Staphylococcus Patents (Class 424/93.42)
  • Publication number: 20150079131
    Abstract: The present invention regards use of a bacterial superantigen for administration onto the mucous membrane of a domestic non-human mammal for the prevention of inflammatory disorder, such as allergies, autoimmune and inflammatory diseases.
    Type: Application
    Filed: February 5, 2013
    Publication date: March 19, 2015
    Inventors: Ingegerd Adlerberth, Anna Rudin, Agnes Wold
  • Publication number: 20150079054
    Abstract: The present invention relates to a homeopathic formulation comprising dilutions of Arnica, Calendula, Echinacea, Hypericum, Silver, Sulfur, Thiosinaminum, Urtica, and methods for treating pain, inflammation, scar tissue, itching/pruritus and infection using same.
    Type: Application
    Filed: March 12, 2013
    Publication date: March 19, 2015
    Applicant: PRINCETON BIOTECHNOLOGY CORPORATION
    Inventor: Frank Demuro
  • Publication number: 20140294788
    Abstract: The present disclosure provides methods for enhancing muscle protein synthesis following physical exertion. In a general embodiment, a method for enhancing muscle protein synthesis following physical exertion is provided and includes administering to an individual a composition comprising from about 15 to about 35 g protein immediately following concurrent training. Programs for enhancing muscle adaptation resulting from concurrent training are also provided. The programs include providing a composition comprising from about 15 to about 35 g protein; and providing guidelines for consumption including a recommendation of the amount of the composition to consume immediately following concurrent training.
    Type: Application
    Filed: March 20, 2014
    Publication date: October 2, 2014
    Applicant: Nestec S.A.
    Inventors: David Mark BAILEY, Eric Scott ZALTAS, Daniel Ryan MOORE, Trent STELLINGWERFF
  • Publication number: 20140294787
    Abstract: Nutritional products having improved cohesiveness of food boluses and methods of making and using same are provided. The nutritional products may include nutritional compositions and high molecular weight, water-soluble polymers such that the nutritional products have extensional viscosities that provide improved cohesiveness to the nutritional products and Trouton ratios of at least 6. Methods of administering such nutritional products to patients having impaired swallowing ability and/or dysphagia are also provided.
    Type: Application
    Filed: March 1, 2012
    Publication date: October 2, 2014
    Inventors: Adam Stewart Burbidge, Jan Engmann, Simina Popa Nita
  • Patent number: 8784798
    Abstract: The present invention generally relates to the field of preventing and/or treating inflammatory and infectious disorders, in particular by boosting the endogenous antimicrobial defenses. One embodiment of the present invention is the use of B. longum NCC2705 (deposit number CNCM 1-2618) for use in the treatment or prevention of disorders related to the immune system including infections.
    Type: Grant
    Filed: May 7, 2010
    Date of Patent: July 22, 2014
    Assignee: Nestec S.A.
    Inventors: Valerie Petit, Clara Garcia-Rodenas, Monique Julita, Guenolee Prioult, Annick Mercenier, Sophie Nutten
  • Publication number: 20140065210
    Abstract: The present invention relates to a personal care product comprising a protein matrix wherein said protein matrix comprises at least one protein, at least one probiotic and a carrier fluid. The present invention also relates to the personal care product being a feminine care product particularly aimed at female urogenital health to treat or prevent vaginal infections. Oral and sinus infections, however, may also be benefited by the composition.
    Type: Application
    Filed: August 29, 2012
    Publication date: March 6, 2014
    Inventors: David W. Koenig, Neil T. Scholl, Vasily A. Topolkaraev, Amy L. Vanden Heuvel
  • Publication number: 20140056862
    Abstract: Nutritional compositions for maximizing muscle protein synthesis while minimizing the catabolism of muscle proteins and methods of using same are provided. In this manner, the nutritional compositions may provide for retention of lean body mass, which helps to avoid loss of independence and functionality, as well as to improve quality of life especially in the elderly at risk of sarcopenia and frailty. The nutritional compositions include ?-hydroxyisocaproic acid and ?-ketoglutarate. The composition may include other functional ingredients such as, but not limited to whey protein including whey protein micelles, prebiotic fibers, citrulline, eicosapentaenoic acid, L-carnitine, nucleotides, and amino acids. Methods of administering such nutritional products to individuals in need of same are also provided.
    Type: Application
    Filed: April 18, 2012
    Publication date: February 27, 2014
    Applicant: Nestec S.A.
    Inventors: Norman Alan Greenberg, Denis Breuille, Zamzam Kabiry (Fariba) Roughead, Doug Bolster, Jennifer Mager
  • Publication number: 20140056863
    Abstract: Nutritional compositions for maximizing muscle protein synthesis while minimizing the catabolism of muscle proteins and methods of using same are provided. In this manner, the nutritional compositions may provide for retention of lean body mass, which helps to avoid loss of independence and functionality, as well as to improve quality of life especially in the elderly at risk of sarcopenia and frailty. The nutritional compositions include ?-hydroxyisocaproic acid eicosapentaenoic acid. It may include other functional ingredients such as, but not limited to whey protein including whey protein micelles, prebiotic fibers, citrulline, ?-ketoglutarate, L-carnitine, nucleotides, and amino acids. Methods of administering such nutritional products to individuals in need of same are also provided.
    Type: Application
    Filed: April 18, 2012
    Publication date: February 27, 2014
    Applicant: Nestec S.A.
    Inventors: Norman Alan Greenberg, Denis Breuille, Zamzam kabiry (Fariba) Roughead, Doug Bolster, Jennifer Mager
  • Publication number: 20140044685
    Abstract: Nutritional compositions for maximizing muscle protein synthesis while minimizing the catabolism of muscle proteins and methods of using same are provided. In this manner, the nutritional compositions may provide for retention of lean body mass, which helps to avoid loss of independence and functionality, as well as to improve quality of life especially in the elderly at risk of sarcopenia and frailty. The nutritional compositions include ?-hydroxyisocaproic acid and citrulline. The composition may include other functional ingredients such as, but not limited to whey protein including whey protein micelles, prebiotic fibers, ?-keto-glutarate, eicosapentaenoic acid, L-carnitine, nucleotides, and amino acids. Methods of administering such nutritional products to individuals in need of same are also provided.
    Type: Application
    Filed: April 18, 2012
    Publication date: February 13, 2014
    Applicant: NESTEC S.A.
    Inventors: Norman Alan Greenberg, Denis Breuille, Zamzam Kabiry (Fariba) Roughead, Doug Bolster, Jennifer Mager
  • Publication number: 20140037602
    Abstract: Nutritional compositions for improving, treating and/or preventing various medical conditions and methods of using same are provided. The medical conditions may include allergies, autoimmune diseases, among others. The nutritional compositions include branched chain fatty acids and may include other functional ingredients such as, but not limited to probiotics, nucleotides and amino acids. Methods of administering such nutritional products to individuals in need of same are also provided.
    Type: Application
    Filed: April 12, 2012
    Publication date: February 6, 2014
    Applicant: NESTEC S.A.
    Inventors: Doug Bolster, Norman Alan Greenberg, Jennifer Mager, Zamzam Kabiry (Fariba) Roughead
  • Publication number: 20140037604
    Abstract: Nutritional compositions for maximizing muscle protein synthesis while minimizing the catabolism of muscle proteins and methods of using same are provided. In this manner, the nutritional compositions may provide for retention of lean body mass, which helps to avoid loss of independence and functionality, as well as to improve quality of life especially in the elderly at risk of sarcopenia and frailty. The nutritional compositions include ?-hydroxyisocaproic acid and may include other functional ingredients such as, but not limited to whey protein including whey protein micelles, prebiotic fibers, L-carnitine, nucleotides, and amino acids. Methods of administering such nutritional products to individuals in need of same are also provided.
    Type: Application
    Filed: April 18, 2012
    Publication date: February 6, 2014
    Applicant: NESTEC S.A.
    Inventors: Norman Alan Greenberg, Denis Breuille, Zamzam Kabiry (Fariba) Roughead, Doug Bolster, Jennifer Mager
  • Publication number: 20140037601
    Abstract: Nutritional compositions for improving, treating and/or preventing various medical conditions and methods of using same are provided. The medical conditions may include wounds, mucositis among others. The nutritional compositions include branched chain fatty acids and may include other functional ingredients such as, but not limited to probiotics, nucleotides and amino acids. Methods of administering such nutritional products to individuals in need of same are also provided.
    Type: Application
    Filed: April 12, 2012
    Publication date: February 6, 2014
    Applicant: NESTEC S.A.
    Inventor: Norman Alan Greenberg
  • Publication number: 20140030241
    Abstract: Nutritional compositions having dietary nucleotides, ?-3 fatty acids and citrulline are provided. The nutritional compositions may be formulated to improve T cell function, increase arginine availability in vivo, regulate myeloid-derived suppressor cells (“MDSC”), and decrease the risk and/or severity of infection after surgery or trauma. Methods of making, using and administering such nutritional compositions to individuals in need of same are also provided. Methods for modulating the affects of MDSC's are also provided.
    Type: Application
    Filed: March 15, 2012
    Publication date: January 30, 2014
    Applicant: NESTEC S.A.
    Inventor: Norman Alan Greenberg
  • Publication number: 20130336941
    Abstract: The present invention relates to methods for a ong-term and sustained release of flavonoids, in particular rhamnose-containing flavonoids, and for prolonging the uptake of said flavonoids in the gastro-intestinal tract. It further relates to compositions comprising said flavonoid and ?-rhamnosidase. It also encompasses compositions comprising hesperidin and hesperetin-7-gluoside.
    Type: Application
    Filed: March 15, 2013
    Publication date: December 19, 2013
    Inventors: Myriam Richelle, Gary . Williamson, Ivana Jankovic, Maarit Rein
  • Publication number: 20130129653
    Abstract: The present invention is directed toward protecting the cosmetic use of at least an effective amount of a lysate of at least one microorganism of the genus Bifidobacterium species, or a fraction thereof, for preventing and/or treating body odor.
    Type: Application
    Filed: April 22, 2011
    Publication date: May 23, 2013
    Applicant: L'OREAL
    Inventors: Isabelle Castiel, Audrey Gueniche, Dominique Bernard
  • Publication number: 20130089530
    Abstract: The invention relates to compositions for treating parasitic worm infections in a mammal. The composition includes an amount of intracellular components of lysed, beneficial, soil-inhabiting yeast cells sufficient to treat parasitic worm infections in a mammal; and/or an amount of whole or lysed soil-inhabiting bacteria cells, wherein the amount is sufficient to treat parasitic worm infections in a mammal, and optionally a pharmaceutically suitable carrier.
    Type: Application
    Filed: October 11, 2012
    Publication date: April 11, 2013
    Applicant: MICROBES, INC.
    Inventor: MICROBES, INC.
  • Patent number: 8338137
    Abstract: The invention relates to the type 5 and type 8 capsular polysaccharides produced by overproducing S. aureus strains, and also to the immunogenic compositions and the vaccines comprising said capsular polysaccharides.
    Type: Grant
    Filed: March 19, 2007
    Date of Patent: December 25, 2012
    Assignee: Sanofi Pasteur S.A.
    Inventors: Bachra Rokbi, Claude Meric, Noelle Mistretta, Philippe Talaga, Olivier Adam
  • Patent number: 8282943
    Abstract: The invention is relates to drugs on the basis of antibodies against non-cellular bone matrix proteins, especially BSP, for use in the prevention and treatment of bone metastases. According to the invention, the antibodies are induced in the patient by recombinantly expressing antigenic determinants of bone matrix proteins in Listeria and anchoring them on the surfaces thereof. The antigenic determinants are selected according to whether they are characteristic of antigens that are expressed by the tumor cells themselves.
    Type: Grant
    Filed: May 31, 2006
    Date of Patent: October 9, 2012
    Inventors: Ralf Jochem, Franz Paul Armbruster, Veit Braun, Christoph Von Eichel-Streiber
  • Publication number: 20120207726
    Abstract: The invention discloses biomarkers for human autism. The invention provides methods for treating, preventing, and diagnosing human autism and autism-related disorders.
    Type: Application
    Filed: December 16, 2011
    Publication date: August 16, 2012
    Applicant: THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK
    Inventors: W. Ian Lipkin, Mady Hornig, Brent L. Williams
  • Publication number: 20120189597
    Abstract: Nutritional compositions and methods of making and using the nutritional compositions are provided. In a general embodiment, the present disclosure provides a nutritional composition including one or more exogenous nucleotides.
    Type: Application
    Filed: August 9, 2010
    Publication date: July 26, 2012
    Applicant: NESTEC S.A.
    Inventors: Norman Alan Greenberg, Douglas Richard Bolster
  • Publication number: 20120156171
    Abstract: The invention relates to a cosmetic and/or dermatological topical composition, of particular use for the preventional and/or treatment of sensitive and/or dry skin, comprising an effective amount of at least one particularly probiotic microorganism and/or a fraction or metabolite thereof in combination with an effective amount of at least one polyunsaturated fatty acid and/or polyunsaturated fatty acid ester and/or a salt or derivative thereof in a physiologically-acceptable vehicle.
    Type: Application
    Filed: December 19, 2011
    Publication date: June 21, 2012
    Applicants: NESTEC S.A., L'OREAL
    Inventors: Lionel BRETON, Roland JOURDAIN, Audrey GUENICHE, Isabelle BUREAU-FRANZ, Mathilde FLEITH, Armand MALNOE
  • Patent number: 8187585
    Abstract: The present invention relates to a composition comprising at least one fibronectin binding protein, and/or at least one a truncated fibronectin binding protein and/or at least one fibronectin binding peptide, all comprising at least one fibronectin binding domain; and at least one iscom matrix complex and/or liposome and/or at least one lipid and at least one saponin, whereby the at least one lipid and the at least one saponin may be in complex, solution or suspension. Further, it regards use thereof for the preparation of a vaccine against a micro organism that comprises at least one fibronectin binding domain. It also relates to a kit of parts comprising at least two compartments, wherein one compartment comprises at least one truncated fibronectin binding protein and/or a fibronectin binding peptide, that comprises at least one fibronectin binding domain, and another compartment comprises an instruction for use and/or an iscom matrix complex and/or an iscom complex and or a liposome.
    Type: Grant
    Filed: July 20, 2011
    Date of Patent: May 29, 2012
    Assignee: Isconova AB
    Inventors: Bror Morein, Karin Lövgren Bengtsson, Jill Ekstrom, Katarina Ranlund, Birgitta Fromgren, Carlos Concha Bascunan
  • Publication number: 20120107395
    Abstract: Soft gel capsules are formed from an outer gelatin-containing shell and a filling. The filling includes a probiotic and a dessicant.
    Type: Application
    Filed: December 7, 2010
    Publication date: May 3, 2012
    Applicant: VIVA PHARMACEUTICAL INC.
    Inventors: Xueju Xie, Jason Jiang-Chung Ko
  • Patent number: 8071088
    Abstract: Compositions and methods useful for reducing or eliminating the presence of pathogens in meat and meat products are disclosed. Administration of one or more lactic acid producing microorganisms to a live animal, to a carcass, to meat, to meat products, or in animal feed results in significant reductions in the amount of pathogens potentially harmful to humans when ingested. Synergistic effects can be achieved with the administration of multiple strains of microorganisms.
    Type: Grant
    Filed: August 22, 2007
    Date of Patent: December 6, 2011
    Assignee: Guardian Food Technologies, LLC
    Inventors: Bryan E. Garner, Douglas R. Ware
  • Publication number: 20110256115
    Abstract: The invention relates to [6)O-?-D-Glcp-(1?]n-6-O-?-D-Glcp-(1?-phenolic derivatives. These [6)O-?-D-Glcp-(1?]n-6-O-?-D-Glcp-(1?-phenolic derivatives of selected phenolics are new, have a solubility in water higher than that of their parent O-?-D-Glcp-(1?-phenolic derivatives and have useful applications in cosmetic, nutrition and pharmaceutical compositions, such as treating or preventing oxidative stress, a cancer, a cardiovascular disease, a bacterial infection, a viral infection, a fungal infection, a UV-induced erythema, an allergy, a metabolism disorder, diabetes, an obesity, a hormonal disorder, a bone disease, a pain, a brain disease, a mouth or teeth disease, an inflammatory or immune disorder.
    Type: Application
    Filed: December 22, 2009
    Publication date: October 20, 2011
    Applicant: Libragen
    Inventors: Daniel Auriol, Aurélien Ginolhac, Fabrice Lefevre, Renaud Nalin
  • Publication number: 20110223137
    Abstract: The present invention relates to compositions for use in low-birth weight infants. In particular, the compositions are probiotic compositions which are used for achieving full enteral feeding in low birth weight infants. The invention is also concerned with the use of specific probiotics in the manufacture of low-birth weight infant formulations.
    Type: Application
    Filed: November 23, 2009
    Publication date: September 15, 2011
    Applicant: NESTEC S.A.
    Inventors: Dominique Darmaun, Marie-Claire Fichot, Hugues Piloquet, Florence Rochat, Carole Rouge, Jean-Christophe Roze
  • Publication number: 20110104240
    Abstract: The present disclosure provides a device having a casing with a barrier surface and a contact surface and a composition in the casing having a nitric oxide precursor and an isolated enzyme or live cell expressing an endogenous enzyme, for converting the nitric oxide gas precursor to nitric oxide gas or having activity on a substrate that produces a catalyst that causes the conversion of the nitric oxide gas precursor to nitric oxide gas. The present disclosure also provides methods and uses for treating wounds, microbial infections and dermatological disorders and for preserving meat products.
    Type: Application
    Filed: June 23, 2009
    Publication date: May 5, 2011
    Applicant: Micropharma Limited
    Inventors: Mitchell Lawrence Jones, Satya Prakash
  • Publication number: 20110052538
    Abstract: This invention pertains to a method of promoting gastrointestinal health by ingesting a composition comprising one or more probiotic microorganisms, one or more carbohydrate sources, and one or more resistant protein products. Large intestinal health is benefited by one or more of the following: increased fecal weight, lower fecal pH, increased carbohydrate fermentation, and amelioration of protein fermentation.
    Type: Application
    Filed: October 18, 2010
    Publication date: March 3, 2011
    Applicant: BRUNOB II B.V.
    Inventors: Ian Lewis Brown, Anne M. Birkett, Richard Le Leu, Graeme P. Young
  • Publication number: 20110008303
    Abstract: Described herein are methods for treating and preventing MRSA/MSSA. The present subject matter deviates from current treatment methods by introducing a controlled decolonization/recolonization method, which eradicates the host surface area of MRSA/MSSA, and colonizes the newly cleared surface area with a nonpathogenic or pathogenic bacteria capable of out-competing MRSA/MSSA.
    Type: Application
    Filed: March 12, 2009
    Publication date: January 13, 2011
    Applicant: CEDARS-SINAI MEDICAL CENTER
    Inventor: George Y. Liu
  • Publication number: 20100278793
    Abstract: The present invention relates to the cosmetic treatment of greasy skin and/or skin that tends to be greasy with a lysate of at least one microorganism of the genus Bifidobacterium species and/or a fraction thereof, as an active.
    Type: Application
    Filed: October 28, 2009
    Publication date: November 4, 2010
    Applicant: L'OREAL
    Inventors: Audrey Gueniche, Isabelle Castiel, Dominique Bernard
  • Publication number: 20100215626
    Abstract: The MRSA Decolonization Kit, or MDK, is a unique process available in a single kit to eliminate MRSA from individuals who have recently suffered an invasive infection from the potentially deadly bacteria and strengthen their body's ability to prevent recurrent infection. The kit provides patients with everything they need to remove MRSA from their skin flora and replace it with a far less dangerous bacteria, Staphylococcus Epidermidis. The kit has detailed instructions on using the bactericidal ointments and cleansers followed by the application of Sepiderm Lotion that contains viable, healthy Staphylococcus Epidermidis. It also includes detailed instructions on ridding the home environment of the dangerous bacteria as well as the vital component of personal hygiene to minimize repeat contamination with the bacteria.
    Type: Application
    Filed: February 25, 2009
    Publication date: August 26, 2010
    Inventor: Brian Patrick Murphy
  • Publication number: 20100166708
    Abstract: The disclosure provides methods and compositions useful for treating microbial and viral infections. In certain aspects, the compositions and methods relate to the use of an effective amount of a delta-haemolysin and/or phenol soluble modulin-delta or functional variant thereof. In other aspects, the compositions and methods relate to the use of an effective amount of Staphylococcus epidermidis or an extract of 5. epidermidis comprising delta-haemolysin and/or phenol soluble modulin-delta or functional variant thereof.
    Type: Application
    Filed: February 20, 2008
    Publication date: July 1, 2010
    Applicant: THE REGENTS OF THE UNIVERSITY OF CALIFORNIA
    Inventors: Richard L. Gallo, Victor Nizet, Anna Cogen, YuPing Lai
  • Publication number: 20100150890
    Abstract: It is intended to provide a safe composition for preventing or treating obesity or related complications which has an autonomic nervous control effect, in particular, an effect of enhancing sympathetic nervous activity and an effect of promoting energy metabolism. Thus, a medicinal composition, a food or a drink containing 2,3-dihydro-3,5-dihydroxy-6-methyl-4H-pyran-4-one and having an autonomic nervous control effect and an effect of promoting energy metabolism is provided.
    Type: Application
    Filed: March 28, 2008
    Publication date: June 17, 2010
    Applicant: SUNTORY HOLDINGS LIMITED
    Inventors: Yoshinori Beppu, Nobuo Tsuruoka, Tomohiro Rogi, Hajime Komura, Katsuya Nagai
  • Publication number: 20100116268
    Abstract: The invention relates to aqueous aerosol preparations for inhalation, containing therapeutically active micro-organisms or parts of micro-organisms as the active ingredient.
    Type: Application
    Filed: April 29, 2008
    Publication date: May 13, 2010
    Applicant: BOEHRINGER INGELHEIM INTERNATIONAL GMBH
    Inventors: Georg Boeck, Michael Spallek
  • Publication number: 20100092439
    Abstract: Antimicrobially-primed medicinal maggots and therapy methods are described for the treatment of a variety of indications including, without limitation, infected or non-healing wounds, soft tissue infection and the like (e.g., gangrenous or infected wound).
    Type: Application
    Filed: July 20, 2009
    Publication date: April 15, 2010
    Applicant: MONARCH LABS LLC
    Inventor: Ronald A. Sherman
  • Publication number: 20100055081
    Abstract: The present invention relates to methods for a long-term and sustained release of flavonoids, in particular rhamnose-containing flavonoids, and for prolonging the uptake of said flavonoids in the gastro-intestinal tract. It further relates to compositions comprising said flavonoid and ?-rhamnosidase. It also encompasses compositions comprising hesperidin and hesperetin-7-glucoside.
    Type: Application
    Filed: August 22, 2007
    Publication date: March 4, 2010
    Applicant: NESTEC S.A.
    Inventors: Myriam Richelle, Gary Williamson, Ivana Jankovic, Maarit Rein
  • Patent number: 7648830
    Abstract: A method is provided for determining the presence of a target bacteria based on its resistance to a cell lysing antibiotic. Said antibiotic is used to lyse cells of non-target bacteria in a sample and hence facilitate isolation of the target prior to detection by known means.
    Type: Grant
    Filed: September 2, 2002
    Date of Patent: January 19, 2010
    Assignee: The Secretary of State for Defence in Her Britannic Majesty's Government of the United Kingdom of Great Britain and Northern Ireland
    Inventors: David James Squirrell, Rachel Louise Leslie, Kevin J Bown
  • Publication number: 20090081173
    Abstract: Disclosed are methods of increasing the virulence of a bacteriophage, comprising contacting a bacteriophage with a composition comprising a bacterium or bacterial extract; and a polymer. Also disclosed are methods of propagating and isolating therapeutic bacteriophages that involve use of dilute polymer compositions. Also disclosed are pharmaceutical compositions the bacteriophage for which virulence has been increased by the methods set forth herein or which have been isolated by the methods set forth herein.
    Type: Application
    Filed: August 8, 2008
    Publication date: March 26, 2009
    Inventor: Philip Serwer
  • Publication number: 20090068161
    Abstract: The cosmetic use of at least an effective amount of hesperidin or of one of its derivatives in combination with at least an effective amount of at least one microorganism, in particular probiotic microorganism, or one of its fractions as agent for preventing a reduction in and/or for reinforcing the barrier function of the skin.
    Type: Application
    Filed: September 4, 2008
    Publication date: March 12, 2009
    Applicants: L'OREAL, NESTEC S.A.
    Inventors: Audrey GUENICHE, Isabelle CASTIEL
  • Publication number: 20090068160
    Abstract: Cosmetic use of an effective amount of at least one lysate of at least one microorganism of the genus Bifidobacterium species and/or a fraction thereof, for preventing and/or treating a skin disorder in the case of sensitive skin.
    Type: Application
    Filed: August 28, 2008
    Publication date: March 12, 2009
    Applicant: L'OREAL
    Inventors: Isabelle CASTIEL, Lionel BRETON, Audrey GUENICHE
  • Publication number: 20090022700
    Abstract: The present invention relates to a composition which is in the form of a water-soluble anhydrous film comprising at least one water-soluble or water-dispersible film-forming polymer, and at least one live, in particular probiotic, microorganism. It also relates to a kit containing such a composition, as a combination with a secondary composition.
    Type: Application
    Filed: April 23, 2008
    Publication date: January 22, 2009
    Applicant: L'OREAL
    Inventors: Guillaume Cassin, Jean-Thierry Simonnet
  • Publication number: 20080305089
    Abstract: The present invention relates to a pharmaceutical composition which includes naturally occurring, non-transgenic isolated bacteria from the group of Lactococcus and Acinetobacter or fragments thereof or mixtures thereof, to such a bacterium as a medicament for the prevention and/or treatment of allergic or chronic inflammatory disorders and to a process for producing this composition.
    Type: Application
    Filed: March 3, 2008
    Publication date: December 11, 2008
    Applicant: Protectimmun GmbH
    Inventors: Albrecht Bufe, Otto Holst, Harald Renz, Erika von Mutius, Johann Bauer, Nicole Blumer, Jennifer Debarry, Markus Ege, Susanne Friedrich, Holger Garn, Soren Gatermann, Anna Hanuszkiewicz, Holger Heine, Michael Wegmann
  • Publication number: 20080254009
    Abstract: The invention includes a method of treating gastrointestinal diseases associated with species of genus Clostridium such as clostridium deficit in human patients with gastrointestinal disorders having an etiological component such as a microbial agent producing a toxin where treated with an antimicrobial composition an amount effective to inhibit or eliminate the microbial agent. The antimicrobial composition in a form of probiotic mixture can be administrated alone or in combination with an antimicrobial agent, such as a bacteriophage which is specific for a bacterium producing toxin or antibiotics which are then used to eliminate or inhibit the clostridial species overgrown in a patient's gastrointestinal tract. Disorders that can be treated by the method of the invention include diarrhea or inflammatory bowel diseases such as colitis or Crohn's disease.
    Type: Application
    Filed: October 30, 2007
    Publication date: October 16, 2008
    Inventor: Sydney M. Finegold
  • Publication number: 20080219960
    Abstract: The current invention provides methods and means for heterologous expression, production and/or secretion of complex capsular polysaccharides in non-pathogenic, non-invasive Gram-positive bacteria. The invention in particular provides non-pathogenic, non-invasive Gram-positive bacteria capable of expression and/or secretion of heterologous, complex polysaccharides from a pathogenic bacterial species. Such bacteria and polysaccharides produced therein may be applied according to the invention to provide compositions for vaccination for the treatment and prevention of infectious bacterial diseases.
    Type: Application
    Filed: December 16, 2005
    Publication date: September 11, 2008
    Inventors: Masja Nathalie Nierop Groot, Willem Meindert De Vos, Michiel Kleerebezem
  • Publication number: 20080206211
    Abstract: Composition containing a conditioned cell culture medium or an extract thereof, said medium being able to be obtained by contact with at least one culture of digestive tract cells and at least one probiotic microorganism. It also relates to the use of conditioned culture medium for improving skin homeostasis, etc.
    Type: Application
    Filed: February 26, 2008
    Publication date: August 28, 2008
    Applicant: L'OREAL
    Inventor: Audrey GUENICHE
  • Publication number: 20080199445
    Abstract: The present invention relates to methods and compositions for treatment of microbial infections and for the enhancement of resistance to infection. The invention comprises administration of an effective amount of bacterial lysate compositions for the treatment of pathological conditions of microbial infections. The present invention can also be used to enhance the immune system to prevent infections by the administration of an effective amount of the compositions.
    Type: Application
    Filed: February 11, 2008
    Publication date: August 21, 2008
    Inventors: Jiri Pillich, John C. Balcarek
  • Patent number: 7067135
    Abstract: The invention features methods and compositions for treatment or prevention of infection by, or disease caused by infection with, Staphylococcus spp., particularly S. aureus.
    Type: Grant
    Filed: April 19, 2001
    Date of Patent: June 27, 2006
    Inventor: Naomi Balaban
  • Patent number: 6984381
    Abstract: A novel vaccine for immunizing animals against Staphylococcus aureus-induced mastitis is disclosed. The vaccine is comprised of whole killed cells of S. aureus in a dosage effective to immunize an animal against the organism, in combination with a pharmaceutically acceptable carrier.
    Type: Grant
    Filed: July 5, 2002
    Date of Patent: January 10, 2006
    Assignee: The United States of America as represented by the Secretary of Agriculture
    Inventors: Albert Guidry, Celia O'Brien
  • Patent number: 6846625
    Abstract: The invention comprises methods useful within a larger process for identifying compounds and/or designing further compounds with activity to produce a desired phenotype (for example, growth inhibition) in cells whose target cell component is the subject of certain studies to identify such compounds. The invention employs constructed cells comprising a regulable gene encoding a biomolecule which modulates (inhibits or activates) in vivo the function of a target component of the cell which can be an enzyme for example. The process incorporates methods for identifying biomolecules that bind to a chosen target cell component in vitro, methods for identifying biomolecules that also bind to the chosen target and modulate its function intracellularly, causing a phenotypic effect.
    Type: Grant
    Filed: January 8, 1999
    Date of Patent: January 25, 2005
    Assignee: Cubist Pharmaceuticals, Inc.
    Inventors: Francis P. Tally, Jianshi Tao, Philip A. Wendler, Gene Connelly, Paul L. Gallant
  • Patent number: 6790448
    Abstract: Isolated peptide sequences and proteins containing these sequences are provided which are useful in the prevention and treatment of infection caused by Gram-positive bacteria. The peptide sequences have been shown to be highly conserved motifs in the surface proteins of Gram-positive bacteria, and these consensus sequences include amino acid sequences such as LPXTG (SEQ ID NO:13), ALKTGKIDIIISGMTSTPERKK (SEQ ID NO:14), VEGAWEKPVAEAYLKQN (SEQ ID NO:15), and EYAGVDIDLAKKIAK (SEQ ID NO:16). By virtue of the highly conserved regions, the sequences and the proteins including these sequences can be utilized to generate antibodies which can recognize these highly conserved motifs and the proteins containing them and thus be useful in the treatment or prevention of a wide range of infections caused by Gram-positive bacteria.
    Type: Grant
    Filed: May 8, 2002
    Date of Patent: September 14, 2004
    Assignee: The Texas A&M University System University
    Inventors: Yi Xu, Magnus A. O. Hook