Zinc Patents (Class 514/494)
  • Patent number: 9993407
    Abstract: Described herein are methods of cleaning a tooth comprising administering a composition comprising a zinc amino acid halide complex to the oral cavity; and retaining the composition in the oral cavity for a time sufficient to form a precipitate.
    Type: Grant
    Filed: January 20, 2017
    Date of Patent: June 12, 2018
    Assignee: Colgate-Palmolive Company
    Inventors: Zhiqiang Liu, Long Pan, Shaotang Yuan, Jairajh Mattai, James G. Masters
  • Patent number: 9775799
    Abstract: Disclosed is a microneedle coating composition comprising a physiologically active substance (excluding Japanese encephalitis vaccine antigen), a basic amino acid, and an acid, wherein the mole number of the acid for one mole of the basic amino acid is larger than 1/(N+1) and less than 2, where N represents the valence of the acid.
    Type: Grant
    Filed: February 12, 2014
    Date of Patent: October 3, 2017
    Assignee: HISAMITSU PHARMACEUTICAL CO., INC.
    Inventors: Takuya Sugahara, Kazuya Machida
  • Patent number: 9655924
    Abstract: Disclosed herein are compositions for treatment of ear infection (such as bacterial and/or yeast infection) in human or veterinary subjects. In some embodiments the compositions include silver microparticles, for example about 0.1% silver microparticles, about 0.2% silver microparticles, or about 0.4% silver microparticles. Also disclosed are methods for treating ear infection in a subject utilizing one or more of the disclosed compositions, for example sequential application of compositions including about 0.1% silver microparticles, about 0.2% silver microparticles, and about 0.4% silver microparticles to the ear canal of the subject. In some examples, one or more of the disclosed compositions are provided in a kit.
    Type: Grant
    Filed: April 8, 2015
    Date of Patent: May 23, 2017
    Assignee: BioMedtrix, LLC
    Inventors: Christopher G. Sidebotham, Alan Mundell
  • Patent number: 9414599
    Abstract: A process is described for the preparation of a composition comprising a metal complex in an oily organic matrix, the latter being at the same time able to promote the formation of the complex. Said process also envisages that the complex, once formed, is not separated from said oily organic matrix, but the resulting composition is used as such, as having observed that the performances of the complex present therein is thus improved.
    Type: Grant
    Filed: June 7, 2012
    Date of Patent: August 16, 2016
    Assignee: Volare & Connecting, LLC
    Inventor: Giuliano Leonardi
  • Patent number: 9174935
    Abstract: The present invention is directed to a compound comprising a bis[thiohydrazide amide] or a deprotonated form thereof, complexed to a transition metal cation, wherein the bis[thiohydrazide amide] is represented by Structural Formula (I), or a prodrug, isomer, ester, salt, hydrate, solvate, polymorph or a deprotonated form thereof. In one embodiment, the compound is represented by Structural Formula (II), or a prodrug, isomer, ester, salt, hydrate, solvate or polymorph thereof. The present invention also provides a pharmaceutical composition comprising the compound of the invention and method of use thereof.
    Type: Grant
    Filed: October 21, 2009
    Date of Patent: November 3, 2015
    Assignee: Synta Pharmaceuticals Corp.
    Inventors: Masazumi Nagai, Jianhua Shen
  • Patent number: 9149042
    Abstract: The present invention relates to a stable antiseptic solution comprising: a di(4-chlorophenyldiguanido) compound or a pharmaceutically acceptable salt thereof, wherein said di(4-chlorophenyldiguanido) compound or a pharmaceutically acceptable salt thereof is a compound of formula (I) or a pharmaceutically acceptable salt thereof. The invention further relates to a process for preparing said antiseptic solution.
    Type: Grant
    Filed: March 14, 2012
    Date of Patent: October 6, 2015
    Assignee: Medichem, S.A.
    Inventors: Marina Puigvert Colomer, Sergio Lloret Perez
  • Patent number: 9051335
    Abstract: An antipruritic against pruritus caused by multiple sclerosis is disclosed.
    Type: Grant
    Filed: March 9, 2006
    Date of Patent: June 9, 2015
    Assignee: TORAY INDUSTRIES, INC.
    Inventors: Hideo Umeuchi, Koki Ueno, Hiroshi Miyakawa
  • Publication number: 20150148413
    Abstract: The present invention relates to methods kits and combined compositions using DFO-metal complexes, specifically, Zinc-desferrioxamine (Zn-DFO), gallium-desferrioxamine (Ga-DFO) complexes and any combinations thereof for preventing, treating, ameliorating or inhibiting an immune-related disorder, specifically, a skin-related inflammatory disorder such as psoriasis, an inflammatory respiratory condition such as asthma, and an autoimmune disease such as diabetes and any immune-related disorder.
    Type: Application
    Filed: January 27, 2015
    Publication date: May 28, 2015
    Inventors: Mordechai Chevion, Vladimir Vinokur, Eduard Berenshtein, Ron Eliashar, Baruch Bulvik
  • Publication number: 20150141504
    Abstract: The invention relates to the field of medicine, and specifically to preparations for treating skin lesions, in particular viral, benign, precancerous and cancerous, non-metastasizing, dysplastic and inflammatory lesions of the visible mucous membranes, and also viral and fungal skin and nail lesions, and for correcting wrinkles and senile pigment blemishes, said preparations comprising solutions of complex compounds of salts of zinc and alpha-chlorocarboxylic acids of general formula [Zn(RCH2?xClxCOOH) (H2O)4?n]+2 .2[RCH2?x ClxCOO]?, where R=alkyl, H or Cl, x=1-2 and n=0-4, in a corresponding alpha-chlorocarboxylic acid, wherein the content of zinc in the solution is 0.25-10.0% and the content of acid is 10-90%. The preparation may additionally contain an additive perfume, for example an ethyl ester of the corresponding alpha-chlorocarboxylic acid. The treatment method consists in that 2-5 doses of the preparation, which has been precooled to 10-15° C.
    Type: Application
    Filed: November 14, 2011
    Publication date: May 21, 2015
    Applicant: OBSCHESTVO S OGRANITCHENNOI OTVETSTVENNOSTJU "OXYGON"
    Inventors: Shalva Iosifovitch Mardi, Lev Aleksandrovich Ustynyuk
  • Patent number: 9034393
    Abstract: Bioactive agrichemical concentrates and compositions having improved bioactivity comprising combinations of acid solutions and conventional bioactive agrichemical actives or formulations.
    Type: Grant
    Filed: September 14, 2012
    Date of Patent: May 19, 2015
    Assignee: SCIESSENT LLC
    Inventor: Joseph J. Crudden
  • Publication number: 20150105461
    Abstract: The present invention relates to metal complexes, processes for their preparation and their use as pharmaceutical or veterinary agents, in particular for the treatment of conditions in which metal delivery can prevent, alleviate or ameliorate the condition. There are a number of clinical conditions which are caused by or associated with abnormal levels of metals (typically low metal levels). Conditions in of this type include cancer and conditions characterised by or associated with oxidative damage, more specifically neurodegenerative conditions such as Alzheimer's disease, Parkinson's disease or Huntington's disease. The invention also relates to ligands useful in the preparation of metal complexes of this type.
    Type: Application
    Filed: December 16, 2014
    Publication date: April 16, 2015
    Applicant: The University of Melbourne
    Inventors: Kevin J. Barnham, Paul S. Donnelly, Anthony R. White
  • Publication number: 20150099635
    Abstract: An agricultural oil-based suspension formulation comprising an active ingredient suspended in finely divided form in an oil and at least one unsaturated rubber-type copolymer or a mixture thereof, wherein the rubber-type copolymer comprises at least styrene as a residue.
    Type: Application
    Filed: June 8, 2012
    Publication date: April 9, 2015
    Inventors: Andrew David Holliday, Dilek Saylik, Rowan Brown, Karen Vab Der Sande, Andrew F. Kirby, Robert E. Bohun
  • Patent number: 8986741
    Abstract: A sunscreen composition for application for plants comprises Titanium Dioxide (TiO2), Zinc Oxide (ZnO), Silicon Dioxide (SiO2), a surfactant, wetting agent, dispersant (SWD) and water. The composition forms a suspension concentrate when combined that when diluted in water provides a solution that provides uniform coverage using convention spraying equipment. A method of protecting plants including turfgrass from ultraviolet radiation, heat stress and/or sunburn comprises combining TiO2, ZnO, SiO2, SWD and water to form a suspension concentrate. The suspension concentrate is then diluted in water and applied to an area in which sun protection is desired.
    Type: Grant
    Filed: October 15, 2013
    Date of Patent: March 24, 2015
    Inventor: Scott May
  • Patent number: 8987244
    Abstract: Methods are provided for reducing copper values for, by way of example, treating, preventing or ameliorating tissue damage such as, for example, tissue damage that may be caused by (i) disorders of the heart muscle (for example, cardiomyopathy or myocarditis) such as idiopathic cardiomyopathy, metabolic cardiomyopathy which includes diabetic cardiomyopathy, alcoholic cardiomyopathy, drug-induced cardiomyopathy, ischemic cardiomyopathy, and hypertensive cardiomyopathy, (ii) atheromatous disorders of the major blood vessels (macrovascular disease) such as the aorta, the coronary arteries, the carotid arteries, the cerebrovascular arteries, the renal arteries, the iliac arteries, the femoral arteries, and the popliteal arteries, (iii) drug induced, and metabolic (including hypertensive and/or diabetic disorders of small blood vessels (microvascular disease) such as the retinal arterioles, the glomerular arterioles, the vasa nervorum, cardiac arterioles, and associated capillary beds of the eye, the kidney, the h
    Type: Grant
    Filed: September 18, 2013
    Date of Patent: March 24, 2015
    Assignee: PhilERA New Zealand Limited
    Inventors: Garth J. S. Cooper, John R. Baker
  • Patent number: 8975294
    Abstract: The present invention relates to methods kits and combined compositions using DFO-metal complexes, specifically, Zinc-desferrioxamine (Zn-DFO), gallium-desferrioxamine (Ga-DFO) complexes and any combinations thereof for preventing, treating, ameliorating or inhibiting an immune-related disorder, specifically, a skin-related inflammatory disorder such as psoriasis, an inflammatory respiratory condition such as asthma, and an autoimmune disease such as diabetes and any immune-related disorder.
    Type: Grant
    Filed: August 19, 2010
    Date of Patent: March 10, 2015
    Assignees: Hadasit Medical Research Services and Development Ltd., Yissum Research Development Company of the Hebrew University of Jerusalem Ltd.
    Inventors: Mordechai Chevion, Vladimir Vinokur, Eduard Berenshtein, Ron Eliashar, Baruch Bulvik
  • Patent number: 8975295
    Abstract: Methods of altering properties of tissues, by providing an effective modifying amount of zinc, which may be in the form of zinc ions. This is accomplished through the use of topical compositions containing one or more zinc-containing components such as salts and/or other zinc compounds or complexes, particularly zinc acetate. Altering properties of tissues includes increasing or decreasing fatty tissue, increasing or decreasing epidermal thickness, increasing elastin content, and preventing or treating gum regression or atrophy. Also disclosed is the provision of a contact lens coated with a zinc-containing material, to improve vision by increasing elastin content of the lens of the eye through release of zinc ions.
    Type: Grant
    Filed: October 22, 2003
    Date of Patent: March 10, 2015
    Assignee: Precision Dermatology, Inc.
    Inventor: Jacob M. Waugh
  • Patent number: 8968791
    Abstract: The present invention provides a dietary supplement that promote the growth, repair, and maintenance of mammalian bone and joint connective tissue. In particular, the dietary supplement comprises a combination of at least one metal chelate and at least one chondroprotective agent.
    Type: Grant
    Filed: May 30, 2008
    Date of Patent: March 3, 2015
    Assignee: Novus International, Inc.
    Inventors: Jeremy D. Moore, Thomas R. Hampton, Robert Harrell
  • Publication number: 20150057345
    Abstract: Method for improving the feed efficiency in poultry husbandry wherein poultry is provided with a compound directly upon hatching, the compound being selected from a lactylate in accordance with formula 1, or a Na, K, Ca, Mg, Fe(II), Zn, NH4, or Cu(II) salt thereof, R2-COO—[—CH(CH3)-COO]n-R1??Formula 1 a glycolylate of formula 2, or a Na, K, Ca, Mg, Fe(II), Zn, NH4, or Cu(II) salt thereof. R2-COO—[—CH2-COO]n-R1??Formula 2: a lactate ester of formula 3, HO—CH(CH3)-COO—R2??Formula 3: and/or a glycolic acid ester of formula 4, HO—CH2-COO—R2??Formula 4: In the above formulas R1 is selected from H, n stands for an integer with value of 1-10, and R2 stands for C1-C35 alkyl or alkenyl chain, which may be branched or unbranched. The effective compound provided to poultry is dosed level in a first part of their life-span higher than the dose level in other part of their life span.
    Type: Application
    Filed: April 3, 2013
    Publication date: February 26, 2015
    Applicant: PURAC BIOCHEM BV
    Inventors: Bart Jan Boomsma, Anne Cazemier
  • Patent number: 8952057
    Abstract: Compositions containing polymetal complexes are useful in treating anorectal disorders.
    Type: Grant
    Filed: June 16, 2011
    Date of Patent: February 10, 2015
    Assignee: JR Chem, LLC
    Inventor: José E. Ramirez
  • Publication number: 20150038577
    Abstract: A nutritional supplement for a human, the supplement having a chelate comprised of an N-acetyl-L-cysteine ligand bonded to a metal to form a chelate ring. A method for preparing a chelate comprised of N-acetyl-L-cysteine ligand and a metal having the steps of: dissolving an amount of N-acetyl-L-cysteine in an aqueous solution, adding a metal to the aqueous solution, stifling and heating the aqueous solution, and removing the solvent under reduced pressure. A method of treating a human for one or more of oxidative stress, cardiovascular disease, cerebrovascular disease, neurodegenerative diseases, Alzheimer's disease, ADHD, bipolar, schizophrenia, autism, dementia, and HIV in a human comprising administering an effective amount of a composition having N-acetyl-L-cysteine in a chelate formation with a metal. A compound having a chelate formulation with a metal being chelated by an N-acetyl-L-cysteine ligand.
    Type: Application
    Filed: December 27, 2013
    Publication date: February 5, 2015
    Inventors: Xueju Xie, Rhett Sean Daniels, Patricia Gahan
  • Publication number: 20140364491
    Abstract: An orally deliverable dosage system comprises (a) iron in a form of one or more physiologically acceptable iron grades, compounds and/or complexes; and (b) an agent to mitigate one or more gastrointestinal adverse effects of unabsorbed iron, said agent comprising one or both of a zinc component and a chelator component, said zinc component if present comprising one or more physiologically acceptable zinc compounds and/or complexes, and said chelator component if present comprising an ion-chelating compound formulated for release distal to the primary site of iron absorption in the duodenum.
    Type: Application
    Filed: May 28, 2014
    Publication date: December 11, 2014
    Applicant: AMIP, LLC
    Inventor: Jonathan David Bortz
  • Publication number: 20140350099
    Abstract: Compounds for use in the treatment or prophylaxis of pain, including acute and chronic pain (e.g., nociceptive pain, neuropathic pain, headaches, migraine), represented by general formula I: in which: the dotted line represents a single or a double bond; and R5 and R5? are independently —H, —OH or —OR6, where R6 is a linear or branched C1-C4 alkyl; X is —CH2O—; Z is —CH2CH2O—, —CH(CH3)CH2O— or —CH2CH(CH3)O—; m is 1; and n is an integer of 1-5. The compounds of the invention are also effective for reducing inflammation and may be used alone or in combination with other analgesics.
    Type: Application
    Filed: July 21, 2014
    Publication date: November 27, 2014
    Inventor: Eliahu Kaplan
  • Patent number: 8894978
    Abstract: A new skin care system includes day and night skin cream compositions comprising nutrients and antioxidants for use by children between six months and eighteen years of age. The day skin cream composition provides protection from UV radiation and the night skin cream composition contains no sun protection ingredients and elevated levels of nutrients and antioxidants. A child-friendly bottle for each composition can be used by young children without difficulty. A fragrance included in each composition is popular with children, and the bottle for the day composition has graphics indicating day-time use and the bottle for the night composition has graphics indicating night-time use. The day composition is applied topically each day to the face after tooth-brushing, and the night composition is applied topically to the face each night after tooth-brushing.
    Type: Grant
    Filed: April 25, 2014
    Date of Patent: November 25, 2014
    Inventor: William Scott Prendergast
  • Publication number: 20140343140
    Abstract: [Problem] To provide an agent for preventing and/or treating veisalgia. [Solution] Provided is an agent for preventing and/or treating veisalgia, the agent including an ALA (5-aminolevulinic acid).
    Type: Application
    Filed: November 30, 2012
    Publication date: November 20, 2014
    Inventors: Tohru Tanaka, Motowo Nakajima, Fuminori Abe, Satofumi Kawata
  • Patent number: 8889038
    Abstract: This invention relates to wood preservatives containing copper complexes and calcium ions, zinc ions or calcium and zinc ions for protection of wood, cellulose, hemicellulose, lignocellulose, cellulosic materials and articles derived from cellulosic materials from decay caused by fungi. The calcium ions, zinc ions, or calcium and zinc ions improve the penetration of copper preservative agent into the interior of a treated material or article.
    Type: Grant
    Filed: December 18, 2008
    Date of Patent: November 18, 2014
    Assignee: E I du Pont de Nemours and Company
    Inventors: Albert Gordon Anderson, Mark A. Scialdone
  • Patent number: 8865687
    Abstract: The present invention relates to a preparation suitable for the prevention and/or treatment of vascular disorders, comprising the following fractions: fraction a) consisting of long chain polyunsaturated fatty acids; fraction b) consisting of phospholipids, which fraction contains at least two different phospholipids selected from the group consisting of phosphatidylserine, phosphatidylinositol, phosphatidylcholine and phosphatidylethanolamine. fraction c) consisting of compounds which are a factor in methionine metabolism, which fraction contains at least one member selected from the group consisting of folic acid, vitamin B12, vitamin B6, magnesium and zinc.
    Type: Grant
    Filed: February 14, 2013
    Date of Patent: October 21, 2014
    Assignee: N.V. Nutricia
    Inventors: Amanda Johanne Kiliaan, Robert Johan Joseph Hageman
  • Patent number: 8858922
    Abstract: Disclosed is a new composition of matter that is a compound which also is presented as a dispersion with broad UVA and UVB spectral absorption stability, heat absorption, and insulation properties, anti-microbial, water resistance, and high SPF properties. The composition of matter is a zinc oxide complex that is provided with distilled water buffered to a pH of greater than 10 using ammonium hydroxide, L-arginine, or other buffering agents, and zinc oxide particles. The zinc oxide complex may be dried and rinsed to increase stability. An emollient, such as glycerine, and/or an emulsifier such as a combination of cetearyl alcohol and cetearyl glucoside and/or sodium stearoyl glutamate and/or cetearyl glucoside may also be added to the zinc oxide complex. The zinc oxide complex is made from natural-based, earth-derived, Ecocert® certified ingredients is non-toxic, and may be used or combined with any compound in which UVA/UVB stability is desired.
    Type: Grant
    Filed: November 22, 2010
    Date of Patent: October 14, 2014
    Assignee: 3rd Rock Sunblock, Inc.
    Inventor: Guerry L. Grune
  • Publication number: 20140303081
    Abstract: Nanoparticles include a core and one or more targeting moieties, as well as one or more contrast agents or one or more therapeutic agents. The contrast agents or therapeutic agents may be contained or embedded within the core. If the nanoparticle includes therapeutic agents, the agents are preferably released from the core at a desired rate. The core may be biodegradable and may release the agents as the core is degraded or eroded. The targeting moieties preferably extend outwardly from the core so that they are available for interaction with cellular components, which interactions will target the nanoparticles to the appropriate cells, such as apoptotic cells; organelles, such as mitochondria; or the like. The targeting moieties may be tethered to the core or components that interact with the core.
    Type: Application
    Filed: August 31, 2012
    Publication date: October 9, 2014
    Applicant: UNIVERSITY OF GEORGIA FOUNDATION, INC.
    Inventors: Shanta Dhar, Sean Marrache
  • Patent number: 8853265
    Abstract: An oral spray composition for preventing and/or reducing the symptoms of the common cold including a zinc formulation containing both zinc acetate and zinc gluconate to ensure sustained availability of increased amounts of ionizable zinc.
    Type: Grant
    Filed: July 13, 2010
    Date of Patent: October 7, 2014
    Assignee: Zicam, LLC
    Inventor: Tim Clarot
  • Publication number: 20140271760
    Abstract: Described are antimicrobial liquid products comprising one or more antimicrobial organometallic additives dispersed throughout an organic host liquid.
    Type: Application
    Filed: May 14, 2014
    Publication date: September 18, 2014
    Applicant: DMR INTERNATIONAL, INC.
    Inventors: MARC CHASON, DANIEL ROMAN GAMOTA, RICK LATELLA
  • Publication number: 20140248221
    Abstract: Compositions containing polymetal complexes useful in treating disorders of the oral mucosa, lips, and perioral regions are described.
    Type: Application
    Filed: May 13, 2014
    Publication date: September 4, 2014
    Applicant: JR CHEM, LLC
    Inventor: Jose E. Ramirez
  • Patent number: 8822532
    Abstract: Certain bis[thio-hydrazide amide]-related compounds are found to be surprisingly effective at treating with leukemia, e.g., acute myeloid leukemia (AML). Methods of treating a subject with AML including administering bis[thio-hydrazide amide]-related compounds described herein, are disclosed.
    Type: Grant
    Filed: December 6, 2010
    Date of Patent: September 2, 2014
    Assignee: Synta Pharmaceuticals Corp.
    Inventors: Masazumi Nagai, Jianhua Shen
  • Publication number: 20140242404
    Abstract: The present invention relates to a wood preservative formulation comprising a biocidal agent which is a copper or zinc ion complexed with an amino compound selected from the group consisting of ammonia, a water soluble amine or alkanolamine and an aminocarboxylic acid and a stabilizer, as well as to aqueous treatment solutions comprising such a formulation and methods of treating wood or other cellulosic material utilising said formulation.
    Type: Application
    Filed: May 2, 2014
    Publication date: August 28, 2014
    Applicant: ARCH TIMBER PROTECTION LIMITED
    Inventors: Kevin HUGHES, Craig Andrew MARS, Andrew HUGHES
  • Publication number: 20140242137
    Abstract: Compositions and methods for use in treating, in particular, lignocellulosic substrates such as lumber, are provided; wherein said compositions comprise a preservative or biocidal species, other than boron, in the form of a glycolate. The methods may be used for the purpose of, for example, preventing the growth of pest organisms, or for providing other specific properties to the substrate.
    Type: Application
    Filed: July 27, 2012
    Publication date: August 28, 2014
    Applicant: Matterworks One Limited
    Inventor: Nigel Paul Maynard
  • Patent number: 8815948
    Abstract: An alternative method of delivery of homeopathic medicines by targeting delivery to the MALT's, especially of the intestinal tract and in high volumes.
    Type: Grant
    Filed: February 10, 2005
    Date of Patent: August 26, 2014
    Inventors: Char Tara Albert, Floyd E. Taub
  • Publication number: 20140234394
    Abstract: An enhanced article which has a beneficial contact surface intended to allow bioabsorption of beneficial materials through the user's contact with the enhanced article in use. A functional or ornamental article which has at least one contact surface intended to come in contact with a human user includes a beneficial contact surface for covering the article's contact surface and providing a beneficial surface contact compound adapted to come in contact with a human user touching the article. The beneficial contact surface is connected to the article so that the contact surface of the article is covered by the beneficial contact surface. The presence of the beneficial surface contact compound in the beneficial contact surface means results in the exposure of the user's skin to the beneficial surface contact compound to allow absorption by the user.
    Type: Application
    Filed: February 19, 2013
    Publication date: August 21, 2014
    Inventors: William A. McDonough, Aly Khalifa
  • Publication number: 20140228744
    Abstract: Appliances for oral use including compositions containing polymetal complexes useful in treating disorders of the oral mucosa, lips, and perioral region are described.
    Type: Application
    Filed: April 16, 2014
    Publication date: August 14, 2014
    Applicant: JR CHEM, LLC
    Inventor: Jose E. Ramirez
  • Patent number: 8802120
    Abstract: Bioactive agrichemical concentrates and compositions having improved bioactivity comprising combinations of acid solutions and conventional bioactive agrichemical actives or formulations.
    Type: Grant
    Filed: September 14, 2012
    Date of Patent: August 12, 2014
    Assignee: Sciessent LLC
    Inventor: Joseph J. Crudden
  • Publication number: 20140205644
    Abstract: The present invention concerns antimicrobial expandable polystyrene (EPS) beads, comprising as main antimicrobial agent metal ions selected from silver and copper and combinations thereof, which antimicrobial agent(s) may be either mixed into the polymer matrix or coated onto the beads. The invention also concerns a method for producing the coated form of these antimicrobial beads.
    Type: Application
    Filed: August 29, 2012
    Publication date: July 24, 2014
    Applicant: StyroChem Finland Oy
    Inventors: Jyri Nieminen, Ville Nurminen, Markus Mäki
  • Publication number: 20140205639
    Abstract: The present invention relates to pharmaceutical compositions suitable for the topical treatment of fungal infections of the skin and nails, such as tinea pedia and tinea cruris, among others. The active ingredients of the present compositions are low molecular weight organic acids and their salts, many of which are previously known as antifungal agents to some degree but which, when used in combination, produce a synergistic enhancement in antifungal potency such that the combined effect is greater than that when used by the agents alone. The antifungal activity of the active ingredients is further enhanced through the use of non-volatile hygroscopic solvents rather than the aqueous or volatile organic solvents used in the art.
    Type: Application
    Filed: January 22, 2013
    Publication date: July 24, 2014
    Applicant: bioCEPTA Corporation
    Inventor: Peter Mladenovich
  • Publication number: 20140199358
    Abstract: Described are antimicrobial polymer products made from mixtures of antimicrobial organometallic additives dispersed throughout a polymer host matrix.
    Type: Application
    Filed: March 15, 2013
    Publication date: July 17, 2014
    Applicant: DMR INTERNATIONAL, INC.
    Inventors: MARC CHASON, Daniel Roman Gamota, Rick Latella
  • Publication number: 20140199359
    Abstract: Described are antimicrobial polymer products made from mixtures of antimicrobial organometallic additives dispersed throughout a polymer host matrix.
    Type: Application
    Filed: March 15, 2013
    Publication date: July 17, 2014
    Applicant: DMR INTERNATIONAL, INC.
    Inventors: MARC CHASON, DANIEL ROMAN GAMOTA, RICK LATELLA
  • Publication number: 20140199356
    Abstract: Described are antimicrobial polymer products made from mixtures of antimicrobial organometallic additives dispersed throughout a polymer host matrix.
    Type: Application
    Filed: March 15, 2013
    Publication date: July 17, 2014
    Inventors: MARC CHASON, Daniel Roman Gamota, Rick Latella
  • Patent number: 8778410
    Abstract: The present invention provides an oral or enteral composition incorporating not only BCAA but other nutrients to be conducive to comprehensive recovery from fatigue, and improvement in total physical condition. The oral or enteral composition is formulated as a composite of a branched-chain amino acid, coenzyme Q10, L-carnitine, a citric acid, and zinc.
    Type: Grant
    Filed: February 19, 2009
    Date of Patent: July 15, 2014
    Assignees: Earnest Medicine Co., Ltd., Otsuka Pharmaceutical Factory, Inc.
    Inventors: Takashi Higashiguchi, Takako Hatakeyama
  • Patent number: 8778406
    Abstract: A composition and method which prevents or mitigates irritation on the skin of a subject by protecting against or relieving chafing, itching and moisture, and which provides a cooling sensation where applied.
    Type: Grant
    Filed: August 9, 2011
    Date of Patent: July 15, 2014
    Assignee: Joyce Labs, LLC
    Inventors: Timothy C. Joyce, James Hammer
  • Publication number: 20140193495
    Abstract: The present invention relates to controlled release pharmaceutical compositions comprising fumaric acid ester(s) as active substance(s). The compositions are suitable for use in the treatment of e.g. psoriasis or other hyperproliferative, inflammatory or autoimmune disorders and are designated to release the fumaric acid ester in a controlled manner so that local high concentrations of the active substance within the gastrointestinal tract upon oral administration can be avoided and, thereby, enabling a reduction in gastro-intestinal related side-effects.
    Type: Application
    Filed: March 13, 2014
    Publication date: July 10, 2014
    Applicant: FORWARD PHARMA A/S
    Inventors: Henrik NILSSON, Florian SCHOENHARTING, Bernd W. MUELLER, Joseph R. ROBINSON
  • Patent number: 8759385
    Abstract: Hair treatment composition comprising an azole fungicide and zinc gluconate and wherein the composition does not comprise Trichogen®.
    Type: Grant
    Filed: April 13, 2010
    Date of Patent: June 24, 2014
    Assignee: Conopco Inc.
    Inventors: Jason Shaun Burry, Richard Livesey Evans, Graham Andrew Turner
  • Publication number: 20140171501
    Abstract: The invention relates to the field of medicine, and specifically to preparations for treating skin lesions, in particular viral, benign, precancerous and cancerous, non-metastasizing, dysplastic and inflammatory lesions of the visible mucous membranes, and also viral and fungal skin and nail lesions, and for correcting wrinkles and senile pigment blemishes, said preparations comprising solutions of complex compounds of salts of zinc and alpha-chlorocarboxylic acids of general formula [Zn(RCH2?xClxCOOH) (H2O)4?n]+2 .2[RCH2?x ClxCOO]?, where R=alkyl, H or Cl, x=1-2 and n=0-4, in a corresponding alpha-chlorocarboxylic acid, wherein the content of zinc in the solution is 0.25-10.0% and the content of acid is 10-90%. The preparation may additionally contain an additive perfume, for example an ethyl ester of the corresponding alpha-chlorocarboxylic acid. The treatment method consists in that 2-5 doses of the preparation, which has been precooled to 10-15° C.
    Type: Application
    Filed: November 14, 2011
    Publication date: June 19, 2014
    Applicant: OBSCHESTVO S OGRANITCHENNOI OTVETSTVENNOSTJU "OXYGON"
    Inventors: Shalva Iosifovitch Mardi, Lev Aleksandrovich Ustynyuk
  • Patent number: 8747817
    Abstract: A new skin care system includes day and night skin cream compositions comprising nutrients and antioxidants for use by children between six months and eighteen years of age. The day skin cream composition provides protection from UV radiation and the night skin cream composition contains no sun protection ingredients and elevated levels of nutrients and antioxidants. A child-friendly bottle for each composition can be used by young children without difficulty. A fragrance included in each composition is popular with children, and the bottle for the day composition has graphics indicating day-time use and the bottle for the night composition has graphics indicating night-time use. The day composition is applied topically each day to the face after tooth-brushing, and the night composition is applied topically to the face each night after tooth-brushing.
    Type: Grant
    Filed: December 2, 2011
    Date of Patent: June 10, 2014
    Inventor: William Scott Prendergast
  • Patent number: RE45435
    Abstract: The addition of low concentrations of combinations of water-soluble organic salts of zinc to gels, creams, lotions or ointments can increase the ability of these products to reduce or prevent exogenous irritants from causing irritation of the underlying substrate. The addition of low concentrations of combinations of water-soluble organic zinc salts to these gels, creams, lotions or ointments also can reduce the irritation of skin or mucous membranes caused by the addition of potentially-irritating substances such as spermicides, microbicides, fungicides or other therapeutic agents to the gel, cream, lotion or ointment. The advantages of this anti-irritant approach over others, which generally employ high concentrations of single zinc salts, are the reduced potential for zinc toxicity, the reduced potential for toxicity related to zinc itself, and the preservation of the desirable biological properties of potentially-irritating therapeutic substances added to the gel, cream, lotion or ointment.
    Type: Grant
    Filed: November 9, 2012
    Date of Patent: March 24, 2015
    Assignee: The Trustees of Columbia University in the City of New York
    Inventors: Shanta M. Modak, Milind S. Shintre, Lauserpina Caraos, Trupti Gaonkar