Abstract: Pharmaceutical compositions comprising a compound of formula (I) and at least one other anthelmintically active compound, being an avermectin or a milbemycin, are useful in the treatment of helminthiasis. In formula (I): R is optionally substituted phenyl, C.sub.3-8 cycloalkyl, C.sub.5-8 cycloalkenyl, C.sub.1-8 straight or branched chain alkyl, C.sub.2-8 straight or branched alkenyl, a 5- or 6-membered heterocyclyl, or optionally substituted phenyl C.sub.1-4 alkyl; each of Y and Z, which may be the same or different, is oxygen or sulfur; and X is a bond, a methylene group (--CH.sub.2 --), or oxygen.
Abstract: Multicomponent agent or kit for preparing the sulpho-conjugated form of pyridino, pyrimidino or triazino N-oxide compounds and method of use.The present invention relates to a multicomponent agent or kit for preparing the sulpho-conjugated form of pyridino, pyrimidino or triazino N-oxide compounds,comprising at least one compound of the pyridino, pyrimidino or triazino N-oxide type, on the one hand,and a sulphating agent, on the other hand.
Type:
Grant
Filed:
December 12, 1991
Date of Patent:
November 1, 1994
Assignee:
L'Oreal
Inventors:
Quintino Gaetani, Andre Rougier, Albert Duranton, Michel Hocquaux
Abstract: Compounds of the formula ##STR1## wherein X is an anion selected from the group consisting of phosphate, borate and molybdate groups, and a method for making these compounds. The compounds are useful in the control of microorganisms in aqueous systems and in the inhibition of corrosion of metal surfaces in contact with aqueous systems.
Type:
Grant
Filed:
April 28, 1993
Date of Patent:
October 18, 1994
Assignee:
Buckman Laboratories International, Inc.
Abstract: Microbicidal compositions comprising one or more 3-isothiazolones and 1-methyl-3,5,7-triaza-1-azoniatricyclo(3.3.1.1)decane chloride in synergistic amounts, methods, and articles are disclosed.
Abstract: Disclosed are the use of hexamethylenetetramine as a stabilizer for 3-isothiazolones under basic conditions, i.e. above pH 7.0, and compositions comprising HMT and 3-isothiazolones.
Abstract: The invention relates to synergistic antimicrobial and biocidal compositions comprising 5-chloro-2-methyl-4-isothiazolin-3-one and 2-methyl-4-isothiazolin-3-one and one or more commercial biocides for more effective, and broader control of microorganisms in various industrial systems.
Abstract: A method of preserving an aqueous system which is susceptible to microbiological degradation, comprising the step of adding to the system a compound having the formula ##STR1## wherein X is an anion selected from the group consisting of sulfate, acetate and citrate groups, and wherein the compound is added in an amount sufficient to inhibit the growth and proleferation of at least one microogranism in the aqueous system.The compounds 1-methyl-3,5,7-triaza-1-azoniatricyclodecane acetate and 1-methyl-3,5,7-triaza-1-azoniatricyclodecane citrate, and a method for preparing these compounds comprising the reaction of ammonium citrate, or ammonium acetate, with methylamine, formaldehyde and ammonia in an aqueous medium.
Type:
Grant
Filed:
March 29, 1988
Date of Patent:
April 24, 1990
Assignee:
Buckman Laboratories International, Inc.
Abstract: A method of preserving an aqueous system which is susceptible to microbiological degradation, comprising the step of adding to the system a compound having the formula ##STR1## wherein the compound is added in an amount sufficient to inhibit the growth and proliferation of at least one microorganism in the aqueous system.The compound 1-methyl-3,5,7-triaza-1-azoniatricyclodecane triiodide and a method for preparing same comprising the substitution of triiodide anion for a monohalide anion in an aqueous medium.
Type:
Grant
Filed:
November 4, 1988
Date of Patent:
January 9, 1990
Assignee:
Buckman Laboratories International, Inc.
Abstract: A broad spectrum preservative composition which comprises (a) a formaldehyde donor and (b) a halopropynyl compound; formulations containing such compositions, particularly personal care and household products; and a method of inhibiting the growth of microorganisms which includes contacting said microorganisms with the preservative composition.
Abstract: The present invention is directed to a synergistic antimicrobial admixture comprising 2-bromo-2-bromomethylglutaronitrile and a formaldehyde donor.
Abstract: Compounds of the formula: ##STR1## wherein X is oxygen or sulfur; Z is oxygen or sulfur; R is pyridyl optionally substituted with 1 to 3 substituents independently selected from halogen, lower alkyl or lower alkoxy optionally substituted with 1 to 3 of the same or different halogen atoms or nitro; R.sup.1 is lower alkyl; and R.sup.2 is a 5- or 6-membered heterocyclic ring containing 1 to 3 ring nitrogens and the remainder of the ring atoms carbon atoms, a quinoline ring or a phenyl ring, all optionally substituted with 1 to 3 substituents independently selected from halogen, trihalomethyl, lower alkyl or lower alkoxy are fungicidal.
Abstract: The present invention relates to iodopropargyl-ammonium salts of the formula (I) ##STR1## in which R, R.sup.1, R.sup.2 and X.sup..phi. have the meanings given in the description.They are obtained, for example, by reacting tertiary amines with an iodopropargyl halide. In a second reaction step, the halogen anion can be exchanged for other anions, such as phosphate and sulphate. The iodopropargylammonium salts of the formula (I) are distinguished by high activity as pest-combating agents, in particular by a fungicidal as well as bactericidal activity.
Type:
Grant
Filed:
May 2, 1983
Date of Patent:
June 4, 1985
Assignee:
Bayer Aktiengesellschaft
Inventors:
Hans-Georg Schmitt, Paul Reinecke, Wilfried Paulus, Hermann Genth, Walter Radt
Abstract: Quaternary ammonium salts formed by the reaction of hexamethylenetetramine with carboxylic acids and esters, amides and nitriles substituted in the alpha position by chlorine or bromine are preservatives for aqueous solutions, emulsions, and suspensions which are susceptible to microbiological degradation.