Streptosporangium Patents (Class 435/907)
  • Analyte assays and devices
    Patent number: 6235539
    Abstract: The present invention provides a method and a device that utilizes capillarity-mediated, chromatographic transport, for the qualitative or semi-quantitative analysis of selected analytes in liquid samples. The device utilizes an applicator/collection device for collecting and administering the sample to the flow path such that reagent(s) flow through the applicator/collection device, washing the sample into the reaction pathway. The device farther utilizes an air gap between the initial location of the reagent and the reaction pathway to funnel the reagent efficiently through the sample so as to collect all or substantially all of the sample and make it available for the reaction(s).
    Type: Grant
    Filed: June 26, 1998
    Date of Patent: May 22, 2001
    Assignee: IDEXX Laboratories, Inc.
    Inventor: Charles Carpenter
  • Process for producing optically active amino acids
    Patent number: 5081024
    Abstract: An efficient process of optical resolution is provided for producing an L-amino acid represented by the following formula (I): ##STR1## wherein R is --CH.sub.2 CO.sub.2 H, --CH.sub.2 CONH.sub.2, --CO.sub.2 H or ##STR2## in which R.sup.1 is hydrogen atom, an alkyl group having 1 to 10 carbon atoms or a halogen-substituted alkyl group having 1 to 10 carbon atoms. The process comprises an optical resolution of an N-substituted carbonyl-D,L-amino acid represented by the formula (II): ##STR3## (wherein R is the same as defined above and R.sup.
    Type: Grant
    Filed: August 22, 1989
    Date of Patent: January 14, 1992
    Assignee: Nissan Chemical Industries, Ltd.
    Inventors: Masao Kuwahara, Michito Tagawa, Takashi Furusato, Hiroyuki Narushima, Shuzo Shinke
  • Novel proteinous substance KUD-PC and its production
    Patent number: 4529542
    Abstract: A novel proteinous substance KUP-PC, which is produced by culturing proteinous substance KUD-PC producing organisms belonging to the genus Streptosporangium. KUD-PC increases the antitumor activity of the anti-tumor substance, sporamycin.
    Type: Grant
    Filed: June 21, 1983
    Date of Patent: July 16, 1985
    Assignee: The Kitasato Institute
    Inventors: Iwao Umezawa, Kanki Komiyama
  • Anthracycline antibiotics produced by streptosporangium fragile
    Patent number: 4385122
    Abstract: A novel anthracycline antibiotic complex, fragilomycin complex, is produced by the cultivation of a fermentation broth containing Streptosporangium fragile Shearer sp. nov. ATCC 31519 microorganisms in an aqueous nutrient medium under submerged aerobic conditions. The fragilomycin complex and its major bioactive component, fragilomycin A, exhibit antibiotic activity.
    Type: Grant
    Filed: August 21, 1981
    Date of Patent: May 24, 1983
    Assignee: SmithKline Beckman Corporation
    Inventors: Claude H. Nash, III, Marcia C. Shearer, Kenneth M. Snader, Joseph R. Valenta, David Cooper
  • Antibiotic compound
    Patent number: 4162938
    Abstract: A novel anthracycline antibiotic designated rudolphomycin is produced by fermentaion of Actinosporangium sp. ATCC 31127 and isolation of the new antibiotic free of substances co-produced therewith. Rudolphomycin and its pharmaceutically acceptable salts exhibit antimicrobial activity and inhibit the growth of mammalian tumors.
    Type: Grant
    Filed: May 30, 1978
    Date of Patent: July 31, 1979
    Assignee: Bristol-Myers Company
    Inventors: Donald E. Nettleton, Jr., Terrence W. Doyle, William T. Bradner