Streptococcus Patents (Class 424/93.44)
  • Patent number: 10314867
    Abstract: The present invention relates to a composition comprising Bifidobacterium bacteria for use for reducing intestinal gas production in an individual.
    Type: Grant
    Filed: April 23, 2015
    Date of Patent: June 11, 2019
    Assignee: COMPAGNIE GERVAIS DANONE
    Inventors: Boris Le Neve, Émilie Rocher, Denis Guyonnet
  • Patent number: 10238597
    Abstract: The present invention teaches compositions, methods and kits for treating skin conditions, including dandruff. In various embodiments, the compositions include an effective amount of one or more probiotic microorganism of vaginal origin and/or a fraction thereof and/or a component of the metabolome for preventing and/or treating skin disorders of the scalp.
    Type: Grant
    Filed: November 17, 2016
    Date of Patent: March 26, 2019
    Assignee: BEAUTY BIOLABS LLC
    Inventors: Marc M. Baum, Janelle M. Baum
  • Patent number: 10159708
    Abstract: A composition for the treatment of acne is provided. The composition includes fermentation products of leuconostoc bacterium. A method for the treatment of acne using the composition is also provided.
    Type: Grant
    Filed: February 3, 2017
    Date of Patent: December 25, 2018
    Assignee: Active Micro Technologies, LLC
    Inventors: Durant Scholz, Erica Segura
  • Patent number: 10145853
    Abstract: The present invention aims to present methods to detect nonalcoholic fatty liver disease including nonalcoholic steatohepatitis by using a protein or its partial peptide that differs in presence or absence, or in quantity between healthy human subjects and patients with nonalcoholic fatty liver disease or nonalcoholic steatohepatitis or between patients with fatty liver and nonalcoholic steatohepatitis and further aims to present biomarkers comprising said protein and said partial peptide to be used to detect nonalcoholic fatty liver disease including nonalcoholic steatohepatitis. Specifically, 35 kDa protein fragment consisting of amino acid sequence expressed by Sequence No. 2 and its partial peptide consisting of amino acid sequence expressed by Sequence No. 3 (including its glycated form) of inter-alpha-trypsin inhibitor heavy chain H4 precursor consisting of amino acid sequence expressed by Sequence No.
    Type: Grant
    Filed: April 6, 2015
    Date of Patent: December 4, 2018
    Assignee: MCBI, Inc.
    Inventors: Kohji Meno, Hideaki Suzuki
  • Patent number: 10039798
    Abstract: Provided are process of regulating expression of one or more genes or proteins involved in circadian rhythm. A subject such as a cell is administered or contacted to an extract of rosemary, an extract of hemerocallis fulva, or combinations thereof, optionally provided as a component of a dietary supplement. The presence of one or more active agents in the extracts administered at a targeted administration time alters the expression of one or more genes or proteins involved in circadian rhythm, illustratively CLOCK, BMAL1, FBXL3, FBXL21, or SIRT1.
    Type: Grant
    Filed: November 13, 2014
    Date of Patent: August 7, 2018
    Assignee: IN Ingredients, Inc.
    Inventors: Bolin Qin, Augustin T. Romero, Tim Romero
  • Patent number: 9999647
    Abstract: The invention relates to a method for obtaining a composition from a plant extract, to assist in the treatment or prevention of disorders or diseases related to neovascularisation.
    Type: Grant
    Filed: December 17, 2015
    Date of Patent: June 19, 2018
    Assignees: Ethnodyne, Centre National De La Recherche Scientifique (CNRS)
    Inventors: Chérif Rabhi, Léon Cariel, Jamal Ouanzzani, Guillaume Arcile
  • Patent number: 9999640
    Abstract: Microencapsulated probiotic bacteria protected from degradation by acidic aqueous solutions, high bile salt concentrations, elevated temperatures, and prolonged storage and having an increased anti-bacterial activity as compared to their non-microencapsulated counterparts. The microencapsulated probiotic bacteria comprise probiotic bacteria encapsulated in microcapsules. The probiotic bacteria comprise live Lactobacillus plantarum cells. Each of the microcapsules comprises a matrix of a gelled alginate. The matrix wholly envelops the probiotic bacteria within the matrix. An outer surface of the matrix has a coating consisting essentially of one vegetable oil selected from the group consisting of olive oil and canola oil, or an outer surface of the matrix is treated with sodium chloride. The microencapsulated probiotic bacteria have an average particle size of less than 1000 microns (?m) in diameter.
    Type: Grant
    Filed: February 2, 2016
    Date of Patent: June 19, 2018
    Assignee: University of Dammam
    Inventor: Lulwah Yousef Abdullateef Al-Furaih
  • Patent number: 9962351
    Abstract: Disclosed is a new function of a small molecule metabolite glutamine. The small molecule can improve sensitivity of bacteria including antibiotic-resistant bacteria to antibiotics. Also disclosed is an application of glutamine in combination with glucose in improving sensitivity of bacteria to antibiotics.
    Type: Grant
    Filed: December 4, 2012
    Date of Patent: May 8, 2018
    Assignee: SUN YAT-SEN UNIVERSITY
    Inventors: Xuanxian Peng, Hui Li, Xianliang Zhao
  • Patent number: 9428551
    Abstract: The present invention provides novel therapeutic antimicrobial peptides that are bactericides and have an inhibitory effect on biofilms produced by biofilm-forming bacteria and especially biofilm-forming Staphyloccocal bacteria. The invention includes the nucleic acids encoding the polypeptides, methods of treating bacterial infections, medical devices or implants or prosthetics impregnated with, covered or coated in the polypeptides, and means of delivery of the peptide to the oral cavity.
    Type: Grant
    Filed: May 15, 2014
    Date of Patent: August 30, 2016
    Assignee: The University of Manchester
    Inventors: Mathew Upton, Stephanie Sandiford
  • Patent number: 9301983
    Abstract: Present invention features a novel use of Lactobacillus for treating type 2 diabetes, wherein the Lactobacillus is Lactobacillus reuteri GMNL-89 with the deposition numbers of BCRC 910340 and CCTCC M 207154 and comprises of live, dead bacteria or supernatant of the bacterial culture(s) and a pharmaceutically acceptable vehicle. The invention also discloses the efficacies of the indicated Lactobacillus strain including anti-oxidative enzyme activity, anti-inflammation, reduction of blood glucose level, reduction of triglycerides, reduction of total cholesterol, reduction of LDL, increase of HDL and improve insulin utilization.
    Type: Grant
    Filed: March 7, 2014
    Date of Patent: April 5, 2016
    Assignee: GenMont Biotech Inc.
    Inventors: Hui-Yu Huang, Yi-Hsing Chen, Feng-Ching Hsieh
  • Patent number: 9079935
    Abstract: A method of treating a patient to reduce risk of developing Clostridium difficile-associated disease or reducing existing Clostridium difficile-associated disease in a mammalian subject involves administering to a mammalian subject an effective amount of a germination-inhibiting compound derived from taurocholate. Novel compounds of this class are also provided.
    Type: Grant
    Filed: August 8, 2013
    Date of Patent: July 14, 2015
    Assignee: The Board of Regents of the Nevada System of Higher Education on Behalf of The University of Nevada, Las Vegas
    Inventors: Ernesto Abel-Santos, Amber Howerton
  • Patent number: 9040037
    Abstract: The present invention provides a triple vital bacteria composition, including: powder of Bifidobacterium longum, powder of Lactobacillus acidophilus, and powder of Streptococcus faecalis. The present invention further provides a method for preparing the above triple vital bacteria composition, as well as the protection agents, the fermenting culture medium and the seed culture medium used therein.
    Type: Grant
    Filed: February 3, 2008
    Date of Patent: May 26, 2015
    Assignee: Shanghai Sine Pharmaceutical Laboratories Co., Ltd.
    Inventors: Binhua Chen, Xuesong Wang, Liang Zhang
  • Publication number: 20150139968
    Abstract: The present invention relates to a composition used for treating picornavirus infection comprising at least one of the following bacterial strains: Lactobacillus paracasei GMNL-33 with the deposition numbers of CCTCC M 206133, Lactobacillus reuteri GMNL-89 with the deposition numbers of CCTCC M 207154 and Lactobacillus casei GMNL-277 with the deposition numbers of CCTCC M 2013197, and a pharmaceutically acceptable vehicle. The Lactobacillus casei GMNL-277 of the invention is a novel Lactobacillus isolated strain. In addition, the present invention also features the novel use of the composition of the Lactobacillus strains for treating picornavirus infection, and the mechanism of which is inhibition of virus infection by binding of the probiotic bacteria to viruses.
    Type: Application
    Filed: November 15, 2013
    Publication date: May 21, 2015
    Applicant: GENMONT BIOTECH INC.
    Inventors: Ya-Fang Wang, Jen-Ren Wang, Yi-Hsing Chen
  • Publication number: 20150098929
    Abstract: A probiotic organism which is capable of proliferation in iron-rich media, an environment which is generally unfavourable to probiotic organisms, is described.
    Type: Application
    Filed: July 19, 2012
    Publication date: April 9, 2015
    Applicant: THE UNIVERSITY OF BRISTOL
    Inventors: Tristan Cogan, Jenny Bailey
  • Publication number: 20150079131
    Abstract: The present invention regards use of a bacterial superantigen for administration onto the mucous membrane of a domestic non-human mammal for the prevention of inflammatory disorder, such as allergies, autoimmune and inflammatory diseases.
    Type: Application
    Filed: February 5, 2013
    Publication date: March 19, 2015
    Inventors: Ingegerd Adlerberth, Anna Rudin, Agnes Wold
  • Publication number: 20150079055
    Abstract: An individual at risk for necrotizing enterocolitis and related disorders can be identified by measuring the level of at least one secretor antigen in a biological sample from the individual and comparing the measured level of the at least one secretor antigen to a predetermined value or a predetermined range of values. Among the secretor antigens which can be measured are: the H-1, H-2, Lewisb and Lewisy antigens and derivatives thereof (e.g., a sialylated form of Lewis a, Lewis x, Lewis b, Lewis y; H-1, H-2, Lewis a, Lewis x, Lewis b or Lewis y).
    Type: Application
    Filed: September 23, 2014
    Publication date: March 19, 2015
    Applicants: Children's Hospital Medical Center, The General Hospital Corporation, Instituto Nacional de Ciencias Medicas Y Nutricion
    Inventors: Ardythe L. Morrow, David S. Newburg, Guillermo M. Ruiz-Palacios
  • Publication number: 20150079056
    Abstract: The present invention relates to the field of infant cereals. In particular, the present invention relates to the field of infant cereals that can be used to strengthen the immune system of the infant and/or that can be used to treat or prevent inflammatory disorders. For example these benefits can be provided by probiotic micro-organisms. An embodiment of the present invention relates to an infant cereal comprising non-replicating probiotic-micro-organisms, for example bioactive heat treated probiotic micro-organisms.
    Type: Application
    Filed: November 21, 2014
    Publication date: March 19, 2015
    Inventors: Annick Mercenier, Sophie Nutten, Guenolee Prioult
  • Patent number: 8968726
    Abstract: Compositions are described which contain lactoferrin and angiogenin. The described compositions are useful in treatment of a variety of conditions, particularly in promoting bone health and relief of menopausal symptoms.
    Type: Grant
    Filed: August 5, 2011
    Date of Patent: March 3, 2015
    Assignee: Naidu LP
    Inventors: A. Satyanarayan Naidu, A. G. Tezus Naidu, A. G. Sreus Naidu
  • Patent number: 8968721
    Abstract: The disclosure relates to a solid glass matrix of polysaccharides, monossaccharides or disaccharides in combination with polyols as delivery vehicles for preservation and post gastric administration of a probiotic. The delivery vehicle is capable of releasing the probiotic at their site of action. The present invention further includes methods of making and using the solid glass matrix delivery vehicle of the invention.
    Type: Grant
    Filed: April 30, 2012
    Date of Patent: March 3, 2015
    Assignee: Advanced BioNutrition Corporation
    Inventor: Mordechi Harel
  • Patent number: 8961952
    Abstract: The present invention generally relates to the field of probiotic micro-organisms, in particular to the field of non-replicating probiotic micro-organisms. Embodiments of the present invention relate to compositions comprising probiotic micro-organisms that were rendered non-replicating by extrusion. Such compositions may be used to treat or prevent disorders that are related to a compromised immune system.
    Type: Grant
    Filed: November 11, 2011
    Date of Patent: February 24, 2015
    Assignee: Nestec S.A.
    Inventors: Annick Mercenier, Antoine Wermeille, Audrey Demont, Guenolee Prioult
  • Patent number: 8962689
    Abstract: The present invention relates in general to medium chain dicarboxylic acids, their derivatives and their uses. In particular, the present invention relates to a composition comprising medium chain dicarboxylic acids and to the use of medium chain dicarboxylic acids and their derivatives for the preparation of products to treat or prevent metabolic disorders. The composition of the present invention can particularly well be used to treat or prevent hyperglycemia, for example diabetes.
    Type: Grant
    Filed: March 9, 2009
    Date of Patent: February 24, 2015
    Assignee: Nestec S.A.
    Inventors: Geltrude Mingrone, Catherine Mace
  • Publication number: 20150044146
    Abstract: The invention provides recombinant Streptococcus mutans strains that can be used to improve oral health. An embodiment of the invention provides a method of reducing the incidence or severity of dental caries in a dental caries-susceptible host comprising administering orally to the host an isolated recombinant S. mutans strain of the invention in an amount effective for replacement of dental caries-causing S. mutans host strains in the oral cavity of the host. The isolated recombinant S. mutans strain 10 can be contained in a mouthwash, toothpaste, chewing gum, floss, chewable tablet, food, or beverage.
    Type: Application
    Filed: February 22, 2013
    Publication date: February 12, 2015
    Inventors: Jeffrey D. Hillman, James Leif Smith, Shawanda R. Wilson-Stanford
  • Patent number: 8945533
    Abstract: The object of the present invention is to provide an oral cavity composition which is nontoxic, excellent in plaque control, can prevent or treat onset of caries and periodontal disease caused by oral pathogens as well as can prevent or eliminate bad breath. The invention provides an oral cavity composition containing a lactic acid bacterium, Streptococcus faecalis as an active ingredient, the oral cavity composition wherein the lactic acid bacterium, Streptococcus faecalis is Streptococcus faecalis WB2000 strain and the oral cavity composition which is a non-aqueous oral cavity composition.
    Type: Grant
    Filed: November 14, 2006
    Date of Patent: February 3, 2015
    Assignees: Nippon Zettoc Co., Ltd., Wakamoto Pharmaceutical Co., Ltd.
    Inventors: Keiichiro Kondo, Misao Yasumuro, Seigo Nakaya, Nobuyuki Suzuki
  • Publication number: 20140356337
    Abstract: The present invention relates to a composition comprising a substrate capable of being evenly coated with a microbial biomass, wherein said biomass represents from 10% to 30% by dry matter of the total dry matter of the coated substrate. It also relates to a method for preparing said composition and to a starter fermentation activator and to a probiotic comprising said composition.
    Type: Application
    Filed: December 10, 2012
    Publication date: December 4, 2014
    Inventors: Pascal Lejeune, Jean-Bernard Souici
  • Publication number: 20140335065
    Abstract: Disclosed are nutritional compositions including human milk oligosaccharides that can be administered to individuals including preterm infants, infants, toddlers, children, and adults for preventing injury and/or improving the healing of the gastrointestinal tract. Additional suitable methods of using the nutritional compositions including the human milk oligosaccharides are also disclosed.
    Type: Application
    Filed: August 13, 2012
    Publication date: November 13, 2014
    Applicant: ABBOTT LABORATORIES
    Inventors: Steven R. Davis, Jomay Chow
  • Patent number: 8871266
    Abstract: Probiotic microorganisms are micro encapsulated by dispersing the probiotic microorganism in an aqueous suspension of a film forming protein and a carbohydrate; in an oil in water emulsion of a film forming protein and a carbohydrate and a fat; or in an oil which is subsequently dispersed in a film forming protein and a carbohydrate. The emulsion or suspension may be dried to form a powder. The probiotic may be dispersed in oil and then emulsified with the aqueous suspension and then dried to produce an encapsulated oil be dried to produce a powder. Oil suspended probiotics may be preferred where the probiotic is water sensitive. The preferred protein is casein or whey protein and the carbohydrate may be a resistant starch or a saccharide with a reducing sugar group. Where the probiotic is oxygen sensitive the protein carbohydrate is heated to create Maillard reaction products in the encapsulating film.
    Type: Grant
    Filed: March 30, 2004
    Date of Patent: October 28, 2014
    Assignee: Commonwealth Scientific & Industrial Research Organisation
    Inventors: Ross Crittenden, Luz Sanguansri, Mary Ann Augustin
  • Patent number: 8865157
    Abstract: The present invention provides novel therapeutic antimicrobial peptides that are bactericides and have an inhibitory effect on biofilms produced by biofilm-forming bacteria and especially biofilm-forming staphyloccocal bacteria. The invention includes the nucleic acids encoding the polypeptides, methods of treating bacterial infections, medical devices or implants or prosthetics impregnated with, covered or coated in the polypeptides, and means of delivery of the peptide to the oral cavity.
    Type: Grant
    Filed: December 16, 2010
    Date of Patent: October 21, 2014
    Assignee: The University of Manchester
    Inventors: Mathew Upton, Stephanie Sandiford
  • Patent number: 8865156
    Abstract: The invention provides compositions comprising one or more isolated LDH-deficient mutans streptococcus strains and one or more isolated S. oralis strains and/or one or more isolated S. uberis strains. Compositions of the invention are useful to maintain oral health, by for example treating and/or preventing one or more symptoms of dental caries, periodontitis and/or other oral cavity diseases or wounds.
    Type: Grant
    Filed: January 31, 2011
    Date of Patent: October 21, 2014
    Assignee: Oragenics, Inc.
    Inventor: Jeffrey D. Hillman
  • Publication number: 20140301994
    Abstract: The invention relates to an anhydrous mixture of biologically active probiotic bacteria for topical administration and methods of making thereof. The mixture of the invention is used for hydrating the skin, reducing and preventing fine lines and wrinkles, treating acne and decreasing skin inflammation.
    Type: Application
    Filed: November 1, 2012
    Publication date: October 9, 2014
    Inventors: Andrew M. Klapper, Spencer J. Malkin
  • Publication number: 20140294789
    Abstract: Disclosed are nutritional compositions including galactooligosaccharides that can be administered to individuals including preterm infants, infants, toddlers, children, and adults for preventing injury and/or improving the healing of the gastrointestinal tract. Additional suitable methods of using the nutritional compositions including the galactooligosaccharides are also disclosed.
    Type: Application
    Filed: July 19, 2012
    Publication date: October 2, 2014
    Applicant: ABBOTT LABORATORIES
    Inventors: Steven R. David, Jomay Chow
  • Publication number: 20140294787
    Abstract: Nutritional products having improved cohesiveness of food boluses and methods of making and using same are provided. The nutritional products may include nutritional compositions and high molecular weight, water-soluble polymers such that the nutritional products have extensional viscosities that provide improved cohesiveness to the nutritional products and Trouton ratios of at least 6. Methods of administering such nutritional products to patients having impaired swallowing ability and/or dysphagia are also provided.
    Type: Application
    Filed: March 1, 2012
    Publication date: October 2, 2014
    Inventors: Adam Stewart Burbidge, Jan Engmann, Simina Popa Nita
  • Publication number: 20140294788
    Abstract: The present disclosure provides methods for enhancing muscle protein synthesis following physical exertion. In a general embodiment, a method for enhancing muscle protein synthesis following physical exertion is provided and includes administering to an individual a composition comprising from about 15 to about 35 g protein immediately following concurrent training. Programs for enhancing muscle adaptation resulting from concurrent training are also provided. The programs include providing a composition comprising from about 15 to about 35 g protein; and providing guidelines for consumption including a recommendation of the amount of the composition to consume immediately following concurrent training.
    Type: Application
    Filed: March 20, 2014
    Publication date: October 2, 2014
    Applicant: Nestec S.A.
    Inventors: David Mark BAILEY, Eric Scott ZALTAS, Daniel Ryan MOORE, Trent STELLINGWERFF
  • Publication number: 20140271585
    Abstract: Use of a probiotic for the treatment of chronic idiopathic emesis in canines and felines.
    Type: Application
    Filed: March 12, 2014
    Publication date: September 18, 2014
    Applicant: The lams Company
    Inventor: Jean Soon Park
  • Publication number: 20140248246
    Abstract: The present invention relates to edible webs comprising microorganisms, such as probiotics. In particular, the present invention relates to an edible web having microorganisms, such as bacteria, probiotic bacteria, bacteriophages or viruses printed thereon, e.g. by the use of inkjet printing. In addition the invention relates to methods of producing such edible webs, to various products comprising the edible webs as well as to use of the edible webs comprising microorganisms.
    Type: Application
    Filed: October 5, 2012
    Publication date: September 4, 2014
    Inventor: Martinas Kuslys
  • Publication number: 20140234279
    Abstract: A feed additive composition comprising a direct fed microbial in combination with a protease, a xylanase, an amylase and a phytase, and a method for improving the performance of a subject or for improving digestibility of a raw material in a feed (e.g. nutrient digestibility, such as amino acid digestibility), or for improving nitrogen retention, or for avoiding the negative effects of necrotic enteritis or for improving feed conversion ratio (FCR) or for improving weight gain in a subject or for improving feed efficiency in a subject or for modulating (e.g. improving) the immune response of the subject or for promoting the growth of beneficial bacteria in the gastrointestinal tract of a subject, which method comprising administering to a subject a direct fed microbial in combination with a protease, a xylanase, an amylase and a phytase.
    Type: Application
    Filed: January 19, 2012
    Publication date: August 21, 2014
    Applicant: DUPONT NUTRITION BIOSCIENCES APS
    Inventor: Luis Fernando Romero Millan
  • Publication number: 20140193464
    Abstract: A dry, stable and viable probiotic composition comprising, a probiotic microorganism and a dried plant powder, with the proviso that said composition is not a blended mixture of at least one biologically pure Pediococcus acidilactici probiotic culture and dried tomato powder at a weight ratio of 1:4 encapsulated in an effective amount in a gelatin capsule.
    Type: Application
    Filed: January 8, 2013
    Publication date: July 10, 2014
    Applicant: IMAGILIN TECHNOLOGY, LLC
    Inventor: Jhy-Jhu Lin
  • Publication number: 20140193367
    Abstract: The invention relates to a probiotic composition for reducing uremic toxins and the manufacturing method thereof. The probiotic composition comprises at least one selected from the group consisting of: Lactobacillus plantarum BCRC 12251, Lactobacillus paracasei BCRC 12188, Streptococcus thermophilus BCRC 13869 and pharmaceutically acceptable vehicles, excipients, diluents, adjuvants, etc. The invention further relates to a probiotic composition consisted of Lactobacillus plantarum BCRC 12251, Lactobacillus paracasei BCRC 12188, Streptococcus thermophilus BCRC 13869 and pharmaceutically acceptable vehicles, excipients, diluents, adjuvants, etc. In addition, the invention relates to a novel use of the probiotic composition for reducing uremic toxins, wherein the uremic toxins are protein-bound uremic toxins.
    Type: Application
    Filed: March 15, 2013
    Publication date: July 10, 2014
    Applicants: NATIONAL TAIWAN UNIVERSITY, CONMED PHARMACEUTICAL & BIO-MEDICAL CORPORATION
    Inventors: Chen-Yu Fang, Bao-Ji Chen, Ming-Ju Chen, Je-Ruei Liu
  • Patent number: 8771673
    Abstract: A method of combating rheumatoid arthritis, comprising administering to a human subject in need thereof, an effective oral dose of a probiotic composition in an oral dose form including, as the only bacterial species therein, the bacterial species of Bacillus subtilis, Bacillus coagulans, and Enterococcus faecium. The initial occurrence, and progress of remission of the rheumatoid arthritis condition incident to such probiotic therapy, may be established and monitored by assay of rheumatoid factor and/or anti-CCP antibodies present in a blood sample of the human subject.
    Type: Grant
    Filed: June 5, 2012
    Date of Patent: July 8, 2014
    Assignee: Cobb & Associates
    Inventors: Mark L. Cobb, Alyson J. Cobb
  • Patent number: 8758013
    Abstract: Prosthetic apparatuses with probiotic microorganisms to control colonization of pathogenic bacteria are disclosed. The prosthetic apparatus may include a first portion having a first mating surface, a second portion having a second mating surface that conforms to the first mating surface, and at least one strain of probiotic microorganisms retained between the first and second mating surfaces prior to implantation of the prosthetic apparatus.
    Type: Grant
    Filed: February 24, 2012
    Date of Patent: June 24, 2014
    Assignee: Zimmer Dental, Inc.
    Inventor: John Zacharia
  • Patent number: 8753624
    Abstract: An isolated Lactobacillus paracasei strain GMNL-133 is disclosed, which was deposited in the China Center for Type Culture Collection (CCTCC) under the accession number of CCTCC M 2011331 is disclosed. The isolated Lactobacillus paracasei strain GMNL-133 is used for preparing a composition for use in the treatment of atopic dermatitis or other allergic diseases in an effective amount. And a composition for use in the treatment of atopic dermatitis or other allergic diseases comprises an effective amount of the Lactobacillus paracasei strain GMNL-133 is also disclosed.
    Type: Grant
    Filed: October 14, 2011
    Date of Patent: June 17, 2014
    Assignee: GenMont Biotech Incorporation
    Inventors: Ying-Chen Lu, Feng-Ching Hsieh
  • Publication number: 20140161781
    Abstract: The invention relates to a zinc-enriched biomass comprising living or subsequently killed micro-organisms, selected from the group consisting of Streptococcus thermophilus and Bifidobacterium animalis subsp. lactis and combinations thereof, a method for the manufacture of said zinc-enriched biomass, as well as food preparations, nutraceutic products, functional foods, cosmetic and cosmeceutic products, and food supplements, comprising the said biomass. Furthermore, new micro-organism strains are described which are able to concentrate zinc within the cell in very high amounts and therefore are particularly suitable for use in the method of the invention.
    Type: Application
    Filed: November 4, 2013
    Publication date: June 12, 2014
    Inventors: Alberto BENEDETTI, Francesco GIRARDO
  • Publication number: 20140161780
    Abstract: A protein-rich nutritional food product composed of a probiotic and an edible isolated protein. The probiotic component may comprise Lactobacillus, Bacillus, Streptococcus Bifidobacteria, Saccharomyces or Leuconostoc. The isolated protein may comprise whey proteins, whey growth factor extract, glutamine peptide, egg albumen, soy proteins, or caseinates. This nutritional composition can be in the form of a food product, dietary supplement, or medical food which, upon ingestion, will promote a healthy intestinal microenvironment, provide a source of protein, and assist in the elimination of nitrogenous waste products that can build up in concentration in the circulating blood. Increased concentrations of the wastes are known to exert a negative impact on an individual's physiology and contribute to a decreased sense of well-being and general malaise. Methods for removing nitrogenous waste products from the blood and ameliorating renal failure using the nutritional product of the invention are also provided.
    Type: Application
    Filed: September 12, 2011
    Publication date: June 12, 2014
    Applicant: Kibow Biotech ,Inc.
    Inventor: Natarajan Ranganathan
  • Publication number: 20140147426
    Abstract: The present invention discloses different specific bacterial strains isolated from individuals without caries which are characterised in that they present inhibitory activity against cariogenic organisms. The invention also discloses a process for isolating said strains, as well as bioactive peptides, such as anti-microbial peptides of human and bacterial origin, which also show anti-cariogenic activity. Moreover, the present invention also discloses pharmaceutical and/or probiotic/prebiotic compositions, functional foods, mouthwashes, toothpaste, chewing gum, etc., that comprise at least one of the strains and/or at least one of the bioactive peptides described in the invention, or a combination thereof, which are useful in the treatment and/or prevention of infectious diseases of the buccal cavity, preferably caries.
    Type: Application
    Filed: August 31, 2011
    Publication date: May 29, 2014
    Applicant: CENTRO SUPERIOR DE INVESTIGACION EN SALUD PUBLICA (CSISP)
    Inventor: Alejandro Mira Obrador
  • Patent number: 8734784
    Abstract: The invention relates to a composition comprising a combination of an elder extract (Sambucus nigra) and a strain of L. paracasei, L. casei, L. bulgaricus or S. thermophilus, intended for stimulating immunity and/or promoting an anti-infectious and/or anti-inflammatory response.
    Type: Grant
    Filed: October 16, 2009
    Date of Patent: May 27, 2014
    Assignees: Pierre Fabre Medicament, Compagnie Gervais Danone
    Inventors: Anne Mandeau, Christine Libon, Marie-Françoise Aries, Gianfranco Grompone, Violeta Niborski
  • Publication number: 20140140970
    Abstract: An individual at risk for necrotizing enterocolitis and related disorders can be identified by measuring the level of at least one secretor antigen in a biological sample from the individual and comparing the measured level of the at least one secretor antigen to a predetermined value or a predetermined range of values. Among the secretor antigens which can be measured are: the H-1, H-2, Lewisb and Lewisy antigens and derivatives thereof (e.g., a sialylated form of Lewis a, Lewis x, Lewis b, Lewis y; H-1, H-2, Lewis a, Lewis x, Lewis b or Lewis y).
    Type: Application
    Filed: October 2, 2013
    Publication date: May 22, 2014
    Applicants: Children's Hospital Medical Center, Instituto Nacional de Ciencias Medicas Y Nutricion, The General Hospital Corporation
    Inventors: Ardythe L. Morrow, David S. Newburg, Guillermo M. Ruiz-Palacios
  • Publication number: 20140140971
    Abstract: The invention relates to a composition which, depending on the user, may be taken as a nutritional, dietetic or strictly therapeutic preparation, comprising as its active substance alkaline sphingomyelinase which is capable of preventing or treating various pathological conditions including cancerous processes, inflammatory processes of the intestine, hypercholesterolaemia and infections with Helicobacter pylori.
    Type: Application
    Filed: January 27, 2014
    Publication date: May 22, 2014
    Applicant: VSL PHARMACEUTICALS INC.
    Inventor: Claudio DE SIMONE
  • Patent number: 8728490
    Abstract: Described are Streptococcus suis infections in pigs, vaccines directed against those infections and tests for diagnosing S. suis infections. Provided is an isolated or recombinant nucleic acid encoding a capsular gene cluster of S. suis or a gene or gene fragment derived therefrom. Further provided is a nucleic acid probe or primer allowing species or serotype-specific detection of S. suis. Also provided is a Streptococcus suis antigen and vaccine derived therefrom.
    Type: Grant
    Filed: June 16, 2010
    Date of Patent: May 20, 2014
    Assignee: Stichting Dienst Landbouwkundig Onderzoek
    Inventor: Hilda Elizabeth Smith
  • Patent number: 8728461
    Abstract: A novel lactic acid bacterium strain is found, which has a high IgA production-inducing ability and a high immunostimulating activity, and belongs to the genus Enterococcus. Thus, provided is an excellent lactic acid bacterium preparation for foods or feeds, which has a high enteric colonization rate. Specifically disclosed are: a novel lactic acid bacterium Enterococcus faecium NHRD IHARA (FERM BP-11090) which has a high IgA production-inducing ability and a high immunostimulating activity; and a lactic acid bacterium preparation for enhancing the production of immunoglobulin A, which comprises a culture of the bacterium strain, an extract of the bacterium strain, or a product of any treatment of cells of the bacterium strain.
    Type: Grant
    Filed: March 30, 2009
    Date of Patent: May 20, 2014
    Assignee: Nippon Meat Packers, Inc.
    Inventors: Yasuhiro Ihara, Hiroshi Murakami, Yoichi Takahagi
  • Publication number: 20140127176
    Abstract: The present invention relates to compositions and methods for preventing and treating periodontitis and other conditions. In particular, the present invention relates to oral bacteria for use in treating and preventing diseases and conditions.
    Type: Application
    Filed: March 2, 2012
    Publication date: May 8, 2014
    Applicants: TUFTS MEDICAL CENTER, TUFTS UNIVERSITY
    Inventors: Linden Hu, Brian A. Klein, Elizabeth Tenorio
  • Patent number: RE45170
    Abstract: The invention relates to Streptococcus suis infection in pigs, vaccines directed against those infections and tests for diagnosing Streptococcus suis infections. The invention provides an isolated or recombinant nucleic acid encoding a capsular gene cluster of Streptococcus suis or a gene or gene fragment derivated thereof. The invention further provides a nucleic acid probe or primer allowing species or serotype-specific detection of Streptococcus suis. The invention also provides a Streptococcus suis antigen and vaccine derived thereof.
    Type: Grant
    Filed: August 30, 2013
    Date of Patent: September 30, 2014
    Assignee: Stichting Dienst Landbouwkundig Onderzoek
    Inventor: Hilda Elizabeth Smith