At 3-position Patents (Class 514/355)
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Publication number: 20130150319Abstract: A harmful arthropod control composition comprising flonicamid, tricyclazole, and one or more plant disease control compounds selected from the group consisting of flutolanil, pencycuron and kasugamycin.Type: ApplicationFiled: August 8, 2011Publication date: June 13, 2013Applicant: SUMITOMO CHEMICAL COMPANY, LIMITEDInventors: Norihisa SAKAMOTO, Emiko SAKAMOTO
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Publication number: 20130143832Abstract: A harmful arthropod control composition comprising flonicamid, one or more insect growth regulator compounds selected from Group (A), and one or more sheath blight disease control compounds selected from Group (B): Group (A): a group consisting of methoxyfenozide, tebufenozide, and chromafenozide; Group (B): a group consisting of flutolanil, pencycuron, N-[2-(1,3-dimethylbutyl)phenyl]-5-fluoro-1,3-dimethyl-1H-pyrazole-4-carboxamide, furametpyr and validamycin A, and having an excellent control effect on harmful arthropods.Type: ApplicationFiled: August 8, 2011Publication date: June 6, 2013Applicant: SUMITOMO CHEMICAL COMPANY, LIMITEDInventors: Norihisa Sakamoto, Emiko Sakamoto
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Publication number: 20130129646Abstract: The present invention relates to the cosmetic, dermatological or pharmaceutical (therapeutic) use of compounds of formula (I) or a cosmetically acceptable salt of a compound of formula (I) or a mixture containing two or more of these compounds or the salts thereof wherein R1 denotes hydrogen or an organic radical having 1 to 14 carbon atoms, R2 denotes an organic radical having 1 to 14 carbon atoms, and wherein optionally R1 and R2 are covalently bonded to one another, preferably so that a 3 to 8 membered ring is formed, for the lightening of skin and/or hair. The invention further relates to compositions and cosmetic, dermatological or pharmaceutical preparations (compositions) comprising one or more compounds of formula (I) suitable for lightening human skin and/or hair and corresponding methods.Type: ApplicationFiled: May 25, 2010Publication date: May 23, 2013Inventors: Gabriele Vielhaber, Heiko Oertling, Karin Schaper, Claudia Gömann, Rahim Brodhage
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Publication number: 20130131124Abstract: The present invention relates to O-CYCLOPROPYLCYCLOHEXYL-CARBOXANILIDES derivatives of formula (I); their process of preparation, their use as fungicide, particularly in the form of fungicide compositions, and methods for the control of phytopathogenic fungi, notably of plants, using these compounds or compositions.Type: ApplicationFiled: June 1, 2011Publication date: May 23, 2013Applicant: BAYER INTELLECTUAL PROPERTY GMBHInventors: Jörg Nico Greul, Jürgen Benting, Peter Dahmen, Ulrike Wachendorff-Neumann
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Publication number: 20130123287Abstract: Providing a novel control agent for soft rot and a novel control method for the same. A compound having no antibacterial activity against Erwinia carotovora but having a control activity against fungi on soil surface, specifically containing, as the active ingredient, a fungicide comprising any of a strobilurin compound such as azoxystrobin and kresoxim-methyl, an azole compound such as triflumizol, cyazofamid, amisulbrom, and thiophanate-methyl, a carboxamide compound such as penthiopyrad and boscalid, a sulfonamide compound such as flusulfamide, an organic chlorine compound such as chlorothalonil, a dicarboximide compound such as pro-cymidone and iprodione, a phenylpyrrole compound such as fludioxonil, an anilinopyrimidine compound such as mepanipyrim, and a guanidine compound such as iminoctadine is the control agent for plant soft rot, which is applied to plant cultivation soil.Type: ApplicationFiled: July 21, 2011Publication date: May 16, 2013Applicant: ISHIHARA SANGYO KAISHA, LTD.Inventors: Koji Sugimoto, Hiroyuki Hayashi
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Publication number: 20130121937Abstract: Provided is a composition including, as an active ingredient, at least one selected from the group consisting of amines, amides and polyols. The cosmetic composition has an effect of preventing aging and may be applied in various industrial fields, including cosmetics.Type: ApplicationFiled: June 22, 2011Publication date: May 16, 2013Inventors: Hyeon Chung Kim, Hyun Hee Kim, Sung Il Park, Youn Joon Kim, Sang Hoon Han
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Patent number: 8440704Abstract: This invention relates to a composition containing quercetin, vitamin B3, and vitamin C. Also disclosed is a method of using the composition for enhancing physical or mental performance or treating various diseases or disorders.Type: GrantFiled: December 16, 2009Date of Patent: May 14, 2013Assignee: Quercegen Pharmaceuticals LLCInventor: Thomas Christian Lines
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Patent number: 8435563Abstract: Monolayer, bilayer and trilayer solid dosage forms of a combination of valsartan, amlodipine and hydrochlorothiazide are made.Type: GrantFiled: January 3, 2012Date of Patent: May 7, 2013Assignee: Novartis Pharmaceuticals CorporationInventors: Yu Cao, Yatindra Joshi, Ping Li, Madhusudhan Pudipeddi, Alan E Royce, Robert F Wagner, Jiahao Zhu
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Publication number: 20130109655Abstract: This invention relates to a method of mitigating side effects of non-steroidal anti-inflammatory drugs, specifically to administration of a pyridine derivative to mitigate and/or prevent prostaglandin e2 reducing side effects of non-steroidal anti-inflammatory drugs. Also provided is the use of a pyridine derivative in the preparation of a medicament for the reduction of said side effects of non-steroidal anti-inflammatory drugs, and a pharmaceutical composition comprising a non-steroidal anti-inflammatory drug and a pyridine derivative.Type: ApplicationFiled: October 31, 2011Publication date: May 2, 2013Inventors: Serghei Gargaun, Ana Gargaun
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Patent number: 8431600Abstract: Use of carboxamides of the formula (I) in which A, R1, M, Q and R are as defined in the description for controlling certain rust fungi, such as soya bean rust and coffee rust, in crop protection.Type: GrantFiled: May 26, 2006Date of Patent: April 30, 2013Assignee: Bayer CropScience AGInventors: Ralf Dunkel, Hans-Ludwig Elbe, Herbert Gayer, Jörg Nico Greul, Ulrike Wachendorff-Neumann, Peter Dahmen, Ingo Wetcholowsky, Haruko Sawada, Hiroyuki Hadano
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Publication number: 20130085064Abstract: The present invention relates to pesticidal mixtures comprising a component A and a component B, wherein component A is a compound of formula (I) wherein A1, A2, R1, R2, R3, R4 and R5 are as defined in claim 1 and one of Y1 and Y2 is S, SO or SO2 and the other is CH2 and component B is an insecticide or nematicidal biological agent as defined in claim 1. The present invention also relates to methods of using said mixtures for the control of pests.Type: ApplicationFiled: February 3, 2011Publication date: April 4, 2013Applicant: SYNGENTA CROP PROTECTION LLCInventors: Patrik Hoegger, Ana Cristina Dutton, Max Angst, Jérôme Yves Cassayre
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Publication number: 20130058878Abstract: Geranylgeranyl-2-propanol compound (GGP) having the following formula (I) is proposed for use according to the present invention as a cosmetic active compound for the prevention and treatment of aging of skin and its appendages. The GGP has a protective action against oxidative stress and free radical, on telomeres and on mitochondria and its activity. In particular, GGP can be used for the treatment of wrinkles, fine lines and visible discontinuities of skin, for the treatment pigmentation disorders.Type: ApplicationFiled: April 7, 2011Publication date: March 7, 2013Applicant: SEDERMAInventors: Arnaud Fournial, Philippe Mondon, Olivier Peschard
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Patent number: 8389500Abstract: The present invention relates to compounds that are sodium channel inhibitors and to their use in the treatment of various disease states, including cardiovascular diseases and diabetes. In particular embodiments, the structure of the compounds is given by Formula (IA) or (IB): as further described herein. The invention also relates to methods for the preparation of the compounds, and to pharmaceutical compositions containing such compounds.Type: GrantFiled: October 28, 2009Date of Patent: March 5, 2013Assignee: Gilead Sciences, Inc.Inventors: Matthew Abelman, Elfatih Elzein, Robert Jiang, Rao Kalla, Tetsuya Kobayashi, Xiaofen Li, Thao Perry, Jeff Zablocki
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Publication number: 20130052173Abstract: A method for limiting the growth of microorganisms in a biomass that can he used for, or is the result of, the production of biofuels by treating said biomass with a compound selected from the group constituted by menadione, menadione derivatives and mixtures thereof.Type: ApplicationFiled: July 2, 2010Publication date: February 28, 2013Inventor: Paolo Alberto Manzotti
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Patent number: 8383653Abstract: Compounds are disclosed which inhibit SIR2 base exchange more than deacetylation, thus enhancing SIR2 deacetylation activity. Methods of using the compounds for enhancing SIR2 deacetylation activity and increasing longevity of an organism are also disclosed. Methods for screening for compounds that enhance SIR2 deacetylation activity and increase longevity of an organism are additionally disclosed.Type: GrantFiled: June 30, 2004Date of Patent: February 26, 2013Assignee: Albert Einstein College of Medicine of Yeshiva UniversityInventors: Vern L. Schramm, Anthony A. Sauve
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Patent number: 8378114Abstract: An N-2-(hetero)arylethylcarboxamide derivative represented by the formula (I) wherein R1 and R2 are each independently a hydrogen atom etc., R3 and R4 are each independently a hydrogen atom etc., each Y is independently a halogen atom; a (C1-C6)alkyl group optionally substituted by halogen atom(s) etc., n is an integer of 1 to 5, A is a specific substituted cyclic group, E is C—H; C—Y (Y is as defined above); or a nitrogen atom, a salt thereof, and a pest controlling agent containing the derivative or salt as an active ingredient show superior performance as compared to the prior art technique, and are is useful particularly as plant disease controlling agents or nematocides having a broad control spectrum at a low dose.Type: GrantFiled: March 20, 2007Date of Patent: February 19, 2013Assignee: Nihon Nohyaku Co., Ltd.Inventors: Masatsugu Oda, Yoshihiro Matsuzaki, Koji Tanaka, Eiji Takizawa, Motohiro Hasebe, Nobutaka Kuroki, Akiyuki Suwa, Kenji Oshima
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Publication number: 20130040998Abstract: Fluorinated deacetylase inhibitors of the general formulae (I), (II), and (III): and pharmaceutically acceptable salts thereof, as described herein, are useful as inhibitors of histone deacetylases or other deacetylases, and thus are useful for the treatment of various diseases and disorders associated with acetylase activity as described herein (e.g., cancer, neurodegenerative diseases, inflammatory diseases).Type: ApplicationFiled: January 5, 2011Publication date: February 14, 2013Applicants: Dana-Farber Cancer Institute, Inc., President and Fellows of Harvard CollegeInventors: James Elliot Bradner, Ralph Mazitschek
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Publication number: 20130040968Abstract: Provided is an oil or fat composition, including a vitamin B1 derivative or a salt thereof at a content of 44 to 8,000 ppm in terms of thiamine and having a hydroxyl value of 9 to 100 mg-KOH/g, in which the content C (ppm) of the vitamin B1 derivative or the salt thereof in terms of thiamine and the hydroxyl value X (mg-KOH/g) satisfy a relationship of the following expression (1): [Ln(C/143)]/X?0.044 (1), where Ln represents a natural logarithm.Type: ApplicationFiled: April 7, 2011Publication date: February 14, 2013Applicant: KAO CORPORATIONInventor: Masao Shimizu
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Patent number: 8372825Abstract: Skin compositions comprising, hydrocortisone; allantoin; and a water-based vehicle that is essentially free of petroleum jelly, mineral oil and wax; and related method for protecting, healing and/or soothing the skin comprising: applying an effective amount of a cosmetic preparation selected from the group consisting of hand cream, foot cream, body cream, lip cream, lip gloss, lip stick, gel, balm and lotion to the skin surface; wherein said cosmetic preparation includes a skin composition made of hydrocortisone; allantoin; and a water-based vehicle that is essentially free of petroleum jelly, mineral oil and wax; and said effective amount is enough to protect, heal and/or soothe the skin surface.Type: GrantFiled: August 13, 2009Date of Patent: February 12, 2013Inventor: Norman Turkowitz
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Patent number: 8372889Abstract: The subject invention provides materials and methods for modulating a variety of biological factors to treat biological conditions associated with the factors. In one embodiment of the invention, a cysteamine compound is administered to a patient to treat hypercholesterolemia and/or complications associated with hypercholesterolemia. In another embodiment, a cysteamine compound is administered to a patient to prevent the onset of diabetes in an at-risk patient and/or treat or prevent the onset of diabetes-associated complications.Type: GrantFiled: November 30, 2010Date of Patent: February 12, 2013Assignee: Omega Biopharma (I.P.3) LimitedInventors: Bill Piu Chan, Gary Kwan Po Wong, Jinxian Xu, Francis Chi
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Publication number: 20130035359Abstract: Disclosed are pharmaceutical and cosmetic compositions containing aromatic aldehyde compounds. Some of the disclosed compositions are useful as topical therapeutics for treating inflammatory dermatologic conditions. Some of the compositions are useful in transdermal and other systemic dose forms for treating other inflammatory conditions in mammals.Type: ApplicationFiled: October 11, 2012Publication date: February 7, 2013Inventors: Charles R. ENGLES, Bryan FULLER, Brian Keith PILCHER
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Publication number: 20130018020Abstract: The present invention relates to a melanin production inhibitor containing, as active ingredients, tranexamic acid and nicotinic acid amide, which inhibits the formation of skin melanocytes, and to a cosmetic composition which contains the melanin production inhibitor as an active ingredient and has the effects of reducing liver spots, blemishes, freckles and post-inflammatory hyperpigmentation, improving skin tone and texture and whitening the skin.Type: ApplicationFiled: March 30, 2011Publication date: January 17, 2013Applicant: AMOREPACIFIC CORPORATIONInventors: Hong Ju Shin, Do Hoon Kim, Jeong Hwan Kim, Hyun Ju Koh, Won Seok Park
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Publication number: 20130012536Abstract: The present invention provides compounds of Formula I useful as modulators of ABC transporter activity, or a pharmaceutically acceptable salt thereof, wherein RB, n, B, RC, RD, RE, A, and Z are described generally and in classes and subclasses below. The present invention also provides pharmaceutical compositions, methods and kits associated with Formula I, useful for as modulators, and for the treatments of disease and disease conditions associated with ABC transporter proteins.Type: ApplicationFiled: June 27, 2012Publication date: January 10, 2013Applicant: VERTEX PHARMACEUTICALS INCORPORATEDInventors: Sara S. Hadida Ruah, Mark Miller, Ashvani Singh, Matthew Hamilton, Peter D.J. Grootenhuis
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Patent number: 8349877Abstract: Ternary fungicidal compositions comprising as active components 1) boscalid, 2) chlorothalonil and 3) at least one active compound III, selected from groups A) to F): A) azoles; B) strobilurins; C) carboxamides; D) heterocyclic compounds; E) carbamates; F) other fungicides; in a synergistically effective amount, methods for controlling phytopathogenic harmful fungi using compositions of boscalid, chlorothalonil and at least one active compound III, the use of boscalid and chlorothalonil with at least one active compound III for preparing such compositions, and also agents and seed comprising such compositions.Type: GrantFiled: September 25, 2008Date of Patent: January 8, 2013Assignee: BASF SEInventors: Horst Dieter Brix, Daniel Ebersold, Martin Semar, Jens Bruns, Michael Vonend
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Publication number: 20120328526Abstract: The present invention provides a method of treating a mammal having a neuropathophysiological condition, comprising the step of administering to the mammal in need of such treatment a compound selected from nicotinamide or salts or prodrugs thereof, nicotinamide mononucleotide or salts or prodrugs thereof, nicotinamide adenine dinucleotide or salts or prodrugs thereof, nicotinamide riboside nicotinamide or salts or prodrugs thereof, phosphoribosyltransferase, or combinations thereof. Further provided is a method for treating a mammal having a neuropathophysiological condition or suspected to develop said neuropathophysiological condition, comprising the step of administering to said mammal an inhibitor of CD38 NAD+ glycohydrolase activity.Type: ApplicationFiled: June 26, 2012Publication date: December 27, 2012Inventor: Tibor Kristian
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Publication number: 20120329799Abstract: The present invention provides a composition having an excellent controlling activity on plant disease. The composition comprising the compound represented by the formula (1) and one or more carboxamide fungicidal compound selected from the group (A) shows an excellent controlling activity on a plant disease. Group (A): a group consisting of thifluzamide, oxadixyl, pencycuron, benalaxyl-M, fenhexamid, furametpyr, isopyrazam, isotianil, mepronil, tecloftalam, boscalid, fluopyram, fluopicolide, carpropamid, diclocymet, mandipropamid, dimethomorph, flumorph, penthiopyrad, and bixafen.Type: ApplicationFiled: March 2, 2011Publication date: December 27, 2012Applicant: SUMITOMO CHEMICAL COMPANY, LIMITEDInventors: So Kiguchi, Soichi Tanaka, Mayuko Ozawa, Atsushi Iwata
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Publication number: 20120322654Abstract: The present invention relates to a mixture, comprising the succinate dehydrogenase inhibitor boscalid and at least one insecticidally active compound II selected from groups A) to D) as defined in the description in a synergistically effective amount, and to compositions comprising these mixtures.Type: ApplicationFiled: March 2, 2011Publication date: December 20, 2012Applicant: BASF SEInventor: Markus Gewehr
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Publication number: 20120322831Abstract: Novel small molecule compounds for reduction of A? 42 production and for treatment of Alzheimer's Disease and other neurodegenerative disorders, methods of making them and pharmaceutical compositions containing them are described.Type: ApplicationFiled: January 22, 2011Publication date: December 20, 2012Applicant: KAREUS THERAPEUTICS SAInventors: Venkateswarlu Akella, Uday Saxena, Anji Reddy Kallam
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Publication number: 20120315329Abstract: Embodiments of the present invention relate generally to siloxane surface-modified hydrogel microparticles and pastes, methods for their preparation, and uses thereof for delivery of personal care and healthcare active ingredients, as well as agricultural active ingredients.Type: ApplicationFiled: February 17, 2011Publication date: December 13, 2012Applicant: Dow Corning CorporationInventors: Dongchan Ahn, James Thompson
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Publication number: 20120316066Abstract: The present invention provides diacylhydrazine ligands and chiral diacylhydrazine ligands for use with ecdysone receptor-based inducible gene expression systems. Thus, the present invention is useful for applications such as gene therapy, large scale production of proteins and antibodies, cell-based screening assays, functional genomics, proteomics, metabolomics, and regulation of traits in transgenic organisms, where control of gene expression levels is desirable. An advantage of the present invention is that it provides a means to regulate gene expression and to tailor expression levels to suit the user's requirements.Type: ApplicationFiled: December 2, 2011Publication date: December 13, 2012Applicant: Intrexon CorporationInventors: Robert Eugene HORMANN, Bing Li
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Publication number: 20120316197Abstract: This invention relates to a compound with EP4 antagonistic activity, or a pharmaceutically acceptable salt with EP4 receptor antagonistic activities, which is useful in the treatment of immune disease or allergy. This invention also relates to a compound of formula (I), (II), (III), (IV), (Va) or (Vb), or a pharmaceutically acceptable salt thereof with EP4 receptor antagonistic activities, which is useful in the treatment of immune disease or allergy. This invention also relates to a pharmaceutical composition for the treatment of immune disease or allergy which comprises a therapeutically effective amount of a compound of formula (I), (II), (III), (IV), (Va) or (Vb), or a pharmaceutically acceptable salt thereof.Type: ApplicationFiled: February 22, 2011Publication date: December 13, 2012Applicant: RAQUALIA PHARMA INC.Inventors: Kiyoshi Kanazawa, Kazuhiko Nonomura, Takako Okumura, Shinichi Koizumi
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Publication number: 20120309623Abstract: Provided in various embodiments are surface-modified hydrogels and hydrogel microparticles, methods for their preparation, and uses thereof for delivery of personal care and healthcare active ingredients, and agricultural active ingredients. In some embodiments, such hydrogels and hydrogel microparticles comprise surface coatings that are resistant to solvent washing and can act as barriers for the migration of water and/or water-compatible alcohols and actives soluble therein.Type: ApplicationFiled: February 17, 2011Publication date: December 6, 2012Inventors: Dongchan Ahn, James Thompson
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Publication number: 20120309724Abstract: In one aspect, the invention relates to compounds having the formula: where R1, R2, R3, X, R4, R5, and R6 are as defined in the specification, or a pharmaceutically acceptable salt thereof. These compounds have neprilysin inhibition activity. In another aspect, the invention relates to pharmaceutical compositions comprising such compounds; methods of using such compounds; and process and intermediates for preparing such compounds.Type: ApplicationFiled: May 18, 2012Publication date: December 6, 2012Applicant: THERAVANCE, INC.Inventors: Melissa Fleury, Roland Gendron, Adam D. Hughes, Jane Schmidt
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Publication number: 20120295907Abstract: The present invention relates to bis-amide derivatives of formula (I), to processes and intermediates for preparing them, to methods of using them to control insect, acarine, nematode and mollusc pests, and to insecticidal, acaricidal, nematicidal and molluscicidal compositions comprising them.Type: ApplicationFiled: April 14, 2010Publication date: November 22, 2012Applicant: SYNGENTA CROP PROTECTION, LLCInventors: Peter Maienfisch, Christopher Richard Ayles Godfrey, Pierre Joseph Marcel Jung, Ottmar Franz Hueter, Peter Renold
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Publication number: 20120295922Abstract: The present invention provides methods for treating and/or preventing mucostitis with one or more compounds, or pharmaceutically acceptable salts thereof, disclosed herein, or compositions comprising the same.Type: ApplicationFiled: May 15, 2012Publication date: November 22, 2012Applicant: POLYMEDIX, INC.Inventors: Richard W. Scott, Bozena Korczak
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Patent number: 8309608Abstract: The present invention relates to the use of compounds which enhance the transcription of endothelial nitric oxide synthase (eNOS) for treating stem and progenitor cells in the cell therapy of patients with ischemic heart diseases such as coronary heart disease or ischemic cardiomyopathy. Treatment of such cells which are isolated from bone marrow, for example, with an eNOS transcription enhancer prior to their administration improves their functional activity and ameliorates neovascularization of the heart and cardiac regeneration.Type: GrantFiled: November 2, 2004Date of Patent: November 13, 2012Assignee: Sanofi-Aventis Deutschland GmbHInventors: Andreas Zeiher, Stefanie Dimmeler, Christopher Heeschen, Hartmut Ruetten
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Publication number: 20120283226Abstract: A dermatological or cosmetic composition for skin care which includes the salt of an ?-hydroxy acid, ?-hydroxy acid, poly hydroxy acid or bionic acid in combination with niacinamide.Type: ApplicationFiled: August 31, 2010Publication date: November 8, 2012Applicant: RECKITT BENCKISER HEALTHCARE INTERNATIONAL LIMITEDInventors: Carolyn Buckley, Stuart Jackson, Tony Rawlings
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Patent number: 8304551Abstract: The invention relates to fatty acid niacin conjugates; compositions comprising an effective amount of a fatty acid niacin conjugate; and methods for treating or preventing an metabolic disease comprising the administration of an effective amount of a fatty acid niacin conjugate.Type: GrantFiled: August 31, 2010Date of Patent: November 6, 2012Assignee: Catabasis Pharmaceuticals, Inc.Inventors: Jill C. Milne, Michael R. Jirousek, Jean E. Bemis, Chi B. Vu
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Patent number: 8304552Abstract: The invention relates to fatty acid niacin conjugates; compositions comprising an effective amount of a fatty acid niacin conjugate; and methods for treating or preventing an metabolic disease comprising the administration of an effective amount of a fatty acid niacin conjugate.Type: GrantFiled: March 22, 2012Date of Patent: November 6, 2012Assignee: Catabasis Pharmaceuticals, Inc.Inventors: Jill C. Milne, Michael R. Jirousek, Jean E. Bemis, Chi B. Vu
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Publication number: 20120263775Abstract: The present invention relates to a method for producing granules comprising a pesticide, comprising the spraying-on of a pesticide-containing spray liquid in the region of a near-circular gas/material stream of a spouted-bed apparatus onto the particle surface of the material, and the drying and granulation in the gas stream. Furthermore, the invention relates to granules comprising a pesticide, obtainable by said method, where the granules have a roundness of at least 0.85.Type: ApplicationFiled: October 25, 2010Publication date: October 18, 2012Applicant: BASF SEInventors: Stefan Blei, Karl-Heinrich Schneider, Hans-Michael Fricke, Albert Werner
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Publication number: 20120264791Abstract: The invention relates to fatty acid niacin conjugates; compositions comprising an effective amount of a fatty acid niacin conjugate; and methods for treating or preventing an metabolic disease comprising the administration of an effective amount of a fatty acid niacin conjugate.Type: ApplicationFiled: April 19, 2012Publication date: October 18, 2012Applicant: CATABASIS PHARMACEUTICALS, INC.Inventors: Jill C. Milne, Michael R. Jirousek, Jean E. Bemis, Chi B. Vu, Amal Ting
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Publication number: 20120258989Abstract: The present invention relates to the use of succinate dehydrogenase Inhibitors for extending shelf life and storage stability of fruits and vegetables, to a method for extending shelf life of fruits and vegetables by applying a succinate dehydrogenase inhibitor to the crops prior to the harvest of the fruits or vegetables and to a fruit or vegetable treated with a succinate dehydrogenase Inhibitor.Type: ApplicationFiled: May 25, 2012Publication date: October 11, 2012Applicant: BAYER CROPSCIENCE AGInventors: Heiko RIECK, Hélène LACHAISE, Gilbert LABOURDETTE, Pete Howard DAVIES, Dominique STEIGER, Luk DE MAEYER, George Hauley MUSSON, IV, Lorianne FOUGHT, Sylvain TAFFOREAU
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Publication number: 20120252850Abstract: The invention relates to niacin conjugated fatty acid mixtures; compositions comprising an effective amount of a niacin conjugated fatty acid mixture; and methods for treating or preventing an metabolic disorder comprising the administration of an effective amount of a niacin conjugated fatty acid mixture.Type: ApplicationFiled: April 2, 2012Publication date: October 4, 2012Applicant: CATABASIS PHARMACEUTICALS, INC.Inventors: Jill C. Milne, Michael R. Jirousek, Jean E. Bemis, Chi B. Vu
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Publication number: 20120245137Abstract: Methods and compounds effective in ameliorating conditions characterized by unwanted calcium channel activity, particularly unwanted N-type and/or T-type calcium channel activity, are disclosed. Specifically, a series of compounds containing aryl sulphone derivatives, as exemplified by Formula (I).Type: ApplicationFiled: September 17, 2010Publication date: September 27, 2012Applicant: Zalicus Pharmaceuticals Ltd.Inventors: Hassan A. Pajouhesh, Robert Galemmo, JR., Richard Holland, Yuanxi Zhou, Yongbao Zhu, Eric Simonson, Navjot Chahal, Mike Grimwood
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Publication number: 20120245115Abstract: The present invention is directed to nicotinamide derivatives, and their use in treating lipoprotein abnormalities, alone or in combination with a statin.Type: ApplicationFiled: June 11, 2012Publication date: September 27, 2012Applicant: Cortria CorporationInventors: Robert BENDER, Stefan Chlopicki, Jerzy Gebicki
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Publication number: 20120245107Abstract: The invention relates to formulations of an antimicrobial agent, a lipid, and optionally a surfactant, and uses thereof for reducing the proliferation and viability of microbial agents.Type: ApplicationFiled: June 7, 2012Publication date: September 27, 2012Inventors: William Henry, Henk-Andre Kroon, Linda Summerton
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Patent number: 8273380Abstract: A beverage for minimizing or reducing jet lag symptoms preferably includes vitamin B3, vitamin B5, vitamin B6, vitamin B12, vitamin D, zinc, calcium, iodine, magnesium, manganese, ginseng, ginkgo biloba, grape seed extract, Echinacea extract and water. A method for minimizing or reducing jet lag symptoms including ingestion of the beverage by a traveler, one hour prior to a flight, and/or during the flight, and/or after a flight.Type: GrantFiled: May 19, 2009Date of Patent: September 25, 2012
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Publication number: 20120237446Abstract: The present invention relates to novel compounds (3-aminopropen-1-ones) useful for binding and imaging beta amyloid deposits and their use in detecting or treating Alzheimer's disease and amyloidosis.Type: ApplicationFiled: March 26, 2012Publication date: September 20, 2012Applicant: BAYER PHARMA AKTIENGESELLSCHAFTInventors: Ulrike Röhn, Hermann Künzer, Tobias Heinrich, Markus Berger, Damian Brockschnieder, Sabine Krause, Thomas Dyrks, Andrea Thiele, Ursula Mönning, Ulf Bömer
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Patent number: 8263527Abstract: Insecticidal compositions suitable for use in preparation of insecticidal liquid fertilizers comprising a pyrethroid, a hydrated aluminum-magnesium silicate, and at least one dispersant selected from the group consisting of a sucrose ester, a lignosulfonate, an alkylpolyglycoside, a naphthalenesulfonic acid formaldehyde condensate and a phosphate ester are disclosed.Type: GrantFiled: September 9, 2011Date of Patent: September 11, 2012Assignee: FMC CorporationInventor: Timothy Martin
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Patent number: RE43802Abstract: ?- and ?-amino acid hydroxyethylamino sulfonamide compounds are effective as retroviral protease inhibitors, and in particular as inhibitors of HIV protease.Type: GrantFiled: September 21, 2011Date of Patent: November 13, 2012Assignee: G.D. Searle LLCInventors: Michael L. Vazquez, Richard A. Mueller, John J. Talley, Daniel P. Getman, Gary A. DeCrescenzo, John N. Freskos, Deborah E. Bertenshaw, Robert M. Heintz