Abstract: An OBD system is provided for monitoring an ozone depletion system that includes a catalyst coating containing MnO2 applied to a heat exchange surface on a moving vehicle over which atmospheric air passes. A physical characteristic of the catalyst coating or a material containing a physical characteristic within the catalyst coating is sensed to determine the presence or absence of the catalyst coating for detecting catastrophic failure of the ozone depleting system and/or degradation or wear of the catalyst coating to ascertain the efficiency of the catalyst coating.

Abstract: A heat generation amount qr/r per unit flow amount of combustible substances supplied to a catalyst is estimated based on upstream and downstream temperature information and supplemental engine information. A deteriorated condition of the catalyst is detected based on a judgement whether or not the estimated heat generation amount is smaller than a predetermined judging value D.

Abstract: The invention relates to equipment for pretreatment of catalysts and/or catalytic testing that makes it possible to establish the material balance of a chemical reaction in the presence of very small amounts of solid catalyst under operating conditions of industrial use.

Abstract: The present invention provides a method for forming a substantially carbon- and oxygen-free conductive layer, wherein the layer can contain a metal and/or a metalloid material. According to the present invention, a substantially carbon- and oxygen-free conductive layer is formed in an oxidizing atmosphere in the presence of an organometallic catalyst using, for example, a chemical vapor deposition process. Such layers are particularly advantageous for use in memory devices, such as dynamic random access memory (DRAM) devices.

Abstract: Apparatus 1 for evaluating catalyst performance according to the invention comprises a reaction vessel 2 in which a plurality of catalysts S are disposed at a distance, supply pipes 3 for supplying a reactant gas into the reaction vessel 2, a plurality of measuring instruments 7 provided with gas sensors 71 for sensing the gas formed by the contact of the reactant gas with a plurality of catalysts S, and outputting signals according to the kinds and concentrations of the formed gas, and a calculating unit 8 for receiving the output signals from the plurality of measuring instruments 7 and identifying the kinds of the formed gas and calculating the concentrations thereof. With such a constitution, performance evaluation on a plurality of catalysts can be made concurrently, quick and in simple steps.

Abstract: The present invention provides a method for testing the accessibility of porous materials with regard to large, often high-molecular weight compounds and correlating said accessibility to the porous material's accessibility under conditions of use, i.e. the application conditions.

Abstract: Methods and devices for rapidly analyzing groups of reactions are disclosed. The method includes the steps of contacting a fluid sample from one of the reaction mixtures with a sorbent, trapping at least one component of the fluid sample on the sorbent, and detecting the at least one component of the fluid sample trapped on the sorbent. The contacting step, the trapping step, and the detecting step are carried out at least once for each of the reaction mixtures in rapid serial or parallel fashion. The present invention is useful for screening combinatorial libraries, especially libraries of catalysts made through parallel synthesis, but the disclosed methods and devices can be used to analyze a broad spectrum of chemical transformations.

Abstract: Methods for discovering optimum catalysts and/or reaction conditions for performing endo-or exothermic reactions, in particular gas-to-liquid reactions, are disclosed. A combinatorial approach is used to identify optimum catalysts and/or reaction conditions for performing the reactions. The reactions are performed in the channels of a microchannel reactor. These results can be used directly to optimize large scale reactions performed in a plurality of microchannel reactors, or can be correlated to useful catalysts and reaction conditions for use in large scale reactors by taking into consideration the heat transfer effects in the microchannel reactor and the large scale reactor. The method can advantageously be used to generate a database of combinations of catalyst systems and/or reaction conditions which provide various product streams, such that as market conditions vary and/or product requirements change, conditions suitable for forming desired products can be identified with little or no downtime.

Abstract: Computer programs and computer-implemented methods for monitoring the progress and properties of parallel chemical reactions. The invention repeatedly receives a measured value or values associated with the contents of each of a plurality of reactor vessels and displays the measured over the course of a combinatorial chemical reaction. Reaction parameters associated with individual reactor vessels are changed in response to the value measured during the reaction. Reaction parameters include temperature, pressure, stirring speed. The reaction occurring in one or more reactor vessels is quenched in response to values measured during the reaction. The measured values are used to calculate experimental results including temperature change, pressure change, percent conversion of starting material, and viscosity. The measured values and experimental results are displayed. In another aspect, the invention features a method for controlling a combinatorial chemical reactor.

Abstract: One of a pair of temperature sensor sections in a combustible gas sensor is covered with porous oxidizing catalytic layers (23, 24) for oxidizing a combustible gas, and the other is not covered with the oxidizing catalyst layers. The temperature sensor sections each have temperature sensitive portions (13, 14) made of a dense ceramic material, resistors (21, 22) buried therein and having a positive resistance temperature coefficient, current leads (31, 32, 41, 42) and voltage leads (33, 34, 43, 44). A method for detecting the deterioration of a catalyst which intends to eliminate the combustible gas, by the use of this combustible gas sensor is further disclosed. When a difference between temperatures of the pair of resistors or a difference between powers fed to the pair of resistors is in excess of a predetermined value, it is judged that the catalyst has been deteriorated.

Abstract: A method of and apparatus for detecting if a MOS gas sensor has been poisoned, the sensor having a sensor element for sensing a target gas and having a heater configured to heat the sensor element in response to a voltage being applied to the heater, the heater having an operating temperature which is selectively maintained by applying a first voltage thereto. The method includes reducing the voltage from the first voltage; and sensing a change in resistance of the sensor element, responsive to the reduction of the voltage from the first voltage, and comparing sensed changes with expected changes. The apparatus includes circuitry configured to reduce the voltage from the first voltage; and the same or different circuitry senses a change in resistance of the sensor element which is responsive to the reduction of the voltage from the first voltage, and compares sensed changes with expected changes.

Abstract: The performance of an anion exchange resin is evaluated on-line by measuring inorganic carbonic acid concentrations at the inlet and at the outlet of an ion exchange resin vessel (such as a demineralizer vessel) of an ion exchange apparatus such as a condensate water demineralization system. Moreover, an MTC (Mass Transfer Coefficient) with respect to the inorganic carbonic acid is calculated and the dynamic performance and/or degree of degradation of the anion exchange resin are evaluated. The degree of degradation of the anion exchange resin is evaluated from the MTC and the replacement timing, lifetime, and throughput capacity for the anion exchange resin are judged.

Abstract: A catalyst deterioration detecting device of the invention has exhaust emission purifying catalyst on an exhaust passage of an internal combustion engine and air-fuel ratio sensors provided upstream and downstream of the exhaust emission purifying catalyst, respectively, and detects the deterioration of the exhaust emission purifying catalyst based on the outputs of the air-fuel ratio sensors. An index characteristic value of catalyst deterioration is calculated from the outputs of the air-fuel ratio sensors, a time-lapse changing ratio of the calculated index characteristic value of catalyst deterioration is calculated, and the deterioration of the exhaust emission purifying catalyst is determined based on the calculated time-lapse changing ratio.

Abstract: Devices and methods for controlling and monitoring the progress and properties of multiple reactions are disclosed. The method and apparatus are especially useful for synthesizing, screening, and characterizing combinatorial libraries, but also offer significant advantages over conventional experimental reactors as well. The apparatus generally includes multiple vessels for containing reaction mixtures, and systems for controlling the stirring rate and temperature of individual reaction mixtures or groups of reaction mixtures. In addition, the apparatus may include provisions for independently controlling pressure in each vessel, and a system for injecting liquids into the vessels at a pressure different than ambient pressure. In situ monitoring of individual reaction mixtures provides feedback for process controllers, and also provides data for determining reaction rates, product yields, and various properties of the reaction products, including viscosity and molecular weight.

Abstract: In order to prevent a catalyst for an internal combustion engine from decreasing efficiency by deterioration after long time use of the catalyst, the decreased efficiency of the catalyst is determined, and the internal engine is controlled based on results of the determination so as to maintain high efficiency of the catalyst. The catalyst is installed in an exhaust pipe of the engine. Sensors for detecting conditions of exhaust gas both at upstream side and downstream side of the catalyst are provided, respectively. As for the sensor, for example, an oxygen sensor of which output varies stepwise at &lgr;=1, or a sensor of which output varies in proportion to air-fuel ratio can be used. Detected values of the sensors are taken into a control unit, eliminating efficiency and deteriorating degree of the catalyst are estimated by comparison of the detected values, and the engine is controlled so that the eliminating efficiency becomes maximum.

Abstract: Apparatus for testing catalyst candidates including a multi-cell holder e.g. a honeycomb or plate, or a collection of individual support particles that have been treated with solutions/suspensions of catalyst ingredients to produce cells, spots or pellets holding each of a variety of combinations of the ingredients and dried, calcined or treated as necessary to stabilize the ingredients in the cells, spots or pellets. The apparatus also includes structure for contacting the catalyst candidates with a potentially reactive feed stream or batch e.g., biochemical, gas oil, hydrogen plus oxygen, propylene plus oxygen, CCl2F2 and hydrogen, etc. The reaction occurring in each cell can be measured, e.g. by infrared thermography, spectroscopic detection of products or residual reactants, or by sampling, e.g. by multistreaming through low volume tubing, from the vicinity of each combination, followed by analysis e.g. spectral analysis, chromatography etc.

Abstract: The present invention relates, inter alia, to methodologies for the synthesis, screening and characterization of organometallic compounds and catalysts (e.g., homogeneous catalysts). The methods of the present invention provide for the combinatorial synthesis, screening and characterization of libraries of supported and unsupported organometallic compounds and catalysts (e.g., homogeneous catalysts). The methods of the present invention can be applied to the preparation and screening of large numbers of organometallic compounds which can be used not only as catalysts (e.g., homogeneous catalysts), but also as additives and therapeutic agents.

Abstract: Ozone-splitting catalytic converters can be monitored through the use of conductivity sensors for detecting ozone. Since such sensors rapidly attain operational readiness have low source sensitivities to other gases, and an adequate service life, they can be used in practical applications. Different methods of operation are capable of optimizing the ratio between ozone sensitivity and transverse axis sensitivity of the sensors.

Abstract: A method of making and screening an array of catalysts, said method comprising: (a) combining a first polymerization precursor material, a second polymerization precursor material and a first catalyst in a first region on a substrate; (b) combining a first polymerization precursor material, a second polymerization precursor material and a second catalyst in a second region on a substrate; (c) reacting the first and second polymerization material in said first and second regions; and (d) screening said first and second regions of said substrate for a measurable property or properties.

Abstract: Rapid screening for activities and selectivities of catalyst libraries having addressable test sites is achieved by contacting potential catalysts at the test sites with reactant streams forming product plumes at the adressable test sites. The product plumes are screened by translating a sample probe and/or the library to a position that one addressable site is in proximity to the sampling probe sample orifice and passing a portion of the reaction products through the sampling orifice forming a free jet expanded volume in at least one vacuum stage and passing a portion of the cooled and reduced pressure jet stream through an inlet orifice of a mass spectrometer for analysis. The mass spectrometric analysis may be combined with resonance enhanced multiphoton ionization methods of detection for very rapid library evaluation. Suitable reactors, microreactors, and product transfer sample microprobes for product transfer to a mass spectrometer are disclosed.

Abstract: Methods and apparatus for the preparation and use of a substrate having an array of diverse materials in predefined regions thereon. A substrate having an array of diverse materials thereon is generally prepared by delivering components of materials to predefined regions on a substrate, and simultaneously reacting the components to form at least two materials. Materials which can be prepared using the methods and apparatus of the present invention include, for example, covalent network solids, ionic solids and molecular solids. More particularly, materials which can be prepared using the methods and apparatus of the present invention include, for example, inorganic materials, intermetallic materials, metal alloys, ceramic materials, organic materials, organometallic materials, non-biological organic polymers, composite materials (e.g., inorganic composites, organic composites, or combinations thereof), etc.

Abstract: The present invention relates, inter alia, to methodologies for the synthesis, screening and characterization of organometallic compounds and catalysts (e.g., homogeneous catalysts). The methods of the present invention provide for the combinatorial synthesis, screening and characterization of libraries of supported and unsupported organometallic compounds and catalysts (e.g., homogeneous catalysts). The methods of the present invention can be applied to the preparation and screening of large numbers of organometallic compounds which can be used not only as catalysts (e.g., homogeneous catalysts), but also as additives and therapeutic agents.

Abstract: The present invention provides methods, compounds, and kits useful in the analysis of reaction products and components of reaction mixtures, and in certain embodiments for the rapid and simultaneous determination of enantiomeric ratios, percent conversions, and absolute configurations.

Abstract: Methods and apparatus for the preparation and use of a substrate having an array of diverse materials in predefined regions thereon. A substrate having an array of diverse materials thereon is generally prepared by delivering components of materials to predefined regions on a substrate, and simultaneously reacting the components to form at least two materials. Materials which can be prepared using the methods and apparatus of the present invention include, for example, covalent network solids, ionic solids and molecular solids. More particularly, materials which can be prepared using the methods and apparatus of the present invention include, for example, inorganic materials, intermetallic materials, metal alloys, ceramic materials, organic materials, organometallic materials, non-biological organic polymers, composite materials (e.g., inorganic composites, organic composites, or combinations thereof), etc.

Abstract: Methods and devices for rapidly analyzing groups of reactions are disclosed. The method includes the steps of contacting a fluid sample from one of the reaction mixtures with a sorbent, trapping at least one component of the fluid sample on the sorbent, and detecting the at least one component of the fluid sample trapped on the sorbent. The contacting step, the trapping step, and the detecting step are carried out at least once for each of the reaction mixtures in rapid serial or parallel fashion. The present invention is useful for screening combinatorial libraries, especially libraries of catalysts made through parallel synthesis, but the disclosed methods and devices can be used to analyze a broad spectrum of chemical transformations.

Abstract: The present invention discloses an apparatus and method for rapid synthesis and analysis of members of a combinatorial library. The apparatus includes a plurality of vessels for containing individual library members and a fluid handling system that apportions a test fluid about equally between each of the vessels. This allows for simultaneous screening of library members by detecting changes in test fluid following contact with individual library members. Fluid flow through each of the vessels is controlled using passive flow restrictors or active flow controllers to ensure that each library member contacts approximately the same amount of test fluid per unit time. The disclosed apparatus and method is especially useful for making inorganic oxide mixtures and for screening the mixtures based on their ability to catalyze the conversion of fluid reactants.

Abstract: Parallel flow reaction systems comprising four or more reaction channels are disclosed. Distribution systems, and parallel flow reaction systems comprising such distribution systems are also disclosed. Specifically, the distribution systems comprise a feed-composition subsystem for providing a different feed composition to each of the four or more reactors. In preferred embodiments, the feed composition subsystem comprises at least one set of four or more feed-component flow restrictors, each of the four or more feed-component flow restrictors having a flow resistance that varies relative to other flow restrictors in the set.

Abstract: A combinatorial process for simultaneously conducting multiple catalytic chemical reactions in parallel has been developed. At least one catalyst is contained in the reaction zones of a plurality of reactors, each reactor having a reactor insert placed within a sleeve and inserted into a well, the reaction zone of each reactor being formed between a fluid permeable structure attached to the sleeve and a fluid permeable end of the corresponding reactor insert. A fluid reactant is flowed through each reactor where it is contacted with the catalyst contained in the reaction zone to form an effluent. The effluents are removed from the effluent from the reactor and are analyzed.

Abstract: An article, apparatus and method for simulating poisoning and deactivating catalysts with catalyst poison compounds at least one catalyst poison compound selected from the group consisting of a compound comprising phosphorous, a compound comprising zinc compound and a compound comprising phosphorous and zinc.

Abstract: This invention is directed to a method of monitoring the relative activity of various heterogeneous catalysts by analyzing their bulk electrical properties such as specific conductivity or resistance. The difference between the resistance of fresh and spent catalysts is to be large (as high as four orders of magnitude). These large differences make this invention a very sensitive indicator of changes that may happen at the surface and/or in the bulk of the catalyst. The simplicity of this new invention renders it to be a sensitive potential on-line testing method of catalyst activity.

Abstract: The invention relates to a process for estimating a property of use, for example the activity of a catalyst or the ability to hold a radio-element in a solid mineral matrix, or a material MAB whose active element is AB. This process comprises the use of a descriptor DAB of the chemical bond between A and B, which has the dimension of an energy, and an index RAB that measures the property of use of said material. The invention also relates to a process for determining the chemical affinity of an element or a set of elements B for a matrix A with a descriptor DAB. The processes according to the invention advantageously can be used for the design of new materials whose use produces the formation or the modification of at least one chemical bond or makes it necessary to prevent the formation of said bond.

Abstract: A process is disclosed for checking the operatability of a nitrogen oxide storage catalyst which is used to remove the nitrogen oxides contained in the exhaust gas stream from a lean burn engine and which contains at least a nitrogen oxide storage material, a catalytically active component and optionally an oxygen storage material. The lean burn engine is operated with cyclic alternation of the air/fuel mixture from lean to rich and the nitrogen oxides contained in the exhaust gas are stored by the nitrogen oxide storage material in the presence of lean burn exhaust gas (storage phase) and is desorbed and converted in the presence of rich exhaust gas (regeneration phase).

Abstract: A reactor for conducting catalytic chemical reactions has been developed. The reactor has a well having an open end and a closed end. The reactor also has a sleeve having a top end and a bottom end. The bottom end of the sleeve is inserted within the open end of the well. A fluid permeable structure is attached to the sleeve spanning the cross-section thereby defining a chamber between the closed end of the well and the fluid permeable structure. The reactor also has a reactor insert having a fluid permeable end and a top end containing a first and a second fluid conduit. The fluid permeable end of the reactor is inserted within the open end of the sleeve. The first fluid conduit is in fluid communication with the chamber, and the second fluid conduit is in fluid communication with the fluid permeable end of the reactor insert.

Abstract: Apparatus for testing catalyst candidates including a multicell holder e.g. a honeycomb or plate, or a collection of individual support particles that have been treated with solutions/suspensions of catalyst ingredients to produce cells, spots or pellets holding each of a variety of combinations of the ingredients and dried, calcined or treated as necessary to stabilize the ingredients in the cells, spots or pellets. The apparatus also includes structure for contacting the catalyst candidates with a potentially reactive feed stream or batch e.g., biochemical, gas oil, hydrogen plus oxygen, propylene plus oxygen, CCl2F2 and hydrogen, etc. The reaction occurring in each cell can be measured, e.g. by infrared thermography, spectroscopic detection of products or residual reactants, or by sampling, e.g. by multistreaming through low volume tubing, from the vicinity of each combination, followed by analysis e.g.

Abstract: The present invention discloses methods and materials for constructing combinatorial libraries composed of organometallic compounds immobilized on solid supports and encoded with detectable tags. The encoded library of organometallic compounds is especially useful for rapidly screening large numbers of member compounds for catalytic performance. These immobilized catalysts can be pooled in a single reactor where they are screened for a predefined property, such as catalytic activity and selectivity.

Abstract: The invention pertains to an apparatus for testing samples of a solid material, such as a catalyst or an adsorbent, contained in a reactor tube, said apparatus comprising a holder for a tube and a flow module for generating a carrier fluid flow containing a probe through a tube positioned in the holder. The apparatus further comprises a magazine for tubes or means for accommodating a magazine for tubes, and means for replacing a tube positioned in the holder with a tube from the magazine.

Abstract: The present invention discloses methods and materials for constructing combinatorial libraries composed of organometallic compounds immobilized on solid supports and encoded with detectable tags. The encoded library of organometallic compounds is especially useful for rapidly screening large numbers of member compounds for catalytic performance. These immobilized catalysts can be pooled in a single reactor where they are screened for a predefined property, such as catalytic activity and selectivity.

Abstract: An apparatus and method for carrying out and monitoring the progress and properties of multiple reactions is disclosed. The method and apparatus are especially useful for synthesizing, screening, and characterizing combinatorial libraries, but also offer significant advantages over conventional experimental reactors as well. The apparatus generally includes multiple vessels for containing reaction mixtures, and systems for controlling the stirring rate and temperature of individual reaction mixtures or groups of reaction mixtures. In addition, the apparatus may include provisions for independently controlling pressure in each vessel, and a system for injecting liquids into the vessels at a pressure different than ambient pressure. In situ monitoring of individual reaction mixtures provides feedback for process controllers, and also provides data for determining reaction rates, product yields, and various properties of the reaction products, including viscosity and molecular weight.

Abstract: An apparatus and method for carrying out and monitoring the progress and properties of multiple reactions is disclosed. The method and apparatus are especially useful for synthesizing, screening, and characterizing combinatorial libraries, but also offer significant advantages over conventional experimental reactors as well. The apparatus generally includes multiple vessels for containing reaction mixtures, and systems for controlling the stirring rate and temperature of individual reaction mixtures or groups of reaction mixtures. In addition, the apparatus may include provisions for independently controlling pressure in each vessel, and a system for injecting liquids into the vessels at a pressure different than ambient pressure. In situ monitoring of individual reaction mixtures provides feedback for process controllers, and also provides data for determining reaction rates, product yields, and various properties of the reaction products, including viscosity and molecular weight.

Abstract: The present invention relates to a catalyst characterization apparatus, and in particular to an improved catalyst characterization apparatus which is capable of characterizing the surface of a catalyst more accurately by a volumetric method without requiring a pre-treatment step which may vary the characteristics of the catalyst as well as without exposing the catalyst in air, by combining a dynamic flow type reactor with a volumetric type adsorption apparatus, whereby it is possible to accurately characterize the catalyst during an actual reaction. It is possible to accurately characterize the various catalysts and to characterize the catalyst during the reaction, alternately and/or continuously, by combining a dynamic flow type reactor with a volumetric type characterization apparatus as well as a dynamic flow type characterization apparatus.

Abstract: In order to prevent a catalyst for an internal combustion engine from decreasing efficiency by deterioration after long time use of the catalyst, the decreased efficiency of the catalyst is determined, and the internal engine is controlled based on results of the determination so as to maintain high efficiency of the catalyst. The catalyst is installed in an exhaust pipe of the engine. Sensors for detecting conditions of exhaust gas both at upstream side and downstream side of the catalyst are provided, respectively. As for the sensor, for example, an oxygen sensor of which output varies stepwise at &lgr;=1, or a sensor of which output varies in proportion to air-fuel ratio can be used. Detected values of the sensors are taken into a control unit, eliminating efficiency and deteriorating degree of the catalyst are estimated by comparison of the detected values, and the engine is controlled so that the eliminating efficiency becomes maximum.

Abstract: A method for isolating an active catalyst from a library of compounds that are potential catalysts is disclosed. The method involves providing a library which comprises a plurality of discrete solid supports, each solid support having a different organic compound bound thereto; and providing a reaction solution in a reaction vessel, the reaction solution containing the reactant or reactants necessary for a chemical reaction to occur in the presence of a catalyst for that reaction. The library and the reaction solution are then combined in the reaction vessel, and then one of the discrete solid supports is detected that is characterized by a temperature change in said solution greater than the temperature change of a plurality of other of said discrete solid supports in said solution. The detected solid support carries an active catalyst for the chemical reaction. Continuous flow apparatus for carrying out the method is also disclosed.

Abstract: A process for modifying a triacylglycerol stock, such as a vegetable oil stock, to better control fluidity is provided. The process includes interesterifying the triacylglycerol stock in the presence of a basic catalyst while monitoring the absorbance of the reaction mixture. A modified triacylglycerol stock produced by partial interesterification as well as plastic spreads and water-in-oil emulsions which include the partially interesterified triacylglycerol stock are also provided.

Abstract: In an HF alkylation process where an acid catalyst regeneration column separates HF acid from ASO and water to provide regenerated catalyst for a catalyst circulation stream, and where buildup of ASO in the catalyst circulation stream is encountered, an improved control scheme uses an on-line analyzer/controller to maintain desired concentrations of HF acid, or ASO or water in the catalyst circulation stream. In one embodoment, a continuously flowing catalyst slip stream is piped to the analyzer/controller for simultaneously determining concentration of HF acid, ASO and water, and in a preferred embodiment the ASO concentration is maintained at a desired low level by manipulating temperature of a stripping fluid charged to a lower section of the column. An alternate manipulated variable is temperature of the acid catalyst feed to the regenerator column. Alternate controlled variables are the HF acid, and water concentration in the catalyst circulation stream.

Abstract: An apparatus for evaluating a solid catalyst which can enlarge a range of an applied fluid used for an evaluation of a performance of the solid catalyst and can accurately evaluate the performance of the solid catalyst on a laboratory scale and a method of evaluating a solid catalyst using the apparatus are provided.

Abstract: The present invention discloses a method for improving the speed and sensitivity of optical spectroscopic techniques for remote detection of trace chemical species in a carrier gas. The disclosed method can be applied to any optical spectroscopic detection technique whose sensitivity decreases as the total pressure of the sample decreases. The method employs an inert and non-absorbing buffer gas to supplement the pressure exerted by the carrier gas. This ensures that the total pressure of the sample, and hence sensitivity of the detection technique, remains high. The method is especially useful when measuring concentration of chemical species produced at small rates, and therefore should prove useful for rapid serial screening of combinatorial libraries of compounds.

Abstract: Apparatus and process for real time analysis of the intermediates and products of a gas phase chemical reaction catalyzed by a particulate catalyst. Real time analysis is conducted under high vacuum using a detection device contained within a high vacuum chamber. The reactor is connected to the vacuum chamber but is outside thereof, allowing the reactor to be operated either at high vacuum or under moderate pressure. Reactors and reactor feed manifolds of varying configuration may be interchangeably connected to the vacuum chamber on an essentially modular basis. Only a single vacuum system is required for the apparatus. Reaction products may also be analyzed by methods such as gas chromatography. Simultaneously with real time analysis of reaction products and intermediates, infrared, ultraviolet other reflected electromagnetic analyses may be conducted on the reacting gases or catalyst surface.

Abstract: A reaction cell system for measurement of catalyst demand includes a spherical chamber having an inlet with a diametrically opposed outlet. An optical cylinder traverses the spherical chamber above an agitator maintained at the bottom thereof. The optical cylinder has a slit passing therethrough adjacent a wall of the spherical cylinder such that laminar and uniform flow of fluid within the chamber passes through the slit. The valving between the inlet and outlet of the chamber is such that the inlet valve opens before and closes after similar actuation of the outlet valve. A source of catalyst and indicator communicate with diaphragm dispensers which are operative to inject precise volumes of catalyst and indicator into the spherical chamber. A valve network allows for passage of the catalyst and indicator into the chamber or into measurement standards. Additionally, the valve network communicates with the source of fluid that feeds the chamber to allow for complete and total flushing of the system.

Abstract: A laboratory scale fluid catalytic cracking apparatus and method of use thereof, which provides cracking performance that emulates commercial riser cracking. The apparatus includes a reactor having a removable feed injector to quickly facilitate changing hydrocarbon contact time without varying the feed rate or diluent rates, or catalyst charge, and also without the expense of a new reactor. The feed injector is a tube within a tube design. The feed injector allows hydrocarbon feed as well as fluidization gas to be delivered to a prescribed axial position within a catalyst bed in the reactor to directly affect hydrocarbon contact time. The reactor also includes a conical bottom head having a conical section and a lower fluidization gas nozzle connected at its apex. The total included angle of the conical section may vary between 10.degree. and 1700.degree.

Abstract: A multicell holder e.g. a honeycomb or plate, or a collection of individual support particles, is treated with solutions/suspensions of catalyst ingredients to produce cells, spots or pellets holding each of a variety of combinations of the ingredients, is dried, calcined or treated as necessary to stabilize the ingredients in the cells, spots or pellets, then is contacted with a potentially reactive feed stream or batch e.g., biochemical, gas oil, hydrogen plus oxygen, propylene plus oxygen, CC12F2 and hydrogen, etc. The reaction occurring in each cell can be measured, e.g. by infrared thermography, spectroscopic detection of products or residual reactants, or by sampling, e.g. by multistreaming through low volume tubing, from the vicinity of each combination, followed by analysis e.g. spectral analysis, chromatography etc, or by observing temperature change in the vicinity of the catalyst e.g. by thermographic techniques, to determine the relative efficacy of the catalysts in each combination.