, heated cashew nut shell liquid, anacardic acid, cardanol, and/or cardol.

Abstract: An extract of seeds of Emblica officinalis which has triterpenoids and hydroxycinnamic acids is provided. A blend of extracts of seeds of Emblica officinalis which includes an extract of seeds of Emblica officinalis having triterpenoids and hydroxycinnamic acids and an extract of seeds of Emblica officinalis having fatty acids, such as, alpha linolenic acid, linoleic acid and oleic acid is provided. Methods of preparing the extracts of seeds of Emblica officinalis and methods of preparing the blend of extracts of seeds of Emblica officinalis are provided. Methods of treatment administering the extracts of seeds of Emblica officinalis and methods of preparing the blend of extracts of seeds of Emblica officinalis are provided.

Abstract: The present invention relates to a phytocomplex or natural concentrate rich in polyphenolic compounds, such as hydroxytyrosol and 3,4-DHPA-EDA, derived from the vegetation waters of oil-bearing olives or from olive pomace resulting from the olive milling process for use in the treatment and prevention of angiogenesis and inflammation. In particular, the angiogenesis and inflammation to which reference is made is pathologic angiogenesis and inflammation, for example that which sustains the development and spread of a tumor or angiogenesis and inflammation tied to non-tumor pathologies. The present invention further relates to a beverage comprising the polyphenol concentrate and the use thereof in the treatment and prevention of angiogenesis and inflammation.

Abstract: The present disclosure provides a mixture of sugar apple and rosemary extracts, optionally in combination with prickly ash extract, for use as skin care compositions.

Abstract: A nasal spray or therapy solution is provided having organic glycerin; an organic preservative system containing glycerin, citrus reticulata fruit extract, citrus aurantium amara fruit extract, citrus aurantium sinensis peel extract, ascorbic acid, citric acid, lactic acid, water; sodium chloride; water; whereby said nasal spray exhibits inhibited bacteriological growth in vitro for up to 36 months.

Abstract: Provided herein are quinolinone derivatives and their uses as antiviral drugs, for example, for treatment of HSV-1 infection. Also provided herein are pharmaceutically acceptable compositions comprising the quinolinone derivatives and the uses of the composition in the treatment of diseases caused by HSV-1 virus.

Abstract: An oral care composition comprising zinc phosphate, stannous fluoride, arginine or lysine and an organic acid buffer system, as well as methods of using the same.

Abstract: The present invention relates to processes for producing treated olive mill process water (OMPW). In some exemplary embodiments, the treated OMPW is used in the preparation/production of body care products.

Abstract: An oral care composition comprising zinc phosphate, sodium fluoride, stannous pyrophosphate, and an organic acid buffer system, as well as methods of using the same.

Abstract: An oral care composition comprising zinc phosphate, stannous fluoride, arginine or lysine and an organic acid buffer system, as well as methods of using the same.

Abstract: The invention provides methods for classifying a cancer as susceptible to transmembrane prostate androgen induced (TMEPAI)-directed therapies, and methods for treating such cancers. The field of the invention pertains generally to medicine, pathology and oncology. More particularly, it addresses the treatment of breast cancer, such as triple-negative breast cancer, using a transmembrane prostate androgen induced (TMEPAI)-directed therapy.

Abstract: A method of treating an amyloid disease by administration of cactus mucilage extract from Opuntia ficus-indicia is presented. Both gelling and non-gelling cactus mucilage extracts were found to induce changes in the secondary structures of the amyloid beta peptides thus interfering with formation of A? fibrils and aggregation of A? fibrils into plaques.

Abstract: A method for treating skin diseases, wherein a composition having an effective amount of mangosteen rind extract is administered.

Abstract: The present disclosure is related to a method for improving mitochondria in a cell, comprising step of treating the cell with an extraction of Emblica officinalis, for improving ability of mitochondria to perform oxidative phosphorylation and synthesize adenosine triphosphate. The present disclosure is also related to a method for promoting proliferation of a stem cell, comprising step of treating the stem cell with an extraction of Emblica officinalis, for improving division rate of the stem cell.

Abstract: The present invention provides a pharmaceutical composition or a food composition containing combined extracts comprising Schisandrae fructus, Eucommiae cortex and Lycii fructus as active ingredients for preventing or treating metabolic bone diseases. The composition of the present invention does not have side effects as it is a substance derived from natural sources; is effective on osteogenesis in ovariectomized mice; increases the bone content and the bone formation index of serum in real animal model; and reduces the bone resorption index so as to be useful for preventing or treating metabolic bone diseases.

Abstract: The present invention provides a method of producing an olive leaf extract that contains a high concentration of oleuropein. A method of producing an olive leaf extract comprises a first step of grinding dried olive leaves and a second step of mixing grapes with the ground olive leaves and then extracting an olive leaf extract using an extraction solvent. In the second step, the extraction solvent is water, alcohol, or a combination thereof, and extraction is performed at 70° C. or higher.

Abstract: Provided herein are compositions for the administration of chromium that include at least two components: a hydrophilic chromium complex and a lipophilic chromium complex, and methods of using the same. Also provided are compositions for the administration of chromium that include a first “fast-acting” chromium complex and a second “slow-acting” chromium complex, wherein the first chromium complex is absorbed more quickly than the slow-acting chromium complex, and methods of using the same. Also provided herein are methods for treating, preventing, and improving conditions associated with cardiometabolic syndrome, by identifying a subject in need of treatment, prevention, or improvement of a condition associated with cardiometabolic syndrome, and providing a therapeutically effective amount of a composition comprising a fast-acting chromium complex and a slow-acting chromium complex, to the individual.

Abstract: Provided herein are compositions and methods for the treatment of diseases, such as hyperproliferative diseases, employing compounds formulated for pharmaceutical and research use via nanoparticles.

Abstract: The present disclosure is related to a method for improving mitochondria in a cell, comprising step of treating the cell with an extraction of Emblica officinalis, for improving ability of mitochondria to perform oxidative phosphorylation and synthesize adenosine triphosphate. The present disclosure is also related to a method for promoting proliferation of a stem cell, comprising step of treating the stem cell with an extraction of Emblica officinalis, for improving division rate of the stem cell.

Abstract: An oral care composition comprising zinc phosphate, stannous fluoride, arginine or lysine and an organic acid buffer system, as well as methods of using the same.

Abstract: This disclosure relates to extracts from chestnut plants and compositions comprising compounds contained therein. In certain embodiments, the extracts are derived from the leaves of a Castanea plant. In certain embodiments, the disclosure relates to methods of treating or preventing bacterial infections, acne, and other related uses.

Abstract: An oral care composition comprising zinc phosphate, stannous fluoride, arginine or lysine and an organic acid buffer system, as well as methods of using the same.

Abstract: An oral care composition comprising zinc phosphate, sodium fluoride, stannous pyrophosphate, and an organic acid buffer system, as well as methods of using the same.

Abstract: The present invention relates to the technical field of health-care food, especially relates to a traditional Chinese medicine composition for relieving chronic pain and preparation method and use thereof. The traditional Chinese medicine composition includes cinnamon bark oil and nutmeg oil. The traditional Chinese medicine composition of the present invention can effectively relieve chronic pain, and the effect of the composition is superior to single agent, and cinnamon bark oil and nutmeg oil can be used pharmaceutically and bromatologically and do not have side effects.

Abstract: An insect attractant including a blend of volatile organic compounds. The blend of volatile organic compounds may include alpha-phellandrene, beta-caryophyllene, and at least one additional volatile organic compound. In one embodiment, the ratio of alpha-phellandrene to beta-caryophyllene in the blend may be 1:0.5 to 1:2. In one embodiment, the blend of volatile organic compounds may comprise 15 to 60 wt. 0% alpha-phellandrene and 10 to 50 wt. % beta-caryophyllene. In one embodiment, the at least one additional volatile organic compound may be selected from the group consisting of: beta-phellandrene, gamma-terpinene, ocimene, and terpineol.

Abstract: A glucose production method is characterized in that a cellulose raw material is decomposed using a mixture of a cellulolytic enzyme, and saliva or an activating auxiliary agent derived from biological saliva. The method achieves excellent glucose yield.

Abstract: A method for preparing a concentrated extract of Harpagophytum procumbens, in liquid or dry form, having a harpagoside titer greater than or equal to 5%, comprises a step of purifying a crude extract of Harpagophytum procumbens in liquid form in aqueous phase by a technique of liquid-liquid extraction with an organic solvent selected from the esters.

Abstract: A method of increasing the lengths of telomeres in animal cells is practiced by administering an aqueous extract of an Uncaria species to an animal. The animal may be a human and the Uncaria species may be Uncaria tomentosa. Human subjects receiving a daily dose of an aqueous extract of Uncaria tomentosa for a sufficient period of time exhibited an increase in telomere length relative to a baseline measurement taken prior to treatment. The extract may be administered topically or systemically.

Abstract: The present technology provides methods for improving joint function in a subject in need thereof. The methods include administering to the subject an effective amount of a composition comprising one or more of C16:1n7-palmitoleate, derivatives thereof, or pharmaceutically acceptable salts thereof.

Abstract: The use of Kukoamine A and Kukoamine B in the preparation of drugs for the prevention and treatment of sepsis and autoimmune disease is disclosed. Bacterial endotoxin/lipopolysaccaride (LPS) and unmethylated DNA (CpG DNA) of bacteria, the major pathogen-associated molecular patterns in sepsis and autoimmune disease, are specifically targeted, while the disclosed use directionally isolates lead compounds from traditional Chinese medicine. These measures can overcome the major defects of uncertainty of pharmacological material basis and drug targets of extracts and constituents of traditional Chinese medicine. The disclosed use can help in developing a safe, effective and quality controllable drug for prevention and treatment of sepsis and autoimmune disease so as to help solve the present lack of effective drugs in clinical treatment.

Abstract: The disclosure provides compositions containing preparations from plants of the family Marcgraviaceae and from plants of the family Platanaceae. The disclosure also provides methods and uses of plant preparations for treating anxiety, stress and glucocorticoid related disorders.

Abstract: An anti-bacterial mouthwash includes aqueous extracts of Salvia libanotica and Malva sylvestris plants, at least one essential oil, and an emulsifier. The essential oil can include at least one of eucalyptus oil and peppermint oil. The emulsifier can include polyoxyethylene sorbitan. The anti-bacterial mouthwash can be free from alcohol.

Abstract: Compositions obtained from vegetation water from olives and methods for treating patients suffering from an inflammatory skin disease with the compositions are described. Included are hydroxytyrosol rich compounds obtained from olive vegetation water.

Abstract: Compositions and methods for preventing and/or reducing hangover, when consumed before, after or during drinking alcohol. Compositions of the inventions include fructose powder, prickly pear extract, N-acetyl cysteine; kudzu; lemon balm; Vitamin C; nopal; white willow bark extract; milk thistle; Vitamin B1; Vitamin B6; lemon juice; acacia fiber; and other ingredients.

Abstract: The present invention relates to methods and kits for the treatment of breast cancer based on hormone receptor status of progesterone receptor and estrogen receptor comprising the administration of a taxane alone, in combination with at least one other and other therapeutic agents, as well as other treatment modalities useful in the treatment of breast cancer. In particular, the invention relates to the use of nanoparticles comprising paclitaxel and albumin (such as Abraxane®) either alone or in combination with other chemotherapeutic agents or radiation, which may be used for the treatment of breast cancer which does not express estrogen receptor and/or progesterone receptor.

Abstract: Biologically active extracts of one or more Vigna marina (Burm.) Merr., Cocos nucifera L., or Terminalia catappa L. and compositions one or more of the extracts are described. The invention also provides therapeutic and cosmetic uses of the extracts and compositions, in particular for promoting wound healing and for the treatment of skin disorders.

Abstract: The present invention discloses a method of treating cancer comprising administering an effective amount of an alkaloid, in which the alkaloid is liensinine, isoliensinine, dauricine, cepharanthine, hernandezine or thalidezine and isolated from the traditional Chinese medicinal herbs. The use of the alkaloid in treating neurodegenerative disorder is also disclosed.