1,3,5-thiadiazines Patents (Class 514/223.8)
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Patent number: 11632959Abstract: Methods, systems, and kits are provided for in situ seed treatment with liquid crop benefit compositions at planting in furrow.Type: GrantFiled: December 8, 2016Date of Patent: April 25, 2023Assignee: FMC CorporationInventor: Timothy M. Martin
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Patent number: 9549557Abstract: The present invention relates to novel active compound combinations comprising at least one known compound of the formula (I) in which X, R1 to R4, A, n, Y, and m are as defined in the description, and at least one further known active compound from the class of the fiproles, which combinations are highly suitable for controlling animal pests such as insects and unwanted acarids.Type: GrantFiled: April 14, 2014Date of Patent: January 24, 2017Assignee: BAYER CROPSCIENCE AKTIENGESELLSCHAFTInventors: Koen Van Den Eynde, Wolfgang Thielert
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Patent number: 9549554Abstract: The present invention relates to novel active compound combinations comprising at least one known compound of the formula (I) in which X, R1 to R4, A, n, Y, and m are as defined in the description, and at least one further known active compound from the class of avermectins/milbemycins, which combinations are highly suitable for controlling animal pests such as insects and unwanted acarids.Type: GrantFiled: April 14, 2014Date of Patent: January 24, 2017Assignee: BAYER CROPSCIENCE AKTIENGESELLSCHAFTInventors: Koen Van Den Eynde, Wolfgang Thielert
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Patent number: 9173394Abstract: The present invention relates to novel active substance combinations which contain firstly at least one known compound of the formula (I) in which R1 and A have the meanings given in the description, and secondly at least one further known active substance from the class of the macrolides, the carboxylates or other classes, and which are highly suitable for controlling animal pests such as insects and undesired acarids.Type: GrantFiled: September 13, 2008Date of Patent: November 3, 2015Assignee: BAYER INTELLECTUAL PROPERTY GMBHInventors: Heike Hungenberg, Peter Jeschke, Robert Velten, Wolfgang Thielert
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Publication number: 20150111746Abstract: A pesticidal composition comprises a synergistically effective amount of an inhibitor of chitin biosynthesis, type 1 compound and a pesticide selected from N-(3-chloro-1-(pyridin-3-yl)-1H-pyrazol-4-yl)-N-ethyl-3-((3,3,3-trifluoropropyl)thio)propanamide (I), N-(3-chloro-1-(pyridine-3-yl)-1H-pyrazol-4-yl)-N-ethyl-3-((3,3,3-trifluoropropyl)sulfinyl)propanamide (II), or any agriculturally acceptable salt thereof. A method of controlling pests comprises applying the pesticidal composition near a population of pests. A method of protecting a plant from infestation and attack by pests comprises contacting the plant with the synergistic pesticidal composition.Type: ApplicationFiled: October 17, 2014Publication date: April 23, 2015Inventors: Luis E. Gomez, Ricky Hunter, Mike Shaw, Tony K. Trullinger, Mary E. Kubiszak, John Herbert
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Patent number: 9012444Abstract: Tumor growth and metastases in cancer patients are inhibited by administration of a combination therapy including effective amounts of 5-Fluorouracil and a methylol transfer agent such as taurolidine, taurultam or mixtures thereof.Type: GrantFiled: March 21, 2011Date of Patent: April 21, 2015Assignee: Ed. Geistlich Soehne AG fuer Chemische IndustrieInventors: H. Paul Redmond, Rolf W. Pfirrmann
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Publication number: 20150030501Abstract: A solid body of dazomet for use in internal remedial treatments of wood and methods of applying such solid bodies to wooden structures and manufacturing such solid bodies. The solid bodies can be easily transported and inserted into treatment holes in utility poles, wooden pilings, and other wooden structures, delivering a precise, accurate dose of insecticide and fungicide that combats internal decay in the wood.Type: ApplicationFiled: July 25, 2013Publication date: January 29, 2015Applicant: Osmose Utilities Services, Inc.Inventors: Thomas Pope, Douglas J. Herdman, Peter Tham
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Publication number: 20140303045Abstract: Systems and methods for controlling microbial growth and/or activity in a gas field fluid or oil field fluid are provided, comprising: a) adding a first biocide component to the gas field fluid or oil field fluid in an amount effective to control microbial growth and/or activity; and b) after a delay, adding a second biocide component to the gas field fluid or oil field fluid.Type: ApplicationFiled: April 4, 2014Publication date: October 9, 2014Applicant: Kemira OyjInventors: Scott Campbell, Angela Marie Johnson
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Patent number: 8821898Abstract: The invention relates to novel insecticidal active compound combinations comprising, firstly, cyclic ketoenols or other insecticidally active compounds and, secondly, further insecticidally active compounds from the group of the anthranilamides, which combinations are highly suitable for controlling animal pests, such as insects and unwanted acarides.Type: GrantFiled: November 20, 2004Date of Patent: September 2, 2014Assignee: Bayer CropScience AGInventors: Christian Funke, Reiner Fischer, Rüdiger Fischer, Heike Hungenberg, Wolfram Andersch, Wolfgang Thielert, Anton Kraus
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Publication number: 20140221298Abstract: The present invention provides an agricultural and horticultural fungicidal composition including a compound A which is at least one selected from a nitrogen-containing heterocyclic compound having a specific structure including a compound represented by the formula (1), and a salt thereof, and a compound B which is at least one selected from the group of specific pesticidally active compounds: in the formula (1), X each independently represents a halogeno group or a C1 to 6 alkyl group; n represents the number of X(s) and is an integer of 0 to 6; and X? represents a halogeno group; and R1, R2 and R3 each independently represent a C1 to 6 alkyl group or a hydroxyl group.Type: ApplicationFiled: September 24, 2012Publication date: August 7, 2014Inventor: Raito Kuwahara
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Publication number: 20140141972Abstract: This invention pertains to methods for protecting a propagule or a plant grown therefrom from invertebrate pests comprising contacting the propagule or the locus of the propagule with a biologically effective amount of a compound of Formula I, its N-oxide or an agriculturally suitable salt thereof wherein A and B and R1 through R8 are as defined in the disclosure. This invention also relates to propagules treated with a compound of Formula I and compositions comprising a Formula I compound for coating propagules.Type: ApplicationFiled: January 27, 2014Publication date: May 22, 2014Applicant: E I DU PONT NEMOURS AND COMPANYInventors: RICHARD ALAN BERGER, Isaac Billy Annan, George Philip Lahm, John Lindsey Flexner, Thomas Paul Selby, Thomas Martin Stevenson
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Publication number: 20140140973Abstract: This invention pertains to a method for controlling lepidopteran, homopteran, hemipteran, thysanopteran and coleopteran insect pests comprising contacting the insects or their environment with an arthropodicidally effective amount of a compound of Formula I, its N-oxide or an agriculturally suitable salt thereof wherein A and B and R1 through R8 are as defined in the disclosure. This invention further relates to a bezoxazinone compound of Formula 10 wherein R4 through R8 are as defined in the disclosure, useful for preparation of a compound of Formula I.Type: ApplicationFiled: January 27, 2014Publication date: May 22, 2014Applicant: E I DU PONT DE NEMOURS AND COMPANYInventors: GEORGE PHILIP LAHM, Stephen Frederick McCann, Kanu Maganbhai Patel, Thomas Paul Selby, Thomas Martin Stevenson
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Publication number: 20130189228Abstract: This invention provides compounds of Formula 1, N-oxides and suitable salts thereof wherein R1 is Me, Cl, Br or F; R2 is F, Cl, Br, C1-C4 haloalkyl or C1-C4 haloalkoxy; R3 is F, Cl or Br; R4 is H; C1-C4 alkyl, C3-C4 alkenyl, C3-C4 alkynyl, C3-C5 cycloalkyl, or C4-C6 cycloalkylalkyl, each optionally substituted with one substituent selected from the group consisting of halogen, CN, SMe, S(O)Me, S(O)2Me, and OMe; R5 is H or Me; R6 is H, F or Cl; and R7 is H, F or Cl. Also disclosed are methods for controlling an invertebrate pest comprising contacting the invertebrate pest or its environment with a biologically effective amount of a compound of Formula 1, an N-oxide thereof or a suitable salt of the compound (e.g., as a composition described herein).Type: ApplicationFiled: March 11, 2013Publication date: July 25, 2013Applicant: E I DU PONT DE NEMOURS AND COMPANYInventor: E I DU PONT DE NEMOURS AND COMPANY
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Publication number: 20130172260Abstract: Catheters used for medical treatment, e.g., hemodialysis are filled with a locking solution, usually heparin between treatments. To prevent infections, antimicrobial or antibiotic substances have been used as locking solution alone or in combination with antithrombotic substances. It has been found that these locking solutions are rapidly washed out from the catheter tip. The invention describes a thixotropic gel that can be used as locking solution. Beneficial substances, e.g., antimicrobial or antibiotic substances can be added to the gel. A preferred antimicrobial substance is taurolidine alone or in combination with salicylic acid or one of its salts.Type: ApplicationFiled: July 23, 2012Publication date: July 4, 2013Inventor: Hans-Dietrich Polaschegg
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Publication number: 20130089622Abstract: This document discloses molecules having the following formula (“Formula I”):Type: ApplicationFiled: November 14, 2012Publication date: April 11, 2013Applicant: Dow AgroSciences LLCInventor: Dow AgroSciences LLC
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Publication number: 20130005712Abstract: The present invention relates to a composition for noxious organisms-controlling agent having a synergistic effect and a method for using said composition, which comprises, as active ingredients thereof, one or more compounds selected from the phthalamide derivatives represented by general formula (I) being useful as an insecticide or acaricide and one or more compounds selected from the compounds having insecticidal, acaricidal or nematocidal activity: wherein R1, R2 and R3 may be the same or different and each represent hydrogen atom, C3-C6 cycloalkyl, -A1--Qp, etc., each of X and Y may be the same or different and represents hydrogen atom, halogen atom, etc., n is an integer of 1 to 4, m is an integer of 1 to 5, and each of Z1 and Z2 represents O or S.Type: ApplicationFiled: September 11, 2012Publication date: January 3, 2013Inventors: Kazuyuki Sakata, Masayuki Morimoto, Hiroshi Kodama, Tetsuyosi Nishimatsu
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Publication number: 20120322765Abstract: The present invention provides a composition having an excellent controlling activity on plant disease. The composition comprising the compound represented by the formula (1) and one or more inorganic fungicidal compound selected from the group (A) shows an excellent controlling activity on a plant disease. group (A): a group consisting of fludioxonil, pencycuron, ametoctradin, chloroneb, chlorothalonil, oxine-copper, cyflufenamid, dichlofluanid, dicloran, diethofencarb, dinocap, dithianon, edifenphos, fenaminosulf, fentin, fluazinam, fluoroimide, flusulfamide, flutianil, fosetyl-Al, hydrargaphen, iprobenfos, metrafenon, milneb, penflufen, phosdiphen, phthalide, prothiocarb, pyrazophos, sedaxane, silthiofam, spiroxamine, tebufloquin, and tolyfluanid.Type: ApplicationFiled: March 2, 2011Publication date: December 20, 2012Applicant: SUMITOMO CHEMICAL COMPANY, LIMITEDInventors: So Kiguchi, Soichi Tanaka, Mayuko Ozawa, Atsushi Iwata
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Publication number: 20120316062Abstract: The present invention relates to synergistic mixtures comprising, as active components, one insecticidal compound I selected from the group of insect growth regulators comprising chitin synthesis inhibitors, moulting disruptors and ecdysone receptor agonists; and one fungicidal compound II selected from the group of strobilurine fungicides in synergistic effective amounts.Type: ApplicationFiled: December 6, 2010Publication date: December 13, 2012Applicant: BASF SEInventor: Markus Gewehr
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Publication number: 20120316157Abstract: The present invention provides a composition having an excellent controlling activity on plant disease. The composition comprising the compound represented by the formula (1) and one or more heterocyclic fungicidal compound selected from the group (A) shows an excellent controlling activity on a plant disease.Type: ApplicationFiled: March 2, 2011Publication date: December 13, 2012Applicant: SUMITOMO CHEMICAL COMPANY, LIMITEDInventors: So Kiguchi, Soichi Tanaka, Mayuko Ozawa, Atsushi Iwata
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Publication number: 20120283099Abstract: The invention disclosed in this document concerns controlling planthoppers.Type: ApplicationFiled: May 4, 2012Publication date: November 8, 2012Applicant: DOW AGROSCIENCES LLCInventors: Agamananda Roy, Sanjoy Kundu, Suresh Ramachandran
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Patent number: 8304390Abstract: A method of treatment for preventing or reducing tumor growth in liver of a patient includes administering to the patient an effective about of taurolidine, taurultam or a mixture thereof, so as to prevent or reduce the tumor growth in the patient.Type: GrantFiled: February 9, 2006Date of Patent: November 6, 2012Assignee: Ed. Geistlich Soehne AG fuer Chemische IndustrieInventor: Rolf W. Pfirrmann
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Patent number: 8173645Abstract: Compounds are provided for use with glucokinase that comprise the formula: wherein the variables are as defined herein. Also provided are pharmaceutical compositions, kits and articles of manufacture comprising such compounds; methods and intermediates useful for making the compounds; and methods of using said compounds.Type: GrantFiled: March 20, 2008Date of Patent: May 8, 2012Assignee: Takeda San Diego, Inc.Inventors: Zacharia Cheruvallath, Jun Feng, Prasuna Guntupalli, Stephen L. Gwaltney, Joanne Miura, Mark Sabat, Mingnam Tang
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Publication number: 20120077675Abstract: The present invention relates to novel active compound combinations comprising, firstly, at least one known compound of the formula (I) in which R1 and A have the meanings given in the description and, secondly, at least one further known active compound from the class of the chitin synthesis inhibitors, the molting hormone agonists or other classes, which combinations are highly suitable for controlling animal pests such as insects and unwanted acarids.Type: ApplicationFiled: March 25, 2009Publication date: March 29, 2012Applicant: BAYER CROPSCIENCE AGInventors: Heike Hungenberg, Peter Jeschke, Robert Velten, Wolfgang Thielert
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Publication number: 20110293533Abstract: Disclosed are mixtures and compositions for controlling invertebrate pests relating to combinations comprising (a) 3-bromo-N-[4-chloro-2-methyl-6-[(methylamino)carbonyl]phenyl]-1-(3-chloro-2-pyridinyl)-1H-pyrazole-5-carboxamide, and its N-oxides, and suitable salts thereof and a component (b) wherein the component (b) is at least one compound or agent selected from neonicotinoids, cholinesterase inhibitors, sodium channel modulators, chitin synthesis inhibitors, ecdysone agonists, lipid biosynthesis inhibitors, macrocyclic lactones, GABA-regulated chloride channel blockers, juvenile hormone mimics, ryanodine receptor ligands, octopamine receptor ligands, mitochondrial electron transport inhibitors, nereistoxin analogs, pyridalyl, flonicamid, pymetrozine, dieldrin, metaflumizone, biological agents, and suitable salts of the foregoing.Type: ApplicationFiled: August 11, 2011Publication date: December 1, 2011Applicant: E.I. DU PONT NEMOURS AND COMPANYInventors: Isaac Billy Annan, John Lindsey Flexner, Hector Eduardo Portillo, George Philip Lahm, Thomas Paul Selby, Thomas Martin Stevenson
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Publication number: 20110218104Abstract: Disclosed are pesticide compositions that utilize biodiesel as a solvent. The disclosed compositions may be utilized for controlling pests, such as nematodes and weeds, and for enhancing growth of plants.Type: ApplicationFiled: March 3, 2010Publication date: September 8, 2011Applicant: AUBURN UNIVERSITYInventors: R. Rodriguez-Kabana, Lee J. Simmons, C. Robert Taylor
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Publication number: 20110124588Abstract: The novel active compound combinations comprising compounds of the formulae (I) and (II) have very good insecticidal and acaricidal properties.Type: ApplicationFiled: April 28, 2009Publication date: May 26, 2011Applicant: Bayer Cropscience AGInventors: Peter Jeschke, Reiner Fischer, Wolfram Andersch, Heike Hungenberg
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Patent number: 7910580Abstract: Tumor growth and metastases in cancer patients are inhibited by administration of a combination therapy including effective amounts of 5-Fluorouracil and a methylol transfer agent such as taurolidine, taurultam or mixtures thereof.Type: GrantFiled: January 18, 2008Date of Patent: March 22, 2011Assignee: Ed. Geistlich Soehne AG Fuer Chemische IndustrieInventors: H. Paul Redmond, Rolf W. Pfirrmann
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Publication number: 20110053919Abstract: The novel active compound combinations comprising a compound of the formula (I) or (II) and the active compounds (1) to (6) listed in the description have very good insecticidal and acaricidal properties.Type: ApplicationFiled: July 6, 2007Publication date: March 3, 2011Applicant: BAYER CROPSCIENE AGInventors: Reiner Fischer, Wolfram Andersch, Thomas König, Anton Kraus, Emmanuel Salmon, Heike Hungenberg
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Publication number: 20110052656Abstract: A process has been found which increases the efficiency and effectiveness of introducing antimicrobial compounds into complex biofilm matrices through the use of liposome carriers, thereby removing the biofouling in industrial water bearing systems, including piping, heat exchanges, condensers, filtration systems and fluid storage tanks. According to one embodiment of the invention, antimicrobial compound containing liposomes are added to water systems prone to biofouling and biofilm formation. The liposomes, being similar in composition to microbial membranes or cells, are readily incorporated into the existing biofilm. Once the antimicrobial compound containing liposomes become entrained with the biofilm matrix, the decomposition or programmed disintegration of the liposome proceeds. Thereafter, the biocidal aqueous core is released to react directly with the biofilm encased microorganisms.Type: ApplicationFiled: September 28, 2010Publication date: March 3, 2011Applicant: GENERAL ELECTRIC COMPANYInventors: Wilson Kurt Whitekettle, Gloria Jean Tafel, Qing Zhao, Linna Wang, Dorothy Reynolds, Paul Frail, Juan Jiang, David M. Polizzotti
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Publication number: 20110045104Abstract: The present invention constitutes new 3-[1-(3-haloalkyl)triazolyl]phenyl sulphide derivatives of the formula (I) in which A1, A2, B0, B1, B2, B3, R1, R2 and n are as defined in the description, to their use as acaricides and insecticides for controlling animal pests, and to processes for preparing them.Type: ApplicationFiled: August 19, 2010Publication date: February 24, 2011Applicant: Bayer CropScience AGInventors: Bernd Alig, Stefan Antons, Reiner Fischer, Norbert Lui, Adeline Köhler, Arnd Voerste
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Publication number: 20100311677Abstract: The novel active compound combinations comprising compounds of the formulae (I) and (II) have very good insecticidal and acaricidal properties.Type: ApplicationFiled: September 9, 2008Publication date: December 9, 2010Applicant: Bayer CropScience AGInventors: Reiner Fischer, Wolfram Andersch, Heike Hungenberg
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Publication number: 20100298137Abstract: The present invention relates to novel active compound combinations comprising at least one known compound of the formula (I) in which R is as defined in the description, and at least one further known active compound from the classes of the benzenedicarboxamides, the macrolides, the diacylhydrazines, the carboxylates or another class. Combinations of the present invention are highly suitable for controlling animal pests such as insects and unwanted acarids.Type: ApplicationFiled: March 19, 2007Publication date: November 25, 2010Applicant: BAYER CROPSCIENCE AGInventors: Heike Hungenberg, Peter Jeschke, Rüdiger Fischer, Robert Velten, Thomas Schenke, Wolfram Andersch, Wolfgang Thielert
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Publication number: 20100239678Abstract: The present invention is directed to attaching drugs 11 and other functional groups to surfaces of nano-sized diamond particles (NDs) 20 to enhance their efficacy. The method involves hydrating a plurality of nanodiamond (ND) particles 20 having a plurality of carbon chain surface molecules 23 on its surface. Cations 40 are embedded within the lattice structure 21 of the surface molecules 23 of the ND particles 20. The embedded cations 40 attract anions that cause crystalline growth. The anion form of drug molecules 11 are then grown on the crystal to cause the NDs 20 to be coated such that the active sites of said drug molecules 11 point away from the ND particle 20 exposing them for enhanced activity and enhanced drug efficacy. The efficacy of antimicrobial drugs 11, as well as other drugs 11 are enhanced by their attachment to the NDs 20.Type: ApplicationFiled: June 7, 2010Publication date: September 23, 2010Inventor: Ali RAZAVI
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Publication number: 20100120616Abstract: The invention relates to pesticidal mixtures comprising as active compounds 1) at least one cyanosulfoximine compound I of the formula (I) wherein R1, R2 and G are defined in the description; and 2) at least one active compound II selected from a group A comprising acteylcholine esterase inhibitors, GABA-gated chloride channel antagonists, sodium channel modulators, nicotinic acetylcholine receptor agonists/antagonists, chloride channel activators, juvenile hormone mimics, compounds affecting the oxidative phosphorylation, inhibitors of the chitin biosynthesis, moulting disruptors, inhibitors of the MET, voltage-dependent sodium channel blockers, inhibitors of the lipid synthesis and other compounds as defined in the description, in synergistically gistically effective amounts. The invention relates further to methods and use of these mixtures for combating insects, arachnids or nematodes in and on plants, and for protecting such plants being infested with pests and also for protecting seeds.Type: ApplicationFiled: March 18, 2008Publication date: May 13, 2010Inventors: Delphine Breuninger, Henricus Maria Martinus Bastiaans, Wolfgang Von Deyn, Juergen Langewald
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Publication number: 20100056469Abstract: Pesticidal mixtures comprising aminothiazoline compounds The present invention relates to pesticidal mixtures comprising as active compounds 1) at least one aminothiazoline compound I of the Formula (I) wherein R1, R2, R3, R4, R5 and R6 are defined in the description; and 2) at least one active compound II selected from a group A comprising acetylcholine esterase inhibitors, GABA-gated chloride channel antagonists, sodium channel modulators, nicotinic acetylcholine receptor agonists/antagonists, chloride channel activators, juvenile hormone mimics, compounds affecting the oxidative phosphorylation, inhibitors of the chitin biosynthesis, moulting disruptors, inhibitors of the MET, voltage-dependent sodium channelblockers, inhibitors of the lipidsynthesis and other compounds as defined in the description, in synergistically effective amounts.Type: ApplicationFiled: February 22, 2008Publication date: March 4, 2010Inventors: Jürgen Langewald, Markus Kordes, Deborah L. Culbertson, Douglas D. Anspaugh
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Publication number: 20090162453Abstract: There is a harmful organism that cannot be controlled or is difficult to be controlled with the use of a single agent of a compound represented by the general formula (1) according to the invention, an insecticide, a miticide or a fungicide. Accordingly, an object of the invention is to provide a composition for preventing harmful organisms for efficiently controlling such a harmful organism.Type: ApplicationFiled: July 27, 2005Publication date: June 25, 2009Applicant: MITSUI CHEMICALS, INCInventors: Nobuyuki Kawahara, Michikazu Nomura, Hidenori Daido
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Patent number: 7371743Abstract: The present invention relates to new substituted carboxylic acid amides of general formula wherein A, B and R1 to R5 are defined as in claim 1, the tautomers, the enantiomers, the diastereomers, the mixtures thereof and the salts thereof, particularly the physiologically acceptable salts thereof with inorganic or organic acids or bases, which have valuable properties.Type: GrantFiled: February 11, 2005Date of Patent: May 13, 2008Assignee: Boehringer Ingelheim International GmbHInventors: Henning Priepke, Kai Gerlach, Roland Pfau, Norbert Hauel, Iris Kauffmann-Hefner, Georg Dahmann, Herbert Nar, Sandra Handschuh, Wolfgang Wienen, Annette Schuler-Metz
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Patent number: 7361653Abstract: The present invention relates to a composition for noxious organisms-controlling agent having a synergistic effect and a method for using said composition, which comprises, as active ingredients thereof, one or more compounds selected from the phthalamide derivatives represented by general formula (I) being useful as an insecticide or acaricide and one or more compounds selected from the compounds having insecticidal, acaricidal or nematocidal activity: wherein R1, R2 and R3 may be the same or different and each represent hydrogen atom, C3-C6 cycloalkyl, -A1-Qp, etc., each of X and Y may be the same or different and represents hydrogen atom, halogen atom, etc., n is an integer of 1 to 4, m is an integer of 1 to 5, and each of Z1 and Z2 represents O or S.Type: GrantFiled: April 16, 2002Date of Patent: April 22, 2008Assignee: Nihon Nohyaku Co., LtdInventors: Kazuyuki Sakata, Masayuki Morimoto, Hiroshi Kodama, Tetsuyosi Nishimatsu
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Patent number: 7345039Abstract: Tumor growth and metastases in cancer patients are inhibited by administration of a combination therapy including effective amounts of 5-Fluorouracil and a methylol transfer agent such as taurolidine, taurultam or mixtures thereof.Type: GrantFiled: September 12, 2003Date of Patent: March 18, 2008Assignee: Ed. Geistlich Soehne AG fuer chemische IndustrieInventors: H. Paul Redmond, Rolf W. Pfirrmann
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Patent number: 7217706Abstract: This invention relates to new propanolamine derivatives or salts thereof represented by the following formula [I]: Wherein each symbol is as defined in the specification or salts thereof which have gut selective sympathomimetic, anti-ulcerous, anti-pancreatitis, lipolytic, anti-urinary incontinence and anti-pollakiuria activities, to processes for the preparation thereof, to a pharmaceutical composition comprising the same and to a method for the prevention and/or treatment diseases indicated in the specification to a human being or an animal.Type: GrantFiled: February 14, 2002Date of Patent: May 15, 2007Assignee: Astellas Pharma Inc.Inventors: Kiyoshi Taniguchi, Minoru Sakurai, Naoaki Fujii, Kumi Hosoi, Yasuyo Tomishima, Hisashi Takasugi, Hajime Sogabe, Hirofumi Ishikawa, Naomi Hanioka
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Patent number: 7195773Abstract: A pesticidal composition comprising a pesticidally effective amount of at least one of a pyridic compound of the formula (I) or it salt and at least one of other pesticides: wherein Y is a haloalkyl group, m is 0 or 1, and Q is or a substituted or unsubstituted heterocyclic group, (wherein X is an oxygen atom or a sulfur atom, R1 and R2 are respectively independently a hydrogen atom, a substituted or unsubstituted alkyl group, a substituted or unsubstituted alkenyl group, a substituted or unsubstituted alkynyl group, a substituted or unsubstituted cycloalkyl group, and the like.Type: GrantFiled: October 22, 2001Date of Patent: March 27, 2007Assignee: Ishihara Sangyo Kaisha, Ltd.Inventors: Masayuki Morita, Mitsugu Iwasa
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Publication number: 20040259863Abstract: The invention relates to the use of type 4 phosphodiesterase inhibitors (PDE IV inhibitors) to treat diseases and to combinations of PDE IV inhibitors with other drugs.Type: ApplicationFiled: April 30, 2004Publication date: December 23, 2004Inventors: Hans-Michael Eggenweiler, Michael Wolf
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Publication number: 20040242568Abstract: Compounds, pharmaceuticals, kits and methods are provided for use with DPP-IV and other S9 proteases that comprise a compound comprising the formula: 1Type: ApplicationFiled: March 24, 2004Publication date: December 2, 2004Applicant: Syrrx, Inc.Inventors: Jun Feng, Stephen L. Gwaltney, Stephen W. Kaldor, Jeffrey A. Stafford, Michael B. Wallace, Zhiyuan Zhang
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Publication number: 20040242569Abstract: Novel quaternary ammonium compounds of the formula 1Type: ApplicationFiled: April 13, 2004Publication date: December 2, 2004Applicant: Pfizer Inc.Inventors: Patrick James Lennon, Dominique Francoise Bonafoux, Sergey Gregory Wolfson
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Publication number: 20040220181Abstract: A method of treatment for preventing or inhibiting growth of cancer cells utilizes an antineoplastic composition including an antineoplastic-effective amount of a methylol transfer agent (MTA) in combination with biodegradable adhesive capable of adhering to tissue of a living subject.Type: ApplicationFiled: March 26, 2004Publication date: November 4, 2004Applicant: Ed. Geistlich Soehne AG fuer chemische IndustrieInventors: Ruediger Stendel, Rolf W. Pfirrmann
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Publication number: 20040198724Abstract: Compounds, compositions and methods are provided which are useful in the treatment of diseases through the modulation of potassium ion flux through voltage-dependent potassium channels. More particularly, the invention provides quinazolinone, compositions and methods that are useful in the treatment of central or peripheral nervous system disorders (e.g., migraine, ataxia, Parkinson's disease, bipolar disorders, trigeminal neuralgia, spasticity, mood disorders, brain tumors, psychotic disorders, myokymia, seizures, epilepsy, hearing and vision loss, Alzheimer's disease, age-related memory loss, learning deficiencies, anxiety and motor neuron diseases) and as neuroprotective agents (e.g., to prevent stroke and the like) by modulating potassium channels associated with the onset or recurrence of the indicated conditions.Type: ApplicationFiled: December 23, 2003Publication date: October 7, 2004Applicant: ICAgen, Inc.Inventors: Grant A. McNaughton-Smith, James B. Thomas, George S. Amato
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Publication number: 20040176360Abstract: The invention provides a method of inhibiting tumor growth in a mammal by, administering to the mammal composition containing taurolidine, taurultam, or a biologically active derivative thereof. The composition is administered to directly contact a tumor cell at a dose sufficient to induce cell death by apoptosis.Type: ApplicationFiled: March 8, 2004Publication date: September 9, 2004Inventors: Paul Calabresi, James Darnowski
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Publication number: 20040161428Abstract: Conjugates of transferrin or transcobalamin with anti-protozoan drugs are useful in the treatment of protozoan infections. Suitable anti-protozoan drugs include apoptosis inducing compounds, a cytotoxic antibiotic, an alkalating agent, a plant toxin, and a bacteria mutant toxin. Transferrin or transcobalamin is preferably coupled to the anti-protozoan drug by means of glutaraldehyde.Type: ApplicationFiled: November 17, 2003Publication date: August 19, 2004Inventor: W. Page Faulk
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Publication number: 20040087579Abstract: Tumor growth and metastases in cancer patients are inhibited by administration of a combination therapy including effective amounts of 5-Fluorouracil and a methylol transfer agent such as taurolidine, taurultam or mixtures thereof.Type: ApplicationFiled: September 12, 2003Publication date: May 6, 2004Applicant: Ed. Geistlich Soehne fuer Chemische IndustrieInventors: H. Paul Redmond, Rolf W. Pfirrmann
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Patent number: 6683028Abstract: The invention relates to novel guanidine derivatives of the formula (I) in which A, R1, R2, R3 and Z are as defined in the description, to a process for their preparation and to their use for controlling animal pests.Type: GrantFiled: August 17, 2001Date of Patent: January 27, 2004Assignee: Bayer AktiengesellschaftInventors: Klaus Wagner, Christoph Erdelen, Andreas Turberg, Norbert Mencke, Olaf Hansen