For Medical Or Dental Instruments Or Equipment (e.g., Electronic Hematological Analyzer, Etc.) Patents (Class 510/161)
  • Patent number: 10299473
    Abstract: The present invention relates to phenol containing disinfectants that have superior broad-spectrum antimicrobial efficacy versus traditional chemistry such as quaternary ammonium-containing disinfectants or aliphatic alcohols. Hydrotropic surfactants are utilized in combination with generally environmentally friendly phenol containing compounds such as ortho-benzyl parachlorophenol (OBPCP), ortho phenylphenol (OPP), or parachloro-meta-cresol (PCMC) in the presence of suitable solvents such as an aliphatic alcohol and also in the presence of an inorganic acid, such as phosphoric acid. The solutions are free of para tertiary amylphenol (PTAP), have a low pH and are very stable with respect to gamma irradiation. They can be used with respect to hard surface disinfection, and also as a tuberculocide, a fungicide, a bactericide, and a virucide.
    Type: Grant
    Filed: February 28, 2018
    Date of Patent: May 28, 2019
    Assignee: American Sterilizer Company
    Inventors: Christopher C. Heisig, Nancy-Hope E. Kaiser, Thomas W. Smith
  • Patent number: 10194657
    Abstract: Antimicrobial compositions providing synergistic antimicrobial effects against a variety of bacterial, viral and fungal organisms are described. Methods for using the antimicrobial compositions and products containing the antimicrobial compositions are also described herein.
    Type: Grant
    Filed: September 19, 2014
    Date of Patent: February 5, 2019
    Inventors: Joseph Paul Thomas, Zsolt Istvan Hertelendy, Michael Lisle Howell
  • Patent number: 9581583
    Abstract: A blood analysis apparatus configured such that a nozzle sucks a predetermined amount of a blood specimen in a specimen container, and dispenses the specimen to each blood cell counting part which obtains count data, and a control part processes the count data to perform blood analysis. In this apparatus, two or more blood cell counting parts (basophil counting part, LMNE counting part, red blood cell counting part, white blood cell counting part) are constituted to obtain the count data of the same particular blood cell type (white blood cells), and the control part calculates the ratio or number of the existing blood cell from each count data, and judges whether the amount of the blood specimen sucked in the nozzle is normal or insufficient by comparing respective calculation results to determine whether they are within the predetermined allowable ranges.
    Type: Grant
    Filed: May 15, 2014
    Date of Patent: February 28, 2017
    Assignee: HORIBA, Ltd.
    Inventor: Yuki Ishii
  • Patent number: 9353334
    Abstract: The present invention discloses the method for cleaning a medical instrument using a treatment liquid, wherein the treatment liquid contains: (A) an alkanolamine in an amount of 0.004 to 1% by mass, (B) a nonionic surfactant in an amount of 0.002 to 1% by mass, (C) a polyhydric alcohol in an amount of 0.004 to 10% by mass, (D) an alkaline protease in an effective amount, and (E) water, and has a pH of not lower than 9.
    Type: Grant
    Filed: December 28, 2010
    Date of Patent: May 31, 2016
    Assignee: KAO CORPORATION
    Inventors: Kazuo Isobe, Masaya Nishio, Tatsuya Sakai
  • Patent number: 9091677
    Abstract: The present invention discloses multi-purpose metering fluid/rinse reagents for use in automated cellular analyzers that use liquid volumetric metering. The compositions contain a chelating agent, an ionizing salt, optionally a stabilizing ion, a buffer, a non-hemolytic surfactant, and optionally an antimicrobial agent. Advantageously, the compositions produce less than one part-per-million of formaldehyde over the course of one year. Methods for using the compositions are also described.
    Type: Grant
    Filed: August 9, 2010
    Date of Patent: July 28, 2015
    Assignee: Beckman Coulter, Inc.
    Inventors: Wayne Goldson, Sandra Socarras
  • Publication number: 20150147802
    Abstract: The present invention relates to [1] a detergent composition for a washer for medical devices, including a nonionic surfactant (A) represented by the following formula (1), at least one compound (B) selected from the group consisting of fatty acids having not less than 6 and not more than 10 carbon atoms or salts thereof, a cationic surfactant (C) represented by the specific formula, and water; and [2] a method of washing a medical device using a washer for medical devices which includes the step of washing the medical device with a mixture including the above detergent composition and an enzyme.
    Type: Application
    Filed: May 28, 2013
    Publication date: May 28, 2015
    Applicant: KAO CORPORATION
    Inventor: Masaya Nishio
  • Patent number: 9023778
    Abstract: Liquid compositions for cleaning, in particular medical instruments and air conditioning surfaces, said composition excluding surfactants and comprising one or more enzymes including a protease and optionally a hydrolase, a solvent system including a water soluble glycol ether solvent, at least one anionic hydrotrope, and wherein the molar ratio of said at least one hydrotrope to said glycol ether in the composition is selected to preserve the activity of said one or more enzymes. The hydrotrope is advantageously an anionic hydrotrope selected from the group consisting of water soluble anionic hydrotropes of the formula (I) and having no alkyl side chain greater than six carbons in length, for example a xylene sulfonate or cumene sulfonate salt.
    Type: Grant
    Filed: July 18, 2007
    Date of Patent: May 5, 2015
    Assignee: Novapharm Research (Australia) Pty Ltd.
    Inventors: Steven Kritzler, Alex Sava
  • Publication number: 20150111803
    Abstract: A cleaning composition comprises A) a fatty alcohol-alkylene oxide copolymer, B) a glycoside, and C) a benzene sulfonate, wherein, the weight ratio of the component B and the component C is less than or equal to 5:1. The cleaning composition can be used as a detergent for cleaning medical appliances.
    Type: Application
    Filed: May 24, 2012
    Publication date: April 23, 2015
    Inventors: Zhilan Liu, Ting Liu, Ying Wei Xie, Kai Qiu
  • Patent number: 8933008
    Abstract: A disinfectant solution comprising: an aldehyde; a polyol; one or more acetal derivatives formed by reaction of said aldehyde with said polyol; one or more surfactants selected from the general classes anionic, cationic, or non-ionic; one or more pH buffering agents selected from the group consisting of monosodium phosphate, disodium phosphate, trisodium phosphate, sodium tetraborate, sodium bicarbonate, sodium citrate, phosphoric acid, boric acid and citric acid. The invention also relates to a process of producing the disinfectant solution, and a method of disinfecting and/or sterilizing heat sensitive medical devices comprising treating the medical devices with the disinfectant solution of the invention.
    Type: Grant
    Filed: April 27, 2011
    Date of Patent: January 13, 2015
    Assignee: Whiteley Corporation Pty. Ltd.
    Inventors: Gregory Stuart Whiteley, Reginald Keith Whiteley, Graeme David Probert, Trevor Owen Glasbey
  • Publication number: 20150011452
    Abstract: Described are compositions and methods for the removal of zinc-oxide eugenol-based temporary cements or root canal filling materials from a variety of surfaces including surfaces inside the oral cavity, such as teeth, as well as surfaces of objects located outside of the oral cavity, such as instruments and prostheses. In certain compositions, the resin-dentin bond between permanent cements and collagen-containing surfaces can be increased. The compositions are non-toxic, can be used inside the oral cavity, and do not require special disposal procedures.
    Type: Application
    Filed: June 10, 2014
    Publication date: January 8, 2015
    Inventors: Jason Guzman, Jeffrey Wan
  • Patent number: 8920715
    Abstract: An antimicrobial solution for disinfecting instruments in an automatic sterilization device, the solution comprising: a peracid reaction product formed in situ from combining a liquid acetyl donor with a solid source of peroxide, wherein the in situ reaction takes place in the sterilization device, along with a containment and delivery ampule for use in an automatic sterilization device, and methods for disinfecting a medical instrument employing the inventive antibacterial solution.
    Type: Grant
    Filed: August 7, 2006
    Date of Patent: December 30, 2014
    Assignee: Hemostasis, LLC
    Inventors: Keith Allen Roberts, Carl William Hahn, Gabriel P. Kern, Ryan A. Hoitink, Robert Orvin Crowder, John Henry Burban
  • Patent number: 8921294
    Abstract: The present invention relates to a cleaning fluid, in particular a cleaning fluid for cleaning surfaces.
    Type: Grant
    Filed: December 16, 2011
    Date of Patent: December 30, 2014
    Inventor: Navjeet Kaur Matharu
  • Patent number: 8921295
    Abstract: A biodegradable concentrated neutral detergent composition comprises various chelate compounds, various corrosion inhibitors, an alkaline compound, at least one sequestrant, various surfactants and hydrotropes, and water. The detergent can be highly concentrated, has a good long term shelf life, and when diluted is very effective in cleaning metals such as surgical instruments and prevents corrosion resistance of the metal even in a hard water environment.
    Type: Grant
    Filed: June 29, 2011
    Date of Patent: December 30, 2014
    Assignee: American Sterilizer Company
    Inventors: Ann Maria Kneipp, Nancy-Hope E. Kaiser, Althea Noel Johnson
  • Patent number: 8888926
    Abstract: A medical instrument cleaning concentrate and method for cleaning medical equipment. The method includes contacting the equipment with a cleaning concentrate dissolved in water. The cleaning concentrate contains (i) a biofilm permeation agent, (ii) a nonionic alkoxylated alcohol surfactant having an HLB ranging from about 5 to less than 8, wherein a weight ratio of (i) to (ii) in the cleaning concentrate based on 100 wt. % active ingredients ranges from about 0.5:1 to about 1.5:1, and (iii) and an inert diluents. After contacting the equipment with the cleaning concentrate dissolved in water, the contacted surfaces are rinsed to substantially remove detectible traces of the ingredients of the cleaning concentrate from the surfaces.
    Type: Grant
    Filed: August 16, 2013
    Date of Patent: November 18, 2014
    Assignee: Innovation Services, Inc.
    Inventors: Joseph B. Dooley, Jeffrey G. Hubrig
  • Publication number: 20140311529
    Abstract: The present invention relates to [1] a detergent composition for endoscope washers, including a nonionic surfactant (A) represented by the following formula (1), a branched-chain fatty acid having not less than 6 and not more than 10 carbon atoms or a salt thereof (B), a defoaming agent (C) and water, R—O—[(EO)m/(PO)n]—H??(1) wherein R represents a branched-chain alkyl group having not less than 7 and not more than 9 carbon atoms; EO represents an ethanediyloxy group; PO represents a propanediyloxy group; m and n each represent an average molar number of addition of the ethanediyloxy or propanediyloxy group in which m is a number of not less than 1 and not more than 30, and n is a number of not less than 2 and not more than 50; and the mark “/” represents that EO and PO may be added either in a random form or in a block form, and an order of addition of EO and PO is optional; and [2] a method of washing an endoscope using an endoscope washer, including the step of washing the endoscope with a mixture inclu
    Type: Application
    Filed: May 28, 2013
    Publication date: October 23, 2014
    Inventors: Masaya Nishio, Tatsuya Sakai
  • Publication number: 20140314733
    Abstract: Composition for the removal of biofilms present on a substrate, comprising at least one detergent component comprising at least one sequestering agent and at least one agent that is simultaneously a wetting and a dispersing agent, and at least one enzymatic component containing at least one protease, at least one laccase and at least one polysaccharidase
    Type: Application
    Filed: April 19, 2013
    Publication date: October 23, 2014
    Applicant: S.A. Realco
    Inventors: Gauthier Boels, Gordon Blackman, Sébastien Fastrez
  • Publication number: 20140308366
    Abstract: The present invention relates to novel sulfoperoxycarboxylic acid compounds, and methods for making and using them. The sulfoperoxycarboxylic compounds of the invention are storage stable, water soluble and have low to no odor. Further, the compounds of the present invention can be formed from non-petroleum based renewable materials. The compounds of the present invention can be used as antimicrobials, and bleaching agents. The compounds of the present invention are also suitable for use as coupling agents.
    Type: Application
    Filed: June 27, 2014
    Publication date: October 16, 2014
    Inventors: Junzhong Li, Richard Staub, David D. McSherry, Keith G. Lascotte, Steven J. Lange, Frank Everts
  • Patent number: 8853278
    Abstract: Compounds, compositions, and methods comprising a polyamine compound are described, which may be used to kill, disperse, treat, reduce biofilms, and/or inhibit or substantially prevent biofilm formation. In certain aspects, the present invention relates to compounds, compositions, and methods comprising polyamine compounds that have antimicrobial or dispersing activity against a variety of bacterial strains capable of forming biofilms.
    Type: Grant
    Filed: November 8, 2013
    Date of Patent: October 7, 2014
    Assignees: Curza Global, LLC, University of Utah Research Foundation
    Inventors: Ryan Looper, Dustin Williams, Sujeevini Jeyapalina, Travis Haussener, Paul R. Sebahar, Hari Kanna Reddy
  • Publication number: 20140256025
    Abstract: A composition for cleaning a medical instrument having a surface at least partially covered by a biofilm. The composition may include a first enzyme having a weight of less than about 10% of the total weight of the composition, a second enzyme having a weight of less than about 10% of the total weight of the composition, and a surfactant having a weight less than about 10% of the total weight of the composition. The second enzyme may be different from the first enzyme. Additionally, the composition may have a pH ranging from about 4 to about 12, and the composition may be configured to remove greater than about 90% of the biofilm from the medical instrument in less than about 10 minutes.
    Type: Application
    Filed: March 4, 2014
    Publication date: September 11, 2014
    Applicant: RUHOF CORPORATION
    Inventors: Marc B. Esquenet, Bernard E. Esquenet, Lee A. Ruvinsky, Alcides Martinez
  • Publication number: 20140235521
    Abstract: Methods employing detergent compositions effective for reducing hard water scale and accumulation on hard surfaces, namely within food, beverage and pharmaceutical applications are disclosed. The detergent compositions employ phosphinosuccinic acid adducts in combination with an alkalinity source and optionally polymers, surfactants and/or oxidizers, providing alkaline compositions having a pH between about 10 and 13.5.
    Type: Application
    Filed: April 24, 2014
    Publication date: August 21, 2014
    Applicant: Ecolab USA Inc.
    Inventors: Carter M. Silvernail, Erik C. Olson, Michel M. Lawrence, Richard D. Johnson, Steven J. Lange
  • Publication number: 20140212459
    Abstract: The invention relates to 10H-benzo[g]pteridine-2,4-dione derivatives, to the production thereof, and to the use thereof.
    Type: Application
    Filed: June 22, 2012
    Publication date: July 31, 2014
    Inventors: Tim Maisch, Andreas Späth
  • Patent number: 8765652
    Abstract: The present invention relates to reagents for use in deactivating nucleic acids and methods of making and using the same.
    Type: Grant
    Filed: June 25, 2012
    Date of Patent: July 1, 2014
    Assignee: Gen-Probe Incorporated
    Inventors: Norman C. Nelson, Kenneth A. Browne, Lizhong Dai, James Russell, Mark E. Filipowsky, Margarita B. Kaminsky, Daniel L. Kacian
  • Patent number: 8685904
    Abstract: An aqueous lubricant emulsion for medical or food apparatus, comprising: (a) 5 wt % to 30 wt % of a mineral oil; (b) 5 wt % to 30 wt % of an emulsifier system consisting of two emulsifiers selected from the group consisting of sorbitan fatty acid ester, polyoxyethylene sorbitan fatty acid ester, oleyl alcohol ether, triethanolamine oleate, wherein the mass ratio of the two emulsifiers is in a range of 2:8 to 8:2; (c) 0.5 wt % to 5 wt % of one or more coemulsifiers selected from the group consisting of fatty alcohols, long-chain fatty acids, and diisooctyl succinate sulfonates; and (d) the balance of water. A method for washing medical or food apparatus including the step of subjecting the medical or food apparatus to a treatment using the lubricant emulsion according to the invention after a washing step for the medical or food apparatus is also described.
    Type: Grant
    Filed: June 19, 2009
    Date of Patent: April 1, 2014
    Assignee: 3M Innovative Properties Company
    Inventors: Ying Wei Xie, Xiaolei Jia
  • Patent number: 8658190
    Abstract: The addition of alcohol plus acetate salts unexpectedly enhanced the tuberculocidal activity of glutaraldehyde, and decreased the fumes of glutaraldehyde from the formula of a high-level disinfectant.
    Type: Grant
    Filed: July 11, 2005
    Date of Patent: February 25, 2014
    Assignee: DFB Technology, Ltd.
    Inventor: Norman A. Miner
  • Patent number: 8647443
    Abstract: A method of cleaning an automatic biochemical analyzer, wherein the cleaning solution includes: at least one anionic surfactant, at least one nonionic surfactant, an alkali metal hydroxide, an alkali metal citrate, and a buffering agent stabilizing the pH value above 13.0. In some embodiments, the cleaning solution provides low residual rate of proteins, low residual rate of lipids, desirable within-batch repeatability in clinical testing, low level of cross-contamination, and low level of reactant deposit after cleaning, without affecting test results of the biochemical analyzer. In some embodiments, the cleaning solution has no corrosive effects on the liquid path and reaction cup of the analyzer. The ingredients of the cleaning solution may also be biodegradable.
    Type: Grant
    Filed: May 20, 2011
    Date of Patent: February 11, 2014
    Assignee: Shenzhen Mindray Bio-Medical Electronics Co., Ltd.
    Inventors: Yuping Zhang, Mulong Liu, Wenjuan Xu, Jun Cheng
  • Publication number: 20140039051
    Abstract: The invention relates to a cleaner and/or disinfectant for medical and/or surgical elements and apparatuses which is formulated as a powder. It comprises at least one peroxide, at least one acylating agent for releasing peracetic acid from the peroxide in aqueous solution, and also at least one nonionic surfactant. According to the invention, it is provided that it comprises agents for adjusting a pH of a 2% strength aqueous solution to pH 7.5 to 9 and is formulated as granules, where peroxide and/or acylating agent are coated with nonionic surfactant.
    Type: Application
    Filed: August 1, 2013
    Publication date: February 6, 2014
    Applicant: Chemische Fabrik Dr. Weigert GmbH & Co. KG
    Inventors: Iris Strodtholz, Verona Schmidt, Markus Kamer
  • Publication number: 20140034089
    Abstract: A medical surface cleaning composition and a method for cleaning waste treatment system components, medical instruments surfaces, and enzyme residue-containing surfaces. The composition includes a residue cleaning agent and a substantially non-water soluble nonionic surfactant having an initial Ross-Miles foam height in an aqueous solution at 25° C. of less than 10 millimeters. A weight ratio of residue cleaning agent to surfactant on 100 wt. % active ingredient basis ranges from about 0.05:1 to about 0.5:1, and wherein the residue cleaning agent and surfactant are biodegradable.
    Type: Application
    Filed: October 10, 2013
    Publication date: February 6, 2014
    Applicant: INNOVATION SERVICES, INC.
    Inventor: Jeffrey G. Hubrig
  • Publication number: 20140007900
    Abstract: The present invention provides a liquid composition for removing dental cement from the surface of non-living objects, comprising i) an inorganic base; ii) a complexing agent; iii) optionally a surfactant; and iv) an aqueous solvent. In a preferred embodiment, the composition comprises a surfactant, and an aqueous solvent comprising water mixed with a polar solvent miscible with water, preferably alcohol. Said objects to be cleaned comprise workpieces and instruments used in restoration work. Said workpieces may comprise crowns, bridges, inlays, and other prostheses. Said instruments may, comprise, for example, tools used during the dental operation which contacted the cement.
    Type: Application
    Filed: February 20, 2012
    Publication date: January 9, 2014
    Inventor: Joseph Fish
  • Publication number: 20130333730
    Abstract: A medical instrument cleaning concentrate and method for cleaning medical equipment. The method includes contacting the equipment with a cleaning concentrate dissolved in water. The cleaning concentrate contains (i) a biofilm permeation agent, (ii) a nonionic alkoxylated alcohol surfactant having an HLB ranging from about 5 to less than 8, wherein a weight ratio of (i) to (ii) in the cleaning concentrate based on 100 wt. % active ingredients ranges from about 0.5:1 to about 1.5:1, and (iii) and an inert diluents. After contacting the equipment with the cleaning concentrate dissolved in water, the contacted surfaces are rinsed to substantially remove detectible traces of the ingredients of the cleaning concentrate from the surfaces.
    Type: Application
    Filed: August 16, 2013
    Publication date: December 19, 2013
    Applicant: Innovation Services, Inc.
    Inventors: Joseph B. Dooley, Jeffrey G. Hubrig
  • Publication number: 20130298946
    Abstract: A medical waste pretreatment and/or conditioner composition comprising a lipid agglomeration inhibitor and a surfactant having an HLB value ranging from about 1 to less than about 5, wherein a weight ratio of agglomeration inhibitor to surfactant on 100 wt. % active ingredient basis ranges from about 0.015:1 to about 3:1.
    Type: Application
    Filed: July 19, 2013
    Publication date: November 14, 2013
    Inventor: Jeffrey G. Hubrig
  • Publication number: 20130296213
    Abstract: The present invention discloses the method for cleaning a medical instrument using a treatment liquid, wherein the treatment liquid contains: (A) an alkanolamine in an amount of 0.004 to 1% by mass, (B) a nonionic surfactant in an amount of 0.002 to 1% by mass, (C) a polyhydric alcohol in an amount of 0.004 to 10% by mass, (D) an alkaline protease in an effective amount, and (E) water, and has a pH of not lower than 9.
    Type: Application
    Filed: December 28, 2010
    Publication date: November 7, 2013
    Applicant: KAO CORPORATION
    Inventors: Kazuo Isobe, Masaya Nishio, Tatsuya Sakai
  • Publication number: 20130289114
    Abstract: Acetyl xylan esterases and variants thereof having perhydrolytic activity are provided for producing peroxycarboxylic acids from carboxylic acid esters and a source of peroxygen. Multi-component peracid generation systems comprising an enzyme catalyst having perhydrolytic activity are also provided, as are methods of using the present enzyme catalyst to produce peroxycarboxylic acids. The polypeptide having perhydrolytic activity may be used to produce peroxycarboxylic acids suitable for use in a variety of applications such as cleaning, disinfecting, sanitizing, bleaching, wood pulp processing, paper pulp processing, and personal care applications.
    Type: Application
    Filed: March 13, 2013
    Publication date: October 31, 2013
    Inventors: Mark Scott PAYNE, Robert DiCosimo
  • Publication number: 20130261182
    Abstract: Acetyl xylan esterases and variants thereof having perhydrolytic activity are provided for producing peroxycarboxylic acids from carboxylic acid esters and a source of peroxygen. Multi-component peracid generation systems comprising an enzyme catalyst having perhydrolytic activity are also provided, as are methods of using the present enzyme catalyst to produce peroxycarboxylic acids. The polypeptide having perhydrolytic activity may be used to produce peroxycarboxylic acids suitable for use in a variety of applications such as cleaning, disinfecting, sanitizing, bleaching, wood pulp processing, paper pulp processing, and personal care applications.
    Type: Application
    Filed: March 13, 2013
    Publication date: October 3, 2013
    Applicant: E. I. DU PONT DE NEMOURS AND COMPANY
    Inventors: Mark Scott PAYNE, Robert DiCosimo
  • Patent number: 8536105
    Abstract: A medical instrument cleaning concentrate and method for cleaning medical equipment. The concentrate contains an active ingredient consisting essentially of (i) a biofilm permeation agent and (ii) a nonionic alkoxylated alcohol surfactant having an HLB ranging from about 5 to about 8, wherein a ratio of (i) to (ii) in the concentrate ranges from about 2:1 to about 4:1.
    Type: Grant
    Filed: June 8, 2010
    Date of Patent: September 17, 2013
    Assignee: Innovation Services, Inc.
    Inventors: Joseph B. Dooley, Jeffrey G. Hubrig
  • Patent number: 8486896
    Abstract: There is provided a hydrogelator that is capable of forming a hydrogel with an extremely small amount thereof over a liquid property range from acidic to alkaline, and a hydrogel having high environmental suitability, biocompatibility and biodegradability. A hydrogelator comprising a lipid peptide represented by Formula (1): (where R1 represents an aliphatic group having 9 to 21 carbon atoms; R2, R3 and R4 independently represent a hydrogen atom, an alkyl group having 1 to 4 carbon atom(s) which may have a branched chain having 1 or 2 carbon atom(s), a phenylmethyl group or a —(CH2)n—X group, and at least one of R2, R3 and R4 represents a —(CH2)n—X group; n represents the number of 1 to 4; X represents an amino group, a guanidino group, a —CONH2 group or a 5-membered ring, a 6-membered ring or a fused heterocyclic ring composed of a 5-membered ring and a 6-membered ring which may have 1 to 3 nitrogen atom(s)) or a salt thereof, and a hydrogel comprising the hydrogelator.
    Type: Grant
    Filed: July 4, 2008
    Date of Patent: July 16, 2013
    Assignees: Nissan Chemical Industries, Ltd., Kyushu University
    Inventors: Nobuhide Miyachi, Takehisa Iwama, Masahiro Gotoh, Tatsuo Maruyama, Daisuke Koda
  • Patent number: 8435933
    Abstract: A method for monitoring cleaning of a surface includes applying an amount of transparent indicator material to an area of a surface and measuring the amount of transparent indicator material remaining on the surface. The transparent indicator material may be fixed on the surface by drying and, when a fluorescent material, may be measured through exposure to ultraviolet radiation.
    Type: Grant
    Filed: November 28, 2011
    Date of Patent: May 7, 2013
    Assignee: Kleancheck Systems, LLC
    Inventor: Philip C. Carling
  • Publication number: 20130102672
    Abstract: An acetyl xylan esterase variant having perhydrolytic activity is provided for producing peroxycarboxylic acids from carboxylic acid esters and a source of peroxygen. More specifically, a Thermotoga maritima acetyl xylan esterase gene was modified using error-prone PCR and site-directed mutagenesis to create an enzyme catalyst characterized by an increase in specific activity. The variant acetyl xylan esterase may be used to produce peroxycarboxylic acids suitable for use in a variety of applications such as cleaning, disinfecting, sanitizing, bleaching, wood pulp processing, and paper pulp processing applications.
    Type: Application
    Filed: October 22, 2012
    Publication date: April 25, 2013
    Applicant: E. I. DU PONT DE NEMOURS AND COMPANY
    Inventor: E.I. Du Pont De Nemours And Company
  • Patent number: 8420584
    Abstract: A non-toxic enzymatic detergent for use in cleaning surgical instruments and the like which have a large build-up of bio-residue thereon and which need specialty cleaning in order to avoid both hardened bio-residue and certain fluid traces from the instruments for both operating accuracy as well as sterilization requirements.
    Type: Grant
    Filed: June 4, 2010
    Date of Patent: April 16, 2013
    Inventors: Melton Sherwood Thoele, Alex Ladato
  • Patent number: 8382912
    Abstract: A biofilm-removing agent which effectively removes biofilms is provided. A biofilm-removing agent containing a basic amino acid derivative represented by the following formula (1) or a salt thereof: (wherein R1 represents a linear- or branched-alkyl group having 4 to 18 carbon atoms or a linear- or branched-alkenyl group having 4 to 18 carbon atoms; X and Y each represent a group selected from the groups represented by the following formulas: and m represents an integer from 1 to 5).
    Type: Grant
    Filed: November 27, 2008
    Date of Patent: February 26, 2013
    Assignee: KAO Corporation
    Inventors: Kazuo Isobe, Yuji Okauchi
  • Patent number: 8343903
    Abstract: There is disclosed a cleaning composition comprising (i) 0.1 to 10 percent by weight of the cleaning composition of a biofilm removing detergent solution comprising a combination of an alkyl (C8-18) polysaccharide, a non-ionic surfactant and a nitrogen containing surfactant-biocide (ii) 2 to 80 percent by weight of the cleaning composition of one or more polar solvent (iii) 0.5 to 15 percent by weight of the cleaning composition of one or more primary amine (iv) two or more chelating agents (v) 0.1 to 5.0 percent by weight of the cleaning composition of an alkaline buffer system providing a pH of about 11.5 to 13.3 in aqueous solution (vi) 0.005 to 5.0 percent by weight of the cleaning composition of an alkoxyaminosilane. Also disclosed is a process of cleaning, decontaminating and/or passivating metallic surgical instruments and/or equipment using the composition of the invention.
    Type: Grant
    Filed: July 16, 2009
    Date of Patent: January 1, 2013
    Assignee: Whiteley Holdings Pty Ltd
    Inventor: Reginald Keith Whiteley
  • Patent number: 8227397
    Abstract: The disclosure relates to an enzyme stabilization system, compositions with the enzyme stabilization system, and methods of using the enzyme composition. Preferred ratios of acid to amine are effective at stabilizing enzyme. Optional nonionic surfactants and solvents also positively contribute to enzyme stability. The compositions are useful in cleaning applications.
    Type: Grant
    Filed: May 11, 2011
    Date of Patent: July 24, 2012
    Assignee: Ecolab USA Inc.
    Inventors: Brandon L. Herdt, Werner Strothoff, Alice Siegmann
  • Publication number: 20120172271
    Abstract: An alkaline composition having a pH ranging from about 8.5 to about 10 comprising a first substantially hydrophilic nonionic alkoxylated alcohol surfactant having an HLB value ranging from about 12 to about 15; a second substantially hydrophilic nonionic alkoxylated alcohol surfactant having an HLB value ranging from about 16 to 20; a bio-film permeation agent; and an aqueous solvent, wherein a total amount of the first substantially hydrophilic nonionic alkoxylated alcohol surfactant and the second substantially hydrophilic nonionic alkoxylated alcohol surfactant in the alkaline composition ranges from about 2 to about 20 percent by weight of a total weight of the alkaline composition.
    Type: Application
    Filed: March 7, 2012
    Publication date: July 5, 2012
    Applicant: STRYKER CORPORATION
    Inventors: Jeffrey G. Hubrig, Joseph B. Dooley
  • Publication number: 20120108484
    Abstract: The invention relates to the use of an agent that contains 5 to 99.9% by weight of carbamide and/or at least a derivative thereof, as a cleaning agent e.g. for closed systems, in particular as a dishwasher detergent, as a laundry detergent for washing machines, as an agent for cleaning, sanitizing and/or disinfecting for equipment in the food processing industry and for medical equipment, the use as a hand dishwashing detergent or sanitary cleaner or as a hand cleaner.
    Type: Application
    Filed: March 17, 2010
    Publication date: May 3, 2012
    Applicant: BBT Bergedorfer Biotechnik GmbH
    Inventors: Klaus Becker, Manfred Haake
  • Patent number: 8163101
    Abstract: A method for cleaning contaminated surfaces of surgical waste management equipment. The method includes rinsing surfaces of the equipment with water to remove water soluble contaminants and waste material. A rinse solution is applied to the surfaces of the equipment to provide a residual film thereon. The rinse solution includes a first nonionic alkoxylated alcohol surfactant having an HLB value ranging from about 12 to about 15, a second nonionic alkoxylated alcohol surfactant having an HLB value ranging from about 16 to 20, an aqueous solvent, and a bio-film permeation agent. A total of the first surfactant and the second surfactant in the composition ranges from about 2 to about 20 percent by weight of a total weight of the composition.
    Type: Grant
    Filed: January 13, 2011
    Date of Patent: April 24, 2012
    Assignee: Stryker Corporation
    Inventors: Joseph B. Dooley, Jeffrey G. Hubrig, Richard H. Devault, Rodney D. Parker, John M. Izenbaard
  • Patent number: 8119584
    Abstract: The present disclosure generally relates to a method for cleaning a shaving device using a cleaning solution and preparation of the cleaning solution. More particularly, the present disclosure relates to a method of cleaning a shaving device using an environmentally friendly cleaning solution.
    Type: Grant
    Filed: July 19, 2010
    Date of Patent: February 21, 2012
    Assignee: Rovcal, Inc.
    Inventors: Richard A. Harthun, David W. Everett, Giovanni Gonzalez
  • Publication number: 20120035089
    Abstract: Methods of cleaning a medical device are provided via exposing the medical device to a compressed CO2-based mixture. The compressed CO2-based mixture includes carbon dioxide, a surfactant, and water in the form of water-in-CO2 microemulsions. In one particular embodiment, the ratio of water-to-surfactant mixed together in the CO2 has a range of about 5-100 molecules of water per molecule of surfactant (e.g., about 5-30 molecules of water per molecule of surfactant).
    Type: Application
    Filed: August 3, 2011
    Publication date: February 9, 2012
    Applicant: UNIVERSITY OF SOUTH CAROLINA
    Inventors: Michael A. Matthews, Pedro J. Tarafa
  • Patent number: 8110538
    Abstract: A microbicidal and decontaminant composition comprising an aqueous solution of peroxides and peracids having equilibrium reaction products, a photoreactive surfactant, and a polymer, wherein said polymer interacts with said peroxides and said peracids.
    Type: Grant
    Filed: January 11, 2006
    Date of Patent: February 7, 2012
    Assignee: BioMed Protect, LLC
    Inventors: Charles W. Martin, Joan A. Stader, Jeffry Golden
  • Patent number: 8084410
    Abstract: A method for monitoring cleaning of a surface includes applying an amount of transparent indicator material to an area of a surface and measuring the amount of transparent indicator material remaining on the surface. The transparent indicator material may be fixed on the surface by drying and, when a fluorescent material, may be measured through exposure to ultraviolet radiation.
    Type: Grant
    Filed: October 21, 2008
    Date of Patent: December 27, 2011
    Assignee: Kleancheck Systems, LLC
    Inventor: Philip C. Carling
  • Patent number: 8084411
    Abstract: The present invention is drawn to disinfectant systems and methods which can be used to produce a disinfectant solution. The system can include a first liquid composition and a second liquid composition. The first liquid composition comprises from 0.0005 ppm to 100,000 ppm by weight of a transition metal or alloy and an alcohol, and the second liquid composition comprises water and a peroxygen compound. The first and second liquid compositions are formulated to be combined so as to yield a resultant disinfectant solution. The disinfectant solution can be used to disinfect a variety of surfaces and even liquid compositions.
    Type: Grant
    Filed: June 30, 2008
    Date of Patent: December 27, 2011
    Assignee: Solutions BioMed, LLC
    Inventors: Daryl J. Tichy, Brian G. Larson
  • Publication number: 20110311644
    Abstract: The present invention describes a balanced aqueous electrolyte solution. In particular, a balanced aqueous electrolyte solution that is particularly suitable as a solution for intravenous and subcutaneous infusion because of its being plasma-adapted is described. In addition to the balanced electrolyte solution itself, an electrolyte mixture as well as a process for preparing the balanced electrolyte solution from this mixture, and a medicament comprising the solution and optionally an active ingredient are provided.
    Type: Application
    Filed: March 8, 2010
    Publication date: December 22, 2011
    Applicant: B. BRAUN MELSUNGEN AG
    Inventor: Michael Boll