Abstract: The invention relates to two lipopeptides a1 and a2 produced by Bacillus subtilis and their use as an anitfungal agent against Aspergillus flavus. Both peptides are cyclic, acidic and have broad range of antifungal and antimicrobial activity. Both peptides belong to the Bacillomycin D family. A method and composition for controlling aflatoxin contamination in plants susceptible to alflatoxin-producing fungi, like Aspergillus flavus or Aspergillus parasiticus is also disclosed.
Type:
Grant
Filed:
April 7, 1999
Date of Patent:
February 6, 2001
Assignees:
USDA/ARS Southern Regional Research Center, Auburn University
Inventors:
Anne-Laure Moyne, Thomas E. Cleveland, Sadik Tuzun