Abstract: An automatic sample testing machine for testing samples stored in test cards. The machine has a test sample positioning system for moving a tray containing a plurality of test sample cards and fluid receptacles among various stations in the machine. The machine has a diluting station for adding a predetermined quantity of diluent to the receptacles as needed. A pipetting station transfers fluid from one receptacle to another. A vacuum station is provided having a vacuum chamber moveable relative to the tray between upper and lower positions. The chamber cooperates with the tray to make a sealing engagement with the top surface of the tray when it is lowered to the lower position. A vacuum generator supplies vacuum to the chamber. When the vacuum is released from the chamber, the fluid samples are loaded into the cards from the receptacles.

Abstract: Monitoring apparatus comprises a support device for receiving a plurality of items to be monitored in an array, each item having a unique machine-readable identifying reference associated therewith, the arrangement being such that the items are movable to different positions in the array; a sensor device for intermittently and repeatedly monitoring each item in the array to monitor changes in a variable associated with each item and to read the reference associated with each item; device for supplying data to the monitored variable and machine-readable reference of each item to a computer, wherein the computer relates the monitored variable to the reference to each item independently of the position of the item in the array.

Abstract: A sample card transport station moves a test sample card from an incubation station for the card to a transmittance and fluorescence optical station in a sample testing machine. The sample card transport station has a drive belt and an associated stepper motor. The belt supports the card from one side of the card. A ledge having a card slot is disposed above the belt. The card is snugly received within the card slot, and supported from below by the drive belt and rollers for the belt. When the motor turns the belt, the belt grips the card and slides the card along the slot to the optical stations, without any slippage between the belt and the card. This construction provides for precise control over the movement of the card.The fluorescence station has a linear flash lamp that illuminates a column of the wells of the cards simultaneously. A reference detector and dichromatic beam splitter design is used to insure that the fluorescence measurements are independent of lamp output changes over time.

Abstract: An improved automated immunoassay analyzer including a high throughput automated immunoassay system which can perform high volume testing on a broad range of analytes while selecting from among a diverse set of immunoassays for any given sample. The immunoanalyzer has the capacity to perform a wide range of different types of immunoassays by facile storage and automated combination aboard the instrument among a wide variety of different types of reagents and heterogenous immunoassay beads stored on-board the instrument. The automated design allows reduced user interface (e.g., tests are performed automatically from computer input) including the ability to order, perform and reassay tests reflexively based on test results without operator intervention. Further, the inventive analyzer is not sample tube specific; that is, an instrument that can accept sample tube sizes within a broad size range.

Abstract: An improved automated immunoassay analyzer including a high throughput automated immunoassay system which can perform high volume testing on a broad range of analytes while selecting from among a diverse set of immunoassays for any given sample. The immunoanalyzer has the capacity to perform a wide range of different types of immunoassays by facile storage and automated combination aboard the instrument among a wide variety of different types of reagents and heterogenous immunoassay beads stored on-board the instrument. The automated design allows reduced user interface (e.g., tests are performed automatically from computer input) including the ability to order, perform and reassay tests reflexively based on test results without operator intervention. Further, the inventive analyzer is not sample tube specific; that is, an instrument that can accept sample tube sizes within a broad size range.

Abstract: A disk for holding, centrifuging and microscopically viewing fluid samples is provided. The disk includes a plurality of reaction wells radiating outwardly and includes a barrier to restrain particles during centrifugation. This disk is used in the disclosed apparatus and method for blood typing and related procedures. The apparatus comprises sample loading, mixing, centrifuging, incubating, viewing and sterilizing stations. Additionally, a photomicrograph of the sample is taken, digitized, displayed, stored and printed along with corresponding test results and interpretation.

Abstract: A system for processing biomolecules comprising, a plurality of manifolds, each manifold having a holder portion and a number of peg members extending therefrom, a plurality of plate or strip means, each supporting a number of wells adapted to receive the manifold peg members, a processing device which comprises several processing units in the form of at least one heating plate unit adapted to receive the well plate or strip means for heating the wells thereof, at least one wash unit having a plurality of wash wells, each wash well being adapted to receive one or more manifold peg members and having at least one inlet and at least one outlet for wash liquid, and a holder device for holding a plurality of manifolds during processing in and transfer between different units of the processing device.

Abstract: An automatic sample pretreatment device is provided which is capable of conducting a series of treatments or reactions from pretreatment to measurement automatically in a short time by employing a separate reaction system from the reaction system for measurement.

Abstract: A multi-item analyzer includes a first analyzing module for performing analysis items having a larger request in number arranged in the upstream side of a transporting line, and a second analyzing module for performing analysis items having a smaller request in number arranged in the downstream side. A sample sampling position for the analyzing module in the upstream side is provided on the transporting line, and a sample sampling position for the analyzing module in the downstream side is provided on a rack receiving area.

Abstract: An automatic sample testing machine for testing samples stored in test cards. The machine has a test sample positioning system for moving a tray containing a plurality of test sample cards and fluid receptacles among various stations in the machine. The machine has a diluting station for adding a predetermined quantity of diluent to the receptacles as needed. A pipetting station transfers fluid from one receptacle to another. A vacuum station is provided having a vacuum chamber moveable relative to the tray between upper and lower positions. The chamber cooperates with the tray to make a sealing engagement with the top surface of the tray when it is lowered to the lower position. A vacuum generator supplies vacuum to the chamber. When the vacuum is released from the chamber, the fluid samples are loaded into the cards from the receptacles.

Abstract: A systems for test elements used for clinical chemical analyses has several test elements, each of which is individually sealed to be impermeable to water vapor. The method provides for the removal of test elements and protects the test elements contained in it against effects from the outside.

Abstract: A method and apparatus are provided for calibrating a sensor for determination of analyte concentration. The meter includes a sensor for receiving a user sample to be measured and a processor for performing a predefined test sequence for measuring a predefined parameter value. A memory can be coupled to the processor for storing predefined parameter data values. A calibration code is associated with the sensor and read by the processor before the user sample to be measured is received. The calibration code is used in measuring the predefined parameter data value to compensate for different sensor characteristics.

Abstract: An automatic sample testing machine for testing samples stored in test cards. The machine has a test sample positioning system for moving a tray containing a plurality of test sample cards and fluid receptacles among various stations in the machine. The machine has a diluting station for adding a predetermined quantity of diluent to the receptacles as needed. A pipetting station transfers fluid from one receptacle to another. A vacuum station is provided having a vacuum chamber moveable relative to the tray between upper and lower positions. The chamber cooperates with the tray to make a sealing engagement with the top surface of the tray when it is lowered to the lower position. A vacuum generator supplies vacuum to the chamber. When the vacuum is released from the chamber, the fluid samples are loaded into the cards from the receptacles.

Abstract: The embodiments disclosed relate to determination of an item of interest in a sample. In one method, a process path comprising a process lane including a process step performance lane where a process step is performed, and a process step avoidance lane where the process step is avoided is provided. A container holding the sample is moved along the process path. The sample is introduced to the container. A reagent is introduced to the container. The sample and the reagent are mixed in the container. The container is selectively positioned in a selected one of the process step performance lane and the process step avoidance lane. The item of interest in the sample is determined based upon a reaction between the sample and the reagent.

Abstract: A sample card transport station moves a test sample card from an incubation station for the card to a transmittance and fluorescence optical station in a sample testing machine. The sample card transport station has a drive belt and an associated stepper motor. The belt supports the card from one side of the card. A ledge having a card slot is disposed above the belt. The card is snugly received within the card slot, and supported from below by the drive belt and rollers for the belt. When the motor turns the belt, the belt grips the card and slides the card along the slot to the optical stations, without any slippage between the belt and the card. This construction provides for precise control over the movement of the card.The fluorescence station has a linear flash lamp that illuminates a column of the wells of the cards simultaneously. A reference detector and dichromatic beam splitter design is used to insure that the fluorescence measurements are independent of lamp output changes over time.

Abstract: Automatic immunological assay apparatus comprising reaction wells in which there are deposited quantities of samples to be analyzed and of reagents, the reaction wells being grouped in modules (40) that are moved in translation, sliding between rails that define a U-shaped track (24), running from automatic reaction well feed device (26) to device (28) for ejecting the wells after use.

Abstract: Disclosed is an automated supplying system for supplying liquid samples and test strips to an analyzer having a receiving section which receives test strips dipped in liquid samples one by one, a section at which optical characteristics of test pads provided on the received test strips are measured and a section for calculating analytical results of the respective components based on the respective optical characteristics obtained by the measurement.

Abstract: This invention provides an automated chemical analyzer capable of automatically analyzing a plurality of samples for at least two different analytes. The analyzer includes a plurality of assay resource stations and an analyzer control means. Each assay resource station includes an assay resource capable of performing a predetermined operation upon a sample-containing reaction vessel within a fixed indexing time. The analyzer control means includes scheduling means for allocating assay resources to one of the reaction vessels as a function of that time cycle and a transfer control means for controlling transfer of reaction vessels directly from one assay resource station to another according to a chronology selected from a plurality of different predetermined chronologies.

Abstract: A reaction apparatus is provided which is suitable for automatic immunoassay equipment and is capable of conducting treatments in reaction vessels for different reaction conditions such as reaction time and treatment method like a one-step method and a two-step method. The apparatus comprises a conveying mechanism for conveying vessels containing a objective measurement substance around a rotation center. The conveying mechanism comprises a fixed disk 1 for guiding the vessels 5 along a spiral lane 2, and a rotation disk 3 for guiding the vessels 5 along radial lanes. The vessels 5 are inserted at intersection points of the spiral lane and the radial lanes, and are conveyed with the rotation of the radial lanes along the spiral lane. The mechanism is constituted such that the vessels 5 for long-time treatment and the vessels for short-time treatment are inserted to the same insertion position and the vessels 5 for short-time treatment is taken out from an intermediate way of the conveying route.

Abstract: When reagent was discharged in a physiological tissue reagent treatment apparatus, it was troublesome to retain the sample so that it was not discharged together with the reagent. This apparatus offers an improvement on this point, saves work involved in reagent treatment and enables lower costs to be attained. Samples 70 are held in separate sample containers 8. The base of this sample container 8 comprises a mesh 64. Consequently, when the sample container 8 is inserted in a reagent bath 6 in which reagent has collected, reagent flows from this mesh 64 into the container 8. Reagent may flow also from a flow hole 66. The reagent which has flowed into the container 8 acts on the sample 70, and reagent treatment takes place. The reagent in a plurality of the sample containers 8 set in a container holder 10, is then aspirated by a pump 30, or by a nozzle inserted together with the container 8 in the reagent bath, via the mesh 64 of the container.

Abstract: A luminometer for determining the composition of a specimen sample includes an annular guide path for sample containing cuvettes within a light tight housing. A rotor moves spaced segments through the guide path with the cuvettes positioned between the segments. The luminometer further includes one or two detector assemblies coupled to the housing and positioned to view and detect light emitted by cuvettes as they pass along the guide path between segments. A cuvette is advanced around the housing via the rotor and rotor segments and when the cuvette reaches a predetermined position on the housing, a reagent, such as a base, is added to the cuvette to initiate a chemiluminescent reaction within the cuvette and provide an emission of light energy in a predetermined spectral range. The luminometer has a waste aspiration probe to remove the contents of the cuvette after it passes the detector.

Abstract: An automatic chemistry analyzer is provided having a high throughput and a high reliability. The analyzer uses nephelometric and turbimetric analyzers to analyze a wide variety of parameters within liquid samples typically generated in, for example, a large medical testing laboratory. The machine employs a unique probe and stirring rod assembly mounted at a slight angle with one another using rack and pinion assemblies so that the lower end of the probe and the lower end of the stirring rod are in very close proximity to one another. This feature allows the machine to be used in unusually small reaction cuvettes. The analysis machine also includes an onboard control sample so that the machine can be programmed to periodically calibrate its analyzing equipment during the course of normal operation.

Abstract: Aliquot of a urine sample is placed in a first automated analyzer sampling cup and a known standard is placed in a second cup. The urine sample and standard are transferred to separate cuvettes and at least one reagent composition in an aqueous medium is injected into the cuvette. The reagent composition contains a compound to remove substances in the urine interfering with a calorimetric reaction, a compound to convert B-hydroxybutyric acid in the urine to acetoacetic acid in the presence of nicotinamide adenine dinucleotide and reading at a specified wavelength to determine quantitatively the total ketone bodies in the patient's urine.

Abstract: A sample card transport station moves a test sample card from an incubation station for the card to a transmittance and fluorescence optical station in a sample testing machine. The sample card transport station has a drive belt and an associated stepper motor. The belt supports the card from one side of the card. A ledge having a card slot is disposed above the belt. The card is snugly received within the card slot, and supported from below by the drive belt and rollers for the belt. When the motor turns the belt, the belt grips the card and slides the card along the slot to the optical stations, without any slippage between the belt and the card. This construction provides for precise control over the movement of the card.

Abstract: A positioning system for a sample testing machine includes a base pan and a set of independent drive systems for sliding a sample tray across the base pan. Each of the drive systems includes a paddle that engages a side of the sample tray. The paddle is slideably mounted to a shaft with a collar that slides over the shaft. A motor and drive belt is provided to move the collar along the shaft, causing the paddle to engage the side of the sample tray and slide the sample tray across the base pan. Track sections are provided in the base pan to prevent the sample tray from rotating as the paddle slides the sample tray across the base pan.

Abstract: A high throughput chemical synthesis system utilizing cylindrical reaction vessels is disclosed. Reaction vessels are utilized which include a tubular member adapted for placement of electronically readable identifying indicia thereon. The identifying indicia are representative of reaction conditions within the tubular member and of one or more reagents utilized in a reaction within the tubular members. A method of performing chemical synthesis on solid phase reactive material within a plurality of reaction vessels using a plurality of reaction stages resulting in final products and employing identifying indicia representing the reaction stages is also disclosed. The method includes reading the identifying indicia located on the reaction vessels, reacting one or more reagents within the reaction vessels under particular reaction conditions which may be determined by reading the identifying indicia, thereby synthesizing chemical compounds within the reaction vessels.

Abstract: A biopsy apparatus, including: a microplate having defined therein a plurality of vertical wells; and a layer of film disposed over the vertical wells to prevent the evaporation of liquid therefrom, the layer of film being penetrable by a pipette tip to access one of the vertical wells to add liquid to or withdraw liquid from the vertical well, the layer of film being resealable to reseal the area of penetration of the pipette tip when the pipette tip is withdrawn, in order to prevent evaporation of liquid from the vertical well.

Abstract: A physiological tissue sample on a glass slide is treated by a reagent. A reagent bath is formed so that its horizontal depth becomes progressively larger from the lower part to the upper part. In a first treatment mode, a small amount of reagent is introduced in the reagent bath, and a sample plate is introduced into the bath up to a first treatment position. In a second treatment mode, a large amount of reagent is introduced in the reagent bath, and a sample plate is introduced into the bath up to a second treatment position.

Abstract: Unused reaction vessels and unused nozzle tips are arranged in a matrix on a vessel magazine and a tip magazine, respectively. A carrying mechanism for moving a gripping mechanism along X- and Y-axes seizes unused nozzle tips on the tip magazine one by one in order, and transfers them to a tip attaching station. The carrying mechanism also seizes unused reaction vessels on the vessel magazine one by one in order starting from one end of the first row. A delivery mechanism, after having attached a nozzle tip on the tip attaching station to a nozzle holder, pours sample and reagent into a reaction vessel on a delivery station. The reaction vessel is carried by a gripping mechanism to an incubator where the mixture of sample and reagent is incubated. After incubation, the reaction vessel is transferred to a shipper station where the reaction solution is extracted by suction with a shipper nozzle which introduces the solution into the flow cell of a measuring device.

Abstract: An automatic sample testing machine for testing samples stored in test cards. The machine has a test sample positioning system for moving a tray containing a plurality of test sample cards and fluid receptacles among various stations in the machine. The machine has a diluting station for adding a predetermined quantity of diluent to the receptacles as needed. A pipetting station transfers fluid from one receptacle to another. A vacuum station is provided having a vacuum chamber moveable relative to the tray between upper and lower positions. The chamber cooperates with the tray to make a sealing engagement with the top surface of the tray when it is lowered to the lower position. A vacuum generator supplies vacuum to the chamber. When the vacuum is released from the chamber, the fluid samples are loaded into the cards from the receptacles.

Abstract: The analytical device comprises a conveyor for conveying cuvettes to one or more stations for processing samples for analysis in the cuvettes. The processing stations comprise means for removing individual cuvettes from the conveyor, transferring the cuvettes to a processing position and returning the cuvettes to the conveyor after processing.

Abstract: An analyzer for performing automated assay testing. The analyzer includes a storage and conveyor system for conveying cuvettes to an incubation or processing conveyor, a storage and selection system for test sample containers, a storage and selection system for reagent containers, sample and reagent aspirating and dispensing probes, a separation system for separating bound from unbound tracer or labeled reagent, a detection system and date collection/processing system. All of the subunits of the machine are controlled by a central processing unit to coordinate the activity of all of the subunits of the analyzer. The analyzer is specifically suited for performing heterogeneous binding assay protocols, particularly immunoassays.

Abstract: An automated analytical instrument for conducting assays for components of interest in fluid samples. The instrument includes a testing system for assaying a fluid sample for a component of interest, a fluid dispensing assembly, an assembly for providing an assay module to the testing system and a fluid sample holding tray transport assembly for transporting a fluid sample holding tray carrying fluid sample holding containers to the fluid dispensing assembly and away from the fluid dispensing assembly. The transport assembly includes a conveyor, a fluid sample holding tray loading unit and a fluid sample holding tray unloading unit. The conveyor includes a carriage which is slidably mounted on a rail and moved along the rail by an endless belt which is fixedly attached to the carriage and driven by a reversible motor. In the operation of the instrument, one or more fluid sample holding trays are placed onto the fluid sample holding tray loading unit.

Abstract: A magnetic conveyor system for transporting test samples in tubes disposed in a sample rack having a magnetic or magnetically attractive region is described. The magnetic conveyor system includes a drive system, a magnet coupled to the drive system and movable in response to the drive system and a tray having a first surface adapted to receive the sample rack. The magnet is spaced a predetermined distance from the first surface of the tray such that the magnet provides a magnetic force at the surface of the tray. The magnetic force engages the magnetically attractive region of the sample rack disposed on the tray to thereby move the sample rack along the first surface of the tray in response to movement of the drive system. When the tray reaches the end of the rack it is moved onto a processing queue tray where it is available for test purposes. A barcode reader reads a bar code on each test sample as it is placed on the process queue to identify one or more tests to perform.

Abstract: A positioning system for a sample testing machine includes a base pan and a set of independent drive systems for sliding a sample tray across the base pan. Each of the drive systems includes a paddle that engages a side of the sample tray. The paddle is slideably mounted to a shaft with a collar that slides over the shaft. A motor and drive belt is provided to move the collar along the shaft, causing the paddle to engage the side of the sample tray and slide the sample tray across the base pan. Track sections are provided in the base pan to prevent the sample tray from rotating as the paddle slides the sample tray across the base pan.

Abstract: A vessel holder for receiving a number of vessels is useful in an automated analyzer. To increase the number of vessels which can be received in the analyzer and to simplify the device for reading bar code labels, the vessel holder has an elongate body manufactured in one piece and containing a single straight row of identical elongate chambers. Each chamber is for receiving one vessel. All chambers have a common base with respect to which they are perpendicularly disposed. Adjacent chambers are separated by a partition. The inside of a side wall of each chamber bears a first bar code label for detecting the absence of a vessel in the chamber, and the outside of a side wall of each chamber bears a second bar code label for detecting the position of the chamber in the vessel holder. The first and the second bar code labels are readable by a bar code reader from one and the same side of the vessel holder.

Abstract: This invention provides an automated chemical analyzer with improved processing flexibility and ease. In one embodiment of this invention, the analyzer includes an incubation station, a wash station and a read station. The incubation station includes an elongated, movable track to carry reaction vessels along an incubation path, the wash station includes a movable track to carry vessels along a wash-cycle path, and the read station is adapted to move vessels along a read path. A first transfer station is positioned adjacent a first end of the wash-cycle path to transfer vessels from the incubation path to the wash-cycle path and a second transfer station is positioned adjacent a second end of the wash-cycle path and a first end of the read path for selectively transferring a vessel from the wash-cycle path to either the incubation path or the read path.

Abstract: A portable specimen transporting cassette for use with an automated specimen handling system The cassette includes a body portion, an electronic programmable memory device attached to the body portion, and an electrical conductor coupled to the memory device. The body portion includes right and left opposing sidewalls, and a substantially open front face between the opposing sidewalls. A plurality of ribs compartmentalize the body portion into superimposed sections, each capable of containing a specimen. The substantially open front face permits the specimens to be inserted into and withdrawn from the cassette. The electrical conductor interfaces with the specimen handling system and permits communication between the memory device and the specimen handling system. The cassette may include two separable portions which can be separately distributed for processing of sorted specimens therein.

Abstract: The invention lies in the field of analyzing sample liquids with the aid of test strips and addresses an evaluation instrument for test strips where test strips are transported by a grabber. The grabber is attached to a guide arm that is moved in one spatial direction. A redirecting mechanism serves to apply the movement of the guide arm to the grabber such that a movement in at least two spatial directions is carried out.

Abstract: A luminometer for determining the composition of a specimen sample includes an annular guide path for sample containing cuvettes within a light tight housing. A rotor moves spaced segments through the guide path with the cuvettes positioned between the segments. The luminometer further includes one or two detector assemblies coupled to the housing and positioned to view and detect light emitted by cuvettes as they pass along the guide path between segments. A cuvette is advanced around the housing via the rotor and rotor segments and when the cuvette reaches a predetermined position on the housing, a reagent, such as a base, is added to the cuvette to initiate a chemiluminescent reaction within the cuvette and provide an emission of light energy in a predetermined spectral range. The luminometer has a waste aspiration probe to remove the contents of the cuvette after it passes the detector.

Abstract: A transport system for instruments utilized in the analysis of fluids and, more particularly, a transport system which is adapted to be employed in the automated analysis of blood samples. The transport system including cassette transporting and filling structure is provided to extend over and operatively interconnect various stations of a blood analysis apparatus consisting of a blood sample and reagent supply holder, a storage unit for empty cassettes, a carousel or rotor containing an incubator chamber and a chamber at room-temperature for the receipt and filling with blood samples of cassettes, a centrifuge and an automated optical readout rotor.

Abstract: A disposal system for stacking card-like objects neatly in a magazine. The cards enter the disposal system via a card entrance slot. A push plate located adjacent the slot pushes the cards past a pair of resilient snap elements in the sides of the magazine. A pressure plate is located behind the snap elements and biases the cards that have been pushed over the snap elements forward towards the rear of the snap elements. The cards are maintained in a stacked condition between the snap elements and the pressure plate. When a card is inserted into the card slot, the push plate is operated to an extended position, in which it pushes the card past the snap elements against the cards stacked between the snap elements and the pressure plate. The push plate then retracts, so as to enable another card to enter into the card slot. The user of the machine removes the magazine from the machine when the need arises or when the magazine is fully loaded with cards.

Abstract: An analyzer automatically performs analytical operations in which liquid samples for analysis and required reagents are held in suitable vessels. To increase the number of vessels which can be received in the analyzer and to simplify the device for reading the bar code labels, the analyzer contains at least two vessel holders, a bar code reader, and means for automatically adjusting the focal range and the bar code reader. The vessel holders are disposed parallel to one another in the analyzer. A number of vessels of the same kind (for example, sample-containing vessels) are disposed in each vessel holder. Each vessel holder has an elongate body manufactured in one piece and contains a single straight row of identical elongate chambers for receiving one vessel. All chambers have a common base and are disposed perpendicularly thereto. Adjacent chambers are separated by a partition.

Abstract: A chain incubator or conveyor, and method of use in an analyzer, wherein an endless chain is formed of repeating members and each comprising a link, element support, a cover, and means for biasing the cover onto the support with an article such as a test element between them. The members are linked together by a pair of pivot pins, and the chain is engaged by a drive sprocket and an idler sprocket.

Abstract: A sample card transport station moves a test sample card from an incubation station for the card to a transmittance and fluorescence optical station in a sample testing machine. The sample card transport station has a drive belt and an associated stepper motor. The belt supports the card from one side of the card. A ledge having a card slot is disposed above the belt. The card is snugly received within the card slot, and supported from below by the drive belt and rollers for the belt. When the motor turns the belt, the belt grips the card and slides the card along the slot to the optical stations, without any slippage between the belt and the card. This construction provides for precise control over the movement of the card.

Abstract: A biochemical analysis system includes a depositing mechanism which deposits a sample liquid on a chemical analysis slide having a reagent layer, an incubator which incubates the chemical analysis slide with the sample liquid at a predetermined temperature for a predetermined time, a transfer mechanism which loads the slide in the incubator and removes it therefrom, and an optical density measuring system which measures the optical density of the chemical analysis slide after incubation and determines the concentration of a specific biochemical component in the sample liquid through the optical density of the chemical analysis slide. The incubator has a rotary body in which a slide discarding hole is formed at the center thereof and a plurality of slide holding portions are formed to extend from the outer peripheral surface of the rotary body toward the center of the rotary body and communicate with the slide discarding hole.

Abstract: A cuvette, to be used for measuring the properties of liquid contained therein by applying a measuring beam of light from a direction intersecting the vertical axis of the cuvette, includes a rectangular or square-outlined portion on the top thereof as viewed in a horizontal cross section, a cylindrical portion below the top portion, and a lower rectangular or square portion provided vertically below the cylindrical portion and having four sides parallel to these of the top rectangular portion, respectively. Thus, the cuvette does not unfavorably rotate when measuring the absorption of light transmitted therethrough. Further, an apparatus for transporting the aforementioned transparent cuvette, accurately controls the position of the cuvette during transportation so that a flat surface thereof can be irradiated with a measuring beam of light.

Abstract: The invention provides a method for analyzing samples for different analytes. A plurality of assay resource stations are provided, each of which includes an assay resource capable of performing a predetermined operation upon a reaction vessel within a time cycle of fixed duration, as is an analyzer control means. Information identifying two samples and the analyte to be determined in each is provided to the analyzer control means. Assay resource requirements for the first assay are determined as a function of an integral number of time cycles and appropriate time cycles of each required assay resource are allocated to the first assay. Assay resource requirements for the second assay are also determined as a function of an integral number of time cycles and time cycles are allocated to the second assay according to the availability of the assay resources.

Abstract: An analyzer for performing automated assay testing. The analyzer includes a storage and conveyor system for conveying cuvettes to an incubation or processing conveyor, a storage and selection system for test sample containers, a storage and selection system for reagent containers, sample and reagent aspirating and dispensing probes, a separation system for separating bound from unbound tracer or labeled reagent, a detection system and date collection/processing system. All of the subunits of the machine are controlled by a central processing unit to coordinate the activity of all of the subunits of the analyzer. The analyzer is specifically suited for performing heterogeneous binding assay protocols, particularly immunoassays.

Abstract: This invention relates to a novel, fully automated spectrophotometric analyzer and method used for testing blood samples in the clinical laboratory for thrombosis and hemostasis properties. The analyzer tests samples in a fully randomized format, and is fully automated in the areas of specimen handling, sample preparation, optical inspection, data analysis and total quality control for imprecision and bias.