Lactobacillus Or Pediococcus Or Leuconostoc Patents (Class 424/93.45)
  • Patent number: 11185563
    Abstract: The present invention discloses uses of treating, preventing or improving bone diseases by Lactobacillus or a composition including the Lactobacillus. The Lactobacillus and compositions can increase the blood calcium concentration, the trabecular bone volume density, the trabecular thickness, the trabecular number and the bone mineral density of a subject, and reduce trabecular spacing of the subject. Further, the present invention discloses a method for treating a subject diagnosed with a bone disease, through identifying the subject having the bone disease and administering to the subject an effective amount of a composition including at least one of Lactobacillus plantarum GKM3 and Lactobacillus paracasei GKS6, wherein the Lactobacillus plantarum GKM3 is deposited in China General Microbiological Culture Collection Center (CGMCC) with a deposition number of CGMCC 14565 on Aug. 25, 2017, and the Lactobacillus paracasei GKS6 is deposited in CGMCC with a deposition number of CGMCC 14566 on Aug. 25, 2017.
    Type: Grant
    Filed: April 23, 2019
    Date of Patent: November 30, 2021
    Assignee: GRAPE KING BIO Ltd.
    Inventors: Chin-Chu Chen, Yen-Lien Chen, Shin-Wei Lin, Yen-Po Chen, Yang-Tzu Shih, Ching-Wen Lin
  • Patent number: 11160825
    Abstract: This document provides methods and materials for treating diabetes and/or liver steatosis. For example, methods for using compositions containing a potato polysaccharide preparation to reduce one or more symptoms of diabetes or liver steatosis are provided. In some cases, a composition containing a potato polysaccharide preparation provided herein can be used to treat fatty liver disease.
    Type: Grant
    Filed: August 29, 2014
    Date of Patent: November 2, 2021
    Assignee: Research Foundation of the State University of New York
    Inventors: George B. Stefano, Richard Kream, Kirk J Mantione
  • Patent number: 11135232
    Abstract: The invention discloses a composition comprising an oligosaccharide mixture, said oligosaccharide mixture comprising from 40 to 80 wt % of fucosylated oligosaccharide(s), from 10 to 50 wt % of N-acetylated oligosaccharide(s), from 5 to 40 wt % of sialylated oligosaccharide(s) and from 0 to 20 wt % of precursor(s) of human milk oligosaccharide, for use in preventing and/or in treating necrotizing enterocolitis in infants and young children.
    Type: Grant
    Filed: November 14, 2014
    Date of Patent: October 5, 2021
    Assignee: Societe des Produits Nestle S.A.
    Inventor: Per Torp Sangild
  • Patent number: 11123385
    Abstract: Provided are a functional food or pharmaceutical composition or a method for preventing, alleviating or treating hyperphosphatemia and chronic kidney disease and treating chronic kidney disease using the composition comprising Lactobacillus sp. KCCM 11826P having excellent phosphorus-absorbing ability.
    Type: Grant
    Filed: January 26, 2017
    Date of Patent: September 21, 2021
    Assignees: Korea Food Research Institute, Catholic Kwandong University Industry Foundation
    Inventors: Hyo Jin Kim, Hae Won Jang, Young-Wook Chin, Woo Kyung Kang, Sung Jin Moon
  • Patent number: 11103157
    Abstract: Systems and methods have been developed for implementation of a portable SIBO testing system for convenient sampling of intestinal gases exhaled from a patient's breath. These devices may be in the form of a hand held meter that would integrate with a smartphone or other device with an application that can record data relating to food consumed by a user. Various technologies may be utilized to measure the levels of gases exhaled by a user, which may include (1) sorbent based technology and (2) membrane based technology. In some examples, the system will determine an indication of whether a patient has SIBO by adjusting a change in exhaled hydrogen concentration by a methane level exhaled by a patient.
    Type: Grant
    Filed: August 30, 2016
    Date of Patent: August 31, 2021
    Inventors: Kapil Gupta, Mark Pimentel, Ali Rezaie
  • Patent number: 11096410
    Abstract: The invention discloses a composition comprising oligosaccharide, for use in the prevention and/or treatment of skin conditions and/or skin diseases by increasing SCFA, in particular colonic propionate and butyrate. Said skin disease is in particular atopic dermatitis.
    Type: Grant
    Filed: January 26, 2017
    Date of Patent: August 24, 2021
    Assignee: Societe des Produits Nestle S.A.
    Inventors: Carine Blanchard, Chiara Nembrini
  • Patent number: 11096948
    Abstract: Composition and methods suitable for treating Helicobacter infection and diseases associated therewith are provided. The composition containing fusidic acid or a pharmaceutically acceptable salt or solvate thereof.
    Type: Grant
    Filed: January 16, 2017
    Date of Patent: August 24, 2021
    Assignee: DEXCEL PHARMA TECHNOLOGIES LTD.
    Inventor: Dan Oren
  • Patent number: 11090357
    Abstract: The present application relates to an animal feed supplement for improving animal health and meat production compromising Next Generation Bioengineered Probiotics (NGBP). In some embodiments, the present application relates to a method for treating or preventing an inflammatory condition of a patient comprising the step of administering a therapeutically effective amount of Generation Bioengineered Probiotics (NGBP), together with one or more pharmaceutically acceptable carriers, diluents, and excipients, to the patient in need of relief from said inflammatory condition. In some other embodiments, the present invention relates to method for improving animal health and/or meat production comprising the step of adding an effective amount of Next Generation Bioengineered Probiotics (NGBP) to the feed of said animal.
    Type: Grant
    Filed: July 1, 2019
    Date of Patent: August 17, 2021
    Assignee: Purdue Research Foundation
    Inventors: Arun K Bhunia, Rishi Drolia, Ok Kyung Koo, Mary Anne Amalaradjou
  • Patent number: 11065200
    Abstract: The present invention relates to medical devices in the form of mucoadhesive films for the release of live lactic bacteria and bifidobacteria (probiotics) and/or for the release and maintenance of their pharmacologically useful enzyme activities.
    Type: Grant
    Filed: March 14, 2018
    Date of Patent: July 20, 2021
    Assignee: MENDES S.R.L.
    Inventor: Seok-Jin Kim
  • Patent number: 11052117
    Abstract: The present invention relates to administration of sweet whey protein (SWP) for promoting the enteric neuronal development in infants, especially preterm, low birth, very low and extremely low birth weight infants as well as in young children up until the age of six. Administration of the SWP according to the invention prevents and treats disorders associated with an immature or impaired enteric nervous system. The disorders are, notably, dysfunctional gastrointestinal motility manifested as slow intestinal transit, intestinal discomfort, hard stools, constipation and/or gastrointestinal reflux, gut barrier dysfunction, food intolerance or necrotizing enterocolitis.
    Type: Grant
    Filed: December 12, 2014
    Date of Patent: July 6, 2021
    Assignee: Societe des Produits Nestle S.A.
    Inventor: Magali Faure
  • Patent number: 11053474
    Abstract: The invention concerns novel Lactobacillus strains and the uses thereof, in particular for preserving foods, animal feedstuff, pharmaceutical compositions and/or cosmetic compositions.
    Type: Grant
    Filed: March 12, 2014
    Date of Patent: July 6, 2021
    Assignee: Novozymes A/S
    Inventors: Detlef Goelling, Andreas Heilmann, Christine Lang
  • Patent number: 11044935
    Abstract: The invention relates to process for converting berry and/or fruit materials to fractions comprising bioactive compounds, said process comprising the steps, where at least one berry material or fruit material selected from berries, fruits, by-products, side streams and waste materials originating from berries or fruits, and any combinations thereof is sieved whereby a seed fraction is separated from a skin fraction, the seed fraction is subjected to sanding and a seed coat fraction comprising surface layer of the seeds and a sanded seed fraction comprising the sanded seeds are obtained.
    Type: Grant
    Filed: December 17, 2015
    Date of Patent: June 29, 2021
    Assignee: TEKNOLOGIAN TUTKIMUSKESKUS VTT OY
    Inventors: Riitta Puupponen-Pimiä, Liisa Nohynek, Tuija Kössö, Mirja Mokkila
  • Patent number: 11019838
    Abstract: Dietary supplements comprising one or more probiotic bacteria or probiotic yeast in an oil with calcium phosphate added are provided. The calcium phosphate substantially reduces clumping and/or settling of the probiotic in oil. Other additives, such as anti-oxidants and taste enhancers, may be added to the compositions.
    Type: Grant
    Filed: February 21, 2018
    Date of Patent: June 1, 2021
    Assignee: Jarrow Formulas, Inc.
    Inventors: Jarrow Rogovin, Peilin Guo
  • Patent number: 11007235
    Abstract: The inventions disclosed herein relate to the findings that L. reuteri bacteria isolated from dog saliva is capable of modulating a subject's body weight. In certain aspects, the inventions disclosed herein relate to the findings that L. reuteri species isolated from dog saliva elevates a subject's oxytocin levels in blood plasma and surprisingly, the killed (lysed) bacteria was sufficient to achieve the observed effects.
    Type: Grant
    Filed: June 22, 2017
    Date of Patent: May 18, 2021
    Inventor: Susan E. Erdman
  • Patent number: 11007234
    Abstract: A composition including one or more bacteria of the order Anaeroplasmatales for use as a medicament in methods of treatment or prevention of an inflammatory disorder of the digestive system. Preferred embodiments of the invention relate to methods employing Anaeroplasma in the treatment or prevention of an inflammatory disorder of the digestive system. Preferably, the inflammatory disorders of the digestive system are inflammatory bowel disease, colitis, Crohn's disease (CD) or ulcerative colitis (UC). Furthermore, it is preferable that the composition of the present invention causes increased TGF-? and/or IgA production in the intestine or other component of the digestive tract compared to subjects who have not received administration of the composition.
    Type: Grant
    Filed: September 7, 2018
    Date of Patent: May 18, 2021
    Assignee: DEUTSCHES RHEUMA-FORSCHUNGSZENTRUM BERLIN
    Inventors: Hyun-Dong Chang, Alexander Beller, Andreas Radbruch
  • Patent number: 10946050
    Abstract: The present invention provides compositions comprising a probiotc in admixture with an effective amount of an amphipathic substance that enhances viability of the probiotic in the composition when the composition is subjected to heat.
    Type: Grant
    Filed: November 30, 2016
    Date of Patent: March 16, 2021
    Assignee: IMAGILIN TECHNOLOGY LLC
    Inventors: Jhy-Jhu Lin, Jolinta Lin
  • Patent number: 10925908
    Abstract: The subject invention provides materials and methods that effectively support innate immunity and/or disperse pathogenic biofilms using readily available, nontoxic, natural substances, while supporting restoration of normal microbiotic homeostasis. In one embodiment, the subject invention provides anti-biofilm compositions comprising one or more probiotic organisms, anti-microbial honey, and other ingredients such as prebiotic compounds, other hive products, green tea derivatives, other plant derivatives, and vitamin D3.
    Type: Grant
    Filed: August 20, 2018
    Date of Patent: February 23, 2021
    Assignee: QUORUM INNOVATIONS, LLC
    Inventors: Eva A. Berkes, Nicholas T. Monsul, Frederick T. Boehm
  • Patent number: 10925907
    Abstract: Isolated Lactobacillus strains are useful in preventing or delaying the development of Type 1 Diabetes (T1D). A probiotic composition comprising the Lactobacillus strains and use of the composition in T1D prevention are provided.
    Type: Grant
    Filed: June 4, 2018
    Date of Patent: February 23, 2021
    Assignee: Universtiy of Florida Research Foundation, Incorporated
    Inventor: Graciela Liliana Lorca
  • Patent number: 10918679
    Abstract: Disclosed are compositions and methods for reducing blood alcohol content following alcohol consumption. The inventive compositions and methods rapidly reduce blood alcohol content and alleviate symptoms of intoxication in a subject having an elevated blood alcohol content due to alcohol consumption.
    Type: Grant
    Filed: February 28, 2017
    Date of Patent: February 16, 2021
    Assignee: LIFE WELL LIVED, LLC
    Inventors: Roxanne Smith, Jonathan Rinker, Kent Howard
  • Patent number: 10918653
    Abstract: Oligosaccharides from bovine milk, whey and dairy products, and methods of producing bovine milk oligosaccharides are provided.
    Type: Grant
    Filed: October 29, 2019
    Date of Patent: February 16, 2021
    Assignee: THE REGENTS OF THE UNIVERSITY OF CALIFORNIA
    Inventors: J. Bruce German, David Mills, Carlito B. Lebrilla, Daniela Barile, Riccardo LoCascio
  • Patent number: 10898529
    Abstract: A method is provided of selecting specific probiotic lactic acid bacteria producing histamine and the use of such strains for beneficial effects for mammals. The method includes selecting a lactic acid bacterial strain for use in the local production of histamine in a mammal, and further comprises screening bacteria for the presence of an active histidine operon and selecting a strain which has an active histidine operon and is capable of producing histamine. Preferably said strain is selected for its ability to produce histamine at a level of greater than 250 pg/ml. The present invention further provides products comprising the strains obtainable by the selection methods of the invention for use in the local production of histamine in a mammal, in particular for use in the treatment or prophylaxis of inflammatory conditions.
    Type: Grant
    Filed: May 23, 2018
    Date of Patent: January 26, 2021
    Assignee: BIOGAIA AB
    Inventors: James Versalovic, Carissa Michelle Thomas, Eamonn Connolly
  • Patent number: 10898521
    Abstract: Here disclosed is a method of preparing an antimicrobial strain composition from milk, a raw egg and a plant part, which includes the following steps: 1) providing a dairy composition comprising milk, a fermentable sugar, and edible starters from each of Lactobacillus, Bifidobacterium and Acetobacter, combining a first aliquot of the dairy composition (part A) with Rhizopus oryzae, Aspergillus niger and/or Aspergillus oryzae, and an edible starter from Saccharomyces, and conducting fermentation so as to enable the part A composition to substantially turn into a milk curd, 3) combining a second aliquot of the dairy composition (part B) with a raw egg, conducting fermentation so that eggshell substantially dissolves into the part B composition, making an opening on an eggshell membrane(s) without substantially affecting the construction of the eggshell membrane(s), and continuing fermentation of the part B composition until appearance of calcium particles on an inner surface of the eggshell membrane(s), 4) comb
    Type: Grant
    Filed: January 1, 2020
    Date of Patent: January 26, 2021
    Inventors: Amy Li, Jielong Liu, Xia Liu, Li Wang
  • Patent number: 10864236
    Abstract: The invention provides compositions comprising bacterial strains for treating and preventing inflammatory and autoimmune diseases.
    Type: Grant
    Filed: January 16, 2019
    Date of Patent: December 15, 2020
    Assignee: 4D Pharma Research Limited
    Inventors: George Grant, Angela Margaret Patterson, Imke Mulder, Seanin McCluskey, Emma Raftis
  • Patent number: 10842832
    Abstract: The invention features the use of a defined microbial consortia for the replacement of a gut microbiome associated with disease. In particular, the invention provides for the treatment of hyperammonemia, Clostridium difficile colitis, hepatic encephalopathy associated with cirrhosis, and inflammatory bowel disease.
    Type: Grant
    Filed: August 28, 2018
    Date of Patent: November 24, 2020
    Assignee: The Trustees of The University Of Pennsylvania
    Inventors: Frederic Bushman, Gary Wu, James Lewis, Mark Goulian
  • Patent number: 10842831
    Abstract: The present disclosure provides methods, systems, compositions, and kits to address the need for microbiome-related treatment of health conditions and disease. The present disclosure provides for treatment of metabolic conditions using microbial compositions.
    Type: Grant
    Filed: October 12, 2018
    Date of Patent: November 24, 2020
    Assignee: Pendulum Therapeutics, Inc.
    Inventors: Colleen Cutcliffe, John S. Eid, James H. Bullard, Marcus F. Schicklberger
  • Patent number: 10780137
    Abstract: The present invention relates to compositions comprising at least about 8% ?-glucans and/or at least about 8% ?-fucans, which has a prebiotic effect and act as a replacement for in-feed antibiotics. The present invention also relates to extraction methods to obtain such extracts and various uses for the compositions comprising ?-glucans and/or ?-fucans.
    Type: Grant
    Filed: July 8, 2019
    Date of Patent: September 22, 2020
    Assignee: Bioatlantis Limited
    Inventors: John O'Doherty, John T. O'Sullivan
  • Patent number: 10780135
    Abstract: A composition of probiotics is provided which promotes weight loss and maintenance thereof. More particularly, a probiotic mixture of Lactobacillus gasseri, Lactobacillus fermentum, and Lactobacillus rhamnosus are provided to reduce body adiposity, decrease inflammation of adipose tissue, and enhance metabolism in optional combination with prebiotics and excipients such as flow agents and binders. A method of administering the probiotic composition to an individual user is also provided.
    Type: Grant
    Filed: April 5, 2018
    Date of Patent: September 22, 2020
    Inventor: Hooman M. Melamed
  • Patent number: 10779550
    Abstract: A nutritional composition comprising at least one human milk oligosaccharide selected from 6? sialyllactose, lacto-N-neotetraose, lacto-N-tetraose, disialylated lacto-N-tetraose, 3?-fucosyllactose, and 3?-sialyllactose. The nutritional composition is used in a method of reducing stress in an individual in need thereof.
    Type: Grant
    Filed: December 18, 2013
    Date of Patent: September 22, 2020
    Assignee: ABBOTT LABORATORIES
    Inventors: Jomay Chow, Matthew Panasevich
  • Patent number: 10758555
    Abstract: The present invention relates to a composition comprising at least one fucosylated oligosaccharide, for use in preventing allergies and/or treating allergies and/or reducing the occurrence or the risk of allergies in an infant or a young child born from a mother deficient in at least one fucosylated oligosaccharide(s) or fed with a mother's milk deficient in at least one fucosylated oligosaccharide(s). The use of said composition in infant formula, milk fortifier or children's food is foreseen.
    Type: Grant
    Filed: November 4, 2014
    Date of Patent: September 1, 2020
    Assignee: Societe des Produits Nestle S.A.
    Inventors: Dominique Brassart, Clemens Kunz, Norbert Sprenger
  • Patent number: 10729804
    Abstract: The present invention relates to the use of nanofibrillar cellulose hydrogel in cell culture and medical applications. The invention relates to a composition comprising nanofibrillar cellulose, cross linkable polymer and at least one bioactive agent. The invention also provides methods for producing the composition and uses thereof. The present invention further relates to the use of said composition for manufacturing of a shaped matrix, the method of preparing said matrix, the matrix and the use of said matrix in various applications.
    Type: Grant
    Filed: February 10, 2016
    Date of Patent: August 4, 2020
    Assignee: UPM-KYMMENE CORPORATION
    Inventors: Marjo Yliperttula, Patrick Lauren, Petter Somersalo, Yanru Lou
  • Patent number: 10716817
    Abstract: Molecules secreted or derived from probiotic bacteria are provided for use in compositions and methods for the treatment and/or prevention of infection by pathogenic viruses. The isolated secreted molecules can also be used in nutritional or medical food products which provide probiotics to the gastrointestinal tract of a mammal.
    Type: Grant
    Filed: December 8, 2017
    Date of Patent: July 21, 2020
    Assignee: UNIVERSITY OF GUELPH
    Inventor: Mansel Griffiths
  • Patent number: 10675311
    Abstract: This invention provides lactic acid bacteria that have one or more effects selected from among fatigue-ameliorating effect, blood circulation-improving effect, stool odor-reducing effect, and growth-promoting effect and that can be used with high safety. This invention further provides a pharmaceutical preparation comprising, as an active ingredient, lactic acid bacteria that have one or more effects selected from among fatigue-ameliorating effect, blood circulation-improving effect, stool odor-reducing effect, and growth-promoting effect. According to the invention, novel lactic acid bacteria belonging to the Enterococcus faecium species having particular mycological properties and exhibiting viability of 40% or higher when freeze-dried in the absence of a dispersion medium and viability of 80% or higher in a probiotic preparation when stored at 40° C.
    Type: Grant
    Filed: July 7, 2016
    Date of Patent: June 9, 2020
    Assignee: KANEKA CORPORATION
    Inventors: Airo Tategaki, Taizo Kawabe, Hozumi Tanaka
  • Patent number: 10668118
    Abstract: Provided herein are, inter alia, microbial compositions and methods of using the same. The microbial compositions provided include, inter alia, therapeutically effective amounts of Lactobacillus johnsonii, Faecalibacterium prausnitzii, Akkermansia muciniphila, Myxococcus xanthus and Pediococcus pentosaceus and are particularly useful for methods of treating and preventing inflammatory diseases.
    Type: Grant
    Filed: April 5, 2018
    Date of Patent: June 2, 2020
    Assignee: The Regents of the University of California
    Inventors: Susan Lynch, Nikole Kimes, Din Lin, Ricardo Valladares, Kei Fujimura
  • Patent number: 10660857
    Abstract: The disclosure provides an oral composition for reducing serum cholesterol, serum lipids, body fat, or atherogenic index or for prophylaxis or treatment of atherosclerosis, cardiovascular or cerebrovascular diseases, comprising a highly bsh active bacteria, isolate or supernatant thereof; wherein the highly bsh active bacteria degrades >50 ?mol glycodeoxycholic acid (GDCA)/gram/hour and >2 ?mol taurodeoxycholic acid (TDCA)/gram/hour when measured over 1 hour and 5 hours, respectively, or degrades >65 ?mol GDCA/g/hr and >7 ?mol TDCA/g/hr when measured over 30 minutes.
    Type: Grant
    Filed: May 19, 2011
    Date of Patent: May 26, 2020
    Assignee: UAS Laboratories LLC
    Inventors: Satya Prakash, Mitchell Lawrence Jones, Christopher Martoni
  • Patent number: 10646522
    Abstract: The present invention is related to a Lactobacillus strain, composition and use thereof for treating autoimmune disease and related complications. The composition comprises at least one isolate of Lactobacillus paracasei strain GMNL-32, L. reuteri strain GMNL-89 or L. reuteri strain GMNL-263, and a pharmaceutical carrier, for treating syndromes and related complications of the autoimmune diseases.
    Type: Grant
    Filed: April 16, 2018
    Date of Patent: May 12, 2020
    Assignee: GenMont Biotech Incorporation
    Inventors: Chih-Yang Huang, Wei-Wen Kuo, Bor-Show Tzang, Yi-Hsing Chen
  • Patent number: 10632156
    Abstract: The invention relates to methods of differentiation, isolation, propagation, and storage of small colony variants (SCVs) of E. coli, preferably E. coli 83972 or E. coli HU2117, or modified or variant forms thereof, and methods for using the prepared SCV bacteria to establish probiotic biofilms in treated subjects and/or on treated medical devices.
    Type: Grant
    Filed: March 27, 2015
    Date of Patent: April 28, 2020
    Assignee: Atterx Biotherapeutics, Inc.
    Inventors: Steven R. Watt, Caleb W. Dorsey, Joshua A. Smith
  • Patent number: 10596208
    Abstract: The present invention provides a pharmaceutical composition and a food composition for preventing or treating lipid-related metabolic disease, which contain, as active ingredients, probiotics and a vitamin B complex. When the composition comprising the probiotics and the vitamin B complex is used, it may further promote in vivo absorption of the vitamin B complex, and may induce a synergistic effect on a reduction in blood lipid levels, thereby exhibiting an effect on the alleviation, prevention or treatment of obesity and lipid-related metabolic disease.
    Type: Grant
    Filed: November 2, 2017
    Date of Patent: March 24, 2020
    Assignee: Cell Biotech Co., Ltd.
    Inventor: Myung Jun Chung
  • Patent number: 10597427
    Abstract: The present invention provides a diabetes-inducing bacterium and use thereof, and a reagent and a detection method for detecting the bacterium. According to the present invention, enteric colonization of the diabetes-inducing bacterium can be prevented, and diabetes can be treated and/or prevented.
    Type: Grant
    Filed: September 26, 2014
    Date of Patent: March 24, 2020
    Assignee: AJINOMOTO CO., INC.
    Inventors: Keishi Kameyama, Kikuji Itoh
  • Patent number: 10548928
    Abstract: The present invention provides the use of Lactobacillus paracasei, for maintaining or increasing the intestinal microbiota diversity in a subject having dysbiosis.
    Type: Grant
    Filed: April 15, 2015
    Date of Patent: February 4, 2020
    Assignees: COMPAGNIE GERVAIS DANONE, INSTITUT NATIONAL DE LA RECHERCHE AGRNOMIQUE
    Inventors: Gianfranco Grompone, Muriel Derrien, Johan Van Hylckama Vlieg, Pascale Serror, Lionel Rigottier-Gois, Laureen Crouzet, Claire Cherbuy
  • Patent number: 10532050
    Abstract: The invention relates to a pharmaceutical composition comprising a protein phosphatase 2A (PP2A) inhibitor and monosodium glutamate.
    Type: Grant
    Filed: April 8, 2014
    Date of Patent: January 14, 2020
    Assignee: Lixte Biotechnology, Inc.
    Inventors: John S. Kovach, Mickey L. Wells
  • Patent number: 10487305
    Abstract: The present invention relates to food-grade bacteria and methods for removing toxic compounds, including lead, cadmium, mercury, arsenic and pesticides, from contaminated environments or substances.
    Type: Grant
    Filed: April 5, 2013
    Date of Patent: November 26, 2019
    Assignees: LONDON HEALTH SCIENCES CENTRE RESEARCH INC., COMPAGNIE GERVAIS DANONE
    Inventors: Jordan Bisanz, Gregor Reid, Marc Monachese, Johan Van Hylckama Vlieg, Tamara Smokvina, Jeremy Burton
  • Patent number: 10463704
    Abstract: The present invention relates to strain of Lactobacilli and compositions containing the strain for use in modifying the absorption of cholesterol in an individual or the treatment of heart disease, diabetes or obesity.
    Type: Grant
    Filed: November 5, 2014
    Date of Patent: November 5, 2019
    Assignee: OPTIBIOTIX LIMITED
    Inventor: Stephen Patrick O'Hara
  • Patent number: 10456428
    Abstract: A method and a composition having the Lactobacillus paracasei strain GMNL-653 for treating psoriasis is provided. The Lactobacillus paracasei strain GMNL-653 has anti-inflammation properties, and inhibits the secretion of cytokine IL-6 and IL-17, so that the psoriasis symptoms caused by over-inflammation are improved/relieved.
    Type: Grant
    Filed: August 14, 2017
    Date of Patent: October 29, 2019
    Assignee: GENMONT BIOTECH INC.
    Inventors: Yi-Hsing Chen, Wan-Hua Tsai, Chia-Hsuan Chou, Pei-Jane Tsai, Tsuei Yin Huang
  • Patent number: 10420807
    Abstract: The invention relates to a new strain of Lactobacillus salivarius, products containing the new strain, the use thereof in and methods for the treatment and/or prevention of inflammation and/or infection in breast or udder tissue, particularly in a mammary gland of a human female. The inflammation and/or infection is preferably mastitis.
    Type: Grant
    Filed: December 19, 2014
    Date of Patent: September 24, 2019
    Assignee: N.V. NUTRICIA
    Inventors: Rocio Martin, Jan Knol, Leonides Fernández Álvarez, Irene Espinosa Martos, Esther Antonia Jiménez Quintana, Juan Miguel Rodríguez Gómez
  • Patent number: 10350248
    Abstract: Provided are uses of Bacteroides in preparation of a medicament. The medicament is for use in treatment or prevention of obesity and obesity-related diseases. Also provided are a pharmaceutical composition, a medicament, a food product, and an animal feed that comprise Bacteroides, uses thereof in treatment or prevention of obesity and obesity-related diseases, and a method for treatment or prevention of obesity and obesity-related diseases.
    Type: Grant
    Filed: September 30, 2014
    Date of Patent: July 16, 2019
    Assignee: RUIJIN HOSPITAL AFFILIATED TO SHANGHAI JIAO TONG UNIVERSITY SCHOOL OF MEDICINE
    Inventors: Guang Ning, Jie Hong, Weiqing Wang, Ruixin Liu, Jiqiu Wang
  • Patent number: 10299490
    Abstract: The invention provides a method for producing a soy milk fermentation product, comprising an enzyme treatment step of hydrolyzing soy milk with a peptide bond hydrolase to obtain a fermentation substrate, and a fermentation step of fermenting the fermentation substrate with lactic acid bacteria belonging to Lactobacillus brevis to obtain a fermentation product.
    Type: Grant
    Filed: March 18, 2013
    Date of Patent: May 28, 2019
    Assignee: Sapporo Holdings Limited
    Inventors: Norihiko Tsuchimoto, Yasukazu Nakakita, Hiroyuki Harashima
  • Patent number: 10286026
    Abstract: The invention covers a novel treatment strategy that considerably improves conventional probiotic treatments of inflammatory bowel diseases, irritable bowel syndrome and other gastrointestinal disorders. Both probiotic microorganisms and the carrier of the probiotic microorganisms in form of a fermented cereal gruel are used as treatment effectors. Phospholipids may also be an effecter. The novel treatment strategy is capable of removing the symptoms of inflammatory bowel diseases regardless of a mild, moderate or severe stage of the disease.
    Type: Grant
    Filed: February 15, 2017
    Date of Patent: May 14, 2019
    Assignee: NORDIC REBALANCE A/S
    Inventor: Hans Israelsen
  • Patent number: 10272100
    Abstract: Disclosed is a non-reducing end unsaturated mannuronic acid oligosaccharide having a molecular weight of 100-3000 Da, which is obtained by lysing polymannuronate as a substrate with alginate lyase, and provided are: a non-reducing end unsaturated mannuronic acid oligosaccharide; and pharmaceutical compositions for alleviating, preventing, or treating obesity, diabetes, and climacteric syndrome, and probiotics for promoting intestinal beneficial bacteria, the compositions and probiotics containing, as an active ingredient, the non-reducing end unsaturated mannuronic acid oligosaccharide, so that the antiobesity and antidiabetic effects, estrogen activity, and intestinal microflora controlling effect of the non-reducing end unsaturated mannuronic acid oligosaccharides are remarkably excellent as compared with non-reducing end saturated mannuronic acid oligosaccharides.
    Type: Grant
    Filed: August 15, 2017
    Date of Patent: April 30, 2019
    Assignee: INDUSTRY FOUNDATION OF CHONNAM NATIONAL UNIVERSITY
    Inventor: Du Woon Kim
  • Patent number: 10265351
    Abstract: Provided is a bacterial composition which comprises from 104 to 1012 cfu/g of Pediococcus pentosaceus cells which have the ability to induce the production of interleukin-10 to reduce inflammation in the intestinal tract among other features and is useful in the amelioration of excessive crying in infants.
    Type: Grant
    Filed: August 7, 2014
    Date of Patent: April 23, 2019
    Assignees: AB-BIOTICS, S.A., VANPHARMA LABORATORIOS, S. A.
    Inventors: Jordi Cune Castellana, Elisabet Lazaro Mallen, Jordi Espadaler Mazo
  • Patent number: 10265350
    Abstract: The invention relates to products and compositions that may be beneficial in animal husbandry. Said products and compositions comprise microorganisms, such as bacteria, and probiotic bacteria in particular. Thus, provided herein are microbial strains, as well as selection criteria which will enable the skilled reader to find further strains useful in the present invention. The strains, as well as compositions comprising the same, may be administered to animals, farmed animals such as swine in particular. The administration may occur in the first days of life. By administration of the products or compositions of the inventions animal growth can be promoted and animal weight can be increased. Bacterial infections may also be prevented or treated by said compounds or compositions.
    Type: Grant
    Filed: September 25, 2013
    Date of Patent: April 23, 2019
    Assignees: UNIVERSIDAD DE LEON, AQUILON CYL SOCIEDAD LIMITADA
    Inventors: Pedro Miguel Rubio Nistal, Ana María Carvajal Urueña, Marta García Díez