Abstract: The present invention includes a novel yeast strain of the genus Saccharomyces boulardii sequela PY31 ATCC 74366 that is able to process certain metallic compounds into biologically active forms suitable for supplementing the human diet. The present invention also includes methods for isolating such yeast, nutritional supplement compositions containing such yeast, and methods of administering the nutritional supplement compositions to humans.

Abstract: A microbial process for converting codeine to 14-hydroxycodeine is provided. This process comprises aerobically culturing codeine with bacteria of the genus Streptomyces for at least about 3 days in a rich medium such as soybean flour medium.

Abstract: A method of increasing the yield of a desired product, such as an antibiotic, by an organism which normally must first become inducibly resistant to that product before it can produce the product in maximum yields comprises producing constitutively resistant cells of the organism by supplementing a culture of the organism with an agent in which only cells able to specifically modify the 23S ribosomal RNA constitutively, rather than inducibly, survive thereby producing an organism in which the resistance to the product is expressed without the need for activation by the induction process; followed by purification and utilization of that organism for increased product production.