Identified Electron Acceptor Or Desensitizer Containing Patents (Class 430/412)
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Patent number: 8173021Abstract: The present invention relates to methods for the preparation of functionalized sulfated cellulose membranes. In particular, the present invention relates to the preparation of sulfated cellulose membranes under specific reaction conditions allowing to provide a sulfated cellulose membrane useful for pseudo-affinity purification. In another aspect, the present invention relates to the sulfated cellulose membrane itself as well as its use for isolation of proteinaceous compositions. Finally, the present invention provides a method for isolating whole virus, virus proteins or heparin binding molecules comprising the step of affinity purification using the sulfated cellulose membrane according to the present invention.Type: GrantFiled: October 16, 2009Date of Patent: May 8, 2012Assignee: Max-Planck-Gesellschaft zur Förderung der Wissenschaften e.V.Inventors: Michael Wolff, Udo Reichl, Lars Opitz
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Patent number: 7829252Abstract: An imaging member having an enhanced anti-curl back coating is disclosed. The anti-curl back coating comprises a liquid oligomer. Additionally, a slip agent can also be included. The resulting anti-curl back coating contains little to no residual solvent, shows improved resistance to wear and ozonolysis, and increased lubricity to prevent static charge built-up.Type: GrantFiled: September 7, 2005Date of Patent: November 9, 2010Assignee: Xerox CorporationInventor: Robert C. U. Yu
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Patent number: 6593123Abstract: Methods are provided for large-scale purification of recombinant AAV (rAAV) virions that were produced in the absence of infectious adenovirus. Preferably, the rAAV is produced in a host cell line via triple-transfection with an accessory function vector, an AAV vector, and an AAV helper vector. The methods include preparing a lysate from the host cell line and passing that lysate over various combinations of ion exchange chromatography media and/or affinity chromatography media. The affinity chromatography medium is an AAV receptor or an antibody with binding affinity for AAV, e.g., heparin sulfate. A variety of cation exchange and anion exchange media are contemplated by the present invention. In certain embodiments, optional purification steps may be included, such as filtering the lysate through one or more filters, or treating the lysate with a nuclease.Type: GrantFiled: August 7, 2000Date of Patent: July 15, 2003Assignee: Avigen, Inc.Inventors: John Fraser Wright, Quang Qu
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Patent number: 4971899Abstract: Direct positive photographic films are disclosed having novel density enhancers of the formula ##STR1## wherein A is oxygen or sulfur, and B is selected from the group consisting of hydrogen, alkyl haloalkyl, hydroxyalkyl, alkylamino and alkoxy. Photographic materials coated with emulsions having these density enhancers display good optical density while maintaining high speed capability.Type: GrantFiled: May 5, 1989Date of Patent: November 20, 1990Assignee: Sun Chemical CorporationInventors: Steven R. Gallo, John Abbruzzese, Adelberto Aguero
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Patent number: 4820625Abstract: A direct positive silver halide photographic material comprising a support having thereon at least one silver halide emulsion layer comprising a prefogged direct-positive silver halide emulsion, preferably one having a chloride content of at least 70 mol%, said emulsion layer or a hydrophilic colloid layer adjacent to said emulsion layer containing at least one compound represented by the following general formula (I) and, optionally, a specified organic desensitizer, ##STR1## wherein Z.sub.Type: GrantFiled: September 21, 1987Date of Patent: April 11, 1989Assignee: Fuji Photo Film Co., Ltd.Inventors: Naomi Saeki, Nobuaki Inoue, Toshinao Ukai, Yuji Mihara
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Patent number: 4814263Abstract: A direct-positive silver halide emulsion comprising fine grain reduction and gold surface fogged silver halide grains containing an electron-trapping effective amount of at least one Group VIII metal dopant, at least 75% by weight of all silver halide grains in said emulsion being silver halide grains wherein at least 80 mole percent of the halide within said grains is chloride.Type: GrantFiled: July 21, 1987Date of Patent: March 21, 1989Assignee: Minnesota Mining and Manufacturing CompanyInventor: Philip Hine
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Patent number: 4756995Abstract: A direct reversal silver halide photographic light-sensitive material is disclosed. The material is comprised of a support having thereon a silver halide emulsion layer having silver halide grains, the surface of which is preliminarily fogged, rhodium as a desensitizer, and a dye having an absorption maximum within the range of from 470 to 520 nm. The dye is represented by the general formula (I): ##STR1## The substituents within general formula (I) are defined in the specification. The material has improved safety with respect to visible safe light and does not suffer color stain after photographic development processing. Further, the dye is stable in a solution state during processing.Type: GrantFiled: November 21, 1985Date of Patent: July 12, 1988Assignee: Fuji Photo Film Co., Ltd.Inventors: Tetsuro Kojima, Nobuaki Inoue, Tadashi Ikeda
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Patent number: 4395483Abstract: A high contrast, chemically fogged direct positive type silver halide photosensitive material is described containing at least one ammine complex salt selected from those including cobalt, nickel, ruthenium or chromium, by which the contrast in the lower optical density region is improved while retaining superior Dmax and sensitivity.Type: GrantFiled: February 26, 1982Date of Patent: July 26, 1983Assignee: Fuji Photo Film Co., Ltd.Inventors: Terumi Matsuda, Shoji Ishiguro, Shigenori Moriuchi, Yoshiaki Suzuki
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Patent number: 4376817Abstract: Direct-positive photographic material having at least one layer which contains a silver halide emulsion surface-fogged by chemical means or by exposure and a tri-nuclear cyanine dye, which has the formula ##EQU1## in which A.sub.1 is .dbd.CH-- or .dbd.CH--CH.dbd.CH--, Z.sub.1 is a monocyclic or polycyclic heterocyclic radical which is linked by a double bond to the adjacent methine group, Z.sup..sym. is a positively charged radical which is mesomeric to Z.sub.1 and is linked by a single bond to the adjacent methine group, Z.sub.2 --is a nitrogen-heterocyclic radical which has its single positive charge on the nitrogen atom and Z.sub.3 .dbd. is a radical which has no charge on the nitrogen atom and is mesomeric to Z.sub.2, at least one of the radicals Z.sub.Type: GrantFiled: July 27, 1981Date of Patent: March 15, 1983Assignee: Ciba-Geigy AGInventors: Rolf Steiger, Jean F. Reber
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Patent number: 4311786Abstract: Direct-positive photographic material which has at least one layer which contains a silver halide emulsion surface-fogged by chemical means or by exposure and, as a sensitizer, a trinuclear tetramethinecyanine dye in which all or some of the methine hydrogen atoms have been replaced by fluorine, chlorine, bromine or iodine atoms. The novel trinuclear tetramethinecyanine dyes impart an excellent blue-sensitivity to the photographic materials. Furthermore, high maximum densities and very low minimum densities are achieved.Type: GrantFiled: July 11, 1980Date of Patent: January 19, 1982Assignee: Ciba-Geigy AGInventors: Rolf Steiger, Jean F. Reber
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Patent number: 4287296Abstract: Direct positive silver halide emulsions are provided which contain fogged silver halide grains the said grains being heterodisperse and containing silver iodide in an amount of more than 10 mole % and at most 20 mole % relative to the total amount of silver halide. The emulsions have increased sensitivity and reduced gradation which is suitable for continuous tone reproduction.Type: GrantFiled: November 20, 1973Date of Patent: September 1, 1981Assignee: Agfa-Gevaert, N.V.Inventors: Willy J. Vanassche, Herman A. Pattyn, Erik Moisar, Sieghart Klotzer
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Patent number: 4273862Abstract: Direct-positive silver halide photographic sensitive materials of high sensitivity and capable of forming a high-contrast image are obtained by incorporating anion-type cyanine dyes having a polarographic oxidation halfwave potential not less positive than +0.4 V in externally fogged direct-positive silver halide emulsions containing not less than 70 mole-% of bromide. Additional incorporation of a development accelerator such as 2-mercaptoimidazoline improves developability.Type: GrantFiled: September 24, 1979Date of Patent: June 16, 1981Assignee: Mitsubishi Paper Mills, Ltd.Inventors: Akio Yoshida, Seigo Ebato