Plural Alicyclic Rings Patents (Class 514/691)
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Publication number: 20110217389Abstract: Methods of treating, reducing, and/or preventing heat stress are provided. For example, provided is a method of treating or preventing heat stress in a subject comprising selecting a subject in need of heat stress treatment or prevention and administering an effective amount of one or more of astaxanthin and milk casein hydrolysate, or a derivative thereof to the subject. Also provided are methods of reducing the effects of a fever in a subject comprising administering an effective amount of one or more of astaxanthin, chromium and milk casein hydrolysate, or a derivative thereof, to the subject. Also provided are pharmaceutical compositions, comprising astaxanthin and one or more of chromium or milk casein hydrolysate.Type: ApplicationFiled: April 8, 2010Publication date: September 8, 2011Applicant: GEORGETOWN UNIVERSITYInventor: Harry George Preuss
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Publication number: 20110213002Abstract: The present invention relates generally to chemical agents useful in the treatment and prophylaxis of inflammatory conditions or in the amelioration of symptoms resulting from or facilitated by an inflammatory condition in a mammalian animal including human and primate, non-mammalian animal and avian species. More particularly, the present invention provides a chemical agent of the macrocyclic diterpene family obtaining from a member of the Euphorbiaceae family of plants or botanical or horticultural relatives thereof or derivatives or chemical analogues or chemically synthetic forms of the agents for use in the treatment or prophylaxis of an inflammatory condition or in the amelioration of symptoms resulting from or facilitated by an inflammatory condition in a mammal, animal or avian species.Type: ApplicationFiled: February 24, 2011Publication date: September 1, 2011Applicant: Peplin Research Pty Ltd.Inventors: James Harrison Aylward, Peter Gordon Parsons, Andreas Suhrbier, Kathleen Anne Turner
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Publication number: 20110178181Abstract: A personal care composition comprising a methyl naphthalenyl ketone or a derivative thereof, such as 1-(1,2,3,4,5,6,7,8-octahydro-2,3,8,8-tetramethyl-2naphthalenyl)-ethan-1-one, for down regulating at least one TRP receptor associated with a pain response, including but not limited to TRPV1 and TRPA1 receptors to reduce skin irritation associated with hair removal.Type: ApplicationFiled: January 10, 2011Publication date: July 21, 2011Inventors: Katharine Anne Bakes, Timothy Woodrow Coffindaffer, John Christian Haught, Helen Rochelle Kemp, Yakang Lin, Kotikanyadanam Tatachar Sreekrishna
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Patent number: 7976876Abstract: The present invention relates to an anti-bacterial, anti-virus, and anti-fungus composition, its preparation and use. The composition of the present invention mainly includes the following three ingredients in an adequate ratio: (A) a metal compound having a catalytic function; (B) a mixture of a coenzyme having reducing ability and a quinone, and (C) an additive. The anti-bacterial, anti-virus, and anti-fungus composition of the present invention is capable of destroying viruses as well as killing bacterial and fungi. Therefore, the composition can be formulated as an aerosol and a film for applying to protection devices such as respirators, masks, gloves, filters, condoms, etc. The present composition can also be used in household, vehicle, hospital, school, restaurant, hotel, internet coffee shop for applying to filter of air-conditioner, tap, stool, interior of elevator and its keyboard.Type: GrantFiled: September 29, 2008Date of Patent: July 12, 2011Assignee: Well-Being Biochemical Corp.Inventors: Jih-ru Hwu, Shwu-chen Tsay
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Publication number: 20110158921Abstract: The present invention provides methods of treating humans and animals with terpenes and terpenoids in order to rejuvenate the skin and increase the protective layer against irradiation by ultraviolet radiation (UVR). More specifically it provides terpenes and terpenoids as ingredients that work as persistent UVR blockers. Terpenes and terpenoid compounds support the growth of skin, skin tissue and keratinocytes and additional UVR-blocking by reason of increased stratum corneum thickness and loricrin content. Both terpenes and terpenoids may be applied topically or orally at oral or topical concentrations from about 6 mg to about 600 mg per kilogram of body weight per day effective to stimulate growth of the skin layer and prevent damage from ultraviolet radiation (UVR).Type: ApplicationFiled: September 17, 2010Publication date: June 30, 2011Inventors: Ivica Labuda, Fredric Jay Burns
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Publication number: 20110144200Abstract: The invention describes the preparation and use of carotenoid and epi-lutein compositions to treat various ocular diseases.Type: ApplicationFiled: December 8, 2010Publication date: June 16, 2011Inventor: Thomas Eidenberger
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Patent number: 7947687Abstract: This invention comprises antineoplastic curcumin derivatives and methods of preparation and use thereof. Particular reference is made to the following isomeric compounds wherein R1, R2, and R3 are selected from the group consisting of H, OH, OCH3, and COOH.Type: GrantFiled: October 29, 2007Date of Patent: May 24, 2011Inventor: Byron C Robinson
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Publication number: 20110118359Abstract: A method for enhancing endurance and/or for removing fatigue by administering to a subject in need thereof a composition containing an effective amount of nootkatone. The method may be further combined with exercise.Type: ApplicationFiled: January 18, 2011Publication date: May 19, 2011Applicant: Kao CorporationInventors: Takatoshi MURASE, Yoshihiko Minegishi
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Publication number: 20110098350Abstract: Novel substituted cyclohexylidene-ethylidene-octahydro-indene compounds and compositions comprising the same are described. The compounds exhibit profound anti-proliferative effects, in comparison to other compounds known for their anti-cancer and anti-hyperproliferative ability. Methods of use of such compounds and compositions are described for treating a variety of cancers, inflammatory and other hyperproliferative diseases and disorders.Type: ApplicationFiled: June 16, 2009Publication date: April 28, 2011Inventors: Shimon Ben Shabat, Amnou Sintov
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Publication number: 20110092584Abstract: The present invention relates to cannabinoic quinone compounds, and especially to their medical use. In particular five cannabinoic quinones, designated HU-331, HU-336, HU-345, HU-395 and HU-396 are herein described as active agents in pharmaceutical compositions. Said compounds and compositions thereof are intended for the treatment of inflammatory, infectious, auto-immune and particularly hyperproliferative disorders. Thus, the compounds of the invention may be used as anti-tumor agents, or for the treatment of cancer. Furthermore, three of these compounds, HU-345, HU-395 and HU-396, are novel cannabinoic quinones and thus are also claimed herein.Type: ApplicationFiled: January 14, 2005Publication date: April 21, 2011Applicant: YISSUM RESEARCH DEVELOPMENT COMPANY OF THE HEBREW UNIVERSITY OF JERUSALEMInventors: Raphael Mechoulam, Natalya M. Kogan, Ruth Rabinowitz, Michael Schlesinger
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Publication number: 20110092582Abstract: Novel terpenes and macrocycles are activators of TGR5 and can be used for the prevention and/or treatment of Diabetes Type 2, obesity, neuropathy and/or nephropathy.Type: ApplicationFiled: May 8, 2009Publication date: April 21, 2011Inventors: Delphine Jacquot, Oliver Poeschke, Christa Burger
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Publication number: 20110081330Abstract: The present invention relates to compositions containing plant gums and one or more fat-soluble active ingredients, wherein the composition comprises less than 40 weight-% oil, based on the total composition in dry matter. These compositions can be used for the enrichment, fortification and/or coloration of food beverages, animal feed, cosmetics or pharmaceutical compositions. The present invention also refers to the preparation of such compositions. The present invention furthermore refers to a process for the manufacture of a beverage by mixing the compositions with ingredients of beverages. The present invention also refers to beverages obtainable by this process.Type: ApplicationFiled: June 3, 2009Publication date: April 7, 2011Inventors: Andrea Hitzfeld, Bruno H. Leuenberger, Olivia Vidoni
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Publication number: 20110077307Abstract: There is provided pet food comprising astaxanthin and/or an ester thereof as an active component and having an effect of deodorizing excrement such as urine and feces, effects of improving sleep, sensibility such as perception and cognition, and visual sense, and an effect of treating, improving or preventing diabetes and diabetic complications. The pet food can deodorize excrement such as urine and feces, improve sleep, sensibility such as perception and cognition, and visual sense, and treat, improve or prevent diabetes and diabetic complications.Type: ApplicationFiled: December 7, 2010Publication date: March 31, 2011Applicant: FUJI CHEMICAL INDUSTRY CO., LTD.Inventors: Tomoaki HONDA, Jiro TAKAHASHI
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Publication number: 20110027223Abstract: The present invention is directed to a method of inducing platelet production that includes contacting a megakaryocyte with an electrophilic compound under conditions effective to induce platelet production by the contacting megakaryocyte. Methods of treating a patient for low platelet levels, increasing the circulating half-life of platelets, and improving the quality (activity) of platelets are also disclosed herein, which involve administering the electrophilic compound to a patient an effective amount to achieve the desired effect. Pharmaceutical compositions and therapeutic systems are also disclosed for carrying out these therapeutic treatments.Type: ApplicationFiled: October 29, 2008Publication date: February 3, 2011Applicant: UNIVERSITY OF ROCHESTERInventors: Richard P. Phipps, Jamie O'Brien
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Publication number: 20110020316Abstract: Beneficial and synergistic effects for alleviating joint pain and symptoms of osteoarthritis and/or rheumatoid arthritis have been found with krill oil and/or marine oil in combination with other active constituents, including astaxanthin and polymeric hyaluronic acid or sodium hyaluronate (hyaluronan) in an oral dosage form.Type: ApplicationFiled: July 21, 2010Publication date: January 27, 2011Applicant: U.S. Nutraceuticals, LLC d/b/a Valensa InternationalInventors: John A. Minatelli, W. Stephen Hill, Swati Sebastian Thomas, Lingan Rajendran, Rudi E. Moerck
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Publication number: 20110002905Abstract: The present invention relates to compositions containing one or more proteins, one or more polysaccharides and one or more fat-soluble active ingredients and their use for the enrichment, fortification and/or coloration of food beverages, animal feed and/or cosmetics.Type: ApplicationFiled: February 23, 2010Publication date: January 6, 2011Applicants: DSM IP ASSETS B.V., FUDAN UNIVERSITYInventors: Chyi-Cheng CHEN, Ping Yao, Bruno H. Leuenberger, Gerhard Wagner, Keke Xu, Shi-Kchen Chen
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Publication number: 20100303907Abstract: The present invention refers to a process for obtaining a standardized extract having antinociceptive, anti-inflammatory and antipyretic properties, from at least one part of a plant of genus Aleurites. Furthermore, the present invention provides a pharmaceutical composition comprising an active ingredient of a pharmaceutically efficient quantity of standardized extract from at least one part of the plant of genus Aleurites. Finally, the present invention describes a method of treatment and use of the said extract, isolated or in a pharmaceutical composition, for the prevention, control or treatment of painful, inflammatory or febrile affections.Type: ApplicationFiled: October 24, 2008Publication date: December 2, 2010Applicants: EUROFARMA LABORATÓRIOS LTDA., FUNDACÃO UNIVERSIDADE DO VALE DO ITAJAÍInventors: Valdir Cechinel Filho, Tania Mari Belle Bresolim, Christiane Meire Bittencourt, Marcia Maria De Souza, Ruth Meri Lucinda, Nara Lins Meira Quintao, Ticiana Camila Mora, Carlos Picolli, Marcello Creado Pedreira, Marcelo Eidi Nita, Rodrigo Spricigo
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Publication number: 20100279963Abstract: Derivatives of dicarbonyl compounds having antitumor and antibiotic activity which can be used as anticancer agents.Type: ApplicationFiled: July 1, 2010Publication date: November 4, 2010Applicant: Abraxis BioScience, LLCInventors: Chunlin Tao, Qinwei Wang, Vuong Trieu, Neil Desai, Patrick Soon-Shiong
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Publication number: 20100273801Abstract: The invention relates to compouns derived from betulin, and to the use thereof as antibacterial agents in pharmaceutical and cosmetic applications.Type: ApplicationFiled: June 6, 2007Publication date: October 28, 2010Applicant: Valition teknillinen tutikimuskeskusInventors: Jari Yli-Kauhaluoma, Salme Koskimies, Sami Alakurtti, Taru Mäkelä, Päivi Tammela
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Publication number: 20100272763Abstract: A skin external preparation includes an oil-in-water emulsion composition. The emulsion composition contains first oil droplet particles having a minimum particle diameter of 200 nm or more and second oil droplet particles having an average particle diameter of 70 nm or less. The first oil droplet particles contain a first functional oil component, and the second oil droplet particles contain a second functional oil component.Type: ApplicationFiled: December 11, 2008Publication date: October 28, 2010Applicant: FUJIFILM CORPORATIONInventor: Yoshisada Nakamura
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Publication number: 20100260811Abstract: The invention relates to novel powderous, water-soluble compositions of fat-soluble substances and aqueous solutions or emulsions thereof, wherein the fat-soluble substance(s) are encapsulated as inner (discontinuous phase within an outer (continuous) phase of a matrix substance.Type: ApplicationFiled: June 21, 2010Publication date: October 14, 2010Inventor: Elger FUNDA
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Publication number: 20100233256Abstract: The present invention relates to methods and compositions effective in lowering blood pressure. The compositions comprise, as active ingredients, an effective amount of a combination of lycopene and a carotenoid, e.g., lutein. In a preferred embodiment, the lycopene and lutein together provide a synergistic therapeutic effect at lowering blood pressure. The compositions can further comprise additional agents such as carotenoids and other phytochemicals found in tomato oleoresin.Type: ApplicationFiled: July 10, 2008Publication date: September 16, 2010Applicant: LYCORED LTD.Inventors: Morris Zelkha, Esther Paran, Keren Hirsch
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Publication number: 20100221372Abstract: The present invention relates in general to the field of inflammation. In particular the present invention relates to the use of natural compounds for the preparation of a product to treat or prevent inflammation. For example an extract of wolfberry was shown to have anti-inflammatory properties. One embodiment of the present invention relates to the use of a primary composition comprising wolfberries or a part thereof for the preparation of a product to treat or prevent inflammation.Type: ApplicationFiled: September 12, 2008Publication date: September 2, 2010Inventors: Karine Vidal, Stéphanie Blum-Sperisen, David Philippe, Olivier Ballevre, Peter Bucheli, Junkuan Wang
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Publication number: 20100196493Abstract: The invention relates to the use of at least one viscous compound, the viscosity of which is greater than 5 Pa·s?1, to substantially prevent the degradation of a substance sensitive to temperatures of 20° C. to 100° C. and/or pressures of 106 to 107 Pa and/or a relative humidity of 60% to 100%, contained in a powder composition, the powder composition containing particles including: a core containing the sensitive substance and at least one viscous compound as impregnating agent for the sensitive substance and a coating for the core, which contains at least one viscous compound as sticking agent.Type: ApplicationFiled: July 18, 2008Publication date: August 5, 2010Applicant: INNOV'IAInventor: Pierre Buisson
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Publication number: 20100183537Abstract: Compositions that provide health benefits and methods regarding same are presented. In an embodiment, the present invention provides a primary composition comprising at least one carotenoid-containing material, enriched in Z isomers of the carotenoid compound. For example, the carotenoid-containing material contains by weight a greater percentage of an isomer selected from the group consisting of 5-Z, 9-Z and combinations thereof than of 13-Z isomer.Type: ApplicationFiled: August 7, 2007Publication date: July 22, 2010Applicant: NESTEC S.A.Inventors: Karlheinz Bortlik, Pierre Lambelet, Myriam Richelle
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Publication number: 20100166896Abstract: Methods for repelling flying or biting insects from an area, a human, or an animal subject are provided. The methods include treating the area, or applying to a subject or to a device worn by the subject seychellene, ?-guaiene, and ?-bulnesene, or a mixture thereof. Additional compounds including ?-caryophyllene, isocaryophyllene, ?-caryophyllene oxide, ?-caryophyllene ketone, ?-humulene, ?-patchoulene, ?-patchoulene, ?-elemene, (+)-longipinene, (?)-isolongifolene, (+)-longifolene, and linalool, clove oil, and/or patchouli oil may also be used.Type: ApplicationFiled: December 30, 2008Publication date: July 1, 2010Applicant: STERLING INTERNATIONAL INC.Inventors: Qinghe Zhang, Armenek Margaryan, Rodney G. Schneidmiller
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Publication number: 20100152238Abstract: Novel cannabinoid-derived quinone derivatives (quinonoid derivatives) having a substituted hydroxyl group, pharmaceutical compositions comprising same and uses thereof as anti-proliferative agents, are provided.Type: ApplicationFiled: March 5, 2008Publication date: June 17, 2010Applicant: Yissum Research Development Company of The Hebrew University of JerusalemInventors: Raphael Mechoulam, Natalya Kogan
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Publication number: 20100144685Abstract: This document involves methods and materials related to inhibiting cyclin D polypeptide activity. For example, this document provides methods and materials that can be used to (1) identify mammals or cells in need of cyclin D polypeptide inhibition and (2) administer an agent capable of inhibiting cyclin D polypeptide activity.Type: ApplicationFiled: October 10, 2007Publication date: June 10, 2010Inventors: Rodger E. Tiedemann, Alexander Keith Stewart, Aaron David Schimmer, Xinliang Mao
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Publication number: 20100113460Abstract: Disclosed are compounds having the ability to inhibit cytochrome P450 2A6, 2A13, and/or 2B6 and tobacco products comprising them. Also disclosed are pharmaceutical compositions comprising them.Type: ApplicationFiled: March 20, 2008Publication date: May 6, 2010Applicant: Givaudan SAInventors: Boris Schilling, Wolf D. Woggon, Antoinette Chougnet, Thierry Granier, Georg Frater, Andreas Hanhart
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Publication number: 20100080862Abstract: It is intended to provide compositions and foods for use in the treatment, prophylaxis, or amelioration of diseases or symptoms which can be treated, prevented or ameliorated by activating PPAR, in particular, insulin resistant diabetes and hyperlipidemia. Namely, medicinal compositions usable in treating, preventing or improving diseases or symptoms which can be treated, prevented or ameliorated by activation PPAR which contain humulones, isohumulones or lupulones or pharmaceutically acceptable salts or solvates thereof.Type: ApplicationFiled: September 10, 2009Publication date: April 1, 2010Inventors: Hiroaki YAJIMA, Yutaka Miura, Daisuke Fujiwara, Hideharu Odai, Keiji Kondo, Hajime Nozawa
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Publication number: 20100062040Abstract: A method of forming water soluble microparticles is disclosed that includes the steps of providing a water insoluble food supplement, mixing the food supplement in a water miscible polar solvent, heating the mixture to increase the solubility and dissolve the food supplement into the solvent to form a saturated solution, and streaming the solution into water to form a solvent-water mix such that microparticles of the food supplement are producedType: ApplicationFiled: August 21, 2009Publication date: March 11, 2010Inventors: Donald E. Ackley, Eugene Tu
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Patent number: 7666900Abstract: To provide a pharmaceutically effective prophylactic/preventive agent for low-HDL cholesterolemia, focusing on an HDL-generating mechanism. The ABCA1 stabilizer of the present invention contains a bisphenol-type compound selected form probucol spiroquinone, probucol diphenoquinone, and probucol bisphenol as an effective ingredient. The ABCA1 stabilizer can continuously and stably express ABCA1 by a mechanism quite different from that of conventional processes, and thus is useful as prophylactic/preventive agent for low-HDL cholesterolemia or arteriosclerosis.Type: GrantFiled: December 22, 2004Date of Patent: February 23, 2010Assignee: Hykes Laboratories LLCInventors: Shinji Yokoyama, Maki Tsujita, Reijiro Arakawa, Tomoji Aotsuka
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Publication number: 20100041607Abstract: The present invention relates to unctuous composition containing at least one solid active ingredient, at least one hydrophobic protective colloid and at least one edible oil. The active ingredient is preferably a carotenoid. The preferred protective colloids are prolamines. The invention compositions are simple to produce, have good bioavailability and dyestuff yield, and are used an addition to animal feed agents, foods, and dietary supplements and pharmaceutical and cosmetic agents.Type: ApplicationFiled: January 15, 2008Publication date: February 18, 2010Applicant: BASF SEInventors: Jesper Feldthusen Jensen, Christian Köpsel, Helmut Auweter, Ingrid Martin, Angelika-Maria Pfeiffer, Erik Lüddecke, Dieter Feuerstein
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Publication number: 20100028318Abstract: The present invention has its object to provide a safer and highly effective composition capable of relieving or preventing xerostomia. The present invention relates to an agent for relieving or preventing xerostomia comprising an oxidized coenzyme Q and/or a reduced coenzyme Q as active ingredients, a composition containing the agent for relieving or preventing xerostomia in a form of a food product, a health food, a dietary supplement, a supplement, an oral health care product, a medicament, a quasi drug, a pet food, a feed or the like, and a method for treating xerostomia and a method for reducing risks of xerostomia comprising administering the composition.Type: ApplicationFiled: January 31, 2008Publication date: February 4, 2010Applicants: KANEKA CORPORATIONInventors: Ichiro Saito, Kenji Fujii, Kazuya Hamada
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Publication number: 20100021511Abstract: The present invention provides: a dispersion composition including a carotenoid-containing oily component, the dispersion composition being obtained by mixing an aqueous dispersion containing emulsion particles containing the carotenoid-containing oily component and a phospholipid or a derivative thereof with an aqueous composition containing ascorbic acid or a derivative thereof and an oily component that is 20% by mass or less relative to the mass of the whole dispersion composition, and the dispersion composition having emulsion particles having an average particle diameter of 200 nm or less; a dispersion composition including a carotenoid-containing oily component, the dispersion composition being obtained by mixing an aqueous dispersion containing emulsion particles containing a carotenoid-containing oily component and a phospholipid or a derivative thereof with an aqueous composition containing ascorbic acid or a derivative thereof and a pH adjusting agent, and the dispersion composition having a pH valType: ApplicationFiled: December 27, 2007Publication date: January 28, 2010Applicant: FUJIFILM CORPORATIONInventors: Tatsuo Kawabuchi, Toshiaki Kubo, Manabu Ogawa, Keiichi Suzuki, Tomoko Tashiro, Yukio Sudo
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Publication number: 20090312434Abstract: The present invention relates to the use of 3,5-seco-4-nor-cholestane derivatives for obtaining a cytoprotective drug, with the exception of a neuroprotective drug, notably a cardioprotective or hepatoprotective drug.Type: ApplicationFiled: February 23, 2007Publication date: December 17, 2009Applicant: TROPHOSInventors: Rebecca Pruss, Bruno Buisson, Thierry Bordet
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Patent number: 7629387Abstract: Compounds, compositions, and methods for controlling an arthropod pest population that employ an eremophilane sesquiterpene parent structure are presented. The compounds have minimal adverse or toxic effects on humans, non-human animals, and the natural environment. The compounds may be isolated from natural sources, semi-synthesized from naturally occurring compounds, or completely synthesized. The compounds may be applied directly to a pest, or the locus of a pest, and function as topical or ingestible toxins. Eremophilane sesquiterpenes 13-hydroxy-valencene, valencene-11,12-epoxide, valencene-13-aldehyde, and nootkatone-1,10-11,12-diepoxide are exemplary compounds.Type: GrantFiled: April 13, 2005Date of Patent: December 8, 2009Assignees: The United States of America as represented by the Secretary of the Department of Health and Human Services, State of Oregon acting by and through the State Board of Higher Education on behalf of Oregon State UniversityInventors: Gary O. Maupin, Joseph Karchesy, Nicholas A. Panella, Marc C. Dolan
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Publication number: 20090297492Abstract: The present invention provides a method for improving cognitive performance that encompasses all of: sense; perception; recognition; judgment; and action or suppression; and is based on a higher brain function. The method for improving cognitive performance of the present invention includes administering astaxanthin and/or an ester thereof to an individual. The cognitive performance is, for example, at least one selected from the group consisting of judging ability, spatial attention-allocating ability, concentration on the recognition of surroundings, and agility as determined by speed and/or accuracy of a body reaction which requires a higher brain function.Type: ApplicationFiled: May 29, 2009Publication date: December 3, 2009Applicant: YAMAHA HATSUDOKI KABUSHIKI KAISHAInventors: Akira SATOH, Shinji TSUJI
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Publication number: 20090246152Abstract: The invention relates to agents for sequestering serum aging factors, and methods for using the same. More particularly, the invention relates to agents termed herein “Naractin” to denote any one of several naturally-occurring arNOX inhibitors either present in N. tazetta powder or capable of augmenting N. tazetta powder to an inhibitory level comparable to that of the fresh N. tazetta extracts, and to methods for using “Naractins” to prevent or treat disorders and complications of disorders resulting from cell damage caused by an aging-related isoform of NADH oxidase (arNOX). In one exemplary embodiment the agents of the invention comprise at least one naturally occurring Naractin. Such naturally occurring naractins are also capable of augmenting the anti-arNOX effect of other naturally occurring arNOX inhibitory agents.Type: ApplicationFiled: March 28, 2008Publication date: October 1, 2009Applicant: Nu Skin International, Inc.Inventors: Dale Kern, Christiaan Meadows
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Publication number: 20090246153Abstract: A composition and method having anti-aging properties is provided. The composition comprises an arNOX inhibitory agent present in a natural plant extract and is useful topically as a cosmetic. The symptoms of aging including lines, wrinkles, hyperpigmentation, dehydration, loss of elasticity, angioma, dryness, itching, telangietasias, actinic purpura, seborrheic keratoses and actinic keratoses. The invention may be used multiple times a day without deleterious effects.Type: ApplicationFiled: March 28, 2008Publication date: October 1, 2009Applicant: Nu Skin International, Inc.Inventor: Dale Kern
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Publication number: 20090203799Abstract: A novel composition for delivering carotenoids (e.g. ?- and ?-carotene, lycopene) and/or other physiologically active ingredients to the colon of humans after ingestion and for producing liquid food compositions insusceptible to polyphenol-protein reactions can be obtained by encapsulating said active ingredients with pectin, in particular with low-methoxylated pectin.Type: ApplicationFiled: April 10, 2009Publication date: August 13, 2009Inventors: Reinhold Carle, Andreas Schieber, Susanne Mutter
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Publication number: 20090197971Abstract: A method for improving the flavor of an astaxanthin-containing extract of the present invention includes the steps of: mixing 0.5 to 1000 parts by weight of ethanol and 1 part by weight of the astaxanthin-containing extract so as to obtain an ethanol mixture; collecting a solid precipitated from the ethanol mixture obtained; and drying the solid collected. In particular, the astaxanthin-containing extract, i.e., the starting material, is an extract from a green alga.Type: ApplicationFiled: January 28, 2009Publication date: August 6, 2009Applicant: YAMAHA HATSUDOKI KABUSHIKI KAISHAInventors: Rie SUZUKI, Hiroyuki SUGIYAMA, Asako SAIKI
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Publication number: 20090181901Abstract: The present invention relates to compositions and methods of use to increase the bioavailability of a carotenoid in a subject. The compositions include a carotenoid and either an anthocyanin or a compound having at least one —SH group or combinations of both an anthocyanin and a compound having at least one —SH group and mixtures thereof. The compositions provide that when the composition is administered, the resulting bioavailability of the carotenoid is increased relative to a carotenoid composition that is without either the anthocyanin, is without the compound having at least one —SH group or is without the combination of an anthocyanin/a compound having at least one —SH group and mixtures thereof.Type: ApplicationFiled: November 13, 2008Publication date: July 16, 2009Inventor: Thomas Eidenberger
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Publication number: 20090118227Abstract: The present invention is directed to carotenoid compositions and methods for inhibiting the growth of pathogenic bacteria or for preventing or treating bacterial infections in subjects by administration of an effective amount of astaxanthin and beta-carotene.Type: ApplicationFiled: September 9, 2008Publication date: May 7, 2009Inventors: Zeina Jouni, Zeina Makhoul
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Publication number: 20090105332Abstract: A compound having the structure of the formula (genus of compound 1 excluding Tashironin or Debenzoyltashironin) wherein, R1 is H or Bz when no more than three of R8, R9, R10 and R11 are H, or R1 is Bn, (C1-C4) alkyl, or CF3; R2 is H, (C1-C4) alkyl, halide, OC(O)(C1-C4)alkyl, OC(O)Ph, or OCF3; R3 is p-toluene sulfonyloxy, methane sulfonyloxy, C(O)(C1-C4)alkyl, or OC(O)(C1-C4)alkyl, bond ? is a single bond, and bond ? is a double bond or R3 is O, bond ? is a double bond and bond ? is a single bond; R4 is H, I, Br, Cl, Si(CH3)3, (C1-C4)alkyl, or OCF3; R5 is OH, OSi(CH3)3, O(C1-C4) alkyl, or OCF3, and bond ? is a single bond, or R5 is O and bond ? is a double bond; R6 is H, (C1-C4) alkyl, or CF3; R7 is H, OH, (C1-C4)alkyl, CH2OBn, CH2O(C1-C4)alkyl, CH2OH, halide, CH2OCF3 or OCF3 and bond ? is a single bond, or R7 is CH2 and bond ? is a double bond; R8, R9, and R10 are each independently H, (C1-C4)alkyl, halide, OH, or OCF3; R11 is H, (C1-C4)alkyl, halide, OH, or OCF3 and bond ? is a single bond; R12 is H, (Type: ApplicationFiled: December 20, 2005Publication date: April 23, 2009Applicant: THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OFInventors: Samuel J. Danishefsky, Silas P. Cook
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Publication number: 20090099255Abstract: [Object] In recent years, life style-related diseases, particularly circulatory system diseases caused by the tendency toward high caloric diet, the change in life style, lack of exercise, stress and so on increased and have became a serious social problem. These diseases are caused mainly by injures in blood vessels. To prevent injures in blood vessels, there has been required a vascular endothelial cell-protecting agent and a food having an effect of protecting vascular endothelial cells.Type: ApplicationFiled: March 31, 2006Publication date: April 16, 2009Inventors: Naoki Higashi, Jiro Takahashi
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Publication number: 20090069442Abstract: The present invention provides therapeutic agents for sensory disorders represented by the following formula (1): [wherein R1, R2, and R3 each represent a hydrogen atom or a methyl group, and X represents a linear or branched C10-C28 alkylene or alkenylene group]. The cyclohexenone long chain alcohol of the present invention improves hyperalgesia or hypoalgesia, and thus is useful as therapeutic agents for sensory disorders. Sensory disorders that can be prevented or treated by the present invention include chronic intractable pain, neurogenic pain, reduction of pain threshold caused by nerve injuries, hypesthesia or hyperesthesia caused by diabetes and nerve injuries, and the like.Type: ApplicationFiled: January 18, 2006Publication date: March 12, 2009Inventors: Hirohito Shiomi, Yutaka Tamura, Bang Luu, Masashi Yamada, Keizou Koyama, Hiroto Suzuki
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Publication number: 20090061048Abstract: A complex coacervate delivery system is provided which encapsulates lipophilic nutrients such as, for example, fish oils high in omega-3 fatty acids. The complex coacervate delivery system protects the lipophilic nutrient from degradation, e.g., oxidation and hydrolysis, and also reduces or eliminates the unpleasant taste and odor of the lipophilic nutrient. The complex coacervate delivery system upon ingestion is operative to substantially release the lipophilic nutrient in the lower gastrointestinal tract in a pH-controlled manner. The complex coacervate delivery system may be included in a food or beverage product having a pH value within the range of about 1.5 to about 5.0.Type: ApplicationFiled: August 28, 2007Publication date: March 5, 2009Applicant: PepsiCo, Inc.Inventors: Daniel S. Kohane, Yoon Yeo, Peter Given, Robert S. Langer
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Publication number: 20090062401Abstract: The present invention relates to compounds having a decaline scaffold, pharmaceutically acceptable salts of these compounds and pharmaceutical compositions containing at least one of these compounds together with pharmaceutically acceptable carrier, excipient and/or diluents. Said decaline-derived compounds can be used for prophylaxsis and/or treatment of diabetes mellitus type I, diabetes mellitus type II, tuberculosis and other infectious diseases, proliferative diseases, cancer, neurodegenerative diseases, obesity, cognitive dysfunctions and metabolic syndromes.Type: ApplicationFiled: December 28, 2005Publication date: March 5, 2009Applicants: UNIVERSITAT DORTMUND, MAX-PLANCK-GESELLSCHAFT ZUR FODERUNG DER WISSENSCHAFTEN E.V., UNIVERSITAT BERNInventors: Alex Odermatt, Herbert Waldmann, Michael Scheck, Marcus A. Koch
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Publication number: 20090047304Abstract: An increase in body fat is one of main causes of life-style-related diseases such as hypertension, insulin tolerance and hyperlipemia. A composition for body fat reduction is provided which inhibits body fat from decreasing or decreasing which and which is effective in the treatment and prevention of adult diseases a cause of which is body fat. Also, provided are a medicine and a food each containing the composition. The composition for body fat reduction comprises (A) astaxanthin and (B) at least one of active ingredient, an adsorbent and a solubilizer, a composition comprises (A) Haetmatococcusalga extract containing astaxanthin and (B) at least one of active ingredient, an adsorbent and a solubilizer, and a medicine and food, each containing the composition are provided.Type: ApplicationFiled: December 2, 2005Publication date: February 19, 2009Inventors: Jiro Takahashi, Eiji Yamashita, Makoto Fukamauchi, Isao Tanaka