After Coating Patents (Class 427/224)
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Patent number: 10752983Abstract: Provided are a system and process for remanufacturing a waste cylinder assembly of an aircraft piston engine. The spraying apparatus includes a first power mechanism, a spray gun assembly and a second power mechanism. The first power mechanism drives the cylinder assembly to move in a horizontal direction and a vertical direction. The second power mechanism drives the spray gun assembly to rotate around a center of the blind hole and ensures that prepared coatings can be evenly distributed along an inner wall of the blind hole. A nozzle end of the spray gun extends into the blind hole, and the spray gun is adjustable relative to the center of the blind hole. A spraying distance is not fixed so as to change the spraying distance. Powder can be fully melted.Type: GrantFiled: July 18, 2018Date of Patent: August 25, 2020Assignee: Army Academy of Armored ForcesInventors: Haidou Wang, Guozheng Ma, Pengfei He, Shuying Chen, Fajun Ding, Yiwen Wang, Ming Liu, Haijun Wang, Shuyu Ding
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Patent number: 10125535Abstract: The invention relates to a multiple glass pane (6) comprising two outer glass panes (4, 4?), at least one center glass pane (5), and a spacer (1), wherein the spacer (1) comprises a hollow space (2, 2?) for receiving a desiccant (3) and a receiving profile (7) for each center glass pane (5), and the hollow space (2, 2?) of the spacer (1) is filled with a desiccant (3).Type: GrantFiled: April 7, 2009Date of Patent: November 13, 2018Assignee: Lisec Austria GMBHInventor: Hans Rudolf Máder
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Patent number: 9598756Abstract: A method for producing a hot dip plated steel sheet, the method controlling a coating weight by injecting a gas toward a surface of a steel sheet from a time when the steel sheet continuously immersed into a plating bath is pulled up from the plating bath to a time when plating metal adhered onto the surface of the steel sheet is solidified, the method includes: setting an oxygen concentration of a bath surface of the plating bath to be more than or equal to 0.05 vol % and less than or equal to 21 vol % when the gas is injected toward the surface of the steel sheet; and setting an oxygen concentration in a space of an end of the steel sheet at a position where the gas collides with the steel sheet pulled up from the plating bath to be more than or equal to 0.05 vol % and less than or equal to 3 vol % when the gas is injected toward the surface of the steel sheet.Type: GrantFiled: October 1, 2009Date of Patent: March 21, 2017Assignee: NIPPON STEEL & SUMITOMO METAL CORPORATIONInventors: Tooru Oohashi, Masato Kageyama, Satoshi Uchida, Katsuhiro Hamaguchi
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Patent number: 9296621Abstract: A sol-flame method includes 1) forming a sol-gel precursor solution of a source of a dopant; 2) coating a nanostructure or a thin film with the sol-gel precursor solution; and 3) subjecting the coated nanostructure or the coated thin film to flame annealing to form a doped nanostructure or a doped thin film.Type: GrantFiled: March 28, 2014Date of Patent: March 29, 2016Assignee: The Board of Trustees of the Leland Stanford Junior UniversityInventors: Yunzhe Feng, Xiaolin Zheng, In Sun Cho
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Patent number: 9221432Abstract: A snow brush, comprising flexible sheets secured by a first edge to a handle, all edges of the flexible sheets other than the first edge providing corresponding continuous brushing edges, wherein the flexible sheets are sheets of closed cells foams, and a method for fabricating the now brush, comprising selecting flexible sheets, securing a first edge of the flexible sheets to a handle, wherein selecting flexible sheets comprises selecting a number of sheets, and a thickness, a density and a free length of each sheet.Type: GrantFiled: December 9, 2013Date of Patent: December 29, 2015Assignee: GARANT GPInventor: Carl Blouin
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Publication number: 20150024155Abstract: A method of manufacturing an article comprises providing a ring for an etch reactor. Ion assisted deposition (IAD) is then performed to deposit a protective layer on at least one surface of the ring, wherein the protective layer is a plasma resistant rare earth oxide film having a thickness of less than 300 ?m and an average surface roughness of less than 6 micro-inches.Type: ApplicationFiled: September 19, 2013Publication date: January 22, 2015Applicant: Applied Materials, Inc.Inventors: Jennifer Y. Sun, Biraja P. Kanungo, Vahid Firouzdor, Ying Zhang
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Publication number: 20140294721Abstract: A sol-flame method includes 1) forming a sol-gel precursor solution of a source of a dopant; 2) coating a nanostructure or a thin film with the sol-gel precursor solution; and 3) subjecting the coated nanostructure or the coated thin film to flame annealing to form a doped nanostructure or a doped thin film.Type: ApplicationFiled: March 28, 2014Publication date: October 2, 2014Inventors: Yunzhe Feng, Xiaolin Zheng, In Sun Cho
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Patent number: 8815340Abstract: The subject of the invention is a heat treatment process by flame treatment of at least one thin film deposited on a glass substrate (1) running in the path of at least one flame treatment device comprising at least one burner (2), said treatment being able to increase the degree of crystallization of said at least one thin film and/or to increase the size of the crystallites in said at least one thin film, said process being characterized in that the maximum transient bending “b” is less than 150 mm and respects the following condition: b?0.Type: GrantFiled: March 10, 2010Date of Patent: August 26, 2014Assignee: Saint-Gobain Glass FranceInventors: Guillaume Bignon, Nicolas Nadaud, Binh Tran, Se-Jong Kim
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Publication number: 20140017457Abstract: Provided herein are methods and materials for the production of hydrophobic coatings, which may be thermally treated to produce binary hydrophobic-hydrophilic regions.Type: ApplicationFiled: July 15, 2013Publication date: January 16, 2014Applicant: THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOISInventors: Constantine M. Megaridis, Thomas M. Schutzius, Ilker S. Bayer
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Patent number: 8455571Abstract: A flame-retardant particle includes: a particle containing a compound having a structure represented by formula (1); and a coating particle that covers at least a part of a surface of the particle: -A(—O—CO—O—Ar)m??(1) wherein A represents a substituted or unsubstituted aromatic group; Ar represents a substituted or unsubstituted phenyl group; and m represents an integer of 1 to 3.Type: GrantFiled: July 9, 2008Date of Patent: June 4, 2013Assignee: Fuji Xerox Co., Ltd.Inventors: Masato Mikami, Masayuki Okoshi, Kazuya Yamanoi
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Patent number: 8329251Abstract: A method for manufacturing a dye sensitized nanocrystal film having the steps of exposing a tin oxide layer on a surface of a substrate to a flame for a time sufficient to form a layer of mesoporous, crystalline titanium oxide on the fluorinated tin oxide layer followed by sintering the substrate at a temperature of from about 300 to about 500° C. The flame contains a fuel gas, such as ethylene and oxygen and titanium organometallic. The concentration of titanium organometallic is from about 10 to about 2000 ppm. During the flame exposure step, the substrate is rotated about a central axis at a speed of from about 100 to about 600 RPM, and the flame is kept at a constant distance from the surface of the substrate. The temperature of the substrate is maintained at a temperature of less than 200° C. via the rotation and jets of gas.Type: GrantFiled: March 2, 2009Date of Patent: December 11, 2012Assignee: University of Southern CaliforniaInventors: Hai Wang, Denis J. Phares, Erik Tolmachoff
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Publication number: 20120046157Abstract: A method for strengthening an extruded catalyst honeycomb filter body, including: contacting an extruded catalyst honeycomb filter body and a siliceous formulation including at least one siliceous source comprising a silicone emulsion, a silica sol, or a combination thereof; drying the contacted filter body; and firing the dried contacted filter body to provide the filter body. Also disclosed are zeolite-based honeycomb filter articles, including a matrix of walls of: a primary phase material homogeneously distributed throughout the walls, as defined herein.Type: ApplicationFiled: August 23, 2010Publication date: February 23, 2012Inventors: Yanxia Lu, Steven Bolaji Ogunwumi, Jianhua Weng
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Publication number: 20110311732Abstract: The subject of the invention is a heat treatment process by flame treatment of at least one thin film deposited on a glass substrate (1) running in the path of at least one flame treatment device comprising at least one burner (2), said treatment being able to increase the degree of crystallization of said at least one thin film and/or to increase the size of the crystallites in said at least one thin film, said process being characterized in that the maximum transient bending “b” is less than 150 mm and respects the following condition: b?0.Type: ApplicationFiled: March 10, 2010Publication date: December 22, 2011Applicant: SAINT-GOBAIN GLASS FRANCEInventors: Guillaume Bignon, Nicolas Nadaud, Binh Tran, Se-Jong Kim
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Publication number: 20110236703Abstract: Provided is a method of preparing a film including the steps of providing a polymer substrate, depositing a metal layer on the polymer substrate in a metallization chamber, removing the metallized film from the metallization chamber, and applying a topcoat to said metal layer within 1 week of depositing the metal layer on the polymer substrate. A film produced by such a method exhibits improved barrier properties, such as improved water-vapor transmission rates.Type: ApplicationFiled: September 9, 2009Publication date: September 29, 2011Inventor: Dennis E. McGee
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Publication number: 20110159205Abstract: A coated string for a stringed device which includes a coating applied to the surface of the string. The coating includes a base layer bonded to the surface of the string and an at least partially transparent low-friction top coat applied to the base layer. The base layer includes heat activated pigments that change color when heated above a color shifting temperature. In one embodiment, the color of the pigment in one area contrasts with the color of the pigment in an adjacent area without otherwise affecting the low-friction surface of the coating. The areas of different color created in locations along the length of the low-friction coated string.Type: ApplicationFiled: March 4, 2011Publication date: June 30, 2011Applicant: INNOVATECH, LLCInventor: Bruce Nesbitt
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Publication number: 20100311614Abstract: An immobilizing device for biological material comprises a rigid support (12) carrying a substrate layer (20, 20?) of polymer having biological immobilizing properties, e.g. for amino and nucleic acids. Substantially solid ultra-thin substrate layers (20?) having a thickness less than about 5 micron, preferably between about 0.1 and 0.5 micron, and microporous, ultra-thin substrate layers (20?) having a thickness less than about 5 micron, preferably less than 3 micron, 2 or 1 micron are shown, which may be segmented by isolating moats M. The substrate layer is on a microscope slide (302), round disc (122), bio-cassette, at the bottom of a well of a multiwell plate, and as a coating inside a tube. Fluorescence or luminescence intensity and geometric calibration spots (420) are shown. Reading is enhanced by the intensity calibration spots (420) to enable normalization of readings under uneven illumination conditions, as when reading by dark field, side illumination mode.Type: ApplicationFiled: June 15, 2010Publication date: December 9, 2010Applicant: AVANTRA BIOSCIENCES CORPORATIONInventors: Jean I. Montagu, Roger Dowd, David Root
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Patent number: 7744955Abstract: A method of making a coated article including a transparent conductive oxide (TCO) film supported by a glass substrate is provided. In certain example embodiments, the coated article including the TCO film on the glass substrate is thermally tempered in a tempering furnace. In certain example embodiments, during tempering flame(s) are provided proximate the exposed surface of the TCO in order to burn off excess oxygen near the TCO surface thereby preventing or reducing oxidation of the TCO during the tempering process. A coated article, that is thermally tempered, made by such a product is also provided.Type: GrantFiled: August 2, 2005Date of Patent: June 29, 2010Assignee: Guardian Industries Corp.Inventors: Richard Blacker, Cory Richardson, Alexey Krasnov
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Publication number: 20100143724Abstract: Corrosion resistant metallized films and methods of making the same are disclosed.Type: ApplicationFiled: March 24, 2006Publication date: June 10, 2010Inventor: Michael A. Johnson
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Publication number: 20090064987Abstract: A grate apparatus configured to support a cooking utensil over a flame of a heat source on a cooktop stove. The grate apparatus includes an outer portion with a support surface configured to support the cooking utensil. The support surface includes a first coating. A plurality of protrusions is configured to support the cooking utensil. A portion of the plurality of protrusions is configured to be disposed closer to the flame of the heat source than is an entirety of the support surface. The plurality of protrusions includes a second coating different than the first coating.Type: ApplicationFiled: September 10, 2007Publication date: March 12, 2009Inventor: Paul Bryan Cadima
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Publication number: 20090011254Abstract: Provided is a release film, including a plastic film substrate, a surface modification layer formed on a single surface or both surfaces of the plastic film substrate by radiating a flame of a fuel gas including an organosilicon compound onto the single surface or both surfaces, and a silicone release layer composed of a cured product of a curable silicone composition, in which the silicone release layer is provided on top of the surface modification layer. The release film exhibits excellent adhesion between the silicone release layer and the plastic film substrate.Type: ApplicationFiled: July 3, 2008Publication date: January 8, 2009Applicant: Shin-Etsu Chemical Co., Ltd.Inventors: Kenji Yamamoto, Tsutomu Nakajima, Masahiko Ogawa
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Patent number: 7455883Abstract: A substrate is coated with a layer(s) or coating(s) that includes, for example, amorphous carbon in a form of diamond-like carbon (DLC). The DLC is then subjected to flame pyrolysis in order to cause the contact angle ? thereof to decrease.Type: GrantFiled: October 19, 2004Date of Patent: November 25, 2008Assignee: Guardian Industries Corp.Inventors: Rudolph Hugo Petrmichl, Joseph M. Bienkiewicz, Scott V. Thomsen
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Patent number: 7410675Abstract: The invention relates to the use of a polyolefinic film, with at least one layer, which is made from polyolefinic polymers, whereby said polyolefinic film comprises a bonding layer as outer layer. Said bonding layer contains at least 50 wt. % based on the weight of the layer of a maleic anhydride modified polyolefin. The film is used for printing, metallising or coating.Type: GrantFiled: May 9, 2001Date of Patent: August 12, 2008Assignee: Trespaphan GmbHInventors: Detlef Busch, Joachim Jung
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Patent number: 7399503Abstract: Process for producing a multilayer coating, in which a first coating (A) has applied to it a subsequent coating material (B) which is then cured involves selecting and/or modifying the first coating (A) and/or selecting the coating material (B) in such a way that the quotient (Q) formed from the surface energy of the second coating (B) and the surface energy of the first coating (A) is less than or equal to 1, and its use.Type: GrantFiled: January 30, 2004Date of Patent: July 15, 2008Assignee: BASF Coatings AGInventors: Klaus Holzapfel, Peter Mayenfels, Hubert Baumgart, Theodora Dirking
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Publication number: 20080145653Abstract: A unique primer emulsion chemistry yields excellent adhesion of polyethylene terephthalate (PET)resin to clay coated paperboard (with high starch content) at reduced coatweights of the primer emulsion and the resin as compared to other primer and tie-resin chemistries currently employed for moisture barrier applications. A primer used for adhesion enhancement is an ammonium catalyzed, self-crosslinking copolymer of ethylene-vinyl acetate with N-methylol acryl amide functional groups attached to a polymer backbone. Use of the primer in amounts up to about 0.5 pounds per ream permits PET coatweights of as low as 10-12 lbs per ream and lower for some applications.Type: ApplicationFiled: August 15, 2007Publication date: June 19, 2008Inventors: Ladislav Bednarik, Vivek Rohatgi, David V. Reed
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Publication number: 20080008829Abstract: This invention relates to a method of making a coated article for use in insulating glass (IG) window units, vehicle windows, or the like. The coated article typically includes a low-E coated article, including a low-E (low emissivity) coating supported by a glass substrate. In certain example embodiments, rapid heating (not sufficient for tempering or heat bending) of the coated article is utilized in order to reduce the emissivity and/or sheet resistance of the coated article without significantly damaging the infrared (IR) reflecting layer(s) of the coating, thereby activating the coated article. The glass of the coated article does not become too hot during such rapid heating.Type: ApplicationFiled: July 7, 2006Publication date: January 10, 2008Applicants: C.R.V.C.Inventors: Richard Blacker, Gerald Worley, Bernd Disteldorf
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Patent number: 7282238Abstract: A coherent material is formed on a substrate (10) by providing a precursor suspension (14) in which particulates are suspended in a carrier fluid, and directing the precursor suspension (14) at the substrate (10) from a first source (12). Generally contemporaneously with application of the deposited precursor suspension (14) to the surface, hot gases, e.g. hot gases produced by a flame (16), are directed at the substrate (10) from a remote second source (18) to fuse the particulates into the coherent material.Type: GrantFiled: June 27, 2001Date of Patent: October 16, 2007Assignee: nGimat Co.Inventors: Subramaniam Shanmugham, Andrew Tye Hunt, Girish Deshpande, Tzyy-Jiuan Jan Hwang, Erika Moore, Yongdong Jiang
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Patent number: 6939576Abstract: Coatings, particularly thin films, of polymeric material are produced in accordance with the invention by applying a finely divided aerosol of polymer solution to a substrate and substantially simultaneously applying an energy source to the applied solution to apply the solution. In cases where the polymer is cross-linking, the energy source assists in cross-linking of the polymer. The preferred energy source is a flame that may optionally or desirably deposit material along with the polymer spray. One particular aspect of the invention is directed to production of polyimide films. In accordance with another aspect of the invention, the co-deposition process is used to provide thin polysiloxane coatings on glass and other substrates.Type: GrantFiled: June 27, 2001Date of Patent: September 6, 2005Assignee: nGimat Co.Inventors: Girish Deshpande, Andrew Tye Hunt, Subramaniam Shanmugham, Eric J. Yurtkuran, Todd Polley, Miodrag Oljara, Tzyy-Jiuan Jan Hwang, Aimee Poda, George Neuman
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Patent number: 6753088Abstract: A method for at least locally providing an article coated with an organic coating with a layer of readily deformable sealing material (so-called compound), which involves a layer of an intermediate of the compound being applied to the coating layer, after which the article is temporarily kept at an elevated temperature in order to form the compound from its intermediate, wherein the coating layer of the article comprises a polyethylene terephthalate and the compound is chosen from the group consisting of urethanes, amides, mixtures thereof and heteropolymers thereof, and in that the free surface of the coating layer prior to the application of the intermediate of the compound, at least at the location where this intermediate is applied, is briefly subjected to a processing operation from the group of equivalent processing operations comprising a flame treatment in the course of which the coating layer does not melt.Type: GrantFiled: May 24, 2001Date of Patent: June 22, 2004Assignee: Corus Technology BVInventors: Renauld Robert Belvroy, Jan Willem Van Veenen
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Publication number: 20040110012Abstract: A process or preparing a coating composition which involves forming a hydrolysis product is described.Type: ApplicationFiled: September 29, 2003Publication date: June 10, 2004Inventors: Peter Bier, Peter Capellen
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Publication number: 20030175421Abstract: A process of cleaning a component following a forming operation that has left a residue on the component surface. The process comprises a thermal treatment during which the surface of the component is subjected to a controlled open flame, preferably in the presence of a limited amount of excess oxygen. Residues can be removed by the open flame to the extent that adhesion of a coating to the component surface can be greatly enhanced. Surface residue levels prior to the thermal treatment can be reduced by the use of lubricants prepared by diluting with de-ionized water or reverse osmosis water, thereby further increasing the likelihood of a residue-free surface having optimal adhesion properties. Under some circumstances, residue levels can be sufficiently reduced with the use of lubricants diluted with de-ionized or reverse osmosis water such that the thermal treatment can be omitted.Type: ApplicationFiled: December 13, 2002Publication date: September 18, 2003Applicant: DELPHI TECHNOLOGIES, INC.Inventors: Kurt F. O'Connor, Larry William Houk, Derek S. Ferraro, Mary A. Beam, Larry G. Hyman, Henry M. Sanftleben, B. Samuel Platt
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Patent number: 6503989Abstract: A monolayer polyolefin-based printable article includes 0.1 to 5% by weight of at least one polyaminoalkylene, and is characterized in that it has been treated by means of an oxidative surface treatment, such as a corona treatment. A process for the manufacture of a polyolefin-based printable article, according to which at least one surface region of the article, including at least one polyolefin and from 0.1 to 5% by weight of at least one polyaminoalkylene, involves subjecting the region to an oxidative surface treatment. A printing process, according to which a polyolefin-based article, including from 0.1 to 5% by weight of at least one polyaminoalkylene and treated by means of an oxidative surface treatment, utilizes an electrophotography technique to print on the article.Type: GrantFiled: July 24, 2000Date of Patent: January 7, 2003Assignee: Solvay (Societe Anonyme)Inventor: Zdenek Hruska
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Patent number: 6482473Abstract: A composition for increasing the dissipation of heat from one portion of a surface when heat is applied to another portion of the same surface. The preferred composition is a gel or paste with high water content and a thickener of a mineral clay in a colloidal suspension. The invention finds particular use in welding and soldering processes which are carried out adjacent heat sensitive materials.Type: GrantFiled: November 20, 2000Date of Patent: November 19, 2002Inventors: Kenneth R. Hallo, John L. Sheld
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Patent number: 6419992Abstract: A zinc coating directly covers a bare ferrous base of parking meter housing parts. A non-epoxy thermosetting electrically insulating organic non-epoxy powder coating directly covers the zinc coating. The organic coating is directly applied to the zinc coating by electrostatically charging the powder and parts with opposite d.c. voltage polarities and by heating the powder so it adheres to and covers the zinc coating. Alternatively, the base is zinc, directly covered by the organic powder coating.Type: GrantFiled: June 14, 2000Date of Patent: July 16, 2002Inventor: Scott Jay Lewin
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Publication number: 20020018860Abstract: A process for modifying the surface of a substrate containing a polymeric material by contacting the surface with the modifying agent to bond the modifying agent to the surface the process comprising providing a solution of the modifying agent in a solvent and subjecting the solution of the modifying agent to a zone of elevated temperature to vaporize the solvent and provide diffuse contact between the modifying agent and the surface of the substrate.Type: ApplicationFiled: February 12, 2001Publication date: February 14, 2002Inventors: Con Filippou, Wojciech S. Gutowski, David Proctor, Mark Spicer
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Patent number: 6311521Abstract: A raw material mixture, which has a glass composition containing a salt or an oxide of a flame reaction metal, is heated, and an intermediate base material, in which the salt of the flame reaction metal, or the like, has been thermally decomposed and which is in a temporary sintered state or a fused glass state, is thereby formed. The intermediate base material is ground, and a ground material is thereby obtained. The ground material is mixed together with a liquid and, optionally, a binder, and a viscous flame reaction material is thereby formed. The viscous flame reaction material is supported on a substrate and heated to a temperature, which is not lower than a vitrification melting temperature of the viscous flame reaction material. In this manner, the flame reaction material is fusion bonded to the substrate. Generation of a thermal decomposition gas in the baking step is thus restricted, and the carrying of the flame reaction material on the substrate is carried out appropriately.Type: GrantFiled: July 7, 1998Date of Patent: November 6, 2001Assignee: Tokai CorporationInventors: Hideo Mifune, Masato Seki
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Patent number: 6294222Abstract: A method of attaching a substantially uniform distribution of particulates to individual exposed surfaces of a matrix of fibrous material. The method includes the following steps: 1) electrically charging a matrix of fibrous material having individual exposed surfaces to create a substantially uniform distribution of charged sites at the exposed surfaces; 2) applying particulates to the charged matrix of fibrous material so that at least some particulates adhere at the charged sites; and 3) attaching particulates adhering to the fibrous material at charged sites by substantially non-transient bonding.Type: GrantFiled: June 10, 1996Date of Patent: September 25, 2001Assignee: Kimberly-Clark Worldwide, Inc.Inventors: Bernard Cohen, Judith Katherine Faass, Lamar Heath Gipson, Lee Kirby Jameson
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Patent number: 6225361Abstract: The invention provides expanded hollow micro sphere composite beads and a process for producing the beads. According to the invention, finely divided calcium carbonate can be uniformly deposited on expanded hollow thermoplastic polymer micro spheres by a simple procedure without incurring breakage of the expanded micro spheres so that the scattering of beads can be effectively inhibited. The preferred production process comprises admixing expanded hollow thermoplastic polymer micro spheres (A), with colloidal calcium carbonate (B) which has been surface-activated with a surface-treating agent or dispersing agent, e.g. a fatty acid series or polymer acid series compound. The admixing can be typically effected by dry-blending, preferably at a temperature of about 50-100° C.Type: GrantFiled: April 6, 2000Date of Patent: May 1, 2001Assignees: Akzo Nobel N.V., Japan Fillite Co., Ltd.Inventor: Takayuki Nakajima
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Patent number: 6168834Abstract: A method for increasing the dissipation of heat from one portion of a surface when heat is applied to another portion of the same surface. The preferred composition is a gel or paste with high water content and a thickener of a mineral clay in a colloidal suspension. The invention finds particular use in welding and soldering processes which are carried out adjacent heat sensitive materials.Type: GrantFiled: March 26, 1999Date of Patent: January 2, 2001Inventors: Kenneth R. Hallo, John L. Shcld
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Patent number: 6162487Abstract: A medical device of metallic or non-metallic material coated with a combination of antiseptics and a method for coating such an implant with a combination of antiseptics is provided. Different combinations of antiseptics can be used for different types of medical devices depending on the spectrum of organisms that cause the infections related to each device. The combination of different antiseptics has a synergistic effect against certain bacteria and fungi. The combination of antiseptic can be applied to the surface of a metallic device by dissolving the combination of antiseptics and a polymeric sticking agent in an acid solution to form an antiseptic solution, and applying the antiseptic solution, in an effective concentration to inhibit the growth of bacterial and fungal organisms, to at least a portion of the surfaces of the medical device.Type: GrantFiled: March 27, 1997Date of Patent: December 19, 2000Assignee: Baylor College of MedicineInventor: Rabih O. Darouiche
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Patent number: 6159531Abstract: A multi-step method for surface modification of a medical device having at least one surface exposed to tissue and/or blood. The steps comprise a low temperature plasma treatment of the said surface to provide a plasma deposited layer having functional groups. A chemical treatment of the plasma deposited layer using multifunctional linkers establishes covalent bonds with the plasma deposited layer. A bioactive/biocompatible agent react with the multifunctional linkers so that molecules thereof are covalently bound to said surface.Type: GrantFiled: August 30, 1999Date of Patent: December 12, 2000Assignee: CardioVasc, Inc.Inventors: Mai Huong Dang, Phillip Chiu
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Patent number: 6143354Abstract: A method of modifying the surface characteristics of a substrate, particularly a polymeric material. The method involves grafting ethylenically unsaturated monomers and attaching biomolecules, such as heparin, to the surface of the substrate, such as a polymeric material, in one step using an oxidizing metal, such as ceric ions.Type: GrantFiled: February 8, 1999Date of Patent: November 7, 2000Assignee: Medtronic Inc.Inventors: Edouard Koulik, Michel Verhoeven, Patrick Cahalan, Linda Cahalan
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Patent number: 6139585Abstract: A bioactive bone mineral carbonated nano-crystalline apatite is chemically bonded to a variety of substrates, including implantable prostheses. This coating is applied uniformly to substrate surfaces of varying geometry and surface textures. It is firmly secured to the substrate and encourages rapid and effective bone ingrowth. The coating is applied by immersing the substrate in an aqueous solution containing calcium, phosphate and carbonate ions. Other ions, such as sodium, potassium, magnesium, chloride, sulfate, and silicate, may optionally be present in the solution. The solution is exposed in a controlled environment when it reacts with the substrate to form the coating.Type: GrantFiled: March 11, 1998Date of Patent: October 31, 2000Assignee: Depuy Orthopaedics, Inc.Inventor: Panjian Li
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Patent number: 6136891Abstract: Composite particles having a core consisting of an organic polymer and a coating including at least one aluminum, silicon, zirconium and/or transition metal oxide and/or hydroxide, and optionally containing calcium carbonate, as well as methods for preparing same, are disclosed. The use of said composite particles for preparing hollow particles with a shell of the same kind as the above-mentioned coating is also disclosed. Finally, the use of said hollow composite particles as fillers or additives in plastics and elastomers is disclosed.Type: GrantFiled: January 8, 1999Date of Patent: October 24, 2000Assignee: Rhodia ChimieInventors: Thierry Chopin, Dominique Dupuis, Dominique Labarre, Gilles Mur
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Patent number: 6131580Abstract: Template-imprinted structures 10 are provided having at least one template-imprinted surface 12 defining indentations 14 that are capable of specifically binding cells and/or molecules, such as macromolecules including proteins, peptides and nucleic acids. Presently preferred embodiments of the template-imprinted structures include medical prostheses, such as artificial joints and heart valves, having surface indentations that specifically bind proteins and/or cells that enhance the biocompatibility of the prosthesis, thereby making it less likely that the prosthesis will be rejected by the body. Methods are also provided for making the template-imprinted structures of the present invention.Type: GrantFiled: April 15, 1999Date of Patent: October 17, 2000Assignee: The University of WashingtonInventors: Buddy D. Ratner, Huaiqiu Shi
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Patent number: 6120847Abstract: A method is provided for eliminating surface imperfections on a medical device having a drug release coating including a therapeutic substance in a polymeric carrier disposed on at least a portion of the medical device. The medical device is preferably a stent including wire-like members interconnected to form struts with open interstices therebetween. A therapeutic substance incorporate into a polymeric carrier is disposed on the surface of the stent through which process imperfections including polymeric fibers, polymeric particles or other polymeric surface aberrations or imperfections are formed. This imperfections are eliminated by contacting the polymeric coating with a vaporized solvent for a specified period of time.Type: GrantFiled: January 8, 1999Date of Patent: September 19, 2000Assignee: SciMed Life Systems, Inc.Inventors: Dachuan Yang, Carmen Jacob, Lixiao Wang
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Patent number: 6120536Abstract: A coating and method for implantable open lattice metallic stent prostheses are disclosed. The coating includes a relatively thin layer of biostable elastomeric material containing an amount of biologically active material, particularly heparin, dispersed in the coating in combination with a non-thrombogenic surface. In one embodiment, the surface is provided with sites of high electronegativity species by coating with fluorosilicone which aid in controlling elution, particularly the initial release rate, and reduced thrombogenic activity. Other non-thrombogenic outer layers for heparin such as covalently bound polyethylene glycol (PEG) are also disclosed.Type: GrantFiled: June 13, 1996Date of Patent: September 19, 2000Assignee: Schneider (USA) Inc.Inventors: Ni Ding, Michael N. Helmus
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Patent number: 6113636Abstract: Approaches are described for depositing antimicrobial elemental metal and/or metal compounds within a medical article. The medical article generally includes biocompatible material that can contact bodily fluids. In particular, antimicrobial elemental metal can be deposited on and in a biocompatible material such as tissue. Chemical, photochemical and electrochemical processes for depositing elemental metal are described. In addition, an antimicrobial metal compound can be deposited by precipitation of the compound from a solution of metal cation. Antimicrobial metal deposits may reduce the incidence of infection associated with contacting a recipient medical patient with the biocompatible material.Type: GrantFiled: November 20, 1997Date of Patent: September 5, 2000Assignee: St. Jude Medical, Inc.Inventor: Matthew F. Ogle
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Patent number: 6110204Abstract: The present invention relates to an implant for use in the human body, an implant substrate being coated with a material which contains chemical compounds between one or more metals (M) of group IV A of the periodic system, nitrogen (N) and oxygen (O), 2 to 45% of the volume in the coating material being formed by voids whose sizes range from (0.4 nm).sup.3 to (50 nm).sup.3, and the remaining volume having a composition of a metal of group IV A of the periodic system to nitrogen to oxygen of 1:(0.1 to 1.7):(0.1 to 1.7), a material having formula MN.sub.x O.sub.y (wherein x,y=0.1-1.7) resulting.The invention also relates to the use of this implant for implantation into the animal or human body.Type: GrantFiled: February 9, 1998Date of Patent: August 29, 2000Assignee: Huber & SchusslerInventors: Miladin Lazarov, Isabella Mayer
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Patent number: 6099852Abstract: This invention provide silicone-based, biomedical devices that exhibit improved wettability as well as biocompatability through the use of functional silane agents. More specifically, the invention provides devices at least one surface of which has a functional silane coupling agent and hydrophilic polymer.Type: GrantFiled: September 23, 1998Date of Patent: August 8, 2000Assignee: Johnson & Johnson Vision Products, Inc.Inventor: James J. Jen
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Patent number: 6099563Abstract: Disclosed is a method of enhancing the biocompatibility of a substrate by providing the substrate with a continuous bio-active surface coating. This method includes applying to the substrate a first coating which includes an aqueous dispersion or emulsion of a polymer containing an organic acid functional group and an excess of a polyfunctional cross-linking agent which is reactive with the organic acid groups of the polymer. A continuous bio-active surface coating is then formed over the dried first coating by applying thereover a bio-active agent containing an organic acid functional group or metal salt thereof. The first and second coatings are then dried to covalently bond the organic acid functional groups of the bio-active agent to the polymer through the excess unreacted polyfunctional cross-linking agent.Type: GrantFiled: December 11, 1998Date of Patent: August 8, 2000Assignee: Boston Scientific CorporationInventor: Sheng-Ping Zhong