3-benzazepines (including Hydrogenated) Patents (Class 514/217.01)
Benzene ring bonded directly to ring carbon of the seven-membered hetero ring (Class 514/217.02)
  • Acetylenic aryl sulfonamide and phosphinic acid amide hydroxamic acid TACE inhibitors
    Publication number: 20010056088
    Abstract: Hydroxamic acids having the formula 1
    Type: Application
    Filed: June 14, 2001
    Publication date: December 27, 2001
    Applicant: American Cyanamid Company
    Inventors: Jeremy I. Levin, James M. Chen
  • Substituted isoquinoline derivatives and their use as anticonvulsants
    Publication number: 20010025045
    Abstract: This invention relates to substituted isoquinoline derivatives and their use as anticonvulsants.
    Type: Application
    Filed: April 22, 2001
    Publication date: September 27, 2001
    Applicant: SmithKline Beecham p.l.c.
    Inventors: Peter David Edwards, John David Harling, Mervyn Thompson
  • 1,2,4,5-Tetrahydro-benzo[D]azepin derivatives
    Patent number: 6218385
    Abstract: The present invention is concerned with 1,2,4,5-tetrahydro-benzo[d]azepin derivatives as well as with their pharmaceutically acceptable salts in their racemic and optically active form, which compounds are antagonists at metabotropic glutamate receptors and therefore useful for the treatment of diseases related to these receptors.
    Type: Grant
    Filed: August 1, 2000
    Date of Patent: April 17, 2001
    Assignee: Hoffmann-La Roche Inc.
    Inventors: Geo Adam, Alfred Binggeli, Hans-Peter Märki, Vincent Mutel, Maurice Wilhelm, Wolfgang Wostl