Abstract: A dry-coated tablet for controlled release of active substance, having an erodible core tablet (1) containing at least one active substance, and a substantially erosion-resistant shell consisting of a dry-coated layer (5), is characterized in that the dry-coated layer (5) has at least one opening (6), and one end of the core tablet (1) extends as far as the opening (6).
Abstract: A stent having a polymeric coating for controllably releasing an included active agent. The polymeric coating includes a blend of a first polymeric material, which if alone, would release the agent at a first, higher rate, and a second polymeric material, which if alone would release the agent at a second, lower rate over a longer time period. One stent coating utilizes a faster releasing hydrophilic polymeric material and a slower releasing hydrophobic material. One stent coating includes a blend of a faster releasing PLA-PEO copolymer and a slower releasing PLA-PCL copolymer. One active agent is Taxol. One use of the Taxol delivering stent is to inhibit restenosis following angioplasty.
Type:
Grant
Filed:
July 2, 1999
Date of Patent:
July 10, 2001
Assignee:
SciMed Life Systems, Inc.
Inventors:
Dachuan Yang, Joel L. Stanslaski, Lixiao Wang, Scott R. Smith
Abstract: The invention provides a process for coating a branded pharmaceutical dosage form for the purpose of covering any embossed or printed matter or any colored coating by the application of an amount of a sugar based coating which is sufficient to obscure any identifying indicia without compromising the stability or releasability of the drug that is contained in the dosage form.
Type:
Grant
Filed:
January 28, 2000
Date of Patent:
July 3, 2001
Assignee:
Boehringer Ingelheim Pharmaceuticals, Inc.
Abstract: This invention is directed to a process for the preparation of enteric coated pharmaceutical dosage forms. This invention is further directed to the aqueous enteric coating dispersions suitable for use in the process and the enteric coated pharmaceutical dosage forms prepared by the process.