Condition Or Time Responsive Patents (Class 436/50)
  • Patent number: 10379103
    Abstract: A urine sample testing apparatus may include a urine qualitative measuring section configured to acquire a measurement result for each of a plurality of urine qualitative measurement items and a urine sediment measuring section configured to acquire a measurement result for each of a plurality of urine sediment measurement items. The apparatus may also include an operation part that can specify a combination of one of the plurality of urine qualitative measurement items and one of the plurality of urine sediment measurement items. An information processing unit may also be included.
    Type: Grant
    Filed: April 10, 2017
    Date of Patent: August 13, 2019
    Assignee: SYSMEX Corporation
    Inventors: Toru Mizumoto, Keisuke Tsutsumida, Takayoshi Izumi
  • Patent number: 10126276
    Abstract: A column protection gas supply channel (4) is connected to a channel (17) for carrier gas present between a sample vaporization chamber (12) and an MS section (2). During a standby, a column (11) may be protected on the downstream side of a merging section (16) of the column protection gas supply channel (4) and the channel (17) for carrier gas by supplying column protection gas through the column protection gas supply channel (4). At this time, there is remaining carrier gas in the channel (17) for carrier gas on the upstream side of the merging section (16). Accordingly, when carrier gas is then supplied at a time of start of an analysis, a certain amount of carrier gas is already present inside the channel (17). Therefore, the time required to completely replace the column protection gas in the channel (17) by the carrier gas is reduced, and the standby time until the start of the analysis may be reduced.
    Type: Grant
    Filed: September 25, 2013
    Date of Patent: November 13, 2018
    Assignee: SHIMADZU CORPORATION
    Inventors: Masato Takakura, Syuichi Kawana
  • Patent number: 9952239
    Abstract: The invention provides a sample inspection automation system capable of easily, reliably, and efficiently responding to requests for reinspection or addition of inspection items. The sample inspection automation system includes a storage unit having a sample replacing mechanism for transferring a sample from a tray to a sample transfer line. When the system receives sample retrieval information through the communication between an operating unit and a laboratory information system (LIS), or a host system of the sample inspection automation system, the sample is transferred to the appropriate sample treatment unit through the transfer line. Thus, when a request for reinspection or an addition inspection is issued, the sample inspection automation system can efficiently respond to it.
    Type: Grant
    Filed: July 29, 2013
    Date of Patent: April 24, 2018
    Assignee: Hitachi High-Technologies Corporation
    Inventors: Kenichi Yasuzawa, Kenichi Takahashi, Koji Kamoshida, Masashi Akutsu, Shigeru Yano
  • Patent number: 9880182
    Abstract: An automatic analysis device is provided with a reagent container disk, a reagent loader (6), a reagent loader position sensor, an RFID antenna, a memory unit, a reagent loading switch (26), and reagent load position LEDs (21-25). The reagent loader (6) has a plurality of slots for inserting reagent containers (4) and moves between the outside and the reagent container disk. The reagent load position LEDs (21-25) display determination results for each slot indicating whether the reagent accommodated in the reagent container inserted into the slot or the slot can be used on the basis of the presence of a reagent container in the slot and the reagent state of the inserted reagent or the state of the slot.
    Type: Grant
    Filed: July 8, 2014
    Date of Patent: January 30, 2018
    Assignee: Hitachi High-Technologies Corporation
    Inventors: Hiroki Fujita, Toshiharu Suzuki
  • Patent number: 9720006
    Abstract: In an automatic analyzing apparatus that analyzes a mixture of a tested sample and a reagent, by selecting the reagent, acquiring cross-check information unique to the kind of the selected reagent, inputting input information for acquiring permission for input of data including an analysis parameter of the selected reagent, and cross-checking the cross-check information and the input information, it is determined whether to permit the input of the data. In a case that it is determined to permit the input of the data, the input of the data is accepted and, based on the analysis parameter reflecting the inputted data, the mixture of the tested sample and the reagent is measured and analysis data is generated.
    Type: Grant
    Filed: September 2, 2009
    Date of Patent: August 1, 2017
    Assignee: Toshiba Medical Systems Corporation
    Inventor: Naoki Ooe
  • Patent number: 9507809
    Abstract: Systems, apparatuses, and methods can provide parameters of operating results for control products used in biological reactions. For example, automatically updated inserts containing such parameters for clinical quality controls can be provided. A customer can log into a website, provide lot number of quality control products, information about instruments, and tests being performed and then receive updated parameters for the products. The product inserts can be customized for or by a particular customer.
    Type: Grant
    Filed: June 19, 2014
    Date of Patent: November 29, 2016
    Assignee: Bio-Rad Laboratories, Inc.
    Inventors: Daniel Burdette, Phuong Le-Thi
  • Patent number: 9329166
    Abstract: A urine sample testing apparatus comprises: a urine qualitative measuring section configured to acquire a measurement result for each of a plurality of urine qualitative measurement items; a urine sediment measuring section configured to acquire a measurement result for each of a plurality of urine sediment measurement items; an operation part that is operable by a user to specify a combination of one of the plurality of urine qualitative measurement items and one of the plurality of urine sediment measurement items; an information processing unit configured to determine whether or not a first measurement result of the urine sample obtained by the urine qualitative measuring section and a second measurement result of the urine sample obtained by the urine sediment measuring section have a predetermined relationship with respect to the urine qualitative measurement item and the urine sediment measurement item included in the specified combination.
    Type: Grant
    Filed: June 18, 2014
    Date of Patent: May 3, 2016
    Assignee: Sysmex Corporation
    Inventors: Toru Mizumoto, Keisuke Tsutsumida, Takayoshi Izumi
  • Patent number: 9227190
    Abstract: The present invention is to present a sample measuring apparatus, comprising: a reagent holder for holding plural kinds of reagents; a measurement unit for measuring a measurement sample, prepared from a sample and plural kinds of reagents held by the reagent holder, for a predetermined measurement item; a display; and a display controller for controlling the display so as to display a screen including a predetermined display area showing a measurable number of times indicating how many times the measuring unit is able to perform a measurement for the predetermined measurement item by using the plural kinds of reagents held by the reagent holder.
    Type: Grant
    Filed: October 28, 2009
    Date of Patent: January 5, 2016
    Assignee: SYSMEX CORPORATION
    Inventors: Keitarou Kondou, Naohiko Matsuo
  • Patent number: 9151736
    Abstract: An apparatus (100) for measuring quality of a urea solution is operated with at least a portion of the apparatus inserted into the urea solution. The apparatus (100) includes a configuration of sensors (180, 190, 200) for measuring mechanical and electrical properties within a volume of the urea solution, the measurements of mechanical and electrical properties being mutually differently influenced by components present in the urea solution. A data processing arrangement (230) of the apparatus (100) is operable to process the measurements of mechanical and electrical properties for generating output data (120) indicative of a quality of the urea solution. The apparatus (100) is also capable of being adapted to measure qualities of other types of solution.
    Type: Grant
    Filed: December 21, 2010
    Date of Patent: October 6, 2015
    Assignee: Wema Systems AS
    Inventor: Bjørn Frivik
  • Patent number: 9086379
    Abstract: An integrated chemical separation device includes a chemical separation unit configured to separate a plurality of substances in a sample solution, a mixing chamber configured to receive the plurality of substances in the sample solution at different times, a chemical separation and detection controller, and a multi-channel valve configured to direct the plurality of substances in the sample solution to the mixing chamber under the control of the chemical separation and detection controller. The chemical separation and detection controller can introduce nano particles in the mixing chambers to allow each of the plurality of substances to be adsorbed on the nano particles. A Raman scattering spectrometer unit emits a laser beam to illuminate molecules adsorbed on the surfaces of the nano particles and obtains Raman spectra from the plurality of substances.
    Type: Grant
    Filed: September 7, 2012
    Date of Patent: July 21, 2015
    Assignee: OptoTrace (SuZhou) Technologies, Inc.
    Inventors: Xun Guo, Hong Wang
  • Patent number: 9063101
    Abstract: An analyzing system, including: a plurality of inspection lines, each including a reagent supplying apparatus, and a plurality of hematology analyzers, each analyzing a measurement sample prepared from a blood sample and a reagent supplied from the reagent supplying apparatus; and a computer connected to the reagent supplying apparatuses, wherein each reagent supplying apparatus includes a storing part adapted to store a concentrated reagent, a detector adapted to detect a weight of or liquid level in the storing part, a first controller adapted to calculate a remaining amount of the concentrated reagent from an output of the detector and to transmit the calculated amount to the computer, and wherein the computer includes a display, and a second controller adapted to receive the amount data transmitted from the reagent supplying apparatuses, to generate display data integrating the plurality of received amount data and to show the display data on the display.
    Type: Grant
    Filed: March 21, 2011
    Date of Patent: June 23, 2015
    Assignee: Sysmex Corporation
    Inventors: Hiroyuki Tanaka, Hiroyoshi Nishio
  • Patent number: 9040304
    Abstract: A multi-channel system and methods for sorting particles according to one or more characteristics of the particles. The system includes multiple flow cytometry units, each unit can have a nozzle for producing a fluid stream containing a desired population of particles in a mixture of particles. Each of the units may be operable to sort said desired population of particles by interrogating the fluid stream with a beam of electromagnetic radiation and classifying particles based on one or more characteristics of the particles. The system also includes a common fluid delivery system for delivering sheath fluid to each flow cytometer unit for producing respective fluid streams.
    Type: Grant
    Filed: March 12, 2014
    Date of Patent: May 26, 2015
    Assignee: Inguran, LLC
    Inventors: Gary Durack, Jeffrey D. Wallace, Gary P. Vandre, Lon A. Westfall, Jeremy T. Hatcher, Niraj V. Nayak
  • Publication number: 20150140668
    Abstract: An automation system for an in vitro diagnostics environment includes a plurality of intelligent carriers that include onboard processing and navigation capabilities. The intelligent carriers can include one or more image sensors to observe the relative motion of the track as the carrier traverses it. The carriers can also observe position marks on the track surface to provide absolute position information, which can include additional data, such as routing instructions. Synchronization marks may be provided to correct errors in the observed trajectory.
    Type: Application
    Filed: May 21, 2013
    Publication date: May 21, 2015
    Applicant: Siemens Healthcare Diagnostics Inc.
    Inventors: Colin Mellars, Baris Yagci, Benjamin Samuel Pollack
  • Publication number: 20150111300
    Abstract: A clinical laboratory apparatus includes a pretreating apparatus having a high separation capability and providing high data reproducibility and reliability and a mass spectrometer is provided which executes fully automatic processing from pretreatment to detection. The pretreating apparatus that includes a cartridge for holding an extraction agent for solid-phase extraction, a pressure-loading unit for applying a pressure load to any cartridge mounted on the solid-phase extraction cartridge-retaining unit, a receiving tray mechanism for receiving a sample extracted from the cartridge, and a liquid-level sensor for detecting liquid levels in the receiving tray as well as in the cartridge, conducts feedback control for the pressure-loading unit to open its pressure release valve upon the liquid-level sensor detecting that the liquid level in the receiving tray mechanism has reached a preset liquid-level position.
    Type: Application
    Filed: December 22, 2014
    Publication date: April 23, 2015
    Inventors: Makoto NOGAMI, Katsuhiro KANDA, Izumi WAKI
  • Patent number: 9005980
    Abstract: A method including automatically displaying information obtained from a first identifier associated with a slide and a second identifier associated with a reagent cartridge. The method further including generating a staining log based on the information obtained from the first identifier and the second identifier. A further method includes displaying a location of a slide within a sample processing system and information obtained from a first identifier associated with the slide in a first table and displaying a location of a reagent cartridge within a sample processing system and information obtained from a second identifier associated with the reagent cartridge in a second table. The first table is then aligned with the second table.
    Type: Grant
    Filed: October 18, 2013
    Date of Patent: April 14, 2015
    Assignee: Sakura Finetek U.S.A., Inc.
    Inventors: Robert E. Evans, Anthony L. Hartman, Richard A. Suchter, Gilles Lefebvre
  • Patent number: 8999240
    Abstract: An automatic analyzer and an automatic analyzing system to identify samples and reagents used in the analyzer and members used in measurement of at least two objects in common: system reagents or buffer solution; sensor parts; probes; nozzles; chips; dispensing cups; tubes; ISE electrodes; detectors; deionized water; and waste, and to unify management of identification information thereof and a measurement result.
    Type: Grant
    Filed: July 11, 2012
    Date of Patent: April 7, 2015
    Assignee: Hitachi High-Technologies Corporation
    Inventors: Noriko Maeda, Kyoko Imai, Taku Sakazume, Yukie Tokiwa, Kantaro Suzuki
  • Patent number: 8999139
    Abstract: Oxidation/reduction measurement is described. An aspect provides an oxidation/reduction quantification method, including: receiving intermittent oxidizer/reducer reference measurements from one or more reference sensors; receiving one or more substantially continuous oxidizer/reducer-related measurements from one or more corroboration sensors; and processing the one or more substantially continuous oxidizer/reducer-related measurements with the intermittent oxidizer/reducer reference measurements to generate substantially continuous representative oxidizer/reducer measurements. Other aspects are described.
    Type: Grant
    Filed: April 30, 2012
    Date of Patent: April 7, 2015
    Assignee: Hach Company
    Inventors: Vadim B. Malkov, David Langley Rick
  • Publication number: 20150093754
    Abstract: Disclosed is an analyzer comprising: a liquid container mounting section in which a liquid container are set; a container mounting section in which at least one tip container accommodating a plurality of pipette tips is set; a cover detecting section that detects a presence of a cover mounted on the tip container; a dispensing section that equips a pipette tip accommodated in the tip container and dispenses a quantity of liquid from the liquid container to a reaction container via the equipped pipette tip; a detecting section that interrogate a property of the liquid; and a controller programmed to prohibit a process of equipping the pipette tip by the dispensing section when the cover on the tip container is detected, and permits the process when no cover is detected.
    Type: Application
    Filed: September 25, 2014
    Publication date: April 2, 2015
    Inventors: Kazuki ASAO, Tsukasa HIRATA
  • Patent number: 8980636
    Abstract: A system and method for performing automated titrations. An automatic titrator utilizes control devices and sensors adapted for various chemical reactions to perform titrations and determine the content of a desired component of a solution. Batch and continuous mode titrations are possible. Titrant is added to a sample either in varying amounts or rates and a titration endpoint is observed via sensors. Control devices detect when the titration endpoint occurs and calculates the desired content. Various reactions within the solution may be suppressed in order to titrate isolated components individually.
    Type: Grant
    Filed: March 15, 2013
    Date of Patent: March 17, 2015
    Assignee: Ecolab USA Inc.
    Inventors: John Wilhelm Bolduc, Blake Roberts Otting, Paul R. Kraus, Robert Ryther
  • Patent number: 8956875
    Abstract: Provided are automated methods for measuring soluble magnesium concentration in water using fluorescence. The methods employ the use of a pH-buffered liquid and a magnesium coordinating fluorescing reagent. In certain embodiments, the methods may further employ measuring total hardness concentration of the water by displacing any soluble calcium with soluble magnesium and then re-measuring the soluble magnesium concentration. Optionally, the soluble calcium concentration can be determined by subtracting the measured soluble magnesium concentration from the measured total hardness concentration.
    Type: Grant
    Filed: March 14, 2013
    Date of Patent: February 17, 2015
    Assignee: Ecolab USA, Inc.
    Inventors: Arthur J. Kahaian, Alexandra Knoth, Hui Li, Rodney H. Banks, Joe L. Schwartz, Sascha J. Welz
  • Publication number: 20150044664
    Abstract: A temperature control device and method are provided for an analytical system for performing laboratory protocols. The device includes a well within a housing configured to receive a biological specimen according to a predetermined sample process. The specimen is suspended by a holding device in the well. A thermal element is provided in heat exchange communication with fluid in the well. A temperature sensor is located in the well at a location to be covered and uncovered by rocking motion of fluid in the well. A controller, in communication with the thermal element, the temperature sensor, and an agitation system, is operative to control the thermal element in correlation with temperature data, for example, peak temperature data, from the temperature sensor.
    Type: Application
    Filed: March 8, 2013
    Publication date: February 12, 2015
    Inventors: Kevin J. Sullivan, James Kelland, Nhat Khai L. Nguyen
  • Patent number: 8951480
    Abstract: A modular chemical production system includes multiple modules for performing a chemical reaction, particularly of radiochemical compounds, from a remote location. One embodiment comprises a reaction vessel including a moveable heat source with the position thereof relative to the reaction vessel being controllable from a remote position. Alternatively the heat source may be fixed in location and the reaction vial is moveable into and out of the heat source. The reaction vessel has one or more sealing plugs, the positioning of which in relationship to the reaction vessel is controllable from a remote position. Also the one or more reaction vessel sealing plugs can include one or more conduits there through for delivery of reactants, gases at atmospheric or an elevated pressure, inert gases, drawing a vacuum and removal of reaction end products to and from the reaction vial, the reaction vial with sealing plug in position being operable at elevated pressures.
    Type: Grant
    Filed: August 19, 2009
    Date of Patent: February 10, 2015
    Assignee: The Regents of the University of California
    Inventors: Nagichettiar Satyamurthy, Jorge R. Barrio, Bernard Amarasekera, R. Michael Van Dam, Sebastian Olma, Dirk Williams, Mark A. Eddings, Clifton Kwang-Fu Shen
  • Patent number: 8945470
    Abstract: The present invention is to present a sample analyzer comprising: a first measurement unit; a second measurement unit; a transport unit for transporting a sample container to the first measurement unit and the second measurement unit; and a controller configured to perform operations comprising: obtaining measurement item information indicating a measurement item of the sample contained in the sample container; and controlling the transport unit so as to transport the sample container to the second measurement unit when a first measurement item and a second measurement item different from the first measurement item are indicated in the measurement item information, and controlling the transport unit so as to transport the sample container to the first measurement unit or the second measurement unit when the first measurement item is indicated and the second measurement item is not indicated in the measurement item information.
    Type: Grant
    Filed: March 31, 2010
    Date of Patent: February 3, 2015
    Assignee: Sysmex Corporation
    Inventors: Keisuke Kuwano, Daigo Fukuma
  • Publication number: 20150031136
    Abstract: A test apparatus, which may compare detection data of a detector with reference data and correct a positional error in the detector due to the failing of a motor, and a method of controlling the same are provided. The test apparatus includes a detector configured to irradiate light to a plurality of chambers of a reaction device and detect a detection target, a motor configured to move the detector such that light is irradiated to the plurality of chambers, and a controller configured to compare detection data of the detector regarding the reaction device with reference data, determine a positional error in the detector, and correct the positional error.
    Type: Application
    Filed: April 11, 2014
    Publication date: January 29, 2015
    Applicant: SAMSUNG ELECTRONICS CO., LTD.
    Inventors: Se Do GWON, Kyu Tae KANG
  • Patent number: 8926903
    Abstract: To perform accurate measurement in the analysis of chemical components with low concentration, pretreatment such as concentration and purification of samples is essential. For high-throughput of pretreatment of biological samples, various random clinical testing is encountered, where analytes change from sample to sample. The pretreatment apparatus has a separating agent selectively separating a specific component by allowing a sample solution to flow therethrough. A holding section holds a plurality of housing sections, which house the separating agent therein, and has an endless track. A pressurizing section applies pressure to the housing section in a continuous and random-accessible manner; and an extraction solution receiver mechanism selectively receives an extracted solution from the separating agent housed in the housing section. A mass spectrometer is that can be connected to the pretreatment apparatus. Thus, a large number of specimens can be simultaneously processed.
    Type: Grant
    Filed: July 8, 2009
    Date of Patent: January 6, 2015
    Assignee: Hitachi High-Technologies Corporation
    Inventors: Makoto Nogami, Katsuhiro Kanda, Izumi Waki
  • Patent number: 8922646
    Abstract: A method of calculating a drop delay in a stream of a flow cytometer. In one embodiment the method includes the steps of determining a widths plot by measuring the width of a stream based on an image of the stream and setting drop delay based on the widths plot. In another aspect the invention relates to a flow cytometer system for automatically calculating drop delay. In one embodiment the flow cytometer system includes means for determining a widths plot based on an image of the stream; and means for calculating drop delay based on the widths plot.
    Type: Grant
    Filed: March 9, 2011
    Date of Patent: December 30, 2014
    Assignee: Beckman Coulter, Inc.
    Inventors: David Neckels, Kevin Courter
  • Patent number: 8918217
    Abstract: A reverse osmosis separation process is disclosed, such as for desalination and waste water reuse process, wherein an effectiveness of membrane cleaning can be estimated. Exemplary embodiments operate the reverse osmosis membrane cleaning process for a controlled time for cleaning and with a controlled value of chemical concentration in a chemical liquor prepared for cleaning the membrane. A method can include estimating fouling status of the membrane and determining a controlled value of chemical concentration in the chemical liquor, and a controlled time for cleaning based on the fouling status of the membrane.
    Type: Grant
    Filed: October 18, 2012
    Date of Patent: December 23, 2014
    Assignee: ABB Research Ltd.
    Inventors: Senthilmurugan Subbiah, Mekapati Srinivas, Naveen Bhutani
  • Patent number: 8916097
    Abstract: A controller for an automated immunoassay system is provided to manage the system resources and control the flow of samples under test. The controller allows tests to be run dynamically instead of in a serial, first in first out flow. The controller evaluates the set of tests to be run and generates a sequencing strategy. The sequencing strategy is based on the paths specified for each type of assay, the numbers of tests to be run, the priority of each test and the resources required for each test. In addition, the controller can resolve resource allocation conflicts and modify the sequencing strategy as test conditions change during operation.
    Type: Grant
    Filed: March 31, 2004
    Date of Patent: December 23, 2014
    Assignee: Siemens Healthcare Diagnostics Inc.
    Inventors: David Stein, Marcel J. Goetz, Jr., Sanchoy Das
  • Publication number: 20140370609
    Abstract: The invention provides for an analysis system (100, 300, 400) for analyzing a biological sample (108) comprising an analyzer (102) with an analytical unit (106) for analyzing the biological sample to obtain an analysis result (140). The analyzer is configured for receiving a cartridge (110) comprising an identifier (114) and containing at least one reagent for analyzing the biological sample. The analyzer comprises an identification unit (116) for reading the identifier. The analyzer accepts the cartridge if the identifier is valid. The analysis system further comprises a protocol creation system (150, 104).
    Type: Application
    Filed: April 3, 2014
    Publication date: December 18, 2014
    Applicant: Roche Molecular Systems, Inc.
    Inventors: Paul Frank, Christopher Newhouse, Sascha Roehrig
  • Patent number: 8900877
    Abstract: A parallel processing system for processing samples is described. In one embodiment, the parallel processing system includes an instrument interface parallel controller to control a tray motor driving system, a close-loop heater control and detection system, a magnetic particle transfer system, a reagent release system, a reagent pre-mix pumping system and a wash buffer pumping system.
    Type: Grant
    Filed: April 30, 2012
    Date of Patent: December 2, 2014
    Assignee: Luminex Corporation
    Inventors: Steve Jia Chang Yu, Jesus Ching, Phillip You Fai Lee, David Hsiang Hu
  • Patent number: 8894930
    Abstract: A specimen processing device is disclosed that comprises: a processing unit configured to aspirate a specimen from a specimen container accommodating the specimen, and to process the aspirated specimen; a state transition section configured to make the processing unit undergo transition to a pause state; an instruction accepting section configured to accept an instruction to start processing of the specimen when the processing unit is in the pause state; and a pause state releasing section configured to release the processing unit from the pause state to make the processing unit perform the processing of specimen when the instruction to start the processing is accepted by the instruction accepting section. A specimen processing method using a specimen processing device is also disclosed.
    Type: Grant
    Filed: May 26, 2010
    Date of Patent: November 25, 2014
    Assignee: Sysmex Corporation
    Inventor: Toru Mizumoto
  • Patent number: 8865473
    Abstract: A luminescence detecting apparatus and method for analyzing luminescent samples is disclosed. A detecting apparatus may be configured so that light from luminescent samples pass through a collimator, a first lens, a filter, and a camera lens, whereupon an image is created by the optics on the charge-coupled device (CCD) camera. The detecting apparatus may further include central processing control of all operations, multiple wavelength filter wheel, and/or a robot for handling of samples and reagents.
    Type: Grant
    Filed: August 13, 2012
    Date of Patent: October 21, 2014
    Assignee: Applied Biosystems, LLC
    Inventors: Michael Gambini, Jeff Levi, John Voyta, Bruce E. DeSimas, II, Edward Lakatos, Israel Metal, George Sabak, Yongdong Wang, Susan A. Atwood-Stone
  • Publication number: 20140273243
    Abstract: Provided are automated methods for measuring soluble magnesium concentration in water using fluorescence. The methods employ the use of a pH-buffered liquid and a magnesium coordinating fluorescing reagent. In certain embodiments, the methods may further employ measuring total hardness concentration of the water by displacing any soluble calcium with soluble magnesium and then re-measuring the soluble magnesium concentration. Optionally, the soluble calcium concentration can be determined by subtracting the measured soluble magnesium concentration from the measured total hardness concentration.
    Type: Application
    Filed: March 14, 2013
    Publication date: September 18, 2014
    Applicant: ECOLAB USA INC.
    Inventors: Arthur J. Kahaian, Alexandra Knoth, Hui Li, Rodney H. Banks, Joe L. Schwartz, Sascha J. Welz
  • Patent number: 8834796
    Abstract: A chromatographic optical detection system includes an optical detector disposed to receive light scattered from a stream of particles and configured to convert the received light to an electrical signal; a signal-processing unit in signal communication with the optical detector to receive the electrical signal, and configured to convert the electrical signal to digital pulses and count the digital pulses to output a first signal corresponding to a number of particles detected in a time interval, and configured to integrate and digitize the electrical signal to output a second signal corresponding to the number of particles detected in the time interval; and a data station in signal communication with the signal-processing unit, and configured to select the first signal, if the number of particles detected in the time interval is less than a threshold criterion, and to select the second signal if the number of particles detected in the time interval exceeds the threshold criterion.
    Type: Grant
    Filed: April 5, 2013
    Date of Patent: September 16, 2014
    Assignee: Waters Technologies Corporation
    Inventor: Joseph A. Jarrell
  • Patent number: 8828728
    Abstract: An aquatic environment monitoring system and method that includes correction for adverse conditions in the monitoring system involving the development of confidence levels for certain conditions in the monitoring system using stored information related to the aquatic environment and/or the monitoring system. Corrections to adverse conditions may be made by the environment monitoring system automatically by the monitoring system and manually via communications to a user of the system.
    Type: Grant
    Filed: December 13, 2012
    Date of Patent: September 9, 2014
    Assignee: Step Ahead Innovations, Inc.
    Inventor: James E. Clark
  • Patent number: 8815601
    Abstract: A calorimeter with at least one reactor for receiving a sample is disclosed. A reactor jacket may surround the reactor. A reactor-heating device and a reactor-cooling device serve to regulate an internal reactor temperature. The reactor-cooling device preferably comprises a thermoelectric cooling element that is thermally connected to a coolant. The reactor-cooling device and the reactor-heating device are preferably individual units, both of which are thermally connected to the reactor by way of the reactor jacket. A temperature control device is provided to control the reactor-heating device and the reactor-cooling device.
    Type: Grant
    Filed: April 26, 2010
    Date of Patent: August 26, 2014
    Assignee: Mettler-Toledo AG
    Inventor: Benedikt Schenker
  • Patent number: 8805586
    Abstract: The present invention relates to a system for optimizing and controlling the particle size distribution and scale-up of production of nanoparticle in an aerosol flame reactor. The method provides nanoparticles with desired, optimized and controlled particle size and the specific surface area in aerosol reactors using a simulation tool with programmed instructions. The simulation tool couples flame dynamics model and particle population balance model.
    Type: Grant
    Filed: July 11, 2011
    Date of Patent: August 12, 2014
    Assignee: Tata Consultancy Services Limited
    Inventors: Venkataramana Runkana, Venkata Sudheendra Buddhiraju, Nagaravi Kumar Varma Nadimpalli
  • Publication number: 20140206087
    Abstract: A temperature control device which may control temperature of a reactor, and a test apparatus including the same are provided. The temperature control device includes at least one body, temperature controllers provided on the at least one body and configured to control a temperature of the at least one body, and at least one temperature sensor provided on the at least one body and configured to measure the temperature of the at least one body.
    Type: Application
    Filed: January 24, 2014
    Publication date: July 24, 2014
    Applicant: SAMSUNG ELECTRONICS CO., LTD.
    Inventor: Joo Young OH
  • Patent number: 8778686
    Abstract: Provided are an automatic analyzer which moves a dispensing apparatus having a dispensing probe, or a vessel by a driving mechanism to dispense plural liquids into the vessel via the dispensing probe, and measures and analyzes optical characteristic of a reaction liquid in which each of the dispensed liquids is reacted, and a dispensing method thereof. The automatic analyzer includes a drive controlling unit which controls the driving mechanism so that the liquid surface of the liquid and a distal end of the dispensing probe are moved relatively to each other in a vertical direction, and, when the liquids including precipitated substance are to be dispensed, the dispensing probe sucks in the liquids from plural different positions along the vertical direction.
    Type: Grant
    Filed: December 29, 2008
    Date of Patent: July 15, 2014
    Assignee: Beckman Coulter, Inc.
    Inventor: Akihisa Kuroda
  • Publication number: 20140193918
    Abstract: An automatic analyzer adapted to enhance sample/reagent dispensing accuracy, regardless of a difference in sample/reagent dispensing height of a dispensing probe. When the amount of sample in a sample container is small, tip height “h1” of a sample dispensing probe positioned immediately after it has aspirated the sample decreases below tip height “h?” of the sample dispensing probe positioned immediately before it discharges the sample. The sample in this state takes a concave shape at the tip of the sample dispensing probe positioned immediately before it discharges the sample. When the amount of sample in a sample container is large, tip height “h2” of the sample dispensing probe positioned immediately after it has aspirated the sample increases above the tip height “h?” and the sample takes a convex shape at the tip of the sample dispensing probe positioned immediately before it discharges the sample.
    Type: Application
    Filed: July 19, 2012
    Publication date: July 10, 2014
    Applicant: HITACHI HIGH-TECHNOLOGIES CORPORATION
    Inventors: Kenichi Takahashi, Isao Yamazaki
  • Patent number: 8772037
    Abstract: In an analysis system having an analysis apparatus using a reagent container having a memory to store reagent information concerning the reagent in the reagent container and a remote computer, the following steps are executed: reading out the reagent information from the memory of the reagent container; judging, based on the read reagent information, whether or not the reagent in the reagent container is usable; when it is judged that the reagent in the reagent container is unusable, writing data representing the reagent is unusable into the memory of the reagent container; and when it is judged that the reagent in the reagent container is unusable, registering the data representing the reagent is unusable, into a reagent database managed by the remote computer in association with identification information to identify the reagent container. Thus, it is possible to automatically identify the reagent, which should not be used, and to manage the reagent not so as to use it for the analysis.
    Type: Grant
    Filed: July 22, 2005
    Date of Patent: July 8, 2014
    Assignee: Wako Pure Chemical Industries, Ltd.
    Inventors: Masahiro Satomura, Hishiri Komiyama
  • Patent number: 8765474
    Abstract: An automatic analyzer which assures uniformity in mixing effects regardless of sample quantity and test item and thus produces analysis results with high repeatability. The automatic analyzer includes a device for adding a conditioning liquid into a reaction chamber so that the quantity of liquid in the reaction chamber becomes a predetermined quantity prior to being mixed. The conditioning liquid may be a diluent or physiological saline as used for dilution of a sample or any other special liquid that adjusts the properties such as viscosity, surface tension, etc. of liquid to be mixed.
    Type: Grant
    Filed: February 15, 2008
    Date of Patent: July 1, 2014
    Assignee: Hitachi High-Technologies Corporation
    Inventors: Katsuhiro Kambara, Shigenori Watari, Hidetoshi Sugiyama
  • Patent number: 8765475
    Abstract: Various embodiments disclose a colorimetric absorbance measurement method and a system for performing the same. The method comprises driving a reaction tray carrying a plurality of reaction cuvettes to rotate at a speed; transferring or rotating filters on a filter wheel to a light path of a light beam, starting from a filter of a first wavelength; and sampling photoelectric data when the light beam has passed through each reaction cuvette in some embodiments. The method ensures consistency in the measurement and synchronization between the calibration and the sample test and reliability of the measurements. Various embodiments simplify data processing and reduce the complexity of the system.
    Type: Grant
    Filed: October 23, 2008
    Date of Patent: July 1, 2014
    Assignee: Shenzhen Mindray Bio-Medical Eletronics Co., Ltd.
    Inventors: Lihua Zhou, Zhihong Wang, Yanwen Weng, Feng Li
  • Patent number: 8758685
    Abstract: An automatic analyzer is free from limitations on layout of various mechanisms, and thus causing no bottlenecks, for example, in a space-saving design of the automatic analyzer. This invention includes a coaxial planar duplex arrangement of two dilution disks each with annularly disposed dilution cells, and the dilution disks A and B operate independently of each other. Various mechanisms (parent-sample sampling mechanism, diluent delivery mechanism, diluent/sample mixing mechanism, and diluted-sample sampling mechanism) used in a dilution process can each access the two dilution disks. The dilution process for a parent sample, executed on the dilution disks A and B, can be continuously conducted by providing a fixed delay in operational timing between the two dilution disks.
    Type: Grant
    Filed: September 9, 2008
    Date of Patent: June 24, 2014
    Assignee: Hitachi High-Technologies Corporation
    Inventors: Hidenobu Komatsu, Tetsuya Fujisawa
  • Patent number: 8759106
    Abstract: A clinical tester has been described that includes a probe to aspirate a fluid. The probe is washed between aspirations to reduce carryover. The wash operation includes both an internal and an external wash, where the internal wash operation is terminated prior to terminating the external wash. In one embodiment, the probe wash can be implemented on an integrated clinical chemistry/immunoassay tester.
    Type: Grant
    Filed: March 1, 2010
    Date of Patent: June 24, 2014
    Assignee: Abbott Laboratories
    Inventors: Patricia H. Ravalico, Charlie W. Wilson, III
  • Patent number: 8753309
    Abstract: Devices, systems, or methods are disclosed herein for treatment of disease in a vertebrate subject. The device can include a quasi-planar substrate; and one or more laterally-mobile effector molecule types at least partially embedded within the quasi-planar substrate, wherein the one or more laterally-mobile effector molecule types is configured to interact with one or more cell types. The device can further include one or more sensors configured to detect at least one aspect of an interaction between the at least one of the one or more laterally-mobile effector molecule types and the one or more cell types; and a controller in communication with the one or more sensors, wherein the controller is configured to responsively initiate modification of at least one of the one or more laterally-mobile effector molecule types, the quasi-planar substrate, and the one or more cell types.
    Type: Grant
    Filed: June 24, 2011
    Date of Patent: June 17, 2014
    Assignee: The Invention Science Fund I, LLC
    Inventors: Roderick A. Hyde, Lowell L. Wood, Jr.
  • Patent number: 8753572
    Abstract: Stepped portions of a flow channel are reduced by completely fixing the channel that extends to the measuring unit, and reducing connections in the channel, thereby to suppress a disturbance in the flow of the liquid suctioned into the measuring unit. A means is provided so that the reaction solution and reagent suctioned will move towards the channel through which the liquids are suctioned.
    Type: Grant
    Filed: January 18, 2010
    Date of Patent: June 17, 2014
    Assignee: Hitachi High-Technologies Corporation
    Inventors: Susumu Sakairi, Taku Sakazume, Katsuaki Takahashi
  • Patent number: 8747347
    Abstract: Devices, systems, or methods are disclosed herein for treatment of disease in a vertebrate subject. The device can include a quasi-planar substrate; and one or more laterally-mobile effector molecule types at least partially embedded within the quasi-planar substrate, wherein the one or more laterally-mobile effector molecule types is configured to interact with one or more cell types. The device can further include one or more sensors configured to detect at least one aspect of an interaction between the at least one of the one or more laterally-mobile effector molecule types and the one or more cell types; and a controller in communication with the one or more sensors, wherein the controller is configured to responsively initiate modification of at least one of the one or more laterally-mobile effector molecule types, the quasi-planar substrate, and the one or more cell types.
    Type: Grant
    Filed: September 23, 2011
    Date of Patent: June 10, 2014
    Assignee: The Invention Science Fund I, LLC
    Inventors: Roderick A. Hyde, Lowell L. Wood, Jr.
  • Patent number: 8741229
    Abstract: The present invention is to present a sample analyzer, comprising: a reagent holder for holding a first and a second reagents; a display; a display controller for controlling the display so as to display a display screen including a first information displaying region for displaying one of a plurality of reagent information regarding the first reagent and a second information displaying region for displaying one of a plurality of reagent information regarding the second reagent; and a display switch receiver for receiving a display switch instruction of reagent information displayed in each of the first and second information displaying regions, wherein the display controller switches a first reagent information displayed in the first information displaying region to a second reagent information and switches a third reagent information displayed in the second information displaying region to a fourth reagent information, when the display switch receiver has received the display switch instruction.
    Type: Grant
    Filed: October 28, 2009
    Date of Patent: June 3, 2014
    Assignee: Sysmex Corporation
    Inventor: Keitarou Kondou
  • Patent number: 8716025
    Abstract: A control device for a sample separation apparatus, the sample separation apparatus including a first separation unit and a second separation unit downstream of the first separation unit and supplied with the fluidic sample after treatment by the first separation unit. A control device is configured for controlling the first separation unit to execute a primary separation sequence within a time interval for separating the fluidic sample into fractions, and for controlling the second separation unit to execute secondary separation sequences within the time interval for further separating the separated fractions into sub-fractions, wherein the secondary separation sequences form part of a common sample separation method defined by a common specification of the sample separation involving a set of parameters, and adjusting, over a progress of the primary separation sequence, at least one parameter according to which at least one of the plurality of secondary separation sequences is executed.
    Type: Grant
    Filed: July 8, 2011
    Date of Patent: May 6, 2014
    Assignee: Agilent Technologies, Inc.
    Inventor: Klaus Witt