Oxides Of Nitrogen Patents (Class 436/116)
  • Patent number: 11649263
    Abstract: Some embodiments described herein relate to a method that includes separating an analyte-containing sample via electrophoresis in a capillary. The capillary is loaded with a chemiluminescence agent, such as luminol, that is configured to react with the analyte (e.g., HRP-conjugated proteins) to produce a signal indicative of a concentration and/or quantity of analyte at each location along the length of the capillary. A first image of the capillary containing the analytes and the chemiluminescence agent is captured over a first period of time. A second image of the capillary containing the analytes and the chemiluminescence agent is captured over a second, longer, period of time. A concentration and/or quantity of a first population of analytes at a first location is determined using the first image, and a concentration and/or quantity of a second population of analytes at a second location is determined using the second image.
    Type: Grant
    Filed: May 28, 2019
    Date of Patent: May 16, 2023
    Assignee: ProteinSimple
    Inventors: Hui Xu, Kenneth Swartz
  • Patent number: 11300552
    Abstract: A measurement system is disclosed that includes features for detecting the presence of nitric oxide from a gas sample, such as exhaled breath. The measurement system includes an assembly that introduces one or more reducing gases into a reactor-sensor assembly to help stabilize the sensor signal response and improve the performance of the assembly over time. Suitable reducing gases include hydrogen gas (H2), carbon dioxide (CO), benzaldehyde, bisphenol A, and other similar compounds. The reducing gas may be introduced directly from one or more surrounding gases or through tubing or inline piping. The reducing gas may be generated from the liquid or solid forms.
    Type: Grant
    Filed: February 28, 2018
    Date of Patent: April 12, 2022
    Assignees: CAIRE Diagnostics Inc., NGK Spark Plug Co., Ltd.
    Inventors: Takahiro Yokoyama, Tatsunori Ito, Hiroyuki Nishiyama, Masahiro Takakura, Shigeya Aoyama, Ryan R. Leard, David Anvar, Solomon Ssenyange
  • Patent number: 11125134
    Abstract: Briefly, in one aspect, a catalytic assembly described herein comprises a module comprising at least one layer of structural catalyst bodies having an inlet face for receiving a gas stream. A diffuser assembly is arranged a distance of greater than 50 mm from the inlet face, the diffuser assembly including at least one diffuser element comprising a plurality of apertures, wherein a ratio of aperture length (L) in the gas stream flow direction to aperture hydraulic diameter (Da) is less than 1.
    Type: Grant
    Filed: June 22, 2020
    Date of Patent: September 21, 2021
    Assignee: CORMETECH, INC.
    Inventors: Mark L Schirmer, Christian Trefzger, Stephen M Lyons, Colby A Burtt, William D Buynitzky, Chris E Difrancesco
  • Patent number: 11002741
    Abstract: A single chirality single walled carbon nanotubes (SWNT), and combinations thereof, can be used to detect trace levels of chemical compounds in vivo with high selectivity.
    Type: Grant
    Filed: September 18, 2015
    Date of Patent: May 11, 2021
    Assignee: MASSACHUSETTS INSTITUTE OF TECHNOLOGY
    Inventors: Juan Pablo Giraldo Gomez, Markita Patricia Landry, Michael S. Strano
  • Patent number: 10871443
    Abstract: A gas analyzer includes an oxidation device and a subsequent photometer, wherein the oxidation device has a reaction chamber located in an exhaust gas path and a heating chamber downstream thereof, where an ultraviolet light source generates ozone from residual oxygen content of the exhaust gas within the reaction chamber to convert nitrogen monoxide into nitrogen dioxide in the exhaust gas, nitrogen oxides and excess ozone are broken down into nitrogen dioxide and oxygen in the heating chamber, the photometer outputs the measured nitrogen dioxide concentration as nitrogen oxide concentration of the untreated exhaust gas, and where an additional photometer is located in the exhaust gas path between the reaction chamber and the heating chamber which, via light absorption, measures the ozone concentration in the partially treated exhaust gas and outputs the same as oxygen concentration of the untreated exhaust gas.
    Type: Grant
    Filed: July 16, 2018
    Date of Patent: December 22, 2020
    Assignee: Siemens Aktiengesellschaft
    Inventors: Camiel Heffels, Benjamin Schmidt
  • Patent number: 10761018
    Abstract: A system and method for determining impurities in a beverage grade gas such as CO2 or N2 relies on a coupling of FTIR analysis and UV fluorescence detection. Conversion of reduced sulphur present in some impurities to SO2 can be conducted using a furnace. In some cases, CO2% also is determined.
    Type: Grant
    Filed: July 25, 2019
    Date of Patent: September 1, 2020
    Assignee: MLS ACQ, INC.
    Inventors: Martin L. Spartz, Peter Paul Behnke, Charles Mark Phillips, Adam R. Klempner, Anthony S. Bonanno
  • Patent number: 10690035
    Abstract: Briefly, in one aspect, a catalytic assembly described herein comprises a module comprising at least one layer of structural catalyst bodies having an inlet face for receiving a gas stream. A diffuser assembly is arranged a distance of greater than 50 mm from the inlet face, the diffuser assembly including at least one diffuser element comprising a plurality of apertures, wherein a ratio of aperture length (L) in the gas stream flow direction to aperture hydraulic diameter (Da) is less than 1.
    Type: Grant
    Filed: February 15, 2019
    Date of Patent: June 23, 2020
    Assignee: Cormetech, Inc.
    Inventors: Mark L. Schirmer, Christian Trefzger, Steve M. Lyons, Colby A. Burtt, William D. Buynitzky, Chris E. Difrancesco
  • Patent number: 9498656
    Abstract: A self-contained breathing device for use in fighting fires comprising a hood for covering a wearer's head, a membrane for sealing the hood to create a breathing chamber inside the hood, and a source of oxygen disposed inside the hood. The source of oxygen is connected to the user by a conduit inside of the hood, and another conduit directs user-exhaled carbon dioxide to the source of oxygen. The breathing device includes a visual indicator inside of the hood that reacts to the presence of a gas within the hood and provides visual feedback to the user based on a quantity of the gas present in the hood.
    Type: Grant
    Filed: July 11, 2012
    Date of Patent: November 22, 2016
    Assignee: B/E AEROSPACE, INC.
    Inventors: Andrew Elliott, Girish Kshirsager, Wayne Noehren, Chip Kuper
  • Patent number: 9316623
    Abstract: A passive and reusable preconcentrator/injector device for measuring gas-phase analytes and methods of use. The device includes an upper plate defining an array of micro-scale diffusion channels and a lower plate secured to the upper plate. The lower plate defines a cavity for a reusable collection material in fluid communication with the micro-scale diffusion channels. An integral heating unit is provided adjacent the lower plate and configured for heating the cavity. A loading port may be included for introducing the reusable collection material into the cavity. An inlet port and an outlet port are provided, both in fluid communication with the cavity. The device may include a fluidic manifold system comprising a plurality of conduits disposed between the adsorbent cavity and the outlet port.
    Type: Grant
    Filed: January 22, 2013
    Date of Patent: April 19, 2016
    Assignee: The Regents Of The University Of Michigan
    Inventors: Jung Hwan Seo, Sun Kyu Kim, Edward T. Zellers, Katsuo Kurabayashi
  • Patent number: 8999722
    Abstract: Sensors and methods for determination of analytes are provided. Analytes including explosives (e.g., RDX or PETN) may be determined by monitoring, for example, a change in an optical signal of a material upon exposure to the analyte. In some embodiments, the analyte and the material may interact via a chemical reaction to form a new emissive species. Embodiments described herein may provide inexpensive sensors with high selectivity and sensitivity.
    Type: Grant
    Filed: March 30, 2012
    Date of Patent: April 7, 2015
    Assignee: Massachusetts Institute of Technology
    Inventors: Timothy M. Swager, Trisha L. Andrew
  • Patent number: 8980640
    Abstract: The present invention relates to gas sensors using doped ferroelectric materials. The sensors can be fabricated as an array where different portions of the array can operate at different independently controlled temperatures to detect different gas phase components of a gas sample. Preferred embodiments can be used for the diagnosis of conditions, such as, diabetes.
    Type: Grant
    Filed: December 2, 2010
    Date of Patent: March 17, 2015
    Assignee: The Research Foundation of State University of New York
    Inventor: Pelagia-Irene Gouma
  • Patent number: 8975014
    Abstract: The invention herein disclosed provides for compositions, methods for synthesizing said compositions, and methods for using said compositions, wherein the compositions and methods may be used to bind to and/or deactivate a poison oak oil, such as urushiol. The compositions and methods can be used to treat and/or reduce an inflammatory reaction and/or hypersensitivity to natural compounds found in poison oak, poison ivy, poison sumac, mango, lac tree, and cashew nut.
    Type: Grant
    Filed: May 6, 2014
    Date of Patent: March 10, 2015
    Assignee: The Regents of the University of California
    Inventor: Rebecca Braslau
  • Patent number: 8932873
    Abstract: A method for monitoring the concentration of water borne substances in an aqueous medium, by introducing a defined amount of the aqueous medium into a gas circulatory system of an analytical apparatus which extends through a high temperature reaction chamber and a measuring chamber. The introducing of the aqueous medium occurs upstream of the high temperature reaction chamber or into it. The aqueous medium is evaporated in the high temperature reaction chamber, the water borne substance with at least one reaction partner in the high temperature reaction chamber reacts to a gaseous reaction product, and a current value of a measured variable is registered, which is a function of the concentration of the chemical species of the reaction product in the gas circulatory system.
    Type: Grant
    Filed: November 30, 2007
    Date of Patent: January 13, 2015
    Assignee: Endress + Hauser Conducta Gesellschaft fur Mess- und Regeltechnik mBH + Co. KG
    Inventors: Ulrich Kathe, Thomas Schipolowski, Oliver Bettmann, Björn Emling
  • Patent number: 8906693
    Abstract: The subject invention presides novel devices and methods for the measurement of nitric oxide in biological samples, including wound fluid samples. These advantageous devices and methods can be used for clinicians to monitor the wound's nitric oxide metabolism and/or response to treatment.
    Type: Grant
    Filed: June 3, 2010
    Date of Patent: December 9, 2014
    Assignee: University of Florida Research Foundation, Inc.
    Inventors: Gregory S. Schultz, Daniel J. Gibson
  • Publication number: 20140350097
    Abstract: There is provided a method for the prevention and/or treatment of hypotension associated with hemodialysis, which method includes administering to a subject in need thereof an effective amount of at least one physiologically compatible compound which, in combination with iron, binds nitric oxide. There is further provided a method for identifying hemodialysis subjects for whom treatment with an effective amount of at least one physiologically compatible compound which, in combination with iron, binds nitric oxide is indicated. The method includes monitoring the subject's nitric oxide levels, and selecting those subjects having elevated nitric oxide levels for treatment with an effective amount of at least one physiologically compatible compound which, in combination with iron, binds nitric oxide, wherein the effective amount is sufficient to maintain the subject's nitric oxide levels within an acceptable range.
    Type: Application
    Filed: May 23, 2013
    Publication date: November 27, 2014
    Applicant: Medinox,Inc.
    Inventor: Ching-San Lai
  • Patent number: 8895319
    Abstract: The present invention provides a nanohybrid type nitrogen monoxide detecting sensor and a production method therefor in which the nanohybrid type nitrogen monoxide detecting sensor includes a fluorescent semiconducting quantum dot and a transition metal compound. Employing a nanohybrid structure including semiconducting quantum dot nano-particles combined with a molecule recognizer selectively forming a bonding to nitrogen monoxide, the nitrogen monoxide detecting sensor is enabled to detect an infinitesimal amount of nitrogen monoxide by bringing about photoluminescence upon detection of nitrogen monoxide.
    Type: Grant
    Filed: March 16, 2010
    Date of Patent: November 25, 2014
    Assignee: Korea Institute of Ceramic Engineering and Technology
    Inventors: Eunhae Koo, Sung-ho Yoon, Jong-chul Lee, Jong-hee Kim
  • Patent number: 8895317
    Abstract: A compound represented by the general formula (I) [R1 and R2 are amino groups that substitute at adjacent positions on the benzene ring; R3 and R4 are halogen atoms; R5 and R6 represent hydrogen atom, an acyl group or an acyloxy(C1-6 alkyl) group; R7 and R8 represent —(CH2)p—N(R9)(R10) (p is 1 to 4, and R9 and R10 represent —(CH2)n—COOH (n is 1 to 4))], which is useful for measuring a reactive nitrogen species existing in cells such as nitrogen monoxide or peroxynitrite at high sensitivity over a long period of time.
    Type: Grant
    Filed: December 4, 2009
    Date of Patent: November 25, 2014
    Assignee: The University of Tokyo
    Inventors: Tetsuo Nagano, Yasuteru Urano, Saki Izumi
  • Patent number: 8852950
    Abstract: A method for determining an NOx concentration in a measurement gas is provided, where a measurement value for the NOx concentration is determined from the sensor signal of a gas sensor and a measurement value for the concentration of a second component in the measurement gas is determined. A corrected value for the NOx in the measurement gas is determined from the measurement values, and the measurement value and the corrected measurement value for the NOx concentration are displayed and/or output.
    Type: Grant
    Filed: September 3, 2008
    Date of Patent: October 7, 2014
    Assignee: Testo AG
    Inventors: Knut Hoyer, Andreas Kaufmann, Reinhold Munch, Thomas Springmann
  • Patent number: 8846407
    Abstract: A method and device for detecting explosive compounds in an air sample in which the air sample is filtered with activated carbon treated with a weakly basic solution, after which the air sample is divided into two parts, with one part being heated at lower temperatures to decompose non-explosive nitrogenous compounds and the second part being heated at higher temperatures to decompose explosive nitrogenous compounds. Nitrogen dioxide is measured in both portions of the air sample with a spectrographic detector, and the presence or absence of explosive nitrogenous compounds in the air sample is determined.
    Type: Grant
    Filed: June 15, 2012
    Date of Patent: September 30, 2014
    Inventor: James M. Hargrove
  • Publication number: 20140287514
    Abstract: The present invention includes a sensing device and method detecting the presence of a chemical analyte, comprising: a surface; a continuous or discontinuous terbium(III)-triphenylphosphine oxide coordination polymer layer deposited on the surface, wherein the polymer layer is porous; and a luminescence detector, wherein one or more analytes that interact with the polymer layer luminesce at distinct wavelengths unique to each analyte.
    Type: Application
    Filed: March 17, 2014
    Publication date: September 25, 2014
    Inventors: Simon M. Humphrey, Bradley J. Holliday
  • Publication number: 20140273258
    Abstract: A functional element positioned in front of an active detection region of a sensor element has a compact main body with a gas-side surface, a sensor-side surface, and at least two functional channels located between the gas-side surface and the sensor-side surface. The functional channels have a functionality that is different from one another with respect to a gas that can pass through. Such a functional element allows particularly variable operation of a sensor with great long-term stability.
    Type: Application
    Filed: March 5, 2014
    Publication date: September 18, 2014
    Applicant: Robert Bosch GmbH
    Inventors: Richard Fix, Andreas Krauss
  • Patent number: 8828734
    Abstract: Provided are a nitric oxide detection element capable of detecting NO gas contained in a mixed gas at a high speed even when the amount thereof is a super trace amount of ten and several parts per billion; and a process for producing the element. In a nitric oxide detection element having a substrate 12 and a sensing film 11 formed on a surface of the substrate, the sensing film is composed of nitric oxide sensing particles and a polymer adhesive. The nitric oxide sensing particles are produced by adsorbing a dye having a porphyrin skeleton and having, as a central metal, divalent cobalt onto surfaces of inorganic particles.
    Type: Grant
    Filed: July 12, 2011
    Date of Patent: September 9, 2014
    Assignees: Panasonic Healthcare Co., Ltd., National University Corporation Ehime University
    Inventors: Kouichi Hiranaka, Toyofumi Nagamatsu, Yoshihiko Sadaoka, Yoshiteru Itagaki
  • Publication number: 20140227368
    Abstract: The present invention includes a method for scavenging nitric oxide. The method includes contacting the nitric oxide with cerium oxide nanoparticles having a low 3+/4+ ratio.
    Type: Application
    Filed: February 14, 2013
    Publication date: August 14, 2014
    Applicant: University of Central Florida Research Foundation Inc.
    Inventors: William Self, Sudipta Seal, Janet Dowding
  • Patent number: 8796034
    Abstract: A handheld, small but accurate and reliable device for diagnostic NO measurements using a NO sensor, where the parameters governing the taking of the sample are different from the parameters optimal for the accuracy of said NO sensor. By temporarily storing a portion of the exhaled air, and feeding this to the sensor at a flow rate adapted to the NO sensor, the accuracy and sensitivity of a system/method involving NO sensors, in particular electrochemical NO sensors, can be increased. The method for diagnostic NO measurements comprises steps for controlling the inhalation of NO free air, as well as the exhalation, both by built-in means and by audible and/or visual feedback to the patient.
    Type: Grant
    Filed: October 31, 2013
    Date of Patent: August 5, 2014
    Assignee: Aerocrine AB
    Inventors: Pontus von Bahr, Tryggve Hemmingsson, Anders Jakobsson, Fredric Gustafsson
  • Publication number: 20140199771
    Abstract: An apparatus and method for measuring and controlling the NOx and ammonia slip content of a NOx-containing gas stream such as, for example, a combustion engine exhaust stream discharged from a Selective Catalytic Reduction (SCR) system. The apparatus includes an analyzer container which preferably has an ammonia slip catalyst element and a pair of automotive type NOx sensors positioned therein. One of the NOx sensors is positioned before and the other is positioned after the ammonia slip catalyst. The apparatus is heated by positioning the container in the gas stream and can draw a representative gas sample from any size conduit.
    Type: Application
    Filed: January 17, 2013
    Publication date: July 17, 2014
    Applicant: MIRATECH HOLDINGS, LLC
    Inventor: MIRATECH HOLDINGS, LLC
  • Publication number: 20140179014
    Abstract: Nitric oxide probes including a compound represented by Formula, I, II, III, IV, V, VI or a combination thereof are provided. Methods of using these nitric oxide probes to detect nitric oxide are also provided.
    Type: Application
    Filed: December 20, 2013
    Publication date: June 26, 2014
    Inventors: Eric V. Anslyn, Youjun Yang, Michelle M. Adams
  • Patent number: 8748187
    Abstract: A control system of a NOx removal device is provided with reagent introducing means for introducing a reagent into a fluid, a temperature measuring device that measures a temperature distribution of the fluid, a reagent-concentration calculating portion that calculates a concentration distribution of the reagent introduced into the fluid with the temperature distribution determined at the temperature measuring device, a reagent-flow-rate determining portion that determines a flow rate of the reagent that the reagent introducing means introduces in accordance with the concentration distribution calculated at the reagent-concentration calculating portion, and a reagent-introducing-means control portion that controls the reagent introducing means so as to introduce the reagent into the fluid at the flow rate determined at the reagent-flow-rate determining portion.
    Type: Grant
    Filed: January 6, 2011
    Date of Patent: June 10, 2014
    Assignee: Mitsubishi Heavy Industries, Ltd.
    Inventors: Taketoshi Yamaura, Yoshihiro Deguchi, Nobuyuki Ukai, Susumu Okino, Tatsuto Nagayasu
  • Publication number: 20140154811
    Abstract: Technologies are generally described for gas filtration and detection devices. Example devices may include a graphene membrane and a sensing device. The graphene membrane may be perforated with a plurality of discrete pores having a size-selective to enable one or more molecules to pass through the pores. A sensing device may be attached to a supporting permeable substrate and coupled with the graphene membrane. A fluid mixture including two or more molecules may be exposed to the graphene membrane. Molecules having a smaller diameter than the discrete pores may be directed through the graphene pores, and may be detected by the sensing device. Molecules having a larger size than the discrete pores may be prevented from crossing the graphene membrane. The sensing device may be configured to identify a presence of a selected molecule within the mixture without interference from contaminating factors.
    Type: Application
    Filed: November 30, 2012
    Publication date: June 5, 2014
    Inventors: Angele Sjong, Kraig Anderson, Gary L. Duerksen, Seth Adrian Miller
  • Patent number: 8735057
    Abstract: The invention herein disclosed provides for compositions, methods for synthesizing said compositions, and methods for using said compositions, wherein the compositions and methods may be used to bind to and/or deactivate a poison oak oil, such as urushiol. The compositions and methods can be used to treat and/or reduce an inflammatory reaction and/or hypersensitivity to natural compounds found in poison oak, poison ivy, poison sumac, mango, lac tree, and cashew nut.
    Type: Grant
    Filed: December 14, 2012
    Date of Patent: May 27, 2014
    Assignee: The Regents of the University of California
    Inventor: Rebecca Braslau
  • Publication number: 20140120574
    Abstract: Nitric oxide probes comprising a compound represented by Formula I are provided. Methods of using this nitric oxide probes to detect nitric oxide are also provided.
    Type: Application
    Filed: June 4, 2013
    Publication date: May 1, 2014
    Inventors: Eric V. Anslyn, Youjun Yang, Michelle A. Ivy
  • Patent number: 8685740
    Abstract: The present invention provides a method of determining the susceptibility of a subject to treatment with a leukotriene modifier by determining the subject's cysteinyl leukotriene (CysLT) level and the subject's level of eosinophilic airway inflammation and identifying a subject with a high ratio of CysLT levels to eosinophilic airway inflammation as susceptible to treatment with the leukotriene modifier. Also discussed is a method of treatment of subjects who are susceptible to treatment that includes administering a leukotriene modifier to such a subject.
    Type: Grant
    Filed: March 16, 2009
    Date of Patent: April 1, 2014
    Assignee: National Jewish Health
    Inventors: Nathan Rabinovitch, Erwin Gelfand
  • Publication number: 20140080122
    Abstract: Systems and methods related to optical nanosensors comprising photoluminescent nanostructures are generally described. Generally, the nanosensors comprise a photoluminescent nanostructure and a polymer that interacts with the photoluminescent nanostructure. In some cases, the interaction between the polymer and the nanostructure can be non-covalent (e.g., via van der Waals interactions). The nanosensors comprising a polymer and a photoluminescent nanostructure may be particularly useful in determining the presence and/or concentration of relatively small molecules, in some embodiments. In addition, in some instances the nanosensors may be capable of determining relatively low concentrations of analytes, in some cases determining as little as a single molecule. In some embodiments, the interaction between the analyte and the nanosensor (e.g.
    Type: Application
    Filed: July 15, 2013
    Publication date: March 20, 2014
    Applicant: Massachusetts Institute of Technology
    Inventors: Michael S. Strano, Jong-Ho Kim, Jinqing Zhang, Daniel A. Heller
  • Publication number: 20140065606
    Abstract: A single device to collect, transfer, and measure salivary nitric oxide analyte and metabolite, nitrite, a biomarker for nitric oxide, as well as, a method to assess the effects of diet and exercise on changing an individual's nitric oxide status and health.
    Type: Application
    Filed: September 6, 2013
    Publication date: March 6, 2014
    Applicant: Berkeley Test, LLC
    Inventors: Natalie Green, Juliana Green
  • Patent number: 8637323
    Abstract: Nitric oxide probes including a compound represented by Formula, I, II, III, IV, V, VI or a combination thereof are provided. Methods of using these nitric oxide probes to detect nitric oxide are also provided.
    Type: Grant
    Filed: October 4, 2012
    Date of Patent: January 28, 2014
    Assignee: Board of Regents, The University of Texas System
    Inventors: Eric V. Anslyn, Youjun Yang, Michelle M. Adams
  • Patent number: 8621911
    Abstract: A method and system for measuring or assessing the homeostatic relationship between gases in the body, environment or water. The measured or assessed level of gases in the body, environment or air uses the interrelationships of the various components in order to establish guidelines for treating individuals, the environment or water.
    Type: Grant
    Filed: January 25, 2011
    Date of Patent: January 7, 2014
    Inventor: William J. McFaul
  • Patent number: 8617897
    Abstract: Methods and kits to detect and quantitate NOx compounds in a biological sample are provided. The methods include reacting a mixture that includes a nitrite compound and a chromogenic reagent to form a colored compound, contacting the mixture with a retention medium configured to retain the colored compound, and detecting the colored compound retained on the retention medium.
    Type: Grant
    Filed: August 3, 2010
    Date of Patent: December 31, 2013
    Assignee: 3M Innovative Properties Company
    Inventor: Vinod P. Menon
  • Patent number: 8609426
    Abstract: A system is disclosed that extracts bodily fluid to a reaction chamber for monitoring a substance or property of the patient fluid. In one embodiment, a pump is used to advance the sample of bodily fluid through a filter to produce a filtrate. Another pump advances filtrate into the reaction chamber, while another pump advances reactant into the reaction chamber. A sensor in communication with the reaction chamber determines a concentration of nitric oxide or one of its metabolic products. Methods are also disclosed.
    Type: Grant
    Filed: January 26, 2012
    Date of Patent: December 17, 2013
    Inventor: James H Silver
  • Patent number: 8597580
    Abstract: A handheld, small but accurate and reliable device for diagnostic NO measurements using a NO sensor, where the parameters governing the taking of the sample are different from the parameters optimal for the accuracy of said NO sensor I described. By temporarily storing a portion of the exhaled air, and feeding this to the sensor at a flow rate adapted to the NO sensor, the accuracy and sensitivity of a system/method involving NO sensors, in particular electrochemical NO sensors, can be increased. The method for diagnostic NO measurements comprises steps for controlling the inhalation of NO free air, as well as the exhalation, both by built-in means and by audible and/or visual feedback to the patient.
    Type: Grant
    Filed: November 16, 2010
    Date of Patent: December 3, 2013
    Assignee: Aerocrine AB
    Inventors: Pontus von Bahr, Tryggve Hemmingsson, Anders Jakobsson, Fredric Gustafsson
  • Publication number: 20130302903
    Abstract: Nitric oxide probes comprising a compound represented by Formula, I, II, III, IV, V, VI or a combination thereof are provided. Methods of using these nitric oxide probes to detect nitric oxide are also provided.
    Type: Application
    Filed: October 4, 2012
    Publication date: November 14, 2013
    Applicant: BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM
    Inventors: Eric V. Anslyn, Youjun Yang, Michelle M. Adams
  • Publication number: 20130280817
    Abstract: The invention relates to a multifunctional detector for gaseous compounds, or mixtures of gaseous compounds, selected from NH2Cl, NHCl2, NCl3, total chlorine, NOx, where x=1 or 2, O3, and X2, where X?Cl, Br, or I, in a sample, said detector including a first sensor including an iodide and a reactive compound selected from starch, amylose, amylopectin, xyloglucan, xylan, chitosan, glycogen, polyvinyl alcohol, cellulose or a cellulose compound, ?-cyclodextrin, theobromine, and polypropylene block polymers and polyethylene oxide block polymers, included in a block of sol-gel material that is absorbent in the UV spectrum but not in the visible spectrum. The invention also relates to the uses of said detector.
    Type: Application
    Filed: December 14, 2011
    Publication date: October 24, 2013
    Applicants: CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE - CNRS -, COMMISSARIAT A L'ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVES
    Inventors: Thu-Hoa Tran-Thi, Julien Garcia, Thi Dinh Nguyen, Trung-Hieu Nguyen
  • Patent number: 8563319
    Abstract: A nitrogen dioxide sensor comprising a first beam having a first functionalized sensing surface capable of sensing nitrogen dioxide, the first beam capable of producing a first resonant frequency; and a second beam having a second functionalized reference surface not capable of sensing nitrogen dioxide, the second beam capable of producing a second resonant frequency, wherein differential sensing of nitrogen dioxide may be performed, further wherein the first beam and the second beam are each functionalized with one or more soft bases having comparable viscoelastic properties is provided. In one embodiment, the sensor is a nano-sensor capable of low drift and accurate detection of nitrogen dioxide levels at the zeptogram level. Methods of making and using a nitrogen dioxide sensor are also provided.
    Type: Grant
    Filed: December 7, 2010
    Date of Patent: October 22, 2013
    Assignee: Honeywell Romania S.R.L.
    Inventors: Bogdan Catalin Serban, Cornel P. Cobianu, Mihai N. Mihaila, Viorel Georgel Dumitru, Octavian Buiu
  • Publication number: 20130224872
    Abstract: The present disclosure relates to a gas sensor, including: a gas collecting chamber including: (a) a nanoporous wall including alumina, on a portion of the gas collecting chamber in the near vicinity of the solid propellant fuel; a micro pump attached to the gas collecting chamber; and a gas analysis device connected to the gas collecting chamber. The gas analysis device measures both type and concentration of gases collected in the gas collecting chamber via the nanoporous wall, the gases measured being selected from the group consisting of CO, CO2, NO, N2O, NO2 and combinations thereof. The present disclosure also relates to a method of sensing propellant degradation in solid fuel and a method of using a gas collecting chamber to sense such degradation.
    Type: Application
    Filed: February 27, 2012
    Publication date: August 29, 2013
    Applicant: United States of America as represented by the Secretary of the Army
    Inventors: Christina L. Brantley, Eugene Edwards, Paul B. Ruffin, Fang Luo
  • Patent number: 8507288
    Abstract: The invention relates to the use of carbon nanomaterials as a filtration material pervious to nitrogen dioxide and impervious to ozone. The invention also relates to the use of carbon nanomaterials having a specific surface, measured by the BET method, of 15 to 40 m2/g inclusive and a form factor, equal to the ratio (highest dimension/lowest dimension) of the nanomaterial, of 5 to 250 inclusive, as material for filtering a gas mixture containing nitrogen dioxide and ozone, being pervious to the nitrogen dioxide and impervious to the ozone. The invention can be used in the field of air pollution.
    Type: Grant
    Filed: May 27, 2009
    Date of Patent: August 13, 2013
    Assignees: Centre National de la Recherche Scientifique, Universite Blaise Pascal—Clermont—Ferrand II
    Inventors: Alain Pauly, Marc Dubois, Katia Guerin, André Hamwi, Jérôme Brunet, Christelle Varenne, Bernard Lauron
  • Patent number: 8486709
    Abstract: Systems and methods related to optical nanosensors comprising photoluminescent nanostructures are generally described. Generally, the nanosensors comprise a photoluminescent nanostructure and a polymer that interacts with the photoluminescent nanostructure. In some cases, the interaction between the polymer and the nanostructure can be non-covalent (e.g., via van der Waals interactions). The nanosensors comprising a polymer and a photoluminescent nanostructure may be particularly useful in determining the presence and/or concentration of relatively small molecules, in some embodiments. In addition, in some instances the nanosensors may be capable of determining relatively low concentrations of analytes, in some cases determining as little as a single molecule. In some embodiments, the interaction between the analyte and the nanosensor (e.g.
    Type: Grant
    Filed: August 20, 2010
    Date of Patent: July 16, 2013
    Assignee: Massachusetts Institute ofTechnology
    Inventors: Michael S. Strano, Jong-Ho Kim, Jinqing Zhang, Daniel A. Heller
  • Publication number: 20130137184
    Abstract: Provided are a nitric oxide detection element capable of detecting NO gas contained in a mixed gas at a high speed even when the amount thereof is a super trace amount of ten and several parts per billion; and a process for producing the element. In a nitric oxide detection element having a substrate 12 and a sensing film 11 formed on a surface of the substrate, the sensing film is composed of nitric oxide sensing particles and a polymer adhesive. The nitric oxide sensing particles are produced by adsorbing a dye having a porphyrin skeleton and having, as a central metal, divalent cobalt onto surfaces of inorganic particles.
    Type: Application
    Filed: July 12, 2011
    Publication date: May 30, 2013
    Applicants: NATIONAL UNIVERSITY CORPORATION EHIME UNIVERSITY, PANASONIC HEALTHCARE CO., LTD.
    Inventors: Kouichi Hiranaka, Toyofumi Nagamatsu, Yoshihiko Sadaoka, Yoshiteru Itagaki
  • Patent number: 8440466
    Abstract: The nitrogen oxide analyzer obtains the ozone concentration-luminescence response characteristics that show the relationship between the ozone concentration and the light intensity by chemiluminescent response obtained by varying the ozone concentration alone in a steady state, and sets the relationship of the parameter that determines an average period of the sample gas passing the reactor so that the luminescence response is generated in the reactor alone even though the ozone concentration of the ozone-containing gas changes within a predetermined range based on the ozone concentration-luminescence response characteristics.
    Type: Grant
    Filed: April 4, 2006
    Date of Patent: May 14, 2013
    Assignee: Horiba, Ltd.
    Inventor: Hiroshi Nakamura
  • Publication number: 20130115706
    Abstract: The present invention relates to gas sensors using doped ferroelectric materials. The sensors can be fabricated as an array where different portions of the array can operate at different independently controlled temperatures to detect different gas phase components of a gas sample. Preferred embodiments can be used for the diagnosis of conditions, such as, diabetes.
    Type: Application
    Filed: December 2, 2010
    Publication date: May 9, 2013
    Inventor: Pelagia-Irene Gouma
  • Publication number: 20130065318
    Abstract: Sensors and methods for determination of analytes are provided. Analytes including explosives (e.g., RDX or PETN) may be determined by monitoring, for example, a change in an optical signal of a material upon exposure to the analyte. In some embodiments, the analyte and the material may interact via a chemical reaction to form a new emissive species. Embodiments described herein may provide inexpensive sensors with high selectivity and sensitivity.
    Type: Application
    Filed: March 30, 2012
    Publication date: March 14, 2013
    Applicant: Massachusetts Institute of Technology
    Inventors: Timothy M. Swager, Trisha L. Andrew
  • Patent number: 8372650
    Abstract: In a sensing element for a nitrogen oxide molecule of the present invention, a sensing portion that is to be bonded to a nitrogen oxide molecule to be sensed is fixed between paired metal electrodes through connecting portions. The sensing portion is a single porphyrin molecule or a single porphyrin derivative molecule each having, as a central metal thereof, iron or cobalt. The connecting portions are each a mercaptophenyleneethynyl group bonded to the single porphyrin molecule or the single porphyrin derivative molecule. Provided are a sensing element for nitrogen oxide molecule, a sensing apparatus for nitrogen oxide molecule, and a method for sensing nitrogen oxide molecule.
    Type: Grant
    Filed: March 28, 2012
    Date of Patent: February 12, 2013
    Assignee: Panasonic Corporation
    Inventor: Kenji Toyoda
  • Publication number: 20120288951
    Abstract: The present invention relates to the field of detection of components in gas phase, and in particular to detection of nitric oxide exhaled as a component of breath, using a liquid crystal assay format and a device utilizing liquid crystals as part of a reporting system.
    Type: Application
    Filed: April 27, 2012
    Publication date: November 15, 2012
    Applicant: PLATYPUS TECHNOLOGIES, LLC
    Inventors: Bharat Acharya, Avijit Sen, Nicholas Abbott, Kurt Kupcho