Abstract: The present invention provides a topical composition having a fermented product of lactic acid bacteria synbiotics as an active ingredient. The fermented product of lactic acid bacteria synbiotics is obtained by performing a fermenting step with lactic acid bacteria and a deactivating step on a fermenting substrate. The lactic acid bacteria are consisting of Lactobacillus salivarius subsp. salicinius AP-32, Bifidobacterium animalis subsp. lactis CP-9 and Lactobacillus acidophilus TYCA06. The fermenting substrate includes animal protein, plant protein and/or plant extracts. The aforementioned fermented product of lactic acid bacteria synbiotics can effectively inhibit the growth of Staphylococcus aureus and/or Propionibacterium acnes, and can be used in the topical composition.

Abstract: The present invention relates to a method for treating or preventing benign prostatic hyperplasia comprising administering an effective amount of a composition consisting essentially of an Aucklandiae Radix extract as an active ingredient to a subject in need of treating or preventing benign prostatic hyperplasia.

Abstract: A cleaning composition including a preservative formulation having a glycine, a diol and a phospholipid complex is disclosed. The cleaning composition can be loaded on a cleaning wipe and used for personal care. The glycine and diol provide a preservative booster to the preservative system for the cleaning composition containing a phospholipid complex, such as cocamidopropyl PG-dimonium chloride phosphate, which has some limited independent preservation activity, depending on the level in the final formulation.

Abstract: Disclosed is a formulation comprising at least two of Rheum palmatum, Chrysanthemum indicum and Sanguisorba officinalis extracts or prevalent molecules therefrom and a pharmaceutically acceptable carrier. Further disclosed is a formulation comprising one or more of Rheum palmatum, Chrysanthemum indicum and Sanguisorba officinalis extracts, or prevalent molecules therefrom in combination with acyclovir and a pharmaceutically acceptable carrier. Disclosed also is a method for treating herpesvirus infections by administering a formulation comprising extracts of Rheum palmatum, Chrysanthemum indicum or Sanguisorba officinalis extracts or prevalent molecules therefrom with or without an antiviral agent, such as acyclovir and a pharmaceutically acceptable carrier.

Abstract: The extract of Agathis robusta as an antifungal agent is prepared by hydrodistillation of the powdered bark of A. robusta in a Clevenger-type apparatus at 100° C. for 6 hours to obtain the essential oils of A. robusta. The essential oil is mixed with an ointment base of cholesterol, liquid paraffin, lanolin, and vaseline album, the powdered essential oil of A. robusta being added to the ointment base at 1 or 2% w/w and homogenized to a smooth ointment. When tested in vivo on Wistar rats topically infected with Candida albicans, both the 1% and 2% ointment formulations demonstrated substantial antifungal activity.

Abstract: In one embodiment, the present invention is directed to a composition comprising an aqueous or ethanolic extract of at least one herb selected from the group consisting of Aloe barbadensis (:F3), Rheum palmatum L. (:B6), Stephania tetrandra (:C4), Phellodendron chinense Schneid. (:D8), Euphorbia humifusa (:S6), Eclipta prostrata (:I2), A. venetum L. (:F1), Portulaca oleracea L. (:F5), and Sanguisorba officinalis L. (:E5), Camellia sinensis var. assamica (Mast.) Kitamura (:PE) and Punica granatum. (:PG), and mixtures thereof. The composition is administered to a patient, in an effective amount, in a method of treating, inhibiting, preventing, reducing the incidence of, ameliorating or resolving a disease state or condition caused in part or exacerbated by hyperactivity of the androgen receptor (AR), by inhibiting the androgen receptor protein. These compositions may also be used inhibit or stabilize hair loss or grow hair in a subject in need.

Abstract: A hair care cream composition including Eclipta alba and arrowroot powder. The compositions are useful for treating hair, such as wavy, curly, or coily/kinky hair.

Abstract: This invention provides novel oral dosage forms comprising a hops extract. The oral dosage forms are capable of activating bitter taste receptors expressed in the gastrointestinal tract. The applications include but are not limited to the use of the oral dosage forms for reducing energy intake and/or appetite in a subject.

Abstract: The copper oxide nanoparticles synthesized using Rhatany root extract involves preparing the Rhatany root extract by adding powdered Rhatany roots to boiling water, allowing the mixture to soak overnight, and removing any solid residue by filtering to obtain the aqueous extract. The copper oxide nanoparticles are prepared by mixing equal volumes of the aqueous Rhatany root extract and 0.1 M aqueous copper sulfate, heating the mixture at 80° C. for 40 minutes, and adding 1 M sodium hydroxide dropwise to the mixture to precipitate CuO. The precipitate is removed by centrifuge, washed with ethanol, dried, and calcined at 400° C. for 4 hours to obtain the copper oxide nanoparticles. The resulting nanoparticles proved effective in degrading wastewater dyes, showed anticancer activity against human cervical cancer by cell viability assay, and showed antibacterial activity against various strains of bacteria by agar diffusion.

Abstract: A composition includes a cannabinoid agent in a range of 0.005% to 1%, a terpene agent in a range of 0.005% to 1%, and a co-fermented herbal complex in a range of 5% to 40%. The cannabinoid agent can include CBD, CBN, CBG, or a combination thereof. The composition can further include ashwagandha.

Abstract: The present invention relates to a method of treating meningioma including administering a Chinese medicine composition to a subject in need thereof; wherein the Chinese medicine composition is an extract of a first mixture comprising Coptis chinensis, Phellodendron amurense, Glycyrrhiza uralensis, Atractylodes lancea, Artemisia carvifolia, Anemarrhena asphodeloides, and Cortex Lycii.

Abstract: An environmentally-friendly preparation method of a composition containing anti-inflammatory ingredients and use of the composition are provided. The method includes: S1. weighing a specified volume of water and adjusting the pH, adding Sophora flavescens roots, and subjecting a resulting mixture to extraction at a high temperature; S2. adjusting pH of an obtained solution in step S1, adding Glycyrrhiza inflata roots, and heating a resulting mixture to boiling for extraction; S3. adding Scutellaria baicalensis roots to an obtained boiling solution from the extraction in step S2, and subjecting a resulting mixture to extraction, filtration, and pH adjustment; S4. adding activated carbon to an obtained filtrate in step S3, and subjecting a resulting mixture to incubation and filtration; S5. adding a clarifying agent to an obtained filtrate in step S4, and subjecting a resulting mixture to standing and filtration; and S6. subjecting an obtained filtrate in step S5 to membrane separation.

Abstract: A composition including a plant medium and a poly-oxygenated metal hydroxide that comprises a clathrate containing oxygen gas molecules. The poly-oxygenated metal hydroxide may comprise of a poly-oxygenated aluminum hydroxide. The composition may include one or more nutrients. The composition may be in a solid form, a fluid form, or a combination thereof. The poly-oxygenated aluminum hydroxide is soluble in a fluid. In one embodiment, the poly-oxygenated metal hydroxide composition may have particles having a diameter of 212 ?m or less, and which may be homogeneous.

Abstract: A method of preparing a Pueraria flower extract rich in isoflavones includes: grinding dry Pueraria flowers to obtain a Pueraria flower powder; adding a first 20-50% ethanol solution to form a mixture, stirring and heating the mixture at 20-80° C. for 1-4 hours, removing the first solution, adding a second 20-50% ethanol solution, stirring and heating the mixture, removing the second solution, and combining the first solution and the second solution to obtain an extract solution; filtering the extract solution to remove solids; concentrating the extract solution under vacuum to obtain a crude extract containing 10-40% solid components; adding anhydrous ethanol solution to reach an ethanol concentration of the crude extract of 75-95%, storing the crude extract at 20-30° C. for 1-4 hours; centrifuging the crude extract at a speed of 2,000-5,000 r/min to obtain a supernatant; and concentrating and spray drying to obtain the Pueraria flower extract without any purification steps.

Abstract: N-Acyl sarcosines of Formula I, wherein, R?C7 alkyl and C10 alkenyl group with terminal double bond, are described as new antimicrobial preservatives for home and personal care products. Lipidated sarcosines of this patent application preserve creams, lotions, emulsions, solutions or suspensions types of formulations of personal care industry. These are used in: leave-on?? (cold cream, sunscreen) as well as: rinse-off?? (facewash, body wash, shampoo) formulations either alone or in combination with other antimicrobials.

Abstract: A composition for improving sleep. In one embodiment, the composition comprises L-Tryptophan, L-Theanine, Reishi mushroom extract, Uridine, a polyphenol, and paeoniflorin. In certain embodiments, the composition further comprises citrus bioflavonoid extract, ?-Oryzanol, holy basil extract, saffron extract, Schisandra chinensis extract, sesamin extract, blueberry extract, quercetin, Polygala tenuifolia root extract, gotu kola extract, ashwagandha extract, betaine, magnesium, or combinations thereof. In other embodiments, the composition further comprises astaxanthin, lycopene, hawthorne extract, or combinations thereof. In certain embodiments, the composition is incorporated into pills. A method for promoting the brain pathways involved in sleep, relaxation, and calmness comprising: ingesting a composition comprising L-Tryptophan, L-Theanine, Reishi mushroom extract, Uridine, a polyphenol, and paeoniflorin. In one method, the composition is ingested at least one and a half hours before bedtime.

Abstract: Provided herein are methods of treatment of psychiatric disorders requiring treatment with an antipsychotic drug, such as schizophrenia or schizoaffective disorder, comprising administration of both the antipsychotic drug and a W. somnifera plant part, extract, chemical constituent(s) thereof, or a derivative thereof to treat symptoms of the psychiatric disorder. Treatment is typically continued for at least four weeks. A combination dosage form comprising both the antipsychotic drug and the W. somnifera plant part, extract, chemical constituent(s) thereof, or a derivative thereof in amounts effective to treat the psychiatric disorder.

Abstract: Methods for, among other things, improving sleep, energy and social interaction and reducing concern or worry in mammals are provided. In one embodiment, the method includes administering a tablet, capsule or caplet of 190 mg to 3200 mg of compositions that include extracts of Crateva nurvala, Equisetum arvense, Lindera aggregata, and Zea mays daily.

Abstract: A method for stimulating or enhancing the immune system with a composition that includes a Eurycoma longifolia aqueous extract. Also provided is a method for reducing the risk of infectious disease by administering the composition. Further disclosed is a method for treating an individual with a Eurycoma longifolia aqueous extract to increase the number of T-cells, improve Scoring of Immunological Vigor, lower immunological age, reduce fatigue, or alleviate or reduce stress.

Abstract: A shrimp-like food has mannan-containing fibrous portions and a mannan-containing binding portion binding between the fibrous portions. The fibrous portions are preferably arranged in a random orientation in the food. The fibrous portions preferably have a thickness of 0.8 to 3.0 mm. The mannan contents in the fibrous and binding portions are both preferably 1 to 7 mass %.

Abstract: The present disclosure relates to pharmaceutical compositions including an active substance with antimicrobial, antiviral, and immunoistimulatory activities. The disclosure further provides methods of treating bacterial or viral infections and methods of enhancing immune function using the active substance.

Abstract: A composition including a plant medium and a poly-oxygenated metal hydroxide that comprises a clathrate containing oxygen gas molecules. The poly-oxygenated metal hydroxide may comprise of a poly-oxygenated aluminum hydroxide. The composition may include one or more nutrients. The composition may be in a solid form, a fluid form, or a combination thereof. The poly-oxygenated aluminum hydroxide is soluble in a fluid. In one embodiment, the poly-oxygenated metal hydroxide composition may have particles having a diameter of 212 ?m or less, and which may be homogeneous.

Abstract: In various embodiments a cancer treatment method is provided based on inhibition of proline catabolism. When combined with p53 restoration therapy and/or inhibition of glutaminase, the inhibition of proline catabolism results in a “synthetic lethal” and synergistic anticancer response. Novel suicide inhibitors that induce the degradation of proline dehydrogenase (PRODH) are also provided. Also provided is a method of assaying PRODH to identify responders/non-responders to inhibition of proline catabolism and/or glutaminase.

Abstract: There are provided isotope-enriched compounds of Formula (I) and pharmaceutically acceptable salts or esters thereof, as well as pharmaceutical compositions thereof and methods of use thereof for prevention and treatment of amyloid-? related diseases, such as Alzheimer's disease.

Abstract: Disclosed are a pharmaceutical composition and a health functional food for the prevention and treatment of diabetic peripheral neuropathy, comprising an herb extract of a mixture of 3.5:1 Dioscorea Rhizoma:Dioscorea nipponica (w/w). Having the ability to synergistically increase in vivo levels of nerve growth factor, compared to the extracts from the herbs alone or her mixtures of other weight ratios, the mixed herb extract is effective for preventing the apoptosis of nerve cells and promoting nerve regeneration. Thus, it can be applied to pharmaceutical compositions and health function foods preventive and curative of diabetic peripheral neuropathy.

Abstract: Method for treating melanoma is provided.

Abstract: The invention relates to an extract of Ashwagandha that exhibit enhanced bioactivity and bioavailability comprising of enriched withanolide glycosides and saponins; with negligible amount of alkaloids, withanolide aglycones and oligosaccharides. The extract as disclosed prepared from root, stems, leaves and whole plant of Ashwagandha further shows improved immunomodulatory activity, anti-inflammatory activity, anti stress activity, antidiabetic activity and sleep quality. The disclosure also provides a method of improving bioactivity of withanolide glycosides even at lower doses, by the administration of an enteric coated formulation of extract of Ashwagandha to humans. The enteric coating protects the composition from hydrolysis in the acidic environment of the stomach to release the withanolide glycoside in neutral/alkaline pH in gastrointestinal tract (GIT) thus enhancing the absorption.

Abstract: The present invention relates to a wet tissue containing a hot water extract of Coptidis Rhizoma extracted under high temperature and high pressure conditions, or a distillate thereof, and more specifically, to a wet tissue containing a hot water extract of Coptidis Rhizoma obtained by mixing 2,000-8,000 parts by weight of water on the basis of 100 parts by weight of Coptidis Rhizoma and extracting the same under high temperature and high pressure conditions of 120-131° C. and 1.2-2.8 atm, respectively, or a distillate thereof. The wet tissue containing a hot water extract of Coptidis Rhizoma or a distillate thereof shows remarkable antibacterial and fungicidal activities against pathogenic microorganisms existing in the skin and has an excellent inflammation inhibitory effect, and thus can be readily used for cleaning the skin and alleviating various inflammatory diseases.

Abstract: The present invention relates to the use of garcinol as a nephroprotective agent. The present invention also relates to the use of garcinol as a therapeutic agent in renal disorders, in particular diabetic nephropathy, and to medicinal preparations containing garcinol. Further disclosed herein are method of treatment of renal disorders, in particular diabetic nephropathy by administration of garcinol.

Abstract: In some embodiments, a composition for the treatment and inhibition or prevention of arthritic diseases includes an extract of mixed herbs, the mixed herbs including an active ingredient with Lonicera japonica THUNB and Anemarrhena asphodeloides BUNGE.

Abstract: The present invention relates to a novel use of sesquiterpenoid compounds, the pharmaceutically acceptable salts thereof, or the extracts of Cyperus rotundus comprising same or the fractions thereof in the prevention or treatment of menopausal diseases. The sesquiterpenoid compound according to the present invention, the extracts of Cyperus rotundus comprising the same or fractions thereof exhibit excellent estrogenic activity or anti-allergic activity, and therefore they can be used for the prevention or treatment of menopausal diseases caused by a decline in estrogen level or by allergic diseases.

Abstract: A method for stimulating collagen synthesis in aging skin cells in need of treatment by stimulating SIRT1, SIRT3, and SIRT6 and a method for preparing a topical composition for stimulating SIRT1, SIRT3, and SIRT6 in skin cells.

Abstract: The present invention relates to a composition for use in the treatment of an intestinal tract disorder caused by a gluten-associated protein, said composition comprising at least one agent which binds to the gluten-associated protein, characterized in that the composition is administered at the same time as or at most within 60 minutes after administration of at least one tannin to a patient.

Abstract: The invention relates to methods useful in studying or modulating skin or hair pigmentation and to the use of plant extracts in compositions as well as to methods comprising the topical use of such compositions to reduce or to enhance skin or hair pigmentation.

Abstract: A method for treating, preventing or ameliorating breast cancer is provided by administering a synergistic amount of digitoxin and either actein or an extract of black cohosh comprising triterpene glycosides, and optionally another chemopreventive agent which may be paclitaxel. Methods for treating or preventing a neoplasia using a synergistic combination, and compositions of a synergistic combination of a cardiac glycoside and either actein or an extract of black cohosh comprising triterpene glycosides, and optionally another chemopreventive agent which may be a taxane are also provided. The compositions may also be used in a method for modulating Na+K+ATPase activity. In addition, a method for inhibiting the progression or development of breast cancer in vivo by administering either actein or an extract of black cohosh comprising triterpene glycosides and optionally at least one other chemoprotective agent is provided.

Abstract: A method of modifying the content of certain chemical compounds in tobacco materials is provided, the method including treatment of a tobacco plant or portion thereof with at least one enzyme. For example, the method may modify the content of tobacco smoke toxicant precursors in tobacco materials, which can result in a modification in toxicant production when the tobacco material is exposed to elevated temperatures. The type of tobacco plant or portion thereof treated according to the invention can be, for example, a tobacco seed, a tobacco seedling, an immature live plant, a mature live plant, a harvested plant, or a plant derivative. Smoking articles and other tobacco products including such enzyme-treated tobacco materials are also provided.

Abstract: The present invention provides a composition for use in treating or preventing neoplasia, comprising an effective actein. The present invention also provides a composition for use in treating or preventing neoplasia, comprising an effective anti-neoplastic amount of an ethyl acetate extract of black cohosh. The present invention further provides a combination of anti-neoplastic agents, comprising an effective anti-neoplastic amount of an ethyl acetate extract of black cohosh and an effective anti-neoplastic amount of at least one additional chemopreventive or chemotherapeutic agent. Methods for treating and preventing neoplasia are also provided.

Abstract: The present invention provides inhibitors of I?B kinase of general formula (I). or a stereoisomer or physiologically tolerable salt thereof, for use in the inhibition of the growth of a multiple myeloma cell and for use in the treatment of multiple myeloma, wherein R1-R8 and B6-B9 are described in the specification.

Abstract: The present invention refers to the use of HMP (a secondary metabolite obtained from Aspergillus fungi) as an agent that intensifies the mechanism of macrophage activation, leading to the death of L. (Leishmania) amazonensis, the etiologic agent of cutaneous leishmaniasis. The main mechanism of action of this agent is the activation of the microbicidal activity of host cells, through increased superoxide production, number of lysosomes, actin and microtubule filament polymerization and increased spreading, typical of activated cells. Additionally, HMP represents a molecule of easy acquisition, presents an efficient combat mechanism with no adverse reactions and capacity to inhibit the development of promastigotes and amastigotes forms. Finally, results suggest HMP to be a potential candidate for use against cutaneous leishmaniasis at a minimal concentration of 50 ?g/mL.

Abstract: The present invention relates to a micro-particle for extending satiety and controlling blood glucose and lipid levels, comprising a core having the protein extract from sweet potato, an active ingredient layer coated on the core, and a protection layer coated over the active ingredient layer as an external layer, wherein the protein extract from sweet potato contains trypsin inhibitor and glycoprotein. The micro-particle comprising a protein extract from sweet potato can effectively extend satiety, control blood glucose and lipid levels and increase metabolism effectively.

Abstract: The present invention provides a pharmaceutical composition or a cosmetic product which can accelerate production of ceramide in cells. The ceramide production-accelerating agent contains a plant selected from the group consisting of Radix Heraclei Scabridi, Rhizoma Dioscoreae, Radix Rehmanniae, Rhizoma Atractylodis Macrocephalae, Radix Glycyrrhizae, Radix Et Rhizoma Rhei, Pseudobulbus Bletillae, Radix Polygoni Multiflori, Radix Platycodi, and Herba Leonuli, or an extract thereof as an active ingredient. Further, the present invention provides a moisturizing agent containing a plant selected from the group consisting of Herba Leonuri and Rhizoma Dioscoreae, or an extract thereof as an active ingredient.

Abstract: The present invention describes the obtaining process of the dichloromethane fraction and subfractions from Eleutherine plicata, popularly known as “marupazinho, marupari, palmeirinha, coquinho, marupaí, marupaú, marupá-piranga, and lirio-folha-de-palmeira”. This invention comprises the obtaining process of pharmaceutical compositions that contain the dichloromethane fraction and/or naphthoquinone, as well as its use for malaria treatment. Extract and fractions were assayed and presented antiplasmodial activity, particularly against chloroquine-resistant Plasmodium falciparum (clone W2).

Abstract: A treatment protocol for use in the treatment of neurocutaneous syndrome is described and comprises at least one xanthone component, which may comprise at least one mangosteen component, and at least one detoxification component. Additional embodiments comprise at least one herbal component, at least one vitamin component, or a combination thereof. A method of treating a patient having neurocutaneous syndrome is described herein and comprises: providing at least one xanthone component, which may comprise at least one mangosteen component, providing at least one xanthone component, which may comprise at least one mangosteen component, to the patient, and administering the at least one detoxification component to the patient. Additional methods steps may include providing and administering at least one herbal component, providing and administering at least one vitamin component or a combination thereof.

Abstract: The present invention relates to topical compositions containing fermented extracts of Traditional Chinese Medicinal (TCM) ingredients for improving the appearance and skin condition of the user. The topical compositions of the present invention are tailored for different users of different skin compositions according to TCM principles. The fermented TCM extracts are characterized by reduced odor and/or color in comparison with unfermented TCM extracts and are therefore more suitable for use in cosmetic products.

Abstract: A composition for enhanced bioavailability of curcumin including purified curcuminoid and purified essential oil of turmeric. A method to prepare a composition for enhanced bioavailability of curcumin having purified curcuminoid and purified essential oil of turmeric.

Abstract: A cosmetic active ingredient obtained from roots of Paeonia albiflora, which is a hydrolyzate of roots of Paeonia albiflora including at least 30% of carbohydrates by weight relative to the total weight of dry materials. The cosmetic active ingredient can be used in a composition and in a cosmetic care process for care of the human skin.

Abstract: This invention relates to a Chinese medicinal formulation for the treatment of inflammatory bowel diseases, and a method of preparation thereof. The formulation comprises herbal components selected from a group consisting of Radix Codonopsis (Dangshen), Rhizoma Atractylodis Macrocephalae (Bai Zhu), Sclerotium Poriae Cocos (Fu Ling), Rhizoma Zingiberis Officinalis (Gan Jiang), Radix Paeoniae Alba (Bai Shao) and Rhizoma Coptidis (Huanglian).

Abstract: A method for preparing a Smilax china L. root extract having an increased active ingredient content, and a beverage composition for detoxification including the same are provided. The method for preparing a Smilax china L. root extract includes preparing a powder of a Smilax china L. root, obtaining an ethanol extract of Smilax china L. root from the powder of Smilax china L. root using ethanol, and concentrating the ethanol extract of Smilax china L. root under a reduced vacuum to obtain a concentrate having a reduced ethanol content.

Abstract: The present invention provides a skin care product comprising at least two enhancers and at least one skin care ingredient, wherein the at least two enhancers are selected from cyclodextrin, pentasodium pentetate, phytic acid, potassium citrate, sodium citrate, potassium gluconate and sodium gluconate.

Abstract: A composition for suppressing cough, removing sputum, preventing and/or treating a respiratory disease comprising an extract of Coptidis rhizoma or a combined extract of Coptidis rhizoma with ivy leaf as an active ingredient, and a method of suppressing cough, removing sputum, and/or preventing and/or treating respiratory disease using the composition, are provided.