Containing Or Obtained From A Seed Or Nut Patents (Class 424/776)
  • Patent number: 7018663
    Abstract: The invention is directed to a composition and method in which dried stinging nettle is applied to the skin proximate a pain site to alleviate pain associated with various inflammatory conditions. The characteristic sting of the stinging nettle is absent in the dried nettle of the composition and method.
    Type: Grant
    Filed: November 21, 2002
    Date of Patent: March 28, 2006
    Inventor: Donald E. Scott
  • Patent number: 7011856
    Abstract: A composition including an extract of buckwheat seed and a fractionation product of the extract of buckwheat seed useful for the prevention and therapy of aging is disclosed. The composition prevents, treats and improves aging phenomena such as the symptoms of Alzheimer's syndrome and pathological lesions of the brain. Further, the composition activates and improves the function of a brain including the ability to learn, memorize, and think, as well as providing other physiological benefits.
    Type: Grant
    Filed: February 28, 2002
    Date of Patent: March 14, 2006
    Assignee: Amino Up Chemical Co., Ltd.
    Inventor: Ken-ichi Kosuna
  • Patent number: 7001623
    Abstract: A method for the preparation of a handleable, flowable coated cottonseed product is provided which involves coating cottonseed with a composition of (a) water or a liquid feed product, (b) one or more organic acids and (c) a metal compound capable of interacting with the one or more organic acids to form a coating on the cottonseed, and curing the coating formed thereby, and the flowable cottonseed product formed thereby, as well as its use as a feed supplement for ruminants such as cattle, as a plantable source of cottonseed, in a method for treatment and/or prevention of urinary calculi or prevention of milk fever in cattle, or in a method for increasing milk fat in dairy cattle, a method for increasing milk production in dairy cattle, and a method for preventing ketosis in ruminants.
    Type: Grant
    Filed: September 13, 2001
    Date of Patent: February 21, 2006
    Assignee: Ajinomoto U.S.A. Inc.
    Inventors: Paul Summer, Koryu Yamamoto, Ross Dale
  • Patent number: 6991818
    Abstract: The invention relates to a novel compound isosquamocin obtained from the plant Annona squamosa; also provides insecticidal compositions containing isosquamocin, squamocin-B (9), squamocin-C (6), squamocin-G (2), squamocin-H (3), squamocin-J (7), squamocin-K (8), squamocin-L (5), squamocin-M (4), squamostatin-A (10), bullatalicin (11), bullatanocin (12) and three unidentified related compounds with retention times 5.88, 14.18 and 45.25 min. in HPLC obtained from the plant Annona squamosa and a process for the preparation of the novel compound and the insecticidal composition.
    Type: Grant
    Filed: March 28, 2002
    Date of Patent: January 31, 2006
    Assignee: Council of Scientific & Industrial Research
    Inventors: Akella Venkata Bhavani Shankaram, Madugula Marthanda Murthy, Dattatreya Manohar Akkewar, Mukkamala Subramanyam, Attaluri Narasimha Rao
  • Patent number: 6977089
    Abstract: Methods of using pomegranate extracts of the present invention for treating patients with atherosclerosis, or increased intima-media thickness of an artery, are provided. The methods comprise the step of administering to the patient a composition comprising a therapeutically effective amount of an extract from pomegranate. The methods of the present invention may also be used to decrease the incidence of stroke or heart attack in a patient.
    Type: Grant
    Filed: November 4, 2003
    Date of Patent: December 20, 2005
    Assignee: Stewart and Lynda Resnick Revocable Trust
    Inventors: Michael Aviram, Leslie Dornfeld
  • Patent number: 6964786
    Abstract: The present invention relates to a novel oil extracted from the seeds of Momordica charantia L., for topical application to a body of mammal and used as anti-inflammatory, anti-arthritic, vasculodilatory and wound healing agent, said oil essentially comprising capric acid 0.7–1.2% by wt., lauric acid 0.6–1% by wt., palmitic acid 42–5.0% by wt., stearic acid 59–62% by wt., oleic acid 13–15% by wt., archid acid 3–5% by wt., linoleic acid 8–10% by wt., and other undetected minor acids 6–8% by wt.; and a process for producing such oil.
    Type: Grant
    Filed: July 15, 1999
    Date of Patent: November 15, 2005
    Inventor: Pushpa Khanna
  • Patent number: 6946154
    Abstract: The present invention relates to a one step process for the preparation of antibacterial and antioxidant fraction from the unconventional parts of Seabuckthorn (Hippophae rhamnoides L.).
    Type: Grant
    Filed: March 25, 2003
    Date of Patent: September 20, 2005
    Assignee: Council of Scientific and Industrial Research
    Inventors: Attar Singh Chauhan, Pradeep Singh Negi, Ramesh Shyam Ramteke
  • Patent number: 6942882
    Abstract: A hepatic disorder suppressant comprising extracts having hepatic disorder suppressing effect as effective ingredients, wherein the extracts is obtained by extracting an avocado plant and/or a processed product thereof with an organic solvent is disclosed.
    Type: Grant
    Filed: October 11, 2002
    Date of Patent: September 13, 2005
    Assignee: Kagome Co., Ltd.
    Inventors: Yasushi Arimoto, Hiroyuki Suganuma, Takahiro Inakuma, Kimio Sugiyama, He Puming, Hirokazu Kawagishi
  • Patent number: 6936282
    Abstract: The present invention provides a composition including at least six of the following traditional Chinese medicines: Ren Shen, Dang Gui, Huang Qi, Gan Cao, Chai Hu, Huang Lian, Tian Zhu Huang, Huang Qin. The composition possesses pharmaceutical activities of inhibiting platelet aggregation and prolonging bleeding time, and can be used in preventing and treating a cerebrovascular disease.
    Type: Grant
    Filed: March 27, 2003
    Date of Patent: August 30, 2005
    Assignee: BrainGenesis Biotechnology Co., Ltd.
    Inventor: Ken-Shung Huang
  • Patent number: 6932990
    Abstract: This invention provides carbohydrate absorption inhibitor derived from evening primrose seed which is significantly effective to prevent and cure diabetes mellitus and prevent obesity, and the manufacturing method of the same. Carbohydrate absorption inhibitor in this invention is characterized that the effective component is an alcohol extract of evening primrose seed. The aforementioned evening primrose seed is preferably a defatted evening primrose seed. Extracting solvent of the aforementioned evening primrose seed is preferably ethanol, or preferably a 70 to 85% (v/v) aqueous ethanol. Also, this invention is characterized that the carbohydrate absorption inhibitor is an effective component of polyphenol derived from evening primrose seed. The polyphenol is preferably one or more substances selected from among gallic acid, ellagic acid, catechin, pentagalloylglucose, procyanidin, and proantocyanidin.
    Type: Grant
    Filed: July 26, 2001
    Date of Patent: August 23, 2005
    Assignee: Oryza Oil & Fat Chemical Co., Ltd.
    Inventors: Yotaro Konishi, Michio Aitani, Hiroshi Yamaguchi, Tsutomi Arimuba, Tadashi Okada, Hiromichi Murai
  • Patent number: 6921543
    Abstract: A method for modulating the immune response to an immunogen in a human or animal patient comprises administration to the patient of an immunogenically effective amount of the immunogen and an immunomodulatory effective amount of a lipid extract of Perna canaliculus or Mytilus edulis.
    Type: Grant
    Filed: September 21, 2001
    Date of Patent: July 26, 2005
    Assignee: Pharmalink International Limited
    Inventors: Larisa G Rudenko, Robert Borland, Anatoly Naychin
  • Patent number: 6905715
    Abstract: The present invention is directed to a method of processing a fat-containing bean, e.g., cocoa beans, for producing solids comprising active polyphenols and/or fat-containing products, comprising extracting the fat to produce solids and fat-containing products. Additionally, the inventive methods also provides cocoa compositions comprising at least one active polyphenol, wherein the concentration of the polyphenol(s) with respect to the nonfat solids is conserved with respect to the concentration of the active polyphenol(s) in the bean from which the compositions are derived.
    Type: Grant
    Filed: August 26, 2003
    Date of Patent: June 14, 2005
    Assignee: Mars, Incorporated
    Inventors: Kirk S. Kealey, Rodney M. Snyder, Leo J. Romanczyk, Jr., John F. Hammerstone, Jr., Margaret M. Buck, Giovanni G. Cipolla
  • Patent number: 6905713
    Abstract: The present invention provides a method for processing defatted oil seeds, comprising the steps of: (a) solubilizing at least a portion of the protein contained in the oil seeds to produce suspended residual solids and a first solution comprising protein, phenolic-protein complexes, and free phenolic compounds; (b) separating at least a portion of the free phenolic compounds from the first solution and recovering a free phenolic reduced solution; and (c) treating the free phenolic reduced solution to precipitate at least a portion of the protein as a precipitated protein isolate and recovering a treated solution containing a soluble protein isolate. Novel protein products are also disclosed. Food and drink products containing the novel protein products are also disclosed.
    Type: Grant
    Filed: May 28, 2002
    Date of Patent: June 14, 2005
    Inventors: Levente Laszlo Diosady, Lei Xu, Bih-King Chen
  • Patent number: 6890565
    Abstract: The invention relates to a process for preparing proteins that can act as effective coagulants in the treatment and purification of contaminated water. In particular, the invention relates to a process for extracting coagulant protein derivatives from the seeds of trees from the family Moringaceae. The invention also relates to coagulation protein preparations prepared by the process, and the use of such preparations for the treatment and purification of contaminated water.
    Type: Grant
    Filed: April 2, 2001
    Date of Patent: May 10, 2005
    Assignee: Optima Environnment S.A.
    Inventor: John Paul Sutherland
  • Patent number: 6887501
    Abstract: The present invention is directed to a method of processing a fat-containing bean, e.g., cocoa beans, for producing solids comprising active polyphenols and/or fat-containing products, comprising extracting the fat to produce solids and fat-containing products. Additionally, the inventive method also provides cocoa compositions comprising at least one active polyphenol, wherein the concentration of the polyphenol(s) with respect to the nonfat solids is conserved with respect to the concentration of the active polyphenol(s) in the bean from which the compositions are derived.
    Type: Grant
    Filed: August 7, 2003
    Date of Patent: May 3, 2005
    Assignee: Mars, Incorporated
    Inventors: Kirk S. Kealey, Rodney M. Snyder, Leo J. Romanczyk, Jr., John F. Hammerstone, Jr., Margaret M. Buck, Giovanni G. Cipolla
  • Patent number: 6887498
    Abstract: A method for preparing a Bowman-Birk inhibitor (BBI) product from soybeans is provided. The product produced in accordance with the method of the invention and compositions including the product are also provided. BBI product produced in accordance with the invention is a significantly improved inhibiter of malignant cell transformation and methods for its administration to prevent or inhibit progression of cancer are provided.
    Type: Grant
    Filed: July 16, 2002
    Date of Patent: May 3, 2005
    Assignee: SOLAE, LLC
    Inventors: Arthur H. Konwinski, Bernard F. Szuhaj
  • Patent number: 6887497
    Abstract: The present invention involves a composition for oral ingestion that contains effective amounts of Glucosamine sulfate, Nettle Leaf, Quercetin, curcumin extract/curcuminoids, Selenium, Zinc, Vitamin C (calcium ascorbate) and Grape Seed Extract, as well as other ingredients and healthy filler ingredients. More specifically, this formulated product is a cartilage and joint maintenance and repair formulation. This formulation allows for enhanced function of joints and cartilage to treat and prevent osteoarthritis, rheumatoid arthritis and other joint ailments/diseases.
    Type: Grant
    Filed: December 19, 2002
    Date of Patent: May 3, 2005
    Assignee: Vitacost.com, Inc.
    Inventor: Wayne F. Gorsek
  • Patent number: 6887500
    Abstract: The present invention relates to natural compositions for lowering blood pressure, and treating various conditions associated with the occurrence of high blood pressure. These compositions can comprise two or more of the following ingredients in amounts which are effective to treat blood pressure conditions, e.g., (a) Hainan Holly leaf (e.g., Ilex hainanensis Merr.), (b) Chinese Hawthorn fruit (e.g., Crataegus pinnatifida Bge. or Crataegus cuneata Sieb. et Zucc.), (c) Garden radish seed (Raphanus sativus L.), and (d) Oriental persimmon leaf (Diospyros kaki L.f).
    Type: Grant
    Filed: May 6, 2003
    Date of Patent: May 3, 2005
    Inventor: Rulin Xiu
  • Patent number: 6884442
    Abstract: An anti-inflammatory agent exhibiting an anti-inflammatory function is provided, which includes either a set of dried substances or an extract of Perilla leaf, Cacao and Fennel, and preferably Perilla leaf, Cacao, Fennel, Fenugreek seed, Rosemary, Juniper berry and Celery seed. This specific set or combination of those natural herbs is effective to relax and suppress symptoms of allergy, particularly holistic symptoms of allergic rhinitis, without causing any substantive adverse effects. Since all of the ingredients included in agent are derived from the natural herbs, a long-term administration of the agent may cause substantively no adverse effects. Also, inclusion of the agent into foods and drinks is also useful.
    Type: Grant
    Filed: October 25, 2002
    Date of Patent: April 26, 2005
    Assignee: Herb Road Company
    Inventor: Michio Tani
  • Patent number: 6881425
    Abstract: The present invention relates to a herbal health protective, promotive neutraceutical formulation for women, human expectant mothers and lactating mothers, and also relates to a process for the preparation of custom made herbal health protective, promotive nutraceutical formulations as food supplements to ameliorate the general health of females with optimum nutrients, said process comprises the base product of microwave oven roasted seed powders mixture from selected genera of Glycine, Phaseolus, Cicer, Psophocarpus, Mucuna, Triticum, Hordeum, Amaranthus, Chenopodium and Fagopyrum, fortified with the natural herbs/medicinal plants extract from the genera Centella, Withania, Pueraria, Asparagus, Chlorophytum, Boerhaavia, Sida, Saraca and also some other ingredients like pale sugar powder, jaggary, milk powder, coca powder, Elettaria cardamomum (Elaichi) powder, Piper longum (Pippali) fruit powder, Myristica fragrans (Jaiphal) fruit powder were also added to get the final nutraceuticals; the nutraceuticals are
    Type: Grant
    Filed: August 31, 2001
    Date of Patent: April 19, 2005
    Assignee: Council of Scientific and Industrial Research
    Inventors: Palpu Pushpangadan, Dhan Prakash
  • Patent number: 6875453
    Abstract: A non-toxic mucosal disinfectant for topical application in the nose, skin, mouth and hard surfaces comprising a composition of 99.0% isopropyl alcohol of at least 24.0% by weight; sesame oil not exceeding 73.0% by weight and lemon oil of less than 3.0% by weight and menthol less than 1.0% by weight. All of the components are mixed homogenously with the sesame oil supplementing and neutralizing the dehydrating effect of the alcohol.
    Type: Grant
    Filed: April 2, 2004
    Date of Patent: April 5, 2005
    Inventor: Manuel Viamonte, Jr.
  • Patent number: 6869623
    Abstract: A non-toxic mucosal disinfectant for topical application in the nose has a composition of 91% isopropyl alcohol of at least 50% by weight; sesame oil not exceeding 45% by weight, lemon oil of about 2% by weight, aloe of about 5-10% by weight, and optional components of chlorhexidine gluconate and grapefruit seed extract. All of the components are mixed homogeneously, with the sesame oil supplementing and neutralizing the dehydrating effect of the alcohol.
    Type: Grant
    Filed: July 21, 2003
    Date of Patent: March 22, 2005
    Inventors: Manuel Viamonte, Jr., Laurence M. Shanley
  • Patent number: 6866874
    Abstract: Compositions are described comprising at least partially defatted meal from a plant source containing protein-bound tryptophan, preferably squash seeds, and, optionally, a carbohydrate source provided in an amount capable of facilitating transport of in vivo generated tryptophan across the blood brain barrier. Also described are dietary supplements, foods and beverages comprising the composition of the invention to reduce anxiety.
    Type: Grant
    Filed: November 8, 2002
    Date of Patent: March 15, 2005
    Inventors: Susan P. Hudson, Craig J. Hudson
  • Patent number: 6866875
    Abstract: A method of producing a pine cone extract and the pine cone extract produced there from, wherein the pine cone extract is useful in increasing the effects of nucleic acid vaccines and medicaments; and useful in the production of phenotypically immature and/or mature dendritic and/or fibrocyte cells.
    Type: Grant
    Filed: September 26, 2001
    Date of Patent: March 15, 2005
    Assignee: Tampa Bay Research Institute
    Inventors: Akiko Tanaka, John Jessip, William Guy Bradley
  • Patent number: 6858233
    Abstract: The invention provides a process for reducing odour, bitterness, astringency and pungency of a Simmondsins extract by dissolving the Simmondsins extract in a solvent if the Simmondsins extract is in a dry form, reacting the liquid Simmondsins extract with a carbonaceous adsorbent, such as activated carbon, to obtain a mixture, separating the adsorbent from the mixture to obtain a purified liquid extract, and drying the purified liquid extract.
    Type: Grant
    Filed: July 3, 2003
    Date of Patent: February 22, 2005
    Assignee: International Flora Technologies, Ltd.
    Inventors: Qingnong Tang, James Howard Brown, Wenhui Fu
  • Patent number: 6855353
    Abstract: A pharmaceutical composition for prevention and treatment of cancer, cardiovascular disease and antioxidation contains resveratol. The new method of process for producing resveratol is extracted resveratol from oil residue and stems of peanuts or stems of other cheap herbs. Derivates of resveratol include procyanidins, polydatin, peceid, anthraglycoside, emodin, chrysophanol and quercetin.
    Type: Grant
    Filed: March 8, 2002
    Date of Patent: February 15, 2005
    Inventor: Yaguang Liu
  • Patent number: 6855347
    Abstract: The present invention relates to a novel synergistic herbal composition for the treatment of gastric ulcer, a method for preparing said synergistic herbal composition and a process for the treatment of gastric ulcer using said composition and more particularly, the present invention relates to a novel synergistic herbal composition which is effective against pyloric ligation induced ulcer model and histamine induced ulcer model.
    Type: Grant
    Filed: March 25, 2002
    Date of Patent: February 15, 2005
    Assignee: Council of Scientific and Industrial Research
    Inventors: Janaswamy Madhusudana Rao, Upparapalli Sampathkumar, Boggavarapu Subrahmanya Sastry, Jhillu Singh Yadav, Kondapuram Vijaya Raghavan, Gautam Palit, Deepak Rai, Panniyampally Madhavankutty Varier, Trikovil Sankaran Muraleedharan, Kollath Muraleedharan
  • Patent number: 6852315
    Abstract: A method has been discovered for the epoxidation of a compound having at least one carbon-carbon double bond, the method involves reacting a compound having at least one carbon-carbon double bond, a solvent, an oxidant, and membrane bound peroxygenase. Also discovered is a method for preparing the membrane bound peroxygenase involving grinding seeds containing peroxygenase to produce ground seeds, homogenizing the ground seeds in a buffer to form a slurry, centrifuging the slurry to produce a first supernatant, centrifuging the first supernatant to produce a second supernatant, and filtering said second supernatant through a protein-binding membrane filter to produce membrane bound peroxygenase; optionally the second supernatant is filtered through a hydrophilic membrane filter prior to filtering the second supernatant through a protein-binding membrane filter.
    Type: Grant
    Filed: October 3, 2002
    Date of Patent: February 8, 2005
    Assignee: The United States of America as represented by the Secretary of Agriculture
    Inventors: George J. Piazza, Thomas A. Foglia, Alberto Nunez
  • Patent number: 6846499
    Abstract: In accordance with the present invention Jojoba Oil may be used in accordance with the treatment of and preventative measures associated with Gynecology of Obstetrics and general surgery, as well as in the treatment of eye diseases, inflammation of the internal, middle or external ear, rheumatic pain and arthritis, gingivostomatitis, toothache and dermal diseases. Jojoba oil is a natural product and is characterized by being non-irritant and non-allergic to skin and mucous membrane. This oil has lubricant, moisturizing and soothing properties, as well as having anti-bacterial, anti-inflammatory and anti-oxidant properties. It has a very high healing power and improves blood circulation, and also has high penetration into stratum corneum.
    Type: Grant
    Filed: July 3, 2002
    Date of Patent: January 25, 2005
    Assignee: Natoil & Sedico
    Inventor: Nabil Sadek El Mogy
  • Patent number: 6841174
    Abstract: The invention provides herbal compositions with antiviral properties comprising extracts of Foeniculum vulgare, Nigella sativa, Centaurium erythrae (spicatum or pulchellum), Cynara cardunculus var scolymus, Inula helenium (viscosa), Solenostema argel, Sesbania aegyptiaca (sesban), Cichorium intybus (pumilum), Cymbopogon proximus, Hemidesmus indicus, Rheum officinale, Cuminum cyminum, and combinations thereof. The invention further provides herbal compositions with antiviral properties comprising an extract from the leaves or seed of Sesbania aegyptiaca (sesban) and at least one additional herbal extract selected from the group consisting of seed of Nigella sativa, shoot of Cichorium intybus (pumilum), whole plant of Cymbopogon proximus, rhizome of Hemidesmus indicus, leaves of Solenostema argel, rhizome of Rheum officinale, and fruit of Ecballium elaterium.
    Type: Grant
    Filed: September 19, 2001
    Date of Patent: January 11, 2005
    Assignee: Zeyad Technologies LLC
    Inventors: Said I. A. Shalaby, Essam M. A. Hob Allah
  • Publication number: 20040265343
    Abstract: Materials with high levels of unsaponifiable matter, such as extracts from plants, result in Hydrolysates with unique properties. It has been found that the application of a hydrolysis process to materials, particularly materials with a high level of unsaponifiables (e.g., at least 6% by total weight of the material) produces a product with properties significantly different from those products resulting from the conventional saponification of materials with less than 6% by weight of unsaponifiables. The resulting Hydrolysates from the practice of the present invention are substantive, resisting both physical and aqueous-based removal from skin and hair, exhibit a very unique surfactant property, and are not foaming agents with water. Addition of extra alkali metal hydroxides to these Hydrolysates according to the present invention may thus be used to neutralized acidic gelling agents and thereby providing a gel with enhanced the performance for cosmetics and pharmaceuticals.
    Type: Application
    Filed: June 30, 2003
    Publication date: December 30, 2004
    Inventor: John C. Hill
  • Publication number: 20040259947
    Abstract: It is an object of the present invention to provide a glycerin fatty acid ester having an effect of mitigating the symptoms associated with the premenstrual syndromes (hereunder referred to as PMS) and excellent in the immediate effect as well as a drug for mitigating the symptoms associated with the PMS, a food or drink for mitigating the symptoms associated with the PMS, an edible fats and oils-containing composition for mitigating the symptoms associated with the PMS or the like, which comprise the glycerin fatty acid ester.
    Type: Application
    Filed: June 23, 2004
    Publication date: December 23, 2004
    Inventors: Shinji Seki, Yuuko Hirasawa, Miho Sakurada, Yuri Arai, Seiichi Shirasawa, Satoshi Negishi
  • Publication number: 20040258635
    Abstract: A class of UVA- and UVB-absorbing esters has been derived from milkweed oil by modification with a variety of cinnamic acids. These agents have the advantage of being synthesized from natural materials, while providing a value-added use for the oil. They are readily formulated into standard UV-absorbing daily-wear cosmetic, hair and skin care, and sunscreen formulations.
    Type: Application
    Filed: June 17, 2003
    Publication date: December 23, 2004
    Inventor: Rogers E. Harry-O'kuru
  • Publication number: 20040247619
    Abstract: A therapeutic herbal composition comprising Saw Palmetto, Bromelain, Willow Herb, Grape Seed Complex, Wild Rosella, Liquorice, Passionfruit Seed and Selenium Yeast is claimed. The composition may be used as a general health promotant but is also useful as a treatment of cancer and inflammation. Prostrate cancer and hyperplasia may be particularly beneficially addressed with the composition. The invention extends to a method of treatment using a composition as described.
    Type: Application
    Filed: July 27, 2004
    Publication date: December 9, 2004
    Inventor: Joanne Hambrook
  • Publication number: 20040241261
    Abstract: An active composition for treating skin containing: (a) an extract of grape seeds; (b) an extract of vine leaves; and (c) an extract of grape skins.
    Type: Application
    Filed: February 18, 2004
    Publication date: December 2, 2004
    Inventors: Santiago Rull Prous, Anna Granolleras Castello
  • Publication number: 20040241094
    Abstract: Oily paclitaxel composition and formulation for chemoembolization and preparation method thereof solubilizing paclitaxel in an oily contrast medium. The composition of the present invention solubilizes paclitaxel and has an advantage of delivering anticancer drug to the target cells by chemoembolization since it is possible to visualize the blood vessel during the chemoembolization process. The present invention also relates to oily paclitaxel composition and formulation additionally comprising chemicals that prevent paclitaxel precipitation for prolonged preservation and the preparation method thereof. Since the composition of the present invention solubilize paclitaxel effectively and can be visualized during chemoembolization, it can be used for TACE to treat hepatoma and other solid tumors.
    Type: Application
    Filed: March 11, 2004
    Publication date: December 2, 2004
    Inventors: Hesson Chung, Seo Young Jeong, Ick Chan Kwon, Yeong Taek Park, In Hyun Lee, Jae Hyung Park, Jin Wook Chung, Young man Kim
  • Publication number: 20040234628
    Abstract: A topical composition for the treatment of skin disorders such as scars containing at least one, preferably two select botanical oils alone or in combination with at least one other active agent and methods of using the same to treat skin disorders.
    Type: Application
    Filed: May 21, 2004
    Publication date: November 25, 2004
    Inventors: Marcy L. Kearns, Steven R. Strauss
  • Publication number: 20040228936
    Abstract: Cocoa extracts which include procyanidin monomers and their oligomers are useful in the modulation of inflammatory pathways, in the maintenance of the vascular health of a mammal and as an antibacterial treatment. The liquid or dry cocoa extracts can be included in foods, food supplements and pharmaceuticals for the inhibition of COX activity, the inhibition of LOX activity, the enhancement of nitric oxide production, the modulation of eicosanoids and endothelin, and the modulation of platelet activity.
    Type: Application
    Filed: February 17, 2004
    Publication date: November 18, 2004
    Applicant: Mars, Incorporated
    Inventors: Leo J. Romanczyk, Harold H. Schmitz
  • Publication number: 20040219188
    Abstract: This invention relates to compositions and methods for nutritional management of hepatic (liver) failure. In particular the invention is directed to a nutritionally complete formulation suitable for use as a supplement or total enteral feeding. The composition is specifically tailored to meet the requirements of hepatic patients in need of nutritional support. The composition comprises an organoleptically acceptable protein system designed to meet the altered metabolic needs of patients suffering from hepatic failure. The invention also relates to administering a nutritional composition comprising effective amounts of the branched-chain amino acids, valine, leucine, isoleucine, or mixtures thereof, and with or without a reduced amount of tyrosine, phenylalanine and tryptophan.
    Type: Application
    Filed: May 2, 2003
    Publication date: November 4, 2004
    Inventors: Gail M. Comer, Lucia Cheng, Vikkie Mustad, Yung-Sheng Huang, John McEwen, Stephen J. DeMichele, Bruce R. Bistrian, Gail M. Comer
  • Publication number: 20040219239
    Abstract: The present invention relates to the use of a composition comprising an oil with a high content of essential fatty acids of &ohgr;3 and &ohgr;6 type, preferably black current seed oil, and at least one compound selected from &bgr;-carotene, lycopene, tocopherol and its derivatives, tocotrienols and their derivatives, ascorbic acid and nicotinamide, as a nutritional supplement intended for preventing and/or combating the harmful effects of xenobiotics on the skin, in particular, on the skin's immune system.
    Type: Application
    Filed: May 27, 2003
    Publication date: November 4, 2004
    Inventors: Dominique Castelli, Nathalie Issachar
  • Patent number: 6811796
    Abstract: A method for prevention or therapy of pollen allergy, allergic rhinitis, atopic dermatitis, asthma or urticaria by administration of two kinds of crude drugs—seeds of Cucurbita moschata and flowers of Carthamus tinctorius—and at least one crude drug selected from Plantago asiatica, Lonicera japonica, Glycyrrhiza uralensis, Coix lachrymal-jobi var. ma-yuen, Zingiber officinale, Curcuma longa, Curcuma zedoaria and Artemisia argyi to a patient; and a health food for prevention, or improvement, or reduction of these symptoms containing the above substances.
    Type: Grant
    Filed: April 22, 2002
    Date of Patent: November 2, 2004
    Assignee: Matsuura Yakugyo Co., Ltd.
    Inventor: Satoshi Yoshida
  • Patent number: 6811795
    Abstract: Compositions having therapeutic value derived from plant material from one or more of Glinus lotoides, Ruta chalepensis, Hagenia abyssinica, and/or Millettia ferruginea are provided. The compositions are useful in treating and preventing cancer and other diseases. Methods of preparing such compositions and methods for treating patients by administering the compositions, either alone or with a pharmaceutical carrier or excipient, are provided.
    Type: Grant
    Filed: November 17, 1999
    Date of Patent: November 2, 2004
    Inventor: Tesfaye Zerihun Yigzaw
  • Patent number: 6805883
    Abstract: Foods and pharmaceuticals which contain cocoa and/or nut procyanidin(s) in combination with L-arginine are effective to induce a physiological increase in nitric oxide production in a mammal having ingested the product. A preferred food product is a confection, particularly a dark or milk chocolate containing nuts. The procyanidins may be natural or synthetic and may be provided by food ingredients such as chocolate liquor and/or cocoa solids prepared from underfermented beans and nut skins. The L-arginine may be natural or synthetic and may be provided by food ingredients such as nut meats, nut pastes, and/or nut flours, seeds, seed pastes, and/or seed flours, or gelatin. The beneficial health effects may include, for example, reduced blood pressure, resistance to cardiovascular disease, and anticancer activity.
    Type: Grant
    Filed: June 19, 2002
    Date of Patent: October 19, 2004
    Assignee: Mars, Incorporated
    Inventors: Kati A. Chevaux, Harold H. Schmitz, Leo J. Romanczyk, Jr.
  • Publication number: 20040202733
    Abstract: Novel food, dietary supplement and nutraceutical products containing phenol/protein complexes derived from vegetable sources have high antioxidant activity and very high levels of protein. The products provide novel means for administering high levels of plant antioxidants to human and mammals in the form of a protein concentrate. Due to their high antioxidant capacity these novel products are useful as aids in the prevention and treatment of many diseases.
    Type: Application
    Filed: April 28, 2004
    Publication date: October 14, 2004
    Inventors: Michael T. Yatcilla, Gilbert Gluck
  • Publication number: 20040202740
    Abstract: Annatto extract composition (AEC), including cis and trans geranyl geraniols (GG) and tocopherol-free C-5 unsubstituted tocotrienols (T3), increases the de novo synthesis of intermediate isoprenoid and distal protein products, including endogenous coenzyme Q10 (CoQ10), dolichols (DL) and all subsequent GG-prenylated and DL-glycosylated proteins, including GG-porphyrinated hemes. This intermediate and distal product replenishment by AEC reverses maladies of myotoxicity (of both drug and non-drug origins), including maladies that affect the muscle, kidney, eye, GI tract and skin, nerve, blood, and CoQ10-related syndromes of energetics and LDL protection. AEC anabolically increases the endogenous de novo CoQ10 synthesis via GG elongation/prenylation of side-chain and conversely CoQ10 catabolically increases the endogenous de novo GG synthesis via beta-oxidation of CoQ10. Also, such AEC decreases de novo synthesis and disposal of triglycerides (TG) in humans via PPAR activation and SREBP deactivation.
    Type: Application
    Filed: April 8, 2004
    Publication date: October 14, 2004
    Inventor: Barrie Tan
  • Publication number: 20040202738
    Abstract: This invention comprises methods and compositions of areca catechu. Methods of the present invention comprise extracting plant material of areca catechu so that compositions having characteristics different from those of native plant materials are obtained. Compositions comprising food aids and other dietary supplements are also taught.
    Type: Application
    Filed: April 5, 2004
    Publication date: October 14, 2004
    Inventors: Robert T. Gow, Brian Pierce, John Pierce, William Birdsall
  • Publication number: 20040202739
    Abstract: The present invention relates to compositions, articles of manufacture, methods of preparation thereof, methods of use thereof, etc., for enhancement of sexual pleasure, conditions, disorders, and diseases related to reproductive physiology and systems, especially of mammalian females. For instance, the present invention relates to all aspects of modulating the female sexual response, including female sexual dysfunction, such as female sexual arousal disorders (FSAD), orgasmic disorders, and sexual pain disorders, and enhancing female sexual pleasure and satisfaction of the female sexual experience. Accordingly, the present invention relates to compositions comprising botanical extracts, active agents, etc., which are useful to treat or affect any of the aforementioned conditions.
    Type: Application
    Filed: April 29, 2004
    Publication date: October 14, 2004
    Inventors: Martin G. Crosby, Robert M. Bennett
  • Patent number: 6803059
    Abstract: An anti-tumor pharmaceutical composition comprises the conjugation of Canavalia ensiformis-extracted protein with metal ions to form a metalloprotein complex for inhibiting the growth of tumor with enhanced activity and stability, but without toxicity.
    Type: Grant
    Filed: November 21, 2002
    Date of Patent: October 12, 2004
    Inventor: Sou-Yi Lu
  • Patent number: 6800303
    Abstract: A process of making a supplement for digestive ailment includes the steps of (a) soaking a raw composition which consists of 39.22% by weight of Radix Angelicae Sinensis, 39.22% by weight of Radix Paeoniae Alba, 3.92% by weight of Semen Arecae, 5.88% by weight of Talcum, 1.96% by weight of Radix Saussureae Lappae, 1.96% by weight of Semen Raphani, 3.92% by weight of Fructus Aurantii, and 3.92% by weight of Radix Glycyrrhizae, in a predetermined volume of water for a predetermined soaking time to form a pre-decocting solution and a pre-decocting composition; (b) heating said pre-decocting solution and said pre-decocting composition for a predetermined period of decocting time to form a mixture consisting of a residual composition and a supplement in solution; wherein a volume ratio of said supplement in solution and said water in the step (a) is approximately 1:3; and (c) separating said residual composition and said supplement in solution.
    Type: Grant
    Filed: July 16, 2002
    Date of Patent: October 5, 2004
    Inventor: Xiao-Feng Zuo
  • Publication number: 20040191341
    Abstract: The present invention is directed to methods and formulations for inhibiting Lipoxygenase or Lipoxygenase enzymes that function to biosynthesize or metabolize arachidonic acid into its intermediate Leukotriene constituents, as well as a method and formulation for treating and preventing inflammatory diseases and the symptoms associated with such diseases. The present invention methods and formulations effectively function as such through the introduction into the body (e.g. ingesting) a safe, pre-determined dosage of a naturaceutical composition formulated with or comprising one or more processed Morinda citrifolia products for a safe, pre-determined duration, wherein the processed Morinda citrifolia product may comprise one or more isolated active ingredients.
    Type: Application
    Filed: April 16, 2003
    Publication date: September 30, 2004
    Inventors: Afa Kehaati Palu, Brett West, Claude Jarakae Jensen, Chen Su, Bing-Nan Zhou, Stephen P. Story