Preparing Hydrocarbon Patents (Class 435/166)
  • Patent number: 11204271
    Abstract: A method for alternative fuel life-cycle tracking includes electronically receiving, at a remote server, fuel data of fuel in a first container. The fuel comprises first and second batches. The fuel data includes first and second sets of alternative fuel identifiers (AFIs) associated with, respectively, a first unit of the first batch and a second unit of the second batch. The method further includes electronically receiving, at the remote server, a transfer volume of the fuel being transferred to a second container. The method further includes electronically transferring, at the remote server, first and second subsets, respectively, of the first and second sets of AFIs to be associated with the second container. The transfer of the first and second subsets is based on the transfer volume and a proportion of the first unit to the second unit.
    Type: Grant
    Filed: December 6, 2016
    Date of Patent: December 21, 2021
    Assignee: Gilbarco Inc.
    Inventors: Rodger K. Williams, Edward A. Payne
  • Patent number: 11072805
    Abstract: The invention relates to a two phase fermentation process for producing an organic compound, in particular an isoprenoid and to a bioreactor comprising a two phase fermentation system for producing an organic compound.
    Type: Grant
    Filed: January 25, 2019
    Date of Patent: July 27, 2021
    Inventors: Antonius Cornelis Johannes Matheus Janssen, Joannes Gerardus Theodorus Kierkels, Georg Friedrich Lentzen
  • Patent number: 11041175
    Abstract: The invention relates to a two phase fermentation process for producing an organic compound, in particular an isoprenoid and to a bioreactor comprising a two phase fermentation system for producing an organic compound.
    Type: Grant
    Filed: January 25, 2019
    Date of Patent: June 22, 2021
    Inventors: Antonius Cornelis Johannes Matheus Janssen, Joannes Gerardus Theodorus Kierkels, Georg Friedrich Lentzen
  • Patent number: 10633675
    Abstract: The invention relates to the production of one or more terpenoids through microbial engineering, and relates to the manufacture of products comprising terpenoids.
    Type: Grant
    Filed: July 10, 2018
    Date of Patent: April 28, 2020
    Assignees: Massachusetts Institute of Technology, National University of Singapore
    Inventors: Parayil K. Ajikumar, Gregory Stephanopoulos, Heng Phon Too
  • Patent number: 10533193
    Abstract: The document provides methods for biosynthesizing isobutene using one or more isolated enzymes such as one or more of a hydratase such as an enzyme classified under EC 4.2.1.- and a decarboxylating thioesterase, or using recombinant host cells expressing one or more such enzymes.
    Type: Grant
    Filed: August 5, 2014
    Date of Patent: January 14, 2020
    Assignee: INVISTA NORTH AMERICA S.A.R.L.
    Inventors: Alex Van Eck Conradie, Adriana Leonora Botes
  • Patent number: 10519433
    Abstract: The present disclosure provides novel polypeptides with 3-buten-2-ol dehydratase activity, polypeptides with catalytic activity in the conversion of 3-methyl-3-buten-2-ol to isoprene, and crystal structure data for one of such polypeptides. Methods of making and using the polypeptides and their related crystal structure data are also provided.
    Type: Grant
    Filed: February 29, 2016
    Date of Patent: December 31, 2019
    Assignee: INVISTA NORTH AMERICA S.A.R.L.
    Inventors: Nadia Kadi, Adriana L. Botes, Mihai Luchian Azoitei, Yih-En A. Ban, Daniela Grabs-Röthlisberger, Alexander Pisarchik, Alexandre Zanghellini, Eric Althoff
  • Patent number: 10385361
    Abstract: Provided herein are methods of producing (+)-manool comprising: contacting geranylgeranyl diphosphate with an copalyl diphosphate (CPP) synthase to form a (9S, 10S)-copalyl diphosphate wherein the CPP synthase comprises an amino acid sequence having at least 90%, 95%, 98%, 99% and 100% sequence identity to a polypeptide selected from the group consisting of SEQ ID NO: 1 and SEQ ID NO:2; and contacting the CPP with a sclareol synthase enzyme to form (+)-manool.
    Type: Grant
    Filed: June 30, 2016
    Date of Patent: August 20, 2019
    Assignee: Firmenich SA
    Inventors: Michel Schalk, Letizia Rocci
  • Patent number: 10214736
    Abstract: The present disclosure provides novel polypeptides with 3-buten-2-ol dehydratase activity, polypeptides with catalytic activity in the conversion of 3-methyl-3-buten-2-ol to isoprene, and crystal structure data for one of such polypeptides. Methods of making and using the polypeptides and their related crystal structure data are also provided.
    Type: Grant
    Filed: May 12, 2017
    Date of Patent: February 26, 2019
    Assignee: INVISTA North America S.à.r.l.
    Inventors: Eric Althoff, Nadia Kadi, Mihai Luchian Azoitei, Yih-En A. Ban, Daniela Grabs-Röthlisberger, Alexander Pisarchik, Alexandre Zanghellini, Adriana L. Botes
  • Patent number: 10072279
    Abstract: The present invention concerns a method for producing terpenes in fungi comprising the steps of (a) providing a modified terpene biosynthetic gene cluster inside a host cell, wherein one or more of the naturally occurring genes or promoters of the cluster have been replaced, truncated or removed, (b) providing a transcription factor inside the host cell, the transcription factor activating the terpene biosynthetic gene cluster; (c) cultivating said host in conditions allowing the expression of the transcription factor activating the cluster; and optionally (d) recovering the thus produced terpene product.
    Type: Grant
    Filed: May 13, 2013
    Date of Patent: September 11, 2018
    Assignee: Teknologian tutkimuskeskus VTT Oy
    Inventors: Kirsi Bromann, Mervi Toivari, Tiina Nakari-Setälä, Laura Ruohonen
  • Patent number: 10010807
    Abstract: Improvements in biological conversion processes and associated apparatuses are disclosed for the generation of useful end products such as ethanol, through metabolic pathways of C1-fixing bacteria that utilize, as a nutrient, a C1-carbon source from a C1-containing substrate such as an industrial waste gas. Particular aspects of the disclosure relate to the downstream recovery of ethanol and/or isopropanol from bleed and permeate streams and more particularly to performing such recovery with improved efficiency that can advantageously reduce capital (e.g., equipment) and/or operating (e.g., utility) costs. Particular aspects related to the downstream recovery of ethanol and/or isopropanol using a low pressure separator having an internal divider.
    Type: Grant
    Filed: February 3, 2017
    Date of Patent: July 3, 2018
    Assignee: LANZATECH NEW ZEALAND LIMITED
    Inventor: Michael Anthony Schultz
  • Patent number: 9957513
    Abstract: The present invention relates to the development of genetically engineered yeasts that can produce hydrocarbons in a controllable and economic fashion. More specifically the invention relates to the production of liquid alkanes and alkenes that can be used for liquid transportation fuels, specialty chemicals, or feed stock for further chemical conversion.
    Type: Grant
    Filed: August 21, 2017
    Date of Patent: May 1, 2018
    Assignee: BIOPETROLIA AB
    Inventors: Jens Nielsen, Verena Siewers, Paulo Alexandre Goncalves Teixeira, Yongjin Zhou, Nicolaas A. A. Buijs, Florian David
  • Patent number: 9890401
    Abstract: Methods and compositions, including nucleotide sequences, amino acid sequences, and host cells, for producing fatty alcohols are described.
    Type: Grant
    Filed: May 22, 2015
    Date of Patent: February 13, 2018
    Assignee: REG LIFE SCIENCES, LLC
    Inventors: Zhihao Hu, Vikranth Arlagadda
  • Patent number: 9879109
    Abstract: Provided are rubber compositions for tires capable of providing tire components and pneumatic tires that have the same level of fuel efficiency and wet grip performance (particularly, wet grip performance) as those of tire components and pneumatic tires containing conventional synthetic rubber, while satisfying the requirements for a sound material-cycle society. The present invention relates to rubber compositions for tires containing a biomass-derived rubber polymerized from an aromatic vinyl compound and a diene, the biomass-derived rubber having a pMC (percent modern carbon) measured in accordance with ASTM D 6866-10 of 1% or higher.
    Type: Grant
    Filed: September 6, 2013
    Date of Patent: January 30, 2018
    Assignee: SUMITOMO RUBBER INDUSTRIES, LTD.
    Inventors: Ryoji Kojima, Yuka Yokoyama, Masafumi Yoshino
  • Patent number: 9873895
    Abstract: The present invention relates to a method for generating 1,3-diene compounds through a biological process. More specifically, the invention relates to a method for producing 1,3-diene compounds (for example butadiene or isoprene) from molecules of the 3-hydroxyalk-4-enoate type or from 3-phosphonoxyalk-4-enoates.
    Type: Grant
    Filed: December 18, 2012
    Date of Patent: January 23, 2018
    Assignee: Scientist of Fortune S.A.
    Inventor: Philippe Marliere
  • Patent number: 9803220
    Abstract: The application describes a method for producing alkenes (for example propylene, ethylene, 1-butylene, isobutylene, isoamylene, butadiene or isoprene) from 3-hydroxy-1-carboxylic acids via 3-sulfonyloxy-1-carboxylic acids.
    Type: Grant
    Filed: October 24, 2013
    Date of Patent: October 31, 2017
    Assignees: Global Bioenergies, Scientist of Fortune, S.A.
    Inventors: Philippe Marliere, Maria Anissimova, Mathieu Allard
  • Patent number: 9751991
    Abstract: An eugenol, an abundant natural phenol and the primary component of clove oil, which is converted to a thermoset resin via a high yield, two-step reaction. Modest heating yields a thermoset material with thermal stability above 350° C., a glass transition temperature of 187° C. and water uptake of only 1.8%.
    Type: Grant
    Filed: April 16, 2015
    Date of Patent: September 5, 2017
    Assignee: The United States of America as Represented by the Secretary of the Navy
    Inventor: Benjamin G. Harvey
  • Patent number: 9534197
    Abstract: The present invention is a system for optimizing production of biomass. The system contains one or more growth modules under a shading element that diffuses light. Each of the growth modules has a plurality of vertical growth columns arranged on a bottom manifold. The biomass is grown within a liquid growth medium held within each of the vertical growth columns until it reaches a desired growth. The biomass is then harvested through gravitational flow of the biomass and the liquid growth medium out of the bottom of each growth column. The bottom manifold collects gravitational flow of the biomass and liquid growth media from each growth column and aggregates the output of each individual column into a collective output of the growth module.
    Type: Grant
    Filed: August 12, 2010
    Date of Patent: January 3, 2017
    Assignee: ALGETERNAL TECHNOLOGIES, LLC
    Inventors: Milton Hugh Morris, Katon Hughes Deal Morris, John Michael Harris, Michael Donavan Jochum, Jr.
  • Patent number: 9527038
    Abstract: A bioelectrochemical system includes an anode, a saline solution chamber, and a cathode. The anode is at least partially positioned within an anode chamber containing an aqueous reaction mixture including one or more organic compounds and one or more bacteria for oxidizing the organic compounds. The saline solution chamber contains a draw solution and is separated from the anode chamber by a forward osmosis membrane. Water diffuses across the forward osmosis membrane from the aqueous reaction mixture to the draw solution.
    Type: Grant
    Filed: July 11, 2012
    Date of Patent: December 27, 2016
    Assignee: UWM Research Foundation, Inc.
    Inventor: Zhen He
  • Patent number: 9518922
    Abstract: An arrangement for in situ measurement of at least one oxygen partial pressure within a solids heap, including: at least one measuring transducer arranged within the solids heap for locally registering oxygen partial pressure, wherein each measuring transducer is embodied to output a measurement signal representing oxygen partial pressure to a superordinated unit, which is arranged outside the solids heap and is embodied to receive and to process the measurement signals of each measuring transducer.
    Type: Grant
    Filed: August 1, 2011
    Date of Patent: December 13, 2016
    Assignee: Endress+Hauser Conducta GmbH+Co. KG
    Inventor: Lars Bondzio
  • Patent number: 9453244
    Abstract: The present invention relates to a method for producing a monoalkene comprising the step of enzymatically converting an alkyl monoester. The conversion preferably makes use of an enzyme which belongs to the group of terpene synthases or to the family of prenyltransferases. Moreover, the present invention relates to the use of a terpene synthase or of a prenyltransferase for enzymatically converting an alkyl monoester into a monoalkene.
    Type: Grant
    Filed: June 28, 2013
    Date of Patent: September 27, 2016
    Assignees: Global Bioenergies, Scientist of Fortune S.A.
    Inventors: Philippe Marlière, Maria Anissimova, Mathieu Allard
  • Patent number: 9447345
    Abstract: A partially digested biomass solids is converted in a fixed bed catalytic reduction reactor under hydrothermal catalytic condition with a supported metal catalyst having a high void fraction. The catalyst having high void fraction allows high permeability and extends reaction run time.
    Type: Grant
    Filed: October 3, 2013
    Date of Patent: September 20, 2016
    Assignee: Shell Oil Company
    Inventors: Joseph Broun Powell, John Anthony Smegal
  • Patent number: 9404130
    Abstract: The invention relates to the production of one or more terpenoids through microbial engineering, and relates to the manufacture of products comprising terpenoids.
    Type: Grant
    Filed: November 25, 2014
    Date of Patent: August 2, 2016
    Assignees: Massachusetts Institute of Technology, National University of Singapore
    Inventors: Parayil K. Ajikumar, Gregory Stephanopoulos, Heng Phon Too
  • Patent number: 9359624
    Abstract: The invention relates to recombinant expression of a taxadiene synthase enzyme and a geranylgeranyl diphosphate synthase (GGPPS) enzyme in cells and the production of terpenoids.
    Type: Grant
    Filed: July 17, 2013
    Date of Patent: June 7, 2016
    Assignees: Massachusetts Institute of Technology, National University of Singapore
    Inventors: Parayil K. Ajikumar, Gregory Stephanopoulos, Heng Phon Too
  • Patent number: 9206453
    Abstract: Biomass (e.g., plant biomass, animal biomass, and municipal waste biomass) is processed to produce useful intermediates and products, such as energy, fuels, foods or materials. For example, systems are described that can use feedstock materials, such as cellulosic and/or lignocellulosic materials, to produce an intermediate or product, e.g., by fermentation.
    Type: Grant
    Filed: November 21, 2012
    Date of Patent: December 8, 2015
    Assignee: XYLECO, INC.
    Inventors: Marshall Medoff, Harrison Medoff
  • Patent number: 9040271
    Abstract: According to the present invention, organic material is converted to biogas through anaerobic digestion and the biogas is purified to yield a combustible fluid feedstock comprising methane. A fuel production facility utilizes or arranges to utilize combustible fluid feedstock to generate renewable hydrogen that is used to hydrogenate crude oil derived hydrocarbons in a process to make transportation or heating fuel. The renewable hydrogen is combined with crude oil derived hydrocarbons that have been desulfurized under conditions to hydrogenate the liquid hydrocarbon with the renewable hydrogen. The present invention enables a party to receive a renewable fuel credit for the transportation or heating fuel.
    Type: Grant
    Filed: May 6, 2014
    Date of Patent: May 26, 2015
    Assignee: IOGEN Corporation
    Inventor: Brian Foody
  • Patent number: 9034629
    Abstract: The present disclosure identifies methods and compositions for modifying photoautotrophic organisms as hosts, such that the organisms efficiently produce alkanes, and in particular the use of such organisms for the commercial production of alkanes and related molecules. Other materials, methods, and compositions are also described.
    Type: Grant
    Filed: January 27, 2014
    Date of Patent: May 19, 2015
    Assignee: Joule Unlimited Technologies, Inc.
    Inventors: Frank Anthony Skraly, Ning Li
  • Publication number: 20150132809
    Abstract: The present invention provides for a system for increasing the production of a compound using an artificial positive feedback loop (APFL). In some embodiments, the system diverts a compound produced in a first metabolic pathway into a second metabolic pathway in order to produce a compound of interest.
    Type: Application
    Filed: January 27, 2015
    Publication date: May 14, 2015
    Applicant: THE REGENTS OF THE UNIVERSITY OF CALIFORNIA
    Inventor: Dominique Loque
  • Publication number: 20150125903
    Abstract: The present invention provides fungal xylanase and/or xylosidase enzymes suitable for use in saccharification reactions. The present invention provides xylanase and xylosidase enzymes suitable for use in saccharification reactions. The present application further provides genetically modified fungal organisms that produce xylanase(s) and/or xylosidase(s), as well as enzyme mixtures exhibiting enhanced hydrolysis of cellulosic material to fermentable sugars, enzyme mixtures produced by the genetically modified fungal organisms, and methods for producing fermentable sugars from cellulose using such enzyme mixtures. In some embodiments, the xylanase and xylosidase enzyme(s) are M. thermophila enzymes.
    Type: Application
    Filed: January 14, 2015
    Publication date: May 7, 2015
    Inventors: Nicholas John Agard, David Elgart, Jie Yang, Goutami Banerjee, Jeanne Bonomo Benoit, Dipnath Baidyaroy
  • Publication number: 20150126787
    Abstract: The present invention is directed to renewable compositions derived from fermentation of biomass, and integrated methods of preparing such compositions.
    Type: Application
    Filed: November 3, 2014
    Publication date: May 7, 2015
    Applicant: Gevo, Inc.
    Inventors: Patrick R. Gruber, Matthew W. Peters, Josefa M. Griffith, Yasin Al Obaidi, Leo E. Manzer, Joshua D. Taylor, David E. Henton
  • Publication number: 20150125906
    Abstract: The present invention relates to methods of degrading or converting biomass material enriched with hemicellulosic material into fermentable sugars.
    Type: Application
    Filed: January 14, 2015
    Publication date: May 7, 2015
    Inventors: Prashant Iyer, Harry Showmaker, Hui Xu, Kishore Rane
  • Patent number: 9006502
    Abstract: A process for the production of bio-oil from solid urban waste, comprising the following steps: a) subjecting said solid urban waste to liquefaction, obtaining a mixture including an oily phase consisting of bio-oil, a solid phase and an aqueous phase; b) subjecting the aqueous phase obtained in the liquefaction step a) to fermentation, obtaining a fermented biomass; c) feeding the fermented biomass obtained in the fermentation step b) to the liquefaction step a). The bio-oil (or bio-crude) thus obtained can be advantageously used in the production of biofuels which can be used as such or mixed with other motor vehicle fuels. Alternatively, this bio-oil (or bio-crude) can be used as such (biocombustible) or mixed with fossil combustibles (combustible oil, coal, etc.) for the generation of electric energy or heat.
    Type: Grant
    Filed: September 1, 2010
    Date of Patent: April 14, 2015
    Assignee: ENI S.p.A.
    Inventors: Aldo Bosetti, Daniele Bianchi, Giuliana Franzosi, Marco Ricci
  • Publication number: 20150099283
    Abstract: A method of producing patchoulol and 7-epi-?-selinene by contacting at least one polypeptide with farnesyl phyrophosphate (fpp). The method may be carried out in vitro or in vivo to produce patchoulol and 7-epi-?-selinene, compounds which can be useful in the field of perfumery.
    Type: Application
    Filed: December 19, 2014
    Publication date: April 9, 2015
    Applicant: FIRMENICH SA
    Inventors: Michel SCHALK, Fabienne DEGUERRY
  • Publication number: 20150099276
    Abstract: The present invention relates to the use of nucleic acid molecules coding for a bacterial xylose isomerase (XI), preferably coming from Clostridium phytofermentans, for reaction/metabolization, particularly fermentation, of recombinant microorganisms of biomaterial containing xylose, and particularly for the production of bioalcohols, particularly bioethanol, by means of xylose fermenting yeasts. The present invention further relates to cells, particularly eukaryotic cells, which are transformed utilizing a nucleic acid expression construct which codes for a xylose isomerase, wherein the expression of the nucleic acid expression construct imparts to the cells the capability to directly isomerize xylose into xylulose. Said cells are preferably utilized for reaction/metabolization, particularly fermentation, of biomaterial containing xylose, and particularly for the production of bioalcohols, particularly bioethanol.
    Type: Application
    Filed: December 16, 2014
    Publication date: April 9, 2015
    Inventors: Dawid BRAT, Eckhard BOLES, Marco KELLER, Beate ROTHER
  • Publication number: 20150093776
    Abstract: A method for producing metabolites of Crocus sativus (C. sativus) includes (i) selecting a cell line of C. sativus that produces one or more saffron metabolites in cell suspension culture, and (ii) growing the selected cell line in a suspension cell culture to produce the saffron metabolite.
    Type: Application
    Filed: April 19, 2013
    Publication date: April 2, 2015
    Inventors: Sung-Yong H. Yoon, Raymond E. B. Ketchum, Colby G. Caldwell
  • Publication number: 20150093797
    Abstract: Provided herein are compositions and methods for the heterologous production of acetyl-CoA-derived isoprenoids in a host cell. In some embodiments, the host cell is genetically modified to comprise a heterologous nucleotide sequence encoding an acetaldehyde dehydrogenase, acetylating (ADA, E.C. 1.2.1.10) and an MEV pathway comprising an NADH-using HMG-CoA reductase. In some embodiments, the host cell is genetically modified to comprise a heterologous nucleotide sequence encoding an ADA and an MEV pathway comprising an acetoacetyl-CoA synthase. In some embodiments, the genetically modified host cell further comprises one or more heterologous nucleotide sequences encoding a phosphoketolase and a phosphotransacetylase. In some embodiments, the genetically modified host cell further comprises a functional disruption of the native PDH-bypass. The compositions and methods described herein provide an energy-efficient yet redox balanced route for the heterologous production of acetyl-CoA-derived isoprenoids.
    Type: Application
    Filed: September 2, 2014
    Publication date: April 2, 2015
    Applicant: AMYRIS, INC.
    Inventors: Timothy Stevens GARDNER, Kristy Michelle HAWKINS, Adam Leon MEADOWS, Annie Ening TSONG, Yoseph TSEGAYE
  • Patent number: 8993289
    Abstract: A biomass is used to prepare bio-acetone which is converted to bio-mesitylene in high chemical yield and selectivity and the latter is converted using continuous flow chemical processes to a variety of functionalized bioaromatics that are useful in the preparation of high performance biopolymers, biocomposites, bio-explosives, and bio-adhesives.
    Type: Grant
    Filed: February 19, 2013
    Date of Patent: March 31, 2015
    Assignee: The United States of America as Represented by the Secretary of the Navy
    Inventor: Michael E. Wright
  • Patent number: 8993282
    Abstract: The present invention provides a method for producing a carotenoid, which comprises culturing a carotenoid-producing bacterium in an amino acid-supplemented medium, and collecting the carotenoid from the resulting cultured product, wherein the amino acid is at least one selected, from the group consisting of glutamic acid, aspartic acid, glutamine, asparagine, alanine, glycine, serine, threonine, arginine, tyrosine, proline, phenylalanine and leucine, and salts thereof.
    Type: Grant
    Filed: October 16, 2009
    Date of Patent: March 31, 2015
    Assignee: JX Nippon Oil & Energy Corporation
    Inventors: Kazuaki Hirasawa, Akira Tsubokura, Hiroshi Satou, Tetsuhisa Yata
  • Patent number: 8993262
    Abstract: The present invention provides methods for catalyzing the conversion of an olefin to any compound containing one or more cyclopropane functional groups using heme enzymes. In certain aspects, the present invention provides a method for producing a cyclopropanation product comprising providing an olefinic substrate, a diazo reagent, and a heme enzyme; and admixing the components in a reaction for a time sufficient to produce a cyclopropanation product. In other aspects, the present invention provides heme enzymes including variants and fragments thereof that are capable of carrying out in vivo and in vitro olefin cyclopropanation reactions. Expression vectors and host cells expressing the heme enzymes are also provided by the present invention.
    Type: Grant
    Filed: February 20, 2014
    Date of Patent: March 31, 2015
    Assignee: California Institute of Technology
    Inventors: Pedro S. Coelho, Eric M. Brustad, Frances H. Arnold, Zhan Wang, Jared C. Lewis
  • Publication number: 20150087042
    Abstract: The present invention provides genetically modified eukaryotic host cells that produce isoprenoid precursors or isoprenoid compounds. A subject genetically modified host cell comprises increased activity levels of one or more of mevalonate pathway enzymes, increased levels of prenyltransferase activity, and decreased levels of squalene synthase activity. Methods are provided for the production of an isoprenoid compound or an isoprenoid precursor in a subject genetically modified eukaryotic host cell. The methods generally involve culturing a subject genetically modified host cell under conditions that promote production of high levels of an isoprenoid or isoprenoid precursor compound.
    Type: Application
    Filed: August 4, 2014
    Publication date: March 26, 2015
    Inventors: Jay D. Keasling, James Kirby, Eric M. Paradise
  • Patent number: 8986965
    Abstract: The present invention relates to methods for producing monoterpenes, particularly tricyclene, by culturing microbial organisms that express a terpene synthase and optionally a prenyl transferase.
    Type: Grant
    Filed: March 30, 2011
    Date of Patent: March 24, 2015
    Assignee: Codexis, Inc.
    Inventors: Robert McDaniel, Galit Meshulam-Simon, Oscar Alvizo, Xiyun Zhang
  • Patent number: 8986948
    Abstract: The present invention relates to the use of nucleic acid molecules coding for a bacterial xylose isomerase (XI), preferably coming from Clostridium phytofermentans, for reaction/metabolization, particularly fermentation, of recombinant microorganisms of biomaterial containing xylose, and particularly for the production of bioalcohols, particularly bioethanol, by means of xylose fermenting yeasts. The present invention further relates to cells, particularly eukaryotic cells, which are transformed utilizing a nucleic acid expression construct which codes for a xylose isomerase, wherein the expression of the nucleic acid expression construct imparts to the cells the capability to directly isomerize xylose into xylulose. Said cells are preferably utilized for reaction/metabolization, particularly fermentation, of biomaterial containing xylose, and particularly for the production of bioalcohols, particularly bioethanol.
    Type: Grant
    Filed: July 1, 2009
    Date of Patent: March 24, 2015
    Assignee: Lesaffre et Compagnie
    Inventors: Dawid Brat, Eckhard Boles, Marco Keller, Beate Wiedemann
  • Publication number: 20150082493
    Abstract: The present invention relates to GH61 polypeptide variants. The present invention also relates to polynucleotides encoding the variants; nucleic acid constructs, vectors, and host cells comprising the polynucleotides; and methods of using the variants.
    Type: Application
    Filed: April 26, 2013
    Publication date: March 19, 2015
    Inventors: Janine Lin, Doreen Bohan, Michelle Maranta, Leslie Beresford, Michael Lamsa, Matt Sweeney, Mark Wogulis, Elizabeth Znameroski, Frank Winther Rasmussen
  • Publication number: 20150079646
    Abstract: The present invention relates to yeast cells producing high levels of acetoacetyl-CoA. It also relates to a method for making such yeast cells and to the use of such yeast cells in a method for producing acetyl-CoA derived products.
    Type: Application
    Filed: December 17, 2012
    Publication date: March 19, 2015
    Applicant: FIRMENICH SA
    Inventors: Jens Nielsen, Verena Siewers, Yun Chen, Laurent Daviet, Michel Schalk
  • Patent number: 8980620
    Abstract: The present invention relates to the use of microorganisms (biocatalysts), or catalysts derived from these organisms (enzymes), to improve the quality of crude oil and bitumen as an attractive alternative to current upgrading methods. The invention identifies and characterizes the microorganism species, in particular, N. muscorum (UTEX 2209) and Kocuria rhizophilia (ATCC533), that have the capability to biochemically convert organic acids into chemical species that do not possess corrosive properties.
    Type: Grant
    Filed: April 24, 2009
    Date of Patent: March 17, 2015
    Assignee: Her Majesty the Queen in Right of Canada as Represented by the Minister of Natural Resources
    Inventors: Heather D. Dettman, Ryan Lister, Louis D. Heerze
  • Patent number: 8980578
    Abstract: The present invention provides fungal xylanase and/or beta-xylosidase enzymes suitable for use in saccharification reactions. The present application further provides genetically modified fungal organisms that produce xylanase and/or beta-xylosidases, as well as enzyme mixtures exhibiting enhanced hydrolysis of cellulosic material to fermentable sugars, enzyme mixtures produced by the genetically modified fungal organisms, and methods for producing fermentable sugars from cellulose using such enzyme mixtures.
    Type: Grant
    Filed: June 10, 2013
    Date of Patent: March 17, 2015
    Assignee: Codexis, Inc.
    Inventors: Ryan Fong, Xiyun Zhang, Chris Noriega, Nicholas Agard, Anupam Gohel, Derek Smith
  • Patent number: 8969030
    Abstract: The present invention refers to a process to produce biodiesel and/or fuel oil from microbial oilseed and/or algal biomass and/or from sugar cane residues and derivatives. The products according to the present invention are appropriate for direct use in motors and to generate energy or steam. The integrated process of the present invention comprises the use, as raw materials, of microbial oil-producing biomass obtained from sugar cane residues and derivatives, which is integrated with algal biomass and/or glycerol and are processed by steps of production of oil-producing microbial biomass from filamentous fungi and/or yeasts, steps of simultaneous production of algal biomass by fully using residues, CO2 and residual broth of said production of microbial biomass, as well as steps of extraction and transesterification of lipids contained in the biomass, with reuse of the residual glycerol thus produced.
    Type: Grant
    Filed: May 2, 2008
    Date of Patent: March 3, 2015
    Assignee: Ouro Fino Participacoes e Empreendimentos Ltda
    Inventor: Dolivar Coraucci Neto
  • Patent number: 8956833
    Abstract: Genetically manipulated cells, lysates of such cells, systems, and methods of use thereof are provided, where one or more enzymes in a pathway of interest are genetically modified to incorporate a peptide sequence that provides for relocation of the protein, e.g., to the periplasm, so as to sequester the enzyme, and where the enzyme controls flux in the pathway of interest.
    Type: Grant
    Filed: May 6, 2011
    Date of Patent: February 17, 2015
    Assignees: GreenLight Biosciences, Inc., The Board of Trustees of the Leland Stanford Junior University
    Inventor: James R. Swartz
  • Patent number: 8951764
    Abstract: Embodiments of the present disclosure relate to a process for producing isoprenoid precursor molecules and/or isoprenoids from a starch substrate by saccharification and/or fermentation. The saccharification is effectively catalyzed by a glucoamylase at a pH in the range of 5.0 to 8.0. At a pH of 6.0 or above, the glucoamylase possesses at least 50% activity relative to its maximum activity. The saccharification and fermentation may be performed as a simultaneous saccharification and fermentation (SSF) process.
    Type: Grant
    Filed: August 3, 2012
    Date of Patent: February 10, 2015
    Assignee: Danisco US Inc.
    Inventors: Martien H. Bergsma, Anthony R. Calabria, Gopal K. Chotani, William A. Cuevas, Gang Duan, Sung Ho Lee, Ying Qian, Vivek Sharma, Jayarama K. Shetty, Bruce A. Strohm, Paula Johanna Maria Teunissen, Hongxian Xu
  • Publication number: 20150031077
    Abstract: The efficient production of ethanol from low-cost biomass (e.g., corn, sugar beets, sugar cane, switchgrass and/or paper) has become increasingly important in making ethanol competitive with gasoline and decreasing the United States' dependence on foreign oil. For example, to reduce the cost of transporting biomass to ethanol production facilities, mobile systems for producing ethanol from biomass are provided. Also provided are small-scale ethanol production facilities. For example, instead of transporting biomass to the production facility, the facility is transported to the biomass or is located nearby the source of the biomass. The ethanol production facilities or components thereof may be transported via land, water, or air. Production of other products, such as hydrocarbons, natural gas, hydrogen gas, plastics, polymers, and proteins, can also be made by the methods and facilities. Any product described herein can be made in finished form or un-finished form and moved, e.g., to a fixed facility, e.g.
    Type: Application
    Filed: September 9, 2014
    Publication date: January 29, 2015
    Inventor: Marshall Medoff
  • Publication number: 20150031079
    Abstract: The present invention relates to isolated polypeptides having xylanase activity and polynucleotides encoding the polypeptides. The invention also relates to nucleic acid constructs, vectors, and host cells comprising the polynucleotides as well as methods of producing and using the polypeptides.
    Type: Application
    Filed: October 13, 2014
    Publication date: January 29, 2015
    Inventor: Nikolaj Spodsberg