With A Vitamin Type Active Ingredient Patents (Class 514/168)
  • Patent number: 10548834
    Abstract: The object of the present invention is the cosmetic use via an oral route of a combination of actives comprising at least one polyunsaturated fatty acid and vitamin D, for improving the hair quality. This combination of actives may further comprise, as an additional active, vitamin E, vitamin C, a carotenoid, zinc gluconate or combinations thereof. The combination of actives is preferably applied in a cosmetic composition intended for oral administration, such as a food supplement.
    Type: Grant
    Filed: August 29, 2014
    Date of Patent: February 4, 2020
    Assignee: NUTRICOS TECHNOLOGIES
    Inventors: Carole Bru, Yann Mahe, Nathalie Piccardi
  • Patent number: 10398729
    Abstract: A method of treating Alzheimer's Disease of users comprising daily use of a lotion, the components of which are disclosed, a daily supplementation with powdered whey protein and Vitamin D, and a mild exercise component.
    Type: Grant
    Filed: February 14, 2012
    Date of Patent: September 3, 2019
    Inventor: Kenneth O. Russell
  • Patent number: 10357501
    Abstract: Methods for treating/preventing conditions associated with an increased level of eotaxin in a human with 25-hydroxyvitamin D3 (calcifediol) are provided. Optionally, vitamin D3 may be used together with 25-hydroxyvitamin D3.
    Type: Grant
    Filed: December 28, 2016
    Date of Patent: July 23, 2019
    Assignee: DSM IP ASSETS B.V.
    Inventors: Stephanie Krammer-Lukas, Elisabeth Stoecklin, Joseph Schwager, Swen Wolfram
  • Patent number: 10278980
    Abstract: Provided are nutritional supplements designed for enhancing the growth, particularly the linear growth, of pre-pubertal children with a stature measure short compared to the norm. The nutritional composition comprises an energy source, and a combination of micronutrients, and is adapted separately for the nutritional needs of male or female adolescents.
    Type: Grant
    Filed: September 21, 2015
    Date of Patent: May 7, 2019
    Assignee: NutriTeen Professionals LTD
    Inventors: Moshe Phillip, Michal Yackobovitch-Gavan, Raanan Shamir, Hadassa Bymel
  • Patent number: 10265343
    Abstract: The present invention relates to methods of co-administration of various vitamins and mineral compositions, and in a specific embodiment, said methods comprise co-administering one composition comprising vitamin A, beta carotene, B-complex vitamins, vitamin C, vitamin D3, vitamin E, iron, magnesium and zinc, and a second composition comprising omega-3 fatty acids such as DHA, to supplement the nutritional needs of individuals within physiologically stressful states; and kits provided for co-administration of various vitamin and mineral compositions, and in a specific embodiment, said kits comprise one composition comprising vitamin A, beta carotene, B-complex vitamins, vitamin C, vitamin D3, vitamin E, iron, magnesium and zinc, and a second composition comprising omega-3 fatty acids, such as DHA, to supplement the nutritional needs of individuals within physiologically stressful states.
    Type: Grant
    Filed: September 20, 2017
    Date of Patent: April 23, 2019
    Assignee: Exeltis USA, Inc.
    Inventors: John A. Giordano, Charles J. Balzer
  • Patent number: 10258980
    Abstract: The present invention relates to metal complexes and methods of synthesizing the metal complexes. The invention is further directed to pharmaceutical and/or dietary supplement composition comprising compounds synthesized as described herein.
    Type: Grant
    Filed: September 8, 2015
    Date of Patent: April 16, 2019
    Assignee: C Lab Pharma International, S.A.
    Inventors: Charles Louis Albartus Barker, Siead Zegar, Kurt Wachholder
  • Patent number: 9925161
    Abstract: Pentacyclic triterpene weight loss agents are provided herein. Also provided are pharmaceutical formulations containing a therapeutically effective amount of one or more of the weight loss agents, or pharmaceutically acceptable salts or prodrugs thereof, in combination with one or more pharmaceutically acceptable excipients. The pharmaceutical formulations can be administered to a pre-obese, obese, or morbidly obese patient to induce weight loss, reduce body fat, reduce food intake, improve glucose homeostasis, prevent obesity, or a combination thereof. The weight loss agents can also be co-administered with leptin or a leptin analog.
    Type: Grant
    Filed: July 7, 2017
    Date of Patent: March 27, 2018
    Assignees: The Children's Medical Center Corporation, The General Hospital Corporation
    Inventors: Umut Ozcan, Joseph Majzoub, Ralph Mazitschek, Isin Cakir, Serkan Cabi
  • Patent number: 9795635
    Abstract: The present invention relates to methods of co-administration of various vitamin and mineral compositions, and in a specific embodiment, said methods comprise co-administering one composition comprising vitamin A, beta carotene, B-complex vitamins, vitamin C, vitamin D3, vitamin E, iron, magnesium and zinc, and a second composition comprising omega-3 fatty acids such as DHA, to supplement the nutritional needs of individuals within physiologically stressful states; and kits provided for co-administration of various vitamin and mineral compositions, and in a specific embodiment, said kits comprise one composition comprising vitamin A, beta carotene, B-complex vitamins, vitamin C, vitamin D3, vitamin E, iron, magnesium and zinc, and a second composition comprising omega-3 fatty acids such as DHA, to supplement the nutritional needs of individuals within physiologically stressful states.
    Type: Grant
    Filed: February 29, 2016
    Date of Patent: October 24, 2017
    Assignee: Exeltis USA, Inc.
    Inventors: John A. Giordano, Charles J. Balzer
  • Patent number: 9622970
    Abstract: The present invention is to providing a new preparation including complex of a medical compound with lutein, astaxanthin and antioxidant. The new preparation includes stabilized liposome preparation, sustained release preparation and polymeric micelles preparation which used as delivery systems for lutein, astaxanthin and antioxidant. The new preparation significantly increases bioavailability of lutein and astaxanthin and uses for treatment and prevention of eyes and other disease.
    Type: Grant
    Filed: May 8, 2014
    Date of Patent: April 18, 2017
    Inventor: Yaguang Liu
  • Patent number: 9549569
    Abstract: The invention provides a composition and method for providing nutritional support to obese patients. The composition has an energy density between 0.4 and 0.9 kcal/ml and comprises a protein source which comprises at least 30% by weight whey protein and provides at least 30% of the total calories of the composition. The composition may include a carbohydrate source and a lipid source. Preferably at least 50% by weight of the protein source is whey protein. The invention further extends to use of the composition in the prevention of treatment of malnutrition in obese patients.
    Type: Grant
    Filed: October 14, 2013
    Date of Patent: January 24, 2017
    Assignee: Nestec S.A.
    Inventor: Claudia Roessle
  • Patent number: 9504712
    Abstract: The present invention relates to the use of polyunsaturated fatty acids and one or more components which have a beneficial effect on total methionine metabolism selected from the group consisting of vitamin B12 and precursors thereof, vitamin B6 and derivatives thereof, folic acid, zinc and magnesium, in the manufacture of a preparation for improving the action of receptors. This preparation is advantageously applied in patients suffering from Parkinson's disease, Huntington's chorea, epilepsy, schizophrenia, paranoia, depression, sleep disorders, impaired memory function, psychoses, dementia and ADHD.
    Type: Grant
    Filed: February 27, 2015
    Date of Patent: November 29, 2016
    Assignee: N.V. Nutricia
    Inventors: Amanda Johanne Kiliaan, Robert Johan Joseph Hageman
  • Patent number: 9220701
    Abstract: A storage stable ointment of the present invention comprises a vitamin D compound, a corticosteroid, and an N,N-di (C1-C8)alkylamino substituted, (C4-C18)alkyl(C2-C18)carboxylic ester a (C1-C4)-alkyl(C8-C22)carboxylic ester in a petrolatum ointment base, and optionally containing mineral oil and/or tocopherol. Preferably, the vitamin D compound is calcipotriene, the corticosteroid is selected from the group consisting of clobetasol propionate and betamethasone dipropionate, and the N,N-di(C1-C8) alkylamino substituted, (C4-C18)alkyl(C2-C18) carboxylic ester comprises dodecyl 2-(N,N-dimethylamino)-propionate (DDAIP).
    Type: Grant
    Filed: October 2, 2009
    Date of Patent: December 29, 2015
    Assignee: NEXMED HOLDINGS, INC.
    Inventors: William Shifeng Wei, Yiping Wang, Jianzhen Pan, Sung Hi Jo
  • Publication number: 20150136638
    Abstract: The present invention relates to a method for preparing a syrupy product comprising vitamins, said method comprising the following steps: a) inerting all the apparatuses implemented in the method b) inserting sugar syrup into said apparatuses and adding vitamins under inert atmosphere; c) adding dehydrated and deoxygenated glucose under inert atmosphere; d) deoxygenating the syrupy product formed in this way; e) packaging the syrupy product under inert atmosphere.
    Type: Application
    Filed: January 29, 2013
    Publication date: May 21, 2015
    Applicant: LaboratoiresUrgo
    Inventors: Franck Eymard, Pierre Gabiot, Romain Brenon, Michel Lamoise
  • Publication number: 20150141386
    Abstract: Poor vitamin K status is provided as an independent risk factor for allograft failure and mortality in patients who received organ transplantation and who are under immunosuppressive medication. Various forms and recommended dosages of vitamin K, optionally combined with vitamin D and/or other immunosuppressive medication, are provided to optimize the treatment of such patients resulting in decreased allograft failure and improved patient survival.
    Type: Application
    Filed: June 4, 2013
    Publication date: May 21, 2015
    Inventors: Cornelis Vermeer, Martin De Borst
  • Patent number: 8999962
    Abstract: There is disclosed herein a method of increasing bone density, maintaining bone density and/or inhibiting loss of bone density and/or reducing osteochondral defects in an animal comprising administering to an animal an effective amount of a composition containing: vitamin K1, vitamin K2 or a mixture of vitamin K1 and vitamin K2, together with a physiologically acceptable carrier, incipient and/or diluent. Various compositions including vitamin K are also disclosed.
    Type: Grant
    Filed: June 2, 2009
    Date of Patent: April 7, 2015
    Inventors: John Ray Biffin, Hubertus Leonardus Regtop
  • Publication number: 20150079198
    Abstract: The present invention relates to a method and nutritional supplement which stimulates appetite and slows metabolism of a mammal, thereby enhancing weight gain for the mammal. The method of enhancing weight gain of the mammal comprises administering to the mammal an effective amount of at least two types of alkamide or isobutylamide compound extracted from Echinacea species along with an antioxidant and optionally minerals. The nutritional supplement of the present invention comprises an antioxidant and at least two types of alkamide or isobutylamide compounds derived from Echinacea species. Minerals such as zinc and magnesium can also be added to the nutritional supplement to provide even better effect.
    Type: Application
    Filed: September 13, 2013
    Publication date: March 19, 2015
    Inventors: Travis Kurt Alvord, Tyler Stevens Alvord
  • Publication number: 20150079165
    Abstract: Methods and compositions for treating 25-hydroxyvitamin D insufficiency and deficiency in a patient are described herein. The method includes orally administering to the patient a delayed, sustained release formulation including a first ingredient selected from the group consisting of 25-hydroxyvitamin D2, 25-hydroxyvitamin D3, or a combination of 25-hydroxyvitamin D2 and 25-hydroxyvitamin D3, or it includes gradually administering to the patient a sterile intravenous formulation including a first ingredient selected from the group consisting of 25-hydroxyvitamin D2, 25-hydroxyvitamin D3, or a combination of 25-hydroxyvitamin D2 and 25-hydroxyvitamin D3.
    Type: Application
    Filed: November 19, 2014
    Publication date: March 19, 2015
    Inventors: Charles W. Bishop, Keith H. Crawford, Eric J. Messner
  • Publication number: 20150079164
    Abstract: The present disclosure relates to food supplement, dietary supplement, nutritional supplement, over-the-counter (OTC) supplement, medical food, or pharmaceutical grade supplement compositions comprising omega-3 fatty acids and vitamin D for use in improving at least one parameter associated with acne and/or eczema (dermatitis).
    Type: Application
    Filed: March 15, 2013
    Publication date: March 19, 2015
    Applicant: Pronova Biopharma Norge AS
    Inventors: David A. Fraser, Alexis Garras
  • Patent number: 8962000
    Abstract: An oil in water microemulsion or sub-micron emulsion composition for dermal delivery of at least one pharmaceutically active ingredient, is provided. The composition includes an oil phase dispersed throughout a water phase, the oil phase including at least one member selected from the group consisting of an animal oil, a mineral oil, a vegetable oil, a silane member, a siloxane, an ester, a fatty acid, a fat, a halogen compound, and an alkoxylated alcohol; and at least one lipophilic surfactant, the water phase including at least one hydrophilic surfactant, water and optionally a non-surfactant amphiphilic compound, the weight ratio of the at least one hydrophilic surfactant to the at least one lipophilic surfactant being approximately 9.0:1.0 to 2.0:3.0.
    Type: Grant
    Filed: April 30, 2013
    Date of Patent: February 24, 2015
    Assignee: Stiefel West Coast LLC
    Inventors: Maria Graziella Larm, Ronald Harding, Michael Johnston, Albert Zorko Abram, Prema Viyayakumar, Phoebe Sun
  • Patent number: 8962239
    Abstract: Methods for diagnosing, treating, and preventing catabolism-related vitamin D deficiency and related disorders, related compositions, apparatus and kits, are disclosed. A method involves measuring CYP24 expression and/or activity, or a proxy thereof such as FGF23 level, in a patient and correlating abnormally elevated CYP24 expression and/or activity with catabolism-related vitamin D deficiency or with susceptibility for catabolism-related vitamin D deficiency. In response to abnormally elevated CYP24 expression and/or activity, the method further includes administering a CYP24 inhibitor to the vitamin D deficient or at-risk patient, and preferably avoiding activation of the vitamin D binding receptor, such as by avoiding administration of active vitamin D compounds to such patients. Optionally, a vitamin D prohormone or prohormone can be administered.
    Type: Grant
    Filed: April 2, 2009
    Date of Patent: February 24, 2015
    Assignees: Opko Renal, LLC, Opko IP Holdings II, Inc.
    Inventors: P. Martin Petkovich, Christian F. Helvig, Joel Z. Melnick
  • Publication number: 20150025048
    Abstract: The present disclosure is directed to methods for enhancing, improving or increasing fertility or reproductive function. For example, the present disclosure is directed to a method for enhancing, improving, or increasing a female human's likelihood of becoming pregnant comprising: administering to the human a nutritional, dietary, or food fatty acid supplement comprising: at least 30% docosahexaenoic acid (DHA), by weight of the total fatty acids in the supplement in a form chosen from ethyl ester, free fatty acid, and triglyceride.
    Type: Application
    Filed: March 7, 2013
    Publication date: January 22, 2015
    Inventors: Mark Puder, Deepika Nehra, Bo R. Rueda
  • Publication number: 20150017260
    Abstract: A nutritional supplement composition for treating nutritional deficiencies caused by a medical condition in subjects is disclosed. The present application further discloses a method of using a nutritional supplements composition for treating a subject with complications resulting from sickle cell anemia. The method comprises administering to a subject an effective amount of the nutritional supplement.
    Type: Application
    Filed: July 28, 2014
    Publication date: January 15, 2015
    Inventors: Jacqueline M. Hibbert, Jonathan K. Stiles, Kayellen Umeakunne, Hyacinth I. Hyacinth
  • Publication number: 20140348910
    Abstract: The present invention relates to topical formulations that include lipid microcapsules formed from tocopherol, tocotrienol, or mixtures thereof; a stabilizer/surfactant component; and an aqueous component. The lipid microcapsules may be formed without the use of steroids, preservatives, initiators and/or oils. The topical formulations are capable of delivering transdermal active agent(s) such as vitamin D through the skin and into the bloodstream without the use of skin penetration enhancers. In certain embodiments, the topical formulations also able to deliver topical active agent(s) such as sun-protecting agents to the surface of the skin where they remain, while simultaneously delivering the transdermal active agent(s) through the skin and into the bloodstream.
    Type: Application
    Filed: June 29, 2012
    Publication date: November 27, 2014
    Applicant: AVIDAS PHARMACEUTICALS LLC
    Inventor: David Craig Wright
  • Patent number: 8889660
    Abstract: In one aspect of the present invention, a pharmaceutical composition for treating a metabolic disease in a mammalian subject includes a therapeutically effective amount of (R)-all-trans-13,14-dihydroretinol and a pharmaceutically acceptable carrier or diluent. In another aspect of the present invention, pharmaceutical composition for treating a metabolic disease in a mammalian subject includes a therapeutically effective amount of (S)-all-trans-13,14-dihydroretinol and a pharmaceutically acceptable carrier or diluent. In a further aspect of the present invention, a method is provided for treating a metabolic disease in a mammalian subject. The method includes administering to the subject a pharmaceutical composition comprising at least one all-trans-13,14-dihydroretinoid, all-trans-13,14-dihydroretinoid derivative, or agent capable of modulating the level of at least one all-trans-13,14-dihydroretinoid or all-trans-13,14-dihydroretinoid derivative in the subject.
    Type: Grant
    Filed: November 16, 2012
    Date of Patent: November 18, 2014
    Assignee: Case Western Reserve University
    Inventors: Krzysztof Palczewski, Radu Moise
  • Publication number: 20140274977
    Abstract: A method of treating and preventing secondary hyperparathyroidism in CKD by increasing or maintaining blood concentrations of both 25-hydroxyvitamin D and 1,25-dihydroxyvitamin D in a patient by administering 25-hydroxyvitamin D3 with or without 25-hydroxyvitamin D2 and, as necessary, 1,25-dihydroxyvitamin D2 as a Vitamin D hormone replacement therapy.
    Type: Application
    Filed: May 30, 2014
    Publication date: September 18, 2014
    Applicant: OPKO RENAL, LLC
    Inventors: Charles W. Bishop, Eric J. Messner
  • Patent number: 8728535
    Abstract: In one embodiment of the present invention, a pharmaceutically-acceptable single-dosage formulation consists essentially of about 500 mg of vitamin C; about 400 IUs of vitamin D3; about 125 IUs of vitamin E; about 25 mg of vitamin B1; about 3.4 mg of vitamin B2; about 35 mg of niacin; about 35 mg of vitamin B6; about 1.25 mg of folic acid; about 70 mcg of vitamin B12; about 5 mg of pantothenic acid; about 75 mcg of biotin; about 35 mg of magnesium; about 35 mg of zinc; about 1 mg of copper; about 125 mcg of selenium; about 150 mcg of chromium; about 10 mg of alpha lipoic acid; about 35 mg of co-enzyme Q-10; about 400 mcg of lutein; about 125 mcg of lycopene; and at least one or more excipients.
    Type: Grant
    Filed: June 19, 2012
    Date of Patent: May 20, 2014
    Assignee: Vertical Pharmaceuticals, LLC
    Inventors: Steven A. Squashic, Kevin M. Hudy, David C. Purdy
  • Publication number: 20140113886
    Abstract: A stabilized 1,25-dihydroxyvitamin D2 composition which is particularly well suited for pharmaceutical formulations, pharmaceutical formulations of the 1,25-dihydroxyvitamin D2 composition, and a method of making the purified composition by purifying a crude 1,25-dihydroxyvitamin D2 from acetone/water, are disclosed.
    Type: Application
    Filed: January 2, 2014
    Publication date: April 24, 2014
    Applicant: CYTOCHROMA INC.
    Inventor: Uttam Saha
  • Patent number: 8703174
    Abstract: A pet supplement includes a joint preserving and joint rebuilding composition comprising chicken collagen type II, glucosamine hydrochloride and chondroitin sulfate, a vitamin composition comprising vitamins C, D and K, a mineral composition comprising calcium, magnesium, zinc, copper, manganese and boron, a herbal anti-oxidant cofactor blend comprising citrus bioflavonoids, red grapes anthocyanins, turmeric rhizome, boswellia resin and fennel seed. Each of these ingredients is intimately mixed into the pet supplement and orally delivered to the pet in the form of a segment, paste or powder having a size and weight or other dosage measuring feature adjusted in accordance with the pet's weight. A synergistic action between these ingredients preserves and rebuilds the pet's joints, and is nutritionally beneficial for the pet.
    Type: Grant
    Filed: September 15, 2006
    Date of Patent: April 22, 2014
    Assignee: I did It Inc
    Inventor: Marni Markell Hurwitz
  • Patent number: 8691299
    Abstract: Disclosed is an ingestible insect repellent composition and method utilizing a mixture of vitamins and extracts of lemon, coffee and/or peppermint as active insect deterrent. The composition may be diluted for easier intake into water, juices, milk, soda, mixed drinks and other beverages. Exemplary embodiments disclosed herein may include creating a premix capable of providing up to 100% of the suggested daily intake of specific Vitamin when diluted in any appropriate beverage. Exemplary embodiments may be utilized to repel insects for hours after ingestion in both humans and animals. The exemplary embodiments may provide this repellant without the harmful effects of other chemicals and repellants.
    Type: Grant
    Filed: April 4, 2011
    Date of Patent: April 8, 2014
    Inventors: Deveral Bodden, Ana Carro
  • Publication number: 20140066415
    Abstract: Methods and compositions comprising 1,25-dihydroxyvitamin D2 are disclosed. A method for lowering or maintaining lowered serum parathyroid hormone in human patients including administering to said patients an effective amount of 1,25-dihydroxyvitamin D2 to lower or maintain lowered serum parathyroid hormone levels is disclosed. Dosage forms and dosing regimens are also disclosed.
    Type: Application
    Filed: November 11, 2013
    Publication date: March 6, 2014
    Applicant: Opko IP Holdings II, Inc.
    Inventors: P. Martin Petkovich, Charles W. Bishop, Eric J. Messner, Keith H. Crawford
  • Patent number: 8609725
    Abstract: The present invention relates to methods for the prevention and treatment of chronic inflammatory diseases, cancer, and involuntary weight loss. In the practice of the present invention patients are enterally administered HMB alone or alternatively in combination with eicosapentaenoic (20:5 ?-3), FOS, carnitine and mixtures thereof. HMB may be added to food products comprising a source of amino-nitrogen enriched with large neutral amino acids such as leucine, isoleucine, valine, tyrosine, threonine and phenylalanine and substantially lacking in free amino acids.
    Type: Grant
    Filed: January 11, 2012
    Date of Patent: December 17, 2013
    Assignee: Abbott Laboratories
    Inventors: Jeffrey H. Baxter, Anne C. Voss, Pradip Mukerji, Michael J. Tisdale
  • Patent number: 8609629
    Abstract: The present invention relates to methods of co-administration of various vitamin and mineral compositions, and in a specific embodiment, said methods comprise co-administering one composition comprising vitamin A, beta carotene, B-complex vitamins, vitamin C, vitamin D3, vitamin E, iron, magnesium and zinc, and a second composition comprising omega-3 fatty acids such as DHA, to supplement the nutritional needs of individuals within physiologically stressful states; and kits provided for co-administration of various vitamin and mineral compositions, and in a specific embodiment, said kits comprise one composition comprising vitamin A, beta carotene, B-complex vitamins, vitamin C, vitamin D3, vitamin E, iron, magnesium and zinc, and a second composition comprising omega-3 fatty acids such as DHA, to supplement the nutritional needs of individuals within physiologically stressful states.
    Type: Grant
    Filed: January 23, 2012
    Date of Patent: December 17, 2013
    Assignee: Evertt Laboratories, Inc.
    Inventors: John A. Giordano, Charles J. Balzer
  • Publication number: 20130316990
    Abstract: Animal feed with 25-hydroxy vitamin D3 added, optionally in combination with vitamin D3, improves bone strength in animals, particularly pigs.
    Type: Application
    Filed: November 23, 2012
    Publication date: November 28, 2013
    Applicant: DSM IP ASSETS B.V.
    Inventor: DSM IP ASSETS B.V.
  • Patent number: 8592392
    Abstract: A method for optimizing the health of humans according to their age and sex is disclosed wherein the method comprises administering to said humans a daily dose of a multiple antioxidant micronutrient composition comprising vitamin A (palmitate), beta-carotene (from natural d. salina), vitamin C (calcium ascorbate), vitamin D-3 (cholecalciferol), natural source vitamin E including both d-alpha tocopherol and d-alpha tocopheryl acid succinate, thiamine mononitrate, riboflavin, niacinamide ascorbate, d-calcium pantothenate, pyridoxine hydrochloride, cyanocobalamin, folic acid (folacin), d-biotin, selenium (l-seleno methionine), chromium picolinate, zinc glycinate, calcium citrate, and magnesium citrate. For persons over the age of about 51, the composition preferably further comprises one or more of co-enzyme Q10, N-acetyl cysteine, and alpha lipoic acid. Preferably, also, vitamin D is added for women over the age of about 36.
    Type: Grant
    Filed: January 11, 2005
    Date of Patent: November 26, 2013
    Assignee: Premier Micronutrient Corporation
    Inventors: Kedar N Prasad, Gerald M Haase
  • Patent number: 8563053
    Abstract: A composition and method for treating a bone condition of an animal. The composition includes a nanoformulation of active ingredients. The active ingredients include Lepidium Sativum or other Lepidium extracts, calcium, vitamin D, and antioxidants. The method for treating a bone condition includes introducing the composition into the animal.
    Type: Grant
    Filed: October 27, 2010
    Date of Patent: October 22, 2013
    Inventors: Shaker A. Mousa, Mohammed H. Qari, Mohammed S. Ardawi
  • Patent number: 8535660
    Abstract: The present invention relates to different nutritional supplements to be administered to, or taken by, pregnant women during the first, second and third trimesters of pregnancy.
    Type: Grant
    Filed: November 7, 2011
    Date of Patent: September 17, 2013
    Assignee: Argent Development Group, LLC
    Inventors: John C. Morrison, Kenneth R. Greathouse
  • Patent number: 8535659
    Abstract: The present invention relates to different nutritional supplements to be administered to, or taken by, pregnant women during the first, second and third trimesters of pregnancy.
    Type: Grant
    Filed: May 21, 2009
    Date of Patent: September 17, 2013
    Assignee: Argent Development Group, LLC
    Inventors: John C. Morrison, Kenneth R. Greathouse
  • Publication number: 20130225521
    Abstract: A micronutrient dosage unit which comprises two or more micronutrients selected from vitamin A, vitamin B2, vitamin B6, vitamin B9, vitamin B12, vitamin C, vitamin D, vitamin E, vitamin K, calcium, magnesium, zinc, boron and chromium in one or more specified ratios. This Abstract is not intended to define the invention disclosed in the specification, nor intended to limit the scope of the invention in any way.
    Type: Application
    Filed: April 9, 2013
    Publication date: August 29, 2013
    Inventor: Ralph BROWN
  • Publication number: 20130217655
    Abstract: Compositions useful for the treatment of hyperproliferative dermal diseases of the scalp. Specifically, topical gel and liquid compositions that include calcipotriol and nicotinamide in a polyethylene glycol-based carrier, for topical application to the scalp.
    Type: Application
    Filed: October 10, 2011
    Publication date: August 22, 2013
    Applicant: Dermipsor Ltd.
    Inventor: Zeev Even-Chen
  • Publication number: 20130210782
    Abstract: We disclose treating hyperglycemia in a human with 25-hydroxyyitamin D3 (calcifediol). Blood glucose is reduced to a level which is closer to normal than baseline. Vitamin D3 (cholecalciferol) may optionally be used together with 25-hydroxy vitamin D3. Forms and dosages of a pharmaceutical composition, as well as processes for manufacturing medicaments, are also disclosed.
    Type: Application
    Filed: March 15, 2013
    Publication date: August 15, 2013
    Applicant: DSM IP ASSETS B.V.
    Inventor: DSM IP ASSETS B.V.
  • Publication number: 20130178451
    Abstract: The method of treating elevated blood levels of iPTH by increasing or maintaining blood concentrations of both 25-hydroxyvitamin D and 1,25-dihydroxyvitamin D in a patient by administering, as necessary, both Vitamin D repletion and Vitamin D hormone replacement therapies, is disclosed. The blood concentrations of 25-hydroxyvitamin D are increased to and maintained at or above 30 ng/mL, and blood concentrations of 1,25-dihydroxyvitamin D are increased to or maintained within a patient's normal historical physiological range for 1,25-dihydroxyvitamin D without causing substantially increased risk of hypercalcemia, hyperphosphatemia or over suppression of plasma iPTH in the patient. The blood levels of 25-hydroxyvitamin D are maintained at or above 30 ng/mL between doses of Vitamin D repletion therapies, and the blood levels of 1,25-dihydroxyvitamin D are maintained in the patient's normal historical physiological range between doses of Vitamin D hormone replacement therapies.
    Type: Application
    Filed: November 19, 2012
    Publication date: July 11, 2013
    Applicants: PROVENTIV THERAPEUTICS, LLC, CYTOCHROMA INC.
    Inventors: CYTOCHROMA INC., PROVENTIV THERAPEUTICS, LLC
  • Patent number: 8481514
    Abstract: The present invention thus concerns a method for treating and/or preventing rickets, osteoporosis, osteomalacia, psoriasis, autoimmune diseases such as multiple sclerosis or type I diabetes, hyperparathyroidism, benign prostate hyperplasia, any type of cancer or any vitamin D relevant disease comprising administering inecalcitol at doses comprised between 1 mg/day and 100 mg/day to a human patient in need thereof.
    Type: Grant
    Filed: May 18, 2010
    Date of Patent: July 9, 2013
    Assignee: Hybrigenics SA
    Inventors: Rémi Delansorne, Jean-François Dufour-Lamartinie
  • Publication number: 20130172299
    Abstract: The field of the present invention relates to novel and improved therapies for treatment of complications associated with impaired renal function. More specifically, the present invention relates to evaluating the effects of a novel renal multivitamin on Vitamin D levels, EPO dose, inflammatory (e.g., C-reactive protein) and other biomarkers in an end stage renal disease (ESRD) population on hemodialysis (HD).
    Type: Application
    Filed: July 19, 2012
    Publication date: July 4, 2013
    Inventor: Ray Chow
  • Patent number: 8460641
    Abstract: An oil-in-water microemulsion or sub-micron emulsion composition for dermal delivery of at least one pharmaceutically active ingredient, comprising: a first part including at least one occlusive agent and one or more lipophilic surfactants dispersed throughout a second part including water and at least one hydrophilic surfactant, and a non-surfactant amphiphilic type compound, pharmaceutically active ingredient, and water. It has been found that if a non-surfactant amphiphilic type compound is added together with the second part as would conventionally be the case, a microemulsion or sub-micron emulsion is not formed, by adding the so called third part, phase assembly occurs at a lower temperature than would be expected and moreover, this phase appears to assist in maintaining the microemulsion or sub-micron emulsion characteristics of the formulation during storage at normal temperatures.
    Type: Grant
    Filed: August 31, 2005
    Date of Patent: June 11, 2013
    Assignee: Stiefel Research Australia Pty Ltd
    Inventors: Maria Graziella Larm, Ronald Harding, Michael Johnston, Albert Zorko Abram, Prema Vijayakumar, Phoebe Sun
  • Publication number: 20130137663
    Abstract: Methods and compositions for reducing serum parathyroid levels in, for example, chronic kidney disease patients are disclosed. In these methods, an effective amount of a modified release formulation of 25-hydroxy vitamin D is orally administered to a patient suffering from secondary hyperparathyroidism to lower the patient's serum intact parathyroid hormone (iPTH) level, while avoiding a surge in serum total 25-hydroxy vitamin D.
    Type: Application
    Filed: March 29, 2011
    Publication date: May 30, 2013
    Inventors: Eric J. Messner, P. Martin Petkovich, Jay A. White, Samir P. Tabash, Joel Z. Melnick, Charles W. Bishop
  • Patent number: 8449867
    Abstract: An oil in water microemulsion or sub-micron emulsion composition for dermal delivery of at least one pharmaceutically active ingredient, is provided. The composition includes an oil phase dispersed throughout a water phase, the oil phase including at least one member selected from the group consisting of an animal oil, a mineral oil, a vegetable oil, a silane member, a siloxane, an ester, a fatty acid, a fat, a halogen compound, and an alkoxylated alcohol; and at least one lipophilic surfactant, the water phase including at least one hydrophilic surfactant, water and optionally a non-surfactant amphiphilic compound, the weight ratio of the at least one hydrophilic surfactant to the at least one lipophilic surfactant being approximately 9.0:1.0 to 2.0:3.0.
    Type: Grant
    Filed: June 25, 2009
    Date of Patent: May 28, 2013
    Assignee: Stiefel Research Australia Pty Ltd
    Inventors: Maria Graziella Larm, Ronald Harding, Michael Johnston, Albert Zorko Abram, Prema Vijayakumar, Phoebe Sun
  • Publication number: 20130052274
    Abstract: Nutritional compositions and methods of making and using the nutritional compositions are provided. In a general embodiment, the present disclosure provides a nutritional composition including exogenous vitamin K2. The nutritional compositions may further include an additional component selected from the group consisting of phosphorus, magnesium, zinc, iron, copper, manganese, calcium, vitamin D, osteopontin and combinations thereof.
    Type: Application
    Filed: September 1, 2010
    Publication date: February 28, 2013
    Applicant: Nestec S.A.
    Inventors: Douglas Richard Bolster, Zamzam Kabiry Roughead
  • Patent number: 8338394
    Abstract: A pharmaceutical composition for treating a metabolic disease in a mammalian subject includes a therapeutically effective amount of all-trans-13,14-dihydroretinoid, all-trans-13,14-dihydroretinoid derivative, or agent capable of modulating the level of at least one all-trans-13,14-dihydroretinoid or all-trans-13,14-dihydroretinoid derivative in the subject.
    Type: Grant
    Filed: October 9, 2007
    Date of Patent: December 25, 2012
    Assignee: Case Western Reserve University
    Inventors: Krzysztof Palczewski, Radu A. Moise
  • Publication number: 20120277180
    Abstract: Provided herein are methods and systems for identifying one or more cofactors such as vitamins for individuals based on the genetic makeup of the individual by detecting the presence or absence of at least one genetic variant, determining a predisposition to cofactor remediable condition, generating a personalized nutritional advice plan based on the genetic variant. Also provided herein are formulations of cofactors determined by the genetic make-up of the individual and methods of determining and producing these formulations.
    Type: Application
    Filed: September 30, 2010
    Publication date: November 1, 2012
    Applicants: VITAPATH GENETICS, INC, THE REGENTS OF THE UNIVERSITY OF CALIFORNIA
    Inventors: Nicholas Marini, Jasper Rine, Dennis Austin Gilbert, Bruce Cohen
  • Patent number: 8273380
    Abstract: A beverage for minimizing or reducing jet lag symptoms preferably includes vitamin B3, vitamin B5, vitamin B6, vitamin B12, vitamin D, zinc, calcium, iodine, magnesium, manganese, ginseng, ginkgo biloba, grape seed extract, Echinacea extract and water. A method for minimizing or reducing jet lag symptoms including ingestion of the beverage by a traveler, one hour prior to a flight, and/or during the flight, and/or after a flight.
    Type: Grant
    Filed: May 19, 2009
    Date of Patent: September 25, 2012