Ortho-hydroxybenzoic Acid (i.e., Salicyclic Acid) Or Derivative Doai Patents (Class 514/159)
  • Patent number: 10231943
    Abstract: The present specification discloses pharmaceutical compositions, methods of preparing such pharmaceutical compositions, and methods and uses of treating a cardiovascular disease in an individual using such pharmaceutical compositions.
    Type: Grant
    Filed: September 12, 2017
    Date of Patent: March 19, 2019
    Assignee: Infirst Healthcare Limited
    Inventors: Robin Mark Bannister, John Brew, Suzanne Jane Dilly, Gregory Alan Stoloff, Wilson Caparros Wanderley
  • Patent number: 10231995
    Abstract: The use of selenite- or selenate-containing preparations supplemented with pharmaceutically acceptable or food-compatible acids for the preparation of an agent intended for topical or buccal application or mucosal administration is described.
    Type: Grant
    Filed: October 5, 2017
    Date of Patent: March 19, 2019
    Assignee: SELO MEDICAL GMBH
    Inventors: Bodo Kuklinski, Peter Kössler, Norbert Fuchs
  • Patent number: 10213381
    Abstract: The present specification discloses pharmaceutical compositions, methods of preparing such pharmaceutical compositions, and methods and uses of treating a chronic inflammation and/or an inflammatory disease in an individual using such pharmaceutical compositions.
    Type: Grant
    Filed: August 23, 2017
    Date of Patent: February 26, 2019
    Assignee: infirst Healthcare Limited
    Inventors: Robin M. Bannister, John Brew, Richard R. Reiley, III, Wilson Caparros Wanderley
  • Patent number: 10172847
    Abstract: A method for reducing, inhibiting, and eliminating inflammation and pain by using an effective amount of iron chelator composition to balance oxidative activity at a cutaneous site of inflammation and pain. The composition contained in transdermal formulations and administered topically in accordance with the invention can be combined with one or more suitable carriers and can be administered in conjunction with one or more additional therapeutic agents.
    Type: Grant
    Filed: May 13, 2016
    Date of Patent: January 8, 2019
    Inventor: Kenneth Russell
  • Patent number: 10155042
    Abstract: The present specification discloses pharmaceutical compositions, methods of preparing such pharmaceutical compositions, and methods and uses of treating a chronic inflammation and/or an inflammatory disease in an individual using such pharmaceutical compositions.
    Type: Grant
    Filed: June 5, 2017
    Date of Patent: December 18, 2018
    Assignee: Infirst Healthcare Limited
    Inventors: Robin M. Bannister, John Brew, Wilson Caparros-Wanderely, Suzanne J. Dilly, Olga Pleguezeulos Mateo, Gregory A. Stoloff
  • Patent number: 10004704
    Abstract: The present specification discloses pharmaceutical compositions, methods of preparing such pharmaceutical compositions, and methods and uses of treating a chronic inflammation and/or an inflammatory disease in an individual using such pharmaceutical compositions.
    Type: Grant
    Filed: May 31, 2016
    Date of Patent: June 26, 2018
    Assignee: Infirst Healthcare Limited
    Inventors: Robin Mark Bannister, John Brew, Wilson Caparros-Wanderley, Gregory Alan Stoloff, Suzanne Jane Dilly, Gemma Szucs, Olga Pleguezuelos Mateo
  • Patent number: 9987215
    Abstract: The present invention relates to process for preparing cosmetic compositions at two stages. The first relates to the preparation of organogels in which liquid oils are structured by a mixture of structuring agents such as monoglycerides and waxes, which also have the addition of other components such as polymers and polyol esters. The second step is the formation of the cold or hot process cosmetic compositions where emulsions are prepared by the addition of water, aqueous solutions and other components, to the organogel. The emulsions prepared have superior sensory, chemical-physical and stability characteristics, to those currently produced by the classic technology of preparation with emulsifiers.
    Type: Grant
    Filed: March 22, 2013
    Date of Patent: June 5, 2018
    Assignee: CHEMYUNION QUIMICA LTDA.
    Inventors: Cecilia Nogueira, Cristiane Rodrigues da Silva Pacheco, Daniel Barrera Arellano, Daniele Cristina Zulim Botega, Mario Luiz Mathias Netto
  • Patent number: 9901638
    Abstract: A combination of antibiotics including rifabutin, clarithromycin and clofazimine for the treatment of an autoimmune disease such as multiple sclerosis and related diseases. In a further aspect, there is provided a composition comprising a combination of two or more antibiotic agents for the treatment of an autoimmune disease, said two or more antibiotic agents selected from rifabutin, clofazimine, and at least one macrolide.
    Type: Grant
    Filed: September 19, 2012
    Date of Patent: February 27, 2018
    Assignee: RedHill Biopharma Ltd.
    Inventors: Reza Fathi, Patrick Laughlin McLean, Harry Jefferson Leighton
  • Patent number: 9827215
    Abstract: The present specification discloses pharmaceutical compositions, methods of preparing such pharmaceutical compositions, and methods and uses of treating a chronic inflammation and/or an inflammatory disease in an individual using such pharmaceutical compositions.
    Type: Grant
    Filed: June 28, 2016
    Date of Patent: November 28, 2017
    Assignee: Infirst Healthcare Limited
    Inventors: Robin M. Bannister, John Brew, Richard R. Reiley, III, Wilson Caparros Wanderley
  • Patent number: 9820952
    Abstract: The present specification discloses pharmaceutical compositions, methods of preparing such pharmaceutical compositions, and methods and uses of treating a chronic inflammation and/or an inflammatory disease in an individual using such pharmaceutical compositions.
    Type: Grant
    Filed: June 28, 2016
    Date of Patent: November 21, 2017
    Assignee: Infirst Healthcare Limited
    Inventors: Robin M. Bannister, John Brew, Richard R. Reiley, III, Wilson Caparros Wanderley
  • Patent number: 9789075
    Abstract: The present specification discloses pharmaceutical compositions, methods of preparing such pharmaceutical compositions, and methods and uses of treating a cardiovascular disease in an individual using such pharmaceutical compositions.
    Type: Grant
    Filed: July 25, 2016
    Date of Patent: October 17, 2017
    Assignee: Infirst Helathcare Limited
    Inventors: Robin Mark Bannister, John Brew, Suzanne Jane Dilly, Gregory Alan Stoloff, Wilson Caparros-Wanderley
  • Patent number: 9750810
    Abstract: The present specification discloses pharmaceutical compositions, methods of preparing such pharmaceutical compositions, and methods and uses of treating a chronic inflammation and/or an inflammatory disease in an individual using such pharmaceutical compositions.
    Type: Grant
    Filed: February 12, 2016
    Date of Patent: September 5, 2017
    Assignee: Infirst Healthcare Limited
    Inventors: Robin M. Bannister, John Brew, Wilson Caparros-Wanderely, Suzanne J. Dilly, Olga Pleguezeulos Mateo, Gregory A. Stoloff
  • Patent number: 9744132
    Abstract: The present specification discloses pharmaceutical compositions, methods of preparing such pharmaceutical compositions, and methods and uses of treating a chronic inflammation and/or an inflammatory disease in an individual using such pharmaceutical compositions.
    Type: Grant
    Filed: August 7, 2015
    Date of Patent: August 29, 2017
    Assignee: Infirst Healthcare Limited
    Inventors: Robin M. Bannister, John Brew, Richard R. Reiley, III, Wilson Caparros Wanderley
  • Patent number: 9737698
    Abstract: A method and system for treating patients with Alzheimer disease includes steps and equipment operative for subjecting a patient suffering from Alzheimer disease to a non-invasive action directed toward a patient's brain and causing a cavitation process in the patient's brain liquid in the vicinity of lesions and thereby destroying the latter.
    Type: Grant
    Filed: January 4, 2016
    Date of Patent: August 22, 2017
    Inventors: Mikhail Topchiashvili, Luba Chigirinskay, Marika Cherfas
  • Patent number: 9717667
    Abstract: An oral care composition is provided wherein the composition comprises an ionic liquid, wherein the ionic liquid comprises: a) a quaternary ammonium cation of the formula wherein R1, R2, R3 and R4 are each an organic moiety and may be the same or different, and at least one of R1, R2, R3 and R4 includes a hydroxyl; and b) an anion selected from the group consisting of salicylate, alkylsulfate, sulfate, acetate, halide, phosphate, alkyl phosphate and tosylate; wherein the oral care composition is a mouth rinse, toothpaste, toothpowder, oral bead or strip, fluid-encased dental strip, irrigation fluid, plaque removal liquid, dental floss, hard candy, soft candy, lozenge, chewing gum, or lollipop.
    Type: Grant
    Filed: December 20, 2012
    Date of Patent: August 1, 2017
    Assignee: Colgate-Palmolive Company
    Inventors: Madhusudan Patel, Guillaume Picquet, Mark Vandeven, Mahmoud Hassan, Rosa Paredes
  • Patent number: 9693980
    Abstract: The present specification discloses pharmaceutical compositions, methods of preparing such pharmaceutical compositions, and methods and uses of treating a chronic inflammation and/or an inflammatory disease in an individual using such pharmaceutical compositions.
    Type: Grant
    Filed: May 31, 2016
    Date of Patent: July 4, 2017
    Assignee: Infirst Healthcare Limited
    Inventors: Robin Mark Bannister, John Brew, Wilson Caparros-Wanderley, Gregory Alan Stoloff, Suzanne Jane Dilly, Gemma Szucs, Olga Pleguezuelos Mateo
  • Patent number: 9670121
    Abstract: The present invention aims to provide a compound superior in broad utility and stability, which is useful as a protecting reagent (anchor) of amino acid and/or peptide in liquid phase synthesis and the like of a peptide having a C-terminal etc., which are of a carboxamide (—CONHR)-type, an organic synthesis reaction method (particularly peptide liquid phase synthesis method) using the compound, and a kit for peptide liquid phase synthesis containing the compound, and has found that the object can be achieved by a particular compound having a diphenylmethane skeleton.
    Type: Grant
    Filed: August 28, 2015
    Date of Patent: June 6, 2017
    Assignee: AJINOMOTO CO., INC.
    Inventor: Daisuke Takahashi
  • Patent number: 9649502
    Abstract: Described herein, in certain embodiments, are devices and methods for modulating the electrical activity of a brain in a targeted manner using a weak magnetic field, generally field with a strength of less than about 100 Gauss. The magnetic field is varied over time in a periodic manner, generally with a frequency tuned to specifically affect one of the intrinsic frequencies of the brain, optionally the alpha frequency. The “Low Field Magnetic Stimulation” devices and methods described herein modulate the electrical activity of a brain without requiring medication. Methods and devices described herein gently “tune” the brain and affect mood, focus, and cognition of human subjects.
    Type: Grant
    Filed: November 13, 2012
    Date of Patent: May 16, 2017
    Assignee: NEOSYNC, INC.
    Inventors: James William Phillips, Yi Jin
  • Patent number: 9604925
    Abstract: Disclosed are compositions and methods for treating bacterial infections.
    Type: Grant
    Filed: May 8, 2015
    Date of Patent: March 28, 2017
    Assignee: Purdue Research Foundation
    Inventors: Cynthia Stauffacher, Mark Alfred Lipton, Mohamed Naguieb Seleem, Tim Jonathan Schmidt, Calvin Nicklaus Steussy, Jr., Victor W Rodwell
  • Patent number: 9596379
    Abstract: Provided is an image reading apparatus capable of reading an image of an original at a high resolution by an image pickup unit by reducing an influence of a dark line included in a projection image on an original placing stand, which is ascribable to a displaying element included in a projecting unit and is to be exerted on an original placed on original placing stand. The image reading apparatus includes: an image pickup unit conducting image pickup for a placing surface; a projecting unit projecting an image on placing surface; and a switching unit switching a blur amount of image on placing surface, in which the switching unit sets a blur amount of image in a first mode, in which the image pickup is not conducted by image pickup unit, smaller than that in a second mode, in which the image pickup is conducted by image pickup unit.
    Type: Grant
    Filed: March 1, 2016
    Date of Patent: March 14, 2017
    Assignee: CANON KABUSHIKI KAISHA
    Inventor: Ikutaro Mitsutake
  • Patent number: 9381180
    Abstract: The present specification discloses pharmaceutical compositions, methods of preparing such pharmaceutical compositions, and methods and uses of treating a chronic inflammation and/or an inflammatory disease in an individual using such pharmaceutical compositions.
    Type: Grant
    Filed: October 21, 2014
    Date of Patent: July 5, 2016
    Assignee: Infirst Healthcare Limited
    Inventors: Robin Mark Bannister, John Brew, Wilson Caparros-Wanderley, Gregory Alan Stoloff, Suzanne Jane Dilly, Gemma Szucs, Olga Pleguezuelos Mateo
  • Patent number: 9358242
    Abstract: Calcium glycerophosphate is found to be effective in treating and preventing a disease, disorder and/or condition of the respiratory system. The disease, disorder and/or condition is related to an obstructive or a restrictive condition of the respiratory airway.
    Type: Grant
    Filed: March 1, 2010
    Date of Patent: June 7, 2016
    Assignee: Prelief Inc.
    Inventors: Alan E. Kligerman, Margaret T. Weis
  • Patent number: 9326958
    Abstract: The present specification discloses pharmaceutical compositions, methods of preparing such pharmaceutical compositions, and methods and uses of treating a chronic inflammation and/or an inflammatory disease in an individual using such pharmaceutical compositions.
    Type: Grant
    Filed: October 21, 2014
    Date of Patent: May 3, 2016
    Assignee: INFIRST HEALTHCARE LIMITED
    Inventors: Robin Mark Bannister, John Brew, Wilson Caparros-Wanderley, Gregory Alan Stoloff, Suzanne Jane Dilly, Gemma Szucs, Olga Pleguezuelos Mateo
  • Patent number: 9308213
    Abstract: The present specification discloses pharmaceutical compositions, methods of preparing such pharmaceutical compositions, and methods and uses of treating a chronic inflammation and/or an inflammatory disease in an individual using such pharmaceutical compositions.
    Type: Grant
    Filed: January 14, 2014
    Date of Patent: April 12, 2016
    Assignee: Infirst Healthcare Limited
    Inventors: Robin M. Bannister, John Brew, Richard R. Reiley, III, Wilson Caparros Wanderley
  • Patent number: 9301973
    Abstract: The invention provides methods, compositions, and dietary formulations useful for preventing or treating dermatitis, promoting healthy skin, and retarding skin aging. The methods comprise administering to an animal a therapeutically effective amount of a combination of at least two of one or more antioxidants; one or more anti-glycation agents; one or more body fat reducing agents; one or more insulin sensitivity enhancing agents; and one or more anti-inflammatory agents.
    Type: Grant
    Filed: October 21, 2011
    Date of Patent: April 5, 2016
    Assignee: Nestec S.A.
    Inventors: Yuanlong Pan, Steven Scott Hannah, Rondo Paul Middleton
  • Patent number: 9271950
    Abstract: The present specification discloses pharmaceutical compositions, methods of preparing such pharmaceutical compositions, and methods and uses of treating a chronic inflammation and/or an inflammatory disease in an individual using such pharmaceutical compositions.
    Type: Grant
    Filed: January 14, 2014
    Date of Patent: March 1, 2016
    Assignee: Infirst Healthcare Limited
    Inventors: Robin M. Bannister, John Brew, Wilson Caparros-Wanderely, Suzanne J. Dilly, Olga Pleguezeulos Mateo, Gregory A. Stoloff
  • Patent number: 9079023
    Abstract: A portable electronic device comprises illuminating unit (300) configured to illuminate extrapupillarily the skin covering a user's eye cavity with optical radiation, thus resulting in diffuse propagation of optical radiation energy to an optically sensitive tissue of the user's eye, and adapting unit (500, 510, 520, 530, 550, 560) for adapting the illuminating unit (300) to the user's head.
    Type: Grant
    Filed: April 18, 2008
    Date of Patent: July 14, 2015
    Assignee: VALKEE OY
    Inventors: Antti Aunio, Juuso Nissilä
  • Patent number: 9073832
    Abstract: Disclosed are compositions and methods for treating bacterial infections.
    Type: Grant
    Filed: March 15, 2013
    Date of Patent: July 7, 2015
    Assignee: Purdue Research Foundation
    Inventors: Cynthia Stauffacher, Mark Alfred Lipton, Mohamed Naguieb Saleem, Tim Jonathan Schmidt, Calvin Nicklaus Steussy, Jr., Victor W Rodwell
  • Publication number: 20150148320
    Abstract: Cosmetic compositions comprising salicylic acid derivatives and methods of using such compositions to impart anti-aging benefits to the skin are disclosed. The salicylic acid derivatives are believed to have modulatory activity against one or more biochemical pathways implicated in the appearance of human skin.
    Type: Application
    Filed: March 11, 2014
    Publication date: May 28, 2015
    Applicant: Avon Products, Inc.
    Inventors: Kai Xi, Sung Bin Shin, Hong Hu
  • Patent number: 9040078
    Abstract: The invention provides a method for treating a subject suffering from a disease of the central nervous system which is associated with an inflammatory response, including, inter alia, multiple sclerosis, Amyotrophic Lateral Sclerosis (ALS), meningitis, Alzheimer's disease, pain, HIV-associated dementia, stroke, traumatic brain injury, encephalomyelitis, chronic inflammatory demyelinating polyneuropathy, cerebral ischemia-induced injury or any combination thereof. This invention further provides for the use of a conjugate, or composition comprising the same, for treating the subject, wherein the conjugate comprises a lipid or phospholipid moiety bonded to a physiologically acceptable monomer, dimer, oligomer, or polymer.
    Type: Grant
    Filed: August 17, 2004
    Date of Patent: May 26, 2015
    Assignee: YISSUM RESEARCH DEVELOPMENT COMPANY OF THE HEBREW UNIVERSITY OF JERUSALEM
    Inventor: Saul Yedgar
  • Publication number: 20150140136
    Abstract: Pesticidal compositions containing plant essential oils, such as rosemary oil, wintergreen oil, etc., and methods for using same are disclosed.
    Type: Application
    Filed: June 19, 2014
    Publication date: May 21, 2015
    Inventors: Steven M. BESSETTE, A. David LINDSAY
  • Publication number: 20150140133
    Abstract: A system is described for long-term controlled release delivery of a drug or a therapeutic agent. According to the invention, one or more drugs or therapeutic agents contained in microspheres are mixed with a temperature sensitive hydrogel which is then introduced directly to the desired situs of the drug or therapeutic agent. The temperature sensitive hydrogel may also contain a drug or a therapeutic agent, for example, a pain relieving drug, for a short-term controlled release. The temperature sensitive hydrogel is in liquid state at room temperature, but upon injection, shortly becomes gelatinous. This system is particularly suitable for treatment of diseases, disorders, or conditions, for example, tumors, discogenic back pain, or arthritis, warranting localized administration of a drug or a therapeutic agent. In addition, the specification provides a method for production of a drug- or therapeutic agent-containing microspheres.
    Type: Application
    Filed: December 4, 2014
    Publication date: May 21, 2015
    Inventor: Tae-Hong Lim
  • Publication number: 20150133406
    Abstract: Control or repellency of biting arthropods, particularly biting insects, is accomplished by bringing the biting arthropods into contact with combinations of compounds identical or related to those found on human/animal skin or in plants acting synergistically with one another, or in combination with conventional repellents like DEET®, para-menthane-3,8-diol (PMD), sec-butyl-2-(2-hydroxyethyl) piperidine carboxylate (“Picaridin”), or other nitrogen containing repellents selected from amines, amides and nitrogen containing heterocyclic compounds, or any synergistic combination of DEET®, PMD, Picaridin, or other nitrogen containing repellents selected from amines, amides and nitrogen containing heterocyclic compounds.
    Type: Application
    Filed: November 13, 2014
    Publication date: May 14, 2015
    Inventor: Robert H. BEDOUKIAN
  • Patent number: 9023369
    Abstract: The invention relates to freeze-dried molded articles, containing ?50% by wt. of one or more active substances, and ?15% by wt. of one or more scaffold-forming agents, with proteins being excepted, as well as optionally one or more auxiliary substances, in each case based on the total composition of the freeze-dried molded article, whose 1% by wt. solution or suspension in water, at 20° C., has a pH value <7. Furthermore, the invention relates to methods for manufacturing these freeze-dried molded articles, the combination of such freeze-dried molded articles in kit-of-parts arrangements together with aqueous solutions, as well as the use of the freeze-dried molded articles and the kit-of-parts combinations for pharmaceutical and cosmetic application.
    Type: Grant
    Filed: April 20, 2010
    Date of Patent: May 5, 2015
    Inventors: Ralf Malessa, Claudia Elsinghorst, Fabian Kuhlmann, Uwe Wagner
  • Patent number: 9012411
    Abstract: The invention provides novel compounds and formulations of turmeric oil, fish oil, aspirin and anti-cancer drugs (paclitaxel) having anti-inflammatory, analgesic and/or anti-cancer activity.
    Type: Grant
    Filed: June 29, 2012
    Date of Patent: April 21, 2015
    Assignee: Organomed Corporation
    Inventor: James N. Jacob
  • Patent number: 9005626
    Abstract: A liquid composition suitable for topical use comprising is provided that includes a phospholipid foaming agent and at least one solvent; and a pharmaceutically acceptable active agent; wherein the liquid composition is capable of mechanically foaming without an additional propellant; and wherein upon mechanical foaming of 250 ml of the liquid composition results in a foam with a foam volume of at least about 400 ml and a foam stability wherein at least about 50% of the foam volume is still present after about 5 minutes at 25° C., as determined using a SITA foam measurement. Also provided herein are methods of making disclosed compositions and methods of use.
    Type: Grant
    Filed: July 19, 2010
    Date of Patent: April 14, 2015
    Assignee: MIKA Pharma GmbH
    Inventor: Bernd G. Seigfried
  • Publication number: 20150080352
    Abstract: The present invention describes a surprising effect of an aqueous polyurethane dispersion on the efficacy of active ingredients in the anti-acne treatment. The aqueous polyurethane dispersion was able to reduce irritation and substantially enhance efficacy of the salicylic acid and/or salicylic acid derivative in the topical anti-acne serum.
    Type: Application
    Filed: March 6, 2013
    Publication date: March 19, 2015
    Applicants: BAYER MATERIALSCIENCE LLC, BAYER INTELLECTUAL PROPERTY GMBH
    Inventors: Sophie Viala, Sebastian Doerr, Yuliya Berezkin
  • Patent number: 8980234
    Abstract: A composition in the form of an oil-in-water emulsion containing: an ester of fatty acid and of polyethylene glycol; an additional surfactant chosen from esters of C16-C22 fatty acid and of sorbitan and esters of C16-C22 fatty acid and of glycerol; a polycondensate of ethylene oxide and of propylene oxide consisting of polyethylene glycol and polypropylene glycol blocks; and an ascorbic acid compound or a salicylic acid compound. The composition has good stability, in particular after hours at 55° C. Application in caring for and making up keratinous substances.
    Type: Grant
    Filed: March 9, 2009
    Date of Patent: March 17, 2015
    Assignee: L'Oreal
    Inventor: Aldo Monello
  • Publication number: 20150071864
    Abstract: A reversely thermo-reversible hydrogel composition comprising a water soluble block copolymer comprising at least two blocks of polyethylene oxide and at least one block of polypropylene oxide, and at least one associative gelling adjuvant having water solubility less than 0.5 g/100 ml, preferably less than 0.3 g/100 ml at 20° C., and being capable of forming water soluble inter-molecular complexes with the water soluble block copolymer in water. The hydrogel composition exhibits improved gelling efficiency, enhanced solubility and/or stability for water sparely soluble and insoluble pharmaceutical agents. The hydrogel compositions are useful in a variety of pharmaceutical and cosmetic products and applications, such as esophageal, otic, vaginal, rectal, ophthalmic, treatments of disorders and imperfections of the skin, and treating and/or preventing alopecia and restoring and/or promoting hair growth.
    Type: Application
    Filed: September 22, 2014
    Publication date: March 12, 2015
    Applicant: Broda Technologies Co., Ltd.
    Inventors: Shao Xiang LU, Jeffrey LU, Letian LIU
  • Publication number: 20150064124
    Abstract: Personal care formulations containing alkyl ketal esters having the structure wherein a is 0 or an integer of 1 to 12; b is 0 or 1; R2 is a divalent C1-8 group optionally substituted with up to 5 hydroxyl groups; and R1 is C1-6 alkyl.
    Type: Application
    Filed: November 7, 2014
    Publication date: March 5, 2015
    Applicant: SEGETIS, INC.
    Inventors: Dorie J. YONTZ, Lee Richard RIETH, Nicholas MORANTE, Irwin PALEFSKY
  • Patent number: 8969390
    Abstract: The invention relates to liquid compositions which contain a) from 40 to 99.9% by weight of sorbitan monocaprylate and b) from 0.1 to 60% by weight of one or more antimicrobial substances selected from the group consisting of the components b1) to b5): b1) specific organic acids and the salts thereof, b2) specific formaldehyde donors, b3) specific isothiazolinones, b4) specific paraben esters and the salts thereof, and b5) specific pyridones and the salts thereof. The liquid compositions are suitable for the production of cosmetic, dermatological or pharmaceutical products.
    Type: Grant
    Filed: May 11, 2010
    Date of Patent: March 3, 2015
    Assignee: Clariant Finance (BVI) Limited
    Inventors: Peter Klug, Sonja Gehm, Guiseppina Kluth, Franz-Xaver Scherl, Maurice Frederic Pilz
  • Publication number: 20150050321
    Abstract: An oil in water emulsion that has a water phase and an oil phase. The water phase includes greater than about 0.5% of the salt form of a neutralized acid, the acid being preferably salicylic acid; and, from about 2% to about 0.001%, by weight of a gum. The oil in water emulsion is stable, that is, it is substantially unaltered in chemical state and physical homogeneity, upon exposure to 14 days at a temperature & humidity of about 50° C. and 60% RH. The gum is preferably xanthan gum, and the emulsion may include from about 0.01 to about 10%, of an emulsifier.
    Type: Application
    Filed: July 22, 2014
    Publication date: February 19, 2015
    Inventors: William Robert GATELY, Robert Bao Kim HA, Rebecca Ann FINLEY
  • Publication number: 20150045330
    Abstract: The present invention provides a prophylactic and/or therapeutic agent for amyotrophic lateral sclerosis, which contains an anacardic acid derivative, and a method of screening for a prophylactic and/or therapeutic drug for amyotrophic lateral sclerosis, utilizing an induced pluripotent stem cell derived from a patient with amyotrophic lateral sclerosis.
    Type: Application
    Filed: January 17, 2013
    Publication date: February 12, 2015
    Inventors: Haruhisa Inoue, Naohiro Egawa, Shiho Kitaoka, Kayoko Tsukita
  • Publication number: 20150037408
    Abstract: The present invention relates to modified release pharmaceutical compositions comprising salsalate. The invention also relates to processes for the preparation of such compositions.
    Type: Application
    Filed: October 21, 2014
    Publication date: February 5, 2015
    Inventors: Kothari Jay Shantilal, Muthaiyyan Esakkimuthu Kannan, Mistry Gaurav Navinbhai, Brij Khera
  • Patent number: 8946451
    Abstract: The invention relates to lipoic acid acylated salicylate derivatives; compositions comprising an effective amount of a lipoic acid acylated salicylate derivative; and methods for treating or preventing an metabolic disease comprising the administration of an effective amount of a lipoic acid acylated salicylate derivative.
    Type: Grant
    Filed: October 5, 2010
    Date of Patent: February 3, 2015
    Assignee: Catabasis Pharmaceuticals, Inc.
    Inventors: Jill C. Milne, Michael R. Jirousek, Jean E. Bemis, Chi B. Vu
  • Publication number: 20150010478
    Abstract: Disposable absorbent articles comprising an absorbent material and an antimicrobial composition are disclosed. The antimicrobial composition includes a carrier comprising fatty alcohol and a poly(alkyleneoxy) polymer, and an antimicrobial agent. The antimicrobial composition may be coated on to component substrates such as nonwovens and films, that are incorporated into disposable absorbent articles, such as disposable infant diapers, adult incontinence articles, feminine hygiene articles such as sanitary napkins, wound dressings, bandages, panty liners and tampons, personal care wipes and household wipes to provide odor control, and control of microbial growth.
    Type: Application
    Filed: September 9, 2014
    Publication date: January 8, 2015
    Inventors: David T. Amos, Bathsheba E. Chong Conklin, Alexis S. Statham, Michael J. Svarovsky, Leigh E. Wood
  • Publication number: 20150004232
    Abstract: Dermal delivery compositions are provided. Aspects of the dermal delivery compositions include the presence of active agent-calcium phosphate particle complexes, where these complexes include uniform, rigid, spherical nanoporous calcium phosphate particles associated with one or more active agents. Also provided are methods of using the compositions in active agent delivery applications.
    Type: Application
    Filed: April 22, 2014
    Publication date: January 1, 2015
    Applicant: Laboratory Skin Care, Inc.
    Inventor: Zahra Mansouri
  • Patent number: 8921390
    Abstract: A Medicaments for inhibiting thrombus formation contains active ingredients which are triflusal and clopidogrel bisulfate, wherein a mass ratio of triflusal to clopidogrel bisulfate is (100-650):(30-150), preferably (1-20):1, more preferably (3-6):1, and even more preferably 3:1 or 6:1.
    Type: Grant
    Filed: March 17, 2010
    Date of Patent: December 30, 2014
    Assignee: Guizhou Liansheng Pharmaceutical Co. Ltd.
    Inventor: Chunhua Su
  • Publication number: 20140348936
    Abstract: Gastroretentive controlled release vehicles may, in some embodiments, (1) comprise a polymeric matrix and agents for the treatment, prevention, and/or mitigation of a disease and/or side effect thereof and (2) have both gastroretentive properties and controlled release properties. Preferrably, the polymeric matrix may comprise ethylene copolymers, ethyl celluloses, and/or thermoplastic polyurethanes that may optionally be partially crosslinked.
    Type: Application
    Filed: December 17, 2012
    Publication date: November 27, 2014
    Inventors: Jose Reyes, Kenneth Anderson, Dale Zevotek, Nathan Reuter, J. Gregory Little, Jeffrey Haley, Vassilios Galiatsatos
  • Patent number: 8895537
    Abstract: The present specification discloses pharmaceutical compositions, methods of preparing such pharmaceutical compositions, and methods and uses of treating a cardiovascular disease in an individual using such pharmaceutical compositions.
    Type: Grant
    Filed: February 3, 2012
    Date of Patent: November 25, 2014
    Assignee: Infirst Healthcare Ltd.
    Inventors: Robin Mark Bannister, John Brew, Suzanne Jane Dilly, Gregory Alan Stoloff, Wilson Caparros-Wanderley