Staphylococcus Patents (Class 435/882)
  • Patent number: 4335211
    Abstract: Disclosed are optically active acylated cephalosporin analogs which are useful as antibacterial agents and methods for preparing such compounds.
    Type: Grant
    Filed: November 13, 1980
    Date of Patent: June 15, 1982
    Assignee: Kyowa Hakko Kogyo Co., Ltd.
    Inventors: Yukio Hashimoto, Seigo Takasawa, Tadashi Hirata, Ikuo Matsukuma, Shigeo Yoshiie
  • Patent number: 4302540
    Abstract: Disclosed are optically active cephalosporin analogs which are produced by optically selective deacylation of an optically inactive acylated analog. The compounds are useful as intermediates in the preparation of optically active acylated antimicrobial agents.
    Type: Grant
    Filed: October 24, 1980
    Date of Patent: November 24, 1981
    Assignee: Kyowa Hakko Kogyo Co., Ltd.
    Inventors: Tadashi Hirata, Yukio Hashimoto, Takehiro Ogasa, Shigeru Kobayashi, Akira Sato, Kiyoshi Sato, Seigo Takasawa
  • Patent number: 4302541
    Abstract: Optically active cephalosporin analogs are produced by optically selective deacylation of an optically inactive acylated analog. The compounds are useful as intermediates in the preparation of optically active acylated antimicrobial agents.
    Type: Grant
    Filed: November 13, 1980
    Date of Patent: November 24, 1981
    Assignee: Kyowa Hakko Kogyo Co., Ltd.
    Inventors: Tadashi Hirata, Yukio Hashimoto, Ikuo Matsukuma, Shigeo Yoshiie, Seigo Takasawa
  • Patent number: 4268434
    Abstract: Extracellular products of oral bacteria have been isolated and have been found to have immunosuppressive activity. Genus Streptococcus and genus Actinomyces are preferred, particularly Streptococcus mutans, Streptococcus intermedius, Streptococcus salivarius, Actinomyces viscosus and Actinomyces naeslundii.
    Type: Grant
    Filed: January 9, 1979
    Date of Patent: May 19, 1981
    Inventors: Thomas B. Higerd, Jean-Michel C. Goust
  • Patent number: 4259442
    Abstract: Rapid identification of different species of Streptococcus is accomplished by: culturing the bacteria for several hours under unusual conditions which induces the bacteria to create characteristic enzymes by which the bacteria can be identified, and in a medium containing no more than about 1 g of glucose per liter of culture medium to produce a dense culture; distributing the culture onto several supports containing different substrates which are capable of reacting with enzymes so produced by different species of Streptococcus under the unusual conditions; and incubating the culture to produce a distinctly colored or colorable reaction product.
    Type: Grant
    Filed: September 26, 1978
    Date of Patent: March 31, 1981
    Assignee: Laboratoire de Recherche Api S.A.R.L.
    Inventor: Jean-Pierre Gayral