Lactobacillus Or Pediococcus Or Leuconostoc Patents (Class 424/93.45)
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Publication number: 20140056863Abstract: Nutritional compositions for maximizing muscle protein synthesis while minimizing the catabolism of muscle proteins and methods of using same are provided. In this manner, the nutritional compositions may provide for retention of lean body mass, which helps to avoid loss of independence and functionality, as well as to improve quality of life especially in the elderly at risk of sarcopenia and frailty. The nutritional compositions include ?-hydroxyisocaproic acid eicosapentaenoic acid. It may include other functional ingredients such as, but not limited to whey protein including whey protein micelles, prebiotic fibers, citrulline, ?-ketoglutarate, L-carnitine, nucleotides, and amino acids. Methods of administering such nutritional products to individuals in need of same are also provided.Type: ApplicationFiled: April 18, 2012Publication date: February 27, 2014Applicant: Nestec S.A.Inventors: Norman Alan Greenberg, Denis Breuille, Zamzam kabiry (Fariba) Roughead, Doug Bolster, Jennifer Mager
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Patent number: 8658157Abstract: New strains of Lactobacillus that have been selected for their capability of improved reduction the number of Streptococcus mutans in the mouth of mammals through inhibiting activity in combination with better binding to the oral mucins and dental plaque, thereby preventing, reducing or treating dental caries, and products derived from said strains, including agents for treatment or prophylaxis of caries for administration to humans.Type: GrantFiled: November 5, 2012Date of Patent: February 25, 2014Assignee: Biogaia ABInventors: Bo Mollstam, Eamonn Connolly
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Patent number: 8658156Abstract: The use of probiotic bacteria in the manufacture of a composition for administration to a woman in at least the third trimester of pregnancy for prevention of gestational diabetes, normalizing plasma glucose concentration and/or increasing insulin sensitivity.Type: GrantFiled: July 4, 2008Date of Patent: February 25, 2014Assignee: Nestec S.A.Inventors: Seppo Salminen, Erika Isolauri, Kirsi Laitinen
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Patent number: 8652461Abstract: The invention relates to a novel strain of Lactobacillus delbrueckii having blood-cholesterol-lowering properties, and to the use thereof for the manufacture of blood-cholesterol-lowering fermented products, in particular of milk products.Type: GrantFiled: November 19, 2009Date of Patent: February 18, 2014Assignee: Campagnie Gervais DanoneInventors: Agnès Meunier, Florent Lalanne, Catherine Nicolle, Artem Khlebnikov, Christèle Gaye
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Publication number: 20140044685Abstract: Nutritional compositions for maximizing muscle protein synthesis while minimizing the catabolism of muscle proteins and methods of using same are provided. In this manner, the nutritional compositions may provide for retention of lean body mass, which helps to avoid loss of independence and functionality, as well as to improve quality of life especially in the elderly at risk of sarcopenia and frailty. The nutritional compositions include ?-hydroxyisocaproic acid and citrulline. The composition may include other functional ingredients such as, but not limited to whey protein including whey protein micelles, prebiotic fibers, ?-keto-glutarate, eicosapentaenoic acid, L-carnitine, nucleotides, and amino acids. Methods of administering such nutritional products to individuals in need of same are also provided.Type: ApplicationFiled: April 18, 2012Publication date: February 13, 2014Applicant: NESTEC S.A.Inventors: Norman Alan Greenberg, Denis Breuille, Zamzam Kabiry (Fariba) Roughead, Doug Bolster, Jennifer Mager
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Patent number: 8648036Abstract: A method for inhibiting the adhesion of at least one pathogen in the gastrointestinal tract of a human is disclosed herein. In certain embodiments, the method involves administering to the human a nutritional composition including a fat or lipid source, a protein source, a prebiotic composition that includes galactooligosaccharide and/or polydextrose and lactoferrin produced by a non-human source.Type: GrantFiled: December 29, 2010Date of Patent: February 11, 2014Assignee: Mead Johnson Nutrition CompanyInventors: Anja Wittke, Dattatreya Banavara, Cecilia Munoz
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Publication number: 20140037743Abstract: The presently claimed and disclosed inventive concept(s) contemplates a novel polymeric oral dosage form (transmucosal delivery vehicle) for delivery of pharmaceutical and nutriceutical bioactive agents to the mucosa and bloodstream of the intestine. The oral dosage form of the presently claimed and disclosed inventive concept(s) comprises a polymeric coating which encapsulates the bioactive agent and inhibits degradation and dissolution of the bioactive agent within the stomach and within the lumen of the intestine until after passing through the mucosal wall of the small and/or large intestine. The enzymatic degradation of the polymeric delivery vehicle containing the bioactive agent is substantially inhibited until after absorption of the polymeric delivery vehicle into blood vessels of the intestinal mucosa.Type: ApplicationFiled: October 11, 2013Publication date: February 6, 2014Applicant: DelivRx, Inc.Inventor: Daniel R. DeBrouse
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Publication number: 20140037605Abstract: [Objects] An object of the present invention is to provide an orally administrable agent for medical use for animals for preventing or treating coccidiosis which is highly safe with no side effects, an agent for a food or a drink for use in the preservation of health, a feed additive, and a feed comprising the same. Another object of the present invention is to provide a method for rearing animals (particularly, livestock and poultry) using the same and a method for controlling coccidiosis using the same. [Means for Resolution] By using a fermentation product of a lactic acid bacterium and/or a whey fermentation product of a propionic acid bacterium as an active ingredient, an agent for preventing or treating coccidiosis, an agent for use in the preservation of health, and a feed additive can be provided.Type: ApplicationFiled: October 10, 2013Publication date: February 6, 2014Applicants: MEIJI CO., LTD., MEIJI FEED CO., LTD.Inventors: Kenji SERA, Takanori MASHIKO, Shuji IKEGAMI, Takenori ORIHASHI, Michio KANBE
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Publication number: 20140037602Abstract: Nutritional compositions for improving, treating and/or preventing various medical conditions and methods of using same are provided. The medical conditions may include allergies, autoimmune diseases, among others. The nutritional compositions include branched chain fatty acids and may include other functional ingredients such as, but not limited to probiotics, nucleotides and amino acids. Methods of administering such nutritional products to individuals in need of same are also provided.Type: ApplicationFiled: April 12, 2012Publication date: February 6, 2014Applicant: NESTEC S.A.Inventors: Doug Bolster, Norman Alan Greenberg, Jennifer Mager, Zamzam Kabiry (Fariba) Roughead
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Publication number: 20140037604Abstract: Nutritional compositions for maximizing muscle protein synthesis while minimizing the catabolism of muscle proteins and methods of using same are provided. In this manner, the nutritional compositions may provide for retention of lean body mass, which helps to avoid loss of independence and functionality, as well as to improve quality of life especially in the elderly at risk of sarcopenia and frailty. The nutritional compositions include ?-hydroxyisocaproic acid and may include other functional ingredients such as, but not limited to whey protein including whey protein micelles, prebiotic fibers, L-carnitine, nucleotides, and amino acids. Methods of administering such nutritional products to individuals in need of same are also provided.Type: ApplicationFiled: April 18, 2012Publication date: February 6, 2014Applicant: NESTEC S.A.Inventors: Norman Alan Greenberg, Denis Breuille, Zamzam Kabiry (Fariba) Roughead, Doug Bolster, Jennifer Mager
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Publication number: 20140037601Abstract: Nutritional compositions for improving, treating and/or preventing various medical conditions and methods of using same are provided. The medical conditions may include wounds, mucositis among others. The nutritional compositions include branched chain fatty acids and may include other functional ingredients such as, but not limited to probiotics, nucleotides and amino acids. Methods of administering such nutritional products to individuals in need of same are also provided.Type: ApplicationFiled: April 12, 2012Publication date: February 6, 2014Applicant: NESTEC S.A.Inventor: Norman Alan Greenberg
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Patent number: 8642021Abstract: The present invention is about conditioning compositions for hair comprising spray dried yoghurt powder and at least one cationic conditioning agent. With the compositions of the present invention hair properties such as smoothness, elasticity, volume and body and shine is improved. According to the present invention the yoghurt powder comprising compositions can be applied to hair as a shampoo, conditioner either leave in and/or rinse off types.Type: GrantFiled: December 2, 2004Date of Patent: February 4, 2014Assignee: Kao Germany GmbHInventors: Ina Brautigam, Frank Hermes
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Patent number: 8642318Abstract: Disclosed is an anti-fatty liver agent comprising a cell and/or a culture obtained by culturing a lactic acid bacterium belonging to Lactobacillus gasseri as an active ingredient. Also disclosed is a pharmaceutical agent having an anti-fatty liver activity or an anti-fatty liver beverage/food comprising a cell and/or a culture obtained by culturing a lactic acid bacterium belonging to Lactobacillus gasseri as an active ingredient.Type: GrantFiled: July 24, 2007Date of Patent: February 4, 2014Assignee: Megmilk Snow Brand Co., Ltd.Inventors: Hiroshi Kawakami, Hiroaki Matsuyama, Masao Sato, Katsumi Imaizumi
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Patent number: 8642029Abstract: The present invention relates to methods and compositions for Lactobacillus Replacement Therapy (LRT). Methods for improved stability and recovery of dried bacterial preparations are also provided.Type: GrantFiled: March 30, 2009Date of Patent: February 4, 2014Assignee: Osel, Inc.Inventors: Jun Wang, Yang Liu, Qiang Xu
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Publication number: 20140030194Abstract: The disclosure provides oral compositions and methods of using such compositions in treating subjects infected with one or more hepatic disorders. The compositions include lysates or cell wall extracts of one or more gram positive bacteria, exhibit particular activity against hepatitis C virus (HCV), and may be useful in treating those infected with HCV as well as other hepatic diseases or disorders. Also described are methods of treating a hepatic disease or disorder by administering a therapeutically effective amount of at least one therapeutically active agent capable of upregulating or downregulating the Complement system pathway, wherein the therapeutically active agent enhances the formation of one or more convertase enzymes.Type: ApplicationFiled: January 16, 2013Publication date: January 30, 2014Applicant: Labyrinth Bio, Inc.Inventor: Elizabeth McKenna
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Publication number: 20140030241Abstract: Nutritional compositions having dietary nucleotides, ?-3 fatty acids and citrulline are provided. The nutritional compositions may be formulated to improve T cell function, increase arginine availability in vivo, regulate myeloid-derived suppressor cells (“MDSC”), and decrease the risk and/or severity of infection after surgery or trauma. Methods of making, using and administering such nutritional compositions to individuals in need of same are also provided. Methods for modulating the affects of MDSC's are also provided.Type: ApplicationFiled: March 15, 2012Publication date: January 30, 2014Applicant: NESTEC S.A.Inventor: Norman Alan Greenberg
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Patent number: 8637297Abstract: The invention relates to probiotic micro-organisms isolated from faeces of children exclusively fed with breast milk. Said microorganisms are used in the food or pharmaceutical industry, especially for use in infant formula milk, due to their probiotic properties which have beneficial effects on the health of those ingesting them. Said microorganisms consist of Lactobacillus rhamnosus HERO 22A (CNCM I-4036), Lactobacillus paracasei HERO 7 (CNCM I-4034) and Bifidobacterium breve HERO 15B (CNCM I-4035).Type: GrantFiled: March 9, 2010Date of Patent: January 28, 2014Assignee: Hero AGInventors: Jose Maria Vieites Fernandez, Sergio Munoz Quezada, Inmaculada Llamas Company, Jose Maldonado Lozano, Fernando Romero Braquehais, Antonio Francisco Suarez Garcia, Angel Gil Hernandez, Carolina Gomez Llorente, Miriam Bermudez Brito
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Patent number: 8637051Abstract: The present invention is concerned with novel compositions and vaccines useful for prophylactic an/or therapeutic treatment of mucosal infections, and in particular it is concerned with oral vaccines and with methods of enhancing mucosal resistance to infection or for treating established infections, of the respiratory tract.Type: GrantFiled: May 21, 2001Date of Patent: January 28, 2014Assignee: Hunter Immunology LimitedInventors: Robert Llewellyn Clancy, Gerald Pang, Margaret Lorraine Dunkley
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Patent number: 8637001Abstract: An anti-obesity agent containing, as an active ingredient, a microorganism which belongs to the species Lactobacillus reuteri and is capable of producing lipases having the amino acid sequences respectively depicted in SEQ ID NO: 1, 3 or 5 or amino acid sequences having deletion, substitution or addition of one or more amino acids in the amino acid sequences respectively depicted in SEQ ID NO: 1, 3 or 5. The anti-obesity agent enables a patient to take a normal meal yet preventing the absorption of a fat into the body which is the primary cause of obesity.Type: GrantFiled: June 6, 2011Date of Patent: January 28, 2014Assignee: Nestec S.A.Inventors: Hidetoshi Morita, Toshio Masaoka, Takehito Suzuki
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Patent number: 8637000Abstract: An anti-obesity agent containing, as an active ingredient, a microorganism which belongs to the species Lactobacillus reuteri and is capable of producing lipases having the amino acid sequences respectively depicted in SEQ ID NO: 1, 3 or 5 or amino acid sequences having deletion, substitution or addition of one or more amino acids in the amino acid sequences respectively depicted in SEQ ID NO: 1, 3 or 5. The anti-obesity agent enables a patient to take a normal meal yet preventing the absorption of a fat into the body which is the primary cause of obesity.Type: GrantFiled: June 1, 2011Date of Patent: January 28, 2014Assignee: Nestec S.A.Inventors: Hidetoshi Morita, Toshio Masaoka, Takehito Suzuki
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Patent number: 8637296Abstract: The present invention relates to novel strains of Lactobacillus helveticus that can produce high amounts of hypotensive peptides, in particular IPP, VPP and LPP. It also relates to a fermented milk product containing a mixture of tripeptides IPP-VPP-LPP and a strain of L. helveticus. The invention further relates to the specific peptide mixture consisting of tripeptides IPP, VPP and LPP and the use of the fermented product or mixture of peptides in food products, food supplement or pharmaceutical compositions for reducing or preventing hypertension.Type: GrantFiled: June 8, 2009Date of Patent: January 28, 2014Assignee: Nestec S.A.Inventors: Martin Grigorov, Jacques-Edouard Germond, Sylvie Tournade, Michael Affolter
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Publication number: 20140023693Abstract: A simple cellulose sulphate based microencapsulation technology has been applied to encapsulate bacterial or other microbial cells, which produce and release digestive enzymes and thereby provides an acid resistant shelter for these microbial cells. Surprisingly, the resulting spheres were found to provide sufficient protection for encapsulated cells from treatment with aqueous acidic solutions. Thereby the cellulose sulphate microencapsulated cells, such as probiotics are now enabled to survive passage, for example, through the stomach after consumption by a human or animal with a higher survival rate than those not within a microcapsule. After passing the stomach these cells are delivering products produced by them, e.g. enzymes or other nutrition factors. This technology therefore proves to be very useful in providing digestive or otherwise beneficial enzymes and/or of living microbial cells, into the lower gastrointestinal tract, where they could confer their health benefit to the host.Type: ApplicationFiled: January 25, 2012Publication date: January 23, 2014Applicant: Austrianova Singapore Pte Ltd.Inventors: Walter H. Guenzburg, Eva Maria Brandtner, Brian Salmons Salmons, John A. Dangerfield
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Publication number: 20140023625Abstract: The present invention relates to compositions of rosmarinic acid or its derivatives and to the use of a hydrolytic enzyme or of microorganism containing or producing hydrolytic enzymes in these compositions. The invention also pertains to methods for improving the biological effects of the rosemary extracts and for administering such compositions to a human or animal subject for improving the skin, coat, hair or health of the subject.Type: ApplicationFiled: September 18, 2013Publication date: January 23, 2014Applicants: L'ORÉAL, Nestec S.A.Inventors: Vanessa CRESPY, Isabelle CASTIEL, Rachid BEL-RHLID, Nicolas PAGE, Thomas RAAB
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Patent number: 8632766Abstract: A subject of the invention is a composition containing strains Lactobacillus fermentum 57A, Lactobacillus plantarum 57B and Lactobacillus gasseri 57C of special characteristics such as a feature of strong diversified affinity for the digestive tract and vaginal epithelia enabling the colonization of the vagina and anus after the crossover through intestines as well as the feature of co-aggregation enabling for synergetic activity. The subject of the invention is also the application of the composition for restoration of the natural bacterial flora of the vagina and anus.Type: GrantFiled: June 4, 2008Date of Patent: January 21, 2014Assignee: Instytut Biotechnologii Surowic I Szczepionek Biomed S.A.Inventors: Piotr B. Heczko, Magdalena Strus, Grzegorz Stefański, Katarzyna Dechnik
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Publication number: 20140017291Abstract: The invention relates to porous films comprising crosslinked electrospun hydrogel fibers. Viable microbes are encapsulated within the crosslinked electrospun hydrogel fibers. The crosslinked electrospun hydrogel fibers are water insoluble and permeable. The invention also relates to methods of making and using such porous films.Type: ApplicationFiled: December 21, 2012Publication date: January 16, 2014Inventors: Devicharan Chidambaram, Ying Liu, Miriam H. Rafailovich
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Publication number: 20140017217Abstract: An object of the present invention is to provide a QOL improving or sustaining agent, a physical health improving or sustaining agent, a vitality improving or sustaining agent, a fatigue recovery or alleviating agent, or an anti-fatigue agent. Method for Achieving the Object A QOL improving or sustaining agent, a physical health improving or sustaining agent, a vitality improving or sustaining agent, a fatigue recovery or alleviating agent, or an anti-fatigue agent containing Lactobacillus ONRICb0240 (FERM BP-10065).Type: ApplicationFiled: March 28, 2012Publication date: January 16, 2014Applicant: OTSUKA PHARMACEUTICAL CO., LTD.Inventors: Mina Tsubouchi, Takao Saito, Masamichi Toba, Noriyuki Kouda, Shoji Shinkai
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Patent number: 8628763Abstract: The present invention relates to a method for the preparation of a fermented milk product comprising Bifidobacteria in combination with lactic acid bacteria of the species Lactococcus lactis, Sterptococcus thermophilus, and/or Lactobacillus bulgaricus. The problem to be solved is to provide a method to improve growth of Bifidobacteria population in milk during the fermentation process for making fermented milk products (e.g. a yogurt) in order to obtain a high cell count of Bifidobacteria in the final product.Type: GrantFiled: August 28, 2009Date of Patent: January 14, 2014Assignee: CHR-Hansen A/SInventors: Ditte Marie Folkenberg, Cecile Seimandi
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Publication number: 20140010788Abstract: This disclosure relates to enhancing growth and/or activity of lactobacilli using a prebiotic formulation which includes iso-malto oligosaccharides and ?-galactosidase; and to enhancing growth and/or activity of bifidobacteria using a prebiotic formulation which includes iso-malto oligosaccharides and ?-glucanase. Other combinations of fibers and enzymes are described below which also stimulate growth and activity of lactobacilli or bifidobacteria. These combinations of enzymes and prebiotics can be taken separately or added to foods, including desserts.Type: ApplicationFiled: September 7, 2013Publication date: January 9, 2014Applicant: Master Supplements, Inc.Inventors: Randolph S. Porubcan, Sonja Lea Yonak
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Publication number: 20140008264Abstract: A biodegradable film (4) characterized in that it is prepared from at least one co-product derived from a soya bean-processing process aimed at obtaining soya-based final products by ultrafiltration, said co-product being selected from the group comprising the okara and the permeate. Such a film can be used as a food or pharmaceutical film, in particular for preparing a product for topical administration (1) of a pharmaceutical active ingredient, such as oestrogens.Type: ApplicationFiled: November 28, 2011Publication date: January 9, 2014Applicant: Sojasun TechnologiesInventors: Theo Efstathiou, Jean-Luc Audic, Thomas Divers
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Publication number: 20140004090Abstract: A method of enhancing the antimicrobial properties of a bacterial strain, comprising cultivation of the bacterial strain in a medium comprising water, at least one component chosen from bee pollen, pollen, and bee bread, and optionally honey and/or nectar is described. The bacterial strain has the ability to be viable for at least 8 days in a 65% by weight sugar solution, preferably at least 8 days in a 70% by weight sugar solution.Type: ApplicationFiled: January 24, 2012Publication date: January 2, 2014Applicant: CONCELLAE ABInventors: Alejandra Vasquez, Tobias Olofsson
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Patent number: 8617625Abstract: Dairy compositions are provided having a high pH, of about 4.8 to about 6.2, comprising desirable probiotic cultures as well as an anti-microbial system for inhibiting undesirable pathogenic and/or spoilage microbial growth without significantly reducing the beneficial effect of the probiotic cultures.Type: GrantFiled: December 10, 2012Date of Patent: December 31, 2013Assignee: Kraft Foods Group Brands LLCInventors: Gary Francis Smith, Alice Shen Cha, Zuoxing Zheng, Michael Gerard Roman, Benjamin Emanuel Dias
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Patent number: 8617537Abstract: Methods for the controlled activation of the reuterin-production machinery of Lactobacillus reuteri by adding glycerol and other substances during the manufacture of cell-cultures and keeping the produced reuterin in the bacterial cell during preservation and storage. In particular this invention relates to the manufacture of large amounts of L. reuteri that are loaded with reuterin, and the use of such loaded bacteria for applications such as prevention and treatment of diseases, for food applications and the like.Type: GrantFiled: June 9, 2009Date of Patent: December 31, 2013Assignee: Biogaia ABInventor: Stefan Roos
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Publication number: 20130344042Abstract: The present disclosure provides compositions and methods for dietary management of celiac disease and food allergy in a subject, such as a formula-fed infant, via enteral administration of an effective amount of at least one hydrolyzed protein and Lactobacillus rhamnosus GG (LGG). The inventive nutritional compositions may contain a hydrolyzed protein component, a lipid component, a carbohydrate component, a vitamin component, a mineral component, and a prebiotic component in addition to a probiotic component, which comprises an effective amount of LGG.Type: ApplicationFiled: June 20, 2012Publication date: December 26, 2013Inventor: Gretchen Tanbonliong
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Publication number: 20130344043Abstract: The present invention provides a method for enhancing PPAR? expression, comprising administering a subject in need thereof an effective amount of Lactobacillus gasseri PM-A0005, which was deposited under Budapest Treaty in the China Center for Type Culture Collection (CCTCC), China with Deposition No. M 207039.Type: ApplicationFiled: June 20, 2013Publication date: December 26, 2013Inventors: WEI-CHIH SU, HSIANG LING CHEN, CHUN-HSIEN HUANG, HSIAO-LI WU, PEI-YU TSAI
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Publication number: 20130344045Abstract: The present invention provides a nutritional composition that is suitable to reduce the impact of stress on intestinal symptoms and/or conditions. The composition comprises one or more selected from a probiotic microorganism,one or more inactive probiotic, and one or more culture medium of one or more probiotic; and soluble fiber, and possibly other ingredients such as a milk ingredient, a source of carbohydrates and a source of protein. Preferably, the soluble fiber is a low viscosity soluble fiber. The composition is in particular suitable to alleviate abdominal discomfort, abdominal pain, abdominal cramps, and bowel movement disturbances, such as abdominal bloating, flatulence, in particular in as far as these conditions and symptoms are associated with stress.Type: ApplicationFiled: December 28, 2011Publication date: December 26, 2013Applicant: NESTEC S.A.Inventors: Magali Faure, Gabriela Bergonzelli Degonda
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Publication number: 20130344044Abstract: The present invention relates generally to the field of nutrition, more particularly to the use of probiotics in nutrition. In particular the present invention relates to the use of a probiotic or of a mixture of probiotics in the manufacture of a nutritional composition or a medicament to act the colon in a pre- or post surgical environment.Type: ApplicationFiled: August 23, 2013Publication date: December 26, 2013Applicant: NESTEC S.A.Inventor: Eduardo Schiffrin
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Publication number: 20130336942Abstract: The use of probiotic bacteria that modulate expression of a number of satiety markers in the intestine and reduces fat deposition to promote an optimal body weight of a mammal is described. The invention further relates to a composition comprising such a probiotic strain of bacteria and/or a fraction of said strain and/or metabolite of said strain for the preparation of a composition for administration to a mammal for promoting an optimal body weight of a mammal.Type: ApplicationFiled: May 22, 2013Publication date: December 19, 2013Inventors: Thomas Dyrmann Leser, Thomas GUNNARSSON, Jens KILDSGAARD, Janni Wandahl PEDERSEN, Bénédicte FLAMBARD
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Publication number: 20130336941Abstract: The present invention relates to methods for a ong-term and sustained release of flavonoids, in particular rhamnose-containing flavonoids, and for prolonging the uptake of said flavonoids in the gastro-intestinal tract. It further relates to compositions comprising said flavonoid and ?-rhamnosidase. It also encompasses compositions comprising hesperidin and hesperetin-7-gluoside.Type: ApplicationFiled: March 15, 2013Publication date: December 19, 2013Inventors: Myriam Richelle, Gary . Williamson, Ivana Jankovic, Maarit Rein
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Publication number: 20130336944Abstract: The present invention concerns strains of Lactococcus lactis capable of inhibiting the growth of a pathogenic microorganism and/or improving the intestinal epithelial barrier integrity. These strains are suitable for use in the treatment or prevention of a digestive disorder.Type: ApplicationFiled: December 17, 2010Publication date: December 19, 2013Applicant: COMPAGNIE GERVAIS DANONEInventors: Isabelle Chambaud, Biliana Lesic
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Publication number: 20130336943Abstract: An object of the present invention is to provide an effective means and method for activating vagal afferent nerve. The present invention provides a vagus nerve activator comprising bacterial cells and/or a treated product of a lactic acid bacteria as active ingredient(s).Type: ApplicationFiled: August 26, 2013Publication date: December 19, 2013Applicant: CALPIS CO., LTD.Inventors: Daisuke SAWADA, Shigeru FUJIWARA
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Publication number: 20130337056Abstract: The invention is directed to coated solid pharmaceutical preparations having a very thin coating in the nanometer range and a method for producing such preparations. The coated solid pharmaceutical preparation can be prepared by using atomic layer deposition (ALD).Type: ApplicationFiled: March 1, 2012Publication date: December 19, 2013Applicant: MERCK PATENT GMBHInventors: Lauri Lehtonen, Heike Bley, Luc Van Der Heyden
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Publication number: 20130330307Abstract: A feed additive composition comprising a direct fed microbial in combination with a protease, and a phytase, and a method for improving the performance of a subject or for improving digestibility of a raw material in a feed (e.g. nutrient digestibility, such as amino acid digestibility), or for improving nitrogen retention, or for improving the subject's resistance to necrotic enteritis or for improving feed conversion ratio (FCR) or for improving weight gain in a subject or for improving feed efficiency in a subject or for modulating (e.g. improving) the immune response of the subject or for promoting the growth of beneficial bacteria in the gastrointestinal tract of a subject, which method comprising administering to a subject a direct fed microbial in combination with a protease and a phytase.Type: ApplicationFiled: January 19, 2012Publication date: December 12, 2013Applicant: DUPONT NUTRITION BIOSCIENCES APSInventor: Luis Fernando Romero Millan
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Publication number: 20130330308Abstract: A feed additive composition comprising a direct fed microbial (DFM) in combination with a phytase derivable from Citrobacter spp. and a method for improving the performance of a subject or for improving digestibility of a raw material in a feed (e.g. nutrient digestibility, such as amino acid digestibility), or for improving nitrogen retention, or for avoiding the negative effects of necrotic enteritis or for improving feed conversion ratio (FCR) or for improving weight gain in a subject or for improving feed efficiency in a subject or for modulating (e.g. improving) the immune response of the subject, or for promoting the growth of beneficial bacteria in the gastrointestinal tract of a subject or for reducing populations of pathogenic bacteria in the gastrointestinal tract of a subject, or for reducing nutrient excretion in manure, which method comprising administering to a subject a direct fed microbial (DFM) in combination with a phytase derivable from Citrobacter spp.Type: ApplicationFiled: January 19, 2012Publication date: December 12, 2013Applicant: DUPONT NUTRITION BIOSCIENCES APSInventors: Luis Fernando Romero Millan, Luke Bernard, Peter Plumstead
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Patent number: 8603460Abstract: The invention provides certain plasmid cured strains of lactic acid bacteria modified for their capability of better acid-tolerance, a method of modifying such strains, and products containing such strains.Type: GrantFiled: June 5, 2006Date of Patent: December 10, 2013Assignee: Brogaia ABInventor: Eamonn Connolly
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Patent number: 8604005Abstract: The invention relates to the use of probiotics in the manufacture of a composition for enhancing a metabolic profile in a subject. The probiotics are capable of preventing and treating diseases or disorders associated with an abnormal metabolic profile, especially a lipid profile by normalizing the profile. The probiotics are particularly effective in down-regulating levels of lysophosphatiydylcholines (LysoPCs) and ceramides.Type: GrantFiled: February 4, 2009Date of Patent: December 10, 2013Assignee: Valio Ltd.Inventors: Kajsa Kajander, Riitta Korpela
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Patent number: 8603461Abstract: The invention provides a probiotic composition to alleviate Salmonella infection in farm animals. The composition may comprise at least one of Lactobacillus murinus, Lactobacillus pentosus, Lactobacillus salivarius sub-species salivarius, and Pediococcus pentosaceus. The composition maybe formulated as an animal feedstuff, or as a pharmaceutical composition.Type: GrantFiled: April 6, 2006Date of Patent: December 10, 2013Assignees: TEAGASC—The Agriculture and Food Development Authority, University College CorkInventors: Catherine Stanton, Colin Hill, Ger Fitzgerald, Paul Ross
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Publication number: 20130323215Abstract: The present invention discloses a novel antitumour agent which provides an antitumour activity based on metabolites with reduced side effects. Moreover, the antitumour agent is prepared starting with a highly safe bacterium used in food production, which is a probiotic lactic acid bacterium.Type: ApplicationFiled: November 29, 2010Publication date: December 5, 2013Inventors: Hooi Ling Foo, Teck Chwen Loh, Li Oon Chuah, Noorjahan Banu Alitheen, Raha Abdul Rahim
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Publication number: 20130323216Abstract: This invention relates to a preparation comprising N-acetyl-lactosamine and/or an oligosaccharide containing N-acetyl-lactosamine and a probiotic Lactobacillus sp. The invention extends to nutritional compositions comprising said preparation and to the use of the preparation in the prevention and treatment of pathogenic infections of the gastro-intestinal and upper respiratory tracts.Type: ApplicationFiled: August 9, 2013Publication date: December 5, 2013Applicant: NESTEC S.A.Inventor: Norbert Sprenger
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Publication number: 20130315990Abstract: The invention provides formulations comprising isolated Disialyllacto-N-tetraose (DSLNT) or variants, isomers, analogs and derivatives thereof.Type: ApplicationFiled: February 3, 2012Publication date: November 28, 2013Applicant: The Regents of the University of CaliforniaInventor: Lars Bode
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Patent number: 8591880Abstract: The present invention relates to supporting weight management, weight loss and/or to the prevention and/or treatment of metabolic disorders. In particular the present invention relates to preventing and/or treating metabolic disorders by modulating, in particular reducing the amount of proteobacteria and/or deferribacteres in the gut. One embodiment of the present invention relates to the use of a primary composition comprising an agent that reduces the amount of proteobacteria, preferably gamma-proteobacteria, even more preferred enterobacteria; and/or deferribacteres in the gut for the preparation of a composition to treat or prevent metabolic disorders, to support weight loss and/or to support weight management.Type: GrantFiled: July 25, 2008Date of Patent: November 26, 2013Assignee: Nestec S.A.Inventors: Chieh Jason Chou, David Philippe, Christian Darlmont, Fabrizio Arigoni, Catherine Mace