R Contains Benzene Ring Patents (Class 514/615)
  • Patent number: 4968679
    Abstract: New 8-substituted 2-aminotetralins can be prepared from the corresponding aminotetralins or tetralones. They can be used in medicaments.
    Type: Grant
    Filed: May 22, 1989
    Date of Patent: November 6, 1990
    Assignee: Bayer Aktiengesellschaft
    Inventors: Bodo Junge, Bernd Richter, Thomas Glaser, Jorg Traber, George S. Allen
  • Patent number: 4863967
    Abstract: A compound having the structural formula ##STR1## wherein R.sup.1 and R.sup.2 are the same or different and are hydrogen, C.sub.1 -C.sub.6 alkyl, halogen or C.sub.1 -C.sub.4 alkoxy is disclosed. These compounds demonstrate utility as hypolipidemic agents.The present invention is also directed to a process for controlling lipidemia in mammals comprising treating mammals with a lipidemia controlling effective amount of the above-defined compound.Yet another aspect of the present invention is embodied in a pharmaceutical composition comprising the above compound and a pharmaceutically acceptable carrier therefor.
    Type: Grant
    Filed: June 16, 1986
    Date of Patent: September 5, 1989
    Assignee: Research Corporation
    Inventors: Iris H. Hall, Steven D. Wyrick
  • Patent number: 4814349
    Abstract: The present invention relates to methods for controlling insect populations and for protecting living plants from insect attack by applying to said plants or to the soil in which they are growin an insecticidally-effective amount of a substituted benzoic acid 1 or 2-alkyl or 2-cycloalkylhydrazide.Novel substituted benzoic acid 1 and 2-alkyl and 2-cycloalkylhydrazides effective as insecticides or intermediates for the preparation of insecticidal diacylhydrazides also are presented.
    Type: Grant
    Filed: November 12, 1986
    Date of Patent: March 21, 1989
    Assignee: American Cyanamid Company
    Inventors: Roger W. Addor, David G. Kuhn, Donald P. Wright, Jr.
  • Patent number: 4743614
    Abstract: Novel compounds of the following formula have restorative pharmacological activities in immuno-deficient hosts, ##STR1## wherein R.sup.1 is amino or a protected amino group,R.sup.2 is hydrogen, carboxy or a protected carboxy group,R.sup.3 is hydrogen, carboxy or a protected carboxy group,R.sup.4 is lower alkyl, amino(lower)alkyl, protected amino(lower)alkyl, carbamoyl(lower)alkyl or protected carbamoyl(lower)alkyl,R.sup.5 is hydrogen or lower alkyl, andR.sup.6 is hydrogen, hydroxyphenyl(lower)alkyl, imidazolyl(lower)alkyl or indolyl(lower)alkyl.
    Type: Grant
    Filed: March 4, 1986
    Date of Patent: May 10, 1988
    Assignee: Fujisawa Pharmaceutical Co., Ltd.
    Inventors: Hiroshi Terano, Yasuhisa Tsurumi, Hiroyuki Setoi, Masashi Hashimoto, Masanobu Kohsaka
  • Patent number: 4659714
    Abstract: Improved methods of anesthesia for mammals, especially humans, are provided wherein the prolonging effect upon local anesthesia which is exhibited by co-administration of vasoconstrictors, especially vasoconstrictors believed to act upon alpha adrenoreceptor sites on blood vessel walls, are provided. In accordance with a preferred embodiment, alpha adrenoreceptor blocking agents are aministered subsequent to the performance of surgery or dentistry under local anesthesia accomplished through co-administration of anesthesia and vasoconstrictor to cause reduction of prolonged anesthetic effect. Seriatim procedures are facilitated under local anesthesia through employment of the present invention. Improved patient aesthetics, diminution of self-inflicted trauma, and increased sensory feedback from patients are among the benefits conferred by the present invention.
    Type: Grant
    Filed: March 27, 1984
    Date of Patent: April 21, 1987
    Assignee: Dentsply, Ltd.
    Inventor: Stephen R. Watt-Smith
  • Patent number: 4600582
    Abstract: A method of reducing local adverse reactions which occur at the site of administration of parenterally administrable physiologically active compositions, to patients which comprises, prior to administration thereof, incorporating in said physiologically active compositions, a small but effective amount of a compound of the formulae, ##STR1## wherein n is an integer of from 1 to 6; R.sup.1 is H or lower alkyl; x is 0 or 1; each Y is H; and R is H, lower alkyl or acyl; and the non-toxic pharmaceutically acceptable salts thereof.
    Type: Grant
    Filed: September 7, 1982
    Date of Patent: July 15, 1986
    Assignee: Tetra Consultants, Inc.
    Inventors: Erik Stevens, Ernestina M. Van Hoeyveld
  • Patent number: 4600583
    Abstract: The method of improving the storage stability of parenterally administerable physiologically active compositions which comprises, incorporating in said compositions a small but effective amount of a compound of the formulae, ##STR1## wherein R is H, lower alkyl or acyl; each R.sup.1 is H or lower alkyl; and n is an integer of from 1 to 6; x is 0 or 1; each Y is H; and the non-toxic pharmaceutically acceptable salts thereof.
    Type: Grant
    Filed: September 7, 1982
    Date of Patent: July 15, 1986
    Assignee: Tetra Consultants Inc.
    Inventors: Erik Stevens, Ernestina M. Van Hoeyveld
  • Patent number: 4547524
    Abstract: Compounds of the formula ##STR1## wherein R.sub.1, R.sub.2, R.sub.3 and R.sub.4 are as herein defined useful as insecticides, is described.
    Type: Grant
    Filed: February 14, 1983
    Date of Patent: October 15, 1985
    Assignee: Hokko Chemical Industry Co., Ltd.
    Inventors: Kimiyoshi Kaneko, Hiromichi Ishikawa, Satoru Moriyama, Tsugio Uchiyama